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3. Exercise capacity-hemodynamics mismatch in elderly patients with pulmonary hypertension: A nationwide multicenter study from Taiwan Society of Cardiology Pulmonary Hypertension Registry (TAIPANS)

Author

Chen, Chang-Ying, Mei-Tzu, Wang, Sung, Shih-Hsien, Wu, Yih-Jer, Hsu, Chih-Hsin, Ho, Wan-Jing, Lin, Yen-Hung, Liu, Wei-Shin, Liu, Ju-Chi, Kao, Yung-Ta, Wu, Wen-Shiann, Wu, Chun-Hsien, Lei, Meng-Huan, Chen, Yu-Wei, Chen-Yu, Chien, Chiu, Yu-Wei, Dai, Zen-Kong, Lin, Tsung-Hsien, Lin, Lin, Chung, Cheng-Chih, Chung, Chang-Min, Huang, Sung-Hao, Cheng, Chin-Chang, Wu, Yen-Wen, Chao, Ting-Hsing, Hwang, Juey-Jen, Jia-Yin Hou, Charles, and Huang, Wei-Chun

Published
2024
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5. 2022 Taiwanese Dermatological Association (TDA), Taiwanese Association for Psoriasis and Skin Immunology (TAPSI), and Taiwan Society of cardiology (TSOC) joint consensus recommendations for the management of psoriatic disease with attention to cardiovascular comorbidities

Author

Chi, Ching-Chi, Wu, Yen-Wen, Chao, Ting-Hsing, Chen, Chih-Chiang, Chen, Yi-Ju, Cheng, Hao-Min, Chiu, Hsien-Yi, Chiu, Yu-Wei, Chung, Wen-Hung, Hsieh, Tsu-Yi, Huang, Po-Hsun, Huang, Yu-Huei, Lin, Shang-Hung, Lin, Tsung-Hsien, Ueng, Kwo-Chang, Wang, Chun-Chieh, Wang, Yu-Chen, Wu, Nan-Lin, Jia-Yin Hou, Charles, and Tsai, Tsen-Fang

Published
2023
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8. Radiomic biomarkers for platinum‐refractory head and neck cancer in the era of immunotherapy.

Author

Lu, Hsueh‐Ju, Shen, Chao‐Yu, Chiu, Yu‐Wei, Lin, Wea‐Lung, Peng, Chih‐Yu, Tseng, Hsien‐Chun, Hsin, Chung‐Han, Chuang, Chun‐Yi, Chen, Chun‐Chia, Wu, Ming‐Fang, Huang, Wei‐Shiou, and Shen, Wei‐Chih

Subjects
MORTALITY risk factors, SQUAMOUS cell carcinoma, RISK assessment, CISPLATIN, RESEARCH funding, CANCER relapse, PREDICTION models, RADIOMICS, HEAD & neck cancer, IMMUNOTHERAPY, PROGRAMMED death-ligand 1, TUMOR markers, CARBOPLATIN, DECISION making in clinical medicine, RETROSPECTIVE studies, DESCRIPTIVE statistics, IMMUNE checkpoint inhibitors, METASTASIS, GENE expression, DRUG efficacy, OVERALL survival, EVALUATION
Abstract

Objective: Immune checkpoint inhibitors (ICI) are recommended as the first‐line therapy for platinum‐refractory head and neck squamous cell carcinoma (HNSCC), a disease with a poor prognosis. However, biomarkers in this situation are rare. The objective was to identify radiomic features‐associated biomarkers to guide the prognosis and treatment opinions in the era of ICI. Methods: A total of 31 platinum‐refractory HNSCC patients were retrospectively enrolled. Of these, 65.5% (20/31) received ICI‐based therapy and 35.5% (11/31) did not. Radiomic features of the primary site at the onset of recurrent metastatic (R/M) status were extracted. Prognostic and predictive radiomic biomarkers were analysed. Results: The median overall survival from R/M status (R/M OS) was 9.6 months. Grey‐level co‐occurrence matrix‐associated texture features were the most important in identifying the patients with or without 9‐month R/M death. A radiomic risk‐stratification model was established and equally separated the patients into high‐, intermittent‐ and lower‐risk groups (1‐year R/M death rate, 100.0% vs. 70.8% vs. 27.1%, p = 0.001). Short‐run high grey‐level emphasis (SRHGE) was more suitable than programmed death ligand 1 (PD‐L1) expression in selecting whether patients received ICI‐based therapy. Conclusions: Radiomic features were effective prognostic and predictive biomarkers. Future studies are warranted. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Parameters to assess the necessity of adjuvant therapy for early‐stage oral squamous cell carcinoma.

