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1,315 results on '"Chi, Dennis S."'

3. Basket study of oral progesterone antagonist onapristone extended release in progesterone receptor-positive recurrent granulosa cell, low-grade serous ovarian cancer, or endometrioid endometrial cancer

Author

Andres, Sarah, Finch, Lindsey, Iasonos, Alexia, Zhou, Qin, Girshman, Jeffrey, Chhetri-Long, Rashmi, Green, Hunter, Jang, Dasom, O'Cearbhaill, Roisin, Kyi, Chrisann, Cohen, Seth, Friedman, Claire, Makker, Vicky, Chi, Dennis S., Sonoda, Yukio, Chiang, Sarah, Aghajanian, Carol, Weigelt, Britta, and Grisham, Rachel N.

Published
2024
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7. Mainstreaming in parallel with ovarian cancer tumor testing to improve genetic testing uptake

Author

Byrne, Maureen, Sia, Tiffany Y., Fong, Christopher, Khurram, Aliya, Waters, Michele, Kemel, Yelena M., Zhou, Qin, Ranganathan, Megha, Long Roche, Kara, Chi, Dennis S., Saban, Sally, Wu, Michelle, Varice, Nancy, Hamilton, Jada G., Carrot-Zhang, Jian, Abu-Rustum, Nadeem R., Iasonos, Alexia, Ellenson, Lora H., Mandelker, Diana, Weigelt, Britta, Brown, Carol L., Aghajanian, Carol, Stadler, Zsofia, and Liu, Ying L.

Published
2024
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8. Bridging Communication Gaps Between Radiologists, Referring Physicians, and Patients Through Standardized Structured Cancer Imaging Reporting: The Experience with Female Pelvic MRI Assessment Using O-RADS and a Simulated Cohort Patient Group

Author

Woo, Sungmin, Andrieu, Pamela Causa, Abu-Rustum, Nadeem R., Broach, Vance, Zivanovic, Oliver, Sonoda, Yukio, Chi, Dennis S., Aviki, Emeline, Ellis, Annie, Carayon, Pascale, Hricak, Hedvig, and Vargas, Hebert A.

Published
2024
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11. Pathogenic germline variants in non-BRCA1/2 homologous recombination genes in ovarian cancer: Analysis of tumor phenotype and survival

Author

Kahn, Ryan M., Selenica, Pier, Boerner, Thomas, Long Roche, Kara, Xiao, Yonghong, Sia, Tiffany Y., Maio, Anna, Kemel, Yelena, Sheehan, Margaret, Salo-Mullen, Erin, Breen, Kelsey E., Zhou, Qin, Iasonos, Alexia, Grisham, Rachel N., O’Cearbhaill, Roisin E., Chi, Dennis S., Berger, Michael F., Kundra, Ritika, Schultz, Nikolaus, Ellenson, Lora H., Stadler, Zsofia K., Offit, Kenneth, Mandelker, Diana, Aghajanian, Carol, Zamarin, Dmitriy, Sabbatini, Paul, Weigelt, Britta, and Liu, Ying L.

Published
2024
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12. Rectosigmoid resection by gynecologic oncologists versus colorectal surgeons: as long as it catches the mouse, does the color of the cat matter?

Author

Chang, Suk-Joon, Fotopoulou, Christina, Bristow, Robert E, Chi, Dennis S, and Cliby, William A

Subjects
Reproductive Medicine, Biomedical and Clinical Sciences, Animals, Cats, Colorectal Neoplasms, Cytoreduction Surgical Procedures, Female, Humans, Mice, Oncologists, Surgeons, Oncology and Carcinogenesis, Paediatrics and Reproductive Medicine, Oncology and carcinogenesis, Reproductive medicine
Published
2021

13. Impact of postoperative morbidity on outcomes in patients with advanced epithelial ovarian cancer undergoing intestinal surgery at the time of primary or interval cytoreductive surgery: A Memorial Sloan Kettering Cancer Center Team Ovary study

