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This paper takes Yangronghade Village, an ethnic village of northwest Sichuan Province, as a case study to analyze tourists perceptions of the tourism image of ethnic villages. Python is used for the analysis of relevant web texts from tourism websites through word frequency analysis, semantic network analysis, and ROST-CM6 is sused for sentiment analysis, which finds that tourists generally hold a positive perception of Yangronghade Village, which is reflected in four key aspects: landscape, activity experiences, cultural characteristics, and service quality/infrastructure. The positive perceptions are largely driven by the village's natural ecological environment and ethnic cultural customs. Overall, tourists' emotional attitudes towards the village are predominantly favorable, with positive perceptions outweighing negative ones. However, some negative sentiments were expressed regarding tourism experiences, the atmosphere, facilities and services, and transportation routes. Based on the network text analysis and the village's current development situation, it is recommended that the village establish a clear brand identity, develop unique tourism products, improve infrastructure and service quality, and enhance media promotion to strength - en the cultural atmosphere. [ABSTRACT FROM AUTHOR]

Lipids in cumulus–oocyte complexes are important actors in molecular signalling pathways and are influenced by maturation conditions. Acetyl‐L‐carnitine (ALC) is a carrier involved in fatty acid transport and is a promoter of β‐oxidation. Although the embryonic development potential of oocytes can be improved when ALC is added to the maturation medium, the effects of ALC on the lipid content and composition of oocytes and cumulus cells remain unknown. In this study, the effect of ALC supplementation on the lipid profiles of buffalo oocytes and cumulus cells after in vitro maturation was evaluated using positive‐ion matrix‐assisted laser desorption ionisation time‐of‐flight mass spectrometry (MALDI‐TOF MS). Orthogonal projections to latent structures discriminant analysis was used to analyse the data. The lipid profiles of oocytes and cumulus cells differed following ALC treatment. Four lipids were significantly different in oocytes and eight in granulosa cells. ALC treatment significantly reduced the cellular content of these lipids, with the exception of phosphatidylcholine [PC(36:3) + H] + in oocytes and triacylglycerol [TAG(58:8) + NH4] + in granulosa cells. Further staining experiments confirmed that ALC treatment reduced the total lipid content in oocytes. Therefore, ALC treatment alters lipid metabolism in oocytes and cumulus cells during their maturation and accelerates lipid metabolism in oocytes. The findings of this study demonstrate that ALC enhances the rate of oocyte maturation by altering lipid metabolism in oocytes, providing both a clear direction for further research into regulatory mechanisms as well as a foundation for further improving oocyte maturation rates. [ABSTRACT FROM AUTHOR]

Objectives: The purpose of this study was to provide a comprehensive overview of the prevalence, measurement tools, influencing factors, and interventions for fear of falling (FOF) in stroke survivors. Methods: A PRISMA-guided systematic literature review was conducted. PubMed, EMBASE, Cochrane, and Web of Science were systematically searched. The search time was up to February 2023. All observational and experimental studies investigating FOF in stroke patients were included. The assessment tool of the Joanna Briggs Institute was used to assess the quality of the included studies and the risk of bias assessment. (PROSPERO: CRD42023412522). Result: A total of 25 observational studies and 10 experimental studies were included. The overall quality of the included studies was "low" to "good." The most common tool used to measure the FOF was the Falls Efficacy Scale-International (FES-I). The prevalence of FOF was 42%- 93.8%. Stroke survivors with physical impairments have the highest prevalence of FOF. The main risk factors for the development of FOF in stroke survivors were female gender, use of assistive devices, balance, limb dysfunction, and functional mobility. The combination of cognitive behavioral and exercise interventions is the most effective strategy. Conclusions: This review suggests that the prevalence of FOF in stroke survivors is high and that understanding the factors associated with FOF in stroke patients can help develop multifactorial prevention strategies to reduce FOF and improve quality of life. In addition, a uniform FOF measurement tool should be used to better assess the effectiveness of interventions for stroke survivors. Ethics approval: PROSPERO registration (CRD42023412522) [ABSTRACT FROM AUTHOR]

