57 results on '"Chris Healey"'
Search Results
2. Dissipative and Dispersive Optomechanics in a Nanocavity Torque Sensor
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Marcelo Wu, Aaron C. Hryciw, Chris Healey, David P. Lake, Harishankar Jayakumar, Mark R. Freeman, John P. Davis, and Paul E. Barclay
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Physics ,QC1-999 - Abstract
Dissipative and dispersive optomechanical couplings are experimentally observed in a photonic crystal split-beam nanocavity optimized for detecting nanoscale sources of torque. Dissipative coupling of up to approximately 500 MHz/nm and dispersive coupling of 2 GHz/nm enable measurements of sub-pg torsional and cantileverlike mechanical resonances with a thermally limited torque detection sensitivity of 1.2×10^{−20} Nm/sqrt[Hz] in ambient conditions and 1.3×10^{−21} Nm/sqrt[Hz] in low vacuum. Interference between optomechanical coupling mechanisms is observed to enhance detection sensitivity and generate a mechanical-mode-dependent optomechanical wavelength response.
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- 2014
- Full Text
- View/download PDF
3. Energy efficiency driven by a storage model and analytics on a multi-system semantic integration.
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Domitille Couloumb, Charbel El Kaed, Ayush Garg 0004, Chris Healey, Jonathan Healey, and Stuart Sheehan
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- 2017
- Full Text
- View/download PDF
4. Development of the 'Teamwork in Endoscopy Assessment Module for Endoscopic Non-Technical Skills' (TEAM-ENTS) behavioral marker system
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Srivathsan, Ravindran, Rebecca, Cavilla, Hutan, Ashrafian, Adam, Haycock, Chris, Healey, Mark, Coleman, Steph, Archer, Ara, Darzi, Siwan, Thomas-Gibson, and Emilia, Wronska
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Gastroenterology - Abstract
Background Non-technical skills (NTS) are integral to team performance and subsequent quality and safety of care. Behavioral marker systems (BMSs) are now increasingly used in healthcare to support the training and assessment of team NTS. Within gastrointestinal endoscopy, this is an area of novel research. The aims of this study were to define the core relevant NTS for endoscopy teams and develop a preliminary framework for a team-based BMS known as TEAM-ENTS (Teamwork in Endoscopy Assessment Module for Endoscopic Non-Technical Skills). Methods This study was conducted in two phases. In phase 1, a literature review of team-based BMSs was performed to inform an interview study of core endoscopy team members. Cognitive task analysis was used to break down the NTS relevant to endoscopy teams. Framework analysis generated the structure for the preliminary TEAM-ENTS framework. In phase 2, a modified Delphi process was undertaken to refine the items of the framework. Results Seven consultant endoscopists and six nurses were interviewed. The final coding framework consisted of 88 codes grouped into five overarching categories. In total, 58 participants were recruited to the Delphi panel. In the first round, nine elements and 37 behavioral descriptors did not meet consensus. Following item adjustment, merging and deletion, all remaining items met consensus thresholds after the second round. The refined TEAM-ENTS BMS consists of five categories, 16 elements, and 47 behavioral descriptors. Conclusions The refined TEAM-ENTS behavioral marker system was developed to reflect the core NTS relevant to endoscopy teams. Future studies will aim to fully validate this tool.
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- 2022
5. National census of UK endoscopy services 2021
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Srivathsan Ravindran, Siwan Thomas-Gibson, Madeline Bano, Emma Robinson, Anna Jenkins, Sarah Marshall, Hutan Ashrafian, Ara Darzi, Mark Coleman, and Chris Healey
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Hepatology ,Gastroenterology - Abstract
IntroductionThe Joint Advisory Group on Gastrointestinal (GI) Endoscopy (JAG) biennial census provides a unique view of UK endoscopy. The 2021 census was conducted to understand the impact of ongoing pressures, highlighted in the previous census, as well as COVID-19.MethodsThe census was sent to all JAG-registered services in April 2021. Data were analysed across the domains of activity, waiting time targets, workforce, COVID-19, safety, GI bleeding, anaesthetic support, equipment and decontamination. Statistical methods were used to determine associations between domain-specific outcome variables and core demographic data.Results321 services completed the census (79.2% response rate). In the first 3 months of 2021, 57.9% of NHS services met urgent cancer waits, 17.9% met routine waits and 13.4% met surveillance waits. Workforce redeployment was the predominant reason cited for not meeting targets. There were significant regional differences in the proportion of patients waiting 6 or more weeks (p=0.001). During the pandemic, 64.8% of NHS services had staff redeployed and there was a mean sickness rate of 8.5%. Services were, on average, at 79.3% activity compared with 2 years ago. JAG-accredited services are more likely to meet urgent cancer waits, with a lower proportion of patient waiting 6 weeks or more (p=0.03). Over 10% of services stated that equipment shortage interfered with service delivery.ConclusionsServices are adapting to continued pressure and there are signs of a focused response to demand at a time of ongoing uncertainty. This census’ findings will inform ongoing guidance from JAG and relevant stakeholders.
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- 2022
6. Joint Advisory Group on Gastrointestinal Endoscopy (JAG) framework for managing underperformance in gastrointestinal endoscopy
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Srivathsan Ravindran, Mark Coleman, Colin J Rees, Geoff Smith, Keith Siau, Chris Healey, and Siwan Thomas-Gibson
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Service (systems architecture) ,Hepatology ,business.industry ,Process (engineering) ,education ,Gastroenterology ,Endoscopy ,medicine.disease ,Coaching ,Patient safety ,Identification (information) ,Action plan ,Medicine ,Medical emergency ,business ,Accreditation ,Gastrointestinal endoscopy - Abstract
Underperformance can be defined as performance which persistently falls below a desired minimum standard considered acceptable for patient care. Within gastrointestinal endoscopy, underperformance may be multifactorial, related to an individual’s knowledge, skills, attitudes, health or external factors. If left unchecked, underperformance has the potential to impact on care and ultimately patient safety. Managing underperformance should be a key attribute of high-quality endoscopy service, as recognised in the Joint Advisory Group on Gastrointestinal Endoscopy (JAG) accreditation process. However, it is recognised that not all services have robust mechanisms to do this.This article provides the JAG position on managing underperformance in endoscopy, defined through a practical framework. This follows a stepwise process of detecting underperformance, verification, identification of additional causative factors, providing support and reassessment. Detection and verification of issues may require use of multiple evidence sources, including performance data, feedback and appraisal reports. Where technical underperformance is identified, this should be risk stratified by potential risk to patient safety. Support should be tailored to each individual case based on the type of underperformance detected, any causative factors with an action plan developed. Support may include coaching, mentoring, training and upskilling. Wider support from the medical director’s office or external services may also be required. Monitoring and reassessment is a crucial part of the overall process.
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- 2021
7. P195 Validation of the TEAM-ENTS (teamwork in endoscopy assessment module for endoscopic non-technical skills) framework
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Srivathsan Ravindran, Chris Healey, Mark Coleman, Hutan Ashrafian, Adam Haycock, Steph Archer, Ara Darzi, and Siwan Thomas-Gibson
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- 2022
8. P197 The endoscopy safety attitudes questionnaire (Endo-SAQ): validation and results
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Srivathsan Ravindran, Manmeet Matharoo, Chris Healey, Sarah Marshall, Paul Bassett, Mark Coleman, Hutan Ashrafian, Ara Darzi, and Siwan Thomas-Gibson
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- 2022
9. P194 Endoscopy safety incidents reported in a national data set – a human factors analysis
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Srivathsan Ravindran, Manmeet Matharoo, Chris Healey, Mark Coleman, Hutan Ashrafian, Ara Darzi, and Siwan Thomas-Gibson
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- 2022
10. P196 The national census of UK endoscopy services 2021
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Srivathsan Ravindran, Sarah Marshall, Chris Healey, Hutan Ashrafian, Ara Darzi, Mark Coleman, and Siwan Thomas-Gibson
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- 2022
11. PTH-61 Faecal Elastase may have a role in the investigation of iron deficiency anaemia
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Sadaf Dar, Faisal Shaikh, Susanna West, Ahmad Zakaria, Lionel Gracey-Whitman, David Clements, Chris Healey, Richard Shenderey, and Fahad Shaikh
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medicine.medical_specialty ,Endocrinology ,business.industry ,Internal medicine ,Elastase ,medicine ,Iron deficiency ,business ,medicine.disease - Published
- 2021
12. OTU-16 Development of the TEAM-ENTS (Teamwork in endoscopy assessment module for endoscopic non-technical skills) framework
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Mark Coleman, Steph Archer, Adam Haycock, Hutan Ashrafian, Chris Healey, Siwan Thomas-Gibson, Srivathsan Ravindran, and Ara Darzi
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Medical education ,Teamwork ,medicine.diagnostic_test ,media_common.quotation_subject ,medicine ,Technical skills ,Psychology ,media_common ,Endoscopy - Published
- 2021
13. PTU-19 The endoscopy safety attitudes questionnaire (ENDO-SAQ): Results of a pilot study
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Sarah Marshall, Mark Coleman, Siwan Thomas-Gibson, Chris Healey, Hutan Ashrafian, Srivathsan Ravindran, and Ara Darzi
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medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Physical therapy ,Medicine ,business ,Endoscopy - Published
- 2021
14. The national census of UK endoscopy services 2021
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Srivathsan, Ravindran, Siwan, Thomas-Gibson, Madeline, Bano, Emma, Robinson, Anna, Jenkins, Sarah, Marshall, Hutan, Ashrafian, Ara, Darzi, Mark, Coleman, and Chris, Healey
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Research and Innovation - Published
- 2022
15. Development of the Team-Ents (Teamwork in Endoscopy Assessment Module for Endoscopic Non-Technical Skills) Framework
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Stephanie Archer, R Cavilla, Mark Coleman, Chris Healey, Adam Haycock, Srivathsan Ravindran, Siwan Thomas-Gibson, Hutan Ashrafian, and Ara Darzi
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Teamwork ,Medical education ,medicine.diagnostic_test ,business.industry ,media_common.quotation_subject ,medicine ,Technical skills ,business ,Endoscopy ,media_common - Published
- 2021
16. Results Of An Endoscopy Safety Attitudes Questionnaire (ENDO-SAQ): A Pilot Study
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Mark Coleman, Siwan Thomas-Gibson, Hutan Ashrafian, Chris Healey, S Marshall, Srivathsan Ravindran, and Ara Darzi
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medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,medicine ,Physical therapy ,business ,Endoscopy - Published
