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A pH-responsive supramolecular nanoparticles was constructed through the electrostatic interaction from anionic sulfobutyl ether-[beta]-cyclodextrin ([SBE.sub.7]-[beta]-CD) and two positively charged chitosan (CS-75% and CS-95%). The prepared nanoparticles were characterized by UV-vis absorption spectra, x-ray diffraction, dynamic light scattering, transmission electron microscopy, and zeta potential. It was found that the CS/[SBE.sub.7]-[beta]-CD nanoparticles can be disassembly by increasing pH value and reassembled by reducing to the original pH value. To explore the potential of the obtained nanoparticles as a drug delivery vehicle, a negatively charged anticardio cerebrovascular drug sodium ferulate (SF) was loaded. The result indicated that the SF could be efficiently encapsulated in its nanoparticle nucleus under simulated gastric conditions with lower pH (pH 2.0), while effective release is triggered in a simulated intestinal environment with higher pH (pH 8.5). The assembly/disassembly behavior and drug loading/release property make CS/[SBE.sub.7]-[beta]-CD nanoparticles promising candidates for pH stimulation responsive drug delivery system, which has a broad application prospect in the treatment of cardiovascular and cerebrovascular diseases, diabetes and other chronic diseases. KEYWORDS chitosan, pH-controlled release, sodium ferulate, sulfobutyl ether-[beta]- cyclodextrin, supramolecular nanoparticles, 1 | INTRODUCTION In the past few decades, controllable supramolecular nanoassembly constructed by several kinds of weak noncovalent interactions [1,2] have attracted considerable research interest because of their ease of [...]

The development of highly catalytic activity, low-cost and environmentally friendly catalysts is crucial for the use of advanced oxidation processes (AOPs) to treat organic pollutants. In this study, to reduce costs, enhance catalytic activity and avoid secondary pollution form metal ions, pomelo peel was used as raw material, combined with surface crystallization, carbon layer protection and heat treatment technology to effectively construct AOPs catalyst that can efficiently activate peroxymonosulfate (PMS) to degrade harmful organic pollutants. Under the optimal conditions, the Co/BC-PMS system can degrade about 100 % of tetracycline (TC, a spectral antibiotic) within 5 min, and the degradation rate of TC can still reach 100 % even if Co/BC (cobalt anchored on biochar) was reused for 6 times. The Co/BC-PMS system can resist complex environmental conditions, including acidic solution, alkaline solution, coexisting ions, different water quality, and is universal for the degradation of most organic pollutants. The integrated purification column with Co/BC as the core realizes the continuous and complete degradation of organic pollutants and has the ability of practical application. Radical capture and monitoring combined with density-functional-theory calculations confirmed that the Co(111) and amorphous CoO sites in Co/BC are the key to driving PMS to degrade organic pollutants, Co/BC can efficiently adsorb PMS and promote the dissociation of PMS into highly active OH, SO 4 - and 1 O 2 , and these reactive oxygen species jointly promote the degradation of organic pollutants. This study provides experimental support and theoretical insights for the design of efficient AOPs catalysts, and plays an important role in promoting the development of AOPs., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Inc. All rights reserved.)

In the crystal structure of the title compound, C(19)H(20)FN(2)O(3) (+)·C(2)F(3)O(2) (-), N-H⋯O and O-H⋯O hydrogen bonds link two cations and two anions into a 22-atom ring. These rings are further linked into a three dimensional network by weak C-H⋯O contacts.

Novel isomeric fluorine-boron complexes with donor-acceptor architecture have been efficiently synthesized and well characterized. Significant features, such as strong solid and liquid fluorescence, unusual large Stokes shifts, and lower LUMO levels and higher HOMO levels, are observed in these potential multifunctional molecules.