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228 results on '"Chiang, Cho-Han"'

5. Rate of Sodium Correction and Osmotic Demyelination Syndrome in Severe Hyponatremia: A Meta-Analysis

Author

See Xin Ya, Chang Yu-Cheng, Peng Chun-Yu, Wang Shih-Syuan, Chi Kuan-Yu, Chiang Cho-Hung, and Chiang Cho-Han

Subjects
hyponatremia, rapid correction, osmotic demyelination syndrome, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Current guidelines recommend limiting the rate of correction in patients with severe hyponatremia to avoid severe neurologic complications such as osmotic demyelination syndrome (ODS). However, published data have been conflicting. We aimed to evaluate the association between rapid sodium correction and ODS in patients with severe hyponatremia.

Published
2024
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17. Efficacy of cationic amphiphilic antihistamines on outcomes of patients treated with immune checkpoint inhibitors

Author

Chiang, Cho-Han, Chiang, Cho-Hung, Peng, Chun-Yu, Hsia, Yuan Ping, See, Xin Ya, Horng, Chuan-Sheng, Chang, Yu-Cheng, Shen, Xuan-Er, Wang, Shih-Syuan, Tsai, Tien-Chi, Chen, Yuan-Jen, Ma, Kevin Sheng-Kai, Chen, Brian Shiian, Luan, Yu-Ze, Tay, Soon-Tzeh, Shen, Chin-Hsuan, Chung, Katharine Ching, Chiang, Cho-Hsien, and Peng, Cheng-Ming

Published
2022
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24. The Association between Body Mass Index and Mortality in Breast Cancer Patients Receiving Pembrolizumab.

Author

Chiang, Cho-Han, Xu, Xiaocao, Shahid, Ahmed, Song, Junmin, Chi, Kuan-Yu, Chang, Yu-Cheng, Chang, Yu, Chiang, Cho-Hung, and Lin, Shuwen

Subjects
*EPIDERMAL growth factor receptors, *CANCER-related mortality, *IMMUNE checkpoint inhibitors, *BODY mass index, *PROPENSITY score matching
Abstract

Introduction: A higher body mass index (BMI) has been associated with a better response and overall survival in patients with lung cancer or melanoma receiving immune checkpoint inhibitors (ICIs). Pembrolizumab has been approved for the use of breast cancer, but its relationship with BMI on survival outcomes is unclear. Methods: We conducted a retrospective, propensity score-matched cohort study using the TriNetX Analytics Network database, which contains de-identified data from over 120 participating healthcare institutions. We included all adult female patients with breast cancer who received pembrolizumab. We excluded patients who were prescribed endocrine or human epidermal growth factor receptor 2-targeted therapies. We compared the 1-year all-cause mortality between patients who were overweight or obese (BMI ≥25 kg/m2) and those who were normal weight (BMI <25 kg/m2). We matched patients on predetermined variables including age, race, breast cancer-directed therapy, cardiovascular and diabetes medications, and underlying comorbidities. Results: We identified 1,628 eligible patients, of whom 1,163 had a BMI ≥25 kg/m2 and 465 had a BMI <25 kg/m2. After propensity score matching, 410 patients in each cohort were well balanced for demographics, breast cancer-directed therapy, and underlying comorbidities. The mean ages for patients with BMI ≥25 kg/m2 and BMI <25 kg/m2 were 56.7 ± 14.0 and 56.9 ± 15.0, respectively. Over a median follow-up of 1 year, 28 and 53 patients died in the BMI ≥25 kg/m2 and BMI <25 kg/m2 cohorts, respectively. Patients with BMI ≥25 kg/m2 had a 49% lower risk of all-cause mortality compared with those with BMI <25 kg/m2 (hazard ratio, 0.51 [95% CI: 0.33–0.81]). Conclusions: A BMI ≥25 kg/m2 was associated with a lower all-cause mortality among breast cancer patients receiving pembrolizumab. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Abstract 12767: Sodium-Glucose Cotransporter-2 Inhibitors Are Associated With Lower Risks of Hospitalization for Heart Failure and All-Cause Mortality in Patients With Diabetes Mellitus and Cancer