- 2021
17. P68 Accreditation deferral at jag assessment: where do endoscopy services need to improve?
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Srivathsan Ravindran, Debbie Johnston, Chris Healey, Mark Coleman, Siwan Thomas-Gibson, Tim Shaw, and Dimple Keen
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Service (business) ,Work (electrical) ,Nursing ,education ,Workforce ,Patient experience ,Business ,Deferral ,health care economics and organizations ,Accreditation ,Test (assessment) ,Qualitative research - Abstract
Introduction Endoscopy services are expected to meet standards in four domains to achieve JAG accreditation: clinical quality, patient experience, training and workforce. At a JAG assessment, accreditation is ‘deferred’ if the service does not achieve the standards. The aim of this study was to analyse the standards on which NHS and independent sector (IS) services have their accreditation deferred to highlight themes for improvement and identify where support is needed. Methods A retrospective analysis of accreditation assessments from Nov 2016 to Jan 2020 was performed. Services were included if they had a deferral based on one or more standards. Where services had multiple reasons for deferral under one standard, records were de-duplicated. The proportion of deferrals per standard was calculated. Wilcoxon signed-rank test was used to compare deferral proportions between NHS and IS services. Results 276 services underwent assessment, 90 services had reasons for deferral, across 1255 standards. 73% of services included in the analysis were NHS. Table 1 shows the standards that were most and least likely to cause deferral across each domain: When NHS and IS services were compared, there were significant differences for deferral reasons in the clinical quality (p Conclusions This study provides insights into reasons for accreditation deferral between NHS and IS services. There are clear differences with NHS services more likely to defer on patient experience standards and IS services on clinical quality standards. Further work will focus on qualitative studies to investigate these findings further with the aim of supporting services seeking accreditation.
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- 2021
18. P70 The JAG survey of UK endoscopy services: results from the 2019 census
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Helen Griffiths, Ara Darzi, Hutan Ashrafian, Raphael Broughton, Srivathsan Ravindran, John Green, Chris Healey, Siwan Thomas-Gibson, and Tim Shaw
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Service (business) ,Response rate (survey) ,medicine.medical_specialty ,medicine.diagnostic_test ,Kruskal–Wallis one-way analysis of variance ,business.industry ,Census ,Endoscopy ,Family medicine ,Workforce ,medicine ,Chi-square test ,business ,Gastrointestinal endoscopy - Abstract
Introduction The Joint Advisory Group on Gastrointestinal endoscopy (JAG) conduct a biennial census to understand factors related to endoscopy quality, workforce and training across services in the UK. The study reports the results of the 2019 census. Methods A census of all UK JAG-registered services was conducted in April 2019. Questions were devised by an expert panel covering domains of activity, workforce and waiting times. Question items were informed by results of the previous census. Results were collated and analysed using Chi Square, Fisher’s exact and Kruskal Wallis tests. Results The response rate was 68.4%. A total of 2,133,541 endoscopic procedures were performed in 2018. In March 2019, 31,938 endoscopy lists were delivered (mean 99.2 ± 95.7 per service). The responding services employed 5,578 endoscopists (mean 17.32 ± 10.13, 12% non-medical), 1,366 trainees (mean 4.24 ± 6.43) and 12,680 nurses and allied health professionals (AHP) (mean 39.94 ± 284.81). There was a nursing and AHP vacancy rate of 7.29%. Region (p = 0.02) and service type (p Out of the lists performed by trainees, 51.9% were for training only. An average of 7.46 (± 1.45) oesophago-gastroduodenoscopies and 3.86 (± 0.85) colonoscopies were booked for each training list. There was a significant regional influence on number of trainee lists (p In the first 3 months of 2019, waiting time targets were met by 73.7% of services for urgent cancer, 68.7% for routine waits and 63.4% for surveillance waits. There was a significant difference in meeting targets between region (p Conclusions This census reflects the most extensive data regarding current UK endoscopy practice. There is evidence of service pressure, affecting wait times and training opportunities with significant regional and service-specific variability.
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- 2021
19. P71 A national survey of safety across UK endoscopy services
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Ara Darzi, Srivathsan Ravindran, John Green, Hutan Ashrafian, Chris Healey, Eleanor Wood, Helen Griffiths, Siwan Thomas-Gibson, Tim Shaw, Dimple Keen, and Raphael Broughton
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Response rate (survey) ,Service (business) ,medicine.medical_specialty ,Patient safety ,Quality management ,business.industry ,Kruskal–Wallis one-way analysis of variance ,SAFER ,Family medicine ,Chi-square test ,Medicine ,Census ,business - Abstract
Introduction The ‘Improving Safety and Reducing Error in Endoscopy’ (ISREE) strategy has highlighted the need to improve our understanding of factors related to safety across UK endoscopy. This study assesses aspects of safety that were included in the Joint Advisory Group on Gastrointestinal endoscopy (JAG) biennial census of services. Methods An expert panel devised questions across 7 themes that complemented JAG safety domains. These were incorporated into the census of UK JAG-registered services in April 2019. Census results were collated and analysed. Categorical data was analysed through Chi square, Fisher’s Exact, Kruskal Wallis and Friedman’s tests. Free text responses were analysed thematically. Results The response rate was 68.4%. Across March 2019, a total of 1535 patient safety incidents (PSIs) were reported (per service mean 4.80, SD 11.87). There was a significant difference in reporting dependent on incident type (p Anaesthetic-supported (AS) lists were unavailable to 27% of services. This varied amongst service type (p The majority of acute services have a gastrointestinal bleed (GIB) service (82.2%) but provision is significantly different between regions (p Overall, 66.1% of services reported having an effective strategy for supporting underperformance. More endoscopists require support for technical skills than non-technical skills (p = 0.001). Simulation provision was 49.1% across acute services, with significant regional differences (p = 0.001). Learning is shared following discussion of adverse events in 94.1% services. Patient feedback is used primarily to support learning, training and quality improvement. Conclusions This is the first survey of national endoscopy safety practice and highlights regional and service-specific variability. These results are important in guiding the ISREE strategy forwards in supporting safer UK endoscopy.
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- 2021
20. P12 National endoscopy database (NED): the first million
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Ramesh P. Arasaradnam, Chris Healey, Peter Rogers, David Beaton, Shiran Esmaily, James Docherty, Paul Dunckley, Thomas J. Lee, Matthew D. Rutter, Ashraf Rasheed, Srivathsan Ravindran, and Raphael Broughton
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Abdominal pain ,medicine.diagnostic_test ,Database ,business.industry ,Heartburn ,medicine.disease ,computer.software_genre ,Dysphagia ,Endoscopy ,Duodenitis ,medicine ,Vomiting ,Hernia ,medicine.symptom ,business ,Varices ,computer - Abstract
Introduction The National Endoscopy Database (NED) is populated by data extracted automatically from endoscopy reporting systems (ERSs) of endoscopy services in the UK. 406 out of 520 UK endoscopy sites are currently uploading. We aimed to provide an overview of oesophagogastroduodenoscopies (OGDs) stored on NED. Methods Data from all OGDs uploaded to NED from 2016 to the 28th January 2020 was accessed and analysed using the standard output from the NED website. Results 1,010,741 OGDs have been uploaded to NED. 651,270 of those are from 2019, compared to 281,883 in 2018 and 21,457 in 2017, indicating the ongoing roll-out of NED across the UK. 47% of procedures were performed on male patients, 52% on female and 1% unspecified. 27% of OGDs were performed on patients 13% of procedures were on in-patients, 65% on out-patients, while 22% were unspecified. 51% of procedures were routine, 37% urgent, 3% emergency, and 3% surveillance. 7% were not specified. 49% of procedures were unsedated. The most common indications were: Dyspepsia (17%), Heartburn/Reflux (15%), Anaemia (15%), Dysphagia (14%), Abdominal Pain (12%). Other frequent indications were: Weight Loss (7%), Nausea/Vomiting (6%), Melaena (5%), Haematemesis (3%), Barrett’s Oesophagus (3%), Varices Surveillance (2%). ‘Other’ was included in the indication field in 37% of OGDs. The most common diagnoses were: Normal (31%), Hiatus Hernia (27%), Non-erosive Gastritis (17%), Reflux Oesophagitis (11%). Other frequent diagnoses were: Barrett’s oesophagus (7%), Erosive Gastritis (6%), Gastric Polyp(s) (5%), Non-erosive Duodenitis (5%), Oesophageal Varices (2%), Erosive Duodenitis (2%), Duodenal Ulcer (2%), Gastric Ulcer (2%). ‘Other’ was included in the diagnosis field in 18% of OGDs. (NB: Multiple indications and diagnoses can be entered for a procedure, hence sum of percentages is greater than 100% for these categories) Conclusion The majority of procedures were performed in the ≥ 50 age group, peaking between ages 70 to 79, although a quarter of all procedures were performed in people younger than 50. Close to half of OGDs are performed without sedation. Procedure uploads to the NED continue to increase exponentially year on year. The volume of data and high proportion of sites uploading allows unparalleled insights into OGD practice in the UK.
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- 2021
21. ID: 3521970 DEVELOPMENT OF THE TEAM-ENTS (TEAMWORK IN ENDOSCOPY ASSESSMENT MODULE FOR ENDOSCOPIC NON-TECHNICAL SKILLS) FRAMEWORK
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Stephanie Archer, Hutan Ashrafian, Srivathsan Ravindran, Adam Haycock, Chris Healey, Siwan Thomas-Gibson, Mark Coleman, and Ara Darzi
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Teamwork ,Medical education ,medicine.diagnostic_test ,business.industry ,media_common.quotation_subject ,Gastroenterology ,medicine ,Radiology, Nuclear Medicine and imaging ,Technical skills ,business ,media_common ,Endoscopy - Published
- 2021
22. 'Case of the month': a novel way to learn from endoscopy-related patient safety incidents
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Siwan Thomas-Gibson, Manmeet Matharoo, Philip Berry, Tim Shaw, John O'Donohue, Matthew C Choy, Srivathsan Ravindran, Emma Robinson, Chris Healey, and Mark Coleman
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Hepatology ,medicine.diagnostic_test ,business.industry ,Shared learning ,Gastroenterology ,Case vignette ,Endoscopy ,medicine.disease ,Variety (cybernetics) ,03 medical and health sciences ,Patient safety ,0302 clinical medicine ,Workforce ,Health care ,Medicine ,030211 gastroenterology & hepatology ,030212 general & internal medicine ,Medical emergency ,business ,Gastrointestinal endoscopy - Abstract
Patient safety incidents (PSIs) are unintended or unexpected incidents which can or do lead to patient harm. The Joint Advisory Group on Gastrointestinal Endoscopy (JAG) acknowledges that PSIs should be reviewed by endoscopy services and learning shared among staff. It is recognised that more could be done to promote shared learning as outlined by the JAG ‘Improving Safety and Reducing Error in Endoscopy’ strategy. The ‘Case of the month’ series aims to provide a broad selection of cases and subsequent learning that can be shared among services and their workforce. This review focuses on five case vignettes that highlight a variety of PSIs in endoscopy. A structured approach, based on incident analysis methodology, is applied to each case to categorise PSIs and develop learning points. Learning is directed toward the individual, team and healthcare organisation. A selection of methods to disseminate learning at local, regional and national levels are also described.
