1. An Unusual Case of Clear Cell Chondrosarcoma With Early Metastatic Recurrence.
- Author
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Kasson L, Vijayakumar G, Lee L, Gusho C, Braun A, Miller I, Colman MW, and Blank AT
- Subjects
- Humans, Male, Middle Aged, Fatal Outcome, Spinal Neoplasms secondary, Spinal Neoplasms diagnosis, Spinal Neoplasms surgery, Spinal Neoplasms pathology, Neoplasm Recurrence, Local pathology, Neoplasm Recurrence, Local diagnosis, Thoracic Vertebrae pathology, Thoracic Vertebrae surgery, Chondrosarcoma secondary, Chondrosarcoma diagnosis, Chondrosarcoma pathology, Chondrosarcoma surgery, Bone Neoplasms diagnosis, Bone Neoplasms secondary, Bone Neoplasms pathology, Bone Neoplasms surgery, Humerus pathology, Humerus surgery
- Abstract
We present a case of a 58-year-old male who presented following 4 months of progressively worsening right upper extremity pain. Initial pathology demonstrated pleomorphic chondroblasts with increased mitotic activity indicating an intermediate grade (Grade 2) clear cell chondrosarcoma of the proximal humerus. Following surgical resection, the primary lesion demonstrated aggressive behavior and early metastasis to the cervical and thoracic spine. The patient unfortunately expired 30 months after initial presentation. Although clear cell chondrosarcoma has been historically regarded as low grade, we present a unique example of an aggressive clinical course of clear cell chondrosarcoma., Competing Interests: Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
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