In dimorphic fungi, the yeast‐to‐filament transition critical for cell survival under nutrient starvation is controlled by both activators and repressors. However, very few filamentation repressors are known. Here we report that, in the dimorphic yeast Yarrowia lipolytica, the conserved transcription factor YlNrg1 plays a minor role whereas Fts1, a newly identified Zn(II)2Cys6 zinc cluster transcription factor, plays a key role in filamentation repression. FTS1 deletion caused hyperfilamentation whereas Fts1 overexpression drastically reduced filamentation. The expression of FTS1 is downregulated substantially during the yeast‐to‐filament transition. Transcriptome sequencing revealed that Fts1 represses 401 genes, including the filamentation‐activating transcription factor genes MHY1, YlAZF1, and YlWOR4 and key cell wall protein genes. Tup1‐Ssn6, a general transcriptional corepressor, is involved in the repression of many cellular functions in fungi. We show that both YlTup1 and YlSsn6 strongly repress filamentation in Y. lipolytica. YlTup1 and YlSsn6 together repress 1383 genes, including a large number of transcription factor and cell wall protein genes, which overlap substantially with Fts1‐repressed genes. Fts1 interacts with both YlTup1 and YlSsn6, and LexA‐Fts1 fusion represses a lexAop‐promoter‐lacZ reporter in a Tup1‐Ssn6‐dependent manner. Our findings suggest that Fts1 functions as a transcriptional repressor, directing the repression of target genes through the Tup1‐Ssn6 corepressor. [ABSTRACT FROM AUTHOR]

Purpose: To evaluate the blood glucose and renal function, determine the prevalence of hyperglycemia/diabetes mellitus (DM) and renal disease (nephropathy), and investigate the association between hyperglycemia/DM and renal disease in patients with viral hepatitis (VH). Patients and Methods: A total of 491 subjects were included in the study. Patients with VH were further divided into the hepatitis B virus (HBV) infection, hepatitis C virus (HCV) infection, and HBV-HCV co-infection subgroups. Fasting blood glucose, glycated hemoglobin (HbA1c), glycated albumin (GA), glutamic oxaloacetic transaminase (GOT), creatinine (Cr), and cystatin C (Cys C) levels were measured. Urine microalbumin levels were also assessed. Formulas for estimated average glucose calculated using glycated albumin(eAG(GA)), estimated average glucose calculated using HbA1c (eAG(HbA1c)), and estimated glomerular filtration rate calculated using cystatin C (eGFRcys) were used to evaluate the average glucose and renal function. Results: The prevalence of hyperglycemia/DM and renal disease was significantly higher in the VH group, especially in the HCV subgroup. The prevalence of renal disease was significantly higher in patients with VH with eAG(GA) ≥ 200 mg/dL. Conclusion: Our study used multiple parameters to evaluate blood glucose and renal function in patients with VH and found that hyperglycemia/DM and renal disease are closely associated with VH, especially in subjects with HCV infection. Patients with VH, especially those with HCV infection and hyperglycemia/DM, were particularly vulnerable to renal disease. [ABSTRACT FROM AUTHOR]

High quality 0.02 mol%, 0.05 mol%, and 0.08 mol% Fe: β-Ga2O3 single crystals were grown by the floating zone method. The crystal structure, optical, electrical, and thermal properties were measured and discussed. Fe: β-Ga2O3 single crystals showed transmittance of higher than 80% in the near infrared region. With the increase of the Fe doping concentration, the optical bandgaps reduced and room temperature resistivity increased. The resistivity of 0.08 mol% Fe: β-Ga2O3 crystal reached to 3.63 × 1011 Ω ⋅cm. The high resistivity Fe: β-Ga2O3 single crystals could be applied as the substrate for the high-power field effect transistors (FETs). [ABSTRACT FROM AUTHOR]