Author

Chiang, Cho Han, CHIANG, CHO HUNG, Chiang, Cho Hsien, Ma, Kevin, Peng, Chun-Yu, yuanping, HSIA, Horng, Chuan-Sheng, CHEN, CHENG-YING, Chang, Yu-Cheng, See, Xin Ya, Chen, Yuan-Jen, Wang, Shih-Syuan, Suero Abreu, Giselle A, Peterson, Linda R, Thavendiranathan, Paaladinesh, Armand, Philippe, Peng, Cheng-Ming, Shiah, Her-Shyong, and Neilan, Tomas G

Published
2022
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29. The impact of sodium‐glucose cotransporter‐2 inhibitors on outcome of patients with diabetes mellitus and colorectal cancer

Author

Chiang, Cho‐Han, primary, Chiang, Cho‐Hung, additional, Hsia, Yuan Ping, additional, Jaroenlapnopparat, Aunchalee, additional, Horng, Chuan‐Sheng, additional, Wong, Kit Yee, additional, Wang, Shih‐Syuan, additional, Chang, Yu‐Cheng, additional, Chen, Brian Shiian, additional, Luan, Yu‐Ze, additional, Wang, Chun‐Hao, additional, Neilan, Tomas G., additional, Chiang, Cho‐Hsien, additional, Peng, Cheng‐Ming, additional, and Shiah, Her‐Shyong, additional

Published
2024
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30. Impact of different corticosteroids on severe community-acquired pneumonia: a systematic review and meta-analysis

Author

See, Xin Ya, primary, Wang, Tsu Hsien, additional, Chang, Yu-Cheng, additional, Lo, Juien, additional, Liu, Weitao, additional, Choo, Cheryn Yu Wei, additional, Lee, Yu-Che, additional, Ma, Kevin Sheng Kai, additional, Chiang, Cho-Hsien, additional, Hsia, Yuan Ping, additional, Chiang, Cho-Hung, additional, and Chiang, Cho-Han, additional

Published
2024
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32. The comparative efficacy and safety of factor Xa inhibitors and warfarin for primary thromboprophylaxis in multiple myeloma patients undergoing immunomodulatory therapy.

Author

Chang, Yu‐Cheng, Song, Junmin, Chi, Kuan‐Yu, Gao, Wenli, Chang, Yu, Chiang, Cho‐Hung, Hsia, Yuan Ping, and Chiang, Cho‐Han

Subjects
VENOUS thrombosis, MULTIPLE myeloma, SAFETY factor in engineering, WARFARIN, GASTROINTESTINAL hemorrhage
Abstract

Summary: There are limited data on the optimal choice of anticoagulation in multiple myeloma (MM) patients receiving immunomodulatory drugs (IMiDs). We conducted a propensity score‐matched cohort study using the TriNetX database to compare the efficacy and safety of factor Xa inhibitors and warfarin in this patient population. Compared to warfarin, factor Xa inhibitors had a similar risk of deep vein thrombosis (hazard ratio [HR]: 1.11 [95% CI: 0.50–2.46]) or pulmonary embolism (HR: 1.08 [95% CI: 0.59–2.00]). There were no differences in the risk of gastrointestinal or intracranial bleeding. Factor Xa inhibitor‐treated patients had lower all‐cause mortality (HR: 0.56 [95% CI: 0.36–0.86]) compared with warfarin. These data suggest that factor Xa inhibitors had similar safety and efficacy compared with warfarin for MM patients on IMiDs. [ABSTRACT FROM AUTHOR]

Published
2024
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33. The Effect of Exercise on Cardiotoxicity in Women with Breast Cancer Receiving Anthracycline-Based Chemotherapy: A Systematic Review and Meta-Analysis.

