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4. Four-year overall surgical mortality rate at Princess Marina Hospital, a tertiary hospital in Botswana

Author

Chinyepi, Nkhabe, primary, Motsumi, Mpapho Joseph, additional, Rackara, Samuel, additional, Lwango, Rashid, additional, Kapinga, Getrude, additional, Ngwako, Karabo, additional, Sentsho, Maranatha, additional, Leshomo, Tefo, additional, Chilisa, Unami, additional, Lekgowe, Elijah Kopo, additional, Binikwa, Mogomotsi, additional, and Motlaleselelo, Pako, additional

Published
2023
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7. Outcomes after thoracic endovascular aortic repair (TEVAR) in patients with traumatic thoracic aortic injuries (TTAI) - a single center retrospective review

Author

Chinyepi, Nkhabe and Naidoo, Nadraj G

Subjects
General Surgery
Abstract

Background: Blunt and penetrating traumatic thoracic aortic injuries constitute surgical emergencies that are attended with high mortality rates. Most patients do not survive long enough, post injury, to reach a hospital. On-site mortality rates may approach approximately 85%. Two main treatment options for blunt thoracic aortic injuries (BTAI) are open surgery and thoracic endovascular repair (TEVAR). Penetrating thoracic aortic injuries (PTAI) have a higher mortality than blunt trauma, with patients often only reaching the hospital in extremis. Most will require early intervention. Currently TEVAR is rapidly evolving as the standard of care for thoracic aortic injuries (TAI) at many centres, primarily due to the emerging evidence of lower mortality and morbidity trends in comparison to open surgery (1–4). Methods: From December 2006 to December 2016, 34 patients (30 blunt trauma, 4 penetrating trauma) with traumatic aortic injuries (grades I-IV) were treated with thoracic aortic stent-grafts in the Groote Schuur Hospital Vascular Unit, Cape Town. We assessed the technical and clinical outcomes following TEVAR in these patients. Results: The 30- day mortality rate was 5.8%, corresponding to 2 deaths both associated with the index trauma-related fatal strokes. The overall mortality rate was 11.8% (4/34): three deaths were due to major strokes and one death was related to pulmonary complications. Conclusion: TEVAR after TAI is associated with significantly lower procedural and postoperative mortality. The 30 day and overall mortality after TEVAR in our unit is comparable to international standards. Even though there is a paucity of literature on PTAI, TEVAR has low peri-procedural adverse events and is safe in selected patients.

Published
2018

10. Corrigendum

Author

Seemungal,Terence, Lun,Johanna Cho Fook, Davis,Gershwin, Neblett,Carlos, Chinyepi,Nkhabe, Dookhan,Christina, Drakes,Samantha, Mandeville,Elizabeth, Nana,Nana, Setlhake,Seatshogeng, King,Celia Poon, Pinto Pereira,Lexley, Delisle,Jerome, Wilkinson,Thomas MA, Wedzicha,Jagwiga A, Seemungal,Terence, Lun,Johanna Cho Fook, Davis,Gershwin, Neblett,Carlos, Chinyepi,Nkhabe, Dookhan,Christina, Drakes,Samantha, Mandeville,Elizabeth, Nana,Nana, Setlhake,Seatshogeng, King,Celia Poon, Pinto Pereira,Lexley, Delisle,Jerome, Wilkinson,Thomas MA, and Wedzicha,Jagwiga A

Abstract

Seemungal TA, Lun JC, Davis G, et al. Plasma homocysteine is elevated in COPD patients and is related to COPD severity.International Journal of COPD. 2007;2(3):313–321. Dr Lexley Pinto Pereira’s name was incorrectly listed as ‘PintoPereira L’, instead of ‘Pinto Pereira L’.Original Article

