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1. A Proof of the Central Limit Theorem Using the $2$-Wasserstein Metric

Author

Chin, Calvin Wooyoung

Subjects
Mathematics - Probability, 60F05
Abstract

We prove the Lindeberg--Feller central limit theorem without using characteristic functions or Taylor expansions, but instead by measuring how far a distribution is from the standard normal distribution according to the $2$-Wasserstein metric. This falls under the category of renormalization group methods. The facts we need about the metric are explained and proved in detail. We illustrate the idea on a classical version of the central limit theorem before going into the main proof., Comment: 10 pages

Published
2024

2. A Catalogue of Structural Variation across Ancestrally Diverse Asian Genomes

Author

Tan, Joanna Hui Juan, Li, Zhihui, Porta, Mar Gonzalez, Rajaby, Ramesh, Lim, Weng Khong, Tan, Ye An, Jimenez, Rodrigo Toro, Teo, Renyi, Hebrard, Maxime, Ow, Jack Ling, Ang, Shimin, Jeyakani, Justin, Chong, Yap Seng, Lim, Tock Han, Goh, Liuh Ling, Tham, Yih Chung, Leong, Khai Pang, Chin, Calvin Woon Loong, Davila, Sonia, Karnani, Neerja, Cheng, Ching-Yu, Chambers, John, Tai, E. Shyong, Liu, Jianjun, Sim, Xueling, Sung, Wing Kin, Prabhakar, Shyam, Tan, Patrick, and Bertin, Nicolas

Published
2024
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4. A Mass Transport Proof of the Ergodic Theorem

Author

Chin, Calvin Wooyoung

Subjects
Mathematics - Probability, 37A30, 60F15, 28D05
Abstract

It is known that a gambler repeating a game with positive expected value has a positive probability to never go broke. We use the mass transport method to prove the generalization of this fact where the gains from the bets form a stationary, rather than an i.i.d., sequence. Birkhoff's ergodic theorem follows from this by a standard argument., Comment: 4 pages, 2 figures

Published
2022

6. Deriving the Central Limit Theorem from the De Moivre-Laplace Theorem

Author

Chin, Calvin Wooyoung

Subjects
Mathematics - Probability, 60F05
Abstract

The de Moivre-Laplace theorem is a special case of the central limit theorem for Bernoulli random variables, and can be proved by direct computation. We deduce the central limit theorem for any random variable with finite variance from the de Moivre-Laplace theorem. Our proof does not use advanced notions such as characteristic functions, the Brownian motion, or stopping times., Comment: 5 pages

Published
2021

7. Cardiovascular Magnetic Resonance Reference Ranges From the Healthy Hearts Consortium

Author

Raisi-Estabragh, Zahra, Szabo, Liliana, McCracken, Celeste, Bülow, Robin, Aquaro, Giovanni Donato, Andre, Florian, Le, Thu-Thao, Suchá, Dominika, Condurache, Dorina-Gabriela, Salih, Ahmed M., Chadalavada, Sucharitha, Aung, Nay, Lee, Aaron Mark, Harvey, Nicholas C., Leiner, Tim, Chin, Calvin W.L., Friedrich, Matthias G., Barison, Andrea, Dörr, Marcus, and Petersen, Steffen E.

Published
2024
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8. Joint Semi-supervised 3D Super-Resolution and Segmentation with Mixed Adversarial Gaussian Domain Adaptation

Author

Savioli, Nicolo, de Marvao, Antonio, Bai, Wenjia, Wang, Shuo, Cook, Stuart A., Chin, Calvin W. L., Rueckert, Daniel, and O'Regan, Declan P.

Subjects
Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition
Abstract

Optimising the analysis of cardiac structure and function requires accurate 3D representations of shape and motion. However, techniques such as cardiac magnetic resonance imaging are conventionally limited to acquiring contiguous cross-sectional slices with low through-plane resolution and potential inter-slice spatial misalignment. Super-resolution in medical imaging aims to increase the resolution of images but is conventionally trained on features from low resolution datasets and does not super-resolve corresponding segmentations. Here we propose a semi-supervised multi-task generative adversarial network (Gemini-GAN) that performs joint super-resolution of the images and their labels using a ground truth of high resolution 3D cines and segmentations, while an unsupervised variational adversarial mixture autoencoder (V-AMA) is used for continuous domain adaptation. Our proposed approach is extensively evaluated on two transnational multi-ethnic populations of 1,331 and 205 adults respectively, delivering an improvement on state of the art methods in terms of Dice index, peak signal to noise ratio, and structural similarity index measure. This framework also exceeds the performance of state of the art generative domain adaptation models on external validation (Dice index 0.81 vs 0.74 for the left ventricle). This demonstrates how joint super-resolution and segmentation, trained on 3D ground-truth data with cross-domain generalization, enables robust precision phenotyping in diverse populations.

