1. Supportive care during pediatric hematopoietic stem cell transplantation: beyond infectious diseases. A report from workshops on supportive care of the Pediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT)
- Author
-
Krzysztof Kałwak, Peter Bader, Alice Bertaina, Riitta Niinimäki, Tayfun Güngör, Brenda Gibson, Marianne Ifversen, Marc Ansari, Christina Diaz de Heredia, Akif Yesilipek, Tiago Nava, Jerry Stein, Jochen Buechner, E. Trigoso, Jacek Wachowiak, Marco Deiana, Koray Yalcin, Christina Peters, Halvard Boenig, Simone Cesaro, Isaac Yaniv, Gergely Kriván, Kim Vettenranta, Toni Matic, Dominik Turkiewicz, Roland Meisel, Michaela Kuhlen, Giovanna Lucchini, Shahrzad Bakhtiar, Andre Willasch, Luisa Sisinni, Petr Sedlacek, Daphna Hutt, Thomas Lehrnbecher, Anita Lawitschka, Adriana Balduzzi, Jean Hugues Dalle, Tamara Diesch, Arnaud Dalissier, Selim Corbacioglu, Andrea Jarisch, Ulrike Falkenberg, Nava, T, Ansari, M, Dalle, J, de Heredia, C, Güngör, T, Trigoso, E, Falkenberg, U, Bertaina, A, Gibson, B, Jarisch, A, Balduzzi, A, Boenig, H, Krivan, G, Vettenranta, K, Matic, T, Büchner, J, Kalwak, K, Lawitschka, A, Yesilipek, A, Lucchini, G, Peters, C, Turkiewicz, D, Niinimäki, R, Diesch, T, Lehrnbecher, T, Sedlacek, P, Hutt, D, Dalissier, A, Wachowiak, J, Yaniv, I, Stein, J, Yalçin, K, Sisinni, L, Deiana, M, Ifversen, M, Kuhlen, M, Miesel, R, Bakhtiar, S, Cesaro, S, Willasch, A, Corbacioglu, S, and Bader, P
- Subjects
HEPATIC VENOOCCLUSIVE DISEASE ,medicine.medical_specialty ,bone marrow transplantation ,medicine.medical_treatment ,MEDLINE ,ENTERAL NUTRITION ,Hematopoietic stem cell transplantation ,ORAL MUCOSITIS ,Communicable Diseases ,03 medical and health sciences ,bone marrow transplantation, pediatric, supportive care ,0302 clinical medicine ,Bone Marrow ,Internal medicine ,IRON OVERLOAD ,Mucositis ,Humans ,Medicine ,Child ,Intensive care medicine ,SYNDROME/VENO-OCCLUSIVE DISEASE ,ANTICIPATORY NAUSEA ,Transplantation ,Hematology ,business.industry ,Marrow transplantation ,Research ,Hematopoietic Stem Cell Transplantation ,SEVERITY CRITERIA ,medicine.disease ,supportive care, hematopoietic stem cell transplantation, pediatric ,URSODEOXYCHOLIC ACID ,Europe ,supportive care ,Leukemia ,pediatric ,ANTINEOPLASTIC MEDICATION ,surgical procedures, operative ,Parenteral nutrition ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Bone marrow ,business ,CHEMOTHERAPY-INDUCED NAUSEA ,030215 immunology - Abstract
Hematopoietic stem cell transplantation (HSCT) is currently the standard of care for many malignant and nonmalignant blood diseases. As several treatment-emerging acute toxicities are expected, optimal supportive measurements critically affect HSCT outcomes. The paucity of good clinical studies in supportive practices gives rise to the establishment of heterogeneous guidelines across the different centers, which hampers direct clinical comparison in multicentric studies. Aiming to harmonize the supportive care provided during the pediatric HSCT in Europe, the Pediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT) promoted dedicated workshops during the years 2017 and 2018. The present paper describes the resulting consensus on the management of sinusoidal obstructive syndrome, mucositis, enteral and parenteral nutrition, iron overload, and emesis during HSCT.
- Published
- 2020