Published
2011

11. Plasma homocysteine is elevated in COPD patients and is related to COPD severity

Author

Seemungal,Terence, Lun,Johanna Cho Fook, Davis,Gershwin, Neblett,Carlos, Chinyepi,Nkhabe, Dookhan,Christina, Drakes,Samantha, Mandeville,Elizabeth, Nana,Fatima, Setlhake,Seatshogeng, King,Celia Poon, PintoPereira,Lexley, Delisle,Jerome, Wilkinson,Thomas MA, Wedzicha,Jagwiga A, Seemungal,Terence, Lun,Johanna Cho Fook, Davis,Gershwin, Neblett,Carlos, Chinyepi,Nkhabe, Dookhan,Christina, Drakes,Samantha, Mandeville,Elizabeth, Nana,Fatima, Setlhake,Seatshogeng, King,Celia Poon, PintoPereira,Lexley, Delisle,Jerome, Wilkinson,Thomas MA, and Wedzicha,Jagwiga A

Abstract

Terence AR Seemungal1, Johanna Cho Fook Lun1, Gershwin Davis2, Carlos Neblett1, Nkhabe Chinyepi1, Christina Dookhan1, Samantha Drakes1, Elizabeth Mandeville1, Fatima Nana1, Seatshogeng Setlhake1, Celia Poon King2, Lexley Pinto Pereira2, Jerome Delisle3, Thomas MA Wilkinson4, Jagwiga A Wedzicha41Departments of Clinical Medical Sciences; 2Paraclinical Sciences; 3Centre for Medical Sciences Education; 4Faculty of Medical Sciences University of the West Indies, St Augustine Campus, Trinidad and Tobago; Academic Unit of Respiratory Medicine, University College Medical School, University College London, EnglandBackground: Although recent studies have found that total plasma homocysteine (tHCY) and chronic obstructive pulmonary disease (COPD) are both risk factors for cardiac disease, there have been few studies of plasma homocysteine levels in COPD patients. We tested the hypothesis that total plasma homocysteine (tHCY) would be elevated in patients diagnosed with COPD compared with controls.Methods: We studied 29 COPD outpatients and 25 asymptomatic subjects (controls) over age 55 years with measurement of forced expiratory volume in one second (FEV1), forced vital capacity (FVC), St. Georges Respiratory Questionnaire (SGRQ) score, tHCY and serum C-reactive protein (sCRP).Results: There was no difference between controls vs. COPD patients in mean age or gender but mean (SD) FEV1 was 2.25 (0.77) vs 1.43 (0.60) L; FEV1% predicted 76.1 (17.2) vs 49.1 (16.3) p < 0.001 in both cases. Median (IQR) tHCY was 8.22 (6.63, 9.55) in controls vs 10.96 (7.56, 13.60) micromol/l for COPD, p = 0.006 and sCRP 0.89 (0.47, 2.55) vs 2.05 (0.86, 6.19) mg/l, p = 0.023. tHCY(log) was also higher in (r, p) smokers (0.448, 0.001), patients with low FEV1% (−0.397, 0.003), males (0.475, <0.001), but high SGRQ Total score (0.289, 0.034), and high sCRP (0.316, 0.038). tHCY(log) was independently related to (regression coefficient, p) sCRP(log) (0.087, 0.024), male gen