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- 2020
23. Teamworking in endoscopy: a human factors toolkit for the COVID-19 era
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Siwan Thomas-Gibson, Mark Coleman, Ian D. Penman, Srivathsan Ravindran, Manmeet Matharoo, Chris Healey, and Sarah Marshall
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2019-20 coronavirus outbreak ,Process management ,Innovations and brief communications ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,education ,Pneumonia, Viral ,Viral transmission ,03 medical and health sciences ,Betacoronavirus ,0302 clinical medicine ,health services administration ,Medicine ,Humans ,natural sciences ,030212 general & internal medicine ,Set (psychology) ,Pandemics ,Patient Care Team ,business.industry ,SARS-CoV-2 ,Communication ,Gastroenterology ,COVID-19 ,Endoscopy ,Workforce ,030211 gastroenterology & hepatology ,business ,Coronavirus Infections ,human activities - Abstract
Background Endoscopy services have had to rapidly adapt their working practices in response to COVID-19. As recovery of endoscopy services proceeds, our workforce faces numerous challenges that can impair effective teamworking. We designed and developed a novel toolkit to support teamworking in endoscopy during the pandemic. Methods A human factors model was developed to understand the impact of COVID-19 on endoscopy teams. From this, we identified a set of key teamworking goals, which informed the development of a toolkit to support several team processes. The toolkit was refined following expert input and refinement over a 6-week period. Results The toolkit consists of four cognitive aids that can be used to support team huddles, briefings, and debriefs, alongside techniques to optimize endoscopic nontechnical skills across the patient-procedure pathway. We describe the processes that local endoscopy units can employ to implement this toolkit. Conclusion A toolkit of cognitive aids, based on human factors principles, may be useful in supporting teams, helping them adapt to working safely in the era of COVID-19.
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- 2020
24. JAG/BSG national survey of UK endoscopy services: impact of the COVID-19 pandemic and early restoration of endoscopy services
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Matthew D. Rutter, Chris Healey, Ian D. Penman, David Beaton, Jamie Catlow, Mark Coleman, Tim Shaw, Raphael Broughton, and Iosif Beintaris
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Hepatology ,Referral ,medicine.diagnostic_test ,business.industry ,Service delivery framework ,Gastroenterology ,Staffing ,Colonoscopy ,health service research ,Workload ,Endoscopy ,medicine.disease ,Vetting ,colonoscopy ,Medicine ,Medical emergency ,business ,Personal protective equipment - Abstract
IntroductionThe COVID-19 pandemic has profoundly affected UK endoscopy workload. The Joint Advisory Group on GI endoscopy and British Society of Gastroenterology issued guidelines on endoscopy service delivery changes and restoration. We surveyed UK endoscopy clinical leads to gain insights into service restoration.MethodsA Google Forms-designed survey, assessing endoscopy provision, Covid minimisation and referral pathways was circulated to all UK endoscopy leads. The survey was open between 19 and 24 May 2020.Results97 endoscopy leads completed the survey, with all UK nations and regions represented. Analysis showed 20% of endoscopy services were not providing endoscopy. Workload limitations were due to enforced interprocedural downtime (92%; with some services enforcing >1-hour downtime between procedures), social distancing (88%) and working in personal protective equipment (PPE) (87%). 91% of services reported a referral backlog (urgent median 2 months, routine median 6 months). 96% of services reported no current problems accessing PPE. Level 1/2 PPE use in colonoscopy was not uniform. 63% of services routinely swab patients for COVID-19 before endoscopy, 88% of services do not routinely swab asymptomatic staff. Comments addressed reducing endoscopy demand through vetting and changing referral criteria, the mostly commonly cited strategy being increased faecal immunochemical testing in symptomatic patients (70% of services).ConclusionThis survey demonstrates the pandemic’s profound impact on UK endoscopy. Challenges include standardising Covid-minimisation strategies and recovering staffing levels. To improve endoscopy services, there is a need to refine referral pathways, improve vetting and clarify guidance on downtime and PPE within endoscopy.
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- 2020
25. Improving safety and reducing error in endoscopy (ISREE): a survey of UK services
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Raphael Broughton, Srivathsan Ravindran, Mark Coleman, Helen Griffiths, Tim Shaw, Dimple Keen, Ara Darzi, Chris Healey, Paul Bassett, Eleanor Wood, Michael Dron, Hutan Ashrafian, John Green, and Siwan Thomas-Gibson
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Response rate (survey) ,Hepatology ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,Endoscopy ,Census ,03 medical and health sciences ,0302 clinical medicine ,Key (cryptography) ,Medicine ,030211 gastroenterology & hepatology ,Operations management ,030212 general & internal medicine ,business ,Gastrointestinal endoscopy - Abstract
BackgroundThe Joint Advisory Group on Gastrointestinal Endoscopy (JAG) ‘Improving Safety and Reducing Error in Endoscopy’ (ISREE) strategy was developed in 2018. In line with the strategy, a survey was conducted within the JAG census in 2019 to gain further insights and understanding of key safety-related areas within UK endoscopy.MethodsQuestions were developed using the ISREE strategy as a guide and adapted by key JAG stakeholders. They were incorporated into the 2019 JAG census of UK endoscopy services. Quantitative and qualitative statistical methods were employed to analyse the results.ResultsThere was a 68% response rate. There was regional variability in the provision of out-of-hours GIB services (pConclusionsThe census provides a benchmark for key safety-related characteristics of endoscopy services. These results have highlighted key areas to develop, guided by the ISREE strategy.
- Published
- 2020
26. National census of UK endoscopy services in 2019
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Tim Shaw, Chris Healey, Debbie Johnston, Paul Bassett, Hutan Ashrafian, Ara Darzi, Mark Coleman, Michael Dron, Raphael Broughton, Srivathsan Ravindran, John Green, and Siwan Thomas-Gibson
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Response rate (survey) ,medicine.medical_specialty ,Hepatology ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,Endoscopy ,Census ,Insourcing ,Family medicine ,Workforce ,Pandemic ,Medicine ,Business plan ,business ,Accreditation - Abstract
IntroductionThe 2017 Joint Advisory Group on Gastrointestinal (GI) Endoscopy (JAG) census highlighted the pressure endoscopy services were under in meeting national targets and the factors behind this. In 2019, JAG conducted a further national census of endoscopy services to understand trends in activity, workforce and waiting time targets.MethodsIn April 2019, the census was sent to all eligible JAG-registered services. Collated data were analysed through various statistical methods. A further comparative dataset was created using available submissions from the 2017 census matched to services in the current census.ResultsThere was a 68% response rate (322/471). There has been a 12%–15% increase in activity across all GI procedures with largest increases in bowel cancer screening. Fewer services are meeting waiting time targets compared with 2017, with endoscopist, nursing and physical capacity cited as the main reasons. Services are striving to improve capacity: 80% of services have an agreed business plan to meet capacity and the number using insourcing has increased from 13% to 20%. The workforce has increased, with endoscopist numbers increasing by 15%, nurses and allied health professionals by 14% and clerical staff by 30%.ConclusionsThe 2019 JAG census is the most recent and extensive survey of UK endoscopy services. There is a clear trend of increasing activity with fewer services able to meet national waiting time targets than 2 years ago. Services have increased their workforce and improved planning to stem the tide but there remains a continued pressure to deliver high quality, safe endoscopy. In light of the COVID-19 pandemic, JAG recognises that these pressures will be severely exacerbated and waiting time targets for accreditation will need adjustment and tolerance during the evolution and recovery from the pandemic.
- Published
- 2020
27. A NATIONAL SURVEY OF SAFETY ACROSS UK ENDOSCOPY SERVICES
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Hutan Ashrafian, E Wood, Raphael Broughton, Michael Dron, Srivathsan Ravindran, Siwan Thomas-Gibson, Tim Shaw, Dimple Keen, J Green, Helen Griffiths, Ara Darzi, Chris Healey, and Paul Bassett
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medicine.diagnostic_test ,business.industry ,medicine ,Medical emergency ,business ,medicine.disease ,Endoscopy - Published
- 2020
28. THE JOINT ADVISORY GROUP ON GI ENDOSCOPY (JAG) SURVEY OF UK ENDOSCOPY SERVICES: RESULTS FROM THE 2019 CENSUS
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Hutan Ashrafian, Srivathsan Ravindran, Michael Dron, Helen Griffiths, Siwan Thomas-Gibson, Raphael Broughton, Chris Healey, Ara Darzi, Tim Shaw, and J Green
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medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,General surgery ,medicine ,Gi endoscopy ,Census ,business ,Endoscopy - Published
- 2020
29. Hexagonal Boron Nitride Cavity Optomechanics
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Prasoon K. Shandilya, Johannes E. Fröch, Matthew Mitchell, David P. Lake, Sejeong Kim, Milos Toth, Bishnupada Behera, Chris Healey, Igor Aharonovich, and Paul E. Barclay
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Condensed Matter - Mesoscale and Nanoscale Physics ,Mechanical Engineering ,FOS: Physical sciences ,Bioengineering ,General Chemistry ,02 engineering and technology ,Condensed Matter Physics ,021001 nanoscience & nanotechnology ,01 natural sciences ,7. Clean energy ,010305 fluids & plasmas ,Mesoscale and Nanoscale Physics (cond-mat.mes-hall) ,0103 physical sciences ,General Materials Science ,Nanoscience & Nanotechnology ,010306 general physics ,0210 nano-technology ,Physics - Optics ,Optics (physics.optics) - Abstract
Hexagonal boron nitride (hBN) is an emerging layered material that plays a key role in a variety of two-dimensional devices, and has potential applications in nanophotonics and nanomechanics. Here, we demonstrate the first cavity optomechanical system incorporating hBN. Nanomechanical resonators consisting of hBN beams with predicted thickness between 8 nm and 51 nm were fabricated using electron beam induced etching and positioned in the optical nearfield of silicon microdisk cavities. A 160 fm/$\sqrt{\text{Hz}}$ sensitivity to the hBN nanobeam motion is demonstrated, allowing observation of thermally driven mechanical resonances with frequencies between 1 and 23 MHz, and mechanical quality factors reaching 1100 at room temperature in high vacuum. In addition, the role of air damping is studied via pressure dependent measurements. Our results constitute an important step towards realizing integrated optomechanical circuits employing hBN., Comment: Revised version
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- 2019
30. Trouble
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Chris Healey and Katrina Schlunke
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Editorial ,lcsh:NX1-820 ,lcsh:Philosophy (General) ,lcsh:Arts in general ,lcsh:B1-5802 - Abstract
Editorial by Chris Healey and Katrina Schlunke.
