262 results on '"Chieffo, Daniela Pia Rosaria"'
Search Results
2. Coping with modesty during radiotherapy for breast cancer: a multicentric study
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Boldrini, Luca, Dinapoli, Loredana, Boccia, Edda, Caliandro, Morena, Colangione, Sarah Pia, Elia, Chiara, Pollutri, Veronica, Sartori, Gaia, Gregucci, Fabiana, Marconi, Elisa, Manfrida, Stefania, Masiello, Valeria, Chieffo, Daniela Pia Rosaria, Marazzi, Fabio, Fiorentino, Alba, and Gambacorta, Maria Antonietta
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- 2024
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3. Survey of rehabilitation approaches and plans for individuals with dravet syndrome (RAPIDS) in Italy: Current practices and strategies to progress
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Porto, Chiara, Perulli, Marco, Arpaia, Chiara, Villa, Marianna, Arcangeli, Valentina, Quintiliani, Michela, Gambardella, Maria Luigia, Brando, Carolina, Contaldo, Ilaria, Veredice, Chiara, Zaghi, Vania, Canepa, Giovanna, Borroni, Simona, Chieffo, Daniela Pia Rosaria, and Battaglia, Domenica Immacolata
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- 2024
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4. A systematic review on gender dysphoria in adolescents and young adults: focus on suicidal and self-harming ideation and behaviours
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Marconi, Elisa, Monti, Laura, Marfoli, Angelica, Kotzalidis, Georgios D., Janiri, Delfina, Cianfriglia, Cecilia, Moriconi, Federica, Costa, Stefano, Veredice, Chiara, Sani, Gabriele, and Chieffo, Daniela Pia Rosaria
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- 2023
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5. The Italian version of the Pediatric Quality of Life Inventory™ (PEDSQL™) 3.0 healthcare satisfaction hematology/oncology module: reliability and validity in radiation oncology
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Marconi, Elisa, Beghella Bartoli, Francesco, Meldolesi, Elisa, Mariani, Silvia, Panza, Giulia, Nardangeli, Alessia, Dinapoli, Loredana, Lees, Teresa Carmen, Guido, Antonella, Mastronuzzi, Angela, Ruggiero, Antonio, Gambacorta, Maria Antonietta, Valentini, Vincenzo, Balducci, Mario, Chieffo, Daniela Pia Rosaria, and Chiesa, Silvia
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- 2023
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6. Psychological factors and barriers to donating and receiving milk from human milk banks: A review
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Monti, Laura, Massa, Serena, Mallardi, Maria, Arcangeli, Valentina, Serrao, Francesca, Costa, Simonetta, Vento, Giovanni, Mazza, Marianna, Simonetti, Alessio, Janiri, Delfina, Kotzalidis, Georgios D., Lanzone, Antonio, Mercuri, Eugenio Maria, Sani, Gabriele, and Chieffo, Daniela Pia Rosaria
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- 2024
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7. Predisposition to eating disorders in adults with type 1 diabetes: Comparison between multiple daily injections and continuous subcutaneous insulin infusion
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Policola, Caterina, Di Stasio, Enrico, Rizzi, Alessandro, Focà, Francesca, Tartaglione, Linda, Locantore, Pietro, Ramunno, Vittoria, Leo, Maria Laura, Chieffo, Daniela Pia Rosaria, Rinaldi, Lucio, Della Casa, Silvia, Pontecorvi, Alfredo, and Pitocco, Dario
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- 2023
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8. Exploring the emotional and behavioural profile in paediatric narcolepsy type 1: A case–control study.
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Simoncini Malucelli, Giorgia, Mercante, Anna, Pizza, Fabio, Brunetti, Valerio, Biscarini, Francesco, Vandi, Stefano, Mazzoni, Alice, Franceschini, Christian, Della Marca, Giacomo, Vollono, Catello, Chieffo, Daniela Pia Rosaria, and Plazzi, Giuseppe
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DROWSINESS ,NARCOLEPSY ,MENTAL depression ,PSYCHOLOGICAL factors ,CASE-control method ,BODY mass index ,TOTAL maximum daily load for water pollutants ,YOUTH with attention-deficit hyperactivity disorder - Abstract
Summary: Narcolepsy type 1 (NT1) is a central disorder of hypersomnolence often arising in childhood and adolescence. NT1 has a significant, but poorly defined, psychological impact. We aimed to investigate the psycho‐social functioning of children and adolescents with NT1. We performed a cross‐sectional, child and parent‐reported questionnaire survey in 37 children and adolescents (6–17 years) with NT1, compared with age‐ and sex‐matched controls. Questionnaires (SSHS, ESS‐CHAD, CDI, MASC, CBCL, CRS‐R, and SNAP‐IV) evaluated various aspects of behavioural and emotional profiles, sleep habits, and daytime sleepiness. Subsequently, NT1 intra‐group analysis was performed to investigate the effect of sex (males vs females) and pharmacological treatment (treated vs non‐treated) on psychological features. The NT1 questionnaires total scores were then correlated with the clinical characteristics (age, body mass index [BMI], ESS‐CHAD score, cerebrospinal hypocretin‐1 [Hcrt‐1] levels, and diagnostic delay). Patients with NT1 showed a higher tendency to depressive symptoms, anxiety, somatisation, inattention, hyperactivity, oppositional/defiant problems, and other maladaptive behaviours compared with controls. Among NT1 patients, females showed a higher propensity to anxiety, and non‐treated patients displayed higher depressive symptoms. Psychological symptoms increased with age, BMI, and daytime sleepiness in patients with NT1, while a younger age was associated with more frequent somatisation symptoms. Lower cerebrospinal Hcrt‐1 levels correlated with poorer social competencies, daily activities, and inattention. Diagnostic delay was associated with a higher impact of depressive symptoms and behavioural problems. NT1 in children and adolescents is associated with poorer functioning in multiple psychological domains calling for a multidisciplinary approach and monitoring to reduce disease burden and to prevent psychiatric consequences. [ABSTRACT FROM AUTHOR]
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- 2024
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9. The Role of the Cerebellum in Advanced Cognitive Processes in Children.
