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Three new compounds, polygalapyrone A (1), tenuiside G (2) and polygalapyrrole A (3), together with two known compounds (4–5) were isolated by silica gel, ODS and preparative HPLC from the aerial part of Polygala tenuifolia. Their structures were elucidated by spectrum analysis and compared with findings from the literature. The anti-inflammatory effects of those compounds were investigated in vitro. [ABSTRACT FROM AUTHOR]

Seven new glycosides (1–7) and seventeen known analogues (8–24) were isolated from the leaves of Datura metel L. The structures of these compounds were all elucidated by detailed spectroscopic analyses and comparison with literature values. All isolates were evaluated for cytotoxicity against Hela, MGC-803, Ishikawa cell lines and compounds 6, 7, 14–17 and 24 exhibited different degrees of antiproliferative effects. [ABSTRACT FROM AUTHOR]

A new dammarane-type triterpenoid saponin, suanzaoside A ( 1 ) along with one known analogue 3- O -[ α -L-rhamnopyranosyl(1→2)- α -L-arabinopyranosyl-]-30- O -[ β -D-glucopyranosyl-(1→2)- β -D-glucopyranosyl]-3 β ,25,30-trihydroxy-16-one-20 R ,24 R -epoxydammarane ( 2 ), were isolated from the leaves of sour jujube. The structure of these isolated compounds was elucidated by HRESIMS, 1D and 2D NMR spectroscopy, and literature comparison. In addition, the anti-inflammatory activities were further tested in LPS-induced RAW264.7 macrophage.

A new glycoside ( 1 ) along with six known analogues ( 1-7 ) were isolated from Codonopsis pilosula collected at Shanxi in China. The structure of 1 was established based on comprehensive spectroscopic data and literature comparison. The anti-inflammatory effects of isolated compounds were further investigated in LPS-induced RAW264.7 macrophage.