844 results on '"Chen, Y Eugene"'
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2. XBP1-mediated transcriptional regulation of SLC5A1 in human epithelial cells in disease conditions
3. Unleashing PD-1: a duel of immunity in aortic aneurysm formation
4. Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target
5. 14-3-3 binding motif phosphorylation disrupts Hdac4-organized condensates to stimulate cardiac reprogramming
6. ZSCAN4 interacts with PARP1 to promote DNA repair in mouse embryonic stem cells
7. Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD
8. Single-Molecule Spatial Transcriptomics of Human Thoracic Aortic Aneurysms Uncovers Calcification-Related CARTPT-Expressing Smooth Muscle Cells
9. NAD+ rescues aging-induced blood-brain barrier damage via the CX43-PARP1 axis
10. Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis
11. A ubiquitination-mediated degradation system to target 14-3-3-binding phosphoproteins
12. Computational redesign of cytochrome P450 CYP102A1 for highly stereoselective omeprazole hydroxylation by UniDesign
13. Impact of donor blood type on outcomes after prolonged allograft ischemic times
14. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
15. Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy
16. Exosomes from adipose-derived stem cells alleviate myocardial infarction via microRNA-31/FIH1/HIF-1α pathway
17. The power of genetic diversity in genome-wide association studies of lipids
18. Suppression of Vascular Macrophage Activation by Nitro-Oleic Acid and its Implication for Abdominal Aortic Aneurysm Therapy
19. Gene editing therapy ready for cardiovascular diseases: opportunities, challenges, and perspectives
20. Hepatic danger signaling triggers TREM2 + macrophage induction and drives steatohepatitis via MS4A7-dependent inflammasome activation
21. Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2
22. Sotagliflozin attenuates liver associated disorders in cystic fibrosis rabbits
23. SWI/SNF Complex in Vascular Smooth Muscle Cells and Its Implications in Cardiovascular Pathologies
24. Improving the genome assembly of rabbits with long-read sequencing
25. Biomimetic tubular scaffold with heparin conjugation for rapid degradation in in situ regeneration of a small diameter neoartery
26. Synthetic high-density lipoproteins delivering liver X receptor agonist prevent atherogenesis by enhancing reverse cholesterol transport
27. Human apolipoprotein A-II reduces atherosclerosis in knock-in rabbits
28. Integration of Transformative Platforms for the Discovery of Causative Genes in Cardiovascular Diseases
29. BAF60c prevents abdominal aortic aneurysm formation through epigenetic control of vascular smooth muscle cell homeostasis
30. Unleashing PD-1: a duel of immunity in aortic aneurysm formation.
31. Translating Cardiovascular Genomics to Clinical Practice
32. Epidemiologic and Genetic Associations of Erythropoietin With Blood Pressure, Hypertension, and Coronary Artery Disease
33. hiPSC Modeling of Lineage-Specific Smooth Muscle Cell Defects Caused by TGFBR1A230T Variant, and Its Therapeutic Implications for Loeys-Dietz Syndrome
34. Hypertension Enhances Advanced Atherosclerosis and Induces Cardiac Death in Watanabe Heritable Hyperlipidemic Rabbits
35. Krüppel-like factor 14, a coronary artery disease associated transcription factor, inhibits endothelial inflammation via NF-κB signaling pathway
36. Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol
37. Hepatic danger signaling triggers TREM2+ macrophage induction and drives steatohepatitis via MS4A7-dependent inflammasome activation.
38. XBP1-mediated transcriptional regulation of SLC5A1 in human epithelial cells in disease conditions
39. Endothelial TFEB (Transcription Factor EB) Improves Glucose Tolerance via Upregulation of IRS (Insulin Receptor Substrate) 1 and IRS2
40. Effect of Ambient Fine Particulate Matter Air Pollution and Colder Outdoor Temperatures on High-Density Lipoprotein Function
41. BAF60a Deficiency in Vascular Smooth Muscle Cells Prevents Abdominal Aortic Aneurysm by Reducing Inflammation and ECM (Extracellular Matrix) Degradation
42. Clopidogrel Resistance in a Murine Model of Diet-Induced Obesity Is Mediated by the Interleukin-1 Receptor and Overcome With DT-678
43. Perivascular Adipose Tissue Regulates Vascular Function by Targeting Vascular Smooth Muscle Cells
44. Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease
45. MiCas9 increases large size gene knock-in rates and reduces undesirable on-target and off-target indel edits
46. Liver-specific in vivo base editing of Angptl3 via AAV delivery efficiently lowers blood lipid levels in mice
47. Abstract 684: Hepatic Oxalate Overproduction As A Driver And Therapeutic Target In NASH And Atherosclerosis
48. DT-109 ameliorates nonalcoholic steatohepatitis in nonhuman primates
49. Abstract 124: Synthetic High-density Lipoprotein Attenuates Abdominal Aortic Aneurysm Formation Via Restoring Vascular Smooth Muscle Cell Mitochondrial Function
50. Abstract 584: Myeloid Kruppel-like Factor 14 Mediates Sexual Dimorphism Of Abdominal Aortic Aneurysm Via Estrogen Receptor β
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