853 results on '"Chen, Y. Eugene"'
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2. Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis
3. Endothelial KLF11 is a novel protector against diabetic atherosclerosis
4. Annexin A1 binds PDZ and LIM domain 7 to inhibit adipogenesis and prevent obesity
5. XBP1-mediated transcriptional regulation of SLC5A1 in human epithelial cells in disease conditions
6. Unleashing PD-1: a duel of immunity in aortic aneurysm formation
7. Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target
8. ZSCAN4 interacts with PARP1 to promote DNA repair in mouse embryonic stem cells
9. 14-3-3 binding motif phosphorylation disrupts Hdac4-organized condensates to stimulate cardiac reprogramming
10. Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD
11. NAD+ rescues aging-induced blood-brain barrier damage via the CX43-PARP1 axis
12. Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis
13. Single-Molecule Spatial Transcriptomics of Human Thoracic Aortic Aneurysms Uncovers Calcification-Related CARTPT-Expressing Smooth Muscle Cells
14. A ubiquitination-mediated degradation system to target 14-3-3-binding phosphoproteins
15. Computational redesign of cytochrome P450 CYP102A1 for highly stereoselective omeprazole hydroxylation by UniDesign
16. Impact of donor blood type on outcomes after prolonged allograft ischemic times
17. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
18. Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy
19. Exosomes from adipose-derived stem cells alleviate myocardial infarction via microRNA-31/FIH1/HIF-1α pathway
20. The power of genetic diversity in genome-wide association studies of lipids
21. Hepatic danger signaling triggers TREM2 + macrophage induction and drives steatohepatitis via MS4A7-dependent inflammasome activation
22. Gene editing therapy ready for cardiovascular diseases: opportunities, challenges, and perspectives
23. Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2
24. Improving the genome assembly of rabbits with long-read sequencing
25. Suppression of Vascular Macrophage Activation by Nitro-Oleic Acid and its Implication for Abdominal Aortic Aneurysm Therapy
26. Biomimetic tubular scaffold with heparin conjugation for rapid degradation in in situ regeneration of a small diameter neoartery
27. Integration of Transformative Platforms for the Discovery of Causative Genes in Cardiovascular Diseases
28. Synthetic high-density lipoproteins delivering liver X receptor agonist prevent atherogenesis by enhancing reverse cholesterol transport
29. Human apolipoprotein A-II reduces atherosclerosis in knock-in rabbits
30. Sotagliflozin attenuates liver associated disorders in cystic fibrosis rabbits
31. SWI/SNF Complex in Vascular Smooth Muscle Cells and Its Implications in Cardiovascular Pathologies
32. Translating Cardiovascular Genomics to Clinical Practice
33. BAF60c prevents abdominal aortic aneurysm formation through epigenetic control of vascular smooth muscle cell homeostasis
34. Hypertension Enhances Advanced Atherosclerosis and Induces Cardiac Death in Watanabe Heritable Hyperlipidemic Rabbits
35. Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol
36. Hepatic danger signaling triggers TREM2+ macrophage induction and drives steatohepatitis via MS4A7-dependent inflammasome activation.
37. Epidemiologic and Genetic Associations of Erythropoietin With Blood Pressure, Hypertension, and Coronary Artery Disease
38. hiPSC Modeling of Lineage-Specific Smooth Muscle Cell Defects Caused by TGFBR1A230T Variant, and Its Therapeutic Implications for Loeys-Dietz Syndrome
39. Endothelial TFEB (Transcription Factor EB) Improves Glucose Tolerance via Upregulation of IRS (Insulin Receptor Substrate) 1 and IRS2
40. Krüppel-like factor 14, a coronary artery disease associated transcription factor, inhibits endothelial inflammation via NF-κB signaling pathway
41. Effect of Ambient Fine Particulate Matter Air Pollution and Colder Outdoor Temperatures on High-Density Lipoprotein Function
42. BAF60a Deficiency in Vascular Smooth Muscle Cells Prevents Abdominal Aortic Aneurysm by Reducing Inflammation and ECM (Extracellular Matrix) Degradation
43. Clopidogrel Resistance in a Murine Model of Diet-Induced Obesity Is Mediated by the Interleukin-1 Receptor and Overcome With DT-678
44. Perivascular Adipose Tissue Regulates Vascular Function by Targeting Vascular Smooth Muscle Cells
45. Unleashing PD-1: a duel of immunity in aortic aneurysm formation.
46. Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease
47. MiCas9 increases large size gene knock-in rates and reduces undesirable on-target and off-target indel edits
48. XBP1-mediated transcriptional regulation of SLC5A1 in human epithelial cells in disease conditions
49. Liver-specific in vivo base editing of Angptl3 via AAV delivery efficiently lowers blood lipid levels in mice
50. Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb
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