40 results on '"Chillcott S"'
Search Results
2. Family Participation in Daily ECMO Rounds
- Author
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Stahovich, M., primary, Lerum, S., additional, Price, R., additional, Chillcott, S., additional, Adamson, R., additional, and Dembitsky, W., additional
- Published
- 2018
- Full Text
- View/download PDF
3. A 7 Center Review of Left Ventricular Assist Device (LVAD) Caregiver Perceptions
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Schettle, S., primary, Staley, L., additional, Schroeder, S., additional, Luckhardt, A., additional, Chillcott, S., additional, Kasper, M., additional, Bjelkengren, J., additional, Marchand, C., additional, Stulak, J., additional, and Dunlay, S., additional
- Published
- 2016
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4. (458) - Family Participation in Daily ECMO Rounds
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Stahovich, M., Lerum, S., Price, R., Chillcott, S., Adamson, R., and Dembitsky, W.
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- 2018
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5. 752 Should Advanced Age Be a Contra-Indication to LVAD Implant: A Community Hospital Experience
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Adamson, R.M., primary, Hoagland, P., additional, Jaski, B., additional, Stahovich, M., additional, Chillcott, S., additional, and Dembitsky, W.P., additional
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- 2012
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6. 552 Are LVAD Support and Cardiac Transplantation Approaching Equipoise?
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Adamson, R.M., primary, Jaski, B., additional, Hoagland, P., additional, Chammas, J., additional, Norman, V., additional, McCalmont, V., additional, Hazard, L., additional, Ortiz, K., additional, Chillcott, S., additional, Stahovich, M., additional, and Dembitsky, W.P., additional
- Published
- 2012
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7. 756 Can Right Ventricular Failure Associated with LVAD Insertion Be Avoided?
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Adamson, R.M., primary, Chammas, J., additional, Norman, V., additional, Jaski, B., additional, Hoagland, P., additional, Chillcott, S., additional, Stahovich, M., additional, and Dembitsky, W.P., additional
- Published
- 2012
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8. 164 Cost Comparison of HeartMate II Implantation and Cardiac Transplantation
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Adamson, R.M., primary, Jaski, B., additional, Hoagland, P., additional, Baradarian, S., additional, Chammas, J., additional, Norman, V., additional, Chillcott, S., additional, Stahovich, M., additional, Ortiz, K., additional, McCalmont, V., additional, Hazard, L., additional, and Dembitsky, W.P., additional
- Published
- 2011
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9. 481 Clinical Importance of Aortic Valve Deterioration during HeartMate II Support
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Adamson, R.M., primary, Dembitsky, W.P., additional, Baradarian, S., additional, Chammas, J., additional, Norman, V., additional, Hoagland, P., additional, Stahovich, M., additional, Chillcott, S., additional, and Jaski, B., additional
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- 2011
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10. 138: Neurocognitive Evaluation of Destination Therapy Pateints Receiving Continuous Flow Left Ventricular Assist Devices
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Petrucci, R.J., primary, Rogers, J.G., additional, Blue, L., additional, Gallagher, C.T., additional, Russell, S.D., additional, Dordunoo, D., additional, Jaski, B.E., additional, Chillcott, S., additional, Sun, B.C., additional, and Yanssens, T.L., additional
- Published
- 2010
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11. 412: Twenty-Five Patients with Aortic Valve Closure Associated with HeartMate LVAD Insertion
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Adamson, R.M., primary, Dembitsky, W.P., additional, Baradarian, S., additional, Chammas, J., additional, Jaski, B., additional, Hoagland, P., additional, Chillcott, S., additional, Stahovich, M., additional, McCalmont, V., additional, and Ortiz, K., additional
- Published
- 2009
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12. 413: Outcomes of Patients over 70 Receiving Left Ventricular Assist Devices
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Stahovich, M., primary, Chillcott, S., additional, Adamson, R., additional, Baradarian, S., additional, Chammus, J., additional, Jaski, B., additional, Hoagland, P., additional, and Dembitsky, W., additional
- Published
- 2009
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- View/download PDF
13. 39: Tricuspid Valve Replacement Coincident with HeartMate LVAD Insertion
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Adamson, R.M., primary, Dembitsky, W.P., additional, Chammas, J., additional, Baradarian, S., additional, Hoagland, P., additional, Jaski, B., additional, Stahovich, M., additional, Chillcott, S., additional, Ortiz, K., additional, and McCalmont, V., additional
- Published
- 2009
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14. Change in physical and psychosocial domains of quality of life from before to after discharge post left ventricular assist device implantation
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Grady, K.L., primary, Meyer, P., additional, Mattea, A., additional, Dressler, D., additional, Ormaza, S., additional, White-Williams, C., additional, Chillcott, S., additional, Kaan, A., additional, Loo, A., additional, Todd, B., additional, Klemme, A., additional, Piccione, W., additional, and Costanzo, M., additional
- Published
- 2001
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15. CHRONIC LEFT VENTRICULAR ASSIST DEVICE (LVAD) BRIDGE TO TRANSPLANT WITH LEFT VENTRICULAR OUTFLOW (LVOT) OBSTRUCTION CLINICAL RESULTS
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Dembitsky, W P, primary, Jaski, B E, additional, Adamson, R M, additional, Chillcott, S R, additional, and Daily, P O, additional
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- 2000
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16. ECCO2R: an experimental approach to treating ARDS
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Chillcott, S, primary and Sheridan, PS, additional
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- 1995
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17. Mental health and medical challenges: management of a depressed patient with a left ventricular assist system in an inpatient psychiatric setting.
