Search

Your search keyword '"Chen, Jieqing"' showing total 160 results
Start Over Author "Chen, Jieqing"
160 results on '"Chen, Jieqing"'

4. Association between ICU quality and in-hospital mortality of V-V ECMO-supported patients—the ECMO quality improvement action (EQIA) study: a national cohort study in China from 2017 to 2019

Author

Cheng, Wei, Chen, Jieqing, Ma, Xudong, Sun, Jialu, Gao, Sifa, Wang, Ye, Su, Longxiang, Wang, Lu, Du, Wei, He, Huaiwu, Chen, Yujie, Li, Zunzhu, Li, Qi, Sun, Jianhua, Luo, Hongbo, Liu, Jinbang, Shan, Guangliang, Du, Bing, Guo, Yanhong, Liu, Dawei, Yin, Chang, and Zhou, Xiang

Published
2024
Full Text
View/download PDF

10. Adaptive Cooperative Game Penetration Guidance for Multiple Hypersonic Vehicles With Performance Constraints

Author

Chen, Jieqing, Sun, Ruisheng, Lu, Yu, and Zhao, Ri

Abstract

The rapid development of the antimissile weapon systems brings new challenges to the cooperative penetration strategy solution and the guidance law design for hypersonic vehicles (HVs). This article studies the cooperative game penetration guidance problem for multiple HVs with performance constraints. A cooperative differential game model for HVs is proposed wherein a cooperative gain is incorporated to assign maneuvering ratios in different cooperative missions and the ground target is considered as a member of the interceptor swarm to be able to attack the target after penetration. Then, an improved prescribed performance adaptive dynamic programming (ADP) algorithm is developed to seek the Nash equilibrium guidance solution quickly and accurately. In order to ensure the steady-state and transient approximation performance of neural networks strictly, a prescribed performance function is introduced into the weight updating law design. Using the developed strategies, it is proven that the desired approximation performance in ADP can be achieved. Finally, a comparative simulation with a two-on-three game is conducted to verify the effectiveness of the proposed method.

Published
2024
Full Text
View/download PDF

18. Supplementary Figure 1 from Overcoming Trastuzumab Resistance in Breast Cancer by Targeting Dysregulated Glucose Metabolism

Author

Zhao, Yuhua, primary, Liu, Hao, primary, Liu, Zixing, primary, Ding, Yan, primary, LeDoux, Susan P., primary, Wilson, Glenn L., primary, Voellmy, Richard, primary, Lin, Yifeng, primary, Lin, Wensheng, primary, Nahta, Rita, primary, Liu, Bolin, primary, Fodstad, Oystein, primary, Chen, Jieqing, primary, Wu, Yun, primary, Price, Janet E., primary, and Tan, Ming, primary

Published
2023
Full Text
View/download PDF

19. Supplementary Figure Legends 1-3 from Overcoming Trastuzumab Resistance in Breast Cancer by Targeting Dysregulated Glucose Metabolism

Author

Zhao, Yuhua, primary, Liu, Hao, primary, Liu, Zixing, primary, Ding, Yan, primary, LeDoux, Susan P., primary, Wilson, Glenn L., primary, Voellmy, Richard, primary, Lin, Yifeng, primary, Lin, Wensheng, primary, Nahta, Rita, primary, Liu, Bolin, primary, Fodstad, Oystein, primary, Chen, Jieqing, primary, Wu, Yun, primary, Price, Janet E., primary, and Tan, Ming, primary

Published
2023
Full Text
View/download PDF

20. Data from Overcoming Trastuzumab Resistance in Breast Cancer by Targeting Dysregulated Glucose Metabolism

Author

Zhao, Yuhua, primary, Liu, Hao, primary, Liu, Zixing, primary, Ding, Yan, primary, LeDoux, Susan P., primary, Wilson, Glenn L., primary, Voellmy, Richard, primary, Lin, Yifeng, primary, Lin, Wensheng, primary, Nahta, Rita, primary, Liu, Bolin, primary, Fodstad, Oystein, primary, Chen, Jieqing, primary, Wu, Yun, primary, Price, Janet E., primary, and Tan, Ming, primary

Published
2023
Full Text
View/download PDF

22. Supplementary Figure 2 from Overcoming Trastuzumab Resistance in Breast Cancer by Targeting Dysregulated Glucose Metabolism

Author

Zhao, Yuhua, primary, Liu, Hao, primary, Liu, Zixing, primary, Ding, Yan, primary, LeDoux, Susan P., primary, Wilson, Glenn L., primary, Voellmy, Richard, primary, Lin, Yifeng, primary, Lin, Wensheng, primary, Nahta, Rita, primary, Liu, Bolin, primary, Fodstad, Oystein, primary, Chen, Jieqing, primary, Wu, Yun, primary, Price, Janet E., primary, and Tan, Ming, primary

Published
2023
Full Text
View/download PDF

25. Supplementary Figure 3 from Overcoming Trastuzumab Resistance in Breast Cancer by Targeting Dysregulated Glucose Metabolism

