137 results on '"Chen, Ci-Di"'
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2. Mobility of Cytochrome P450 in the Endoplasmic Reticulum Membrane
3. Activation of the Anti-Aging and Cognition-Enhancing Gene Klotho by CRISPR-dCas9 Transcriptional Effector Complex
4. The Anti-Aging Protein Klotho Enhances Remyelination Following Cuprizone-Induced Demyelination
5. The Anti-Aging and Tumor Suppressor Protein Klotho Enhances Differentiation of a Human Oligodendrocytic Hybrid Cell Line
6. Insulin Stimulates the Cleavage and Release of the Extracellular Domain of Klotho by ADAM10 and ADAM17
7. Furin initiates gelsolin familial amyloidosis in the Golgi through a defect in Ca2+ stabilization
8. A method to specifically activate the Klotho promoter by using zinc finger proteins constructed from modular building blocks and from naturally engineered Egr1 transcription factor backbone
9. Identification of the cleavage sites leading to the shed forms of human and mouse anti-aging and cognition-enhancing protein Klotho
10. Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress
11. Cell-type dependent modulation of Notch signaling by the amyloid precursor protein
12. Substitutions in the C-terminal portion of the catalytic domain partially reverse assembly defects introduced by mutations in the N-terminal linker sequence of cytochrome P450 2C2
13. Age-dependent accumulation of ubiquitinated 2′,3′-cyclic nucleotide 3′-phosphodiesterase in myelin lipid rafts
14. Visualization of APP dimerization and APP-Notch2 heterodimerization in living cells using bimolecular fluorescence complementation
15. Production of androsta-1,4-diene-3,17-dione from cholesterol using two-step microbial transformation
16. Identification and localization of major soluble vitreous proteins in human ocular tissue
17. Small Molecule Amyloid-β Protein Precursor Processing Modulators Lower Amyloid-β Peptide Levels via cKit Signaling
18. Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein
19. Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress.
20. Klotho, PTSD, and advanced epigenetic age in cortical tissue
21. Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1G93A) Mouse Model of ALS.
22. Comparable dimerization found in wildtype and familial Alzheimer’s disease amyloid precursor protein mutants
23. Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerization
24. Identification of Cleavage Sites Leading to the Shed Form of the Anti-Aging Protein Klotho
25. The Neuroprotective Effect of Klotho is Mediated via Regulation of Members of the Redox System
26. The Anti-Aging and Tumor Suppressor Protein Klotho Enhances Differentiation of a Human Oligodendrocytic Hybrid Cell Line
27. P3-068: Klotho gene protects primary hippocampal neurons from oxidative stress
28. O4–06–02: Genetic variation in PLXNA4 associated with susceptibility of Alzheimer's disease through tau phosphorylation
29. Detection of Amyloid-β Protein Precursor Homo-Interactions Using Beta-Galactosidase Enzyme Fragment Complementation
30. P3-469: Development of Klotho enhancers as novel therapeutics for Alzheimer's disease
31. P2-291: The functions of the anti-aging protein Klotho in the brain
32. O1-03-07: Klotho, aging and Alzheimer's
33. P2-362: Detection of amyloid precursor protein dimerization in cells using enzyme fragment complementation and bimolecular fluorescent complementation
34. P4-186: Modulating Klotho expression to protect against age-induced neurodegeneration
35. Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein
36. P4-077: Modulation of amyloid precursor protein-processing by oxysterol-binding protein
37. P4-002: Bimolecular fluorescence complementation studies of APP homodimerization and heterodimerization
38. Amyloid precursor protein interacts with notch receptors
39. Gene Expression Changes Associated with the Endoplasmic Reticulum Stress Response Induced by Microsomal Cytochrome P450 Overproduction
40. Stability of RNA from the Retina and Retinal Pigment Epithelium in a Porcine Model Simulating Human Eye Bank Conditions
41. N-Terminal Deletions and His-Tag Fusions Dramatically Affect Expression of Cytochrome P450 2C2 in Bacteria
42. Stage-Specific Assays to Study Biosynthetic Cargo Selection and Role of SNAREs in Export from the Endoplasmic Reticulum and Delivery to the Golgi
43. Cytochromes P450 2C1/2 and P450 2E1 Are Retained in the Endoplasmic Reticulum Membrane by Different Mechanisms
44. A Conserved Proline-rich Sequence between the N-terminal Signal-anchor and Catalytic Domains Is Required for Assembly of Functional Cytochrome P450 2C2
45. Efficient Assembly of Functional Cytochrome P450 2C2 Requires a Spacer Sequence between the N-terminal Signal Anchor and Catalytic Domains
46. Klotho gene protects primary hippocampal neurons from oxidative stress
47. Genetic variation in PLXNA4 associated with susceptibility of Alzheimer’s disease through tau phosphorylation
48. Different Structural Requirements at Specific Proline Residue Positions in the Conserved Proline-rich Region of Cytochrome P450 2C2
49. The Cytoplasmic and N-terminal Transmembrane Domains of Cytochrome P450 Contain Independent Signals for Retention in the Endoplasmic Reticulum
50. Development of Klotho enhancers as novel therapeutics for Alzheimer's disease
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