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Tylus-Earl N and Chillcott S
- Abstract
A depressed patient with a left ventricular assist device (LVAD) due to heart failure presented a unique challenge for staff in an inpatient psychiatric facility. Although depression in this patient population has been recognized and treated on an outpatient basis, the example described in this article may be the first known case to be treated in an acute inpatient psychiatric hospital setting. A variety of steps had to be taken to ensure the highest standards of care, as well as an optimal outcome for this patient. In addition to the individualized plan of care for depression, a more medically oriented and technologically advanced plan of care was also instituted. The inpatient psychiatric setting provides the necessary care and treatment to help the patient move beyond severe depression to engage in activities essential for health and the proper care and function of the LVAD. This article highlights an unusual psychiatric-mental health nursing situation to help others who may face this challenge in the future. [ABSTRACT FROM AUTHOR]
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- 2009
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18. Portable rapid response extracorporeal life support: a center's 20-year experience with a registered nurse--run program.
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Chillcott S, Stahovich M, Earnhardt C, and Dembitsky W
- Abstract
If advanced cardiac life support therapy fails to revive a patient, extracorporeal life support (ECLS) becomes a critical bridge that maintains total systemic circulation and oxygenation during cardiac arrest or severe respiratory failure and allows time to establish a treatment plan. Improved patient outcomes depend on a shorter time period from the start of advanced cardiac life support to the initiation of ECLS. An in-house critical care nurse response team facilitates rapid initiation of ECLS, often in less than 20 minutes, at any time in any area of the hospital. Since 1986, Sharp Memorial Hospital has placed 176 patients on ECLS, using a registered nurse team with a survival rate greater than 30 days of 27.7%. The system used for rapid and mobile initiation of ECLS maintains perfusion to the vital organs via a centrifugal flow pump, using a hollow-fiber membrane oxygenator and percutaneous cannulas. Team members prime the system while the ECLS-trained first-response physicians place cannulae. All elements of program development, team education, and ongoing program maintenance are critical to successful outcomes for patients. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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19. The next treatment option: using ventricular assist devices for heart failure.
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Stahovich M, Chillcott S, and Dembitsky WP
- Abstract
Ventricular assist devices (VADs) are becoming more commonplace in the hospital and community settings as the number of patients living with heart failure increases. Patients being discharged after hospitalization for heart failure rose from 399 000 in 1979 to 1 099 000 in 2004, an increase of 175%. Patients with heart failure become severely debilitated finding activities of daily living including eating, bathing, and walking a great effort. Patients with end-stage heart failure are often sent home on inotropic therapies and referred to hospice care. The use of VADs for these patients can dramatically improve both the quality and the length of life. VADs can be broadly categorized as being either continuous flow (fluid dynamic) or pulsatile (volume displacement) and either can be used as short- or long-term support devices. The critical care nurse is in a unique position to educate patients with chronic heart failure on options available to improve their quality of life including VAD therapy. VADs are available for destination therapy for those not meeting transplant criteria, offering a longer quality of life. As centers gain more experience and referrals are made earlier in the disease process, VAD patient care will be more streamlined decreasing length of stay. [ABSTRACT FROM AUTHOR]
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- 2007
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20. Improvement in quality of life outcomes 2 weeks after left ventricular assist device implantation
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Grady, K. L., Meyer, P., Mattea, A., White-Williams, C., Ormaza, S., Kaan, A., Todd, B., Chillcott, S., Dressler, D., and Fu, A.
- Published
- 2001
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21. Clinical Strategies and Outcomes in Advanced Heart Failure Patients Older Than 70 Years of Age Receiving the HeartMate II Left Ventricular Assist Device A Community Hospital Experience.
- Author
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Adamson RM, Stahovich M, Chillcott S, Baradarian S, Chammas J, Jaski B, Hoagland P, and Dembitsky W
- Published
- 2011
- Full Text
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22. (959) - A 7 Center Review of Left Ventricular Assist Device (LVAD) Caregiver Perceptions.
- Author
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Schettle, S., Staley, L., Schroeder, S., Luckhardt, A., Chillcott, S., Kasper, M., Bjelkengren, J., Marchand, C., Stulak, J., and Dunlay, S.
- Subjects
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HEART assist devices , *HEART transplant recipients , *PSYCHOLOGICAL stress , *HEALTH education , *SENSORY perception - Published
- 2016
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23. Evaluating qualitative data analysis workshops from the perspective of public contributors.
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Moult A, McGrath C, Lippiett K, Coope C, Turner A, Chillcott S, Parton L, Holloway P, Dace S, Gibson A, Jinks C, Paskins Z, Portillo MC, Mann C, and Dziedzic K
- Abstract
Background: The aim of this project is to evaluate public contributors' experiences of their involvement in qualitative data analysis workshops during an on-going research project titled 'Personalised Primary care for Patients with Multiple long-term conditions'., Methods: Four qualitative data analysis workshops were designed and conducted between August and December 2023. We used the Cube evaluation framework (henceforth referred to as the Cube) to evaluate the workshops. The Cube suggests four domains for successful PPI (voice, agenda, change, contribute).Within Workshops One, Two and Three public contributors had to login to an account to access the Cube; this was modified in Workshop Four following feedback from public contributors., Findings: Across the four workshops the Cube was completed 11 times. Across all four workshops, public contributors thought that their voice was heard, that there were diverse ways to contribute and that they led the agenda. Public contributors thought that researchers responded to their questions and issues, when necessary., Conclusion: This evaluation has shown that public contributors can gain new skills and lead qualitative data analysis discussions., (© 2024. The Author(s).)
