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Comprehensive Summary: Many sandwich‐type lanthanide complexes show extremely high energy barriers (Ueff) for the reversal of magnetization and high blocking temperatures, being the star molecules in the research area of single‐molecule magnets. Herein, the preparation, structural determination, and magnetic property studies of two ansa‐bridged Er‐COT (COT = cyclooctatetraenyl dianion) complexes [KDME2][Er((η8‐COT‐SiMe2)2O)] (1) and [KDME2][Er((η8‐COT‐SiiPr2)2O)]K[Er((η8‐COT‐SiiPr2)2O)] (2) were reported. The Er(III) ions in both complexes are sandwiched by two COT rings which are ansa‐bridged by a [Si‐O‐Si] group. Magnetic studies reveal both complexes display slow magnetic relaxations with comparable energy barriers (228(5) K for 1, and 196(4) K for 2) and blocking temperatures (10.5 K for both complexes). The difference in the relaxation times (τ) for the two complexes was studied in details: different molecular vibrations induced by the substituents are the main reason for τ for 1 being about 10 times longer than for 2 at the same temperature above 10 K, while the quantum tunnelling of magnetization relaxation time (τQTM) for 2 is about 10 times longer than for 1 below 8 K, probably owing to the different dipolar interactions. Further rearrangement of molecular network with such ansa‐bridged SMMs is promising to design molecular magnetic materials with enhanced properties or new properties. [ABSTRACT FROM AUTHOR]

Comprehensive Summary: Many sandwich‐type lanthanide complexes show extremely high energy barriers (Ueff) for the reversal of magnetization and high blocking temperatures, being the star molecules in the research area of single‐molecule magnets. Herein, the preparation, structural determination, and magnetic property studies of two ansa‐bridged Er‐COT (COT = cyclooctatetraenyl dianion) complexes [KDME2][Er((η8‐COT‐SiMe2)2O)] (1) and [KDME2][Er((η8‐COT‐SiiPr2)2O)]K[Er((η8‐COT‐SiiPr2)2O)] (2) were reported. The Er(III) ions in both complexes are sandwiched by two COT rings which are ansa‐bridged by a [Si‐O‐Si] group. Magnetic studies reveal both complexes display slow magnetic relaxations with comparable energy barriers (228(5) K for 1, and 196(4) K for 2) and blocking temperatures (10.5 K for both complexes). The difference in the relaxation times (τ) for the two complexes was studied in details: different molecular vibrations induced by the substituents are the main reason for τ for 1 being about 10 times longer than for 2 at the same temperature above 10 K, while the quantum tunnelling of magnetization relaxation time (τQTM) for 2 is about 10 times longer than for 1 below 8 K, probably owing to the different dipolar interactions. Further rearrangement of molecular network with such ansa‐bridged SMMs is promising to design molecular magnetic materials with enhanced properties or new properties. [ABSTRACT FROM AUTHOR]

Objectives: To study an uncommon life-threatening disease, spontaneous retroperitoneal and perirenal hemorrhage. Case descriptions: A 69-year-old male presented with pain in the left waist and back of 1 month duration. The renal abscess was suspected by magnetic resonance imaging before operation. The perirenal hematoma was cleaned by operation. In another case, the patient had a functional solitary left kidney compressed by a huge retroperitoneal mass and uropenia appeared. Results: The first patient died of adult respiratory distress syndrome after surgery. The second patient died of cardiac insufficiency and pulmonary embolism on the second day after evacuation of retroperitoneal hematoma. Conclusion: Conservative surgery, such as selective arterial embolization, is a reasonable approach in patients with chronic spontaneous retroperitoneal and perirenal space hemorrhage and with poor general condition. We strongly recommend drainage or interventional therapy, but not a major surgery, in patients with poor condition. [ABSTRACT FROM AUTHOR]

A new single-molecule magnet (SMM) complex [K(18-crown-6)][(COT)Er(µ-Cl) 3 Er(COT)] (Er 2 Cl 3 , COT = cyclooctatetraenide dianion) is obtained by the reaction of [(COT)Er(µ-Cl)(THF)] 2 (Er 2 Cl 2 , THF = tetrahydrofuran) with an equivalent of KCl in the presence of 18-crown-6. The two COT-Er units in the newly formed complex are triply bridged by µ-Cl ligands, leading to the "head-to-tail" alignment of the magnetic easy axes distinctly different from the "staggered" arrangement in the precursor complex. This structural transformation has led to significantly enhanced intramolecular dipolar interactions and a reduced transverse component of the crystal fields, increasing the energy barrier from 150(8) K for Er 2 Cl 2 to 264(4) K for Er 2 Cl 3 and extending its magnetic relaxation time at 2 K by 2500 times with respect to Er 2 Cl 2 . More importantly, the blocking temperature increased from lower than 2 K for Er 2 Cl 2 to 8 K for Er 2 Cl 3 , and the magnetic hysteresis loops at 2 K changed from butterfly-shaped for Er 2 Cl 2 to open hysteresis loop with coercive force of 7 kOe for Er 2 Cl 3 . These results suggest that the properties of SMMs can be effectively tuned and improved by rationally arranging magnetic spins via molecular engineering., (© 2024 The Author(s). Advanced Science published by Wiley‐VCH GmbH.)

