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3. The BM@N spectrometer at the NICA accelerator complex

Author

Afanasiev, S., Agakishiev, G., Aleksandrov, E., Aleksandrov, I., Alekseev, P., Alishina, K., Astakhov, V., Atkin, E., Aushev, T., Azorskiy, V., Babkin, V., Balashov, N., Barak, R., Baranov, A., Baranov, D., Baranova, N., Barbashina, N., Baznat, M., Bazylev, S., Belov, M., Blau, D., Bocharnikov, V., Bogdanova, G., Bolozdynya, A., Bondar, E., Boos, E., Buryakov, M., Buzin, S., Chebotov, A., Chemezov, D., Chen, J. H., Demanov, A., Dementev, D., Dmitriev, A., Drnoyan, J., Dryablov, D., Dryuk, A., Dubinchik, B., Dulov, P., Egorov, A., Egorov, D., Elsha, V., Fediunin, A., Fedosimova, A., Filippov, I., Filozova, I., Finogeev, D., Gabdrakhmanov, I., Galavanov, A., Gavrischuk, O., Gertsenberger, K., Golosov, O., Golovatyuk, V., Grigoriev, P., Golubeva, M., Guber, F., Ibraimova, S., Idrisov, D., Idrissova, T., Iusupova, A., Ivashkin, A., Izvestnyy, A., Kabadzhov, V., Kanokova, Sh., Kapishin, M., Kapitonov, I., Karjavin, V., Karmanov, D., Karpushkin, N., Kattabekov, R., Kekelidze, V., Khabarov, S., Kharlamov, P., Khudaiberdyev, G., Khukhaeva, A., Khvorostukhin, A., Kiryushin, Yu., Klimai, P., Kolesnikov, V., Kolozhvari, A., Kopylov, Yu., Korolev, M., Kovachev, L., Kovalev, I., Kruglova, I., Kovalev, Yu., Kozlov, I., Kozlov, V., Kuklin, S., Kulish, E., Kurganov, A., Kutergina, V., Kuznetsov, A., Ladygin, E., Lanskoy, D., Lashmanov, N., Lebedev, I., Lenivenko, V., Lednicky, R., Leontiev, V., Liapin, D., Litvinenko, E., Ma, Y. G., Makankin, A., Makhnev, A., Malakhov, A., Mamaev, M., Martemianov, A., Martovitsky, E., Mashitsin, K., Merkin, M., Merts, S., Morozov, S., Murin, Yu., Musaev, K., Musulmanbekov, G., Myasnikov, A., Myktybekov, D., Nagdasev, R., Nemnyugin, S., Nikitin, D., Novozhilov, S., Olimov, Kh., Olimov, K., Palichik, V., Parfenov, P., Pelevanyuk, I., Peresunko, D., Piyadin, S., Platonova, M., Plotnikov, V., Podgainy, D., Pukhaeva, N., Ratnikov, F., Reshetova, S., Rogov, V., Romanov, I., Rufanov, I., Rukoyatkin, P., Rumyantsev, M., Rybakov, T., Sakulin, D., Sedykh, S., Serebryakov, D., Shabanov, A., Segal, I., Semak, A., Sergeev, S., Serikkanov, A., Sheremetev, A., Sheremeteva, A., Shchipunov, A., Shitenkov, M., Shopova, M., Shumikhin, V., Shutov, A., Shutov, V., Shodmonov, M., Slepnev, I., Slepnev, V., Slepov, I., Smirnov, A., Smolyanin, T., Solomin, A., Sorin, A., Sosnovtsev, V., Spaskov, V., Stavinskiy, A., Stekhanov, V., Stepanenko, Yu., Streletskaya, E., Streltsova, O., Strikhanov, M., Sukhov, E., Suvarieva, D., Taer, G., Taranenko, A., Tarasov, N., Tarasov, O., Teremkov, P., Terletsky, A., Teryaev, O., Tcholakov, V., Tikhomirov, V., Timoshenko, A., Tojiboev, O., Topilin, N., Tretyakova, T., Troshin, V., Truttse, A., Tserruya, I., Tskhay, V., Tyapkin, I., Ustinov, V., Vasendina, V., Velichkov, V., Volkov, V., Voronin, A., Voytishin, N., Yuldashev, B., Yurevich, V., Zamiatin, N., Zavertyaev, M., Zhang, S., Zhavoronkova, I., Zhezher, V., Zhigareva, N., Zinchenko, A., Zubankov, A., Zubarev, E., and Zuev, M.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

BM@N (Baryonic Matter at Nuclotron) is the first experiment operating and taking data at the Nuclotron/NICA ion-accelerating complex.The aim of the BM@N experiment is to study interactions of relativistic heavy-ion beams with fixed targets. We present a technical description of the BM@N spectrometer including all its subsystems., Comment: 34 pages, 47 figures, 6 tables

