280 results on '"Chen, Catherine Z."'
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2. Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics
3. Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation
4. Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants
5. Reversal gene expression assessment for drug repurposing, a case study of glioblastoma.
6. A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry
7. Mitoxantrone modulates a heparan sulfate-spike complex to inhibit SARS-CoV-2 infection
8. Rottlerin inhibits La Crosse virus-induced encephalitis in mice and blocks release of replicating virus from the Golgi body in neurons
9. Identification of SARS-CoV-2 viral entry inhibitors using machine learning and cell-based pseudotyped particle assay
10. Synergistic and Antagonistic Drug Combinations against SARS-CoV-2
11. RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery
12. Drug Discovery Strategies for SARS-CoV-2
13. Cell-Based No-Wash Fluorescence Assays for Compound Screens Using a Fluorescence Cytometry Plate Reader
14. Biological activity-based modeling identifies antiviral leads against SARS-CoV-2
15. A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity
16. Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics
17. Identification of Potent ADCK3 Inhibitors through Structure-Based Virtual Screening.
18. Advancing precision medicine with personalized drug screening
19. Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile
20. A Role for Yip1p in COPII Vesicle Biogenesis
21. SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy
22. A Protocol for Culture and Characterization of Human Induced Pluripotent Stem Cells After Induction
23. Generation of induced pluripotent stem cell lines TRNDi037-A and TRNDi038-A from two patients with Alagille syndrome carrying heterozygous JAG1 mutations
24. Heparan sulfate promotes ACE2 super-cluster assembly to enhance SARS-CoV-2-associated syncytium formation
25. Investigation of Interactions at the Extracellular Loops of the Relaxin Family Peptide Receptor 1 (RXFP1)
26. Structural Basis for Inactivation of Giardia lamblia Carbamate Kinase by Disulfiram
27. An Alternative Direct Compound Dispensing Method Using the HP D300 Digital Dispenser
28. Identification of Small-Molecule Agonists of Human Relaxin Family Receptor 1 (RXFP1) by Using a Homogenous Cell-Based cAMP Assay
29. Repurposing a novel parathyroid hormone analogue to treat hypoparathyroidism
30. Preclinical Pharmacokinetics and In Vitro Properties of GS-441524, a Potential Oral Drug Candidate for COVID-19 Treatment
31. A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike
32. Therapeutic Strategies For Tay-Sachs Disease
33. Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19
34. Graph Convolutional Network-Based Screening Strategy for Rapid Identification of SARS-CoV-2 Cell-Entry Inhibitors
35. Efficient Identification of Anti-SARS-CoV-2 Compounds Using Chemical Structure- and Biological Activity-Based Modeling
36. A Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19
37. SARS-CoV-2 Nucleocapsid Protein TR-FRET Assay Amenable to High Throughput Screening
38. Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection
39. Camel nanobodies broadly neutralize SARS-CoV-2 variants
40. A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike
41. Mitoxantrone modulates a glycosaminoglycan-spike complex to inhibit SARS-CoV-2 infection
42. A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry
43. Two high-throughput screening assays for aberrant RNA–protein interactions in myotonic dystrophy type 1
44. Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium
45. Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects
46. Hybrid In Silico Approach Reveals Novel Inhibitors of Multiple SARS-CoV-2 Variants
47. Discovery of Small Molecule Entry Inhibitors Targeting the Fusion Peptide of SARS-CoV-2 Spike Protein
48. A SARS-CoV-2 nucleocapsid protein TR-FRET assay amenable to high-throughput screening
49. Generation of an induced pluripotent stem cell line (TRNDi031-A) from a patient with Alagille syndrome type 1 carrying a heterozygous p. C312X (c. 936 T > A) mutation in JAGGED-1
50. A hybrid in silico approach reveals novel inhibitors of multiple SARS-CoV-2 variants
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