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1,961 results on '"Chen, Chunying"'

2. Multidisciplinary and multiscale nanoscience research roadmap based on large scientific facilities

Author

Zeng, Yuan, Zhang, Shuhan, Guo, Yuecong, Cong, Yalin, Ding, Xu, Li, Peihua, Lin, Yunxiang, Ren, Wenzhi, Su, Hui, Sun, Weigang, Xu, Liuxin, Zhang, Guikai, Chen, Shihua, Chen, Yu, Cheng, Weiren, Chu, Shengqi, Guan, Yong, Han, Jinru, Lin, Jie, Liu, Hengjie, Liu, Zheyi, Luo, Pan, Meng, Fanchun, Qiao, Sicong, Song, Zongyin, Wang, Ying, Wu, Zhao, Yang, Chenyu, Yang, Meng, Yang, Shirui, Yin, Zi, Yin, Zhibin, Zhang, Pengjun, Zhang, Hongyu, Zheng, Pingping, Zhou, Jia, Zhou, Wanlin, An, Pengfei, Cheng, He, Fan, Chunhai, Huang, Xingjiu, Lei, Yong, Li, Lina, Li, Mu, Liu, Qinghua, Peng, Shuming, Song, Li, Sun, Zhihu, Tian, Yangchao, Wang, Fangjun, Wang, Lihua, Wang, Liming, Wei, Shiqiang, Wu, Aiguo, Xiao, Chunlei, Yang, Xueming, Yin, Panchao, Zhang, Jing, Zhang, Mingxin, Wang, Yaling, and Chen, Chunying

Published
2024
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5. Standard: human intestine-on-a-chip

Author

Liu, Haitao, Wang, Yaqing, Zhang, Xu, Zhang, Min, Wang, Peng, Shang, Jing, Li, Zhongqiang, Gong, Likun, Guo, Jiabin, Sun, Wei, Pi, Jingbo, Li, Xianliang, Ding, Wei, Wang, Dianbing, Li, Zhongyu, Zhang, Jingzhong, Wang, Lan, Geng, Xingchao, Yang, Ruifu, Zhou, Pingkun, Tang, Wanjin, Zhang, Xian’en, Chen, Chunying, Yang, Shengli, and Qin, Jianhua

Published
2024
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16. Biotransformation of nanoplastics in human plasma and their permeation through a model in vitro blood-brain barrier: An in-depth quantitative analysis

Author

Abdolahpur Monikh, Fazel, Lehtonen, Šárka, Kekäläinen, Jukka, Karkossa, Isabel, Auriola, Seppo, Schubert, Kristin, Zanut, Alessandra, Peltonen, Sanni, Niskanen, Jonna, Bandekar, Mandar, von Bergen, Martin, Leskinen, Jari T.T., Koistinen, Arto, Bogialli, Sara, Guo, Zhiling, Kukkonen, Jussi V.K., Chen, Chunying, and Lynch, Iseult

Published
2024
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19. Understanding Nanomaterial–Liver Interactions to Facilitate the Development of Safer Nanoapplications

Author

Li, Jiulong, Chen, Chunying, and Xia, Tian

Subjects
Engineering, Digestive Diseases, Chronic Liver Disease and Cirrhosis, Nanotechnology, Bioengineering, Liver Disease, Oral and gastrointestinal, Endothelial Cells, Kupffer Cells, Liver, Nanostructures, cell-type-specific uptake, mode of action, nano-liver interaction, nanomedicine, nanosafety, Physical Sciences, Chemical Sciences, Nanoscience & Nanotechnology, Chemical sciences, Physical sciences
Abstract

Nanomaterials (NMs) are widely used in commercial and medical products, such as cosmetics, vaccines, and drug carriers. Exposure to NMs via various routes such as dermal, inhalation, and ingestion has been shown to gain access to the systemic circulation, resulting in the accumulation of NMs in the liver. The unique organ structures and blood flow features facilitate the liver sequestration of NMs, which may cause adverse effects in the liver. Currently, most in vivo studies are focused on NMs accumulation at the organ level and evaluation of the gross changes in liver structure and functions, however, cell-type-specific uptake and responses, as well as the molecular mechanisms at cellular levels leading to effects at organ levels are lagging. Herein, the authors systematically review diverse interactions of NMs with the liver, specifically on major liver cell types including Kupffer cells (KCs), liver sinusoidal endothelial cells (LSECs), hepatic stellate cells (HSCs), and hepatocytes as well as the detailed molecular mechanisms involved. In addition, the knowledge gained on nano-liver interactions that can facilitate the development of safer nanoproducts and nanomedicine is also reviewed.