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Mastrangelo, Stefano, Peruzzi, Laura, Guido, Antonella, Iuvone, Laura, Attinà, Giorgio, Romano, Alberto, Maurizi, Palma, Chieffo, Daniela Pia Rosaria, and Ruggiero, Antonio
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NEURAL circuitry ,COGNITION disorders ,MOTOR ability ,COGNITIVE development ,LEARNING - Abstract
Over the last several years, a growing body of evidence from anatomical, physiological, and functional neuroimaging studies has increasingly indicated that the cerebellum is actively involved in managing higher order cognitive functions and regulating emotional responses. It has become clear that when children experience congenital or acquired cerebellar lesions, these injuries can lead to a variety of cognitive and emotional disorders, manifesting in different combinations. This underscores the cerebellum's essential role not only throughout developmental stages but particularly in facilitating learning processes, highlighting its critical importance beyond its traditional association with motor control. Furthermore, the intricate neural circuits within the cerebellum are believed to contribute to the fine-tuning of motor actions and coordination but are also increasingly recognized for their involvement in cognitive processes such as attention, language, and problem solving. Recent research has highlighted the importance of cerebellar health and integrity for optimal functioning across various domains of the human experience. [ABSTRACT FROM AUTHOR]
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- 2024
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10. Psychological Experiences of Parents of Pediatric Cancer Patients during and after COVID-19 Pandemic
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Guido, Antonella, primary, Marconi, Elisa, additional, Peruzzi, Laura, additional, Dinapoli, Nicola, additional, Tamburrini, Gianpiero, additional, Attinà, Giorgio, additional, Romano, Alberto, additional, Maurizi, Palma, additional, Mastrangelo, Stefano, additional, Chiesa, Silvia, additional, Gambacorta, Maria Antonietta, additional, Ruggiero, Antonio, additional, and Chieffo, Daniela Pia Rosaria, additional
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- 2024
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11. Long-standing Overt Ventriculomegaly in Adults and Endoscopic Third Ventriculostomy, the Perfect Treatment for the Proper Diagnosis
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Bianchi, Federico, Ducoli, Giorgio, Moriconi, Federica, Chieffo, Daniela Pia Rosaria, Anile, Carmelo, and Tamburrini, Gianpiero
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- 2021
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12. Role of high-density EEG (hdEEG) in pre-surgical epilepsy evaluation in children: case report and review of the literature
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Quintiliani, Michela, Bianchi, Federico, Fuggetta, Filomena, Chieffo, Daniela Pia Rosaria, Ramaglia, Antonia, Battaglia, Domenica Immacolata, and Tamburrini, Gianpiero
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- 2021
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13. Prevalence of burnout and psycho-emotional disorders among non-health workers: a single tertiary care pediatric oncology center experience
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Guido, Antonella, Santoro, Paolo Emilio, DE Cata, Domenica A, Peruzzi, Laura, Chieffo, Daniela Pia Rosaria, Gualano, Maria R, Rossi, Maria Francesca, Moscato, Umberto, Ruggiero, Antonio, Santoro, Paolo E (ORCID:0000-0002-6052-088X), Chieffo, Daniela P, Rossi, Maria F, Moscato, Umberto (ORCID:0000-0002-2568-3966), Ruggiero, Antonio (ORCID:0000-0002-6052-3511), Guido, Antonella, Santoro, Paolo Emilio, DE Cata, Domenica A, Peruzzi, Laura, Chieffo, Daniela Pia Rosaria, Gualano, Maria R, Rossi, Maria Francesca, Moscato, Umberto, Ruggiero, Antonio, Santoro, Paolo E (ORCID:0000-0002-6052-088X), Chieffo, Daniela P, Rossi, Maria F, Moscato, Umberto (ORCID:0000-0002-2568-3966), and Ruggiero, Antonio (ORCID:0000-0002-6052-3511)
- Abstract
BACKGROUND: According to scientific literature, burnout can be described as a multidimensional syndrome with three fundamental dimensions: emotional exhaustion, depersonalization and reduced personal accomplishment. Every day, clown -doctors, play therapists, teachers and volunteers, such as ceramic art therapists, work in pediatric cancer wards to improve the quality of life of hospitalized children and activate positive resources during their therapeutic journey. METHODS: This study investigated burnout levels and the relationship between work -related stress and resilience in a total of 36 operators (clown -doctors, in -hospital teachers, play therapists, and ceramic art therapists), working at the Unit of Pediatric Oncology of IRCCS A. Gemelli University Polyclinic Foundation in Rome, Italy. All participants completed a battery of questionnaires to evaluate burnout (Maslach Burnout Inventory) and resilience (Connor -Davidson Resilience Scale). RESULTS: The results of this study show that these workers are exposed to work -related stress and that the burnout levels are not homogeneous across the various groups considered. The results also show the need to provide non -health hospital workers with a psychological support service or ensure the presence of a mental health professional to help them avoid the risk of burnout. CONCLUSIONS: The heavy emotional burden endured by these operators makes them vulnerable and exposes them to burnout.
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- 2024
14. Psychological Experiences of Parents of Pediatric Cancer Patients during and after COVID-19 Pandemic
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Guido, Antonella, Marconi, Elisa, Peruzzi, Laura, Dinapoli, Nicola, Tamburrini, Gianpiero, Attinà, Giorgio, Romano, Alberto, Maurizi, Palma, Mastrangelo, Stefano, Chiesa, Silvia, Gambacorta, Maria Antonietta, Ruggiero, Antonio, Chieffo, Daniela Pia Rosaria, Marconi, Elisa (ORCID:0000-0001-6722-8390), Tamburrini, Gianpiero (ORCID:0000-0002-7139-5711), Maurizi, Palma (ORCID:0000-0002-5930-0193), Mastrangelo, Stefano (ORCID:0000-0002-3305-6014), Chiesa, Silvia (ORCID:0000-0003-0168-3459), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), Ruggiero, Antonio (ORCID:0000-0002-6052-3511), Guido, Antonella, Marconi, Elisa, Peruzzi, Laura, Dinapoli, Nicola, Tamburrini, Gianpiero, Attinà, Giorgio, Romano, Alberto, Maurizi, Palma, Mastrangelo, Stefano, Chiesa, Silvia, Gambacorta, Maria Antonietta, Ruggiero, Antonio, Chieffo, Daniela Pia Rosaria, Marconi, Elisa (ORCID:0000-0001-6722-8390), Tamburrini, Gianpiero (ORCID:0000-0002-7139-5711), Maurizi, Palma (ORCID:0000-0002-5930-0193), Mastrangelo, Stefano (ORCID:0000-0002-3305-6014), Chiesa, Silvia (ORCID:0000-0003-0168-3459), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), and Ruggiero, Antonio (ORCID:0000-0002-6052-3511)
- Abstract
This study aimed to evaluate how the COVID-19 pandemic affected the psychological well-being of parents of pediatric oncology patients two years after the pandemic started. The authors' objective was to make a detailed comparison between the data collected in the current study and the data gathered in the previous research with the aim of observing any changes, whether for better or worse, at the psychological level in the caregivers of the patients in question. This research could be of great use for monitoring the psychological health of the sample and for being able to intervene promptly in the event of the worsening of the reported symptoms. Background: Family members dealing with the devastating impact of a cancer diagnosis are now facing even greater vulnerability due to the COVID-19 pandemic. Alongside the already overwhelming trauma, they must also bear the distressing burden of the infection risks. The purpose of this study was to examine and explore the effects in parents of pediatric cancer patients two years after the start of the COVID-19 pandemic to compare these data with the previous data. Methods: We conducted a single-center prospective observational study, enrolling 75 parents of 42 pediatric oncology patients. Four questionnaires (IES-R; PSS; STAI-Y and PedsQL) were given to the parents 2 years after the first evaluation. Results: The bivariate matrix of correlation found a strong significant positive correlation between IES-R and PSS scores (r = 0.526, p < 0.001) as in T1. Stress symptoms (t = 0.00, p < 0.001) and levels of anxiety (trait) (t = 0.32, p < 0.001) remained unchanged; anxiety state levels appeared to have increased (t = 0.425, p < 0.001); there was a significant decrease in the PedsQL tot (t = 5.25, p < 0.001). Conclusions: The COVID-19 pandemic has influenced the levels of stress and anxiety of parents and the quality of life of patients, also correlating with the traumatic impact of the diagnosis.
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- 2024
15. The Relationship between Language and Technology: How Screen Time Affects Language Development in Early Life—A Systematic Review
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Massaroni, Valentina, primary, Delle Donne, Valentina, additional, Marra, Camillo, additional, Arcangeli, Valentina, additional, and Chieffo, Daniela Pia Rosaria, additional
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- 2023
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16. Outpatient care for adolescents’ and young adults’ mental health: promoting self- and others’ understanding through a metacognitive interpersonal therapy-informed psychological intervention
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Marconi, Elisa, primary, Monti, Laura, additional, Fredda, Giulia, additional, Kotzalidis, Georgios D., additional, Janiri, Delfina, additional, Zani, Valentina, additional, Vitaletti, Debora, additional, Simone, Maria Velia, additional, Piciollo, Simone, additional, Moriconi, Federica, additional, Di Pietro, Emanuela, additional, Popolo, Raffaele, additional, Dimaggio, Giancarlo, additional, Veredice, Chiara, additional, Sani, Gabriele, additional, and Chieffo, Daniela Pia Rosaria, additional
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- 2023
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17. Use of Lithium in Pediatric Bipolar Disorders and Externalizing Childhood- related Disorders: A Systematic Review of Randomized Controlled Trials
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Janiri, Delfina, Moccia, Lorenzo, Montanari, Silvia, Zani, Valentina, Prinari, Claudia, Monti, Laura, Chieffo, Daniela Pia Rosaria, Mazza, Marianna, Simonetti, Alessio, Kotzalidis, Georgios D, and Janiri, Luigi
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Externalizing disorder ,Pediatric ,Pharmacology ,Bipolar disorder ,Settore M-PSI/02 - PSICOBIOLOGIA E PSICOLOGIA FISIOLOGICA ,Settore M-PSI/08 - PSICOLOGIA CLINICA ,General Medicine ,Lithium ,Conduct disorder ,Psychiatry and Mental health ,Settore MED/39 - NEUROPSICHIATRIA INFANTILE ,Neurology ,Settore M-PSI/01 - PSICOLOGIA GENERALE ,Pharmacology (medical) ,Neurology (clinical) ,Children - Abstract
Background: Lithium is the standard treatment for bipolar disorders (BD) in adults. There is a dearth of data on its use in the pediatric age. This review aimed to investigate the use of lithium in pediatric bipolar disorder (BD) and other externalizing childhood-related disorders. Methods: We applied the Preferred Reporting Items for Systematic Reviews and Meta-analyses criteria (PRISMA) to identify randomized controlled trials evaluating the use of lithium in pediatric (BD), conduct disorder (CD), attention deficit hyperactivity disorder, oppositional defiant disorder, and disruptive mood dysregulation disorder. The primary outcome of our study was to evaluate the efficacy of lithium compared to a placebo or other pharmacological agents. The secondary outcomes were acceptability and tolerability. Results: Twelve studies were eligible, 8 on BD and 4 on CD. Overall, 857 patients were treated with lithium. No studies for externalizing disorder diagnoses were identified. Regarding BD patients (n = 673), efficacy results suggested that lithium was superior to placebo in manic/mixed episodes but inferior to antipsychotics. Lithium efficacy ranged from 32% to 82.4%. Results on maintenance need to be expanded. Comorbidity rates with other externalizing disorders were extremely high, up to 98.6%. Results in CD patients (n= 184) suggested the efficacy of lithium, especially for aggressive behaviors. No severe adverse events directly related to lithium were reported in BD and CD; common side effects were similar to adults. Conclusions: This systematic review supports the use of lithium in BD and CD as an efficacious and generally well‐tolerated treatment in the pediatric age. However, evidence is limited due to the paucity of available data.