Author

Praiss, Aaron M., Hirani, Rahim, Zhou, Qin, Iasonos, Alexia, Sonoda, Yukio, Abu-Rustum, Nadeem R., Leitao, Mario M., Jr, Long Roche, Kara, Broach, Vance, Gardner, Ginger J., Chi, Dennis S., and Zivanovic, Oliver

Published
2023
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15. Leave it in the past - primary treatment modality for high-grade epithelial ovarian cancer is not associated with secondary cytoreduction outcomes: A Memorial Sloan Kettering Cancer Center Team Ovary study

Author

Sia, Tiffany Y., Manning-Geist, Beryl L., Ehmann, Sarah, Lavery, Jessica A., Luardo, Carrie, Praiss, Aaron, Iasonos, Alexia, Sonoda, Yukio, Grisham, Rachel N., Liu, Ying L., Broach, Vance, Zivanovic, Oliver, Long Roche, Kara, Gardner, Ginger J., and Chi, Dennis S.

Published
2023
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17. Patient-reported symptoms after minimally invasive hysterectomy and association with postoperative complications

Author

Feinberg, Jacqueline, Zivanovic, Oliver, Hannon, Michael, McCready, Taylor, Desai, Priyanka, Kim, Sarah H., Aviki, Emeline M., Mueller, Jennifer J., Jewell, Elizabeth L., Long Roche, Kara, Gardner, Ginger J., Chi, Dennis S., Sonoda, Yukio, Brown, Carol L., Abu-Rustum, Nadeem R., Cracchiolo, Jennifer R., Leitao, Mario M., Jr, and Broach, Vance

Published
2023
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18. Ovarian cancer mutational processes drive site-specific immune evasion

Author

Vázquez-García, Ignacio, Uhlitz, Florian, Ceglia, Nicholas, Lim, Jamie L. P., Wu, Michelle, Mohibullah, Neeman, Niyazov, Juliana, Ruiz, Arvin Eric B., Boehm, Kevin M., Bojilova, Viktoria, Fong, Christopher J., Funnell, Tyler, Grewal, Diljot, Havasov, Eliyahu, Leung, Samantha, Pasha, Arfath, Patel, Druv M., Pourmaleki, Maryam, Rusk, Nicole, Shi, Hongyu, Vanguri, Rami, Williams, Marc J., Zhang, Allen W., Broach, Vance, Chi, Dennis S., Da Cruz Paula, Arnaud, Gardner, Ginger J., Kim, Sarah H., Lennon, Matthew, Long Roche, Kara, Sonoda, Yukio, Zivanovic, Oliver, Kundra, Ritika, Viale, Agnes, Derakhshan, Fatemeh N., Geneslaw, Luke, Issa Bhaloo, Shirin, Maroldi, Ana, Nunez, Rahelly, Pareja, Fresia, Stylianou, Anthe, Vahdatinia, Mahsa, Bykov, Yonina, Grisham, Rachel N., Liu, Ying L., Lakhman, Yulia, Nikolovski, Ines, Kelly, Daniel, Gao, Jianjiong, Schietinger, Andrea, Hollmann, Travis J., Bakhoum, Samuel F., Soslow, Robert A., Ellenson, Lora H., Abu-Rustum, Nadeem R., Aghajanian, Carol, Friedman, Claire F., McPherson, Andrew, Weigelt, Britta, Zamarin, Dmitriy, and Shah, Sohrab P.

Published
2022
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19. Germline drivers of gynecologic carcinosarcomas

Author

Sia, Tiffany Y., Gordhandas, Sushmita B., Birsoy, Ozge, Kemel, Yelena, Maio, Anna, Salo-Mullen, Erin, Sheehan, Margaret, Hensley, Martee L., Rubinstein, Maria, Makker, Vicky, Grisham, Rachel N., O’Cearbhaill, Roisin E., Long Roche, Kara, Mueller, Jennifer J., Leitao, Mario M., Jr, Sonoda, Yukio, Chi, Dennis S., Abu-Rustum, Nadeem R., Berger, Michael F., Ellenson, Lora H., Latham, Alicia, Stadler, Zsofia, Offit, Kenneth, Aghajanian, Carol, Weigelt, Britta, Mandelker, Diana, and Liu, Ying L.