Author

Lu, Hsueh‐Ju, Chiu, Yu‐Wei, Peng, Chih‐Yu, Tseng, Hsien‐Chun, Hsin, Chung‐Han, Chuang, Chun‐Yi, Fan, Sheng, Huang, Wei‐Shiou, and Yang, Shun‐Fa

Subjects
*CANCER invasiveness, *SQUAMOUS cell carcinoma, *OVERALL survival, *MOUTH tumors, *SURVIVAL rate
Abstract

Objective Methods Results Conclusions One‐third of head and neck squamous cell carcinomas are early‐stage oral cavity squamous cell carcinomas (OCSCC). Despite a high curative rate, 20% of early‐stage OCSCC patients do not achieve long‐term survival. This study evaluates the role of adjuvant therapy (ADJ) in delaying disease progression and prolonging survival.This single‐institute retrospective cohort study enrolled 481 early‐stage OCSCC patients, 16% (78/481) of whom received ADJ. It was reported according to the STROBE guidelines. Cox proportional hazards regression and Kaplan–Meier survival curves were employed to identify suitable candidates for ADJ.The 5‐year locoregional recurrence‐free survival (LR‐RFS) and overall survival rates were 73.2% and 84.9%, respectively. Positive margins and advanced depth of invasion (DOI) were independent predictors of LR‐RFS. For patients with positive margins, adjuvant chemoradiotherapy (CRT) was superior to adjuvant radiotherapy alone in improving LR‐RFS (hazard ratios for adjuvant CRT vs. none, 0.042; adjuvant radiotherapy alone vs. none, 0.702). Excluding positive margins, advanced DOI was the most critical factor in assessing the need for ADJ. Positive margins and advanced DOI were more appropriate criteria than EORTC 22931/RTOG 9501 for evaluating adjuvant CRT.Adjuvant CRT was indicated for patients with positive margins and advanced DOI to improve survival outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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10. De Novo Biopsy-Proven Glomerular Disease Following COVID-19 Vaccination.

Author

Chen, Cheng-Hsu, Chiu, Yu-Wei, Chen, Bo-Ding, Wu, Ming-Ju, and Tsai, Shang-Feng

Subjects
*COVID-19, *KIDNEY glomerulus diseases, *IGA glomerulonephritis, *ANTINEUTROPHIL cytoplasmic antibodies, *RENAL biopsy, *FOCAL segmental glomerulosclerosis
Abstract

