Search

Your search keyword '"Cherry, Anne D."' showing total 34 results
Start Over Author "Cherry, Anne D."
34 results on '"Cherry, Anne D."'

4. Renal Failure and Dialysis

Author

Cherry, Anne D., Andrew, Benjamin Y., Privratsky, Jamie R., Stafford-Smith, Mark, Cheng, Davy C.H., editor, Martin, Janet, editor, and David, Tirone, editor

Published
2021
Full Text
View/download PDF

14. Contributors

Author

Abbott, Tom E.F., Absalom, Anthony R., Adelmann, Dieter, Allen, Paul D., Andreatta, Brock, Artime, Carlos A., Asnake, Betelehem, Azimaraghi, Omid, Barbeito, Atilio, Bartz, Raquel R., Berde, Charles B., Berger, Miles, Berra, Lorenzo, Bittner, Edward A., Braddock, Clarence, III, Breyer, Kristine E.W., Bruins, Benjamin B., Brull, Richard, Brull, Sorin J., Buck, David Winthrop, Burkhardt, Daniel H., III, Camporesi, Enrico M., Campos, Javier, Castro de Oliveira, Bruna M., Cereda, Maurizio, Chang, Joyce, Chang, Marvin, Chen, Catherine L., Cherry, Anne D., Chitilian, Hovig V., Choukalas, Christopher, Chung, Mabel, Cobert, Julien, Cohen, Neal H., Colquhoun, Douglas A., Cotter, Sarah, Cudemus, Gaston, Cumpstey, Andrew F., Dabski, Matthew, Dalia, Adam A., Davidson, Andrew, Davis, Nicholas A., de Boer, Hans D., Deiner, Stacie, Drobish, Julie K., Drummond, John C., Dudley, Matthew T., Eckmann, David M., Edwards, Mark R., Ehie, Odinakachukwu, Eikermann, Matthias, Eleveld, Douglas J., Elkassabany, Nabil M., Engelhard, Kristin, Eriksson, Lars I., Evered, Lisbeth, Evgenov, Oleg V., Fagerlund, Malin Jonsson, Fang, Zhuang T., Fassbender, Philipp, Ferschl, Marla B., Finlayson, Emily, Fitzsimons, Michael, Fleisher, Lee A., Forman, Stuart A., Franks, Nicholas P., Fuchs-Buder, Thomas, Fukuda, Kazuhiko, Gabrielli, Elizabeth Mahanna, Gainsburg, Daniel, Galvagno, Samuel M., Jr, Gaskell, Amy, Gebauer, Sarah, Gerlach, Rebecca M., Gianni, Stefano, Goren, Or, Gray, Andrew T., Grocott, Michael P.W., Gropper, Michael A., Hagberg, Carin A., Haylock-Loor, Carolina, Hellman, Judith, Hemmings, Hugh C., Jr, Hendel, Simon Andrew, Hewson, David W., Hight, Darren, Horvath, Ryan, Hurley, Robert W., Hyman, Jaime B., Irefin, Samuel A., Ishizawa, Yumiko, Jackson, Alexander I.R., Jiang, Yandong, Johnson, Daniel W., Johnson, Ken B., Johnson, Rebecca L., Johnson-Akeju, Oluwaseun, Jooste, Edmund H., Kaczka, David