Published
2023

7. Production of $\pi^+$ and $K^+$ mesons in argon-nucleus interactions at 3.2 AGeV

Author

Afanasiev, S., Agakishiev, G., Aleksandrov, E., Aleksandrov, I., Alekseev, P., Alishina, K., Atkin, E., Aushev, T., Babkin, V., Balashov, N., Baranov, A., Baranov, D., Baranova, N., Barbashina, N., Baznat, M., Bazylev, S., Belov, M., Blau, D., Bogdanova, G., Bogoslovsky, D., Bolozdynya, A., Boos, E., Buryakov, M., Buzin, S., Chebotov, A., Chen, J., Dementev, D., Dmitriev, A., Dryablov, D., Dryuk, A., Dulov, P., Egorov, D., Elsha, V., Fediunin, A., Filippov, I., Filozova, I., Finogeev, D., Gabdrakhmanov, I., Galavanov, A., Gavrischuk, O., Gertsenberger, K., Golovatyuk, V., Golubeva, M., Guber, F., Iusupova, A., Ivashkin, A., Izvestnyy, A., Kabadzhov, V., Kapishin, M., Kapitonov, I., Karjavin, V., Karmanov, D., Karpushkin, N., Kattabekov, R., Kekelidze, V., Khabarov, S., Kharlamov, P., Khukhaeva, A., Khvorostukhin, A., Kiryushin, Yu., Klimai, P., Klimansky, D., Kolesnikov, V., Kolozhvari, A., Kopylov, Yu., Korolev, M., Kovachev, L., Kovalev, I., Kovalev, Yu., Kozlov, I., Kozlov, V., Kudryashov, I., Kuklin, S., Kulish, E., Kurganov, A., Kuznetsov, A., Ladygin, E., Lanskoy, D., Lashmanov, N., Lenivenko, V., Lednický, R., Leontiev, V., Litvinenko, E., Ma, Yu-G., Makankin, A., Makhnev, A., Malakhov, A., Martemianov, A., Martovitsky, E., Mashitsin, K., Merkin, M., Merts, S., Morozov, A., Morozov, S., Murin, Yu., Musulmanbekov, G., Myasnikov, A., Nagdasev, R., Nekrasowa, E., Nemnyugin, S., Nikitin, D., Novozhilov, S., Palchik, V., Pelevanyuk, I., Peresunko, D., Petukhov, O., Petukhov, Yu., Piyadin, S., Platonova, M., Plotnikov, V., Podgainy, D., Rogov, V., Rufanov, I., Rukoyatkin, P., Rumyantsev, M., Sakulin, D., Sergeev, S., Sheremetev, A., Sheremeteva, A., Shchipunov, A., Shitenkov, M., Shopova, M., Shumikhin, V., Shutov, A., Shutov, V., Slepnev, I., Slepnev, V., Slepov, I., Solomin, A., Sorin, A., Sosnovtsev, V., Spaskov, V., Stavinskiy, A., Stepanenko, Yu., Streletskaya, E., Streltsova, O., Strikhanov, M., Sukhov, N., Suvarieva, D., Taer, G., Tarasov, N., Tarasov, O., Teremkov, P., Terletsky, A., Teryaev, O., Tcholakov, V., Tikhomirov, V., Timoshenko, A., Topilin, N., Tretyakova, T., Tskhay, V., Tsvetkov, E., Tyapkin, I., Vasendina, V., Velichkov, V., Volkov, V., Voronin, A., Voytishin, N., Yurevich, V., Yumatova, I., Zamiatin, N., Zavertyaev, M., Zhang, S., Zherebtsova, E., Zhezher, V., Zhigareva, N., Zinchenko, A., Zubankov, A., Zubarev, E., and Zuev, M.

Subjects
High Energy Physics - Experiment, Nuclear Experiment
Abstract

First physics results of the BM@N experiment at the Nuclotron/NICA complex are presented on {\pi}+ and K+ meson production in interactions of an argon beam with fixed targets of C, Al, Cu, Sn and Pb at 3.2 AGeV. Transverse momentum distributions, rapidity spectra and multiplicities of $\pi^+$ and $K^+$ mesons are measured. The results are compared with predictions of theoretical models and with other measurements at lower energies., Comment: 29 pages, 20 figures

Published
2023
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9. Features of both immune and psycho-emotional factors in the adaptive reactions of first-year students

Author

R. T. Urazmambetov, S. A. Chebotov, and T. V. Loboda

Subjects
adaptation, immune homeostasis, psychological stress, innate immunity, Medicine (General), R5-920
Abstract

Objective: comparative characteristics of indicators of psycho-emotional and immune statuses of first-year students in various conditions of the educational process.Materials and methods: 2nd groups of first-year students of Rostov State Medical University from the medical and preventive faculty (18 people) and the military training center (17 people) were examined. They were all comparable in age (19 ±1 and 19±2 years), gender (all men), physical condition (corresponded to the I-st health group). The immune status was assessed at the Research Institute of Clinical Immunology using standard methodological approaches. Psychological testing was carried out using the Spielberger-Khanin scale, A. Beck's depression diagnostic methodology, and K. Rogers and R. Diamond questionnaire.Results: the differences in the immune response system between the compared groups were revealed only in relation to the parameters characterizing innate immunity. In relation to Medical and Preventive Faculty students, the functional capabilities of natural killers in Military Training Centre students are reduced and the expression of one of the most indicative pattern-recognizing receptors by monocytes is diminished. The analysis of the obtained data of the psychological questionnaire showed that the students of the Military Training Centredemonstrate a lower degree of situational and personal anxiety with a lower degree of adaptation in comparison with the first-year students of the Medical and Preventive Faculty.Conclusion: the immune system indicators responsible for the processes of primary immune response are reduced in military medical students comparing with medical students, which in its turn forms possible prerequisites for the development of clinical manifestations of immune dysfunction. The period of psychological adaptation to the educational process in a medical university is less successful for first-year students of the Military Training Centre. It is necessary to develop measures aimed at increasing the sense of responsibility, psychoemotional and immune adaptation resources.