Background: There is still no consensus about the coronavirus disease 2019 (COVID-19) vaccine-associated glomerular disease (CVAGD). Given the large number of vaccinations administered and the variations in glomerulopathy observed across different countries and regional environments, CVAGD remains an important area of concern. Aim of study: We aimed to elucidate the findings of CVAGD within a Taiwanese cohort using biopsy data. Additionally, we endeavored to clarify the presentation of CVAGD. Methods: We collected data from patients who underwent renal biopsy from June 2021 to October 2022 at Taichung Veterans General Hospital. Two independent nephrologists meticulously reviewed the charts to exclude cases unrelated to vaccination. Results: Initially, a total of 286 patients underwent renal biopsy at our institute. Ultimately, we identified 14 patients with highly suspected CVAGD. All 14 patients exhibited proteinuria and hematuria. The urinary protein-to-creatinine ratio was elevated (median of 2012.1 mg/g; interquartile range (IQR) 25%–IQR 75%: 941.85–3884.1 mg/g) with a median serum creatinine level of 1.71 mg/dL (0.79–5.35). The majority of CVAGD cases were diagnosed as immunoglobulin A (IgA) nephropathy (n = 5, 35.7%), followed by antineutrophil cytoplasmic antibody (ANCA)-related rapidly progressive glomerulonephritis (RPGN) (n = 4, 28.6%). There were only three cases of minimal change disease each: one case of focal segmental glomerulosclerosis, one of membranous glomerulonephritis, and one of lupus nephritis. The culprit of COVID-19 vaccinations was 35.7% (n = 5) of Oxford-AstraZeneca (ChAdOx1-S), 42.9% (n = 6) of Moderna, and 21.4% (n = 3) of BNT162b2. Most patients experienced improvements in renal function. Only two cases of P-ANCA RPGN and one case of IgA nephropathy did not recover. Eighty percent of IgA nephropathy cases had favorable outcomes, but none of the patients with P-ANCA RPGN achieved full recovery. Conclusions: IgA nephropathy and ANCA-related RPGN were the most common CVAGD, and all types of COVID-19 vaccines posed a risk for CVAGD. However, further studies are required to confirm causality. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Reversal of arterial stiffness in medically and surgically treated unilateral primary aldosteronism

Author

Chen, Zheng-Wei, primary, Liao, Che-Wei, additional, Pan, Chien-Ting, additional, Tsai, Cheng-Hsuan, additional, Chang, Yi-Yao, additional, Chang, Chin-Chen, additional, Lee, Bo-Ching, additional, Chiu, Yu-Wei, additional, Huang, Wei-Chieh, additional, Lai, Tai-Shuan, additional, Lu, Ching-Chu, additional, Chueh, Jeff S., additional, Wu, Vin-Cent, additional, Hung, Chi-Sheng, additional, and Lin, Yen-Hung, additional

Published
2023
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19. 2023 Taiwan Society of Cardiology (TSOC) and Taiwan College of Rheumatology (TCR) Joint Consensus on Connective Tissue Disease-Associated Pulmonary Arterial Hypertension

Author

Huang, Wei-Chun, Hsieh, Song-Chou, Wu, Yen-Wen, Hsieh, Tsu-Yi, Wu, Yih-Jer, Li, Ko-Jen, Charng, Min-Ji, Chen, Wei-Sheng, Sung, Shih-Hsien, Tsao, Yen-Po, Ho, Wan-Jing, Lai, Chien-Chih, Cheng, Chin-Chang, Tsai, Hung-Cheng, Hsu, Chih-Hsin, Lu, Cheng-Hsun, Chiu, Yu-Wei, Shen, Chieh-Yu, Wu, Chun-Hsien, Liu, Feng-Cheng, Lin, Yen-Hung, Yeh, Fu-Chiang, Liu, Wei-Shin, Lee, Hui-Ting, Wu, Shu-Hao, Chang, Chi-Ching, Chu, Chun-Yuan, Hou, Charles Jia-Yin, and Tsai, Chang-Youh

Subjects
Consensus
Abstract

BACKGROUND: Pulmonary arterial hypertension (PAH), defined as the presence of a mean pulmonary artery pressure > 20 mmHg, pulmonary artery wedge pressure ≤ 15 mmHg, and pulmonary vascular resistance (PVR) > 2 Wood units based on expert consensus, is characterized by a progressive and sustained increase in PVR, which may lead to right heart failure and death. PAH is a well-known complication of connective tissue diseases (CTDs), such as systemic sclerosis, systemic lupus erythematosus, Sjogren’s syndrome, and other autoimmune conditions. In the past few years, tremendous progress in the understanding of PAH pathogenesis has been made, with various novel diagnostic and screening methods for the early detection of PAH proposed worldwide. OBJECTIVES: This study aimed to obtain a comprehensive understanding and provide recommendations for the management of CTD-PAH in Taiwan, focusing on its clinical importance, prognosis, risk stratification, diagnostic and screening algorithm, and pharmacological treatment. METHODS: The members of the Taiwan Society of Cardiology (TSOC) and Taiwan College of Rheumatology (TCR) reviewed the related literature thoroughly and integrated clinical trial evidence and real-world clinical experience for the development of this consensus. CONCLUSIONS: Early detection by regularly screening at-risk patients with incorporations of relevant autoantibodies and biomarkers may lead to better outcomes of CTD-PAH. This consensus proposed specific screening flowcharts for different types of CTDs, the risk assessment tools applicable to the clinical scenario in Taiwan, and a recommendation of medications in the management of CTD-PAH.