Author

Chiang, Cho-Han, Chang, Yu-Cheng, Haw, Yulin, Tan, Jia Yi, Chiang, Cho-Hsien, Hsia, Yuan Ping, and Chiang, Cho-Hung

Subjects
*EXERCISE physiology, *MEDICAL information storage & retrieval systems, *WOMEN, *VENTRICULAR ejection fraction, *EXERCISE therapy, *BREAST tumors, *TREATMENT effectiveness, *META-analysis, *DESCRIPTIVE statistics, *CANCER chemotherapy, *SYSTEMATIC reviews, *MEDLINE, *CARDIAC output, *RESISTANCE training, *CARDIOTOXICITY, *ANTHRACYCLINES, *MEDICAL databases, *AEROBIC exercises, *ONLINE information services, *OXYGEN consumption, *CONFIDENCE intervals, *GLOBAL longitudinal strain
Abstract

Introduction: Breast cancer is the most common cancer in women with a 5-year survival over 90%. However, anthracycline-based chemotherapy causes significant cardiotoxicity often requiring discontinuation of chemotherapeutic regimen among breast cancer survivors. We conducted a systematic review and meta-analysis to evaluate the efficacy of exercise training in mitigating anthracycline-related cardiotoxicity among women with breast cancer. Methods: We searched PubMed, Embase, Cochrane Central Register of Controlled Trials, Web of Science, and Scopus databases. The outcomes of interest were left ventricular ejection fraction (LVEF), global longitudinal strain (GLS), early to atrial filling velocity (E/A) ratio, maximal oxygen consumption (VO2 max), and cardiac output (CO). We used the Cochrane risk-of-bias tool for randomized trials (RoB 2) to assess the risk of bias in individual studies. Results: We identified a total of 596 articles with 5 trials included in the final analysis. Exercise training was associated with an increase in VO2 max compared with no exercise training (mean difference, 3.95 [95% CI, 0.63–7.26]; I2 = 99.68%). Other cardiovascular outcomes such as LVEF (mean difference, 1.76 [95% CI, −1.95 to 5.46]; I2 = 99.44%), GLS (mean difference, 0.30 [95% CI, −0.49 to 1.10]; I2 = 96.63%), E/A ratio (mean difference, 0.05 [95% CI, −0.05 to 0.15]; I2 = 94.16%), and CO (mean difference, 0.38 [95% CI, −0.91 to 1.66]; I2 = 99.73%) are similar between patients who underwent exercise training and those who did not. Conclusions: Exercise was associated with an improvement in maximal oxygen uptake among women with breast cancer receiving anthracycline-based chemotherapy. [ABSTRACT FROM AUTHOR]

Published
2024
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39. Additional file 2 of Healthcare-associated infections in intensive care units in Taiwan, South Korea, and Japan: recent trends based on national surveillance reports

Author

Chiang, Cho-Han, Pan, Sung-Ching, Yang, Tyan-Shin, Matsuda, Keisuke, Kim, Hong Bin, Choi, Young Hwa, Hori, Satoshi, Wang, Jann-Tay, Sheng, Wang-Huei, Chen, Yee-Chun, Chang, Feng-Yee, and Chang, Shan-Chwen

Abstract

Table S2. National infection prevention and control policies and programs initiated, implemented or extended in Taiwan, South Korea, and Japan. (DOCX 59 kb)

Published
2023
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40. Additional file 1 of Healthcare-associated infections in intensive care units in Taiwan, South Korea, and Japan: recent trends based on national surveillance reports

Author

Chiang, Cho-Han, Pan, Sung-Ching, Yang, Tyan-Shin, Matsuda, Keisuke, Kim, Hong Bin, Choi, Young Hwa, Hori, Satoshi, Wang, Jann-Tay, Sheng, Wang-Huei, Chen, Yee-Chun, Chang, Feng-Yee, and Chang, Shan-Chwen