W., Kaur, Gunisha, Kessler, Jens, Keyes, Mary, Khan, Fauzia, Kheterpal, Sachin, Kilbaugh, Todd J., Kim, Tae Kyun, Ko, Nerissa U., Kopf, Andreas, Kopp, Sandra L., Kronish, Kate, Kumar, Avinash B., Lam, Arthur M., Lancman, Benn Morrie, Lane-Fall, Meghan Brooks, Law, Tyler, Legrand, Matthieu, Lemkuil, Brian P., Leslie, Kate, Liang, Yafen, Liew, Elaine Chiewlin, Lilaonitkul, Maytinee, Lipnick, Michael S., Lirk, Philipp, Lisco, Steven J., Liu, Kathleen D., Liu, Linda L., Lucero, Jennifer, Macfarlane, Alan J.R., Mahajan, Aman, Mahmood, Feroze, Malhotra, Gaurav, Malhotra, Vinod, Mark, Jonathan, Martinez, Rebecca H., Martyn, J.A. Jeevendra, Mashour, George A., McCarthy, Grace C., Meistelman, Claude, Vidal Melo, Marcos F., Michelow, Marilyn, Moon, Richard E., Mulvoy, William P., Neelankavil, Jacques Prince, Neligan, Patrick J., Nemes, Reka, Njoku, Dolores B., Nozari, Ala, Obara, Shinju, Sung-jin Ok, Michale, Oprea, Adriana D., Orser, Beverley A., Palaniappa, Nandini C., Pamnani, Anup, Panigrahi, Anil K., Parotto, Matteo, Pasternak, L. Reuven, Patel, Anil, Patel, Piyush M., Pearce, Robert A., Perouansky, Misha, Pessah, Isaac N., Philip, Beverly, Pino, Richard M., Prakash, Arun, Pryor, Kane O., Reekers, Marije, Renew, J. Ross, Richards, Justin E., Robitaille, Mark, Rodriguez-Diaz, Cesar, Rollins, Mark D., Ross, Patrick A., Roth, Steven, Rubertsson, Sten, Sabouri, A. Sassan, Sarwar, Muhammad F., Schenning, Katie J., Schnaubelt, Elizabeth R., Schroeder, Becky, Searles, Bruce E., Sendagire, Cornelius, Seubert, Christoph N., Shafer, Steven L., Shah, Ann Cai, Shah, Nirav J., Shalabi, Ahmed, Sharma, Anshuman, Sharpe, Emily E., Shelton, Kenneth T., Shore-Lesserson, Linda, Sikorski, Robert A., Sitsen, Elske, Sjöberg, Folke, Sleigh, Jamie, Slinger, Peter, Sonny, Abraham, Soriano, Sulpicio G., Steadman, Randolph H., Stein, Christoph, Steurer, Marc P., Streckenbach, Scott, Struys, Michel M.R.F., Sun, Lena S., Suresh, Santhanam, Sviggum, Hans P., Sweitzer, Bobbie Jean, Takeda, Shinhiro, Tameze, Yasmine, Thilen, Stephan R., Tran, Tina, Tsui, Ban, Van Norman, Gail, Vaporidi, Katerina, Varughese, Anna Mary, Vazquez, Rafael, Vutskits, Laszlo, Vuyk, Jaap, Weston, Stephen D., Whitlock, Elizabeth L., Wijeysundera, Duminda N., Wilson, Sylvia H., Wray, Christopher, Wu, Christopher L., Xia, Victor W., Yemul Golhar, Shweta Rahul, Yen, Albert, Yu, Xiaobing, Zhao, Jing, and Zhou, Jie