Published
2023

21. Comparative Analysis of 3D-Culture System for Murine Neonatal Heart Regeneration: A Systematic Approach for Big Gene Expression Data

Author

Weng, Julia Tzu-Ya, Chen, Yi-Cheng, Chang, Pei-Chann, Huang, Shin-Ping, Chiu, Yu-Wei, Goebel, Randy, Series editor, Tanaka, Yuzuru, Series editor, Wahlster, Wolfgang, Series editor, Peng, Wen-Chih, editor, Wang, Haixun, editor, Bailey, James, editor, Tseng, Vincent S., editor, Ho, Tu Bao, editor, Zhou, Zhi-Hua, editor, and Chen, Arbee L.P., editor

Published
2014
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22. Comparison of Home and Ambulatory Blood Pressure Measurements in Association With Preclinical Hypertensive Cardiovascular Damage

Author

Lin, Ting-Tse, Juang, Jimmy Jyh-Ming, Lee, Jen-Kuang, Tsai, Chia-Ti, Chen, Chen-Huan, Yu, Wen-Chung, Cheng, Hao-min, Wu, Yen-Wen, Chiu, Yu-Wei, Kuo, Chi-Tai, Chen, Jin-Jer, Chen, Zhih-Cherng, Chang, Wei-Ting, Liu, Ping-Yen, Chen, Po-wei, Yen, Hsueh-Wei, Chen, Ying-Chih, Tseng, Wei-Kung, Chiang, Fu-Tien, and Wu, Cho-Kai

Published
2019
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23. Implication of MR Activity in Posttreatment Arterial Stiffness Reversal in Patients With Primary Aldosteronism

Author

Chen, Zheng-Wei, primary, Pan, Chien-Ting, additional, Liao, Che-Wei, additional, Tsai, Cheng-Hsuan, additional, Chang, Yi-Yao, additional, Chang, Chin-Chen, additional, Lee, Bo-Ching, additional, Chiu, Yu-Wei, additional, Huang, Wei-Chieh, additional, Wang, Shuo-Meng, additional, Lu, Ching-Chu, additional, Chueh, Jeff S, additional, Wu, Vin-Cent, additional, Hung, Chi-Sheng, additional, and Lin, Yen-Hung, additional

Published
2022
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24. 2022 Taiwanese Dermatological Association (TDA), Taiwanese Association for Psoriasis and Skin Immunology (TAPSI), and Taiwan Society of cardiology (TSOC) joint consensus recommendations for the management of psoriatic disease with attention to cardiovascular comorbidities

Author

Chi, Ching-Chi, primary, Wu, Yen-Wen, additional, Chao, Ting-Hsing, additional, Chen, Chih-Chiang, additional, Chen, Yi-Ju, additional, Cheng, Hao-Min, additional, Chiu, Hsien-Yi, additional, Chiu, Yu-Wei, additional, Chung, Wen-Hung, additional, Hsieh, Tsu-Yi, additional, Huang, Po-Hsun, additional, Huang, Yu-Huei, additional, Lin, Shang-Hung, additional, Lin, Tsung-Hsien, additional, Ueng, Kwo-Chang, additional, Wang, Chun-Chieh, additional, Wang, Yu-Chen, additional, Wu, Nan-Lin, additional, Jia-Yin Hou, Charles, additional, and Tsai, Tsen-Fang, additional

Published
2022
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25. sj-docx-1-taj-10.1177_20406223221143253 – Supplemental material for Anatomical and functional remodeling of left ventricle in patients with primary aldosteronism and concomitant albuminuria