Published
2023
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20. Robotic Surgery in the Frail Elderly: Analysis of Perioperative Outcomes

Author

Aloisi, Alessia, Tseng, Jill, Kuhn, Theresa, Feinberg, Jacqueline, Chi, Dennis S, Brown, Carol L, Mueller, Jennifer J, Gardner, Ginger J, Zivanovic, Oliver, Jewell, Elizabeth L, Long Roche, Kara, Broach, Vance, Abu-Rustum, Nadeem R, and Leitao, Mario M

Subjects
Aging, Cardiovascular, Clinical Research, Patient Safety, Prevention, Management of diseases and conditions, 7.1 Individual care needs, Good Health and Well Being, Aged, Female, Frail Elderly, Frailty, Gynecologic Surgical Procedures, Humans, Neoplasms, Patient Readmission, Postoperative Complications, Risk Factors, Robotic Surgical Procedures, Treatment Outcome, Oncology and Carcinogenesis, Oncology & Carcinogenesis
Abstract

PurposeThe frail are considered at higher risk for unfavorable surgical outcomes (major complications/mortality). We assessed the safety of and outcomes associated with robotic surgery in the frail elderly undergoing gynecologic procedures.MethodsWe identified patients aged ≥ 65 years who underwent a robotic procedure between May 2007 and December 2016. Frailty was defined as the presence of at least three of five frailty factors-more than five comorbidities, low physical activity, weight loss, exhaustion, and fatigue. Perioperative outcomes were recorded. We compared variables among frail and non-frail patients and performed a multivariate logistic regression to detect variables associated with major complications (≥ grade 3) or 90-day mortality.ResultsWe identified 982 patients: 71 frail and 911 non-frail patients. Median age was 71 years. Median BMI was 29.8 kg/m2. Thirty-four patients (3.5%) had a 30-day readmission. Seventy-seven (7.8%) had a postoperative complication, of which 23 (2.3%) were major. Ninety-day mortality was 0.5%. There were significant differences with regard to age (P

Published
2020

21. Morbidity after secondary cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy for ovarian cancer: An analysis of a randomized phase II trial

Author

Praiss, Aaron M., Zhou, Qin, Iasonos, Alexia, Moukarzel, Lea, Dessources, Kimberly, Soldan, Krysten, Su, Katy, Sonoda, Yukio, Long Roche, Kara, Gardner, Ginger J., Troso-Sandoval, Tiffany, Tew, William P., Grisham, Rachel N., Chi, Dennis S., O'Cearbhaill, Roisin E., and Zivanovic, Oliver

Published
2023
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22. Intrathoracic surgery as part of primary cytoreduction for advanced ovarian cancer: Going to the next level – A Memorial Sloan Kettering Cancer Center study

Author

Kahn, Ryan M., McMinn, Erin, Yeoshoua, Effi, Boerner, Thomas, Zhou, Qin, Iasonos, Alexia, Long Roche, Kara, Zivanovic, Oliver, Gardner, Ginger J., Sonoda, Yukio, O'Cearbhaill, Roisin E., Grisham, Rachel N., Tew, William, Jones, David, Huang, James, Park, Bernard J., Abu-Rustum, Nadeem R., and Chi, Dennis S.

Published
2023
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23. Predicting outcomes in female germ cell tumors using a modified International Germ Cell Cancer Collaborative Group classification system to guide management

Author

Liu, Ying L., Manning-Geist, Beryl L., Knezevic, Andrea, Deng, Luxue, Bromberg, Maria, Funt, Samuel A., Meisel, Jane L., Zivanovic, Oliver, Long Roche, Kara, Sonoda, Yukio, Gardner, Ginger J., Grisham, Rachel N., O'Cearbhaill, Roisin E., Tew, William P., Abu-Rustum, Nadeem R., Chi, Dennis S., Aghajanian, Carol, and Feldman, Darren R.

