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1,469 results on '"Chen, J.Y."'

11. SPring-8 LEPS2 beamline: A facility to produce a multi-GeV photon beam via laser Compton scattering

Author

Muramatsu, N., Yosoi, M., Yorita, T., Ohashi, Y., Ahn, J.K., Ajimura, S., Asano, Y., Chang, W.C., Chen, J.Y., Daté, S., Gogami, T., Hamano, H., Hashimoto, T., Hiraiwa, T., Hotta, T., Ishikawa, T., Kasamatsu, Y., Katsuragawa, H., Kobayakawa, R., Kohri, H., Masumoto, S., Matsumura, Y., Miyabe, M., Mizutani, K., Morino, Y., Nakano, T., Nam, T., Niiyama, M., Nozawa, Y., Ohkuma, H., Ohnishi, H., Ohta, T., Oishi, M., Ozawa, K., Ryu, S.Y., Sada, Y., Saito, H., Shibukawa, T., Shimizu, H., Shirai, R., Shoji, M., Sumihama, M., Suzuki, S., Tanaka, S., Taniuchi, Y., Tokiyasu, A.O., Tomida, N., Tsuchikawa, Y., Watanabe, K., Yoon, C.J., and Yoshida, C.

Published
2022
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16. Studies on the impacts of the pore size and shape on deuterium retention in tungsten fuzzy nanostructures.

Author

Chen, J.Y., Dai, S.Y., Yang, K.R., Zu, C.R., Liu, D.P., Ni, W.Y., and Liu, S.G.

Subjects
*HYDROGEN isotopes, *TUNGSTEN, *NANOSTRUCTURES, *TRITIUM, *DEUTERIUM, *FUZZY neural networks
Abstract

Tritium retention in plasma-facing materials is a critical issue that can significantly impact the long-term and steady-state operation of fusion devices. The experiments conducted in the laboratory device MIES have confirmed that the presence of the tungsten (W) nanostructure (called 'fuzz') leads to a substantial retention of hydrogen isotopes within W fuzz layer. This observation motivates us to conduct dedicated modeling to investigate the influence of W nanostructures on deuterium (D) retention using the three-dimensional kinetic Monte Carlo code SURO-FUZZ. The SURO-FUZZ code offers a great flexibility in generating diverse microscopic structures of the W fuzzy surface through the quartet structure generation set (QSGS) approach, which allows us to explore the effects of the pore size and shape on D retention. In this study, several different W nanostructures generated by QSGS approach are utilized to conduct a comprehensive comparison between MIES experiments and SURO-FUZZ simulations. It is demonstrated that the simulated D retention can be brought into a reasonable agreement with the experimental data. On this basis, predictive estimations of D retention on EAST and ITER have been performed with SURO-FUZZ modeling. The simulation results indicate that the total D retention induced by W fuzz remains well below the administrative limit of 700 g. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Recurrence Risk Score Model for Evaluating the Impact of Postmastectomy Radiotherapy in Breast Cancer Patients with Pathologic Nodal Negative after Neoadjuvant Chemotherapy and Mastectomy

Author

Wang, D.Q., primary, Huang, Z., additional, Zhu, L., additional, Huang, X.B., additional, Wang, W.H., additional, Tie, J., additional, Shen, L., additional, Shi, M., additional, Chen, J.Y., additional, Liu, M., additional, Cheng, J., additional, Zhang, J., additional, Li, Y.X., additional, and Wang, S., additional

Published
2023
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25. Does Dual Anti-HER2 Therapy Increase Early Cardiac Toxicity in Comparison with Trastuzumab Alone in Breast Cancer Patients Receiving Adjuvant Radiotherapy? A Multicenter Retrospective Study

Author

Cao, L., primary, Yang, J., additional, Zhou, M., additional, Yu, B., additional, Lin, Q., additional, Yao, Y., additional, Wu, H.L., additional, Zhu, Q.W., additional, Ye, M., additional, Xie, H., additional, Wu, J.W., additional, and Chen, J.Y., additional

Published
2023
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38. A numerical investigation into the anomalous slight NOx increase when burning biodiesel; A new (old) theory

Author

Ban-Weiss, George A., Chen, J.Y., Buchholz, Bruce A., and Dibble, Robert W.