Author

Kao, Ting-Wei, Wu, Xue-Ming, Liao, Che-Wei, Tsai, Cheng-Hsuan, Chen, Zheng-Wei, Chang, Yi-Yao, Lee, Bo-Ching, Chiu, Yu-Wei, Lai, Tai-Shuan, Wu, Vin-Cent, Lin, Yen-Hung, and Hung, Chi-Sheng

Subjects
FOS: Psychology, 110203 Respiratory Diseases, FOS: Clinical medicine, Cardiology, 170199 Psychology not elsewhere classified, 111702 Aged Health Care, FOS: Health sciences, 110319 Psychiatry (incl. Psychotherapy), 110306 Endocrinology, 110308 Geriatrics and Gerontology, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-docx-1-taj-10.1177_20406223221143253 for Anatomical and functional remodeling of left ventricle in patients with primary aldosteronism and concomitant albuminuria by Ting-Wei Kao, Xue-Ming Wu, Che-Wei Liao, Cheng-Hsuan Tsai, Zheng-Wei Chen, Yi-Yao Chang, Bo-Ching Lee, Yu-Wei Chiu, Tai-Shuan Lai, Vin-Cent Wu, Yen-Hung Lin and Chi-Sheng Hung in Therapeutic Advances in Chronic Disease

Published
2023
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28. Improving the Diagnostic Performance by Adding Methylation Marker to Conventional Visual Examination in Identifying Oral Cancer

Author

Yang, Cheng-Chieh, primary, Su, Yee-Fun, additional, Cheng, Han-Chieh, additional, Juan, Yi-Chen, additional, Chiu, Yu-Wei, additional, Wu, Cheng-Hsien, additional, Chen, Pei-Yin, additional, Lee, Yu-Hsien, additional, Chen, Yen-Lin, additional, Chen, Yi-Tzu, additional, Peng, Chih-Yu, additional, Lu, Ming-Yi, additional, Yu, Chuan-Hang, additional, Huang, Yu-Feng, additional, Kao, Shou-Yen, additional, Fwu, Chyng-Wen, additional, and Liu, Chung-Ji, additional

Published
2022
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29. Is OLP potentially malignant? A clue from ZNF582 methylation.

Author

Chiu, Yu‐Wei, Su, Yee‐Fun, Yang, Cheng‐Chieh, Liu, Chung‐Ji, Chen, Yi‐Ju, Cheng, Han‐Chieh, Wu, Cheng‐Hsien, Chen, Pei‐Yin, Lee, Yu‐Hsien, Chen, Yen‐Lin, Chen, Yi‐Tzu, Peng, Chih‐Yu, Lu, Ming‐Yi, Yu, Chuan‐Hang, Kao, Shou‐Yen, Fwu, Chyng‐Wen, and Huang, Yu‐Feng

Subjects
*RISK-taking behavior, *ORAL lichen planus, *CASE-control method, *COMPARATIVE studies, *GENES, *METHYLATION, *DESCRIPTIVE statistics, *TUMOR markers, *PRECANCEROUS conditions, *SQUAMOUS cell carcinoma
Abstract

Objective: Whether oral lichen planus (OLP) was potentially malignant remains controversial. Here, we examined associations of ZNF582 methylation (ZNF582m) with OLP lesions, dysplastic features and squamous cell carcinoma (OSCC). Materials and Methods: This is a case–control study. ZNF582m was evaluated in both lesion and adjacent normal sites of 42 dysplasia, 90 OSCC and 43 OLP patients, whereas ZNF582m was evaluated only in one mucosal site of 45 normal controls. High‐risk habits affecting ZNF582m such as betel nut chewing and cigarette smoking were also compared in those groups. Results: OLP lesions showed significantly lower ZNF582m than those of dysplasia and OSCC. At adjacent normal mucosa, ZNF582m increased from patients of OLP, dysplasia, to OSCC. In addition, ZNF582m at adjacent normal sites in OLP patients was comparable to normal mucosa in control group. Dysplasia/OSCC patients with high‐risk habits exhibited significantly higher ZNF582m than those without high‐risk habits. However, ZNF582m in OLP patients was not affected by those high‐risk habits. Conclusions: OLP is unlikely to be potentially malignant based on ZNF582m levels. ZNF582m may also be a potential biomarker for distinguishing OLP from true dysplastic features and OSCC, and for monitoring the malignant transformation of OLP, potentially malignant disorders with dysplastic features and OSCC. [ABSTRACT FROM AUTHOR]