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- 2023
18. Exploring the emotional and behavioural profile in paediatric narcolepsy type 1: A case–control study
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Simoncini Malucelli, Giorgia, primary, Mercante, Anna, additional, Pizza, Fabio, additional, Brunetti, Valerio, additional, Biscarini, Francesco, additional, Vandi, Stefano, additional, Mazzoni, Alice, additional, Franceschini, Christian, additional, Della Marca, Giacomo, additional, Vollono, Catello, additional, Chieffo, Daniela Pia Rosaria, additional, and Plazzi, Giuseppe, additional
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- 2023
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19. Specific Learning Disorders (SLD) and Behavior Impairment: Comorbidity or Specific Profile?
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Chieffo, Daniela Pia Rosaria, primary, Arcangeli, Valentina, additional, Moriconi, Federica, additional, Marfoli, Angelica, additional, Lino, Federica, additional, Vannuccini, Sofia, additional, Marconi, Elisa, additional, Turrini, Ida, additional, Brogna, Claudia, additional, Veredice, Chiara, additional, Antonietti, Alessandro, additional, Sani, Gabriele, additional, and Mercuri, Eugenio Maria, additional
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- 2023
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20. Are the Post-COVID-19 Posttraumatic Stress Disorder (PTSD) Symptoms Justified by the Effects of COVID-19 on Brain Structure? A Systematic Review
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Kotzalidis, Georgios D., primary, Ferrara, Ottavia Marianna, additional, Margoni, Stella, additional, Ieritano, Valentina, additional, Restaino, Antonio, additional, Bernardi, Evelina, additional, Fischetti, Alessia, additional, Catinari, Antonello, additional, Monti, Laura, additional, Chieffo, Daniela Pia Rosaria, additional, Simonetti, Alessio, additional, and Sani, Gabriele, additional
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- 2023
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21. Case report: Post-COVID new-onset neurocognitive decline with bilateral mesial-temporal hypometabolism in two previously healthy sisters
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Cocciolillo, Fabrizio, primary, Chieffo, Daniela Pia Rosaria, additional, Giordano, Alessandro, additional, Arcangeli, Valentina, additional, Lazzareschi, Ilaria, additional, Morello, Rosa, additional, Zampino, Giuseppe, additional, Valentini, Piero, additional, and Buonsenso, Danilo, additional
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- 2023
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22. The Relationship between Language and Technology: How Screen Time Affects Language Development in Early Life—A Systematic Review.
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Massaroni, Valentina, Delle Donne, Valentina, Marra, Camillo, Arcangeli, Valentina, and Chieffo, Daniela Pia Rosaria
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SCREEN time ,CHILDREN'S language ,COGNITIVE development ,LANGUAGE acquisition ,DIGITAL media - Abstract
Screen time refers to the amount of time a child is exposed to a screen, that is, television, computer, smartphone, or any other digital medium. Prolonged screen time in the first years of life may affect a child's cognitive abilities, especially language acquisition. A systematic review was conducted, following the PRISMA-P guidelines, with the aim to explore the available literature relating to the impact of screen time on children's language development. This review identified 18 articles. The articles reviewed showed that prolonged screen time and exposure to screens in the first 2 years of life can negatively affect language development and communication skills, in terms of comprehension and vocabulary range. In addition, overexposure to screens in the early years can affect overall cognitive development, especially attention to environmental stimuli, social experiences, problem solving, and communication with others, e.g., the alternance of rhythms and roles in a conversation. In conclusion, our systematic review supports the idea that preschool screen time has negative effects on children's cognitive and language development. Television seems to be the medium most detrimental to children's skills, as it is used in a passive manner and is often characterised by language and content that do not suit the child's processing mode. Future studies should increasingly focus on the digital media that children possess at an early age, such as mobile phones and tablets, and on how children relate to the online world, such as social networks. [ABSTRACT FROM AUTHOR]
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- 2024
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23. COVID-19 pandemic in the intensive care unit: Psychological implications and interventions, a systematic review
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Monti, Laura, primary, Marconi, Elisa, additional, Bocci, Maria Grazia, additional, Kotzalidis, Georgios Demetrios, additional, Mazza, Marianna, additional, Galliani, Carolina, additional, Tranquilli, Sara, additional, Vento, Giovanni, additional, Conti, Giorgio, additional, Sani, Gabriele, additional, Antonelli, Massimo, additional, and Chieffo, Daniela Pia Rosaria, additional
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- 2023
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24. The Nrf2 Pathway in Depressive Disorders: A Systematic Review of Animal and Human Studies
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Sani, Gabriele, primary, Margoni, Stella, additional, Brugnami, Andrea, additional, Ferrara, Ottavia Marianna, additional, Bernardi, Evelina, additional, Simonetti, Alessio, additional, Monti, Laura, additional, Mazza, Marianna, additional, Janiri, Delfina, additional, Moccia, Lorenzo, additional, Kotzalidis, Georgios D., additional, Chieffo, Daniela Pia Rosaria, additional, and Janiri, Luigi, additional
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- 2023
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25. Brain Tumor at Diagnosis: From Cognition and Behavior to Quality of Life
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Chieffo, Daniela Pia Rosaria, primary, Lino, Federica, additional, Ferrarese, Daniele, additional, Belella, Daniela, additional, Della Pepa, Giuseppe Maria, additional, and Doglietto, Francesco, additional
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- 2023
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26. Specific Learning Disorders (SLD) and behavior impairment: Comorbidity or specific profile?
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Chieffo, Daniela Pia Rosaria, Arcangeli, Valentina, Moriconi, F., Marfoli, A., Lino, F., Vannuccini, S., Marconi, Elisa, Turrini, Ida, Brogna, Claudia, Veredice, Chiara, Antonietti, Alessandro, Sani, Gabriele, Mercuri, Eugenio Maria, Chieffo D. P. R., Arcangeli V., Marconi E., Turrini I., Brogna C., Veredice C., Antonietti A. (ORCID:0000-0002-7212-8076), Sani G. (ORCID:0000-0002-9767-8752), Mercuri E. M. (ORCID:0000-0002-9851-5365), Chieffo, Daniela Pia Rosaria, Arcangeli, Valentina, Moriconi, F., Marfoli, A., Lino, F., Vannuccini, S., Marconi, Elisa, Turrini, Ida, Brogna, Claudia, Veredice, Chiara, Antonietti, Alessandro, Sani, Gabriele, Mercuri, Eugenio Maria, Chieffo D. P. R., Arcangeli V., Marconi E., Turrini I., Brogna C., Veredice C., Antonietti A. (ORCID:0000-0002-7212-8076), Sani G. (ORCID:0000-0002-9767-8752), and Mercuri E. M. (ORCID:0000-0002-9851-5365)
- Abstract
Specific Learning Disorder (SLD) is a neurodevelopmental disorder characterized by difficulties in perceiving and processing verbal and non-verbal information. It is usually accompanied by impaired academic skills leading to school dropout and emotional disturbances, resulting in significant distress and behavioral problems. Methods: A cognitive, academic, and emotional-behavioral assessment was performed at T0 and T1 in children and adolescents with SLD. Participants received psychotherapy and speech therapy treatment from T0 to T1. Results: In SLD,the most compromised cognitive functions were working memory and writing skills. An impact on academic abilities was found. Children and adolescents with SLD experience greater anxiety and depression levels compared to their control peers. Conclusions: SLD may adversely influence psychological well-being. To counteract such a consequence, more specific cognitive and academic skill-oriented strategies should be taken into consideration.
