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With the general environment of consumer purchasing power and the popularity of flexible supply chains, many warehousing companies have been based on their own needs for intelligent warehouse transformation, some warehouses for a comprehensive unmanned transformation, while some through the human-machine collaboration to control storage costs. But most of these warehouses to achieve transformation are only used to store one or a class of goods, such as the medicine and equipment industry. Able to carry out a large number and multiple items stored at the same time, intelligent warehouse construction is not popular enough, this paper will be the existing large-scale intelligent warehouse working principle, efficiency results and profit costs, and other aspects of the analysis to explore the large-scale warehouse intelligent transformation can bring specific benefits to the enterprise. The representatives of large, intelligent warehouses Amazon and Jingdong’s large and unmanned warehouses have a strong benchmark. In this paper, we select Jingdong’s large, unmanned warehouse, “Asia No. 1” and explain the working process and the role of hardware and software systems to find out what advantages the operation of these machines can bring to enterprises, what the competitiveness of intelligent equipment compared with manual labor, and how to help enterprises increase benefits and reduce costs.