Author

Zhao, Yuhua, primary, Liu, Hao, primary, Liu, Zixing, primary, Ding, Yan, primary, LeDoux, Susan P., primary, Wilson, Glenn L., primary, Voellmy, Richard, primary, Lin, Yifeng, primary, Lin, Wensheng, primary, Nahta, Rita, primary, Liu, Bolin, primary, Fodstad, Oystein, primary, Chen, Jieqing, primary, Wu, Yun, primary, Price, Janet E., primary, and Tan, Ming, primary

Published
2023
Full Text
View/download PDF

27. RNA Sequencing (RNA-Seq) Analysis Reveals Liver Lipid Metabolism Divergent Adaptive Response to Low- and High-Salinity Stress in Spotted Scat (Scatophagus argus).

Author

Chen, Jieqing, Cai, Bosheng, Tian, Changxu, Jiang, Dongneng, Shi, Hongjuan, Huang, Yang, Zhu, Chunhua, Li, Guangli, and Deng, Siping

Subjects
*LIPID metabolism, *RNA sequencing, *LIVER analysis, *UNSATURATED fatty acids, *PEROXISOME proliferator-activated receptors, *FISH adaptation, *METABOLISM, *OSMOREGULATION
Abstract

Simple Summary: The liver transcriptome was analyzed after 22 d culture with different salinity water using RNA sequencing (RNA-seq) in spotted scat (Scatophagus argus). The genes involved in lipid metabolism were differentially down- or up-regulated in low (5 ppt)- and high (35 ppt)-salinity-rated fish in comparison with the control (25 ppt) group. The difference in liver lipid metabolism is important to adapt to low- and high-salinity stress in spotted scat, which has an important value for understanding the molecular basis of salinity adaptation in euryhaline fish. Spotted scat (Scatophagus argus) can tolerate a wide range of salinity fluctuations. It is a good model for studying environmental salinity adaptation. Lipid metabolism plays an important role in salinity adaptation in fish. To elucidate the mechanism of lipid metabolism in the osmoregulation, the liver transcriptome was analyzed after 22 d culture with a salinity of 5 ppt (Low-salinity group: LS), 25 ppt (Control group: Ctrl), and 35 ppt (High-salinity group: HS) water by using RNA sequencing (RNA-seq) in spotted scat. RNA-seq analysis showed that 1276 and 2768 differentially expressed genes (DEGs) were identified in the LS vs. Ctrl and HS vs. Ctrl, respectively. Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that the pathways of steroid hormone biosynthesis, steroid biosynthesis, glycerophospholipid metabolism, glycerolipid metabolism, and lipid metabolism were significantly enriched in the LS vs. Ctrl. The genes of steroid biosynthesis (sqle, dhcr7, and cyp51a1), steroid hormone biosynthesis (ugt2a1, ugt2a2, ugt2b20, and ugt2b31), and glycerophospholipid metabolism (cept1, pla2g4a, and ptdss2) were significantly down-regulated in the LS vs. Ctrl. The pathways related to lipid metabolisms, such as fatty acid metabolism, fatty acid biosynthesis, peroxisome proliferator-activated receptor (PPAR) signaling pathway, adipocytokine signaling pathway, fatty acid degradation, and unsaturated fatty acid biosynthesis, were significantly enriched in the HS vs. Ctrl. The genes of unsaturated fatty acid biosynthesis (scd1, hacd3, fads2, pecr, and elovl1) and adipocytokine signaling pathway (g6pc1, socs1, socs3, adipor2, pck1, and pparα) were significantly up-regulated in the HS vs. Ctrl. These results suggest that the difference in liver lipid metabolism is important to adapt to low- and high-salinity stress in spotted scat, which clarifies the molecular regulatory mechanisms of salinity adaptation in euryhaline fish. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

38. CRISPR-Cas13-Mediated Knockdown of lncRNA-GACAT3 Inhibited Cell Proliferation and Motility, and Induced Apoptosis by Increasing p21, Bax, and E-Cadherin Expression in Bladder Cancer

Author

Zhang, Zhongfu, primary, Chen, Jieqing, additional, Zhu, Zhongshuang, additional, Zhu, Zhongqing, additional, Liao, Xinhui, additional, Wu, Jianting, additional, Cheng, Jianli, additional, Zhang, Xintao, additional, Mei, Hongbing, additional, and Yang, Guosheng, additional

Published
2021
Full Text
View/download PDF

44. rs11614913 polymorphism in miRNA-196a2 and cancer risk: an updated meta-analysis

Author

Liu,Yuhan, He,Anbang, Liu,Baoer, Zhong,Yucheng, Liao,Xinhui, Yang,Jiangeng, Chen,Jieqing, Wu,Jianting, and Mei,Hongbing