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- 2023
27. Association between Older Age and Psychiatric Symptoms in a Population of Hospitalized Patients with COVID-19
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Cipriani, Maria Camilla, Pais, Cristina, Savoia, Vezio, Falsiroli, Cinzia, Bellieni, Andrea, Cingolani, Antonella, Fantoni, Massimo, Chieffo, Daniela Pia Rosaria, Sani, Gabriele, Landi, Francesco, Landi, Giovanni, Liperoti, Rosa, Cingolani, Antonella (ORCID:0000-0002-3793-2755), Fantoni, Massimo (ORCID:0000-0001-6913-8460), Sani, Gabriele (ORCID:0000-0002-9767-8752), Landi, Francesco (ORCID:0000-0002-3472-1389), Liperoti, Rosa (ORCID:0000-0003-3740-1687), Cipriani, Maria Camilla, Pais, Cristina, Savoia, Vezio, Falsiroli, Cinzia, Bellieni, Andrea, Cingolani, Antonella, Fantoni, Massimo, Chieffo, Daniela Pia Rosaria, Sani, Gabriele, Landi, Francesco, Landi, Giovanni, Liperoti, Rosa, Cingolani, Antonella (ORCID:0000-0002-3793-2755), Fantoni, Massimo (ORCID:0000-0001-6913-8460), Sani, Gabriele (ORCID:0000-0002-9767-8752), Landi, Francesco (ORCID:0000-0002-3472-1389), and Liperoti, Rosa (ORCID:0000-0003-3740-1687)
- Abstract
Increased rates of anxiety and depression have been reported for older adults during the COVID-19 pandemic. However, little is known regarding the onset of mental health morbidity during the acute phase of the disease and the role of age as potential independent risk factor for psychiatric symptoms. The cross-sectional association between older age and psychiatric symptoms has been estimated in a sample of 130 patients hospitalized for COVID-19 during the first and second wave of the pandemic. Compared to younger patients, those who were 70 years of age or older resulted at a higher risk of psychiatric symptoms measured on the Brief Psychiatric Symptoms Rating Scale (BPRS) (adjusted (adj.) odds ratio (OR) 2.36, 95% confidence interval (CI) 1.05-5.30) and delirium (adj. OR 5.24, 95% CI 1.63-16.8)). No association was found between older age and depressive symptoms or anxiety. Age was associated with psychiatric symptoms independently of gender, marital status, history of psychiatric illness, severity of disease and cardiovascular morbidity. Older adults appear at high risk of developing psychiatric symptoms related to COVID-19 disease during hospital stay. Multidisciplinary preventive and therapeutic interventions should be implemented to reduce the risk of psychiatric morbidity and related adverse health care outcomes among older hospital inpatients with COVID-19.
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- 2023
28. Brain Tumor at Diagnosis: From Cognition and Behavior to Quality of Life
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Chieffo, Daniela Pia Rosaria, Lino, F., Ferrarese, Daniele, Belella, D., Della Pepa, Giuseppe Maria, Doglietto, Francesco, Chieffo D. P. R., Ferrarese D., Della Pepa G. M. (ORCID:0000-0001-8698-3359), Doglietto F. (ORCID:0000-0002-7438-0734), Chieffo, Daniela Pia Rosaria, Lino, F., Ferrarese, Daniele, Belella, D., Della Pepa, Giuseppe Maria, Doglietto, Francesco, Chieffo D. P. R., Ferrarese D., Della Pepa G. M. (ORCID:0000-0001-8698-3359), and Doglietto F. (ORCID:0000-0002-7438-0734)
- Abstract
Background: The present narrative review aims to discuss cognitive–emotional–behavioral symptoms in adults with brain tumors at the time of diagnosis. Methods: The PubMed database was searched considering glioma, pituitary adenoma, and meningioma in adulthood as pathologies, together with cognitive, neuropsychological, or behavioral aspects. Results: Although a significant number of studies describe cognitive impairment after surgery or treatment in adults with brain tumors, only few focus on cognitive–emotional–behavioral symptoms at diagnosis. Furthermore, the importance of an effective communication and its impact on patients’ quality of life and compliance with treatment are seldom discussed. Conclusions: Adults with brain tumors have needs in terms of cognitive–emotional–behavioral features that are detectable at the time of diagnosis; more research is needed to identify effective communication protocols in order to allow a higher perceived quality of life in these patients.
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- 2023
29. Eye Movement Desensitization and Reprocessing (EMDR) as a Possible Evidence-Based Rehabilitation Treatment Option for a Patient with ADHD and History of Adverse Childhood Experiences: A Case Report Study
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Guidetti, Clotilde, Brogna, Patrizia, Chieffo, Daniela Pia Rosaria, Turrini, Ida, Arcangeli, Valentina, Rausa, Azzurra, Bianchetti, Maddalena, Rolleri, Elisa, Santomassimo, Chiara, Di Cesare, Gianluigi, Ducci, Giuseppe, Romeo, Domenico Marco, Brogna, Claudia, Romeo, Domenico M (ORCID:0000-0002-6229-1208), Guidetti, Clotilde, Brogna, Patrizia, Chieffo, Daniela Pia Rosaria, Turrini, Ida, Arcangeli, Valentina, Rausa, Azzurra, Bianchetti, Maddalena, Rolleri, Elisa, Santomassimo, Chiara, Di Cesare, Gianluigi, Ducci, Giuseppe, Romeo, Domenico Marco, Brogna, Claudia, and Romeo, Domenico M (ORCID:0000-0002-6229-1208)
- Abstract
Background: Children with Attention Deficit Hyperactivity Disorder (ADHD) having a history of adverse childhood experiences (ACEs) could be very difficult to treat with standard psychotherapeutic approaches. Some children diagnosed with ADHD may have Post-Traumatic Stress Disorder (PTSD) or have had experienced a significant traumatic event. Trauma and PTSD could exacerbate ADHD core symptoms and be a risk factor of poor outcome response. Objective: to report for the first time the history of a patient with ADHD and ACE successfully treated with an EMDR approach. Conclusion: EMDR could be a promising treatment for ADHD children with a history of traumatic experiences in addition to pharmacological treatments.
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- 2023
30. Integration of art and technology in personalized radiation oncology care: Experiences, evidence, and perspectives
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Casà, Calogero, Dinapoli, Loredana, Marconi, Elisa, Chiesa, Silvia, Cornacchione, Patrizia, Beghella Bartoli, Francesco, Bracci, Serena, Salvati, Alessandra, Scalise, Sara, Colloca, Giuseppe Ferdinando, Chieffo, Daniela Pia Rosaria, Gambacorta, Maria Antonietta, Valentini, Vincenzo, Tagliaferri, Luca, Marconi, Elisa (ORCID:0000-0001-6722-8390), Chiesa, Silvia (ORCID:0000-0003-0168-3459), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), Valentini, Vincenzo (ORCID:0000-0003-4637-6487), Tagliaferri, Luca (ORCID:0000-0003-2308-0982), Casà, Calogero, Dinapoli, Loredana, Marconi, Elisa, Chiesa, Silvia, Cornacchione, Patrizia, Beghella Bartoli, Francesco, Bracci, Serena, Salvati, Alessandra, Scalise, Sara, Colloca, Giuseppe Ferdinando, Chieffo, Daniela Pia Rosaria, Gambacorta, Maria Antonietta, Valentini, Vincenzo, Tagliaferri, Luca, Marconi, Elisa (ORCID:0000-0001-6722-8390), Chiesa, Silvia (ORCID:0000-0003-0168-3459), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), Valentini, Vincenzo (ORCID:0000-0003-4637-6487), and Tagliaferri, Luca (ORCID:0000-0003-2308-0982)
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Cancer diagnoses expose patients to traumatic stress, sudden changes in daily life, changes in the body and autonomy, with even long-term consequences, and in some cases, to come to terms with the end-of-life. Furthermore, rising survival rates underline that the need for interventions for emotional wellbeing is in growing demand by patients and survivors. Cancer patients frequently have compliance problems, difficulties during treatment, stress, or challenges in implementing healthy behaviors. This scenario was highlighted during the COVID-19 emergency. These issues often do not reach the clinical attention of dedicated professionals and could also become a source of stress or burnout for professionals. So, these consequences are evident on individual, interpersonal, and health system levels. Oncology services have increasingly sought to provide value-based health care, considering resources invested, with implications for service delivery and related financing mechanisms. Value-based health care can improve patient outcomes, often revealed by patient outcome measures while seeking balance with economical budgets. The paper aims to show the Gemelli Advanced Radiation Therapy (ART) experience of personalizing the patients' care pathway through interventions based on technologies and art, the personalized approach to cancer patients and their role as "co-stars" in treatment care. The paper describes the vision, experiences, and evidence that have guided clinical choices involving patients and professionals in a co-constructed therapeutic pathway. We will explore this approach by describing: the various initiatives already implemented and prospects, with particular attention to the economic sustainability of the paths proposed to patients; the several pathways of personalized care, both from the patient's and healthcare professional perspective, that put the person's experience at the Gemelli ART Center. The patient's satisfaction with the treatment and economic outco
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- 2023
31. A Longitudinal Follow-Up Study of Intellectual Function in Duchenne Muscular Dystrophy over Age: Is It Really Stable?