Published
2021

9. A Short and Elementary Proof of the Central Limit Theorem by Individual Swapping

Author

Chin, Calvin Wooyoung

Subjects
Mathematics - Probability, 60F05
Abstract

We present a short proof of the central limit theorem which is elementary in the sense that no knowledge of characteristic functions, linear operators, or other advanced results are needed. Our proof is based on Lindeberg's trick of swapping a term for a normal random variable in turn. The modifications needed to prove the stronger Lindeberg-Feller central limit theorem are addressed at the end., Comment: 6 pages, to be published in the American Mathematical Monthly

Published
2021

10. Mandibular Advancement vs CPAP for Blood Pressure Reduction in Patients With Obstructive Sleep Apnea

Author

Ou, Yi-Hui, Colpani, Juliana Tereza, Cheong, Crystal S., Loke, Weiqiang, Thant, As tar, Shih, E’ Ching, Lee, Frank, Chan, Siew-Pang, Sia, Ching-Hui, Koo, Chieh-Yang, Wong, Serene, Chua, Aiping, Khoo, Chin-Meng, Kong, William, Chin, Calvin W., Kojodjojo, Pipin, Wong, Philip E., Chan, Mark Y., Richards, A. Mark, Cistulli, Peter A., and Lee, Chi-Hang

Published
2024
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12. Water Conservation Overrides Osmotic Diuresis During SGLT2 Inhibition in Patients With Heart Failure

Author

Marton, Adriana, Saffari, Seyed Ehsan, Rauh, Manfred, Sun, Ruo-Ning, Nagel, Armin M., Linz, Peter, Lim, Tzy Tiing, Takase-Minegishi, Kaoru, Pajarillaga, Anastacia, Saw, Sharon, Morisawa, Norihiko, Yam, Wan Keat, Minegishi, Shintaro, Totman, John J., Teo, Serena, Teo, Louis L.Y., Ng, Choon Ta, Kitada, Kento, Wild, Johannes, Kovalik, Jean-Paul, Luft, Friedrich C., Greasley, Peter J., Chin, Calvin W.L., Sim, David K.L., and Titze, Jens

Published
2024
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13. Necessary and Sufficient Conditions for Convergence to the Semicircle Distribution

Author

Chin, Calvin Wooyoung

Subjects
Mathematics - Probability, 60B20
Abstract

We consider random Hermitian matrices with independent upper triangular entries. Wigner's semicircle law says that under certain additional assumptions, the empirical spectral distribution converges to the semicircle distribution. We characterize convergence to semicircle in terms of the variances of the entries, under natural assumptions such as the Lindeberg condition. The result extends to certain matrices with entries having infinite second moments. As a corollary, another characterization of semicircle convergence is given in terms of convergence in distribution of the row sums to the standard normal distribution., Comment: 23 pages, to be published in Random Matrices: Theory and Applications

Published
2021

14. A Gambler that Bets Forever and the Strong Law of Large Numbers

Author

Chin, Calvin Wooyoung

Subjects
Mathematics - Probability, Mathematics - History and Overview, 60G50, 60F15
Abstract

In this expository note, we give a simple proof that a gambler repeating a game with positive expected value never goes broke with a positive probability. This does not immediately follow from the strong law of large numbers or other basic facts on random walks. Using this result, we provide an elementary proof of the strong law of large numbers. The ideas of the proofs come from the maximal ergodic theorem and Birkhoff's ergodic theorem., Comment: 3 pages, 1 figure, to be published in the American Mathematical Monthly