- Published
- 2024
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24. Chest compressions may be safe in arresting patients with left ventricular assist devices (LVADs).
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Shinar Z, Bellezzo J, Stahovich M, Cheskes S, Chillcott S, and Dembitsky W
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- Aged, Aged, 80 and over, Autopsy, Female, Humans, Male, Middle Aged, Retrospective Studies, Treatment Outcome, Heart Arrest therapy, Heart Massage adverse effects, Heart-Assist Devices, Out-of-Hospital Cardiac Arrest therapy
- Abstract
Introduction: The number of patients with left ventricular assist devices (LVADs) is increasing each year. Despite a lack of evidence, many emergency medical systems and hospitals have recommended against performing chest compressions in these patients. This deviation from conventional resuscitation algorithms is secondary to concern that chest compressions could dislodge the LVAD., Objective: To assess whether cannula dislodgment occurred in LVAD patients receiving chest compressions., Methods: We retrospectively analyzed the outcomes of all LVAD patients who received chest compressions for cardiac arrest over a four year period in a large urban hospital. Eight cases were reviewed for both cannula integrity and outcomes., Results: Using autopsy and adequate flow through device as proxy for intact inflow/outflow cannulas, none of the eight patients receiving chest compressions had cannula dislodgment. Four of the 8 patients had return of neurologic function., Conclusions: In this small retrospective case series, standard chest compressions in patients with LVADs did not cause cannula dislodgment. More research is necessary to determine the utility of chest compressions in the LVAD population., (Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.)
- Published
- 2014
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25. Emergency physician-initiated extracorporeal cardiopulmonary resuscitation.
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Bellezzo JM, Shinar Z, Davis DP, Jaski BE, Chillcott S, Stahovich M, Walker C, Baradarian S, and Dembitsky W
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- Aged, Emergency Service, Hospital, Female, Heart Arrest mortality, Humans, Male, Middle Aged, Observation, Patient Discharge, Retrospective Studies, Algorithms, Cardiopulmonary Bypass, Cardiopulmonary Resuscitation methods, Emergency Medicine, Heart Arrest therapy
- Abstract
Context: Extracorporeal cardiopulmonary resuscitation (ECPR) refers to emergent percutaneous veno-arterial cardiopulmonary bypass to stabilize and provide temporary support of patients who suffer cardiopulmonary arrest. Initiation of ECPR by emergency physicians with meaningful long-term patient survival has not been demonstrated., Objective: To determine whether emergency physicians could successfully incorporate ECPR into the resuscitation of patients who present to the emergency department (ED) with cardiopulmonary collapse refractory to traditional resuscitative efforts., Design: A three-stage algorithm was developed for ED ECPR in patients meeting inclusion/exclusion criteria. We report a case series describing our experience with this algorithm over a 1-year period., Results: 42 patients presented to our ED with cardiopulmonary collapse over the 1-year study period. Of these, 18 patients met inclusion/exclusion criteria for the algorithm. 8 patients were admitted to the hospital after successful ED ECPR and 5 of those patients survived to hospital discharge neurologically intact. 10 patients were not started on bypass support because either their clinical conditions improved or resuscitative efforts were terminated., Conclusion: Emergency physicians can successfully incorporate ED ECPR in the resuscitation of patients who suffer acute cardiopulmonary collapse. More studies are necessary to determine the true efficacy of this therapy., (Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.)
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- 2012
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26. Neurocognitive function in destination therapy patients receiving continuous-flow vs pulsatile-flow left ventricular assist device support.
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Petrucci RJ, Rogers JG, Blue L, Gallagher C, Russell SD, Dordunoo D, Jaski BE, Chillcott S, Sun B, Yanssens TL, Tatooles A, Koundakjian L, Farrar DJ, and Slaughter MS
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- Adult, Aged, Female, Follow-Up Studies, Heart Failure physiopathology, Heart Failure psychology, Humans, Male, Memory physiology, Middle Aged, Prosthesis Design, Treatment Outcome, Cognition physiology, Heart Failure therapy, Heart Transplantation, Heart-Assist Devices
- Abstract
Background: The HeartMate II (Thoratec Corp, Pleasanton, CA) continuous-flow left ventricular assist device (LVAD) improved survival in destination therapy (DT) patients during a randomized trial compared with pulsatile-flow LVADs. This study documented changes in cognitive performance in DT patients from that trial to determine if there were differences between continuous-flow and pulsatile-flow support., Methods: Data were collected in a sub-study from 96 HeartMate II continuous-flow and 30 HeartMate XVE pulsatile-flow LVAD patients from 12 of the 35 trial sites that followed the same serial neurocognitive (NC) testing protocol at 1, 3, 6, 12, and 24 months after LVAD implantation. Spatial perception, memory, language, executive functions, and processing speed were the domains assessed with 10 standard cognitive measures. Differences over time and between LVAD type were evaluated with linear mixed-effects modeling., Results: From 1 to 24 months after LVAD implantation, changes in NC functions were stable or showed improvement in all domains, and there were no differences between the continuous-flow and pulsatile-flow groups. Data at 24 months were only available from patients with the continuous-flow LVAD due to the limited durability of the HeartMate XVE device. There was no decline in any NC domain over the time of LVAD support. Missing data not collected from patients who died could have resulted in a bias toward inflated study results., Conclusions: The NC performance of advanced heart failure patients supported with continuous-flow and pulsatile-flow LVADs shows stabilization or improvement during support for up to 24 months., (Copyright © 2012 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.)