Published
2023
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28. It's time to warm up to hyperthermic intraperitoneal chemotherapy for patients with ovarian cancer

Author

Zivanovic, Oliver, Chi, Dennis S, Filippova, Olga, Randall, Leslie M, Bristow, Robert E, and O'Cearbhaill, Roisin E

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Clinical Research, Clinical Trials and Supportive Activities, Patient Safety, Cancer, Orphan Drug, Rare Diseases, Ovarian Cancer, Female, Humans, Hyperthermia, Induced, Ovarian Neoplasms, Retrospective Studies, Hyperthermic intraperitoneal chemotherapy, HIPEC, Ovarian cancer, Debulking surgery, Paediatrics and Reproductive Medicine, Oncology & Carcinogenesis, Clinical sciences, Oncology and carcinogenesis, Reproductive medicine
Abstract

The peritoneal spread of ovarian cancer makes it a potential target for hyperthermic intraperitoneal chemotherapy (HIPEC). Intraperitoneal delivery exposes the tumor to concentrations of cytotoxic drugs much greater than with intravenous delivery, and in vitro studies have also shown that combining hyperthermia and platinum leads to an additive cytotoxic effect. Pharmacokinetic analyses have confirmed very high concentrations of cytotoxic drugs in the peritoneal cavity, with minimal systemic exposure and toxicity. The majority of historical data evaluating HIPEC in ovarian cancer are based on retrospective research, which included heterogeneous groups of patients and drugs used for HIPEC. Recent publications on the findings of prospective studies, including the first randomized trial in which the only difference in intervention was the addition of HIPEC with cisplatin to interval debulking surgery in stage III patients, have shown a benefit in favor of HIPEC. Yet, a recent prospective study from Korea did not find a benefit. Opponents of HIPEC have cited higher rates of complications with this approach, yet most of the serious adverse events observed are likely related to the surgery itself, and are comparable to the rates reported in studies evaluating cytoreductive surgery without HIPEC. Findings from a recent randomized controlled trial showed no delays in initiation or completion of postoperative chemotherapy in patients treated with HIPEC. A growing body of evidence is indicating that it might be time to seriously consider HIPEC as a complementary treatment at the time of cytoreductive surgery for patients with advanced-stage ovarian cancer in the setting of an experienced center. Yet, more research is needed to identify the population of patients who gain the most benefit from this therapy.

Published
2018

31. Uterine washings as a novel method for early detection of ovarian cancer: Trials and tribulations

Author

Sia, Tiffany Y., primary, Yaari, Zvi, additional, Feiner, Ron, additional, Smith, Evan, additional, Da Cruz Paula, Arnaud, additional, Selenica, Pier, additional, Doddi, Sital, additional, Chi, Dennis S., additional, Abu-Rustum, Nadeem R., additional, Levine, Douglas A., additional, Weigelt, Britta, additional, Fleisher, Martin, additional, Ramanathan, Lakshmi V., additional, Heller, Daniel A., additional, and Long Roche, Kara, additional

Published
2024
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37. Exploring the clinical significance of serous tubal intraepithelial carcinoma associated with advanced high-grade serous ovarian cancer: A Memorial Sloan Kettering Team Ovary Study

Author

Boerner, Thomas, Walch, Henry S., Nguyen, Bastien, Iasonos, Alexia, Zhou, Qin C., Schultz, Nikolaus, Chui, M. Herman, Grisham, Rachel N., Tew, William P., O'Cearbhaill, Roisin E., Aghajanian, Carol, Zivanovic, Oliver, Abu-Rustum, Nadeem R., Gardner, Ginger J., Sonoda, Yukio, Chi, Dennis S., and Long Roche, Kara

Published
2021
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39. Survival outcomes of acute normovolemic hemodilution in patients undergoing primary debulking surgery for advanced ovarian cancer: A Memorial Sloan Kettering Cancer Center Team Ovary study

Author

Boerner, Thomas, Tanner, Edward, Filippova, Olga, Zhou, Qin C., Iasonos, Alexia, Tew, William P., O'Cearbhaill, Roisin E., Grisham, Rachel N., Gardner, Ginger J., Sonoda, Yukio, Abu-Rustum, Nadeem R., Zivanovic, Oliver, Long Roche, Kara, Afonso, Anoushka M., Fischer, Mary, and Chi, Dennis S.