Published
2023
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30. In reply of the comment ‘Is oral lichen planus potentially malignant: a reply to Yu‐Wei Chiu et al’

Author

Chiu, Yu‐Wei, primary, Su, Yee‐Fun, additional, Yang, Cheng‐Chieh, additional, Liu, Chung‐Ji, additional, Chen, Yi‐Ju, additional, Cheng, Han‐Chieh, additional, Wu, Cheng‐Hsien, additional, Chen, Pei‐Yin, additional, Lee, Yu‐Hsien, additional, Chen, Yen‐Lin, additional, Chen, Yi‐Tzu, additional, Peng, Chih‐Yu, additional, Lu, Ming‐Yi, additional, Yu, Chuan‐Hang, additional, Kao, Shou‐Yen, additional, Fwu, Chyng‐Wen, additional, and Huang, Yu‐Feng, additional

Published
2022
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31. KCNJ5 Somatic Mutation Is Associated With Higher Aortic Wall Thickness and Less Calcification in Patients With Aldosterone-Producing Adenoma

Author

Lee, Bo-Ching, primary, Kang, Victor Jing-Wei, additional, Pan, Chien-Ting, additional, Huang, Jia-Zheng, additional, Lin, Yu-Li, additional, Chang, Yi-Yao, additional, Tsai, Cheng-Hsuan, additional, Chou, Chia-Hung, additional, Chen, Zheng-Wei, additional, Liao, Che-Wei, additional, Chiu, Yu-Wei, additional, Wu, Vin-Cent, additional, Hung, Chi-Sheng, additional, Chang, Chin-Chen, additional, and Lin, Yen-Hung, additional

Published
2022
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32. Is OLP potentially malignant? A clue from ZNF582 methylation

Author

Chiu, Yu‐Wei, primary, Su, Yee‐Fun, additional, Yang, Cheng‐Chieh, additional, Liu, Chung‐Ji, additional, Chen, Yi‐Ju, additional, Cheng, Han‐Chieh, additional, Wu, Cheng‐Hsien, additional, Chen, Pei‐Yin, additional, Lee, Yu‐Hsien, additional, Chen, Yen‐Lin, additional, Chen, Yi‐Tzu, additional, Peng, Chih‐Yu, additional, Lu, Ming‐Yi, additional, Yu, Chuan‐Hang, additional, Kao, Shou‐Yen, additional, Fwu, Chyng‐Wen, additional, and Huang, Yu‐Feng, additional

Published
2022
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34. Diabetes mellitus is associated with worse baseline and less post-treatment recovery of arterial stiffness in patients with primary aldosteronism

Author

Tsai, Cheng-Hsuan, primary, Wu, Xue-Ming, additional, Liao, Che-Wei, additional, Chen, Zheng-Wei, additional, Pan, Chien-Ting, additional, Chang, Yi-Yao, additional, Lee, Bo-Ching, additional, Chiu, Yu-Wei, additional, Lai, Tai-Shuan, additional, Wu, Vin-Cent, additional, Hung, Chi-Sheng, additional, and Lin, Yen-Hung, additional

Published
2022
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35. Heart-Ankle Pulse Wave Velocity Is Superior to Brachial-Ankle Pulse Wave Velocity in Detecting Aldosterone-Induced Arterial Stiffness