- Published
- 2012
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27. Aortic valve closure associated with HeartMate left ventricular device support: technical considerations and long-term results.
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Adamson RM, Dembitsky WP, Baradarian S, Chammas J, May-Newman K, Chillcott S, Stahovich M, McCalmont V, Ortiz K, Hoagland P, and Jaski B
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- Adolescent, Adult, Aged, Aged, 80 and over, Aortic Valve Insufficiency epidemiology, Cardiac Surgical Procedures mortality, Equipment Failure, Female, Heart Valve Prosthesis, Humans, Incidence, Kaplan-Meier Estimate, Longitudinal Studies, Male, Middle Aged, Retrospective Studies, Young Adult, Aortic Valve surgery, Aortic Valve Insufficiency surgery, Cardiac Surgical Procedures methods, Heart-Assist Devices
- Abstract
Background: Aortic valve integrity is crucial for optimal left ventricular assist device (LVAD) support. Pre-existing native aortic insufficiency, aortic valve incompetence acquired during support, as well as previously placed prosthetic aortic valves present unique problems for these patients., Methods: We reviewed and analyzed data for 28 patients who underwent left ventricular outflow tract closure associated with HeartMate I (n =12) and HeartMate II (n = 16) LVAD insertion or exchange. Indications for valve closure, surgical technique, LVAD function, survival rates and complications were retrospectively analyzed. Survival rates were compared with those of HeartMate LVAD patients (n = 104) who did not undergo aortic valve closure., Results: Indications for closure included native aortic valve insufficiency (10 patients), aortic valve deterioration after prolonged LVAD support (8 patients) and previously placed mechanical (9 patients) or bioprosthetic aortic prostheses (1 patient). There were 2 operative and 5 late deaths (mean 227 days post-operatively). Of the deaths, none were due to aortic valve closure. Actuarial survival was 78% at 1 year and 53% at 3 years, which was statistically better than for our patients with an intact aortic outflow (61% at 1 year, 45% at 3 years; p < 0.05). Five patients had transplants, 1 patient was successfully bridged to recovery, and 15 patients remain on LVAD support. No patient with outflow closure developed regurgitation, embolization or compromised LVAD support., Conclusion: Outflow tract closure in LVAD-supported patients is safe, often necessary and well tolerated., (Copyright © 2011 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.)
- Published
- 2011
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28. Clinical management of continuous-flow left ventricular assist devices in advanced heart failure.
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Slaughter MS, Pagani FD, Rogers JG, Miller LW, Sun B, Russell SD, Starling RC, Chen L, Boyle AJ, Chillcott S, Adamson RM, Blood MS, Camacho MT, Idrissi KA, Petty M, Sobieski M, Wright S, Myers TJ, and Farrar DJ
- Subjects
- Clinical Trials as Topic, Humans, Patient Selection, Preoperative Care, Risk Assessment, Heart Failure therapy, Heart-Assist Devices adverse effects
- Abstract
Continuous-flow left ventricular assist devices (LVAD) have emerged as the standard of care for advanced heart failure patients requiring long-term mechanical circulatory support. Evidence-based clinical management of LVAD-supported patients is becoming increasingly important for optimizing outcomes. In this state-of-art review, we propose key elements in managing patients supported with the new continuous-flow LVADs. Although most of the presented information is largely based on investigator experience during the 1,300-patient HeartMate II clinical trial, many of the discussed principles can be applied to other emerging devices as well. Patient selection, pre-operative preparation, and the timing of LVAD implant are some of the most important elements critical to successful circulatory support and are principles universal to all devices. In addition, proper nutrition management and avoidance of infectious complications can significantly affect morbidity and mortality during LVAD support. Optimizing intraoperative and peri-operative care, and the monitoring and treatment of other organ system dysfunction as it relates to LVAD support, are discussed. A multidisciplinary heart failure team must be organized and charged with providing comprehensive care from initial referral until support is terminated. Preparing for hospital discharge requires detailed education for the patient and family or friends, with provisions for emergencies and routine care. Implantation techniques, troubleshooting device problems, and algorithms for outpatient management, including the diagnosis and treatment of related problems associated with the HeartMate II, are discussed as an example of a specific continuous-flow LVAD. Ongoing trials with other continuous-flow devices may produce additional information in the future for improving clinical management of patients with these devices., (Copyright 2010 Elsevier Inc. All rights reserved.)
- Published
- 2010
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29. A 20-year experience with urgent percutaneous cardiopulmonary bypass for salvage of potential survivors of refractory cardiovascular collapse.