Published
2021

15. The Singapore National Precision Medicine Strategy

Author

Wong, Eleanor, Bertin, Nicolas, Hebrard, Maxime, Tirado-Magallanes, Roberto, Bellis, Claire, Lim, Weng Khong, Chua, Chee Yong, Tong, Philomena Mei Lin, Chua, Raymond, Mak, Kenneth, Lim, Tit Meng, Cheong, Wei Yang, Thien, Kwee Eng, Goh, Khean Teik, Chai, Jin-Fang, Lee, Jimmy, Sung, Joseph Jao-Yiu, Wong, Tien Yin, Chin, Calvin Woon Loong, Gluckman, Peter D., Goh, Liuh Ling, Ban, Kenneth Hon Kim, Tan, Tin Wee, Sim, Xueling, Cheng, Ching-Yu, Davila, Sonia, Karnani, Neerja, Leong, Khai Pang, Liu, Jianjun, Prabhakar, Shyam, Maurer-Stroh, Sebastian, Verma, Chandra Shekhar, Krishnaswamy, Pavitra, Goh, Rick Siow Mong, Chia, Irenaeus, Ho, Clarissa, Low, Doreen, Virabhak, Suchin, Yong, Jacklyn, Zheng, Weiling, Seow, Shih Wee, Seck, Yee Kwang, Koh, Mingshi, Chambers, John C., Tai, E. Shyong, and Tan, Patrick

Published
2023
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16. The Intersection between Leadership and Identity: Managing as a Counseling Center Director of Color

Author

Chin, Calvin R., Singleton, Karen, and Juarez, Reina

Abstract

Directors of color at college counseling centers face many challenges. In this article, three directors of color will describe the issues they face on a daily basis working in predominantly white institutions to illustrate how racial identities intersect with leadership. Included among the dynamics explored are the external pressures of unattainable expectations held by supervisors; microaggressions and negative stereotyping among peers; stereotype threat; and internal pressures around being undermined in racialized ways by staff; and managing projections and over-identifications among staff. We highlight the ways it can feel like walking a tightrope around serving the needs of a diverse staff. The article concludes by offering suggestions and next steps for supervisors of directors of color, staff of directors of color, and directors of color themselves.

Published
2022
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18. Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 that Are Common in Chinese Patients

Author

Pua, Chee Jian, Tham, Nevin, Chin, Calvin WL, Walsh, Roddy, Khor, Chiea Chuen, Toepfer, Christopher N, Repetti, Giuliana G, Garfinkel, Amanda C, Ewoldt, Jourdan F, Cloonan, Paige, Chen, Christopher S, Lim, Shi Qi, Cai, Jiashen, Loo, Li Yang, Kong, Siew Ching, Chiang, Charleston WK, Whiffin, Nicola, de Marvao, Antonio, Lio, Pei Min, Hii, An An, Yang, Cheng Xi, Le, Thu Thao, Bylstra, Yasmin, Lim, Weng Khong, Teo, Jing Xian, Padilha, Kallyandra, Silva, Gabriela V, Pan, Bangfen, Govind, Risha, Buchan, Rachel J, Barton, Paul JR, Tan, Patrick, Foo, Roger, Yip, James WL, Wong, Raymond CC, Chan, Wan Xian, Pereira, Alexandre C, Tang, Hak Chiaw, Jamuar, Saumya Shekhar, Ware, James S, Seidman, Jonathan G, Seidman, Christine E, and Cook, Stuart A

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Genetics, Cardiovascular, Clinical Research, Heart Disease, 2.1 Biological and endogenous factors, Aetiology, Asian People, Cardiomyopathy, Hypertrophic, China, Female, Gene Frequency, Genetic Association Studies, Haplotypes, Heart Ventricles, Heterozygote, Humans, Male, Middle Aged, Odds Ratio, Polymorphism, Single Nucleotide, Risk, Singapore, Troponin I, Troponin T, cardiomyopathies, hypertrophy, population, troponin I, troponin T, Medical Biotechnology, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology
Abstract

BackgroundTo assess the genetic architecture of hypertrophic cardiomyopathy (HCM) in patients of predominantly Chinese ancestry.MethodsWe sequenced HCM disease genes in Singaporean patients (n=224) and Singaporean controls (n=3634), compared findings with additional populations and White HCM cohorts (n=6179), and performed in vitro functional studies.ResultsSingaporean HCM patients had significantly fewer confidently interpreted HCM disease variants (pathogenic/likely pathogenic: 18%, P

Published
2020

22. Circulating Plasma Proteins in Aortic Stenosis: Associations With Severity, Myocardial Response, and Clinical Outcomes.