Published
2025
Full Text
View/download PDF

20. Carbon monoxide, skeletal muscle oxidative stress, and mitochondrial biogenesis in humans

Author

Rhodes, Michael A., Carraway, Martha Sue, Piantadosi, Claude A., Reynolds, Crystal M., Cherry, Anne D., Wester, T.E., Natoli, Michael J., Massey, E. Wayne, Moon, Richard E., and Suliman, Hagir B.

Subjects
Carbon monoxide -- Health aspects, Mitochondria -- Properties, Oxidative stress -- Diagnosis, Oxygen consumption -- Measurement, Muscles -- Properties, Superoxide dismutase -- Properties, Biological sciences
Abstract

Given that the physiology of heine oxygenase-1 (HO-1) encompasses mitochondrial biogenesis, we tested the hypothesis that the HO-1 product, carbon monoxide (CO), activates mitochondrial biogenesis in skeletal muscle and enhances maximal oxygen uptake ([??].sub.2max]) in humans. In l0 healthy subjects, we biopsied the vastus lateralis and performed [??].sub.2max] tests followed by blinded randomization to air or CO breathing (1 h/day at 100 parts/million for 5 days), a contralateral muscle biopsy on day 5, and repeat [??].sub.2max] testing on day 8. Six independent subjects underwent CO breathing and two muscle biopsies without exercise testing. Molecular studies were performed by real-time RT-PCR, Western blot analysis, and immunochemistry. After [??].sub.2max] testing plus CO breathing, significant increases were found in mRNA levels for nuclear respiratory factor-1, peroxisome proliferator-activated receptor-[gamma] coactivator-1[alpha], mitochondrial transcription factor-A (Tfam), and DNA polymerase [gamma](Pol[gamma]) with no change in mitochondrial DNA (mtDNA) copy number or [??].sub.2max]. Levels of myosin heavy chain I and nuclear-encoded HO-1, superoxide dismutase-2, citrate synthase, mitofusin-1 and -2, and mitochondrial-encoded cytochrome oxidase subunit-I (COX-I) and ATPase-6 proteins increased significantly. None of these responses were reproduced by [??].sub.2max] testing alone, whereas CO alone increased Tfam and Pol[gamma] mRNA, and COX-I, ATPase-6, mitofusin-2, HO-1, and superoxide dismutase protein. These findings provide evidence linking the HO/CO response involved in mitochondrial biogenesis in rodents to skeletal muscle in humans through a set of responses involving regulation of the mtDNA transcriptosome and mitochondrial fusion proteins autonomously of changes in exercise capacity. heme oxygenase-1; superoxide dismutase-2; peroxisome proliferator-activated receptor-[gamma] coactivator-1[alpha]; nuclear respiratory factor-1; oxygen uptake