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- 2018
31. 'When you're it': a qualitative study exploring the rural nurse experience of managing acute mental health presentations
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Hannah Beks, Chris Healey, and Kate Schlicht
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Adult ,Emergency Medical Services ,Health (social science) ,Victoria ,Medicine (miscellaneous) ,Psychiatric Nursing ,Telehealth ,Interviews as Topic ,03 medical and health sciences ,0302 clinical medicine ,Nursing ,Humans ,030212 general & internal medicine ,Rural Nursing ,Competence (human resources) ,Qualitative Research ,Mental Disorders ,Public Health, Environmental and Occupational Health ,030208 emergency & critical care medicine ,Emergency department ,Middle Aged ,Mental health ,Acute Disease ,Female ,Rural area ,Psychology ,Emergency Service, Hospital ,Qualitative research ,Emergency nursing - Abstract
Introduction A higher proportion of chronic mental illness is reported for populations residing in inner and outer regional (IOR) areas when compared to major cities in Australia. Conversely, fewer mental health professionals work in IOR areas when compared to major cities indicating poorer access to services for rural populations. Rural emergency departments (EDs) and urgent care centres (UCCs) deliver a broad range of services. Often they are the first point of care for consumers experiencing acute mental health issues. Rural nurses working in EDs and UCCs require a diverse clinical skill set to manage complex presentations, often with limited support and resources. Developments in telehealth services have reportedly improved access for rural consumers. It is known that nurses report a lack of skills and confidence when managing mental health presentations. Despite these challenges, there is little documented regarding the experience of generalist nurses managing acute mental health presentations in rural hospitals that have limited support of community mental health teams and no onsite inpatient mental health facilities. Methods A qualitative study was conducted to explore the experience of rural nurses in managing acute mental health presentations within an emergency context. An interview guide developed from the literature was used to explore issues of experience, safety, knowledge and clinical confidence. Thirteen rural generalist nurses from one rural emergency department and two rural UCCs located in south-west Victoria participated in a semi-structured interview. Interviews were audio-recorded and transcribed verbatim. Transcriptions were thematically analysed by applying an inductive descriptive approach. Results The majority of participants were experienced generalist registered nurses with no formal qualifications in mental health. Two participants had some clinical experience in mental health and drug and alcohol. Themes elicited from data analysis and discussion between the researchers were (1) 'we are the frontline', (2) 'doing our best to provide care', (3) 'complexities of navigating the system', and (4) 'thinking about change'. Findings indicated that rural generalist nurses deliver the majority of care to mental health consumers in EDs and UCCs. Local mental health clinicians and emergency service providers offer limited support, with a reliance on telephone triage for after-hours assessment. Multiple challenges were cited including coordinating the transfer of consumers to inpatient facilities and feeling inadequately supported. Irrespective of these challenges, nurses reported delivering the best possible care to consumers despite reporting a lack of knowledge and skills. Recommendations for improving the delivery of care included increasing access to emergency mental health training and receiving more support from local mental health teams. The need for more rural mental health facilities was also discussed. Conclusions The findings from this study suggest generalist nurses are the frontline providers of care for mental health consumers in rural EDs and UCCs. Nurses feel ill-equipped for assessing and managing mental health presentations, relying heavily on local mental health teams and telephone triage who provide limited onsite support. The need to support nurses through training and mentoring relationships with community mental health teams is highlighted by this study in conjunction with improving the delivery of mental health services in rural areas.
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- 2018
32. Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score
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Marco Carbone, Alessandra Nardi, Steve Flack, Guido Carpino, Nikoletta Varvaropoulou, Caius Gavrila, Ann Spicer, Jonathan Badrock, Francesca Bernuzzi, Vincenzo Cardinale, Holly F Ainsworth, Michael A Heneghan, Douglas Thorburn, Andrew Bathgate, Rebecca Jones, James M Neuberger, Pier Maria Battezzati, Massimo Zuin, Simon Taylor-Robinson, Maria F Donato, John Kirby, Robert Mitchell-Thain, Annarosa Floreani, Fotios Sampaziotis, Luigi Muratori, Domenico Alvaro, Marco Marzioni, Luca Miele, Fabio Marra, Edoardo Giannini, Eugenio Gaudio, Vincenzo Ronca, Giulia Bonato, Laura Cristoferi, Federica Malinverno, Alessio Gerussi, Deborah D Stocken, Heather J Cordell, Gideon M Hirschfield, Graeme J Alexander, Richard N Sandford, David E Jones, Pietro Invernizzi, George F Mells, Caradog Thomas, Meshbah Rahman, Tom Yapp, Chin Lye Ch'ng, Melanie Harrison, Richard Sturgess, Roman Galaska, Chris Healey, Jessica Whiteman, Marek Czaijkowski, Catherine Gray, Anton Gunasekera, Pranab Gyawli, Purushothaman Premchand, Steven Mann, Keith Elliott, Kapil Kapur, Alan Watson, Graham Foster, Paul Trembling, Javaid Subhani, Rory Harvey, Roger McCorry, Carolyn Adgey, Lucie Hobson, Caroline Mulvaney-Jones, Richard Evans, Thiriloganathan Mathialahan, David Ramanaden, Jaber Gasem, Greta Van Duyvenvoorde, Christopher Shorrock, Katie Seward, Paul Southern, Jeremy Tibble, Ruth Penn, David Gorard, Jane Maiden, Rose Damant, Altaf Palegwala, Susan Jones, Graeme Alexander, George Mells, Richard Sandford, Sunil Dolwani, Martin Prince, Valeria Silvestre, Matthew Foxton, Eleanor Dungca, Harriet Mitchison, Natalie Wheatley, Ian Gooding, Helen Doyle, Mazn Karmo, Melanie Kent, Sushma Saksena, Delyth Braim, Minesh Patel, Susan Lord, Roland Ede, Alison Paton, Andrew Austin, Nicola Lancaster, Joanna Sayer, Andrew Gibbins, Karen Hogben, Chris Hovell, Neil Fisher, Martyn Carter, Konrad Koss, Janine Musselwhite, Florin Muscariu, Andrzej Piotreowicz, Alexandra McKay, Charles Grimley, David Neal, Lai Ting Tan, Guan Lim, Jacqueline Brighton, Carole Foale, Aftab Ala, Athar Saeed, Kerry Flahive, Gordon Wood, Paula Townshend, Chris Ford, Jonathan Brown, Jean Kordula, Jane Bowles, Mark Wilkinson, Caroline Palmer, John Ramage, Harriet Gordon, James Featherstone, Jo Ridpath, Theodore Ngatchu, Sass Levi, Syed Shaukat, Joy Sadeghian, Ray Shidrawi, Bronwen Williams, George Abouda, Sarah Jones, Claire Duggan, Abigail Hynes, Mark Narain, Ian Rees, Imroz Salam, Mary Crossey, Ashley Brown, Carolyn MacNicol, Simon Williams, Elva Wilhelmsen, Paul Banim, Parizade Raymode, Andrew Chilton, Debasish Das, Hye-Jeong Lee, Howard Curtis, Michael Heneghan, Markus Gess, Emma Durant, IM Drake, Rebecca Bishop, Mervyn Davies, Mark Aldersley, Noma Ncube, Alistair McNair, Raj Srirajaskanthan, Sambit Sen, Rebecca Casey, George Bird, Mike Mendall, Caroline Cowley, Adrian Barnardo, Paul Kitchen, Kevin Yoong, Kelly Amore, Dawn Sirdefield, Jacky Orpe, Ray Mathew, George MacFaul, Aruna Wrigth, Amir Shah, Chris Evans, Janie Keggans, Bridget Bird, Gwen Baxter, Subrata Saha, Katharine Pollock, Maggie Hughes, Peter Bramley, Emma Grieve, Karin Young, Andrew Fraser, Ashis Mukhopadhya, Kate Ocker, Peter Mills, Francis Hines, Chris Shallcross, Joy Wilkins, Leonie Grellier, Stewart Campbell, Kirsty Martin, Caron Innes, Alan Shepherd, Simon Rushbrook, Talal Valliani, Robert Przemioslo, Helen Fairlamb, Chris Macdonald, Anne Eastick, Jane Metcalf, Elizabeth Tanqueray, Udi Shmueli, Becky Holbrook, Andrew Davis, Julie Browning, Asifabbas Naqvi, Kirsten Walker, Tom Lee, Juliette Verheyden, Susan Slininger, Stephen D Ryder, Roger Chapman, Jane Collier, Denise O'Donnell, Lizzie Stafford, Kate Williamson, Linda Kent, Howard Klass, Mary Ninkovic, Linda March, Matthew Cramp, Diane Simpson, Christine Dickson, Nicholas Sharer, Maria Hayes, Patrick Goggin, Mary Quinne, Sallyanne Pearson, Barbara Hoeroldt, Linda Jones, Alice Wright, Jonathan Booth, Alison Loftus, George Lipscomb, Hannah Dewhurst, Emma Gunter, Earl Williams, Anna Fouracres, Liz Farrington, Lyn