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Chieffo, Daniela Pia Rosaria, Moriconi, Federica, Pane, Marika, Lucibello, Simona, Ferraroli, Elisabetta, Norcia, Giulia, Ricci, Martina, Capasso, Anna, Cicala, Gianpaolo, Buchignani, Bianca, Coratti, Giorgia, Cutrona, Costanza, Pelizzari, Monia, Brogna, Claudia, Hendriksen, Jos G M, Muntoni, Francesco, Mercuri, Eugenio Maria, Chieffo, Daniela P R, Pane, Marika (ORCID:0000-0002-4851-6124), Coratti, Giorgia (ORCID:0000-0001-6666-5628), Mercuri, Eugenio (ORCID:0000-0002-9851-5365), Chieffo, Daniela Pia Rosaria, Moriconi, Federica, Pane, Marika, Lucibello, Simona, Ferraroli, Elisabetta, Norcia, Giulia, Ricci, Martina, Capasso, Anna, Cicala, Gianpaolo, Buchignani, Bianca, Coratti, Giorgia, Cutrona, Costanza, Pelizzari, Monia, Brogna, Claudia, Hendriksen, Jos G M, Muntoni, Francesco, Mercuri, Eugenio Maria, Chieffo, Daniela P R, Pane, Marika (ORCID:0000-0002-4851-6124), Coratti, Giorgia (ORCID:0000-0001-6666-5628), and Mercuri, Eugenio (ORCID:0000-0002-9851-5365)
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The aim of the study was to retrospectively evaluate the consistency of longitudinal findings on intellectual functioning in DMD boys and their relationship to behavioral and neuropsychiatric difficulties. The cohort included 70 patients of age 3 to 17 years with at least two assessments using the Wechsler scales. CBCL and clinical observation of behavior were also performed. Changes in total intelligence quotient were interpreted as stable or not stable using the reliable-change method. On the first assessment 43/70 had normal quotients, 18 borderline, 5 mild, and 4 moderate intellectual disability, while 27/70 had no behavioral disorders, 17 had abnormal CBCL, and 26 patients had clear signs of attention deficits despite normal CBCL. The remaining seven were untestable. The mean total intelligence quotient change in the cohort was -2.99 points (SD: 12.29). Stable results on TIQ were found in 63% of the paired assessments. A third of the consecutive cognitive assessments showed a difference of more than 11 points with changes up to 42 points. Boys with no behavioral/attention disorder had smaller changes than those with attention (p = 0.007) and behavioral disorders (p = 0.002). Changes in IQ may occur in Duchenne and are likely to be associated with behavioral or attention deficits.
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- 2023
32. Depressive Symptoms during Pregnancy: Prevalence and Correlates with Affective Temperaments and Psychosocial Factors
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Mazza, Marianna, Avallone, Carla, Kotzalidis, G. D., Marano, G., Moccia, Lorenzo, Serio, Anna Maria, Balocchi, M., Sessa, I., Janiri, Delfina, De Luca, Ilaria, Brisi, Caterina, Spera, Maria Chiara, Monti, Laura, Gonsalez del Castillo, A., Angeletti, G., Chieffo, Daniela Pia Rosaria, Rinaldi, Lucio, Janiri, Luigi, Lanzone, Antonio, Scambia, Giovanni, Mercuri, Eugenio Maria, Sani, Gabriele, Mazza M., Avallone C., Moccia L., Serio A. M., Janiri D., De Luca I., Brisi C., Spera M. C., Monti L., Chieffo D., Rinaldi L. (ORCID:0000-0002-1480-9324), Janiri L. (ORCID:0000-0002-1633-9418), Lanzone A. (ORCID:0000-0003-4119-414X), Scambia G. (ORCID:0000-0003-2758-1063), Mercuri E. M. (ORCID:0000-0002-9851-5365), Sani G. (ORCID:0000-0002-9767-8752), Mazza, Marianna, Avallone, Carla, Kotzalidis, G. D., Marano, G., Moccia, Lorenzo, Serio, Anna Maria, Balocchi, M., Sessa, I., Janiri, Delfina, De Luca, Ilaria, Brisi, Caterina, Spera, Maria Chiara, Monti, Laura, Gonsalez del Castillo, A., Angeletti, G., Chieffo, Daniela Pia Rosaria, Rinaldi, Lucio, Janiri, Luigi, Lanzone, Antonio, Scambia, Giovanni, Mercuri, Eugenio Maria, Sani, Gabriele, Mazza M., Avallone C., Moccia L., Serio A. M., Janiri D., De Luca I., Brisi C., Spera M. C., Monti L., Chieffo D., Rinaldi L. (ORCID:0000-0002-1480-9324), Janiri L. (ORCID:0000-0002-1633-9418), Lanzone A. (ORCID:0000-0003-4119-414X), Scambia G. (ORCID:0000-0003-2758-1063), Mercuri E. M. (ORCID:0000-0002-9851-5365), and Sani G. (ORCID:0000-0002-9767-8752)
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Pregnancy is a unique experience in women’s life, requiring a great ability of adaptation and self-reorganization; vulnerable women may be at increased risk of developing depressive symptoms. This study aimed to examine the incidence of depressive symptomatology during pregnancy and to evaluate the role of affective temperament traits and psychosocial risk factors in predicting them. We recruited 193 pregnant women, collected data regarding sociodemographic, family and personal clinical variables, social support and stressful life events and administered the Mood Disorder Questionnaire (MDQ), the Patient Health Questionnaire-9 (PHQ-9), and the Temperament Evaluation of Memphis, Pisa, Paris and San Diego-Autoquestionnaire (TEMPS-A). In our sample, prevalence of depressive symptomatology was 41.45% and prevalence of depression was 9.85% (6.75% mild and 3.10% moderate depression). We have chosen a cutoff >4 on PHQ-9 to identify mild depressive symptoms which may predict subsequent depression. Statistically significant differences between the two groups were found in the following factors: gestational age, occupation, partner, medical conditions, psychiatric disorders, family psychiatric history, stressful life events, and TEMPS-A mean scores. In our sample mean scores on all affective temperaments but the hyperthymic, were significantly lower in the control group. Only depressive and hyperthymic temperaments were found to be, respectively, risk and protective factors for depressive symptomatology. The current study confirms the high prevalence and complex aetiology of depressive symptomatology during pregnancy and suggests that affective temperament assessment seems to be a useful adjunctive instrument to predict depressive symptomatology during pregnancy and postpartum.