Published
2009

23. Colaboradores

Author

Absalom, Anthony Ray, Acker, Leah, Akeju, Oluwaseun, Albrecht, Meredith A., Aldrich, J. Matthew, Allen, Paul Denney, Arendt, Katherine W., Artime, Carlos A., Barbeito, Atilio, Bateman, Brian, Berde, Charles B., Berg, Sheri, Berger, Miles, Bittner, Edward A., Blair, James L., Bokoch, Michael P., Braehler, Matthias R., Breyer, Kristine E.W., Brown, Emery N., Brull, Richard, Brull, Sorin J., Buck, David Winthrop, Burkhardt, Daniel H., III, Camporesi, Enrico M., Campos, Javier H., Chan, Vincent W.S., Chang, Joyce, Chen, Catherine L., Chen, Lucy Lin, Cherry, Anne D., Chitilian, Hovig V., Choukalas, Christopher, Chung, Mabel, Claudius, Casper, Cohen, Neal H., Colquhoun, Douglas A., Crawford, Lane C., Crowley, Jerome C., Cudemus, Gaston, Culley, Deborah J., Cumpstey, Andrew F., Davidson, Andrew, Davis, Nicholas A., de Boer, Hans D., Deiner, Stacie, Dieckmann, Peter, Donovan, Anne L., Drummond, John C., Dudley, Matthew, Eckenhoff, Roderic G., Eckmann, David M., Edwards, Mark R., Eikermann, Matthias, Elkassabany, Nabil M., Ellis, Dan B., Engelhard, Kristin, Eriksson, Lars I., Evered, Lisbeth, Evgenov, Oleg V., Fagerlund, Malin Jonsson, Fang, Zhuang T., Ferschl, Marla B., Finlayson, Emily, Fitzsimons, Michael, Fleisher, Lee A., Forman, Stuart A., Franks, Nicholas P., Fuchs-Buder, Thomas, Fukuda, Kazuhiko, Gaba, David M., Gainsburg, Daniel, Galvagno, Samuel Michael, Jr., Gebauer, Sarah, Gelb, Adrian W., Gray, Andrew T., Greeley, William J., Grissom, Thomas E., Grocott, Michael P.W., Gropper, Michael A., Hadler, Rachel A., Hagberg, Carin A., Hanidziar, Dusan, Hedenstierna, Göran, Heitmiller, Eugenie S., Hemmings, Hugh C., Hendel, Simon Andrew, Hurley, Robert W., Irefin, Samuel A., Ishizawa, Yumiko, Jackson, Alexander I.R., Jiang, Yandong, Johnson, Daniel W., Johnson, Ken B., Johnson, Rebecca L., Jooste, Edmund H., Kaczka, David W., Kalkman, Cor J., Kavanagh, Brian P., Kessler, Jens, Keyes, Mary A., Kheterpal, Sachin K., Kiefer, Jesse, Kilbaugh, Todd J., Kim, Tae Kyun, Kindler, Christoph H., Klinck, John R., Ko, Nerissa U., Kolbe, Michaela, Kopf, Andreas, Kopp, Sandra L., Krajewski, Megan L., Kronish, Kate, Kumar, Avinash B., Kuo, Alexander S., Lai, Yvonne Y., Lam, Arthur, Lancman, Benn Morrie, Lane-Fall, Meghan Brooks, Lemkuil, Brian P., Leslie, Kate, Lewis, Jason M., Liang, Yafen, Liew, Elaine Chiewlin, Lipnick, Michael S., Lirk, Philipp, Lisco, Steven J., Liu, Kathleen D., Liu, Linda L., Lönnqvist, Per-Anne, Macfarlane, Alan J.R., Machovec, Kelly, Mahajan, Aman, Mahla, Michael, Mahmood, Feroze, Malhotra, Anuj, Malhotra, Gaurav, Malhotra, Vinod, Mao, Jianren, Mark, Jonathan, Mark, Laurie O., Jeevendra Martyn, J.A., Mashour, George A., McAuliffe, John J., III, Meistelman, Claude, Vidal Melo, Marcos F., Michelow, Marilyn, Miller, Ronald D., Moon, Richard E., Mulvoy, William P., III, Murphy, Glenn, Mythen, Monty, Neelankavil, Jacques Prince, Neligan, Patrick, Neuman, Mark D., Njoku, Dolores B., Nozari, Ala, Obara, Shinju, Oberfrank, Stephanie Maria, Pamnani, Anup, Panigrahi, Anil K., Patel, Anil, Patel, Piyush M., Pearce, Robert A., Pearse, Rupert M., Perouansky, Misha, Pessah, Isaac Ness, Philip, Beverly K., Pino, Richard M., Pryor, Kane O., Purdon, Patrick L., Rall, Marcus, Ramsay, James G., Reekers, Marije, Roizen, Michael F., Rollins, Mark D., Rosenbaum, Stanley H., Ross, Patrick, Roth, Steven, Rubertsson, Sten, Sabouri, A. Sassan, Sarwar, Muhammad F., Schroeder, Becky, Schumacher, Mark, Searles, Bruce E., Seubert, Christoph N., Shafer, Steven L., Shah, Ann Cai, Shah, Nirav J., Shalabi, Ahmed, Sharpe, Emily E., Shelton, Kenneth, Shen, Shiqian, Shore-Lesserson, Linda, Sitsen, Elske, Sjöberg, Folke, Skues, Mark A., Slinger, Peter, Smith, Ian, Solt, Ken, Sonny, Abraham, Steadman, Randolph H., Stein, Christoph, Steurer, Marc P., Stone, Marc E., Struys, Michel MRF, Sun, Lena S., Suresh, Santhanam, Turnbull, John H., Van Norman, Gail A., Varughese, Anna Mary, Vazquez, Rafael, Vutskits, Laszlo, Vuyk, Jaap, Weston, Stephen D., Whitlock, Elizabeth L., Wiener-Kronish, Jeanine P., Wijeysundera, Duminda N., Wray, Christopher L., Wu, Christopher L., Xia, Victor W., Zaremba, Sebastian, Zhou, Jie, and Zwass, Maurice S.