Graves, Hyder Hussaini, Bill Stableforth, Suzie Marriott, Reuben Ayres, Marina Leoni, Andrew Burroughs, Eileen Marshall, David Tyrer, Kate Martin, Martin Lombard, Imran Patanwala, Lola Dali-Kemmery, Victoria Lambourne, Julia Maltby, Samir Vyas, Julie Colley, Bal Shinder, Saket Singhal, Jayne Jones, Marisa Mills, Dermot Gleeson, Mandy Carnahan, Jeff Butterworth, Kerenza Boulton, Natalie Taylor, Keith George, Tim Harding, Julie Tregonning, Andrew Douglass, Carly Brown, Gayle Clifford, Simon Panter, Denise Gocher, Jeremy Shearman, Gary Bray, Maria Hamilton, Graham Butcher, Daniel Forton, John Mclindon, Janette Curtis, Debashis Das, Tracey Shewan, Matthew Cowan, Gregory Whatley, Mariam Nasseri, Bob Grover, Nurani Sivaramakrishnan, Samantha Ducker, Kathryn Houghton, David Jones, Laura Griffiths, Sherill Tripoli, Maxton Pitcher, Ervin Shpuza, Nikki White, Deb Ghosh, Andrew Douds, Marie Green, Matthew Brookes, Lourdes Cumlat, Voi Shim Wong, Karen Warner, Kimberley Netherton, Adtya Mandal, Snjiv Jain, Hemant Gupta, Pradeep Sanghi, Steve Pereira, James Neuberger, Bridget Gunson, Gideon Hirschfield, Reina Teegan Lim, Susan Gallagher, Darren Clement, Alison Brind, Gill Watts, Mcdonald Mupudzi, Mark Wright, Jane Gitahi, Fiona Gordon, Denis Gocher, Esther Unitt, Hilary Pateman, Sally Batham, Toby Delahooke, Allister Grant, Jill Conder, Andrew Higham, Mark Cox, Lynn O'Donohoe, Lynn Currie, Alistair King, Metod Oblak, Carole Collins, Simon Whalley, Marie Quinn, Yolanda Baird, Isobel Amey, Jocelyn Fraser, Andy Li, Donna Cotterill, Andrew Bell, Amit Singhal, Ian Gee, Sandra Greer, Yeng Ang, Rupert Ransford, Joanna Allison, James Gotto, Simon Dyer, Helen Sweeting, Charles Millson, Giancarlo Labbadia, Maria Consiglia Bragazzi, Pietro Andreone, Francesco Azzaroli, Andrea Galli, Mirko Tarocchi, Antonio Gasbarrini, Antonio Grieco, Giuseppe Marrone, Maria Francesca Donato, Luca Valenti, Luca Maroni, Cristina Rigamonti, Antonino Picciotto, Carbone, M, Nardi, A, Flack, S, Carpino, G, Varvaropoulou, N, Gavrila, C, Spicer, A, Badrock, J, Bernuzzi, F, Cardinale, V, Ainsworth, H, Heneghan, M, Thorburn, D, Bathgate, A, Jones, R, Neuberger, J, Battezzati, P, Zuin, M, Taylor-Robinson, S, Donato, M, Kirby, J, Mitchell-Thain, R, Floreani, A, Sampaziotis, F, Muratori, L, Alvaro, D, Marzioni, M, Miele, L, Marra, F, Giannini, E, Gaudio, E, Ronca, V, Bonato, G, Cristoferi, L, Malinverno, F, Gerussi, A, Stocken, D, Cordell, H, Hirschfield, G, Alexander, G, Sandford, R, Jones, D, Invernizzi, P, Mells, G, Thomas, C, Rahman, M, Yapp, T, Lye Ch'ng, C, Harrison, M, Sturgess, R, Galaska, R, Healey, C, Whiteman, J, Czaijkowski, M, Gray, C, Gunasekera, A, Gyawli, P, Premchand, P, Mann, S, Elliott, K, Kapur, K, Watson, A, Foster, G, Trembling, P, Subhani, J, Harvey, R, Mccorry, R, Adgey, C, Hobson, L, Mulvaney-Jones, C, Evans, R, Mathialahan, T, Ramanaden, D, Gasem, J, Van Duyvenvoorde, G, Shorrock, C, Seward, K, Southern, P, Tibble, J, Penn, R, Gorard, D, Maiden, J, Damant, R, Palegwala, A, Jones, S, Dolwani, S, Prince, M, Silvestre, V, Foxton, M, Dungca, E, Mitchison, H, Wheatley, N, Gooding, I, Doyle, H, Karmo, M, Kent, M, Saksena, S, Braim, D, Patel, M, Lord, S, Ede, R, Paton, A, Austin, A, Lancaster, N, Sayer, J, Gibbins, A, Hogben, K, Hovell, C, Fisher, N, Carter, M, Koss, K, Musselwhite, J, Muscariu, F, Piotreowicz, A, Mckay, A, Grimley, C, Neal, D, Ting Tan, L, Lim, G, Brighton, J, Foale, C, Ala, A, Saeed, A, Flahive, K, Wood, G, Townshend, P, Ford, C, Brown, J, Kordula, J, Bowles, J, Wilkinson, M, Palmer, C, Ramage, J, Gordon, H, Featherstone, J, Ridpath, J, Ngatchu, T, Levi, S, Shaukat, S, Sadeghian, J, Shidrawi, R, Williams, B, Abouda, G, Duggan, C, Hynes, A, Narain, M, Rees, I, Salam, I, Crossey, M, Brown, A, Macnicol, C, Williams, S, Wilhelmsen, E, Banim, P, Raymode, P, Chilton, A, Das, D, Lee, H, Curtis, H, Gess, M, Durant, E, Drake, I, Bishop, R, Davies, M, Aldersley, M, Ncube, N, Mcnair, A, Srirajaskanthan, R, Sen, S, Casey, R, Bird, G, Mendall, M, Cowley, C, Barnardo, A, Kitchen, P, Yoong, K, Amore, K, Sirdefield, D, Orpe, J, Mathew, R, Macfaul, G, Wrigth, A, Shah, A, Evans, C, Keggans, J, Bird, B, Baxter, G, Saha, S, Pollock, K, Hughes, M, Bramley, P, Grieve, E, Young, K, Fraser, A, Mukhopadhya, A, Ocker, K, Mills, P, Hines, F, Shallcross, C, Wilkins, J, Grellier, L, Campbell, S, Martin, K, Innes, C, Shepherd, A, Rushbrook, S, Valliani, T, Przemioslo, R, Fairlamb, H, Macdonald, C, Eastick, A, Metcalf, J, Tanqueray, E, Shmueli, U, Holbrook, B, Davis, A, Browning, J, Naqvi, A, Walker, K, Lee, T, Verheyden, J, Slininger, S, Ryder, S, Chapman, R, Collier, J, O'Donnell, D, Stafford, L, Williamson, K, Kent, L, Klass, H, Ninkovic, M, March, L, Cramp, M, Simpson, D, Dickson, C, Sharer, N, Hayes, M, Goggin, P, Quinne, M, Pearson, S, Hoeroldt, B, Jones, L, Wright, A, Booth, J, Loftus, A, Lipscomb, G, Dewhurst, H, Gunter, E, Williams, E, Fouracres, A, Farrington, L, Graves, L, Hussaini, H, Stableforth, B, Marriott, S, Ayres, R, Leoni, M, Burroughs, A, Marshall, E, Tyrer, D, Lombard, M, Patanwala, I, Dali-Kemmery, L, Lambourne, V, Maltby, J, Vyas, S, Colley, J, Shinder, B, Singhal, S, Jones, J, Mills, M, Gleeson, D, Carnahan, M, Butterworth, J, Boulton, K, Taylor, N, George, K, Harding, T, Tregonning, J, Douglass, A, Brown, C, Clifford, G, Panter, S, Gocher, D, Shearman, J, Bray, G, Hamilton, M, Butcher, G, Forton, D, Mclindon, J, Curtis, J, Shewan, T, Cowan, M, Whatley, G, Nasseri, M, Grover, B, Sivaramakrishnan, N, Ducker, S, Houghton, K, Griffiths, L, Tripoli, S, Pitcher, M, Shpuza, E, White, N, Ghosh, D, Douds, A, Green, M, Brookes, M, Cumlat, L, Wong, V, Warner, K, Netherton, K, Mandal, A, Jain, S, Gupta, H, Sanghi, P, Pereira, S, Gunson, B, Lim, R, Gallagher, S, Clement, D, Brind, A, Watts, G, Mupudzi, M, Wright, M, Gitahi, J, Gordon, F, Unitt, E, Pateman, H, Batham, S, Delahooke, T, Grant, A, Conder, J, Higham, A, Cox, M, O'Donohoe, L, Currie, L, King, A, Oblak, M, Collins, C, Whalley, S, Quinn, M, Baird, Y, Amey, I, Fraser, J, Li, A, Cotterill, D, Bell, A, Singhal, A, Gee, I, Greer, S, Ang, Y, Ransford, R, Allison, J, Gotto, J, Dyer, S, Sweeting, H, Millson, C, Labbadia, G, Bragazzi, M, Andreone, P, Azzaroli, F, Galli, A, Tarocchi, M, Gasbarrini, A, Grieco, A, Marrone, G, Valenti, L, Maroni, L, Rigamonti, C, Picciotto, A, Sampaziotis, Fotios [0000-0003-0812-7586], Sandford, Richard [0000-0002-7437-0560], Apollo - University of Cambridge Repository, Carbone, Marco, Nardi, Alessandra, Flack, Steve, Carpino, Guido, Varvaropoulou, Nikoletta, Gavrila, Caiu, Spicer, Ann, Badrock, Jonathan, Bernuzzi, Francesca, Cardinale, Vincenzo, Ainsworth, Holly F, Heneghan, Michael A, Thorburn, Dougla, Bathgate, Andrew, Jones, Rebecca, Neuberger, James M, Battezzati, Pier Maria, Zuin, Massimo, Taylor-Robinson, Simon, Donato, Maria F, Kirby, John, Mitchell-Thain, Robert, Floreani, Annarosa, Sampaziotis, Fotio, Muratori, Luigi, Alvaro, Domenico, Marzioni, Marco, Miele, Luca, Marra, Fabio, Giannini, Edoardo, Gaudio, Eugenio, Ronca, Vincenzo, Bonato, Giulia, Cristoferi, Laura, Malinverno, Federica, Gerussi, Alessio, Stocken, Deborah D, Cordell, Heather J, Hirschfield, Gideon M, Alexander, Graeme J, Sandford, Richard N, Jones, David E, Invernizzi, Pietro, Mells, George F, Thomas, Caradog, Rahman, Meshbah, Yapp, Tom, Lye Ch'ng, Chin, Harrison, Melanie, Sturgess, Richard, Galaska, Roman, Healey, Chri, Whiteman, Jessica, Czaijkowski, Marek, Gray, Catherine, Gunasekera, Anton, Gyawli, Pranab, Premchand, Purushothaman, Mann, Steven, Elliott, Keith, Kapur, Kapil, Watson, Alan, Foster, Graham, Trembling, Paul, Subhani, Javaid, Harvey, Rory, McCorry, Roger, Adgey, Carolyn, Hobson, Lucie, Mulvaney-Jones, Caroline, Evans, Richard, Mathialahan, Thiriloganathan, Ramanaden, David, Gasem, Jaber, Van Duyvenvoorde, Greta, Shorrock, Christopher, Seward, Katie, Southern, Paul, Tibble, Jeremy, Penn, Ruth, Gorard, David, Maiden, Jane, Damant, Rose, Palegwala, Altaf, Jones, Susan, Alexander, Graeme, Mells, George, Sandford, Richard, Dolwani, Sunil, Prince, Martin, Silvestre, Valeria, Foxton, Matthew, Dungca, Eleanor, Mitchison, Harriet, Wheatley, Natalie, Gooding, Ian, Doyle, Helen, Karmo, Mazn, Kent, Melanie, Saksena, Sushma, Braim, Delyth, Patel, Minesh, Lord, Susan, Ede, Roland, Paton, Alison, Austin, Andrew, Lancaster, Nicola, Sayer, Joanna, Gibbins, Andrew, Hogben, Karen, Hovell, Chri, Fisher, Neil, Carter, Martyn, Koss, Konrad, Musselwhite, Janine, Muscariu, Florin, Piotreowicz, Andrzej, McKay, Alexandra, Grimley, Charle, Neal, David, Ting