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22 results on '"Chou, Sophia"'

4. Unit Utilization of Internationally Educated Nurses and Collaboration in U.S. Hospitals

Author

Ma, Chenjuan, Ghazal, Lauren, Chou, Sophia, Ea, Emerson, and Squires, Allison

Subjects
Nursing education, Hospitals, Nursing, Nurses, Physicians, Globalization, Nursing research, Health
Abstract

Employing internationally educated nurses (IENs) to address the nursing workforce shortage is common in many countries, including the United States. This study examined the relationship between unit utilization of IENs and collaboration in U.S. hospitals. Results indicated more IENs on a unit did not significantly affect the collaboration among nurses and between nurses and physicians. The presence of IENs significantly influenced unit nursing characteristics, such as education attainment and unit tenure., With globalization increasing the mobility of nurses around the world, internationally educated nurses (IENs) are an important part of the nursing workforce in many countries. IENs are nurses who receive [...]

Published
2020

5. The Effect of Question Format and Task Difficulty on Reasoning Strategies and Diagnostic Performance in Internal Medicine Residents

Author

Heemskerk, Laura, Norman, Geoff, Chou, Sophia, Mintz, Marcy, Mandin, Henry, and McLaughlin, Kevin

Abstract

Background: Previous studies have suggested an association between reasoning strategies and diagnostic success, but the influence on this relationship of variables such as question format and task difficulty, has not been studied. Our objective was to study the association between question format, task difficulty, reasoning strategies and diagnostic success. Methods: Study participants were 13 Internal Medicine residents at the University of Calgary. Each was given eight problem-solving questions in four clinical presentations and were randomized to groups that differed only in the question format, such that a question presented as short answer (SA) to the first group was presented as extended matching (EM) to the second group. There were equal numbers of SA/EM questions and straightforward/difficult tasks. Participants performed think-aloud during diagnostic reasoning. Data were analyzed using multiple logistic regression. Results: Question format was associated with reasoning strategies; hypothetico-deductive reasoning being used more frequently on EM questions and scheme-inductive reasoning on SA questions. For SA question, non-analytic reasoning alone was used more frequently to answer straightforward cases than difficult cases, whereas for EM questions no such association was observed. EM format and straightforward task increased the odds of diagnostic success, whereas hypothetico-deductive reasoning was associated with reduced odds of success. Conclusions: Question format and task difficulty both influence diagnostic reasoning strategies and studies that examine the effect of reasoning strategies on diagnostic success should control for these effects. Further studies are needed to investigate the effect of reasoning strategies on performance of different groups of learners.

Published
2008
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7. Impact of quality improvement initiatives to improve CKD referral patterns: a systematic review protocol

Author

Ghimire, Anukul, primary, Sultana, Naima, additional, Ye, Feng, additional, Hamonic, Laura N, additional, Grill, Allan K, additional, Singer, Alexander, additional, Akbari, Ayub, additional, Braam, Branko, additional, Collister, David, additional, Jindal, Kailash, additional, Courtney, Mark, additional, Shah, Nikhil, additional, Ronksley, Paul E, additional, Shurraw, Sabin, additional, Brimble, Kenneth Scott, additional, Klarenbach, Scott, additional, Chou, Sophia, additional, Shojai, Soroush, additional, Deved, Vinay, additional, Wong, Andrew, additional, Okpechi, Ikechi, additional, and Bello, A K, additional

Published
2022
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11. Electronic Advice Request System for Nephrology in Alberta: Pilot Results and Implementation

Author

Bello, Aminu K, primary, Zaidi, Deenaz, additional, Braam, Branko, additional, Chou, Sophia, additional, Courtney, Mark, additional, Deved, Vinay, additional, Glassford, Jodi, additional, Jindal, Kailash, additional, Klarenbach, Scott, additional, Osman, Mohammed, additional, Scott-Douglas, Nairne, additional, Shurraw, Sabin, additional, Thompson, Stephanie, additional, Manns, Braden, additional, Hemmelgarn, Brenda, additional, and Tonelli, Marcello, additional

Published
2019
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12. Benevolence Repaid with Malevolence: How can Ethical Leaders Sustain Moral Motivation?

Author

Chou, Sophia

Abstract

In the realm of ethical leadership, good deeds can paradoxically lead to adverse outcomes, presenting psychological challenges that may erode moral motivation, a phenomenon underpinned by cognitive dissonance theory and schema theory. This dilemma has been noted in various philosophical traditions but remains insufficiently explored in social science. Addressing this gap, this research employed an inductive multiple-case approach, interviewing 23 ethical leaders to explore psychological strategies for sustaining moral motivation amidst such challenges. It identified three primary methods for upholding ethical volition under such circumstances: (1) schema assimilation: reinterpreting negative experiences; (2) schema shift: refocusing on core values; (3) schema transcendence: going beyond schema-reality conflicts. These findings not only enrich the ethical leadership literature but also offer practical strategies for ethical leadership development. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Splice site and de novo mutations can cause mixed dominant negative/gain of function PLCG2 -associated immune dysregulation with cold urticaria (CU-PLAID).

Author

Chou SR, Bailey AC, Baysac K, Oler AJ, Milner JD, and Ombrello MJ

Abstract

Background: Phospholipase Cγ2 (PLCγ2) is an important signaling molecule that receives and transmits signals from various cell surface receptors in most hematopoietic lineages. Variants of PLCG2 cause PLCγ2-associated immune dysregulation (PLAID), a family of conditions that are classified by mutational effect. PLAID with cold urticaria (CU-PLAID) is caused by in-frame deletions of PLCG2 that are dominant negative at physiologic temperatures but become spontaneously active at sub-physiologic temperatures., Objective: To identify genetic lesions that cause PLAID by combining RNA sequencing of full-length PLCG2 with whole genome sequencing., Methods: We studied nine probands with antibody deficiency and a positive evaporative cooling test, together with two known CU-PLAID patients and three healthy subjects. Illumina sequencing was performed on full-length PLCG2 cDNA synthesized from peripheral blood mononuclear cell RNA and whole genome sequencing was used to identify genetic lesions. Novel alternate transcripts were overexpressed in the Plcg2 -deficient DT40 cell overexpression system. ERK phosphorylation was quantified by flow cytometry with and without BCR crosslinking., Results: Two probands expressed novel alternative transcripts of PLCG2 with in-frame deletions. The first, expressing PLCG2 without exons 18-19, carried a splice site mutation in intron 19. The second, expressing PLCG2 without exons 19-22, carried a 14kb de novo deletion of PLCG2 . DT40 cells overexpressing the exon 18-19 or exon 19-22 deletions failed to phosphorylate ERK in response to BCR crosslinking., Conclusion: In addition to autosomal dominant genomic deletions, de novo deletions and splice site mutations of PLCG2 can also cause CU-PLAID. All of these can be identified by cDNA-based sequencing., Competing Interests: Conflict of Interest Disclosure: SRC, none; ACB, none; KB, none, AJO, none, JDM, none; MJO, none

Published
2024
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