Subjects
OncoTargets and Therapy
Abstract

Yuhan Liu,1,* Anbang He,1,2,* Baoer Liu,1 Yucheng Zhong,1 Xinhui Liao,1 Jiangeng Yang,1 Jieqing Chen,1 Jianting Wu,1 Hongbing Mei1 1Department of Urology, Shenzhen Second People’s Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China; 2Department of Urology, Peking University First Hospital, The Institute of Urology, Peking University, National Urological Cancer Centre, Beijing, China *These authors contributed equally to this work Abstract: Several epidemiological studies have reported that polymorphisms in microRNA-196a2 (miR-196a2) were associated with various cancers. However, the results remained unverified and were inconsistent in different cancers. Therefore, we carried out an updated meta-analysis to elaborate the effects of rs11614913 polymorphism on cancer susceptibility. A total of 84 articles with 35,802 cases and 41,541 controls were included to evaluate the association between the miR-196a2 rs11614913 and cancer risk by pooled odds ratios (ORs) and 95% confidence intervals (CIs). The results showed that miR-196a2 rs11614913 polymorphism is associated with cancer susceptibility, especially in lung cancer (homozygote comparison, OR =0.840, 95% CI=0.734–0.961; recessive model, OR =0.858, 95% CI =0.771–0.955), hepatocellular carcinoma (allelic contrast, OR=0.894, 95% CI=0.800–0.998; homozygote comparison, OR=0.900, 95% CI =0.813–0.997; recessive model, OR=0.800, 95% CI=0.678–0.944), and head and neck cancer (allelic contrast, OR=1.076, 95% CI=1.006–1.152; homozygote comparison, OR=1.214, 95% CI=1.043–1.413). In addition, significant association was found among Asian populations (allele model, OR=0.847, 95% CI=0.899–0.997, P=0.038; homozygote model, OR=0.878, 95% CI=0.788–0.977,P=0.017; recessive model, OR=0.895, 95% CI=0.824–0.972,P=0.008) but not in Caucasians. The updated meta-analysis confirmed the previous results that miR-196a2 rs11614913 polymorphism may serve as a risk factor for patients with cancers. Keywords: miR-196a2, polymorphisms, cancer risk, meta-analysis

Published
2018

45. Efficacy and safety of tenofovir disoproxil fumarate in preventing vertical transmission of hepatitis B in pregnancies with high viral load

Author

Chen Jieqing, Huang Feilong, Liu Jiaqi, Cheng Xueyuan, Wen-Bo Wang, Su Rukui, Huang Zhong, Jun-Ze Chen, and Liao Zuowei

Subjects
Adult, Male, Hepatitis B virus, medicine.medical_specialty, Science, medicine.disease_cause, Placebo, Antiviral Agents, Article, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, Pregnancy, law, Internal medicine, Outcome Assessment, Health Care, Odds Ratio, medicine, Humans, Hepatitis B Vaccines, 030212 general & internal medicine, Tenofovir, Adverse effect, Multidisciplinary, business.industry, Infant, Newborn, Infant, Odds ratio, Viral Load, Hepatitis B, medicine.disease, Infectious Disease Transmission, Vertical, Immunology, Medicine, Female, 030211 gastroenterology & hepatology, business, Publication Bias, Viral load
Abstract

This study was a meta-analysis of the literature on the efficacy and safety of tenofovir disoproxil fumarate (TDF) in preventing vertical transmission of hepatitis B in pregnancies with high viral load. Four observational studies and one randomized controlled trial involving 585 pregnant women and 595 newborns were included in the meta-analysis. TDF was more effective than the placebo in reducing vertical transmission in HBeAg-positive chronic hepatitis B (CHB) pregnancies with high serum HBV-DNA levels (OR = 0.21, 95% CI = 0.07–0.61) at 4–12 months, infant HBV DNA seropositivity at delivery (OR = 0.16, 95% CI = 0.07–0.37), and a severe flair in maternal alanine aminotransferase (ALT) levels (OR = 0.43, 95% CI = 0.19–0.95) during pregnancy. In addition, TDF showed more improvement in HBV DNA suppression at delivery (OR = 254.46, 95% CI = 28.39–2280.79). No significant differences were found in HBeAg seroconversion or ALT normalization; or in rates of cesarean section, emergent cesarean section, postpartum hemorrhage, prematurity, congenital malformations, or infant death. However, TDF induced more drug-related adverse events (OR = 2.33, 95% CI = 1.39–3.89) and elevated creatine kinase (CK) (OR = 9.56, 95% CI = 1.17–78.09) than in controls. The available evidence suggests that TDF is effective and safe in preventing vertical transmission of hepatitis B in pregnancies exhibiting a high viral load.

Published
2017

48. Evaluation of Blood-Based Antibody Rapid Testing for HIV Early Therapy: A Meta-Analysis of the Evidence

Author

Huang, Xiaojie, primary, Liu, Xinchao, additional, Chen, Jieqing, additional, Bao, Yugang, additional, Hou, Jianhua, additional, Lu, Xiaofan, additional, Xia, Wei, additional, Xia, Huan, additional, Song, Aixin, additional, Liu, Zhiying, additional, Su, Bin, additional, Chen, Hui, additional, Chen, Yaokai, additional, and Wu, Hao, additional

Published
2018
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results