Published
2021
Full Text
View/download PDF

25. Contributors

Author

Absalom, Anthony Ray, Acker, Leah, Akeju, Oluwaseun, Albrecht, Meredith A., Aldrich, J. Matthew, Allen, Paul Denney, Arendt, Katherine W., Artime, Carlos A., Barbeito, Atilio, Bateman, Brian, Berde, Charles B., Berg, Sheri, Berger, Miles, A. Bittner, Edward, Blair, James L., Bokoch, Michael P., Braehler, Matthias R., Breyer, Kristine E.W., Brown, Emery N., Brull, Richard, Brull, Sorin J., Buck, David Winthrop, Burkhardt, Daniel H., III, Camporesi, Enrico M., Campos, Javier H., Chan, Vincent W.S., Chang, Joyce, Chen, Catherine L., Chen, Lucy Lin, Cherry, Anne D., Chitilian, Hovig V., Choukalas, Christopher, Chung, Mabel, Claudius, Casper, Cohen, Neal H., Colquhoun, Douglas A., Crawford, Lane C., Crowley, Jerome C., Cudemus, Gaston, Culley, Deborah J., Cumpstey, Andrew F., Davidson, Andrew, Davis, Nicholas A., de Boer, Hans D., Deiner, Stacie, Dieckmann, Peter, Donovan, Anne L., Drummond, John C., Dudley, Matthew, G. Eckenhoff, Roderic, Eckmann, David M., Edwards, Mark R., Eikermann, Matthias, Elkassabany, Nabil M., Ellis, Dan B., Engelhard, Kristin, Eriksson, Lars I., Evered, Lisbeth, Evgenov, Oleg V., Fagerlund, Malin Jonsson, Fang, Zhuang T., Ferschl, Marla B., Finlayson, Emily, Fitzsimons, Michael, Fleisher, Lee A., Forman, Stuart A., Franks, Nicholas P., Fuchs-Buder, Thomas, Fukuda, Kazuhiko, Gaba, David M., Gainsburg, Daniel, Galvagno, Samuel Michael, Jr., Gebauer, Sarah, Gelb, Adrian W., Gray, Andrew T., Greeley, William J., Grissom, Thomas E., Grocott, Michael P.W., A. Gropper, Michael, Hadler, Rachel A., Hagberg, Carin A., Hanidziar, Dusan, Hedenstierna, Göran, Heitmiller, Eugenie S., Hemmings, Hugh C., Hendel, Simon Andrew, Hurley, Robert W., A. Irefin, Samuel, Ishizawa, Yumiko, Jackson, Alexander I.R., Jiang, Yandong, Johnson, Daniel W., Johnson, Ken B., Johnson, Rebecca L., Jooste, Edmund H., Kaczka, David W., Kalkman, Cor J., Kavanagh, Brian P., Kessler, Jens, Keyes, Mary A., Kheterpal, Sachin K., Kiefer, Jesse, Kilbaugh, Todd J., Kim, Tae Kyun, Kindler, Christoph H., Klinck, John R., Ko, Nerissa U., Kolbe, Michaela, Kopf, Andreas, Kopp, Sandra L., Krajewski, Megan L., Kronish, Kate, Kumar, Avinash B., Kuo, Alexander S., Lai, Yvonne Y., Lam, Arthur, Lancman, Benn Morrie, Lane-Fall, Meghan Brooks, Lemkuil, Brian P., Leslie, Kate, Lewis, Jason M., Liang, Yafen, Liew, Elaine Chiewlin, Lipnick, Michael S., Lirk, Philipp, Lisco, Steven J., Liu, Kathleen D., Liu, Linda L., Lönnqvist, Per-Anne, Macfarlane, Alan J.R., Machovec, Kelly, Mahajan, Aman, Mahla, Michael, Mahmood, Feroze, Malhotra, Anuj, Malhotra, Gaurav, Malhotra, Vinod, Mao, Jianren, Mark, Jonathan, Mark, Laurie O., Martyn, J.A. Jeevendra, Mashour, George A., McAuliffe, John J., III, Meistelman, Claude, Vidal Melo, Marcos F., Michelow, Marilyn, Miller, Ronald D., Moon, Richard E., Mulvoy, William P., III, Murphy, Glenn, Mythen, Monty, Neelankavil, Jacques Prince, Neligan, Patrick, Neuman, Mark D., Njoku, Dolores B., Nozari, Ala, Obara, Shinju, Oberfrank, Stephanie Maria, Pamnani, Anup, Panigrahi, Anil K., Patel, Anil, M. Patel, Piyush, Pearce, Robert A., Pearse, Rupert M., Perouansky, Misha, Pessah, Isaac Ness, Philip, Beverly K., Pino, Richard M., Pryor, Kane O., Purdon, Patrick L., Rall, Marcus, Ramsay, James G., Reekers, Marije, Roizen, Michael F., Rollins, Mark D., Rosenbaum, Stanley H., Ross, Patrick, Roth, Steven, Rubertsson, Sten, Sabouri, A. Sassan, Sarwar, Muhammad F., Schroeder, Becky, Schumacher, Mark, E. Searles, Bruce, Seubert, Christoph N., Shafer, Steven L., Shah, Ann Cai, Shah, Nirav J., Shalabi, Ahmed, Sharpe, Emily E., Shelton, Kenneth, Shen, Shiqian, Shore-Lesserson, Linda, Sitsen, Elske, Sjöberg, Folke, Skues, Mark A., Slinger, Peter, Smith, Ian, Solt, Ken, Sonny, Abraham, Steadman, Randolph H., Stein, Christoph, Steurer, Marc P., Stone, Marc E., Struys, Michel MRF, Sun, Lena S., Suresh, Santhanam, Turnbull, John H., Van Norman, Gail A., Varughese, Anna Mary, Vazquez, Rafael, Vutskits, Laszlo, Vuyk, Jaap, Weston, Stephen D., Whitlock, Elizabeth L., Wiener-Kronish, Jeanine P., Wijeysundera, Duminda N., Wray, Christopher L., Wu, Christopher L., Xia, Victor W., Zaremba, Sebastian, Zhou, Jie, and Zwass, Maurice S.