Tan, Lai, Lim, Guan, Brighton, Jacqueline, Foale, Carole, Ala, Aftab, Saeed, Athar, Flahive, Kerry, Wood, Gordon, Townshend, Paula, Ford, Chri, Brown, Jonathan, Kordula, Jean, Bowles, Jane, Wilkinson, Mark, Palmer, Caroline, Ramage, John, Gordon, Harriet, Featherstone, Jame, Ridpath, Jo, Ngatchu, Theodore, Levi, Sa, Shaukat, Syed, Sadeghian, Joy, Shidrawi, Ray, Williams, Bronwen, Abouda, George, Jones, Sarah, Duggan, Claire, Hynes, Abigail, Narain, Mark, Rees, Ian, Salam, Imroz, Crossey, Mary, Brown, Ashley, MacNicol, Carolyn, Williams, Simon, Wilhelmsen, Elva, Banim, Paul, Raymode, Parizade, Chilton, Andrew, Das, Debasish, Lee, Hye-Jeong, Curtis, Howard, Heneghan, Michael, Gess, Marku, Durant, Emma, Drake, I.M., Bishop, Rebecca, Davies, Mervyn, Aldersley, Mark, Ncube, Noma, McNair, Alistair, Srirajaskanthan, Raj, Sen, Sambit, Casey, Rebecca, Bird, George, Mendall, Mike, Cowley, Caroline, Barnardo, Adrian, Kitchen, Paul, Yoong, Kevin, Amore, Kelly, Sirdefield, Dawn, Orpe, Jacky, Mathew, Ray, MacFaul, George, Wrigth, Aruna, Shah, Amir, Evans, Chri, Keggans, Janie, Bird, Bridget, Baxter, Gwen, Saha, Subrata, Pollock, Katharine, Hughes, Maggie, Bramley, Peter, Grieve, Emma, Young, Karin, Fraser, Andrew, Mukhopadhya, Ashi, Ocker, Kate, Mills, Peter, Hines, Franci, Shallcross, Chri, Wilkins, Joy, Grellier, Leonie, Campbell, Stewart, Martin, Kirsty, Innes, Caron, Shepherd, Alan, Rushbrook, Simon, Valliani, Talal, Przemioslo, Robert, Fairlamb, Helen, Macdonald, Chri, Eastick, Anne, Metcalf, Jane, Tanqueray, Elizabeth, Shmueli, Udi, Holbrook, Becky, Davis, Andrew, Browning, Julie, Naqvi, Asifabba, Walker, Kirsten, Lee, Tom, Verheyden, Juliette, Slininger, Susan, Ryder, Stephen D, Chapman, Roger, Collier, Jane, O'Donnell, Denise, Stafford, Lizzie, Williamson, Kate, Kent, Linda, Klass, Howard, Ninkovic, Mary, March, Linda, Cramp, Matthew, Simpson, Diane, Dickson, Christine, Sharer, Nichola, Hayes, Maria, Goggin, Patrick, Quinne, Mary, Pearson, Sallyanne, Hoeroldt, Barbara, Jones, Linda, Wright, Alice, Booth, Jonathan, Loftus, Alison, Lipscomb, George, Dewhurst, Hannah, Gunter, Emma, Williams, Earl, Fouracres, Anna, Farrington, Liz, Graves, Lyn, Hussaini, Hyder, Stableforth, Bill, Marriott, Suzie, Ayres, Reuben, Leoni, Marina, Burroughs, Andrew, Marshall, Eileen, Tyrer, David, Martin, Kate, Lombard, Martin, Patanwala, Imran, Dali-Kemmery, Lola, Lambourne, Victoria, Maltby, Julia, Vyas, Samir, Colley, Julie, Shinder, Bal, Singhal, Saket, Jones, Jayne, Mills, Marisa, Gleeson, Dermot, Carnahan, Mandy, Butterworth, Jeff, Boulton, Kerenza, Taylor, Natalie, George, Keith, Harding, Tim, Tregonning, Julie, Douglass, Andrew, Brown, Carly, Clifford, Gayle, Panter, Simon, Gocher, Denise, Shearman, Jeremy, Bray, Gary, Hamilton, Maria, Butcher, Graham, Forton, Daniel, Mclindon, John, Curtis, Janette, Das, Debashi, Shewan, Tracey, Cowan, Matthew, Whatley, Gregory, Nasseri, Mariam, Grover, Bob, Sivaramakrishnan, Nurani, Ducker, Samantha, Houghton, Kathryn, Jones, David, Griffiths, Laura, Tripoli, Sherill, Pitcher, Maxton, Shpuza, Ervin, White, Nikki, Ghosh, Deb, Douds, Andrew, Green, Marie, Brookes, Matthew, Cumlat, Lourde, Wong, Voi Shim, Warner, Karen, Netherton, Kimberley, Mandal, Adtya, Jain, Snjiv, Gupta, Hemant, Sanghi, Pradeep, Pereira, Steve, Neuberger, Jame, Gunson, Bridget, Hirschfield, Gideon, Lim, Reina Teegan, Gallagher, Susan, Clement, Darren, Brind, Alison, Watts, Gill, Mupudzi, Mcdonald, Wright, Mark, Gitahi, Jane, Gordon, Fiona, Gocher, Deni, Unitt, Esther, Pateman, Hilary, Batham, Sally, Delahooke, Toby, Grant, Allister, Conder, Jill, Higham, Andrew, Cox, Mark, O'Donohoe, Lynn, Currie, Lynn, King, Alistair, Oblak, Metod, Collins, Carole, Whalley, Simon, Quinn, Marie, Baird, Yolanda, Amey, Isobel, Fraser, Jocelyn, Li, Andy, Cotterill, Donna, Bell, Andrew, Singhal, Amit, Gee, Ian, Greer, Sandra, Ang, Yeng, Ransford, Rupert, Allison, Joanna, Gotto, Jame, Dyer, Simon, Sweeting, Helen, Millson, Charle, Labbadia, Giancarlo, Bragazzi, Maria Consiglia, Andreone, Pietro, Azzaroli, Francesco, Galli, Andrea, Tarocchi, Mirko, Gasbarrini, Antonio, Grieco, Antonio, Marrone, Giuseppe, Donato, Maria Francesca, Valenti, Luca, Maroni, Luca, Rigamonti, Cristina, Picciotto, Antonino, and Medical Research Council (MRC)
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Male ,Cholagogues and Choleretics ,Cirrhosis ,medicine.medical_treatment ,PROGRESSION ,Liver transplantation ,PHENOTYPE ,Gastroenterology ,UDCA ,0302 clinical medicine ,Primary biliary cirrhosis ,Risk Factors ,Medicine ,Age of Onset ,CIRRHOSIS ,TREE ,OUTCOMES ,Settore MED/12 - Gastroenterologia ,medicine.diagnostic_test ,Liver Cirrhosis, Biliary ,Ursodeoxycholic Acid ,Area under the curve ,URSODIOL ,Middle Aged ,Ursodeoxycholic acid ,Treatment Outcome ,Primary biliary cholangitis ,ursodeoxycholic acid ,030220 oncology & carcinogenesis ,Liver biopsy ,Area Under Curve ,030211 gastroenterology & hepatology ,Female ,Life Sciences & Biomedicine ,medicine.drug ,medicine.medical_specialty ,CONTROLLED-TRIAL ,Hepatology ,Decision Support Techniques ,Time-to-Treatment ,Biliary injury ,03 medical and health sciences ,Internal medicine ,Humans ,Transaminases ,Science & Technology ,Gastroenterology & Hepatology ,Italian PBC Study Group and the UK–PBC Consortium ,business.industry ,Bilirubin ,medicine.disease ,Alkaline Phosphatase ,ROC Curve ,CELLS ,Linear Models ,business - Abstract
Background: Treatment guidelines recommend a stepwise approach to primary biliary cholangitis: all patients begin treatment with ursodeoxycholic acid (UDCA) monotherapy and those with an inadequate biochemical response after 12 months are subsequently considered for second-line therapies. However, as a result, patients at the highest risk can wait the longest for effective treatment. We determined whether UDCA response can be accurately predicted using pretreatment clinical parameters. Methods: We did logistic regression analysis of pretreatment variables in a discovery cohort of patients in the UK with primary biliary cholangitis to derive the best-fitting model of UDCA response, defined as alkaline phosphatase less than 1·67 times the upper limit of normal (ULN), measured after 12 months of treatment with UDCA. We validated the model in an external cohort of patients with primary biliary cholangitis and treated with UDCA in Italy. Additionally, we assessed correlations between model predictions and key histological features, such as biliary injury and fibrosis, on liver biopsy samples. Findings: 2703 participants diagnosed with primary biliary cholangitis between Jan 1, 1998, and May 31, 2015, were included in the UK-PBC cohort for derivation of the model. The following pretreatment parameters were associated with lower probability of UDCA response: higher alkaline phosphatase concentration (p
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- 2018
33. Design and experimental demonstration of optomechanical paddle nanocavities
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Paul E. Barclay, Matthew Mitchell, Chris Healey, Marcelo Wu, Aaron C. Hryciw, Behzad Khanaliloo, and Hamidreza Kaviani
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Coupling ,Materials science ,Fabrication ,Physics and Astronomy (miscellaneous) ,Silicon ,business.industry ,FOS: Physical sciences ,chemistry.chemical_element ,02 engineering and technology ,021001 nanoscience & nanotechnology ,01 natural sciences ,Nanomechanical resonator ,Quality (physics) ,chemistry ,0103 physical sciences ,Paddle ,Optoelectronics ,010306 general physics ,0210 nano-technology ,business ,Optomechanics ,Optics (physics.optics) ,Physics - Optics ,Photonic crystal - Abstract
We present the design, fabrication and initial characterization of a paddle nanocavity consisting of a suspended sub-picogram nanomechanical resonator optomechanically coupled to a photonic crystal nanocavity. The optical and mechanical properties of the paddle nanocavity can be systematically designed and optimized, and key characteristics including mechanical frequency easily tailored. Measurements under ambient conditions of a silicon paddle nanocavity demonstrate an optical mode with quality factor $Q_o$ ~ 6000 near 1550 nm, and optomechanical coupling to several mechanical resonances with frequencies $\omega_m/2\pi$ ~ 12-64 MHz, effective masses $m_\text{eff}$ ~ 350-650 fg, and mechanical quality factors $Q_m$ ~ 44-327. Paddle nanocavities are promising for optomechanical sensing and nonlinear optomechanics experiments., Comment: 5 pages, 4 figures
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- 2015
34. Nonlinear optomechanical paddle nanocavities
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Hamidreza Kaviani, Aaron C. Hryciw, Chris Healey, Marcelo Wu, and Paul E. Barclay