Published
2022

28. Nanotoxicology and nanomedicine: The Yin and Yang of nano-bio interactions for the new decade

Author

Bondarenko, Olesja, Mortimer, Monika, Kahru, Anne, Feliu, Neus, Javed, Ibrahim, Kakinen, Aleksandr, Lin, Sijie, Xia, Tian, Song, Yang, Davis, Thomas P, Lynch, Iseult, Parak, Wolfgang J, Leong, David Tai, Ke, Pu Chun, Chen, Chunying, and Zhao, Yuliang

Subjects
Nanotechnology, Bioengineering, Nanotoxicology, Nanomedicine, Microbiome, Coronavirus, Protein corona, NanoEL, coronavirus, microbiome, nanomedicine, nanotoxicology, protein corona, Biomedical Engineering, Nanoscience & Nanotechnology
Abstract

Nanotoxicology and nanomedicine are two sub-disciplines of nanotechnology focusing on the phenomena, mechanisms, and engineering at the nano-bio interface. For the better part of the past three decades, these two disciplines have been largely developing independently of each other. Yet recent breakthroughs in microbiome research and the current COVID-19 pandemic demonstrate that holistic approaches are crucial for solving grand challenges in global health. Here we show the Yin and Yang relationship between the two fields by highlighting their shared goals of making safer nanomaterials, improved cellular and organism models, as well as advanced methodologies. We focus on the transferable knowledge between the two fields as nanotoxicological research is moving from pristine to functional nanomaterials, while inorganic nanomaterials - the main subjects of nanotoxicology - have become an emerging source for the development of nanomedicines. We call for a close partnership between the two fields in the new decade, to harness the full potential of nanotechnology for benefiting human health and environmental safety.

Published
2021

29. Inherited and acquired corona of coronavirus in the host: Inspiration from the biomolecular corona of nanoparticles

Author

Gao, Jie, Zeng, Li, Yao, Linlin, Wang, Ziniu, Yang, Xiaoxi, Shi, Jianbo, Hu, Ligang, Liu, Qian, Chen, Chunying, Xia, Tian, Qu, Guangbo, Zhang, Xian-En, and Jiang, Guibin

Subjects
COVID-19, Coronaviruses, Biomolecular corona, Acquired corona, Host environments, Infection, Biomedical Engineering, Nanotechnology, Nanoscience & Nanotechnology
Abstract

The family of coronavirus are named for their crown shape. Encoded by the genetic material inherited from the coronavirus itself, this intrinsic well-known "viral corona" is considered an "inherited corona". After contact with mucosa or the entrance into the host, bare coronaviruses can become covered by a group of dissolved biomolecules to form one or multiple layers of biomolecules. The layers acquired from the surrounding environment are named the "acquired corona". We highlight here the possible role of the acquired corona in the pathogenesis of coronaviruses, which will generate fresh insight into the nature of various coronavirus-host interactions.

Published
2021

31. X‑ray-Based Techniques to Study the Nano–Bio Interface

Author

Sanchez-Cano, Carlos, Alvarez-Puebla, Ramon A, Abendroth, John M, Beck, Tobias, Blick, Robert, Cao, Yuan, Caruso, Frank, Chakraborty, Indranath, Chapman, Henry N, Chen, Chunying, Cohen, Bruce E, Conceição, Andre LC, Cormode, David P, Cui, Daxiang, Dawson, Kenneth A, Falkenberg, Gerald, Fan, Chunhai, Feliu, Neus, Gao, Mingyuan, Gargioni, Elisabetta, Glüer, Claus-C, Grüner, Florian, Hassan, Moustapha, Hu, Yong, Huang, Yalan, Huber, Samuel, Huse, Nils, Kang, Yanan, Khademhosseini, Ali, Keller, Thomas F, Körnig, Christian, Kotov, Nicholas A, Koziej, Dorota, Liang, Xing-Jie, Liu, Beibei, Liu, Sijin, Liu, Yang, Liu, Ziyao, Liz-Marzán, Luis M, Ma, Xiaowei, Machicote, Andres, Maison, Wolfgang, Mancuso, Adrian P, Megahed, Saad, Nickel, Bert, Otto, Ferdinand, Palencia, Cristina, Pascarelli, Sakura, Pearson, Arwen, Peñate-Medina, Oula, Qi, Bing, Rädler, Joachim, Richardson, Joseph J, Rosenhahn, Axel, Rothkamm, Kai, Rübhausen, Michael, Sanyal, Milan K, Schaak, Raymond E, Schlemmer, Heinz-Peter, Schmidt, Marius, Schmutzler, Oliver, Schotten, Theo, Schulz, Florian, Sood, AK, Spiers, Kathryn M, Staufer, Theresa, Stemer, Dominik M, Stierle, Andreas, Sun, Xing, Tsakanova, Gohar, Weiss, Paul S, Weller, Horst, Westermeier, Fabian, Xu, Ming, Yan, Huijie, Zeng, Yuan, Zhao, Ying, Zhao, Yuliang, Zhu, Dingcheng, Zhu, Ying, and Parak, Wolfgang J