Author

Tan, Eugene S. J., Hyungwon Choi, DeFilippi, Christopher R., Yen-Yee Oon, Siew-Pang Chan, Gong, Lingli, Lunaria, Josephine B., Oi-Wah Liew, Pek-Ching Chong, Jenny, Lik-Wui Tay, Edgar, Wern-Miin Soo, Wei-Luen Yip, James, Quek Wei Yong, Lee, Evelyn Min, Yeo, Poh Shuan Daniel, Zee Pin Ding, Hak Chiaw Tang, See Hooi Ewe, Chin, Calvin W. L., and Siang Chew Chai

Published
2024
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27. Markers of Myocardial Damage Predict Mortality in Patients With Aortic Stenosis

Author

Kwak, Soongu, Everett, Russell J., Treibel, Thomas A., Yang, Seokhun, Hwang, Doyeon, Ko, Taehoon, Williams, Michelle C., Bing, Rong, Singh, Trisha, Joshi, Shruti, Lee, Heesun, Lee, Whal, Kim, Yong-Jin, Chin, Calvin W.L., Fukui, Miho, Al Musa, Tarique, Rigolli, Marzia, Singh, Anvesha, Tastet, Lionel, Dobson, Laura E., Wiesemann, Stephanie, Ferreira, Vanessa M., Captur, Gabriella, Lee, Sahmin, Schulz-Menger, Jeanette, Schelbert, Erik B., Clavel, Marie-Annick, Park, Sung-Ji, Rheude, Tobias, Hadamitzky, Martin, Gerber, Bernhard L., Newby, David E., Myerson, Saul G., Pibarot, Phillipe, Cavalcante, João L., McCann, Gerry P., Greenwood, John P., Moon, James C., Dweck, Marc R., and Lee, Seung-Pyo

Published
2021
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28. Cardiovascular Magnetic Resonance Reference Ranges From the Healthy Hearts Consortium

Author

MS Radiologie, Raisi-Estabragh, Zahra, Szabo, Liliana, McCracken, Celeste, Bülow, Robin, Aquaro, Giovanni Donato, Andre, Florian, Le, Thu Thao, Suchá, Dominika, Condurache, Dorina Gabriela, Salih, Ahmed M., Chadalavada, Sucharitha, Aung, Nay, Lee, Aaron Mark, Harvey, Nicholas C., Leiner, Tim, Chin, Calvin W.L., Friedrich, Matthias G., Barison, Andrea, Dörr, Marcus, Petersen, Steffen E., MS Radiologie, Raisi-Estabragh, Zahra, Szabo, Liliana, McCracken, Celeste, Bülow, Robin, Aquaro, Giovanni Donato, Andre, Florian, Le, Thu Thao, Suchá, Dominika, Condurache, Dorina Gabriela, Salih, Ahmed M., Chadalavada, Sucharitha, Aung, Nay, Lee, Aaron Mark, Harvey, Nicholas C., Leiner, Tim, Chin, Calvin W.L., Friedrich, Matthias G., Barison, Andrea, Dörr, Marcus, and Petersen, Steffen E.

Published
2024

30. Biomarkers in the evaluation of cardiac involvement in systemic sclerosis.

Author

Masri, Mohamad Fadhli Bin, Ng, Sue-Ann, Chin, Calvin WL, and Low, Andrea HL

Subjects
SYSTEMIC scleroderma, BIOMARKERS
Abstract

Systemic sclerosis is a multisystemic disease for which the heart can be affected leading to cardiac complications and mortality. Up to 80% of patients with systemic sclerosis have cardiac involvement with varying levels of severity. Several molecules have been identified that can be used as markers of cardiac involvement. These biomarkers can arise directly from the heart due to cardiac damage from the disease such as cardiac troponins or from the underlying dysregulated immune process itself such as the proinflammatory cytokines including interleukin (IL)-6. This review aims to summarize the evidence on currently known biomarkers that are can be diagnostic, prognostic or predictive of primary cardiac involvement in systemic sclerosis. We also highlight potential new biomarkers based on the current understanding of the disease process. Clinical use of these markers can benefit patients through earlier identification of those with cardiac involvement, many of whom can be asymptomatic in the early stage, with higher risk of complications, with the overall goal to improve outcomes of these affected patients. [ABSTRACT FROM AUTHOR]

