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Your search keyword '"Chee Yeun Chung"' showing total 44 results

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44 results on '"Chee Yeun Chung"'

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1. Automated algorithm development to assess survival of human neurons using longitudinal single-cell tracking: Application to synucleinopathy

2. Patient-derived three-dimensional cortical neurospheres to model Parkinson’s disease

3. Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity

4. Targeting de novo lipid synthesis induces lipotoxicity and impairs DNA damage repair in glioblastoma mouse models

5. Rapid iPSC inclusionopathy models shed light on formation, consequence and molecular subtype of α-synuclein inclusions

6. Divergent MEK/ERK and AMPK signaling dictate lipogenic plasticity and dependence on fatty acid synthesis in Glioblastoma

7. A Brain-Penetrant Stearoyl-CoA Desaturase Inhibitor Reverses α-Synuclein Toxicity

8. TMET-25. MEK/ERK AND AMPK SIGNALING DICTATE VULNERABILITY TO FATTY ACID DESATURATION INHIBITION IN GLIOBLASTOMA

9. Non-clinical Pharmacology of YTX-7739: a Clinical Stage Stearoyl-CoA Desaturase Inhibitor Being Developed for Parkinson's Disease

10. Patient-Derived Three-Dimensional Cortical Neurospheres to Model Parkinson’s Disease

11. EXTH-23. PRECLINICAL EFFICACY OF A TARGETED, BRAIN PENETRANT INHIBITOR OF FATTY ACID DESATURATION IN GLIOBLASTOMA

12. In Situ Peroxidase Labeling and Mass Spectrometry of Alpha-Synuclein in Rat Cortical Neurons

13. In Situ Peroxidase Labeling and Mass Spectrometry of Alpha-Synuclein in Rat Cortical Neurons

14. FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome

15. Calcineurin determines toxic versus beneficial responses to alpha-synuclein

16. Yeast Reveal a 'Druggable' Rsp5/Nedd4 Network that Ameliorates α-Synuclein Toxicity in Neurons

17. Identification and Rescue of α-Synuclein Toxicity in Parkinson Patient–Derived Neurons

18. Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways

19. SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones

20. From Yeast to Patients: The Audacity and Vision of Susan Lindquist

21. Functional Links Between Aβ Toxicity, Endocytic Trafficking, and Alzheimer’s Disease Risk Factors in Yeast

22. Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity

23. The Toll-Like Receptor-3 Agonist Polyinosinic:Polycytidylic Acid Triggers Nigrostriatal Dopaminergic Degeneration

24. Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV α-Synucleinopathy

25. An Endogenous Serine/Threonine Protein Phosphatase Inhibitor, G-Substrate, Reduces Vulnerability in Models of Parkinson's Disease

26. Toward stem cell-based phenotypic screens for neurodegenerative diseases

27. In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons

28. From yeast to patient neurons and back again: powerful new discovery platform

29. Endogenous and exogenous Na-K-Cl cotransporter expression in a low K-resistant mutant MDCK cell line

30. The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons

31. Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression

32. FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome.

33. Identification and Rescue of ɑ-Synuclein Toxicity in Parkinson Patient-Derived Neurons.

34. SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones.

35. The Toll-Like Receptor-3 Agonist Polyinosinic:Polycytidylic Acid Triggers Nigrostriatal Dopaminergic Degeneration.

36. The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons.

37. High regulatability favors genetic selection in SLC18A2, a vesicular monoamine transporter essential for life.

38. Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression.

39. Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV α-Synucleinopathy.

40. An Endogenous Serine/Threonine Protein Phosphatase Inhibitor, G-Substrate, Reduces Vulnerability in Models of Parkinson's Disease.

41. Endogenous and exogenous Na-K-Cl cotransporter expression in a low K-resistant mutant MDCK cell...

42. Functional Integration of Dopaminergic Neurons Directly Converted from Mouse Fibroblasts

43. Toward stem cell-based phenotypic screens for neurodegenerative diseases.

44. Yeast Reveal a "Druggable" Rsp5/Nedd4 Network that Ameliorates a-Synuclein Toxicity in Neurons.

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