Published
2020
Full Text
View/download PDF

27. Swimming-Induced Pulmonary Edema

Author

Moon, Richard E., primary, Martina, Stefanie D., additional, Peacher, Dionne F., additional, Potter, Jennifer F., additional, Wester, Tracy E., additional, Cherry, Anne D., additional, Natoli, Michael J., additional, Otteni, Claire E., additional, Kernagis, Dawn N., additional, White, William D., additional, and Freiberger, John J., additional

Published
2016
Full Text
View/download PDF

32. Platelet Counts and Postoperative Stroke After Coronary Artery Bypass Grafting Surgery

Author

Karhausen, Jörn A., Smeltz, Alan M., Akushevich, Igor, Cooter, Mary, Podgoreanu, Mihai V., Stafford-Smith, Mark, Martinelli, Susan M., Fontes, Manuel L., Kertai, Miklos D., Aronson, Solomon, Bartz, Raquel R., Bottiger, Brandi A., Cherry, Anne D., Colin, Brian J., Del Rio, J. Mauricio, Fierro, Michael, Ghadimi, Kamrouz, Guinn, Nicole R., Iboaya, Ehimemen, Jones-Haywood, Mandisa, Klinger, Rebecca Y., Konoske, Ryan, Levy, Jerrold H., Lombard, F. Willem, Maisonave, Yasmin, Manning, Michael W., Mathew, Joseph P., Maxwell, Corry D., McCarthy, Grace C., Newman, Mark F., Nicoara, Alina, Quinones, Quintin J., Swaminathan, Madhav, Thompson, Annemarie, Vega, Eleanor A., Welsby, Ian J., Balajonda, Narai, Bisanar, Tiffany, Brassard, Rachele, Funk, Bonita L., Hall, Roger L., Lane, Kathleen, Li, Yi-Ju, Mbocchi, Galdwell, Pecora, Greg, Pender, Michelle, Phillips-Bute, Barbara, Solon, Prometheus T., Toulgoat-Dubois, Yanne, Waweru, Peter, White, William D., Collins, Kevin, Shearer, Ian, Smigla, Greg, D’Amico, Thomas A., Daneshmand, Mani A., Davis, R. Duane, Gaca, Jeffrey G., Glower, Donald D., Haney, John, Harpole, R. David, Hartwig, Matthew G., Hughes, G. Chad, Jaquiss, Robert D.B., Lin, Shu S., Lodge, Andrew J., Milano, Carmelo A., Onaitis, Mark W., Schroeder, Jacob N., Smith, Peter K., and Tong, Betty C.

Abstract

Published ahead of print June 17, 2017.

Published
2017
Full Text
View/download PDF

34. Hypercapnia in diving: a review of CO₂ retention in submersed exercise at depth.

Author

Dunworth SA, Natoli MJ, Cooter M, Cherry AD, Peacher DF, Potter JF, Wester TE, Freiberger JJ, and Moon RE

Subjects
Adult, Carbon Dioxide administration & dosage, Carbonic Anhydrases metabolism, Cognition Disorders etiology, Female, Humans, Hyperoxia complications, Male, Partial Pressure, Pulmonary Gas Exchange physiology, Pulmonary Ventilation physiology, Respiratory Dead Space physiology, Symptom Assessment, Carbon Dioxide blood, Diving adverse effects, Hypercapnia etiology, Respiration
Abstract

Carbon dioxide (CO₂) retention, or hypercapnia, is a known risk of diving that can cause mental and physical impairments leading to life-threatening accidents. Often, such accidents occur due to elevated inspired carbon dioxide. For instance, in cases of CO₂ elimination system failures during rebreather dives, elevated inspired partial pressure of carbon dioxide (PCO₂) can rapidly lead to dangerous levels of hypercapnia. Elevations in PaCO₂ (arterial pressure of PCO₂) can also occur in divers without a change in inspired PCO₂. In such cases, hypercapnia occurs due to alveolar hypoventilation. Several factors of the dive environment contribute to this effect through changes in minute ventilation and dead space. Predominantly, minute ventilation is reduced in diving due to changes in respiratory load and associated changes in respiratory control. Minute ventilation is further reduced by hyperoxic attenuation of chemosensitivity. Physiologic dead space is also increased due to elevated breathing gas density and to hyperoxia. The Haldane effect, a reduction in CO₂ solubility in blood due to hyperoxia, may contribute indirectly to hypercapnia through an increase in mixed venous PCO₂. In some individuals, low ventilatory response to hypercapnia may also contribute to carbon dioxide retention. This review outlines what is currently known about hypercapnia in diving, including its measurement, cause, mental and physical effects, and areas for future study., Competing Interests: The authors of this paper declare no conflicts of interest exist with this submission., (Copyright© Undersea and Hyperbaric Medical Society.)

Published
2017
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results