Published
2023
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10. The BM@N spectrometer at the NICA accelerator complex

Author

Afanasiev, S., Agakishiev, G., Aleksandrov, E., Aleksandrov, I., Alekseev, P., Alishina, K., Astakhov, V., Atkin, E., Aushev, T., Azorskiy, V., Babkin, V., Balashov, N., Barak, R., Baranov, A., Baranov, D., Baranova, N., Barbashina, N., Baznat, M., Bazylev, S., Belov, M., Blau, D., Bocharnikov, V., Bogdanova, G., Bolozdynya, A., Bondar, E., Boos, E., Buryakov, M., Buzin, S., Chebotov, A., Chemezov, D., Chen, J.H., Demanov, A., Dementev, D., Dmitriev, A., Drnoyan, J., Dryablov, D., Dryuk, A., Dubinchik, B., Dulov, P., Egorov, A., Egorov, D., Elsha, V., Fediunin, A., Fedosimova, A., Filippov, I., Filozova, I., Finogeev, D., Gabdrakhmanov, I., Galavanov, A., Gavrischuk, O., Gertsenberger, K., Golosov, O., Golovatyuk, V., Grigoriev, P., Golubeva, M., Guber, F., Ibraimova, S., Idrisov, D., Idrissova, T., Iusupova, A., Ivashkin, A., Izvestnyy, A., Kabadzhov, V., Kanokova, Sh., Kapishin, M., Kapitonov, I., Karjavin, V., Karmanov, D., Karpushkin, N., Kattabekov, R., Kekelidze, V., Khabarov, S., Kharlamov, P., Khudaiberdyev, G., Khukhaeva, A., Khvorostukhin, A., Kiryushin, Yu., Klimai, P., Kolesnikov, V., Kolozhvari, A., Kopylov, Yu., Korolev, M., Kovachev, L., Kovalev, I., Kruglova, I., Kovalev, Yu., Kozlov, I., Kozlov, V., Kuklin, S., Kulish, E., Kurganov, A., Kutergina, V., Kuznetsov, A., Ladygin, E., Lanskoy, D., Lashmanov, N., Lebedev, I., Lenivenko, V., Lednicky, R., Leontiev, V., Lyapin, D., Litvinenko, E., Ma, Y.G., Makankin, A., Makhnev, A., Malakhov, A., Mamaev, M., Martemianov, A., Martovitsky, E., Mashitsin, K., Merkin, M., Merts, S., Morozov, S., Murin, Yu., Musaev, K., Musulmanbekov, G., Myasnikov, A., Myktybekov, D., Nagdasev, R., Nemnyugin, S., Nikitin, D., Novozhilov, S., Olimov, Kh., Olimov, K., Palichik, V., Parfenov, P., Pelevanyuk, I., Peresunko, D., Piyadin, S., Platonova, M., Plotnikov, V., Podgainy, D., Pukhaeva, N., Ratnikov, F., Reshetova, S., Rogov, V., Romanov, I., Rufanov, I., Rukoyatkin, P., Rumyantsev, M., Rybakov, T., Sakulin, D., Sedykh, S., Serebryakov, D., Shabanov, A., Segal, I., Semak, A., Sergeev, S., Serikkanov, A., Sheremetev, A., Sheremeteva, A., Shchipunov, A., Shitenkov, M., Shopova, M., Shumikhin, V., Shutov, A., Shutov, V., Shodmonov, M., Slepnev, I., Slepnev, V., Slepov, I., Smirnov, A., Smolyanin, T., Solomin, A., Sorin, A., Sosnovtsev, V., Spaskov, V., Stavinskiy, A., Stekhanov, V., Stepanenko, Yu., Streletskaya, E., Streltsova, O., Strikhanov, M., Sukhov, E., Suvarieva, D., Taer, G., Taranenko, A., Tarasov, N., Tarasov, O., Teremkov, P., Terletsky, A., Teryaev, O., Tcholakov, V., Tikhomirov, V., Timoshenko, A., Tojiboev, O., Topilin, N., Tretyakova, T., Troshin, V., Truttse, A., Tserruya, I., Tskhay, V., Tyapkin, I., Ustinov, V., Vasendina, V., Velichkov, V., Volkov, V., Voronin, A., Voytishin, N., Yuldashev, B., Yurevich, V., Zamiatin, N., Zavertyaev, M., Zhang, S., Zhavoronkova, I., Zhezher, V., Zhigareva, N., Zinchenko, A., Zubankov, A., Zubarev, E., and Zuev, M.

Published
2024
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11. Unperturbed inverse kinematics nucleon knockout measurements with a 48 GeV/c carbon beam