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- 2023
33. COVID-19 pandemic in the intensive care unit: Psychological implications and interventions, a systematic review
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Monti, Laura, Marconi, Elisa, Bocci, Maria Grazia, Kotzalidis, Georgios Demetrio, Mazza, Marianna, Galliani, Carolina, Tranquilli, Sara, Vento, Giovanni, Conti, Giorgio, Sani, Gabriele, Antonelli, Massimo, Chieffo, Daniela Pia Rosaria, Marconi, Elisa (ORCID:0000-0001-6722-8390), Vento, Giovanni (ORCID:0000-0002-8132-5127), Conti, Giorgio (ORCID:0000-0002-8566-9365), Sani, Gabriele (ORCID:0000-0002-9767-8752), Antonelli, Massimo (ORCID:0000-0003-3007-1670), Monti, Laura, Marconi, Elisa, Bocci, Maria Grazia, Kotzalidis, Georgios Demetrio, Mazza, Marianna, Galliani, Carolina, Tranquilli, Sara, Vento, Giovanni, Conti, Giorgio, Sani, Gabriele, Antonelli, Massimo, Chieffo, Daniela Pia Rosaria, Marconi, Elisa (ORCID:0000-0001-6722-8390), Vento, Giovanni (ORCID:0000-0002-8132-5127), Conti, Giorgio (ORCID:0000-0002-8566-9365), Sani, Gabriele (ORCID:0000-0002-9767-8752), and Antonelli, Massimo (ORCID:0000-0003-3007-1670)
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BACKGROUND The coronavirus disease 2019 (COVID-19) pandemic produced changes in intensive care units (ICUs) in patient care and health organizations. The pandemic event increased patients' risk of developing psychological symptoms during and after hospitalisation. These consequences also affected those family members who could not access the hospital. In addition, the initial lack of knowledge about the virus and its management, the climate of fear and uncertainty, the increased workload and the risk of becoming infected and being contagious, had a strong impact on healthcare staff and organizations. This highlighted the importance of interventions aimed at providing psychological support to ICUs, involving patients, their relatives, and the staff; this might involve the reorganisation of the daily routine and rearrangement of ICU staff duties.AIM To conduct a systematic review of psychological issues in ICUs during the COVID-19 pandemic involving patients, their relatives, and ICU staff.METHODS We investigated the PubMed and the ClinicalTrials.gov databases and found 65 eligible articles, upon which we commented.RESULTS Our results point to increased perceived stress and psychological distress in staff, patients and their relatives and increased worry for being infected with severe acute respiratory syndrome coronavirus-2 in patients and relatives. Furthermore, promising results were obtained for some psychological programmes aiming at improving psychological measures in all ICU categories.CONCLUSION As the pandemic limited direct inter-individual interactions, the role of interventions using digital tools and virtual reality is becoming increasingly important. All considered, our results indicate an essential role for psychologists in ICUs.
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- 2023
34. Cognitive function in DMD carriers: personal case series and literature review
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Carraro, L., Iosca, A., Dainesi, M. I., Fusco, Salvatore, Chieffo, Daniela Pia Rosaria, Moriconi, Federica, D'Amario, Giulia, Pane, Marika, Mercuri, Eugenio Maria, Berardinelli, A., Fusco S. (ORCID:0000-0003-3294-0016), Chieffo D. P. R., Moriconi F., d'Amario G., Pane M. (ORCID:0000-0002-4851-6124), Mercuri E. (ORCID:0000-0002-9851-5365), Carraro, L., Iosca, A., Dainesi, M. I., Fusco, Salvatore, Chieffo, Daniela Pia Rosaria, Moriconi, Federica, D'Amario, Giulia, Pane, Marika, Mercuri, Eugenio Maria, Berardinelli, A., Fusco S. (ORCID:0000-0003-3294-0016), Chieffo D. P. R., Moriconi F., d'Amario G., Pane M. (ORCID:0000-0002-4851-6124), and Mercuri E. (ORCID:0000-0002-9851-5365)
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Improvement in clinical conditions allowed physicians to pay more attention to the cognitive function in DMD patients, leading to description of a cognitive impairment not only in affected males, but in female carriers as well. This study aimed to investigate the cognitive involvement in a cohort of DMD carriers and to summarize the current knowledge about the intellectual involvement and neuropsychological profile in DMD/BMD carriers. Our case series consisted of 22 carrier patients from two different centers (IRCCS Mondino, Pavia and Policlinico Gemelli, Rome), for whom we retrospectively collected cognitive, clinical and genetic data. For literature review, we selected 9 studies published in English language from 2011 to 2023 and cited in PubMed. We found that the average IQ of DMD carriers was lower (74; very low) than the average score on normal curve (100 as average standard score). Furthermore, about 50% of them fell in the “extremely low IQ” range, compared with 2-3% of general population. A higher incidence of intellectual disability was confirmed in symptomatic DMD carriers (mean IQ 66; extremely low) from IRCCS Mondino, but not in the asymptomatic ones (mean IQ 99; average), when compared to the general population. Current literature, albeit limited, seems to confirm the presence of a cognitive impairment in carriers, although milder than in affected males but with a similar neuropsychological profile. However, further studies are necessary to delve deeper into this issue and provide adequate educational support.
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- 2023
35. Primary emotional systems, childhood trauma, and suicidal ideation in youths with bipolar disorders
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Janiri, Delfina, Moccia, Lorenzo, Montanari, Silvia, Simonetti, Alessio, Conte, Eliana, Chieffo, Daniela Pia Rosaria, Monti, Laura, Kotzalidis, G. D., Janiri, Luigi, Sani, Gabriele, Janiri D., Moccia L., Montanari S., Simonetti A., Conte E., Chieffo D., Monti L., Janiri L. (ORCID:0000-0002-1633-9418), Sani G. (ORCID:0000-0002-9767-8752), Janiri, Delfina, Moccia, Lorenzo, Montanari, Silvia, Simonetti, Alessio, Conte, Eliana, Chieffo, Daniela Pia Rosaria, Monti, Laura, Kotzalidis, G. D., Janiri, Luigi, Sani, Gabriele, Janiri D., Moccia L., Montanari S., Simonetti A., Conte E., Chieffo D., Monti L., Janiri L. (ORCID:0000-0002-1633-9418), and Sani G. (ORCID:0000-0002-9767-8752)
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Childhood trauma is a prominent environmental stressor associated with both BD diagnosis and suicide. Primary emotional systems are altered in adult BD and may contribute to suicide risk in youths. Objective: The aim of this study was to investigate primary emotional systems distribution patterns and childhood trauma in youths’ BD with and without suicidal ideation (BD-IS, BD-NIS). Participants and setting: We assessed 289 participants, 103 youths with DSM-5 BD and 186 healthy controls (HCs). Methods: Primary emotional systems were obtained with Panksepp’s Affective Neuroscience Personality Scale (ANPS), and history of childhood trauma using the Childhood Trauma Questionnaire (CTQ). Suicidal ideation was assessed through the Columbia Suicide Scale for the Rating of Suicide Severity (C-SSRS). The associations with suicidal ideation were tested using two different multivariate models. Results: Over 48 % of participants reported lifetime suicidal ideation and differed on clinical variables from BD-NIS. According to the first model (Wilk’s Lambda = 0.72, p < 0.0001), BD-IS scored higher on Panksepp’s ANGER and lower on PLAY and CARE than BD-NIS. Both BD-SI and BD-NSI scored higher on ANGER and SEEK and lower on PLAY and CARE than HCs. BD-IS reported more emotional abuse than BD-NIS. They also reported more emotional, sexual, and physical abuse, and emotional neglect than HCs. Only ANGER (OR = 1.13, 95 % CI = 1.01–1.26, Wald = 5.72) and CTQ-Emotional abuse (OR = 1.26, 95 % C.I. = 1.04–1.52, Wald = 5.72) independently predicted suicidal ideation. Conclusions: Findings support the importance of assessing primary emotional systems and childhood trauma, in particular emotional abuse, in youths with BD at risk for suicide.