- Author
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Jaski BE, Ortiz B, Alla KR, Smith SC Jr, Glaser D, Walsh C, Chillcott S, Stahovich M, Adamson R, and Dembitsky W
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- Female, Heart Arrest mortality, Humans, Male, Middle Aged, Prospective Studies, Survival Rate, Survivors, Time Factors, Cardiopulmonary Bypass methods, Emergency Treatment, Heart Arrest surgery
- Abstract
Objective: In-hospital cardiac arrest or refractory shock carries a high mortality despite the use of advanced resuscitative measures. We have implemented an in-hospital, nurse-based, continuously available, percutaneous, venoarterial cardiopulmonary bypass system, also known as extracorporeal life support (ECLS), as an adjunct to resuscitation when initial measures are ineffective., Methods: In 1986, a system for the rapid initiation of ECLS, was created in which trained critical care nurses primed an ECLS circuit and in-house physicians percutaneously placed required cannulas. From a prospective registry, we assessed long-term survival (LTS) (> or =30 days, cardiopulmonary support weaned), short-term survival (<30 days, CPS weaned), or death on CPS., Results: One hundred fifty patients (age, 57 +/- 17 years) were urgently started on CPS for cardiac arrest (n = 127; witnessed, n = 124; unwitnessed, n = 3) and refractory shock (n = 23). Sixty-nine patients were weaned from CPS, and 81 could not be weaned. Overall, 39 (26.0%) patients achieved LTS with a subsequent Kaplan-Meier median survival of 9.5 years. Duration of CPS was 32 +/- 38 hours for LTS and 21 +/- 38 hours for non-LTS. LTS occurred in 29 (23.4%) of 124 patients started on CPS for witnessed cardiac arrest and 11 (47.8%) of 23 for refractory shock (P < .05). Among patients with CPS initiated in the cardiac catheterization laboratory, LTS was seen in 24 (50.0%) of 48 versus 15 (14.7%) of 102 in patients with CPS initiated in other locations (P < .001). Cardiopulmonary resuscitation times greater than or equal to 30 minutes were associated with lower LTS (P < .05). The most common cause of death during CPS was refractory cardiac dysfunction (39.5%), and the most common cause associated with short-term survival was neurologic/pulmonary dysfunction (53.6%). Seven patients were bridged to a left ventricular assist device, and 1 subsequently underwent heart transplantation. Multivariate analysis revealed only cardiac catheterization laboratory site of initiation as a significant independent predictor of LTS (P < .01). When dividing the 20-year experience in tertiles, recent recipients have had more common prearrest insertion. Rates of long-term survival have not changed., Conclusion: Of patients started on CPS, 46% were weaned, and 26.0% were long-time survivors. Rapid initiation of CPS permits LTS for some inpatients with cardiovascular collapse when initial advanced resuscitation fails. Strategies to improve end-organ function associated with use of CPS should lead to greater LTS. This practical application of inexpensive available technology should be more widely used., (Copyright 2010 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.)
- Published
- 2010
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30. HeartMate left ventricular assist system exchange: results and technical considerations.
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Adamson RM, Dembitsky WP, Baradarian S, Chammas J, Jaski B, Hoagland P, McCalmont V, Ortiz K, Stahovich M, and Chillcott S
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- Adult, Aged, Device Removal statistics & numerical data, Female, Heart Failure mortality, Heart Ventricles, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Time, Cardiovascular Surgical Procedures methods, Device Removal methods, Heart Failure therapy, Heart-Assist Devices
- Abstract
The duration times of left ventricular assist system (LVAS) support have increased because of prolonged wait times for transplant and the more frequent use of devices for destination therapy. The HeartMate LVAS, the only device approved for bridge to transplant and destination therapy, has limited durability, making replacement increasingly necessary. Since 1996, we have exchanged 19 left ventricular assist devices in 15 patients (11 men: mean age, 57.1 years; range, 33-77 years). Most of the devices (14) were replaced with the HeartMate vented electric/extended-lead vented electric pump; five devices were exchanged for a HeartMate II LVAS. Bearing failure was the most frequent reason for exchange (15 of 19 pumps); four of the 19 pumps also had active device-related infections at the time of exchange. There were no early deaths (30 days). Overall survival (Kaplan-Meier) was 85% at 1 year, 67% at 2 years, and 56% at 3 years. Three patients had transplants (mean, 518 days); six patients died during support (mean, 934 days), and six patients remain on LVAS support (mean, 1,219 days). One patient has been on device for over 6 years. Left ventricular assist devices exchange is becoming increasingly likely and can be associated with acceptably low-operative mortality rates and good intermediate-term survival.
- Published
- 2009
- Full Text
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31. Neurocognitive assessments in advanced heart failure patients receiving continuous-flow left ventricular assist devices.
- Author
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Petrucci RJ, Wright S, Naka Y, Idrissi KA, Russell SD, Dordunoo D, Jaski B, Chillcott S, Feldman D, Yanssens T, Heatley G, Koundakjian L, Farrar DJ, and Aaronson KD
- Subjects
- Adolescent, Adult, Aged, Female, Heart Failure physiopathology, Heart Transplantation, Heart Ventricles physiopathology, Humans, Language, Male, Memory physiology, Middle Aged, Prospective Studies, Psychological Tests, Regional Blood Flow physiology, Time Factors, Treatment Outcome, Ventricular Dysfunction, Left physiopathology, Visual Perception physiology, Young Adult, Cognition physiology, Heart Failure psychology, Heart Failure surgery, Heart-Assist Devices adverse effects, Ventricular Dysfunction, Left psychology, Ventricular Dysfunction, Left surgery
- Abstract
Background: Neurocognitive (NC) changes in heart failure patients receiving left ventricular assist devices (LVADs) are not well understood. The purpose of this study was to document changes in the cognitive performance of patients with the continuous-flow HeartMate II LVAD as a bridge to transplant (BTT)., Methods: A NC protocol was used to evaluate patient performance at 1, 3 and 6 months after LVAD implantation at 11 centers. A total of 239 test sessions were completed in 93 patients including paired evaluations in 51 to 57 patients from 1 to 3 months, and in 20 to 28 patients with results from 1, 3 and 6 months. Five NC domains were assessed, including visual spatial perception, auditory and visual memory, executive functions, language and processing speed., Results: There were statistically significant (p < 0.05), but limited improvements between 1, 3 and 6 months in NC domain performances as seen in visual memory, executive functions, visual spatial perception and processing speed. There were no significant declines in any neurocognitive test in any domain over these time periods., Conclusions: The cognitive performance of advanced heart failure patients remained stable or showed slight improvements from Month 1 to Month 6 of continuous-blood-flow support with the HeartMate II LVAD.