Author

Patsyuk, M., Kahlbow, J., Laskaris, G., Duer, M., Lenivenko, V., Segarra, E. P., Atovullaev, T., Johansson, G., Aumann, T., Corsi, A., Hen, O., Kapishin, M., Panin, V., Piasetzky, E., Abraamyan, Kh., Afanasiev, S., Agakishiev, G., Alekseev, P., Atkin, E., Aushev, T., Babkin, V., Balandin, V., Baranov, D., Barbashina, N., Batyuk, P., Bazylev, S., Beck, A., Bertulani, C. A., Blaschke, D., Blau, D., Bogoslovsky, D., Bolozdynya, A., Boretzky, K., Burtsev, V., Buryakov, M., Buzin, S., Chebotov, A., Chen, J., Ciszewski, A., Cruz-Torres, R., Dabrowska, B., Dmitriev, D. Dabrowski A., Dryablov, A., Dulov, P., Egorov, D., Fediunin, A., Filippov, I., Filippov, K., Finogeev, D., Gabdrakhmanov, I., Galavanov, A., Gasparic, I., Gavrischuk, O., Gertsenberger, K., Gillibert, A., Golovatyuk, V., Golubeva, M., Guber, F., Ivanova, Yu., Ivashkin, A., Izvestnyy, A., Kakurin, S., Karjavin, V., Karpushkin, N., Kattabekov, R., Kekelidze, V., Khabarov, S., Kiryushin, Yu., Kisiel, A., Kolesnikov, V., Kolozhvari, A., Kopylov, Yu., Korover, I., Kovachev, L., Kovalenko, A., Kovalev, Yu., Kugler, A., Kuklin, S., Kulish, E., Kuznetsov, A., Ladygin, E., Lashmanov, N., Litvinenko, E., Lobastov, S., Loher, B., Ma, Y. -G., Makankin, A., Maksymchyuk, A., Malakhov, A., Mardor, I., Merts, S., Morozov, A., Morozov, S., Musulmanbekov, G., Nagdasev, R., Nikitin, D., Palchik, V., Peresunko, D., Peryt, M., Petukhov, O., Petukhov, Yu., Piyadin, S., Plotnikov, V., Pokatashkin, G., Potrebenikov, Yu., Rogachevsky, O., Rogov, V., Roslon, K., Rossi, D., Rufanov, I., Rukoyatkin, P., Rumyantsev, M., Sakulin, D., Samsonov, V., Scheit, H., Schmidt, A., Sedykh, S., Selyuzhenkov, I., Senger, P., Sergeev, S., Shchipunov, A., Sheremeteva, A., Shitenkov, M., Shumikhin, V., Shutov, A., Shutov, V., Simon, H., Slepnev, I., Slepnev, V., Slepov, I., Sorin, A., Sosnovtsev, V., Spaskov, V., Starecki, T., Stavinskiy, A., Streletskaya, E., Streltsova, O., Strikhanov, M., Sukhov, N., Suvarieva, D., Tanaka, J., Taranenko, A., Tarasov, N., Tarasov, O., Tarasov, V., Terletsky, A., Teryaev, O., Tcholakov, V., Tikhomirov, V., Timoshenko, A., Topilin, N., Topko, B., Tornqvist, H., Tyapkin, I., Vasendina, V., Vishnevsky, A., Voytishin, N., Wagner, V., Warmusz, O., Yaron, I., Yurevich, V., Zamiatin, N., Zhang, Song, Zherebtsova, E., Zhezher, V., Zhigareva, N., Zinchenko, A., Zubarev, E., and Zuev, M.

Subjects
Nuclear Experiment, Nuclear Theory
Abstract

From superconductors to atomic nuclei, strongly-interacting many-body systems are ubiquitous in nature. Measuring the microscopic structure of such systems is a formidable challenge, often met by particle knockout scattering experiments. While such measurements are fundamental for mapping the structure of atomic nuclei, their interpretation is often challenged by quantum mechanical initial- and final-state interactions (ISI/FSI) of the incoming and scattered particles. Here we overcome this fundamental limitation by measuring the quasi-free scattering of 48 GeV/c 12C ions from hydrogen. The distribution of single protons is studied by detecting two protons at large angles in coincidence with an intact 11B nucleus. The 11B detection is shown to select the transparent part of the reaction and exclude the otherwise large ISI/FSI that would break the 11B apart. By further detecting residual 10B and 10Be nuclei, we also identified short-range correlated (SRC) nucleon-nucleon pairs, and provide direct experimental evidence for the separation of the pair wave-function from that of the residual many-body nuclear system. All measured reactions are well described by theoretical calculations that do not contain ISI/FSI distortions. Our results thus showcase a new ability to study the short-distance structure of short-lived radioactive atomic nuclei at the forthcoming FAIR and FRIB facilities. These studies will be pivotal for developing a ground-breaking microscopic understanding of the structure and properties of nuclei far from stability and the formation of visible matter in the universe., Comment: Accepted for publication in Nature Physics. 28 pages, 19 figures, and 1 table including main text, Methods, and Supplementary materials

Published
2021
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13. Clinical and immunological characteristics of medical students depending on the duration and program of study

Author

S. A. Chebotov, R. T. Urazmambetov, I. I. Andreeva, and M. V. Kharitonova

Subjects
psycho-emotional stress, adaptation, students, natural killers, immune dysregulation, stress-forming factors, Immunologic diseases. Allergy, RC581-607
Abstract

Chronic psycho-emotional stress can cause dysfunction of neuroimmunoendocrine dysregulation with consequences in the form of a violation of the functional potential of the immune system. Adaptation to new living conditions at the start of studies at a medical university is one of the inevitable circumstances that first-year students overcome. Education under the military training program at a medical university carries an additional stress load in this aspect. Research on the mechanisms of formation of adaptive reactions of the immune system during training under the military training program for officers of the medical service is of undoubted interest. The purpose of the study was to compare the clinical manifestations of immune-mediated pathology and the parameters of adaptive and innate immunity of medical students depending on the length of service and training program. Under observation were 104 medical students, all men, of which 37 were first-year students and 67 were third-year students of a medical university. The subjects of each course were divided into two subgroups depending on the training program. The group of first-year students consisted of 18 people from the military training center (VTC) and 19 people from the medical and preventive faculty (LPF). Among the third-year students of the VUC – 31, LPF – 36. For the clinical characterization of the incidence during the year of study, registration cards for the analysis of immune-mediated pathology were used, the parameters of the immune system at the end of the spring semester were studied using standard methodological approaches. The data obtained indicate that in the first year students with an additional load in the form of a military training program have a more difficult time adapting to learning in comparison with first-year students of the medical faculty. These differences consist in a more frequent and significant clinical manifestation of infectious pathology and are reflected in the functional potential of cellular parameters of innate immunity. The statement of signs of inhibition of the functional potencies of macrophage cells and natural killers in firstyear students of a military training center is an alarming factor in the possible disruption of the adaptive reserves of the immune response system, which probably suggests the need to develop programs to prevent the negative impact of stress-forming factors. By the third year of study, the students of the military training center have the best clinical and immunological indicators of the functioning of the immune system in comparison with the students of the standard educational program of general practitioners. It is likely that during this period the process of psychological adaptation of military medical students is completed.