Published
2021
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41. Role of delayed interval debulking for persistent residual disease after more than 5 cycles of chemotherapy for primary advanced ovarian cancer. An international multicenter study

Author

Plett, Helmut, Filippova, Olga T., Garbi, Annalisa, Kommoss, Stefan, Rosendahl, Mikkel, Langstraat, Carrie, Phadnis, Saurabh, Muallem, Mustafa Zelal, Baert, Thaïs, Chi, Dennis S., Aletti, Giovanni Damiano, Taran, Florin-Andrei, Ramspott, Jan Philipp, Zivanovic, Oliver, du Bois, Andreas, Sonoda, Yukio, Gardner, Ginger, Traut, Alexander, Long Roche, Kara, and Harter, Philipp

Published
2020
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42. ARIA II: a randomized controlled trial of near-infrared Angiography during RectosIgmoid resection and Anastomosis in women with ovarian cancer.

Author

Leitao Jr, Mario M., Iasonos, Alexia, Tomberlin, Morgan, Moukarzel, Lea A., Price, Hannah, Bennetti, Gabrielle, Ramesh, Bhavani, Chi, Dennis S., Roche, Kara Long, Yukio Sonoda, Al-Niami, Ahmed, Mueller, Jennifer J., Gardner, Ginger J., Broach, Vance, Jewell, Elizabeth L., Kim, Sarah, Feinberg, Jacqueline, Abu-Rustum, Nadeem R., and Zivanovic, Oliver

Published
2024
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43. A pre-operative scoring model to estimate the risk of blood transfusion over an ovarian cancer debulking surgery (BLOODS score): a Memorial Sloan Kettering Cancer Center Team Ovary study.

Author

Kahn, Ryan M., Boerner, Thomas, Kim, Michael, Lam, Clarissa, Gordhandas, Sushmita, Yeoshoua, Effi, Zhou, Qin C., Iasonos, Alexia, Al-Niaimi, Ahmed, Gardner, Ginger J., Roche, Kara Long, Sonoda, Yukio, Zivanovic, Oliver, Grisham, Rachel N., Abu-Rustum, Nadeem R., and Chi, Dennis S.

Published
2024
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46. A multimodality triage algorithm to improve cytoreductive outcomes in patients undergoing primary debulking surgery for advanced ovarian cancer: A Memorial Sloan Kettering Cancer Center team ovary initiative

Author

Straubhar, Alli M., Filippova, Olga T., Cowan, Renee A., Lakhman, Yulia, Sarasohn, Debra M., Nikolovski, Ines, Torrisi, Jean M., Ma, Weining, Abu-Rustum, Nadeem R., Gardner, Ginger J., Sonoda, Yukio, Zivanovic, Oliver, Chi, Dennis S., and Long Roche, Kara

Published
2020
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50. Patient-reported outcomes after surgery for endometrial carcinoma: Prevalence of lower-extremity lymphedema after sentinel lymph node mapping versus lymphadenectomy

Author

Leitao, Mario M., Jr., Zhou, Qin C., Gomez-Hidalgo, Natalia R., Iasonos, Alexia, Baser, Ray, Mezzancello, Marissa, Chang, Kaity, Ward, Jae, Chi, Dennis S., Long Roche, Kara, Sonoda, Yukio, Brown, Carol L., Mueller, Jennifer J., Gardner, Ginger J., Jewell, Elizabeth L., Broach, Vance, Zivanovic, Oliver, Dowdy, Sean C., Mariani, Andrea, and Abu-Rustum, Nadeem R.

Published
2020
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