Objective: In recent years, Acinetobacter baumannii has been appearing in hospitals with high drug resistance and strong vitality, which brings many difficulties to clinical treatment. In this study, 255 strains of A. baumannii were isolated from Youjiang Medical University for Nationalities Affiliated Hospital clinical samples and found to be highly resistant to carbapenems. The drug resistance, biofilm-forming ability, and carbapenase gene distribution of 145 carbapenem-resistant A. baumannii (CRAB) strains were analyzed statistically., Methods: The clinically isolated strains were detected using Vitek mass spectrometry and Vitek2-compact for bacterial identification and susceptibility testing, respectively. The biofilms of clinical isolates were quantitatively detected by microplate crystal violet staining, and qualitatively observed by confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM). And the common carbapenemase genes were detected by polymerase chain reaction (PCR)., Results: The 255 clinical isolates from the Youjiang District of western Guangxi Province had a high resistance rate to carbapenems antibiotics. The main specimens were from the intensive care unit (49%), and the most important specimens were sputum specimens (80%). All 145 strains of CRAB produced different degrees of biofilm, and six carbapenenase genes were detected. We found that there were significant differences in biofilm formation between resistant and sensitive strains of tobramycin, levofloxacin, ciprofloxacin, tigecycline, and doxycycline ( P <0.05). The distribution of bla OXA-23 and bla OXA51 genes was significantly different from CRAB biofilm formation ( P <0.05). In addition, AmpC , bla OXA-23 , bla OXA-51 , and TEM genes were more distributed in antibiotic-resistant strains., Conclusion: The clinical strains have a high resistance rate to carbapenems, and the CRAB with bla OXA-51 and bla OXA-23 genes has a high resistance to antibiotics and a strong biofilm., Competing Interests: None., (IJMEG Copyright © 2024.)

Objective: To investigate the effects of visualized precision electrophysiological diagnosis and transcutaneous low-frequency electrical stimulation (TES) on hypoxia-induced ED in high-altitude areas., Methods: This study included 152 ED patients from high-altitude hypoxic areas treated by TES based on the parameters obtained from visualized precision electrophysiological diagnosis. We followed up the patients for 1 to 3 months and compared their IIEF-5 scores, nocturnal penile tumescence and rigidity (NPTR) and infrared thermal metabolic technology (TMT)-based temperature of the whole body and diseased parts before and after treatment., Results: All the patients successfully completed 1 to 3 courses of TES. There were no statistically significant differences in the IIEF-5 scores (P<0.05) and penile tip optimal erection rigidity and duration (P<0.01) of the patients before and after treatment. TMT images indicated a temperature change of >1.5 ℃ in the penis and bilateral inguinal regions after treatment, suggesting the effectiveness of electrical stimulation. No recurrence was observed during the follow-up., Conclusion: TES based on the parameters obtained from visualized precision electrophysiological diagnosis has a definite effect on hypoxia-induced ED by enhancing oxygen supply to the penile corpus cavernosum and improving its function and structure.

An anoxic membrane bioreactor-microalgae membrane reactor coupling system (anoxic MBR-MMR) was used to deal with mariculture wastewater. Pre-anoxic MBR was used for the degradation of organic matter, NO 3 - -N and NO 2 - -N, and the released NH 4 + -N entered MMR for microalgae growth and was removed. Meanwhile, the treatment efficiency and the microalgae recovery were studied, and the membrane fouling behavior was investigated. After running for 91 days, the removal rates of the system toward NO 3 - -N and NH 4 + -N were stable at above 90.0% and 88.0%, respectively. Furthermore, the average removal rates of PO 4 3- -P and TOC were 49.4% and 84.7%, respectively. Under the condition that the microalgae were harvested continuously, the biomass can be stably operated at an average concentration of 9×10 7 cells·mL -1 and good removal efficiency and resource utilization could be achieved. Through infrared spectrum and three-dimensional fluorescence spectrum analysis, the main substances causing membrane fouling in MMR were tryptophan proteins and humic acids. The membrane fouling in MMR was lighter than that in anoxic MBR.