Published
2023
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14. Determination of Phobic Disorders Using Virtual Reality Technologies

Author

Obukhov, Artem, Dedov, Denis, Chebotov, Nikita, Nazarova, Alexandra, Teselkin, Daniil, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, and Silhavy, Radek, editor

Published
2022
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17. Characteristics of the parameters of the innate and acquired immune response during the period of adaptation to training at a Medical University

Author

L. P. Sizyakina, I. I. Andreeva, R. T. Urazmambetov, and S. A. Chebotov

Subjects
adaptation, innate immunity, acquired immunity, training, medical university, medical students, Immunologic diseases. Allergy, RC581-607
Abstract

Adaptation for new social conditions is an inevitable factor which the first-year students undergo when entering a medical school. Immune system as a part of entire structural and functional homeostatic complex, is involved into the adaptive reactions, thus pointing to its participation in fitting the new lifestyle among first-year students. One should note some peculiarities of immune reactions which depend on the organization pattern of educational process: despite common features of studies, the training environment for beginners at the military training center (VTC) is different from those for students at the medical and preventive faculty (LPF). The purpose of our study was to compare quantitative and functional parameters of immune system in the first-year students at a medical university, depending on distinct features of educational arrangement.The study included 36 first-year students of the Medical University divided into two groups, comparable for age, sex, and physical condition. The first group included 18 first-year VUTS students, whereas the second group consisted of 18 LPF pupils. Studies of immunological parameters in peripheral blood were carried out three months after the training was started. We have assessed counts and functional potential of T cells, their subpopulation profile, B lymphocyte counts, and serum level of IgA, IgM and IgG, total numbers of natural killer cells and proportion of cytolytically active forms, oxygen-producing activity of neutrophils, and the numbers of peripheral monocytes expressing type 2,4 Toll-like receptors (TLR). Comparison of the adaptive immune response parameters did not reveal any gross differences between the groups. At the same time, evaluation of markers reflecting functional potential of innate immunity cells revealed distinct signs of immune reactions, depending on the faculty of the first-year students. It has been shown that the proportion of functionally active NK-cells containing lytic granzyme B granules was lower in the EUTC students. Also, military medical students have a statistically significantly lower relative and absolute number of peripheral blood monocytes expressing surface TLR 4. The detected signs of suppressed functional potential of macrophages and natural killer cells in the first-year OUV students represent the possibly alarming factor of impaired adaptive reserves of immune system. The data obtained are of interest for development of immune rehabilitation programs to prevent clinical manifestations of immune dysfunction.

Published
2021
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24. Information Systems for Online and Offline Data Processing in Modern High-Energy Physics Experiments

Author

Evgeny Alexandrov, Igor Alexandrov, Konstantin Gertsenberger, Mikhail Mineev, Andrey Moshkin, Darya Pryahina, Irina Filozova, Alexandr Chebotov, Galina Shestakova, and Alexander Yakovlev

Subjects
nica megaproject, nica accelerator-accumulator complex, lhc experiments, online and offline data processing, data acquisition system (daq), information system (is), database (db), Electronic computers. Computer science, QA75.5-76.95
Abstract

Acquiring, storing, processing and analyzing of experimental and simulated data are an integral part of high-energy physics experiments. Data Acquisition system (DAQ) is responsible for solving these problems in modern experiments. The review is devoted to the study of the general functioning systems for data collecting and processing, information systems and databases, which are used in high-energy physics experiments, their classification, and the possibility and necessity of creating similar systems or individual components in experiments of the NICA (Nuclotron-based Ion Collider fAcility) megaproject both on a fixed target and in the collider part. Such systems being used to support for data processing and analysis, as well as other types of experiment activities, significantly contribute to solving the problem of automating the collection, storage, processing and analysis of experimental data and information on the experiment, and they are also an essential element for the successful operation of modern high-energy physics experiments.Particular attention in the analysis of the solutions is given to physics experiments on particle collisions at the Large Hadron Collider (LHC) at the European Center for Nuclear Research (CERN) as successful modern projects that are constantly upgraded due to changes in the functioning of the systems (for example, increasing beam energy and luminosity) and improving the information systems taking into account the latest technologies in this area. As a result of the study, systems and components are chosen, whose implementation or adaptation is most appropriate to the experiments of the NICA complex.

Published
2019
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26. Features of human capillary blood flow on breathing by heated helio-oxygen mixtures

Author

A. V. Stroy, D. V. Pukhnyak, A. A. Tanova, and S. A. Chebotov

Abstract

The purpose of the study: to assess the features of microcirculatory blood flow.Materials and methods. A comparative assessment of microcirculation by laser Doppler flowmetry was carried out in 19 male volunteers aged 20–25 years against the background of breathing heated to 40° C oxygen-nitrogen and helium-oxygen gas mixtures.Main results. Breathing with a heated oxygen-nitrogen mixture consisted in an increase (by approximately 25–35%) of the values of the integral indicator of microcirculation against the background of a decrease in its efficiency. Switching to breathing with a heated helium-oxygen mixture «HeliOx 25/75» in all examined persons also led to an increase in the volumetric velocity of the peripheral blood flow. However, the degree of increase in the indicator (by 35–45% compared with normal breathing conditions) turned out to be significantly more pronounced than it was during breathing with a heated oxygen-nitrogen mixture. In addition, when breathing «HeliOx 25/75», starting from about the 2nd minute of breathing, an increase in the efficiency of microcirculation was observed due to an increase in the «contribution» to the blood flow reaction of its «active» (neuromyogenic) components.