Published
2007

13. Decolonizing Global Surgery: Bethune Round Table, 2022 Conference on Global Surgery (virtual), June 16-18, 2022.

Author

Botelho F, Gripp K, Yanchar N, Naus A, Poenaru D, Baird R, Reis E, Farias L, Silva AG, Viana F, Neto JAP, Silva S, Ribeiro K, Gatto L, Faleiro MD, Fernandez MG, Salgado LS, Sampaio NZ, Faleiro MD, Mendes AL, Ferreira RV, Marcião L, Canto G, Borges J, Araújo V, Andrade G, Braga J, Bentes L, Pinto L, Ndasi HT, Amlani LM, Aminake G, Penda X, Tima S, Lechtig A, Agarwal-Harding KJ, Whyte M, Fowler-Woods M, Fowler-Woods A, Shingoose G, Hatala A, Daeninck F, Vergis A, Clouston K, Hardy K, Djadje L, Djoutsop OM, Djabo AT, Kanmounye US, Youmbi VN, Kakobo P, Djoutsop OM, Djabo AT, Kanmounye US, Tafesse S, Tamene B, Chimdesa Z, Alemayehu E, Abera B, Yifru D, Belachew FK, Tirsit A, Deyassa N, Moen BE, Sundstrøm T, Lund-Johansen M, Abebe M, Khan R, Mekasha A, Soklaridis S, Haji F, Asingei J, O'Flynn EP, O'Donovan DT, Masuka SC, Mashava D, Akello FV, Ulisubisya MM, Franco H, Njai A, Simister S, Joseph M, Woolley P, James D, Evans FM, Rai E, Roy N, Bansal V, Kamble J, Aroke A, David S, Veetil D, Soni KD, Wärnberg MG, Zadey S, Vissoci JRN, Iyer H, Zadey S, Shetty R, Zadey S, Jindal A, Iyer H, Ouma G, Shah SSNH, Hinchman C, Rayel IM, Dworkin M, Agarwal-Harding KJ, Mlinde E, Amlani LM, May CJ, Banza LN, Chokotho L, Agarwal-Harding KJ, Dworkin M, Mbomuwa F, Chidothi P, Martin C Jr, Harrison WJ, Agarwal-Harding KJ, Chokotho L, Paek S, Amlani L, Mbomuwa F, Chidothi P, Martin C Jr, Harrison WJ, Agarwal-Harding KJ, Chokotho L, Adégné T, Abdoulmouinou P, Amadou T, Youssouf T, Madiassa K, Younoussa DM, Moussa S, Amadou B, Hawa T, Laurent A, Jesuyajolu DA, Okeke CA, Obuh O, Jesuyajolu DA, Ehizibue PE, Ikemefula NE, Ekennia-Ebeh JO, Ibraham AA, Ikegwuonu OE, Diehl TM, Bunogerane GJ, Neal D, Ndibanje AJ, Petroze RT, Ntaganda E, Milligan L, Cairncross L, Malherbe F, Roodt L, Kyengera DK, O'Hara NN, Stockton D, Bedada A, Hsiao M, Chilisa U, Yarranton B, Chinyepi N, Azzie G, Moon J, Rehany Z, Bakhshi M, Bergeron A, Boulanger N, Watt L, Wong EG, Pawlak N, Bierema C, Ameh E, Bekele A, Jimenez MF, Lakhoo K, Roy N, Sacato H, Tefera G, Ozgediz D, Jayaraman S, Peric I, Youngson G, Ameh E, Borgstein E, O'Flynn E, Simoes J, Kingsley PA, Sasson L, Dekel H, Sternfeld AR, Assa S, Sarid RS, Mnong'one NJ, Sharau GG, Mongella SM, Caryl WG, Goldman B, Bola R, Ngonzi J, Ujoh F, Kihumuro RB, Lett R, Torquato A, Tavares C, Lech G, Džunic A, Ujoh F, Gusa V, Apeaii R, Noor R, Bola R, Guyan IO, Christilaw J, Hodgins S, Lett R, Binda C, Heo K, Cheng S, Foggin H, Hu G, Lam S, Feng L, Labinaz A, Adams J, Livergant R, Williams S, Vasanthakumaran T, Lounes Y, Mata J, Hache P, Schamberg-Bahadori C, Monytuil A, Mayom E, Joharifard S, Joos É, Paterson A, Maswime S, Hardy A, Pearse RM, Biccard BM, Salehi M, Zivkovic I, Jatana S, Joharifard S, Joos É, Flores MJ, Brown KE, Roberts HJ, Donnelley CA, von Kaeppler EP, Eliezer E, Haonga B, Morshed S, and Shearer DW

Published
2022
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