Subjects
Medical Biotechnology, Biomedical and Clinical Sciences, Physical Sciences, Bioengineering, Nanotechnology, Generic health relevance, Lasers, Nanoparticles, Radiography, Synchrotrons, X-Rays, nano-bio interface, X-ray techniques, synchrotron radiation, imaging, nanoparticles, delivery, degradation, spectroscopy, nano−bio interface, Nanoscience & Nanotechnology
Abstract

X-ray-based analytics are routinely applied in many fields, including physics, chemistry, materials science, and engineering. The full potential of such techniques in the life sciences and medicine, however, has not yet been fully exploited. We highlight current and upcoming advances in this direction. We describe different X-ray-based methodologies (including those performed at synchrotron light sources and X-ray free-electron lasers) and their potentials for application to investigate the nano-bio interface. The discussion is predominantly guided by asking how such methods could better help to understand and to improve nanoparticle-based drug delivery, though the concepts also apply to nano-bio interactions in general. We discuss current limitations and how they might be overcome, particularly for future use in vivo.

Published
2021

37. A nanomaterial targeting the spike protein captures SARS-CoV-2 variants and promotes viral elimination

Author

Zhang, Guofang, Cong, Yalin, Liu, Feng-Liang, Sun, Jiufeng, Zhang, Jiantian, Cao, Guoli, Zhou, Lingqiang, Yang, Wenjie, Song, Qingle, Wang, Fangjun, Liu, Ke, Qu, Jing, Wang, Jing, He, Min, Feng, Shun, Baimanov, Didar, Xu, Wei, Luo, Rong-Hua, Long, Xin-Yan, Liao, Shumin, Fan, Yunping, Li, Yu-Feng, Li, Bai, Shao, Ximing, Wang, Guocheng, Fang, Lijing, Wang, Huaiyu, Yu, Xue-Feng, Chang, Yan-Zhong, Zhao, Yuliang, Li, Liang, Yu, Peng, Zheng, Yong-Tang, Boraschi, Diana, Li, Hongchang, Chen, Chunying, Wang, Liming, and Li, Yang

Published
2022
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41. Publisher Correction: On the issue of transparency and reproducibility in nanomedicine

Author

Leong, Hon S, Butler, Kimberly S, Brinker, C Jeffrey, Azzawi, May, Conlan, Steve, Dufès, Christine, Owen, Andrew, Rannard, Steve, Scott, Chris, Chen, Chunying, Dobrovolskaia, Marina A, Kozlov, Serguei V, Prina-Mello, Adriele, Schmid, Ruth, Wick, Peter, Caputo, Fanny, Boisseau, Patrick, Crist, Rachael M, McNeil, Scott E, Fadeel, Bengt, Tran, Lang, Hansen, Steffen Foss, Hartmann, Nanna B, Clausen, Lauge PW, Skjolding, Lars M, Baun, Anders, Ågerstrand, Marlene, Gu, Zhen, Lamprou, Dimitrios A, Hoskins, Clare, Huang, Leaf, Song, Wantong, Cao, Huiliang, Liu, Xuanyong, Jandt, Klaus D, Jiang, Wen, Kim, Betty YS, Wheeler, Korin E, Chetwynd, Andrew J, Lynch, Iseult, Moghimi, Seyed Moein, Nel, André, Xia, Tian, Weiss, Paul S, Sarmento, Bruno, das Neves, José, Santos, Hélder A, Santos, Luis, Mitragotri, Samir, Little, Steve, Peer, Dan, Amiji, Mansoor M, Alonso, Maria José, Petri-Fink, Alke, Balog, Sandor, Lee, Aaron, Drasler, Barbara, Rothen-Rutishauser, Barbara, Wilhelm, Stefan, Acar, Handan, Harrison, Roger G, Mao, Chuanbin, Mukherjee, Priyabrata, Ramesh, Rajagopal, McNally, Lacey R, Busatto, Sara, Wolfram, Joy, Bergese, Paolo, Ferrari, Mauro, Fang, Ronnie H, Zhang, Liangfang, Zheng, Jie, Peng, Chuanqi, Du, Bujie, Yu, Mengxiao, Charron, Danielle M, Zheng, Gang, and Pastore, Chiara

Subjects
Nanoscience & Nanotechnology
Abstract

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Published
2019

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