Published
2022
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29. Characteristics of the parameters of the innate and acquired immune response during the period of adaptation to training at a Medical University

Author

I. I. Andreeva, L. P. Sizyakina, S. A. Chebotov, and R. T. Urazmambetov

Subjects
medicine.medical_specialty, training, business.industry, Period (gene), Immunology, Training (meteorology), medical students, adaptation, RC581-607, acquired immunity, Physical medicine and rehabilitation, medical university, Acquired immune response, Immunology and Allergy, Medicine, Immunologic diseases. Allergy, Adaptation (computer science), business, innate immunity
Abstract

Adaptation for new social conditions is an inevitable factor which the first-year students undergo when entering a medical school. Immune system as a part of entire structural and functional homeostatic complex, is involved into the adaptive reactions, thus pointing to its participation in fitting the new lifestyle among first-year students. One should note some peculiarities of immune reactions which depend on the organization pattern of educational process: despite common features of studies, the training environment for beginners at the military training center (VTC) is different from those for students at the medical and preventive faculty (LPF). The purpose of our study was to compare quantitative and functional parameters of immune system in the first-year students at a medical university, depending on distinct features of educational arrangement.The study included 36 first-year students of the Medical University divided into two groups, comparable for age, sex, and physical condition. The first group included 18 first-year VUTS students, whereas the second group consisted of 18 LPF pupils. Studies of immunological parameters in peripheral blood were carried out three months after the training was started. We have assessed counts and functional potential of T cells, their subpopulation profile, B lymphocyte counts, and serum level of IgA, IgM and IgG, total numbers of natural killer cells and proportion of cytolytically active forms, oxygen-producing activity of neutrophils, and the numbers of peripheral monocytes expressing type 2,4 Toll-like receptors (TLR). Comparison of the adaptive immune response parameters did not reveal any gross differences between the groups. At the same time, evaluation of markers reflecting functional potential of innate immunity cells revealed distinct signs of immune reactions, depending on the faculty of the first-year students. It has been shown that the proportion of functionally active NK-cells containing lytic granzyme B granules was lower in the EUTC students. Also, military medical students have a statistically significantly lower relative and absolute number of peripheral blood monocytes expressing surface TLR 4. The detected signs of suppressed functional potential of macrophages and natural killer cells in the first-year OUV students represent the possibly alarming factor of impaired adaptive reserves of immune system. The data obtained are of interest for development of immune rehabilitation programs to prevent clinical manifestations of immune dysfunction.

Published
2021
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30. Software Development for the BM@N Experiment at NICA: Challenges and Status

Author

Gertsenberger Konstantin, Merts Sergey, Gabdrakhmanov Ilnur, Filozova Irina, Alexandrov Igor, Alexandrov Evgeny, Moshkin Andrey, and Chebotov Alexander

Subjects
Physics, QC1-999
Abstract

A new generation of experiments on relativistic nuclear physics is planned to be started in the nearest years at the Nuclotron-based Ion Collider facility (NICA) under construction at the Joint Institute for Nuclear Research in Dubna. The fixed target experiment BM@N (Baryonic Matter at Nuclotron) is considered as a first stage towards the implementation of the physics program available at NICA. For a successful accomplishment of the BM@N physics program, a well-developed and tested software package for simulation, digitization, reconstruction and analysis of collision events and other supporting tasks is of utmost importance. The data flow scheme of the experiment is shown. Offine and online software systems, such as the main BmnRoot framework, databases of the experiment, data monitoring and others providing information support for the experiment are presented. The implementation of the software systems is a necessary stage for the successful operation of the BM@N experiment.

Published
2020
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34. Configuration Information System for online processing and data monitoring in the NICA experiments

Author

E. Alexandrov, I. Alexandrov, A. Chebotov, K. Gertsenberger, I. Filozova, D. Priakhina, and G. Shestakova

Subjects
History, Computer Science Applications, Education
Abstract

The collection, storage and processing of experimental data are an integral part of modern high-energy physics experiments. The Configuration Information System (CIS) based on the Configuration Database (ConfigDb) is an essential element of a complex of information systems developed for the NICA experiments. The CIS is used to store and provide data on the configuration of the experiment hardware and software systems when collecting data from the detectors in online mode. The ConfigDb stores both a set of various configuration parameters and descriptions of a sequence of online software tasks to be started and run during experiment sessions. The system allows loading configuration information, activating hardware setups and launching all necessary software applications with the required parameters on the specified distributed nodes. The CIS architecture mainly contains the ConfigDb and Configuration Manager, which uses the Dynamic Deployment System API for managing tasks and providing intercommunication. The manager loads configuration data from the database, starts software tasks in a described sequence and supports task process management. The client-server architecture of the CIS is presented. The client has been implemented as a Web service to manage configuration parameters by users.

Published
2023
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35. Implementation of the Event Metadata System for physics analysis in the NICA experiments

Author

E Alexandrov, I Alexandrov, A Chebotov, A Degtyarev, I Filozova, K Gertsenberger, P Klimai, and A Yakovlev

Subjects
History, Computer Science Applications, Education
Abstract

NICA (Nuclotron-based Ion Collider fAcility) is a new accelerator complex, which is under construction at the Joint Institute for Nuclear Research in Dubna to study properties of dense baryonic matter. The experiments of the NICA projects have already generated and obtained substantial volumes of event data, and it is expected that the overall number of stored events will increase from the current value of hundreds of millions to several billion events per year. The developed Event Metadata System is required to store and index experimental event records obtained at NICA facilities, allowing to quickly search for only necessary events based on various criteria for further processing and physics analyses. The main aim of the information system that is described is to speed up desired physics analyses and data quality checks. In addition, it allows reducing the load of the NICA computing infrastructure. The Event Metadata System, which is presented in the paper, is integrated with other experimental and software systems, in particular, NICA ROOT-based frameworks and implemented Condition Database. An access and management of the event metadata in the Event Catalogue being used to select only events for a particular physics analysis are provided via several interfaces, such as REST API, Web UI, and a dedicated C++/ROOT interface. The detailed architecture of the system and developed services including monitoring are also presented.

