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This article, titled "Difficult Cases in Osteosarcoma: Tips on Not Missing the Tip of the Iceberg," aims to highlight the challenges in diagnosing osteosarcoma through a series of case studies. Osteosarcoma is the most common primary malignant bone tumor in young adults, and it is classified into eight categories based on its characteristics. While plain film radiographs can often help diagnose osteosarcoma, certain factors such as early detection, small lesions, and unusual locations can lead to a delayed diagnosis and confusion with benign conditions. The article emphasizes the importance of identifying subtle features of early disease and utilizing CT/MRI scans to accurately assess the extent of the tumor. [Extracted from the article]