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- 2023
36. Predictors of polysubstance use in patients with severe alcohol use disorder: the role of reward craving
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Di Nicola, Marco, Pepe, Maria, Montanari, Silvia, Bonomo, L., Casile, F., Panaccione, I., Franza, Raffaella, Chieffo, Daniela Pia Rosaria, Martinotti, G., Addolorato, Giovanni, Janiri, Luigi, Sani, Gabriele, Di Nicola M. (ORCID:0000-0001-7457-0426), Pepe M., Montanari S., Franza R., Chieffo D., Addolorato G. (ORCID:0000-0002-1522-9946), Janiri L. (ORCID:0000-0002-1633-9418), Sani G. (ORCID:0000-0002-9767-8752), Di Nicola, Marco, Pepe, Maria, Montanari, Silvia, Bonomo, L., Casile, F., Panaccione, I., Franza, Raffaella, Chieffo, Daniela Pia Rosaria, Martinotti, G., Addolorato, Giovanni, Janiri, Luigi, Sani, Gabriele, Di Nicola M. (ORCID:0000-0001-7457-0426), Pepe M., Montanari S., Franza R., Chieffo D., Addolorato G. (ORCID:0000-0002-1522-9946), Janiri L. (ORCID:0000-0002-1633-9418), and Sani G. (ORCID:0000-0002-9767-8752)
- Abstract
Background: Different craving typologies (i.e., reward, relief, obsessive) have been identified in alcohol use disorder (AUD) but have been less investigated in specific populations like AUD patients with polysubstance use (PSU). The role of dysfunctional personality traits and reward pathways has been reported in both AUD and PSU. We hypothesized that patients with AUD-PSU might show a prevalent reward craving, alongside specific sociodemographic, clinical, and personality features, and aimed at investigating differences in 423 severe AUD outpatients with and without PSU. Methods: One hundred fifteen patients (27.1% of the sample, 67% males, 42 ± 11.6 years old) displayed PSU. Sociodemographic, clinical features and psychopathological/personality dimensions were assessed through: Craving Typologies Questionnaire (CTQ); Obsessive–Compulsive Drinking Scale (OCDS); UPPS-P Impulsive Behavior Scale (S-UPPS-P); Difficulties in Emotion Regulation Scale (DERS). A binomial logistic regression explored factors associated with PSU. Results: We found higher CTQ ‘reward’ scores (p < 0.001) in AUD-PSU patients, and a significant association between reward craving and PSU through logistic regression (OR:1.13; p = 0.005). Earlier AUD onset (p < 0.001), greater rates of binge drinking (p = 0.029), more legal problems (p = 0.015), but no significantly higher S-UPPS-S and DERS scores, were detected in AUD-PSU patients. Conclusions: Reward craving was associated with increased risk for PSU in severe AUD patients. Given AUD-PSU participants greater severity and detrimental treatment responses imputed to PSU, identifying prevalent craving types among risk factors for PSU in AUD may help to implement therapeutic strategies. Addressing neurobiological and behavioral mechanisms through combined psychotherapies, pharmacological and neuromodulation treatments could support tailored interventions with better long-term outcome.
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- 2023
37. Profile of cognitive abilities in spinal muscular atrophy type II and III: what is the role of motor impairment?
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Buchignani, B., Cicala, G., Moriconi, Federica, Ricci, M., Capasso, Anna, Coratti, Giorgia, Casiraghi, Jacopo Luca, Albamonte, E., Cristofani, P., Cutrona, Costanza, Pera, Maria Carmela, Antonaci, Laura, Roncoroni, C., Chieffo, Daniela Pia Rosaria, Sansone, V. A., Battini, Roberta, Pane, Marika, Mercuri, Eugenio Maria, Moriconi F., Capasso A., Coratti G. (ORCID:0000-0001-6666-5628), Casiraghi J., Cutrona C., Pera M. C. (ORCID:0000-0001-6777-1721), Antonaci L., Chieffo D., Battini R., Pane M. (ORCID:0000-0002-4851-6124), Mercuri E. (ORCID:0000-0002-9851-5365), Buchignani, B., Cicala, G., Moriconi, Federica, Ricci, M., Capasso, Anna, Coratti, Giorgia, Casiraghi, Jacopo Luca, Albamonte, E., Cristofani, P., Cutrona, Costanza, Pera, Maria Carmela, Antonaci, Laura, Roncoroni, C., Chieffo, Daniela Pia Rosaria, Sansone, V. A., Battini, Roberta, Pane, Marika, Mercuri, Eugenio Maria, Moriconi F., Capasso A., Coratti G. (ORCID:0000-0001-6666-5628), Casiraghi J., Cutrona C., Pera M. C. (ORCID:0000-0001-6777-1721), Antonaci L., Chieffo D., Battini R., Pane M. (ORCID:0000-0002-4851-6124), and Mercuri E. (ORCID:0000-0002-9851-5365)
- Abstract
There has recently been some concern on possible cognitive impairment in patients with Spinal Muscular Atrophy (SMA). The aim of this study was to assess cognitive profiles in type II and III SMA with a focus on individual indexes and possible correlations with motor function. 57 type II and III individuals, aged 3.5–17 years, were consecutively enrolled in a prospective, multicentric study. Cognitive function was assessed using age-appropriate Weschler Scales. Motor function was concomitantly assessed using disease-specific functional scales. Only 2 individuals (3%) had a intellectual disability of mild degree while the others were within normal range, with no significant difference in relation to SMA type, gender or functional status. While the overall quotients were mostly within normal range, some indexes showed wider variability. A significant positive medium correlation was found between Processing Speed Index and motor functional scores. Working memory had lower scores in type III patients compared to type II. Intellectual disability is uncommon in type II and III SMA. Motor functional abilities may play a role in some of the items contributing to the overall cognitive profile.
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- 2023
38. Social Stigma in Children with Long COVID.
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Buonsenso, Danilo, Camporesi, Anna, Morello, Rosa, De Rose, Cristina, Fracasso, Matteo, Chieffo, Daniela Pia Rosaria, and Valentini, Piero
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COVID-19 ,SOCIAL stigma ,MANN Whitney U Test ,MENTAL health ,SURVEYS ,PEARSON correlation (Statistics) ,QUESTIONNAIRES ,DESCRIPTIVE statistics ,CHI-squared test ,QUALITY of life ,DATA analysis software ,LONGITUDINAL method ,PSYCHOLOGICAL distress - Abstract
There is growing evidence that adults with Long COVID suffer from different sets of stigmata related to their condition. In children with Long COVID, this aspect has never been investigated. This study aims to investigate if children with Long COVID also experience stigma. Methods: Children with a previous SARS-CoV-2 infection evaluated at 3 month follow-ups in a pediatric post COVID unit were asked to fill in an online Long COVID Stigma Scale survey before they were assessed by a pediatrician. Doctors were unaware of children's responses when they performed a diagnosis of Long COVID or full recovery from previous infection, according to the World Health Organization definition of pediatric Long COVID. Responses to the Stigma scale were then compared in the two cohorts of children. Results: 224 patients responded to the questionnaire; 40 patients were diagnosed with Long COVID. Children with Long COVID significantly more frequently felt embarrassed about having Long COVID (p 0.035), felt embarrassed about having physical limitations (p < 0.001), felt they were valued less due to Long COVID (p 0.003), felt they were different from other peers due to Long COVID (p 0.033), felt significantly more frequently that people behaved differently towards them because they might be lying since the diagnosis of Long COVID (p 0.006), that they were less respected by others due to Long COVID (p 0.017), that other people thought that Long COVID is not a real disease (p 0.007), that other people thought that developing Long COVID is a sign of weakness (p 0.008), and that other people might judge them negatively due to their diagnosis of Long COVID (p < 0.001). Conclusions: Children with Long COVID, similar to adults, are suffering from stigmata due to their condition,. These data may have implication and should be used by the public, policy makers, and healthcare professionals regarding pediatric Long COVID. [ABSTRACT FROM AUTHOR]
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- 2023
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39. Eye Movement Desensitization and Reprocessing (EMDR) as a Possible Evidence-Based Rehabilitation Treatment Option for a Patient with ADHD and History of Adverse Childhood Experiences: A Case Report Study
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Guidetti, Clotilde, primary, Brogna, Patrizia, additional, Chieffo, Daniela Pia Rosaria, additional, Turrini, Ida, additional, Arcangeli, Valentina, additional, Rausa, Azzurra, additional, Bianchetti, Maddalena, additional, Rolleri, Elisa, additional, Santomassimo, Chiara, additional, Di Cesare, Gianluigi, additional, Ducci, Giuseppe, additional, Romeo, Domenico M., additional, and Brogna, Claudia, additional