Published
2024
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33. A Genotype-phenotype Taxonomy of Hypertrophic Cardiomyopathy

Author

Curran, Lara, primary, Marvao, Antonio De, additional, Inglese, Paolo, additional, McGurk, Kathryn, additional, Clement, Adam, additional, Zheng, Sean, additional, Li, Surui, additional, Pua, Chee Jian, additional, Shah, Mit, additional, Jafari, Mina, additional, Theotokis, Pantazis, additional, Buchan, Rachel, additional, Jurgens, Sean, additional, Raphael, Claire, additional, Baksi, John, additional, Pantazis, Antonis, additional, Halliday, Brian, additional, Pennell, Dudley, additional, Bai, Wenjia, additional, Chin, Calvin, additional, Tadros, Rafik, additional, Bezzina, Connie, additional, Watkins, Hugh, additional, Cook, Stuart, additional, Prasad, Sanjay, additional, Ware, James, additional, and O'Regan, Declan, additional

Published
2024
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34. Cardiovascular Magnetic Resonance Reference Ranges FBom the Healthy Hearts Consortium

Author

Raisi-Estabragh, Zahra, primary, Szabo, Liliana, additional, McCracken, Celeste, additional, Bülow, Robin, additional, Aquaro, Giovanni Donato, additional, André, Florian, additional, Le, Thu-Thao, additional, Sucha, Dominika, additional, Condurache, Dorina, additional, Salih, Ahmed, additional, Aung, Nay, additional, Lee, Aaron, additional, Harvey, Nicholas, additional, Leiner, Tim, additional, Chin, Calvin Woon Loong, additional, Friedrich, Matthias Gero, additional, Barison, Andrea, additional, Dorr, Marcus, additional, and Petersen, Steffen, additional

Published
2024
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38. Assessment and risk prediction in patients with aortic stenosis : insights from cardiovascular magnetic resonance

Author

Chin, Calvin Woon Loong, Newby, David, and Dweck, Marc

Subjects
616.1, aortic stenosis, cardiovascular magnetic resonance, myocardial fibrosis, decompensation
Abstract

BACKGROUND Aortic stenosis affects not only the valve but also the myocardium. In response to the increased afterload, left ventricular hypertrophy initially occurs as a compensatory response to maintain wall stress and cardiac output but ultimately, decompensation and heart failure ensues. The transition from adaptation to decompensation is driven by myocyte death and myocardial fibrosis. The aims of the thesis are to investigate cardiovascular magnetic resonance assessment of disease severity and myocardial fibrosis, and explore its relationship with other biomarkers of disease activity and clinical outcome in patients with aortic stenosis. METHODS AND RESULTS The conventional assessment of aortic stenosis relies heavily on two-dimensional and Doppler echocardiography but there are inherent limitations in echocardiography that can affect the severity classification. I demonstrated that cardiovascular magnetic resonance offered a more accurate estimation of left ventricular volumes and mass, and excellent myocardial characterization. Indeed, inaccurate stroke volume estimation by Doppler echocardiography and inconsistent thresholds in current guidelines accounted for more than 40% of patients with discordant small-area, lowgradient aortic stenosis. These data may explain the variable prognosis reported in this unique group of patients, and argue for more accurate assessment of borderline cases with cardiovascular magnetic resonance. Late gadolinium enhancement imaging detects focal areas of established myocardial fibrosis. In many conditions, including aortic stenosis, a more diffuse form of fibrosis predominates, which is potentially reversible and not readily identified by late gadolinium enhancement. Recently several myocardial T1 mapping approaches have been developed to quantify diffuse fibrosis. Using a standardized and systematic approach, I compared several commonly used T1 mapping techniques and identified that extracellular volume had the best profile (reproducibility and discriminatory potential) for the identification of diffuse fibrosis in patients with aortic stenosis. Cardiac troponin is a structural protein present in the cardiac myocytes. Recent advances in assay technology have substantially improved sensitivity, allowing quantification of troponin concentrations with a high degree of precision in everyone. In more than 250 patients with aortic stenosis, I demonstrated that cardiac troponin I concentrations were independently associated with markers of left ventricular decompensation (hypertrophy and fibrosis) and predicted clinical outcome in patients with aortic stenosis. This suggests that myocardial fibrosis detected by cardiovascular magnetic resonance is consequent on myocardial injury secondary to left ventricular decompensation. Left ventricular hypertrophy with strain pattern on a 12-lead electrocardiogram is associated with poor outcome in patients with aortic stenosis, but the mechanism of this electrocardiographic pattern has not been described. In more than 300 patients with aortic stenosis, I demonstrated that these characteristic repolarization abnormalities were a highly specific marker of focal mid-wall myocardial fibrosis (specificity of 99% and sensitivity of 54%). Moreover, the prognostic value of this electrocardiographic pattern was again confirmed with markedly worse long-term outcomes in these patients. CONCLUSION I have demonstrated that cardiovascular magnetic resonance can assist in the assessment of disease severity in patients with aortic stenosis and discordant echocardiographic findings. Moreover, I have validated the assessment of diffuse myocardial fibrosis, as well as, demonstrated the close association between myocardial fibrosis and biomarkers of myocardial injury and electrocardiographic strain pattern that predicted an adverse outcome in patients with aortic stenosis.