Published
2023
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38. The Development of a Virtual Installation Visualization Training System for Oil and Gas Industry

Author

N. N. Prokudina, N. A. Chebotov, K. I. Patutin, A. D. Obukhov, and N. A. Vekhteva

Subjects
Engineering, Petroleum industry, business.industry, Training system, business, Manufacturing engineering, Visualization
Abstract

In the context of the need to implement distance education and improve the quality of educational materials, an urgent problem is the development of modern means of representing knowledge and mastering the necessary competencies for students. As such means, it is possible to use virtual laboratory stands and installations that implement in three-dimensional space processes and objects corresponding to real equipment and production. This correspondence allows, using modern information technologies, to organize the educational process in a virtual space on various devices due to the cross-platform property of the Unity development environment. The paper presents the process of developing a visualization system using the example of a virtual installation for training specialists in the oil and gas industry. The structure of the system, used tools, software implementation is considered. The proposed approaches can be used to develop a wide range of virtual stands and installations.

Published
2020
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41. Electronic Logbook platform for NICA experiments

Author

Ivan P. Slepov, Konstantin Gertsenberger, Alexander I. Chebotov, and Andrey Anatolevich Moshkin

Subjects
Set (abstract data type), Software deployment, Process (engineering), Real-time computing, Experimental data, Web service, Raw data, computer.software_genre, Logbook, computer, Task (project management)
Abstract

The acquisition of experimental data is an integral part of all modern high-energy physics experiments. This task is of particular importance in the experiments of the NICA project, which is currently under construction at the Joint Institute for Nuclear Research, due to the high interaction rate of heavy ion collision events and the complexity of detector systems. During experiments sessions, not only the collected experimental data are important, but also parameters and conditions under which the experiments are conducted. To record and store all the information, the shift crew needs a structured and systematized online electronic journal. The article presents a new implementation of the Online Logbook System designed to automate the latter process for the NICA experiments. The Logbook System allows collaboration members to record information during experiment runs on current events, operation conditions of the detectors and their parameters, which are further used in raw data processing, reconstruction and physics analysis of the particle collision events in the experiments. A new version of the Electronic Logbook has been implemented as a configurable platform to be used in different experiments on particle collisions, such as a fixed target BM@N and collider MPD and SPD experiments of the NICA project. In addition, the specialized API and user Web service developed for viewing, changing and searching for the required logbook data, as well as a set of auxiliary services and a common deployment system are considered.

Published
2021
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42. Unperturbed inverse kinematics nucleon knockout measurements with a carbon beam

Author

S. Morozov, T. Atovullaev, O. Gavrischuk, I. Rufanov, D. M. Rossi, I. Slepnev, V. Tcholakov, V. Zhezher, Yu. Potrebenikov, E.P. Segarra, A. Timoshenko, A. Taranenko, A. Corsi, A. Shutov, D. Blaschke, A. Terletsky, G. Musulmanbekov, A. Kuznetsov, A. Vishnevsky, Herbert A. Simon, V. Vasendina, E. Piasetzky, V. Lenivenko, R. Kattabekov, D. Sakulin, A. Dmitriev, S. Lobastov, P. Dulov, Yu. Ivanova, O. Warmusz, N. Topilin, V. Rogov, M. Duer, P. Senger, V. Spaskov, D. Suvarieva, A. Morozov, Alexander Schmidt, N. Lashmanov, Kh. U. Abraamyan, I. Slepov, K. Gertsenberger, N. Zamiatin, D. Baranov, M. Strikhanov, V. Yurevich, K. Boretzky, V. Babkin, V. Samsonov, G. Agakishiev, N. Karpushkin, D. Bogoslovsky, V. Kekelidze, D. Peresunko, Y.-G. Ma, I. Filippov, A. Ciszewski, A. Ivashkin, D. Egorov, B. Topko, A. Zinchenko, M. Patsyuk, V. Shumikhin, V. Plotnikov, O. Petukhov, S. Bazylev, V. Shutov, Carlos A. Bertulani, M. Buryakov, A. Fediunin, V. Tikhomirov, E. Litvinenko, A. Makankin, I. Korover, D. Blau, S. Khabarov, Yu. Kiryushin, S. Piyadin, A. Stavinskiy, V. Kolesnikov, D. Finogeev, A. Kovalenko, M. Golubeva, M. Kapishin, A. Chebotov, D. Nikitin, A. Dryablov, J. Tanaka, Oleg B. Tarasov, Igor Gašparić, S. Kakurin, Or Hen, J. Kahlbow, F. Guber, Yu. Kopylov, O. Teryaev, V. Wagner, I. Selyuzhenkov, A. Malakhov, O. Streltsova, A. Kolozhvari, V. Burtsev, P. Alekseev, M. Rumyantsev, H. Törnqvist, E. Zherebtsova, S. Sedykh, P. Rukoyatkin, I. Gabdrakhmanov, A. Bolozdynya, A. Kugler, M. Shitenkov, N. Barbashina, N. Zhigareva, A. Izvestnyy, Yu. Kovalev, S. Kuklin, K. Roslon, N. Tarasov, O. Rogachevsky, A. Galavanov, S. Merts, Thomas Aumann, B. Dabrowska, V. Palchik, L. Kovachev, E. Atkin, R. Nagdasev, A. Maksymchyuk, V. Golovatyuk, N. Sukhov, J. Chen, G. Laskaris, E. Zubarev, V. Slepnev, T. Aushev, A. Sorin, B. Löher, S. Sergeev, V. Panin, V. Karjavin, A. Sheremeteva, E. Kulish, V. Sosnovtsev, G. Pokatashkin, G. Johansson, S. Buzin, K. Filippov, E. Streletskaya, M. Peryt, I. Mardor, Yu.P. Petukhov, V. Tarasov, H. Scheit, M. Zuev, P. Batyuk, V. Balandin, A. Shchipunov, I. Yaron, E. Ladygin, Song Zhang, D. Dabrowski, R. Cruz-Torres, A. Beck, T. Starecki, N. Voytishin, I. Tyapkin, A. Kisiel, and S. Afanasiev