Subjects
Biodiesel, Diesel, Emissions, NOx, Increase, Double Bond
Abstract

Biodiesel is a notable alternative to petroleum derived diesel fuel because it comes from natural domestic sources and thus reduces dependence on diminishing petroleum fuel from foreign sources, it likely lowers lifecycle greenhouse gas emissions, and it lowers an engine’s emission of most pollutants as compared to petroleum derived diesel. However, the use of biodiesel often slightly increases a diesel engine’s emission of smog forming nitrogen oxides (NOx) relative to petroleum diesel. In this paper, previously proposed theories for this slight NOx increase are reviewed, including theories based on biodiesel’s cetane number, which leads to differing amounts of charge preheating, and theories based on the fuel’s bulk modulus, which affects injection timing. This paper proposes an additional theory for the slight NOx increase of biodiesel. Biodiesel typically contains more double bonded molecules than petroleum derived diesel. These double bonded molecules have a slightly higher adiabatic flame temperature, which leads to the increase in NOx production for biodiesel. Our theory was verified using numerical simulations to show a NOx increase, due to the double bonded molecules, that is consistent with observation. Further, the details of these numerical simulations show that NOx is predominantly due to the Zeldovich mechanism.

Published
2007

39. Contributors

Author

Anand Krishnan, R., primary, Anbazhagan, S., additional, Anirudhan, S., additional, Ansari, Jamal, additional, Arindam, M., additional, Brindha, K., additional, Chen, J.Y., additional, Chidambaram, S., additional, Chinnamuthu, M., additional, Chung, Sang Yong, additional, Dhanu Radha, V., additional, Elango, L., additional, Elzain, Hussam Eldin, additional, Gajendran, C., additional, Ganesh, N., additional, Gnanachandrasamy, G., additional, Gopinath, S., additional, Güler, Cüneyt, additional, Jesuraja, K., additional, Jha, Madan Kumar, additional, John, Cincy, additional, Jothibasu, A., additional, Karunanidhi, D., additional, Khan, Haris Hasan, additional, Khan, Arina, additional, Khatibi, Rahman, additional, Machiwal, Deepesh, additional, Magesh, N.S., additional, Manikandan, S., additional, Manisha, A., additional, Murali Krishnan, N., additional, Muthumaniraja, C.K., additional, Naderi, Keyvan, additional, Nadiri, Ata Allah, additional, Panda, Banajarani, additional, Paramasivam, C.R., additional, Prakash, R., additional, Prasanna, M.V., additional, Rajendran, M., additional, Rajesh, R., additional, Ramanathan, A.L., additional, Ramkumar, T., additional, Rejith, R.G., additional, Saharuba, P.M., additional, Saravanan, K., additional, Schneider, Michael, additional, Selvam, S., additional, Venkatramanan, S., additional, Sharma, Priyanka, additional, Singh, Prafull, additional, Srinivasamoorthy, K., additional, Sundararajan, M., additional, Thamarai, P., additional, Thilagavathi, R., additional, Thivya, C., additional, Tsai, Frank T.-C., additional, Vahedi, Fatemeh, additional, Vasudevan, S., additional, Verma, Pradipika, additional, and Vidhya, J., additional

Published
2019
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41. Mechanism of KMT5B haploinsufficiency in neurodevelopment in humans and mice.