Published
2015

40. A novel cardiovascular magnetic resonance risk score for predicting mortality following surgical aortic valve replacement

Author

Vassiliou, Vassilios S., Pavlou, Menelaos, Malley, Tamir, Halliday, Brian P., Tsampasian, Vasiliki, Raphael, Claire E., Tse, Gary, Vieira, Miguel Silva, Auger, Dominique, Everett, Russell, Chin, Calvin, Alpendurada, Francisco, Pepper, John, Pennell, Dudley J., Newby, David E., Jabbour, Andrew, Dweck, Marc R., and Prasad, Sanjay K.

Published
2021
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45. Effect of Cangrelor on Infarct Size in ST-Segment–Elevation Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention: A Randomized Controlled Trial (The PITRI Trial)

Author

Bulluck, Heerajnarain, Chong, Jun Hua, Bryant, Jennifer, Annathurai, Annitha, Chai, Ping, Chan, Mervyn, Chawla, Ashish, Chin, Chee Yang, Chung, Yiu-Cho, Gao, Fei, Ho, Hee Hwa, Ho, Andrew Fu Wah, Hoe, John, Imran, Syed Saqib, Lee, Chi-Hang, Lim, Benji, Lim, Soo Teik, Lim, Swee Han, Liew, Boon Wah, Zhan Yun, Patrick Lim, Ong, Marcus Eng Hock, Paradies, Valeria, Pung, Xuan Ming, Tay, Julian Cheong Kiat, Teo, Lynette, Ting, Boon Ping, Wong, Aaron, Wong, Evelyn, Watson, Timothy, Chan, Mark Y., Keong, Yeo Khung, Tan, Jack W.C., Hausenloy, Derek J., Tan, Jack W.C., Hausenloy, Derek J., Chi, Chee-Tang, Tay, Julian, Xuan Ming, Pung, Anbalakan, Kamalesh, Yann San, Keh, Chew, Kenneth, Chan, Michelle, Rilong, Hong, Swee Leng, Kui, Soo Teik, Lim, Lee, Audry, Maverick Rubillar, Felix, Cai, James, Yap, Jonathan, Ning Yan, Wong, Kay Woon, Ho, Fang Yi, Lim, Xia Yen, Shen, Xucong, Ruan, Khung Keong, Yeo, Hua Chong, Jun, Bryant, Jennifer, Chua, Terrance, Yang Chin, Chee, Paradies, Valeria, Wong, Aaron, Bahru, Leong, Teo, Tina, Ru San, Tan, Hak Chiaw, Tang, Chin, Calvin, Ang, Florence, Kyaw, Min-Tun, Priyalatha, S., Chua, Jia-Mei, Yip, Deborah, Lee, Rosalind, Oh, Katherina, Pei Yi, Ho, Wanshan, Leow, Atiqa Binte Rahmat, Syamimi, Yar Chze, Gan, Hausenloy, Derek J., Gao, Fei, Yan Tan, Shi, Chan, Mervyn, Fatimah, Lateef, Ho, Andrew, Choon Peng Jeffrey, Wee, Han Lim, Swee, Ong Eng Hock, Marcus, Wong, Evelyn, Tan Boon Kiat, Kenneth, Venkataraman, Anantharaman, Chan, Mark Y., Lee, Chi-Hang, Ping, Chai, Fatt Hoe Adrian, Low, Koo Hui, Chan, Poay Huan, Loh, Yi-Ting Laureen, Wang, Zhengfeng Jason, Chen, Dalakoti, Mayank, Ng, Perryn, Ching Hui, Sia, Chook, Shaun, Yip, Alfred, Zhe Yan, Ng, Hartanto Djohan, Andie, Houdmont, Marie, Chew, Nicholas, Jiamin, Siew, Ng, Faclin, Teo, Lynette, Ching Ong, Ching, Song, Junda, Kuang Low, Choong, Shalini, Nair, Francis Prabath, Joseph, Ho, Hee-Hwa, Mahadi, Tasha, Watson, Timothy, Ong, Paul, Xin Ni, Koo, Chai Jun Hui, Tony, Yue Ting, Ho, Zhi Lin Deanna, Khoo, Lee Jin Hyun, Deborah, Ki Fung Cliff, Li, Low Jun Bang, Randal, Joo Hor, Tan, Ke Xuan Jessica, Ng, Jia Min, Chua, Wei Sheng Jonathan, Ong, Xuyan, Teoh, Shu Qi Benita, Chiang, Sim Wen Jun, Eran, An Shing, Ang, Jia-ling Stephanie, Quek, Rui Yi, Pang, Ahmad Hatib Muhammad Alimi, Bin, Jin Hyun, Lee, Shiane, Lim, Chong Keat, Tan, Shonda, Ng, Hoe, John, Tan, Jack, Chee Yang, Chin, Jian Ming, Fam, Raudha, Siti, Annathurai, Annitha, Ping Ting, Boon, Chawla, Ashish, Saqib Imran, Syed, Lim Zhan Yun, Patrick, Tan, Alvin, Lim, Benji, Wah Liew, Boon, and Thon Hon, Yong

