1. Pediatric, adolescent, and young adult breast and reproductive tumors.
- Author
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Harris CJ, Rowell EE, Jayasinghe Y, Cost C, Childress KJ, Frederick NN, McNally O, Appiah L, and Anazodo A
- Subjects
- Male, Humans, Female, Child, Adolescent, Young Adult, Fertility, Risk Factors, Neoplasms therapy, Testicular Neoplasms complications, Fertility Preservation, Sexual Dysfunction, Physiological etiology, Sexual Dysfunction, Physiological therapy
- Abstract
Tumors of the breast and reproductive organs that occur in children, adolescents, and young adults (AYA) have different biological features and can present special challenges. Although prognosis for these tumors is generally favorable, the long-term effects of treatment can be debilitating. Treatments are often multimodal and may include surgery as well as chemotherapy and/or radiation, which can cause considerable distress and anxiety related to loss of femininity or masculinity, concern over future fertility, or sexual dysfunction. Thus, tumors of the reproductive organs in pediatric/AYA patients require special consideration of the treatment effects beyond the intended oncologic outcome. Multidisciplinary teams should be involved in their care and address issues of fertility, sexual dysfunction, and psychosexual concerns before treatment begins. This review addresses histology, risk factors, prognosis, staging and treatment of gynecologic, breast and testicular cancers in pediatric and AYA patients., (© 2021 Wiley Periodicals LLC.)
- Published
- 2023
- Full Text
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