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22 results on '"Chernomordik AE"'

1. [Lactate dehydrogenase isoenzyme content of the tissue of a cancerous tumor and polyps of the large intestine].

Author

Chernomordik AE

Subjects
Adenocarcinoma diagnosis, Adenocarcinoma, Mucinous diagnosis, Biopsy, Carcinoma diagnosis, Electrophoresis, Agar Gel, Humans, Intestinal Mucosa enzymology, Isoenzymes, Clinical Enzyme Tests, Intestinal Neoplasms diagnosis, Intestinal Polyps diagnosis, Intestine, Large enzymology, L-Lactate Dehydrogenase analysis
Abstract

Electrophoretic assays of LDH-isoenzymes in agar were carried out in 599 homogenates of bioptic and resected tissue material obtained from carcinoma (174), polyps (305) and grossly normal mucosa (120). A significant considerable increase in cathode fractions of LDh4 and LDH5 matched by a decrease in LDH1, LDH2 and LDH3 levels was observed in both tumor and polyp tissue. The degree of the changes varied greatly depending on patients' age, type of tumor and size of polyp. Preoperative telegamma therapy was followed by a significant decrease in LDH5 and an increase in LDH2 levels.

Published
1982

4. [Changes in blood serum proteins and blood electrolytes in patients with rectal fistulas and hemorrhoids].

Author

Fedorov VD, Martynova TI, Ilysheva GN, Chernomordik AE, and Brandina AM

Subjects
Adult, Chlorides blood, Humans, Magnesium blood, Middle Aged, Potassium blood, Sodium blood, Blood Proteins analysis, Electrolytes blood, Hemorrhoids blood, Rectal Fistula blood
Abstract

Changes in blood serum and electrolytes were studied in 113 patients with rectal fistulas and hemorrhoid. The data obtained provided the opportunity for estimating objectively the intensity of inflammatory and destructive processes in pararectal cellular tissue.

Published
1975

5. [Changes in lactate dehydrogenase isoforms in the process of oncogenesis].

Author

Ageenko AI, Vitorgan IuE, and Chernomordik AE

Subjects
Adenoviruses, Human, Animals, Cell Transformation, Neoplastic, Cells, Cultured, Cytoplasm enzymology, Embryo, Mammalian cytology, Enzyme Activation, Fibroblasts enzymology, Humans, Intestinal Neoplasms enzymology, Intestinal Polyps enzymology, Isoenzymes, Oncogenic Viruses, Rats, Time Factors, L-Lactate Dehydrogenase metabolism, Neoplasms etiology
Abstract

Isoenzymes of lactate dehydrogenase were studied by disc-electrophoresis in polyacrylamide gel, and in the clinic--in 1% agar gel. Oncovirus A12 invasion of the culture of rat embryo fibroblasts (REF) was found to result in the increased percentage of the cathode fractions activity (LDG-4 and LD-5) and in the disappearance of LDG-1 yet during the first day of the experiment prior to hypoxia and enhanced proliferation, i. e. it is most likely to be primary. In the homogenates of cancerous tumor and large intestine polyps of man also a reliable increase of the cathode and a decrease or disappearance of the anode fractions accur. A correlation of the experimental and clinical data allowed a suggestion to be made that LDG isoenzymes changes are genetically conditioned and play an important role in the process of oncogenesis, providing conditions for the increased intensity of glycolysis and proliferation.

Published
1978

6. [Changes of the indicators of the kallikrein-kinin system in diffuse polyposis and cancer of the large intestine before and after radical operation].

Author

Pokrovskiĭ GA, Ilysheva GN, Chernomordik AE, Maksimova LV, and Nikitin AM

Subjects
Adolescent, Adult, Aged, Colonic Neoplasms surgery, Female, Humans, Intestinal Polyps surgery, Male, Middle Aged, Rectal Neoplasms surgery, Aprotinin blood, Colonic Neoplasms enzymology, Enzyme Precursors blood, Intestinal Polyps enzymology, Kallikreins blood, Rectal Neoplasms enzymology
Published
1978

8. [Water-electrolyte metabolism in nonspecific ulcerative colitis].

Author

Brandina AM, Ilysheva GN, Chernomordik AE, Levitan MKh, and Brusilovskiĭ MI

Subjects
Colitis, Ulcerative complications, Humans, Hypokalemia etiology, Hyponatremia etiology, Colitis, Ulcerative metabolism, Potassium metabolism, Sodium metabolism, Water-Electrolyte Imbalance etiology
Published
1975

12. [Pathologic mineral metabolism in patients with post-dysentery lesions of the gastrointestinal tract].

Author

Pokrovskiĭ GA, Brandina AM, Chernomordik AE, Bronshteĭn AS, and Dubinin AV

Subjects
Adolescent, Adult, Calcium blood, Constipation metabolism, Diarrhea metabolism, Female, Gastrointestinal Diseases etiology, Humans, Magnesium urine, Male, Middle Aged, Potassium blood, Potassium urine, Sodium blood, Sodium urine, Calcium metabolism, Chlorides metabolism, Dysentery, Bacillary complications, Gastrointestinal Diseases metabolism, Magnesium metabolism, Potassium metabolism, Sodium metabolism, Water-Electrolyte Balance
Published
1974

22. Materials on measles pathogenesis and vaccinal process.

Author

Sergiev PG, Shroit IG, Chelysheva KM, Smirnova EV, Kuksova MI, Shevtsova ZV, Levenshtam MA, Chernomordik AE, Kozlyuk AS, Stromova GI, Manjko TG, Yefimov EE, Shamrayeva SA, and Voskresenskaya GS

Subjects
Animals, Antibody Formation, Complement Fixation Tests, Haplorhini, Neutralization Tests, Measles Vaccine, Measles virus pathogenicity
Published
1966

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