Author

Chen, Zheng-Wei, Pan, Chien-Ting, Tsai, Cheng-Hsuan, Chang, Yi-Yao, Chang, Chin-Chen, Lee, Bo-Ching, Chiu, Yu-Wei, Huang, Wei-Chieh, Lin, Yu-Li, Wu, Vin-Cent, Hung, Chi-Sheng, Liao, Che-Wei, Lin, Yen-Hung, and Group, on behalf of TAIPAI Study Group on behalf of TAIPAI Study

Subjects
medicine.medical_specialty, QH301-705.5, Medicine (miscellaneous), brachial-ankle pulse wave velocity, heart-ankle pulse wave velocity, Essential hypertension, General Biochemistry, Genetics and Molecular Biology, Article, chemistry.chemical_compound, Primary aldosteronism, Internal medicine, medicine, cardiovascular diseases, Biology (General), Pulse wave velocity, Aldosterone, primary aldosteronism, Receiver operating characteristic, business.industry, Wave velocity, medicine.disease, Blood pressure, arterial stiffness, chemistry, Arterial stiffness, Cardiology, cardiovascular system, business, circulatory and respiratory physiology
Abstract

Primary aldosteronism (PA) is associated with higher arterial stiffness compared to essential hypertension (EH). However, few studies have compared different pulse wave velocity (PWV) parameters to detect aldosterone-induced arterial stiffness. In this study, we aimed to compare the sensitivity in detecting aldosterone-induced arterial stiffness between brachial-ankle PWV (baPWV) and heart-ankle PWV (haPWV). We prospectively enrolled 1006 PA patients and 983 EH patients. Detailed medical history, basic biochemistry data and two PWV measurements (baPWV and haPWV) were collected in both groups. We performed analysis on the original cohort and two propensity score matching (PSM) models (model 1 adjusted for age and sex, model 2 adjusted for age, sex, systolic and diastolic blood pressure). The DeLong test was used to compare areas under receiver operating characteristic curves (AUCs) between baPWV and haPWV to predict PA. In all models, the PA patients had significantly higher baPWV compared to the EH patients. The AUC of haPWV was greater than that of baPWV. In conclusion, haPWV seems to be a better PWV parameter than baPWV in detecting aldosterone-induced arterial stiffness.

Published
2021

39. KCNJ5 Somatic Mutations in Aldosterone-Producing Adenoma Are Associated with a Greater Recovery of Arterial Stiffness

Author

Chang, Yi-Yao, primary, Pan, Chien-Ting, additional, Chen, Zheng-Wei, additional, Tsai, Cheng-Hsuan, additional, Peng, Shih-Yuan, additional, Chang, Chin-Chen, additional, Lee, Bo-Ching, additional, Liao, Che-Wei, additional, Peng, Kang-Yung, additional, Chiu, Yu-Wei, additional, Chou, Chia-Hung, additional, Wu, Vin-Cent, additional, Liu, Li-Yu Daisy, additional, Hung, Chi-Sheng, additional, and Lin, Yen-Hung, additional

Published
2021
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43. New-Onset Atrial Fibrillation in Patients With Primary Aldosteronism Receiving Different Treatment Strategies: Systematic Review and Pooled Analysis of Three Studies

Author

Tsai, Cheng-Hsuan, primary, Chen, Ya-Li, additional, Pan, Chien-Ting, additional, Lin, Yen-Tin, additional, Lee, Po-Chin, additional, Chiu, Yu-Wei, additional, Liao, Che-Wei, additional, Chen, Zheng-Wei, additional, Chang, Chin-Chen, additional, Chang, Yi-Yao, additional, Hung, Chi-Sheng, additional, and Lin, Yen-Hung, additional

Published
2021
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46. Modulators of Mortality Benefit From Peri-Angioplasty Adjunctive Tirofiban in Patients With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Author

Yeh, Yen-Ting, primary, Hsu, Jung-Chung, additional, Liao, Pen-Chih, additional, Li, Ai-Hsien, additional, Liu, Yuan-Hung, additional, Chen, Kuo-Chin, additional, Chuang, Wenpo, additional, Ke, Shin-Rong, additional, Chiu, Yu-Wei, additional, and Wu, Yen-Wen, additional

Published
2021
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