1. Preload and flow propagation velocity: insight into patients with uremia and different left ventricular systolic function
- Author
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Shih-Kai Lin, Chun-Peng Liu, Wei-Chen Huang, Shih-Hung Hsiao, Tao Yu Lee, and Cheng Len L. Sy
- Subjects
Male ,medicine.medical_specialty ,medicine.medical_treatment ,Diastole ,Blood Pressure ,Systolic function ,Flow propagation ,Sensitivity and Specificity ,Severity of Illness Index ,Ventricular Dysfunction, Left ,Renal Dialysis ,Internal medicine ,Coronary Circulation ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Sinus rhythm ,Uremia ,Ejection fraction ,business.industry ,Reproducibility of Results ,Stroke Volume ,Middle Aged ,medicine.disease ,Preload ,Treatment Outcome ,Echocardiography ,Cardiology ,Female ,Hemodialysis ,Cardiology and Cardiovascular Medicine ,business ,Blood Flow Velocity - Abstract
Objectives The aim of this study was to investigate the changes of flow propagation velocity (FPV) after regular hemodialysis (H/D) in patient who were uremic with different baseline left ventricular (LV) functions. Methods In all, 24 patients with uremia and abnormal LV systolic function were enrolled in this study and 30 patients with uremia and normal LV systolic performance served as the control group. All patients had in sinus rhythm and underwent a comprehensive transthoracic echocardiographic examination and mitral FPV by color M-mode echocardiography before and after H/D. Results The decline in FPV before H/D was proportional to the decline in the baseline LV function, whereas FPV after H/D varied according to the LV ejection fraction. An obvious decrement of FPV for patients with normal LV systolic function was noted, but no obvious difference was seen for patients with abnormal LV systolic function. Conclusion FPV was strongly preload dependent for patients with normal LV systolic function. It was not significantly influenced by preload for patients with abnormal LV systolic function. FPV is a relatively good diastolic parameter for investigating patients with LV systolic dysfunction.
- Published
- 2005