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Your search keyword '"Chibuikem Ikwuegbuenyi"' showing total 5 results
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5 results on '"Chibuikem Ikwuegbuenyi"'

1. The impact of COVID-19 pandemic on global neurosurgery collaborations

Author

Alvan-Emeka K. Ukachukwu, Nancy Abu-Bonsrah, Andreas Seas, Zoey Petitt, Romaric Waguia-Kouam, Samantha Ramos, Alyssa Edwards, Di D. Deng, Michael M. Haglund, Anthony T. Fuller, Amos Olufemi Adeleye, Misbahu Ahmad, Abenezer Tirsit Aklilu, Jeffrey Blount, Michael Dewan, Linda Domeisen, Geneviève Endalle, Ignatius Esene, Kristina Faulkner, David Hong, Corrado Iaccarino, Chibuikem Ikwuegbuenyi, James Johnston, David Kitya, Tsegazeab Laeke, Muhammad Raji Mahmud, Christine Muhumuza, Josephine Najjuma, Anil Nanda, Ahmed Negida, Frank Nketiah-Boakye, Wellingson Paiva, Kee Park, Mahmood Qureshi, Jack Rock, Brandon Rocque, Hamisi Shabani, Muhammad Tariq, Magnus Tisell, Teddy Totimeh, and André Yvan Zolo-Ossou

Subjects
Coronavirus disease 2019, COVID-19, Pandemic, Global neurosurgery, Collaborations, Low- and middle-income countries, Surgery, RD1-811, Neurology. Diseases of the nervous system, RC346-429
Published
2024
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2. Peripheral inflammation and neurodegeneration; a potential for therapeutic intervention in Alzheimer’s disease (AD), Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS)

Author

Lourdes Hanna, Edward Poluyi, Chibuikem Ikwuegbuenyi, Eghosa Morgan, and Grace Imaguezegie

Subjects
Neuroinflammation, Neurodegeneration, Intervention, Surgery, RD1-811, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Abstract Background Degeneration of the central nervous system (CNS), also known as neurodegeneration, describes an age-associated progressive loss of the structure and function of neuronal materials, leading to functional and mental impairments. Main body Neuroinflammation contributes to the continuous worsening of neurodegenerative states which are characterised by functional and mental impairments due to the progressive loss of the structure and function of neuronal materials. Some of the most common neurodegenerative diseases include Alzheimer’s disease (AD), Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS). Whilst neuroinflammation is a key contributor to the progression of such disease states, it is not the single cause as there are multiple factors which contribute. Theoretically, non-steroidal anti-inflammatory drugs (NSAIDs) have potential to target neuroinflammation to reduce the severity of disease states. Whilst some animal models investigating the effects of NSAIDs on the risk of neurodegenerative diseases have shown a beneficial effect, this is not always the case and a large number of clinical trials have not shown the same finding. Conclusion Further investigation using more advanced research methods is required to better understand neuroinflammatory pathways and understand if there is still a potential window for NSAID efficacy.

Published
2022
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4. Public Awareness, Knowledge of Availability, And Willingness to Use Neurosurgical Care Services in Africa: A Cross-Sectional E-Survey Protocol

Author

Chibuikem Ikwuegbuenyi, Daniel Safari Nteranya, Lorraine Arabang Sebopelo, Arsène Daniel Nyalundja, Michael Bamimore, Gideon Adegboyega, and Ulrick Sidney Kanmounye

Subjects
Protocol (science), Global neurosurgery, Odds ratio, Affect (psychology), Test (assessment), Likert scale, Willingness to use, Nursing, Health seeking behavior, Workforce, Africa, Protocol, Surgery, Psychology, Patient education
Abstract

Background: Barriers to care cause delays in seeking, reaching, and getting care. These delays affect low-and middle-income countries (LMICs), where 9 out of 10 LMIC inhabitants have no access to basic surgical care. Knowledge of healthcare utilization behavior within underserved communities is useful when developing and implementing health policies. Little is known about the neurosurgical health-seeking behavior of African adults. This study evaluates public awareness, knowledge of availability, and readiness for neurosurgical care services amongst African adults. Methodology: The cross-sectional study will be run using a self-administered e-survey hosted on Google Forms (Google, CA, USA) disseminated from 10th May 2021 to 10th June 2021. The Questionnaire would be in two languages, English and French. The survey will contain closed-ended, open-ended, and Likert Scale questions. The structured questionnaire will have four sections with 42 questions; Sociodemographic characteristics, Definition of neurosurgery care, Knowledge of neurosurgical diseases, practice and availability, and Common beliefs about neurosurgical care. All consenting adult Africans will be eligible. A minimum sample size of 424 will be used. Data will be analyzed using SPSS version 26 (IBM, WA, USA). Odds ratios and their 95% confidence intervals, Chi-Square test, and ANOVA will be used to test for associations between independent and dependent variables. A P-value

Published
2021

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