Author

Sheppard, S.E., Bryant, L., Wickramasekara, R.N., Vaccaro, C., Robertson, B., Hallgren, J., Hulen, J., Watson, C.J., Faundes, V., Duffourd, Y., Lee, P., Simon, M.C., Cruz, X. de la, Padilla, N., Flores-Mendez, M., Akizu, N., Smiler, J., Pellegrino Da Silva, R., Li, D., March, M., Diaz-Rosado, A., Peixoto de Barcelos, I., Choa, Z.X., Lim, C.Y., Dubourg, C., Journel, H., Demurger, F., Mulhern, M., Akman, C., Lippa, N., Andrews, M., Baldridge, D., Constantino, J., Haeringen, A. van, Snoeck-Streef, I., Chow, P., Hing, A., Graham Jr, J.M., Au, M., Faivre, L., Shen, W., Mao, R., Palumbos, J., Viskochil, D., Gahl, W., Tifft, C., Macnamara, E., Hauser, N., Miller, R., Maffeo, J., Afenjar, A., Doummar, D., Keren, B., Arn, P., Macklin-Mantia, S., Meerschaut, I., Callewaert, B., Reis, A., Zweier, C., Brewer, C., Saggar, A., Smeland, M.F., Kumar, Ajith, Elmslie, F., Deshpande, C., Nizon, M., Cogne, B., Ierland, Y. van, Wilke, M., Slegtenhorst, M. van, Koudijs, S., Chen, J.Y., Dredge, D., Pier, D., Wortmann, S.B., Kamsteeg, E.J., Koch, J., Haynes, D., Pollack, L., Titheradge, H., Ranguin, K., Denommé-Pichon, A.S., Weber, S., Perez de la Fuente, R., Sanchez Del Pozo, J., Lezana Rosales, J.M., Joset, P., Steindl, K., Rauch, A., Mei, D., Mari, F., Guerrini, R., Lespinasse, J., Tran Mau-Them, F., Philippe, C., Dauriat, B., Raymond, L., Moutton, S., Cueto-González, A.M., Tan, T.Y., Mignot, C., Grotto, S., Renaldo, F., Drivas, T.G., Hennessy, L., Raper, A., Parenti, I., Kaiser, F.J., Kuechler, A., Busk, Ø.L., Islam, L., Siedlik, J.A., Henderson, L.B., Juusola, J., Person, R., Schnur, R.E., Vitobello, A., Banka, S., Bhoj, E.J., Stessman, H.A.F., Sheppard, S.E., Bryant, L., Wickramasekara, R.N., Vaccaro, C., Robertson, B., Hallgren, J., Hulen, J., Watson, C.J., Faundes, V., Duffourd, Y., Lee, P., Simon, M.C., Cruz, X. de la, Padilla, N., Flores-Mendez, M., Akizu, N., Smiler, J., Pellegrino Da Silva, R., Li, D., March, M., Diaz-Rosado, A., Peixoto de Barcelos, I., Choa, Z.X., Lim, C.Y., Dubourg, C., Journel, H., Demurger, F., Mulhern, M., Akman, C., Lippa, N., Andrews, M., Baldridge, D., Constantino, J., Haeringen, A. van, Snoeck-Streef, I., Chow, P., Hing, A., Graham Jr, J.M., Au, M., Faivre, L., Shen, W., Mao, R., Palumbos, J., Viskochil, D., Gahl, W., Tifft, C., Macnamara, E., Hauser, N., Miller, R., Maffeo, J., Afenjar, A., Doummar, D., Keren, B., Arn, P., Macklin-Mantia, S., Meerschaut, I., Callewaert, B., Reis, A., Zweier, C., Brewer, C., Saggar, A., Smeland, M.F., Kumar, Ajith, Elmslie, F., Deshpande, C., Nizon, M., Cogne, B., Ierland, Y. van, Wilke, M., Slegtenhorst, M. van, Koudijs, S., Chen, J.Y., Dredge, D., Pier, D., Wortmann, S.B., Kamsteeg, E.J., Koch, J., Haynes, D., Pollack, L., Titheradge, H., Ranguin, K., Denommé-Pichon, A.S., Weber, S., Perez de la Fuente, R., Sanchez Del Pozo, J., Lezana Rosales, J.M., Joset, P., Steindl, K., Rauch, A., Mei, D., Mari, F., Guerrini, R., Lespinasse, J., Tran Mau-Them, F., Philippe, C., Dauriat, B., Raymond, L., Moutton, S., Cueto-González, A.M., Tan, T.Y., Mignot, C., Grotto, S., Renaldo, F., Drivas, T.G., Hennessy, L., Raper, A., Parenti, I., Kaiser, F.J., Kuechler, A., Busk, Ø.L., Islam, L., Siedlik, J.A., Henderson, L.B., Juusola, J., Person, R., Schnur, R.E., Vitobello, A., Banka, S., Bhoj, E.J., and Stessman, H.A.F.

Abstract

Item does not contain fulltext, Pathogenic variants in KMT5B, a lysine methyltransferase, are associated with global developmental delay, macrocephaly, autism, and congenital anomalies (OMIM# 617788). Given the relatively recent discovery of this disorder, it has not been fully characterized. Deep phenotyping of the largest (n = 43) patient cohort to date identified that hypotonia and congenital heart defects are prominent features that were previously not associated with this syndrome. Both missense variants and putative loss-of-function variants resulted in slow growth in patient-derived cell lines. KMT5B homozygous knockout mice were smaller in size than their wild-type littermates but did not have significantly smaller brains, suggesting relative macrocephaly, also noted as a prominent clinical feature. RNA sequencing of patient lymphoblasts and Kmt5b haploinsufficient mouse brains identified differentially expressed pathways associated with nervous system development and function including axon guidance signaling. Overall, we identified additional pathogenic variants and clinical features in KMT5B-related neurodevelopmental disorder and provide insights into the molecular mechanisms of the disorder using multiple model systems.

Published
2023

43. ALS superbend magnet system

Author

Zbasnik, J., Wang, S.T., Chen, J.Y., DeVries, G.J., DeMarco, R., Fahmie, M., Geyer, A., Green, M.A., Harkins, J., Henderson, T., Hinkson, J., Hoyer, E.H., Krupnick, J., Marks, S., Ottens, F., Paterson, J.A., Pipersky, P., Portmann, G., Robin, D.A., Schlueter, R.D., Steier, C., Taylor, C.E., and Wahrer, R.

Subjects
Particle accelerators
Published
2000

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