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Quantum optics ,Coupling ,Physics ,business.industry ,Phonon ,Shot noise ,Nanophotonics ,Physics::Optics ,Optoelectronics ,Nonlinear optics ,Optical field ,business ,Optomechanics - Abstract
Nonlinear cavity optomechanics is a promising platform for realizing experiments which reveal the quantum properties of nanomechanical structures. Here we introduce an optomechanical system combining strong nonlinear optomechanical coupling, low mass and large optical mode spacing. This nanoscale “paddle nanocavity” supports mechanical resonances with hundreds of fg mass which couple nonlinearly to optical modes with a single photon quadratic optomechanical coupling rate that is four orders of magnitude higher than competing systems. This coupling relies on strong interactions between the nanocavity optical field and mechanical excitations in a structure whose optical mode spectrum is highly non-degenerate. Nonlinear optomechanical readout of thermally driven motion in these devices should be observable for temperatures above 50 mK, and measurement of phonon shot noise is achievable. This work shows that strong nonlinear effects can be realized without relying on coupling between nearly degenerate optical modes, thus avoiding parasitic linear coupling present in two mode systems.
- Published
- 2015
35. Nonlinear optomechanical paddle nanocavities
- Author
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Aaron C. Hryciw, Chris Healey, Marcelo Wu, Roohollah Ghobadi, Hamidreza Kaviani, and Paul E. Barclay
- Subjects
Phonon ,FOS: Physical sciences ,Physics::Optics ,02 engineering and technology ,01 natural sciences ,Mesoscale and Nanoscale Physics (cond-mat.mes-hall) ,0103 physical sciences ,010306 general physics ,Optomechanics ,Photonic crystal ,Coupling ,Physics ,Quantum Physics ,Condensed Matter - Mesoscale and Nanoscale Physics ,business.industry ,Shot noise ,021001 nanoscience & nanotechnology ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,Nonlinear system ,Optoelectronics ,Whispering-gallery wave ,Quantum Physics (quant-ph) ,0210 nano-technology ,business ,Coupling coefficient of resonators ,Optics (physics.optics) ,Physics - Optics - Abstract
Nonlinear optomechanical coupling is the basis for many potential future experiments in quantum optomechanics (e.g., quantum non-demolition measurements, preparation of non-classical states), which to date have been difficult to realize due to small non-linearity in typical optomechanical devices. Here we introduce an optomechanical system combining strong nonlinear optomechanical coupling, low mass and large optical mode spacing. This nanoscale "paddle nanocavity" supports mechanical resonances with hundreds of fg mass which couple nonlinearly to optical modes with a quadratic optomechanical coupling coefficient $g^{(2)} > 2\pi\times400$ MHz/nm$^2$, and a two phonon to single photon optomechanical coupling rate $\Delta \omega_0 > 2\pi\times 16$ Hz. This coupling relies on strong phonon-photon interactions in a structure whose optical mode spectrum is highly non--degenerate. Nonlinear optomechanical readout of thermally driven motion in these devices should be observable for T $> 50 $ mK, and measurement of phonon shot noise is achievable. This shows that strong nonlinear effects can be realized without relying on coupling between nearly degenerate optical modes, thus avoiding parasitic linear coupling present in two mode systems., Comment: 8 pages, 5 figures
- Published
- 2014
36. Pharmacy-led switches of 5-ASA: impact on secondary care
- Author
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John O'Malley and Chris Healey
- Subjects
medicine.medical_specialty ,Hepatology ,business.industry ,Counterintuitive ,Gastroenterology ,Pharmacy ,Primary care ,Secondary care ,Health services ,Nursing ,Family medicine ,Active disease ,Medicine ,business ,Adverse effect ,Limited resources ,Colorectal - Abstract
Cost containment in prescribing budgets is, and always will be, a key priority in any health service with limited resources. Therefore, a number of primary care trusts (PCT) have recently initiated pharmacy-led switches of 5-aminosalicylic acids (5-ASAs), with the intention of reducing prescribing budgets. However, this has generated considerable controversy among gastroenterologists, as there is concern that the clinical consequences of such programmes have not been adequately explored. PCTs are currently under no obligation to consult secondary care prior to initiating pharmacy-led switches. In a secondary care-led condition such as inflammatory bowel disease (IBD), this seems highly counterintuitive. If gastroenterologists were to be consulted, how would we respond, and what could we contribute? This article examines the clinical consequences of PCT-initiated switch programmes in IBD, and the knock-on effects on patients and the secondary care gastroenterology community. For a switch programme to be justified, the financial benefits it imparts must be balanced against its clinical effects. Here, we consider what the clinical effects of a 5-ASA switch might be. Many gastroenterologists express concern over such programmes, but is there evidence for a detrimental effect, and what is the experience that exists among the secondary care community to inform our approach? Many gastroenterology specialists have already encountered pharmacy-led switches firsthand, and some of their experiences provide immediate cause for concern. Although anecdotal, reports abound that 5-ASA switches have been followed by flares of active disease and other adverse effects in a worrying number of patients. For example, in one recent pharmacy-led switch programme, a patient showed a significant drop in his white blood cell count after his 5-ASA was changed, and another two patients experienced bouts of diarrhoea. In a particularly worrying case, a young woman who was very concerned about her 5-ASA being switched was subsequently admitted with an episode …
- Published
- 2012
37. Dissipative and Dispersive Optomechanics in a Nanocavity Torque Sensor
- Author
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Chris Healey, Aaron C. Hryciw, Marcelo Wu, John P. Davis, Harishankar Jayakumar, Mark R. Freeman, Paul E. Barclay, and David P. Lake
- Subjects
Detection sensitivity ,genetic structures ,QC1-999 ,General Physics and Astronomy ,Physics::Optics ,FOS: Physical sciences ,Measurements of ,02 engineering and technology ,Coupling mechanism ,7. Clean energy ,01 natural sciences ,Acceleration ,Optics ,0103 physical sciences ,Mesoscale and Nanoscale Physics (cond-mat.mes-hall) ,Torque sensor ,Torque ,Dispersion (waves) ,Sensitivity (control systems) ,010306 general physics ,Optomechanics ,Physics ,Quantum Physics ,Wavelength response ,Condensed Matter - Mesoscale and Nanoscale Physics ,business.industry ,Dissipative coupling ,021001 nanoscience & nanotechnology ,eye diseases ,Magnetic field ,Dissipative system ,Physics::Accelerator Physics ,sense organs ,Ambient conditions ,Limited torques ,Mechanical resonance ,0210 nano-technology ,business ,Quantum Physics (quant-ph) ,Physics - Optics ,Optics (physics.optics) - Abstract
Dissipative and dispersive optomechanical couplings are experimentally observed in a photonic crystal split-beam nanocavity optimized for detecting nanoscale sources of torque. Dissipative coupling of up to approximately $500$ MHz/nm and dispersive coupling of $2$ GHz/nm enable measurements of sub-pg torsional and cantilever-like mechanical resonances with a thermally-limited torque detection sensitivity of 1.2$\times 10^{-20} \text{N} \, \text{m}/\sqrt{\text{Hz}}$ in ambient conditions and 1.3$\times 10^{-21} \text{N} \, \text{m}/\sqrt{\text{Hz}}$ in low vacuum. Interference between optomechanical coupling mechanisms is observed to enhance detection sensitivity and generate a mechanical-mode-dependent optomechanical wavelength response., Comment: 11 pages, 6 figures
- Published
- 2014
- Full Text
- View/download PDF
38. Optomechanical Nanostructures via Scalable Fabrication in Single-Crystal Diamond
- Author
-
Paul E. Barclay, Aaron C. Hryciw, Harishankar Jayakumar, Behzad Khanaliloo, and Chris Healey
- Subjects
Nanostructure ,Fabrication ,Materials science ,Single crystal diamond ,Scalability ,engineering ,Diamond ,Nanotechnology ,Fiber ,engineering.material ,Electron-beam lithography ,Optomechanics - Abstract
We demonstrate a scalable process flow to fabricate three-dimensional free-standing devices from bulk single-crystal diamond. Using a dimpled fiber taper, we couple selectively to four mechanical modes of a nanobeam to measure its optomechanical response.
