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Ventilation air methane (VAM) is one of the main greenhouse gas sources. Owing to the characteristics of low concentration of ventilation air methane and high moisture content, we build an experimental platform and take the oxidative combustion temperature and methane conversion rate as the research indexes, and the systematic research finds that the inhibitory effect of moisture on the oxidative combustion of ultra‐low concentration of methane (<1%) is a nonlinear polynomial law. In the meantime, we constructed OH(H2O)n+CH4 and studied its reaction potential energy surface using quantum chemical calculations, which used the most significant primitive reaction of methane combustion, OH+CH4→H2O+CH3, as the theoretical basis. We found that as moisture content increased, so did its reaction energy barrier, making the reactants more stable, strengthening the three‐body collision effect, and reducing the number of free radicals, all of which hindered the methane chain reaction. The study aimed to validate the experimental finding that moisture inhibits the oxidative combustion of ventilation air methane by examining the internal mechanism of methane oxidation. © 2024 Society of Chemical Industry and John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

Introduction: Despite the extensive neurological symptoms induced by COVID‐19 and the identification of SARS‐CoV‐2 in post‐mortem brain samples from COVID‐19 patients months after death, the precise mechanisms of SARS‐CoV‐2 invasion into the central nervous system remain unclear due to the lack of research models. Methods: We collected glioma tissue samples from glioma patients who had a recent history of COVID‐19 and examined the presence of the SARS‐CoV‐2 spike protein. Subsequently, spatial transcriptomic analyses were conducted on normal brain tissues, glioma tissues, and glioma tissues from glioma patients with recent COVID‐19 history. Additionally, single‐cell sequencing data from both glioma tissues and glioma organoids were collected and analyzed. Glioma organoids were utilized to evaluate the efficacy of potential COVID‐19 blocking agents. Results: Glioma tissues from glioma patients with recent COVID‐19 history exhibited the presence of the SARS‐CoV‐2 spike protein. Differences between glioma tissues from glioma patients who had a recent history of COVID‐19 and healthy brain tissues primarily manifested in neuronal cells. Notably, neuronal cells within glioma tissues of COVID‐19 history demonstrated heightened susceptibility to Alzheimer's disease, depression, and synaptic dysfunction, indicative of neuronal aberrations. Expressions of SARS‐CoV‐2 entry factors were confirmed in both glioma tissues and glioma organoids. Moreover, glioma organoids were susceptible to pseudo‐SARS‐CoV‐2 infection and the infections could be partly blocked by the potential COVID‐19 drugs. Conclusions: Gliomas had inherent traits that render them susceptible to SARS‐CoV‐2 infection, leading to their representability of COVID‐19 neurological symptoms. This established a biological foundation for the rationality and feasibility of utilization of glioma organoids as research and blocking drug testing model in SARS‐CoV‐2 infection within the central nervous system. [ABSTRACT FROM AUTHOR]

To effectively utilize ventilation air methane (VAM), it is proposed to pass it into the boiler of the coal‐fired power plant for mixed combustion. However, the different types of thermal coal utilized present distinct characteristics when mixed with VAM. In this paper, lignite, bituminous coal, and anthracite are selected to study the CH4 conversion rate, system ignition temperature, and NO emission characteristics of the VAM‐pulverized coal coupled system on a fluidized bed experimental platform. The experimental results show that the ignition temperatures of VAM are 748, 736, and 732 °C when the CH4 concentration is 0.25, 0.5, and 0.75%. After the addition of thermal coal, the ignition temperature decreased significantly. When the CH4 concentration is 0.25%, the ignition temperature of the lignite‐VAM system is the lowest, which is 450 °C. Anthracite has the strongest catalytic effect on CH4 combustion. When the heating rate is 5 °C /min, the reaction rate of CH4 is the fastest in the anthracite‐VAM coupled system. Under laboratory conditions, the peak NO concentration in the coal‐VAM coupled system was lignite > bituminous coal > anthracite at different CH4 concentrations, and the CH4 in VAM had a reducing action on the NO generated during mixed combustion, with a stronger reducing effect observed as the CH4 concentration increased. The results of this study can lay the foundation for the industrial application of the mixed combustion of VAM and thermal coal, and be of great significance for solving the practical problems caused by the change of boiler coal types. © 2024 Society of Chemical Industry and John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]