- Published
- 2009
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32. Nutrition assessment and management of left ventricular assist device patients.
- Author
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Holdy K, Dembitsky W, Eaton LL, Chillcott S, Stahovich M, Rasmusson B, and Pagani F
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- Cachexia complications, Dietary Carbohydrates administration & dosage, Dietary Fats administration & dosage, Dietary Proteins administration & dosage, Electrolytes administration & dosage, Energy Metabolism, Heart Failure complications, Heart Failure metabolism, Humans, Malnutrition complications, Micronutrients administration & dosage, Obesity complications, Patient Care Team, Preoperative Care, Severity of Illness Index, Heart Failure surgery, Heart-Assist Devices, Nutritional Status, Nutritional Support methods, Postoperative Complications therapy
- Abstract
Nutrition evaluation and support is an integral component of left ventricular assist device (LVAD) therapy. Malnutrition in the LVAD patient contributes to a host of post-operative problems, such as infection and limited functional capacity, which compromise long-term outcomes. Comprehensive pre-operative evaluation of the LVAD patient should include a nutrition assessment and formalized plan to initiate and advance nutrition support while addressing the metabolic imbalances associated with heart failure. An interdisciplinary approach, including a nutrition support team, is desirable to manage these patients effectively. This article reviews essential aspects regarding nutrition management of these patients.
- Published
- 2005
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33. Multicenter experience: prevention and management of left ventricular assist device infections.
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Chinn R, Dembitsky W, Eaton L, Chillcott S, Stahovich M, Rasmusson B, and Pagani F
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- Assisted Circulation economics, Assisted Circulation instrumentation, Assisted Circulation mortality, Bacterial Infections diagnosis, Bacterial Infections therapy, Cost-Benefit Analysis, Humans, Quality of Life, Risk Factors, Surgical Wound Infection etiology, Surgical Wound Infection mortality, Survival Rate, Bacterial Infections complications, Bacterial Infections prevention & control, Heart-Assist Devices microbiology, Multicenter Studies as Topic, Postoperative Complications microbiology
- Abstract
Implantable left ventricular assist devices (LVADs) have demonstrated clinical success in both the bridge-to-transplantation and destination-therapy patient populations; however, infection remains one of the most common causes of mortality during mechanical circulatory support. Thus, serious LVAD infections may negate the benefits of LVAD implantation, resulting in decreased quality of life, increased morbidity and mortality, and increased costs associated with implantation. Prevention of device-related infection is crucial to the cost-effective use of mechanical circulatory support devices. Therefore, adherence to evidence-based infection control and prevention guidelines, meticulous surgical technique and optimal postoperative surgical site care form the foundation for LVAD associated infection prevention.
- Published
- 2005
- Full Text
- View/download PDF
34. Management of adult patients with a left ventricular assist device.
- Author
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Stahovich M, Chillcott S, and Ferber L
- Subjects
- Adult, Aged, California, Cardiomyopathies surgery, Convalescence, Humans, Male, Needs Assessment, Nursing Assessment, Nutrition Assessment, Patient Admission, Patient Discharge, Patient Education as Topic, Postoperative Care nursing, Postoperative Care rehabilitation, Rehabilitation Nursing education, Waiting Lists, Aftercare methods, Heart-Assist Devices, Postoperative Care methods, Rehabilitation Centers organization & administration, Rehabilitation Nursing methods
- Abstract
The number of left ventricular assist device (LVAD) implantations is growing as a result of increased waiting periods for cardiac transplantation and the decreased availability of organ donors. Furthermore, the Food and Drug Administration (FDA) has approved permanent LVAD support. After an acute hospitalization, patients with LVADs may need prolonged convalescence in a healthcare facility because they have complex medical needs and are physically disabled. Admission criteria need to be developed as essential patient and nursing competencies need to be defined as a part of a successful LVAD program in an acute rehabilitation center. Acute rehabilitation centers can help patients with LVADs transition to a home setting.