Abstract

Table S1. The number of participating hospitals and intensive care units of national healthcare-associated infection surveillance system in each country from 2008 to 2015. (DOCX 33 kb)

Published
2023
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41. Additional file 3 of Healthcare-associated infections in intensive care units in Taiwan, South Korea, and Japan: recent trends based on national surveillance reports

Author

Chiang, Cho-Han, Pan, Sung-Ching, Yang, Tyan-Shin, Matsuda, Keisuke, Kim, Hong Bin, Choi, Young Hwa, Hori, Satoshi, Wang, Jann-Tay, Sheng, Wang-Huei, Chen, Yee-Chun, Chang, Feng-Yee, and Chang, Shan-Chwen

Abstract

Table S3. Common causative pathogens of healthcare-associated urinary tract infections in intensive care units enrolled in national surveillance systems in Taiwan, South Korea, and Japan in 2015. (DOCX 36 kb)

Published
2023
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42. Additional file 5 of Healthcare-associated infections in intensive care units in Taiwan, South Korea, and Japan: recent trends based on national surveillance reports

Author

Chiang, Cho-Han, Pan, Sung-Ching, Yang, Tyan-Shin, Matsuda, Keisuke, Kim, Hong Bin, Choi, Young Hwa, Hori, Satoshi, Wang, Jann-Tay, Sheng, Wang-Huei, Chen, Yee-Chun, Chang, Feng-Yee, and Chang, Shan-Chwen

Abstract

Table S5. Common causative pathogens of healthcare-associated pneumonia in intensive care units enrolled in national surveillance systems in Taiwan, South Korea, and Japan in 2015. (DOCX 36 kb)

Published
2023
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43. Additional file 4 of Healthcare-associated infections in intensive care units in Taiwan, South Korea, and Japan: recent trends based on national surveillance reports

Author

Chiang, Cho-Han, Pan, Sung-Ching, Yang, Tyan-Shin, Matsuda, Keisuke, Kim, Hong Bin, Choi, Young Hwa, Hori, Satoshi, Wang, Jann-Tay, Sheng, Wang-Huei, Chen, Yee-Chun, Chang, Feng-Yee, and Chang, Shan-Chwen

Abstract

Table S4. Common causative pathogens of healthcare-associated bloodstream infections in intensive care units enrolled in national surveillance systems in Taiwan, South Korea, and Japan in 2015. (DOCX 36 kb)

Published
2023
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44. The impact of peroxisome proliferator‐activated receptor‐γ activating angiotensin receptor blocker on outcomes of patients receiving immunotherapy

Author

Chiang, Cho‐Han, primary, Chang, Yu‐Cheng, additional, Wang, Shih‐Syuan, additional, Chen, Yuan‐Jen, additional, See, Xin Ya, additional, Peng, Chun‐Yu, additional, Hsia, Yuan Ping, additional, Chiang, Cho‐Hsien, additional, Chiang, Cho‐Hung, additional, and Peng, Cheng‐Ming, additional

Published
2023
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50. Impact of sodium-glucose cotransporter-2 inhibitors on heart failure and mortality in patients with cancer

Author

Chiang, Cho-Han, primary, Chiang, Cho-Hung, additional, Chiang, Cho-Hsien, additional, Ma, Kevin Sheng-Kai, additional, Peng, Chun-Yu, additional, Hsia, Yuan Ping, additional, Horng, Chuan-Sheng, additional, Chen, Cheng-Ying, additional, Chang, Yu-Cheng, additional, See, Xin Ya, additional, Chen, Yuan-Jen, additional, Wang, Shih-Syuan, additional, Suero-Abreu, Giselle A, additional, Peterson, LR, additional, Thavendiranathan, Paaladinesh, additional, Armand, Philippe, additional, Peng, Cheng-Ming, additional, Shiah, Her-Shyong, additional, and Neilan, Tomas G, additional

Published
2022
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