Subjects
Physics, Hydrogen, Isotope, Scattering, Nuclear Theory, General Physics and Astronomy, chemistry.chemical_element, nuclear structure, experiments with inverse kinematics, quasi-free scattering, short-range correlations, 01 natural sciences, 010305 fluids & plasmas, Ion, Nuclear physics, chemistry, 0103 physical sciences, Particle, Facility for Antiproton and Ion Research, 010306 general physics, Nucleon, Wave function, Nuclear Experiment
Abstract

Particle knockout scattering experiments1,2 are fundamental for mapping the structure of atomic nuclei2–6, but their interpretation is often complicated by initial- and final-state interactions of the incoming and scattered particles1,2,7–9. Such interactions lead to reduction in the scattered particle flux and distort their kinematics. Here we overcome this limitation by measuring the quasi-free scattering of 48 GeV c–1 12C ions from hydrogen. The distribution of single protons is studied by detecting two protons at large angles in coincidence with an intact 11B nucleus. The 11B detection suppresses the otherwise large distortions of reconstructed single-proton distributions induced by initial- and final-state interactions. By further detecting residual 10B and 10Be nuclei, we also identified short-range correlated nucleon–nucleon pairs9–13 and provide direct experimental evidence for separation of the pair wavefunction from that of the residual many-body nuclear system9,14. All measured reactions are well described by theoretical calculations that include no distortions from the initial- and final-state interactions. Our results showcase the ability to study the short-distance structure of short-lived radioactive nuclei at the forthcoming Facility for Antiproton and Ion Research (FAIR)15 and Facility for Rare Isotope Beams (FRIB)16 facilities, which is relevant for understanding the structure and properties of nuclei far from stability and the formation of visible matter in the Universe. Initial- and final-state interactions distort the kinematics in particle knockout scattering experiments, complicating their interpretation. These effects are suppressed by detecting 11B nuclei in quasi-free scattering of 12C ions from hydrogen.

Published
2021

43. Ecosystem of information services for the BM@N experiment

Author

Alexander I. Chebotov, Konstantin Gertsenberger, and Ivan P. Slepov

Subjects
Service (business), World Wide Web, Integrated services, Computer science, Information system, Entry point, User interface, Security policy, Logbook, Visualization
Abstract

The report describes all the web services that compose information service ecosystem of the BM@N experiment and details of their implementation. The following integrated services are presented, such as a Single Authorization and Group Security Policy service, system for storing structured information on the experiment, online Electronic Logbook system, collaboration forum, service for visualization hardware parameters of the slow control system, user interface for the offline database of the experiment and job definition service for distributed data processing. The main entry point for collaboration members is the official BM@N website, from which access to all the implemented information services is obtained.

Published
2021
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49. Mathematical Modeling of a Virtual Platform for Training Specialists in the Oil and Gas Industry

Author

N Prokudina, D Davydova, K Patutin, and N Chebotov

Subjects
History, Engineering, Petroleum industry, business.industry, business, Virtual platform, Training (civil), Manufacturing engineering, Computer Science Applications, Education
Abstract

A relevant task in the organization of comprehensive training of specialists in various fields is the development of the necessary theoretical and practical competencies. In the conditions of pandemic restrictions and the need to conduct classes in a distance mode, there is a need to develop new educational resources and means of representing knowledge, functioning on the basis of modern information technologies. One of the promising approaches is the transfer of laboratory and practical exercises to a virtual platform that allows you to master the necessary practical competencies on a computer. However, the functioning and visualization of physical or chemical processes in such virtual platforms must correspond to real processes. The article discusses the mathematical modeling of a virtual platform for training specialists in the oil and gas industry. An approach to the construction of a mathematical model based on the collected experimental data, the study of the laws of equilibrium of liquid and gas, and hydrostatic equations is considered. On the basis of the obtained model, an algorithm for the functioning of a virtual stand on the Unity platform is built. The presented approach can be used in the implementation of various virtual platforms for organizing the learning process in a distance form.

Published
2021
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50. Software Development for the BM@N Experiment at NICA: Challenges and Status

Author

Konstantin Gertsenberger, Alexander I. Chebotov, Andrey Anatolevich Moshkin, Ilnur R. Gabdrakhmanov, I. Alexandrov, Evgeny Alexandrov, S. Merts, and I. Filozova

Subjects
Scheme (programming language), Nuclotron, 010308 nuclear & particles physics, business.industry, Physics, QC1-999, Software development, 01 natural sciences, law.invention, Data flow diagram, law, 0103 physical sciences, Systems engineering, Data monitoring, Software system, 010306 general physics, business, Collider, computer, Digitization, computer.programming_language
Abstract

A new generation of experiments on relativistic nuclear physics is planned to be started in the nearest years at the Nuclotron-based Ion Collider facility (NICA) under construction at the Joint Institute for Nuclear Research in Dubna. The fixed target experiment BM@N (Baryonic Matter at Nuclotron) is considered as a first stage towards the implementation of the physics program available at NICA. For a successful accomplishment of the BM@N physics program, a well-developed and tested software package for simulation, digitization, reconstruction and analysis of collision events and other supporting tasks is of utmost importance. The data flow scheme of the experiment is shown. Offine and online software systems, such as the main BmnRoot framework, databases of the experiment, data monitoring and others providing information support for the experiment are presented. The implementation of the software systems is a necessary stage for the successful operation of the BM@N experiment.

Published
2020

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