- Published
- 2004
- Full Text
- View/download PDF
35. Longitudinal change in quality of life and impact on survival after left ventricular assist device implantation.
- Author
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Grady KL, Meyer PM, Dressler D, Mattea A, Chillcott S, Loo A, White-Williams C, Todd B, Ormaza S, Kaan A, Costanzo MR, and Piccione W
- Subjects
- Adult, Aged, Female, Follow-Up Studies, Heart Failure mortality, Heart Failure therapy, Heart Transplantation, Humans, Male, Middle Aged, Patient Satisfaction, Prostheses and Implants, Surveys and Questionnaires, Survival Rate, Heart-Assist Devices, Quality of Life
- Abstract
Background: The HeartMate vented electric left ventricular assist device has been approved for use as destination therapy. Thus, the study of quality-of-life outcomes, as well as morbidity and mortality, is imperative. The purpose of our study was to describe change with time (from 1 month to 1 year) in patients who received a HeartMate vented electric left ventricular assist device as a bridge to heart transplantation and to identify quality-of-life predictors of survival after left ventricular assist device implantation., Methods: A nonrandom sample of 78 patients who received a HeartMate vented electric left ventricular assist device (primarily middle-aged, white married males) who had quality-of-life data at 1, 2, 3, 6, 9, or 12 months after implant was the subject of this report. The sample size decreased with time primarily because of heart transplantation. Patients completed the following booklets of questionnaires: Quality of Life Index, Rating Question Form, Heart Failure Symptom Checklist, and Sickness Impact Profile. Analyses included both descriptive analyses and modeling procedures (mixed-effects models and Cox proportional hazards models)., Results: Quality-of-life outcomes were fairly good and stable from 1 month to 1 year after HeartMate vented electric left ventricular assist device implantation. Both positive and negative changes were detected in all quality-of-life domains (physical and occupational function, social interaction, somatic sensation, and psychological state) after left ventricular assist device insertion. Items from the physical domain of quality of life, specifically walking and dressing oneself, were significantly associated with the risk of dying after left ventricular assist device implantation., Conclusions: Identifying poor quality-of-life outcomes within 1 year after left ventricular assist device implantation provides direction to develop strategies to improve outcomes. Physical and occupational rehabilitation, psychosocial intervention, and monitoring symptom distress and physical disability may contribute to improved quality-of-life outcomes and survival after left ventricular assist device implantation.
- Published
- 2004
- Full Text
- View/download PDF
36. Change in quality of life from after left ventricular assist device implantation to after heart transplantation.
- Author
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Grady KL, Meyer PM, Dressler D, White-Williams C, Kaan A, Mattea A, Ormaza S, Chillcott S, Loo A, Todd B, Costanzo MR, and Piccione W
- Subjects
- Adult, Aged, Australia, Female, Follow-Up Studies, Humans, Male, Middle Aged, Surveys and Questionnaires, United States, Waiting Lists, Heart Transplantation psychology, Heart-Assist Devices psychology, Quality of Life
- Abstract
Background: No studies have analyzed quality of life (QOL) from before to after heart transplantation in patients with a left ventricular assist device (LVAD). Therefore, the purpose of this longitudinal, multi-site study was to compare QOL outcomes of patients listed for heart transplantation who required a left ventricular assist device (LVAD) at 3 months after implantation of an LVAD vs 3 months after heart transplantation., Methods: A non-random sample of 40 patients (predominantly middle-aged, married, white men), who had paired data at both 3 months after LVAD implantation and 3 months after heart transplantation, were investigated. Patients completed self-report questionnaires (with acceptable reliability and validity) at both time periods, including the Quality of Life Index, Rating Question Form, Heart Failure Symptom Checklist, Sickness Impact Profile, LVAD Stressor Scale (completed only after LVAD implant), Heart Transplant Stressor Scale (completed only after heart transplant) and Jalowiec Coping Scale. Descriptive analyses and comparative analyses using paired t-tests were performed with statistical significance set at 0.01., Results: Patients were significantly more satisfied with their lives overall and with their health and functioning at 3 months after heart transplantation as compared with 3 months after LVAD implantation. Mobility, self-care ability, physical ability and overall functional ability improved from 3 months after LVAD implant to 3 months after heart transplant. There was significantly less symptom distress after LVAD implant as compared with after heart transplant for the neurologic, dermatologic and physical sub-scales. Work/school/financial stress was significantly lower after heart transplant vs after LVAD implant. In contrast, 2 other areas of stress were significantly lower after LVAD implant vs after heart transplant: self-care stress and hospital/clinic-related stress., Conclusions: Differences were found in QOL outcomes at 3 months after LVAD implant as compared with 3 months after heart transplant. Our findings point out specific areas of concern with respect to QOL after LVAD implant and post-transplant, some of which are amenable to health-care provider interventions.
- Published
- 2003
- Full Text
- View/download PDF
37. Change in quality of life from before to after discharge following left ventricular assist device implantation.
- Author
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Grady KL, Meyer PM, Mattea A, Dressler D, Ormaza S, White-Williams C, Chillcott S, Kaan A, Loo A, Todd B, Klemme A, Piccione W, and Costanzo MR
- Subjects
- Health Status, Humans, Inpatients psychology, Longitudinal Studies, Male, Middle Aged, Patient Discharge, Prospective Studies, Sickness Impact Profile, Socioeconomic Factors, Stress, Psychological psychology, Attitude to Health, Heart-Assist Devices psychology, Quality of Life
- Abstract
Background: Quality of life (QOL) outcomes after left ventricular assist device (LVAD) implantation from before to after hospital discharge have been examined only in a very small sample of patients. The purposes of this study are to describe change in QOL from before to after hospital discharge in LVAD patients and to determine whether being discharged with an LVAD predicts better QOL than being hospitalized with an LVAD., Methods: A non-random sample of 62 LVAD patients (approximately 50 years old, male, white, married, fairly well-educated) completed self-report questionnaires at >or=2 timepoints post-implant. The questionnaires (Quality of Life Index, Rating Question Form, Heart Failure Symptom Checklist, Sickness Impact Profile, LVAD Stressor Scale, Jalowiec Coping Scale), which were collated into booklets, had acceptable reliability and validity. Longitudinal analyses were performed in 2 steps using 1-sample t-tests and linear mixed effects modeling., Results: Perception of QOL and health status were fairly good both before and after discharge of LVAD patients. Discharge predicted increased satisfaction with socioeconomic areas of life; decreased overall and psychologic stress and stress related to family and friends, self-care and work/school/finances; and decreased physical and self-care disability., Conclusions: QOL outcomes improved from before to after hospital discharge in LVAD patients awaiting heart transplantation. As LVADs potentially become available as destination therapy, in addition to being successful bridges to heart transplantation, QOL outcomes will become more important to study.