Objective: To explore the applicability of RigiScan monitoring data in the diagnosis of ED in the plateau area and evaluation of clinical therapeutic effects., Methods: This study included 586 outpatients and inpatients with ED, aged 18－48 (mean 24.6) years, all confirmed according to the scores on the 5-item version of the International Index of Erectile Function (IIEF-5) and subjective description and treated in Xining First People's Hospital. We performed audiovisual sexual stimulation (AVSS) and nocturnal penile tumescence and rigidity (NPTR) tests by RigiScan monitoring and hierarchical diagnosis of those with abnormal AVSS and NPTR findings. After 1 to 6 months of individualized treatment with PDE5i drugs and a month of drug withdrawal and psychological intervention, we repeated the AVSS test and analyzed the data obtained in comparison with the IIEF-5 scores and subjective description of the patients before and after treatment., Results: Of the 586 patients, 3 were found normal and 583 abnormal (without effective erection, i.e., penile tip rigidity <60% and <10 min) in the AVSS test, while the repeated NPTR test showed 57 normal (with effective erection, i.e., penile tip rigidity ≥60% and ≥10 min). A total of 116 patients gave up the NPTR test. Altogether 410 of the cases were found without effective erection in the NPTR test before treatment, 207 (50.5%) with mild ED, 176 (42.9%) with moderate ED and 27 (6.6%) with severe ED. Of the 410 patients, based on the result of the repeated AVSS test after treatment, 255 (62.2%, including 172 cases ［42.0%］ of mild ED and 83 cases ［20.2%］ of moderate ED) were shown with effective erection, 124 (30.2%, including 35 cases ［8.5%］ of mild ED, 77 cases ［18.8%］ of moderate ED and 12 cases ［2.9%］ of severe ED) were significantly improved (P < 0.05), and the other 31 (7.6%, including 16 cases ［3.9%］ of moderate ED and 15 cases ［3.7%］ of severe ED) remained unchanged. The IIEF -5 score was remarkably increased after treatment compared with the baseline (18.62 ± 2.96 vs 11.62 ± 3.64, P < 0.05), and the erectile function and erection-control ability of the patients, according to their subjective description, were markedly improved after treatment., Conclusions: RigiScan with AVSS and NPTR tests can objectively assess the severity of ED, screen its causes and evaluate the effects of medication and psychological intervention for patients in plateau areas.

In order to treat mariculture wastewater, the pollutant removal performance and membrane fouling characteristics of a microalgae membrane reactor were investigated using Platymonas helgolandica tsingtaoensis . After 60 days of operation, the total nitrogen (TN) and total phosphorus (TP) removal efficiency of the reactor were 73.6% and 77.9%, respectively, and the removal rates of TN and TP reached 15 g·(m 3 ·d) -1 and 2.8 g·(m 3 ·d) -1 . The microalgae in the reactor could be enriched rapidly, with a maximum growth rate of 53.3 mg·(L·d) -1 and a maximum biomass of 1.4 g·L -1 . The microalgae in the reactor were harvested on day 18 and day 36; harvesting did not affect the nitrogen and phosphorus removal efficiency of the reactor. To some extent, the membrane fouling phenomenon was alleviated. The increase in the microalgae biomass would significantly increase the pollutant content of the membrane. The three-dimensional excitation-emission matrix (EEM) spectra results confirmed that tryptophan-like substances and aromatic proteins had a significant effect on membrane fouling.

Objective: To investigate the relationship between renal clear cell carcinoma and type 2 diabetes mellitus (DM)., Methods: Two hundreds and sixty-four patients with renal clear cell carcinoma and four hundred controls who suffered from non-urinary system, non-neoplastic or non-hormone-related disorders, were enrolled from January 2008 to December 2012. The incidence of diabetes between the 2 groups and the relationship between renal clear cell carcinoma and duration of diabetes were compared, moreover, renal clear cell carcinoma patients with DM were compared with patients without DM for their clinical features, laboratory examinations and histological characteristics., Results: The comparison of renal clear cell carcinoma group and control group: the incidence of DM in the two groups were 19.7% and 12.8% respectively, and the difference was significant (χ(2) = 5.86, P < 0.05, OR = 1.68). In the renal clear cell carcinoma group, the proportion of patients with DM diagnosed within 2-4 years was 4.92%, which were significant higher than those in the control group 1.70% (χ(2) = 5.49, P < 0.05, OR = 2.91). And men with diabetes had high occurrence risk 86% of renal clear cell carcinoma (OR = 1.86, 95%CI: 1.09-3.15). The comparison of diabetes patients subgroup and non-diabetic patients subgroup in renal clear cell carcinoma group: in respect of clinical features, greatest tumor diameter in the two subgroups were (4.9 ± 2.3) cm and (4.2 ± 2.1) cm respectively, and the difference was significant (t = 1.96, P < 0.05). However, there was no significant difference in terms of age, gender and cancer location between the two subgroups (P > 0.05). In respect of laboratory examinations, serum creatinine in the two subgroups were (72 ± 20) µmol/L and (65 ± 17) µmol/L, and the difference was significant (t = 2.34, P < 0.05); serum urea nitrogen in the 2 subgroups were (7.1 ± 2.1) mmol/L and (6.0 ± 1.5) mmol/L respectively, and the difference was significant too (t = 1.47, P < 0.05). In respect of histological characteristics, the proportion of well differentiated clear cell carcinoma were 80.8% and 81.1% respectively, and the difference was significant (χ(2) = 4.23, P < 0.05). The proportion of stage II were 25.0% and 27.8% respectively and the difference was significant (χ(2) = 4.08, P < 0.05)., Conclusions: DM is closely related with renal clear cell carcinoma and DM may be a possible risk factor for the tumor. And for elderly patients with diabetes who appear waist discomfort or hematuria, a careful examination of kidney is important to make early diagnosis, give timely treatment and improve survival prognosis.