Published
2024
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46. Genotype-Phenotype Taxonomy of Hypertrophic Cardiomyopathy

Author

Curran, Lara, primary, de Marvao, Antonio, additional, Inglese, Paolo, additional, McGurk, Kathryn A., additional, Schiratti, Pierre-Raphaël, additional, Clement, Adam, additional, Zheng, Sean L., additional, Li, Surui, additional, Pua, Chee Jian, additional, Shah, Mit, additional, Jafari, Mina, additional, Theotokis, Pantazis, additional, Buchan, Rachel J., additional, Jurgens, Sean J., additional, Raphael, Claire E., additional, Baksi, Arun John, additional, Pantazis, Antonis, additional, Halliday, Brian P., additional, Pennell, Dudley J., additional, Bai, Wenjia, additional, Chin, Calvin W.L., additional, Tadros, Rafik, additional, Bezzina, Connie R., additional, Watkins, Hugh, additional, Cook, Stuart A., additional, Prasad, Sanjay K., additional, Ware, James S., additional, and O’Regan, Declan P., additional

Published
2023
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48. Exaggerated elastin turnover in young individuals with Marfan syndrome: new insights from the AIMS trial

Author

Iskandar, Zaid, primary, Dodd, Matthew, additional, Huang, Jeffrey, additional, Chin, Calvin W L, additional, Stuart, Graham, additional, Caputo, Massimo, additional, Clayton, Tim, additional, Child, Anne, additional, Jin, Xu Yu, additional, Aragon-Martin, José Antonio, additional, Gibb, Jack, additional, Flather, Marcus, additional, and Choy, Anna-Maria, additional

Published
2023
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49. Sacubitril/valsartan versus valsartan in regressing myocardial fibrosis in hypertension: a prospective, randomized, open-label, blinded endpoint clinical trial protocol

Author

Lee, Vivian, primary, Zheng, Qishi, additional, Toh, Desiree-Faye, additional, Pua, Chee Jian, additional, Bryant, Jennifer A., additional, Lee, Chi-Hang, additional, Cook, Stuart A., additional, Butler, Javed, additional, Díez, Javier, additional, Richards, A. Mark, additional, Le, Thu-Thao, additional, and Chin, Calvin W. L., additional

Published
2023
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