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- 2023
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40. Integration of art and technology in personalized radiation oncology care: Experiences, evidence, and perspectives
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Casà, Calogero, primary, Dinapoli, Loredana, additional, Marconi, Elisa, additional, Chiesa, Silvia, additional, Cornacchione, Patrizia, additional, Beghella Bartoli, Francesco, additional, Bracci, Serena, additional, Salvati, Alessandra, additional, Scalise, Sara, additional, Colloca, Giuseppe Ferdinando, additional, Chieffo, Daniela Pia Rosaria, additional, Gambacorta, Maria Antonietta, additional, Valentini, Vincenzo, additional, and Tagliaferri, Luca, additional
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- 2023
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41. Art and digital technologies to support resilience during the oncological journey: The Art4ART project
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Tagliaferri, Luca, primary, Dinapoli, Loredana, additional, Casà, Calogero, additional, Colloca, Giuseppe Ferdinando, additional, Marazzi, Fabio, additional, Cornacchione, Patrizia, additional, Mazzarella, Ciro, additional, Masiello, Valeria, additional, Chiesa, Silvia, additional, Beghella Bartoli, Francesco, additional, Marconi, Elisa, additional, D'Oria, Marika, additional, Cesario, Alfredo, additional, Chieffo, Daniela Pia Rosaria, additional, Valentini, Vincenzo, additional, and Gambacorta, Maria Antonietta, additional
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- 2022
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42. The Italian Version of the Pediatric Quality of Life Inventory™ (Pedsql™) 3.0 Healthcare Satisfaction Hematology/oncology Module: Reliability and Validity in Radiation Oncology
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Marconi, Elisa, primary, Bartoli, Francesco Beghella, additional, Meldolesi, Elisa, additional, Mariani, Silvia, additional, Panza, Giulia, additional, Nardangeli, Alessia, additional, Dinapoli, Loredana, additional, Lees, Teresa Carmen, additional, Guido, Antonella, additional, Mastronuzzi, Angela, additional, Ruggiero, Antonio, additional, Gambacorta, Maria Antonietta, additional, Valentini, Vincenzo, additional, Balducci, Mario, additional, Chieffo, Daniela Pia Rosaria, additional, and Chiesa, Silvia, additional
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- 2022
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43. Language Development in Preschool Duchenne Muscular Dystrophy Boys
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Chieffo, Daniela Pia Rosaria, primary, Moriconi, Federica, additional, Mastrilli, Ludovica, additional, Lino, Federica, additional, Brogna, Claudia, additional, Coratti, Giorgia, additional, Altobelli, Michela, additional, Massaroni, Valentina, additional, Norcia, Giulia, additional, Ferraroli, Elisabetta, additional, Lucibello, Simona, additional, Pane, Marika, additional, and Mercuri, Eugenio, additional
- Published
- 2022
- Full Text
- View/download PDF
44. Psychological treatment of traumatic memories in COVID‐19 survivors
- Author
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Dinapoli, Loredana, primary, Ferrarese, Daniele, additional, Belella, Daniela, additional, Carnevale, Stefania, additional, Camardese, Giovanni, additional, Sani, Gabriele, additional, and Chieffo, Daniela Pia Rosaria, additional
- Published
- 2022
- Full Text
- View/download PDF
45. Cognitive function in DMD carriers: personal case series and literature review.
- Author
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Carraro, Laura, Iosca, Arianna, Dainesi, Maria Irene, Fusco, Sara, Chieffo, Daniela Pia Rosaria, Moriconi, Federica, d'Amario, Giulia, Pane, Marika, Mercuri, Eugenio, and Berardinelli, Angela
- Published
- 2023
- Full Text
- View/download PDF
46. Developmental Coordination Disorder and Most Prevalent Comorbidities: A Narrative Review
- Author
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Lino, Federica, primary and Chieffo, Daniela Pia Rosaria, additional
- Published
- 2022
- Full Text
- View/download PDF
47. Medi-Cinema: A Pilot Study on Cinematherapy and Cancer as A New Psychological Approach on 30 Gynecological Oncological Patients
- Author
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Chieffo, Daniela Pia Rosaria, primary, Lafuenti, Letizia, additional, Mastrilli, Ludovica, additional, De Paola, Rebecca, additional, Vannuccini, Sofia, additional, Morra, Marina, additional, Salvi, Fulvia, additional, Boškoski, Ivo, additional, Salutari, Vanda, additional, Ferrandina, Gabriella, additional, and Scambia, Giovanni, additional
- Published
- 2022
- Full Text
- View/download PDF
48. Posterior Fossa Tumor Rehabilitation: An Up-to-Date Overview
- Author
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Chieffo, Daniela Pia Rosaria, primary, Lino, Federica, additional, Arcangeli, Valentina, additional, Moriconi, Federica, additional, Frassanito, Paolo, additional, Massimi, Luca, additional, and Tamburrini, Gianpiero, additional
- Published
- 2022
- Full Text
- View/download PDF
49. Needleoscopic-assisted risk-reducing bilateral salpingo-oophorectomy in BRCA1/2 mutation carriers: Peri-operative outcomes and psychological impact
- Author
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Rosati, Andrea, primary, Fedele, Camilla, additional, Fagotti, Anna, additional, Lafuenti, Letizia, additional, Gioè, Alessandro, additional, Chieffo, Daniela Pia Rosaria, additional, Vizzielli, Giuseppe, additional, D'Ippolito, Giovanni, additional, Salutari, Vanda, additional, Paris, Ida, additional, Marchetti, Claudia, additional, Scambia, Giovanni, additional, and Gueli Alletti, Salvatore, additional
- Published
- 2022
- Full Text
- View/download PDF
50. Limited Access to Emotion Regulation Strategies Mediates the Association Between Positive Urgency and Sustained Binge Drinking in Patients with Alcohol Use Disorder
- Author
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Pepe, Maria, Di Nicola, Marco, Moccia, Lorenzo, Franza, Raffaella, Chieffo, Daniela Pia Rosaria, Addolorato, Giovanni, Janiri, Luigi, Sani, Gabriele, Pepe M., Di Nicola M. (ORCID:0000-0001-7457-0426), Moccia L., Franza R., Chieffo D., Addolorato G. (ORCID:0000-0002-1522-9946), Janiri L. (ORCID:0000-0002-1633-9418), Sani G. (ORCID:0000-0002-9767-8752), Pepe, Maria, Di Nicola, Marco, Moccia, Lorenzo, Franza, Raffaella, Chieffo, Daniela Pia Rosaria, Addolorato, Giovanni, Janiri, Luigi, Sani, Gabriele, Pepe M., Di Nicola M. (ORCID:0000-0001-7457-0426), Moccia L., Franza R., Chieffo D., Addolorato G. (ORCID:0000-0002-1522-9946), Janiri L. (ORCID:0000-0002-1633-9418), and Sani G. (ORCID:0000-0002-9767-8752)
- Abstract
Binge drinking (BD) represents a public health concern because of increasing prevalence, clinical implications, and social consequences. Determinants of BD have been mainly studied in non-clinical samples, but few data in patients with alcohol use disorder (AUD) are available. Our study aimed at identifying risk factors for BD in AUD patients. We evaluated 373 severe AUD outpatients, subdivided according to the presence of a sustained BD pattern in: non-binge drinkers (n = 256, M = 63.3%, 48.8 ± 10.7 years) and sustained binge drinkers (n = 117, M = 65%, 39.7 ± 9.6 years). We collected sociodemographic and clinical information and assessed impulsivity and emotion dysregulation using the short version of the UPPS-P Impulsive Behavior Scale (S-UPPS-P) and the Difficulties in Emotion Regulation Scale (DERS). We conducted a binomial logistic regression to investigate predictors for BD and a mediation analysis to test the effect of impulsivity and emotion dysregulation on BD. One hundred seventeen patients (31.4%) presented a sustained BD pattern. Positive urgency (OR: 2.235; p = 0.018) and limited access to emotion regulation strategies [DERS strategies (OR: 1.553; p = 0.004)] were risk factors for BD. The relationship between positive urgency and BD was significantly mediated by DERS strategies (p = 0.015; bootstrapped LLCI = 0.008, ULCI = 0.044). In our sample, positive urgency and limited access to emotion regulation strategies were risk factors for sustained BD in AUD patients. The effects of impulsivity on BD were mediated by difficulties in emotion regulation. BD patterns have been associated with poor response to treatment and worse outcome in AUD patients; however, the full impact of this problematic drinking pattern is still underinvestigated. Clarifying the underlying psychopathological dimensions is crucial to deliver targeted interventions.
- Published
- 2022
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