- Published
- 2014
39. Nanoscale optomechanical sensors: Split-beam photonic crystal nanocavities
- Author
-
Paul E. Barclay, Aaron C. Hryciw, Chris Healey, Behzad Khanaliloo, and Marcelo Wu
- Subjects
Optimization ,Materials science ,Cantilever ,Silicon ,Numerical models ,Mechanical displacements ,Nanophotonics ,Opto-mechanical sensors ,chemistry.chemical_element ,Nanoscale cantilevers ,Optoelectronic devices ,Silicon cantilever ,Nanomechanical resonances ,Photonic crystals ,Optics ,Nanosensor ,Nanotechnology ,Resonance frequencies ,Photonic crystal ,Sensors ,business.industry ,Photonic crystal nanocavities ,Computer simulation ,Nanocantilevers ,chemistry ,Q factor ,Optoelectronics ,Photonics ,business ,Beam (structure) ,Photonic crystal nanocavity - Abstract
Optomechanical nanocavities allow nanomechanical resonances to be measured optically with high sensitivity. We have created a new type of photonic crystal nanocavity optomechanical sensor optimized for detecting sources of torque and other forces which can deflect nanoscale cantilevers. This nanocavity consists of two precisely engineered photonic Bragg mirrors patterned in silicon cantilevers and separated by a 50-100 nm wide gap. Simulations of the optical and mechanical modes predict that mechanical displacements of the sub-picogram cantilevers will shift the optical nanocavity resonance frequency at a rate exceeding 20 GHz / nm, and that the nanocavity optical mode may have a quality factor Qo > 10⁶in optimized devices., 13th International Conference on Numerical Simulation of Optoelectronic Devices, NUSOD 2013, August 19-22, 2013, Vancouver, BC, Canada, Series: Proceedings of the ... International Conference on Numerical Simulation of Optoelectronic Devices
- Published
- 2013
40. Photonic crystal split-beam nanocavities for torsional optomechanics
- Author
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Mark R. Freeman, Behzad Khanaliloo, Aaron C. Hryciw, Paul E. Barclay, John P. Davis, Chris Healey, and Marcelo Wu
- Subjects
Optical fiber ,Materials science ,Optical resonators ,Embedded systems ,Magnetometry ,Silicon photonics ,Nanophotonics ,Physics::Optics ,Opto-mechanics ,law.invention ,Photonic crystals ,Resonator ,Optics ,Mechanical resonators ,law ,Nanotechnology ,Integrated device ,Optical fibers ,Resonators ,Nanomagnetics ,Optomechanics ,Environmental stimuli ,Photonic crystal ,Laser resonators ,business.industry ,Magnetometers ,Photonics ,Nanolithography ,Optoelectronics ,Nanomechanical resonators ,business ,Beam (structure) ,Photonic crystal nanocavity - Abstract
Laser Resonators, Microresonators, and Beam Control XV, February 3-7, 2013, San Francisco, CA, USA, Series: Proceedings of SPIE
- Published
- 2013
41. Near-field cavity optomechanical probing of nanomechanics
- Author
-
Behzad Khanaliloo, Chris Healey, Paul E. Barclay, Aaron C. Hryciw, and Marcelo Wu
- Subjects
Optical amplifier ,Materials science ,Optical fiber ,business.industry ,Physics::Optics ,Near and far field ,Microstructured optical fiber ,Waveguide (optics) ,law.invention ,Optics ,law ,Optical cavity ,Optoelectronics ,Physics::Accelerator Physics ,business ,Nanomechanics ,Photonic crystal - Abstract
An optical fiber taper placed in the near field of a "split-beam" photonic crystal nanobeam cavity with a physical gap at the cavity center breaks the system's vertical dielectric symmetry, enabling selective optomechanical coupling to multiple cantilever resonances using a single optical nanocavity mode. © 2013 Optical Society of America., CLEO: QELS_Fundamental Science, CLEO:QELS FS 2013, June 9-14, 2013, San Jose, CA, USA
- Published
- 2013
42. Early morning birdwalk
- Author
-
Dr. Chris Healey, Dr. Julia Colleen Miller, Jimmy Nébni, Professor Nicholas Evans, Dr. Chris Healey, Dr. Julia Colleen Miller, Jimmy Nébni, and Professor Nicholas Evans
- Abstract
These recordings were collected during an early morning birdwalk in Zeri. The recordings were made with a Zoom H4N and two external microphones: a head-mounted mic recording our main consultant Jimmy Nebni. The second external microphone was a shotgun (hyper-directional) to collect bird songs. The on-board Zoom mics recorded the ambient noise and conversations between the rest of the participants, including the researchers. Key to file names:
.wav = on-board zoom track hm.wav = the isolated head-mounted track (main speaker) sg.wav = the isolated shotgun track (bird song) hmsg.wav = the combined main speaker and bird song tracks Keywords: Birds, This project focuses on collecting multimedia documentation of multiple undescribed Papuan languages – Nen and Nambu (Morehead-Maro) and Kmntso (Tonda). Other nearby languages will have varrying degrees of description, including Idi, Nama, and Neme. All of these languages belong to an almost completely unknown family in Southern New Guinea. Based at the Australian National University in Canberra, plus collaborations with the Max Planck Institute for Evolutionary Anthropology in Leipzig, the Friedrich-Schiller-Universität Jena, and the PNG National Herbarium, the project will embed a German PhD student (Christian Döhler) in a team including a seasoned field linguist (Nick Evans) and a post-doc (Julia Colleen Miller), two Germany-based typologists (Bernard Comrie and Volker Gast) from the FAUST (Future Archive User Simulation Team), plus participation on targeted fieldtrips by ethnobiologist Chris Healey (ANU) and botanist Kipiro Damas (PNG National Herbarium, Madang). Particular foci of the documentation will be the natural world (especially ethnobotany and ethnoornithology), swidden cultivation, fire management and ethnoecology, mythology, auto-ethnography, ethnomathematics, and microvariation in language use in a situation of daily multilingualism.nichola - Published
- 2012
43. nqn20120803-03
- Author
-
Dr. Julia Colleen Miller, Dr. Penelope Johnson, Jimmy Nébni, Professor Nicholas Evans, Rusian Nébni, Doreen Wenembu, Dr. Chris Healey, Dr. Julia Colleen Miller, Dr. Penelope Johnson, Jimmy Nébni, Professor Nicholas Evans, Rusian Nébni, Doreen Wenembu, and Dr. Chris Healey
- Abstract
Trip to Jimmy's yam garden in Zeri. Multiple recording devices used. Audio files (JMa) recorded with Zoom H4N; video recorded using Canon G-12 digital camera (JMc) and Canon video camera (PJv). nqn20120830JMa-03-01.wav: discussion of rotten yams, taro types and small yams. nqn20120830JMa-03-02.wav: yam planting magic, first told in English, then in Nen. nqn20120830JMa-03-03.wav: the importance of fertilizing yam gardens; black taro (kabian); planting stake (petin); yam type (kndsnd). nqn20120830JMa-03-04.wav: diggin yams in a second location in the garden (matching video: nqn20120830JMc-03-04.mpg); more on the purpose of small yams vs. large yams. nqn20120830JMa-03-05.wav: discussion of juggling game (adadu wir mäŋgus izärus). Associated photos are included in this session. Keywordsː gardening; plants; procedural, This project focuses on collecting multimedia documentation of multiple undescribed Papuan languages – Nen and Nambu (Morehead-Maro) and Kmntso (Tonda). Other nearby languages will have varrying degrees of description, including Idi, Nama, and Neme. All of these languages belong to an almost completely unknown family in Southern New Guinea. Based at the Australian National University in Canberra, plus collaborations with the Max Planck Institute for Evolutionary Anthropology in Leipzig, the Friedrich-Schiller-Universität Jena, and the PNG National Herbarium, the project will embed a German PhD student (Christian Döhler) in a team including a seasoned field linguist (Nick Evans) and a post-doc (Julia Colleen Miller), two Germany-based typologists (Bernard Comrie and Volker Gast) from the FAUST (Future Archive User Simulation Team), plus participation on targeted fieldtrips by ethnobiologist Chris Healey (ANU) and botanist Kipiro Damas (PNG National Herbarium, Madang). Particular foci of the documentation will be the natural world (especially ethnobotany and ethnoornithology), swidden cultivation, fire management and ethnoecology, mythology, auto-ethnography, ethnomathematics, and microvariation in language use in a situation of daily multilingualism.nichola, Rusian is originally from Arufi Village, a Nambo speaking site. Her clan is Bangu. She is married to Jimmy Nébni.
- Published
- 2012
44. How Many Highlands?D. K. Feil, The Evolution of Highland New Guinea Societies, Cambridge University Press, Cambridge, 1987, xii,313 pp. A$59.50
- Author
-
Chris Healey
- Subjects
media_common.quotation_subject ,General Earth and Planetary Sciences ,New guinea ,Art ,Ancient history ,General Environmental Science ,media_common - Published
- 1990
45. The National Museum of Australia as Danse Macabre: Baroque Allegories of the popular
- Author
-
Chris Healey and Andrea Witcomb, Macarthur, J, Stead, N, Chris Healey and Andrea Witcomb, Macarthur, J, and Stead, N
- Published
- 2006
46. Review
- Author
-
Chris Healey
- Subjects
History and Philosophy of Science ,Anthropology - Published
- 1997
47. Review
- Author
-
Chris Healey
- Subjects
History and Philosophy of Science ,Anthropology - Published
- 2005
48. Asian Women in PerspectiveGlenChandler NormaSullivan and JanBranson (eds.), Development and Displacement: Women in Southeast Asia, Centre of Southeast Asian Studies, Monash University, Clayton, Victoria, 1988, v, 136pp., A$14. Monash Papers on Southeast A
- Author
-
Chris Healey
- Subjects
Geography ,General Earth and Planetary Sciences ,Displacement (orthopedic surgery) ,Archaeology ,Southeast Asian studies ,General Environmental Science ,Southeast asia - Published
- 1990
49. REVIEW
- Author
-
Chris Healey
- Subjects
History and Philosophy of Science ,Anthropology - Published
- 1988
50. Reviews
- Author
-
Chris Healey
- Subjects
History and Philosophy of Science ,Anthropology - Published
- 1980
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