- Published
- 2003
- Full Text
- View/download PDF
38. Predictors of quality of life at 1 month after implantation of a left ventricular assist device.
- Author
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Grady KL, Meyer P, Mattea A, Dressler D, Ormaza S, White-Williams C, Chillcott S, Kaan A, Todd B, Loo A, Klemme AL, Piccione W, and Costanzo MR
- Subjects
- Adaptation, Psychological, Adult, Aged, Australia, Female, Heart Failure psychology, Humans, Longitudinal Studies, Male, Middle Aged, Multivariate Analysis, Prospective Studies, Treatment Outcome, United States, Heart Failure surgery, Heart-Assist Devices, Patient Satisfaction statistics & numerical data, Quality of Life, Ventricular Dysfunction, Left surgery
- Abstract
Objectives: To describe quality-of-life outcomes; determine relationships between quality of life and demographic, physical, psychosocial, and clinical variables; and identify predictors of quality of life at 1 month after implantation of a left ventricular assist device., Methods: Patients who received either an implantable pneumatic (n = 38) or a vented electric (n = 54) left ventricular assist device as a bridge to heart transplantation between August 1, 1994, and August 31, 1999, completed 6 instruments used to measure quality of life andfactors related to quality of life. Data were analyzed by using descriptive statistics, Pearson correlations, Mann-Whitney U tests, and forward, stepwise multiple regression., Results: Overall satisfaction with quality of life was quite high as determined from the total score on the Quality of Life Index (mean = 0.69). Patients were very satisfied with the implantation and thought that they would do well after future heart transplant surgery. Patients had a moderate level of stress. Significant predictors of overall quality of life were psychological symptoms, stress, and race; these accounted for 46% of variance in quality of life., Conclusions: Patients were satisfied with their quality of life at 1 month after implantation of a left ventricular assist device. However, they were least satisfied with their health and functioning and yet were optimistic about how well they thought they would do after heart transplantation. Psychological factors were the strongest predictors of satisfaction with overall quality of life.
- Published
- 2002
39. Long-term survival with use of percutaneous extracorporeal life support in patients presenting with acute myocardial infarction and cardiovascular collapse.
- Author
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Jaski BE, Lingle RJ, Overlie P, Favrot LK, Willms DC, Chillcott S, and Dembitsky WP
- Subjects
- Adult, Cardiopulmonary Resuscitation, Female, Humans, Ischemia etiology, Leg blood supply, Male, Middle Aged, Myocardial Revascularization, Oxygen Consumption, Registries, Survival Analysis, Treatment Outcome, Extracorporeal Membrane Oxygenation adverse effects, Myocardial Infarction mortality, Myocardial Infarction therapy, Shock, Cardiogenic mortality, Shock, Cardiogenic therapy
- Abstract
Up to 10% of patients who arrive at the hospital with acute myocardial infarction (AMI) present with or develop cardiogenic shock. Some patients, despite inotropes and intra-aortic balloon pump (IABP) placement, are not hemodynamically stable enough to undergo emergent revascularization. The use of percutaneous extracorporeal life support (ECLS) can stabilize patients to allow effective therapy. In a retrospective review of the first 100 patients emergently placed on ECLS by a nurse-supported physician insertion technique at Sharp Memorial Hospital, 10 patients underwent placement of ECLS after out-of hospital AMI. All AMI patients required intubation for respiratory failure and temporary CPR for cardiovascular collapse before initiation of ECLS. Of the 10 AMI patients placed on ECLS, four (40%) are currently long-term survivors (5.1 +/- 4.2 years; range, 6 months to 11 years). All survivors underwent successful revascularization after placement on ECLS. The cause of death in the other six patients was neurologic insufficiency in two, ineffective ECLS in two, and recurrent cardiovascular collapse after weaning from bypass in two. Total CPR time before initiation of cardiopulmonary bypass was 17 +/- 10.3 minutes for the survivors and 54.2 +/-11.1 minutes for the nonsurvivors (p < 0.001). The average time on ECLS was 29 +/- 26 hours for the survivors and 30 +/-67 hours for the nonsurvivors (p = NS). Leg complications were common among long-term survivors, associated with the use of ECLS (three ischemia, one infection). After AMI and cardiovascular collapse, insertion of ECLS may permit long-term patient survival.
- Published
- 1999
- Full Text
- View/download PDF
40. Left ventricular assist as a viable alternative for cardiac transplantation.
- Author
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Chillcott SR, Atkins PJ, and Adamson RM
- Subjects
- Cardiomyopathies nursing, Ethics, Medical, Humans, Patient Selection, Cardiomyopathies surgery, Heart Transplantation, Heart-Assist Devices
- Abstract
Implantation of left ventricular assist systems (LVASs) is becoming more prevalent for patients with end-stage heart disease who are awaiting cardiac transplantation. The original intent of the LVAS was to provide an alternative to transplantation, but until recently, the LVAS has been approved only as a bridge to transplantation. Now that bridging to transplantation for patients with LVASs has exceeded 2-year periods, permanent implantation is being done as an alternative to transplantation. This article reviews the fundamental components of the HeartMate Vented Electric LVAS (Thermo Cardiosystems, Inc, Woburn, MA) with a focus on patient complications and nursing implications. Additionally, the intraoperative implantation procedure is presented. Finally, ethical and financial considerations related to permanent LVAS implantation are discussed.
- Published
- 1998
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