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17 results on '"Chebat, Enrica"'

2. Dapagliflozin acutely improves kidney function in type 2 diabetes mellitus. The PRECARE study

Author

Lazzaroni, Elisa, Lunati, Maria Elena, Montefusco, Laura, Pastore, Ida, Chebat, Enrica, Cimino, Vincenzo, Morpurgo, Paola Silvia, Muratori, Milena, Plebani, Laura, Bolla, Andrea, Rossi, Antonio, Vallone, Luciana, Gandolfi, Alessandra, Tinari, Camilla, D’Addio, Francesca, Nasr, Moufida Ben, Loretelli, Cristian, Scaranna, Cristiana, Bellante, Rosalia, Manfrini, Roberto, Muratori, Fabrizio, Franzetti, Ivano, Orsi, Emanuela, Gazzaruso, Carmine, Ghelardi, Renata, Desenzani, Paolo, Genovese, Stefano, Girelli, Angela, Folli, Franco, Berra, Cesare, and Fiorina, Paolo

Published
2022
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3. Acute and long-term disruption of glycometabolic control after SARS-CoV-2 infection

Author

Montefusco, Laura, Ben Nasr, Moufida, D’Addio, Francesca, Loretelli, Cristian, Rossi, Antonio, Pastore, Ida, Daniele, Giuseppe, Abdelsalam, Ahmed, Maestroni, Anna, Dell’Acqua, Marco, Ippolito, Elio, Assi, Emma, Usuelli, Vera, Seelam, Andy Joe, Fiorina, Roberta Maria, Chebat, Enrica, Morpurgo, Paola, Lunati, Maria Elena, Bolla, Andrea Mario, Finzi, Giovanna, Abdi, Reza, Bonventre, Joseph V., Rusconi, Stefano, Riva, Agostino, Corradi, Domenico, Santus, Pierachille, Nebuloni, Manuela, Folli, Franco, Zuccotti, Gian Vincenzo, Galli, Massimo, and Fiorina, Paolo

Published
2021
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4. Immunogenicity and Safety of SARS-CoV-2 mRNA Vaccines in a Cohort of Patients With Type 1 Diabetes

Author

D’Addio, Francesca, primary, Sabiu, Gianmarco, additional, Usuelli, Vera, additional, Assi, Emma, additional, Abdelsalam, Ahmed, additional, Maestroni, Anna, additional, Seelam, Andy Joe, additional, Ben Nasr, Moufida, additional, Loretelli, Cristian, additional, Mileto, Davide, additional, Rossi, Giada, additional, Pastore, Ida, additional, Montefusco, Laura, additional, Morpurgo, Paola S., additional, Plebani, Laura, additional, Rossi, Antonio, additional, Chebat, Enrica, additional, Bolla, Andrea M., additional, Lunati, Maria Elena, additional, Mameli, Chiara, additional, Macedoni, Maddalena, additional, Antinori, Spinello, additional, Rusconi, Stefano, additional, Gallieni, Maurizio, additional, Berra, Cesare, additional, Folli, Franco, additional, Galli, Massimo, additional, Gismondo, Maria Rita, additional, Zuccotti, Gianvincenzo, additional, and Fiorina, Paolo, additional

Published
2022
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5. Indirect and Direct Effects of SARS-CoV-2 on Human Pancreatic Islets

Author

Nasr, Moufida Ben, primary, D’Addio, Francesca, primary, Montefusco, Laura, primary, Usuelli, Vera, primary, Loretelli, Cristian, primary, Rossi, Antonio, primary, Pastore, Ida, primary, Abdelsalam, Ahmed, primary, Maestroni, Anna, primary, Dell’Acqua, Marco, primary, Ippolito, Elio, primary, Assi, Emma, primary, Seelam, Andy Joe, primary, Fiorina, Roberta Maria, primary, Chebat, Enrica, primary, Morpurgo, Paola, primary, Lunati, Maria Elena, primary, Bolla, Andrea Mario, primary, Abdi, Reza, primary, Bonventre, Joseph V., primary, Rusconi, Stefano, primary, Riva, Agostino, primary, Corradi, Domenico, primary, Santus, Pierachille, primary, Clark, Pamela, primary, Nebuloni, Manuela, primary, Baldi, Gabriella, primary, Finzi, Giovanna, primary, Folli, Franco, primary, Zuccotti, Gian Vincenzo, primary, Galli, Massimo, primary, Herold, Kevan C., primary, and Fiorina, Paolo, primary

Published
2022
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6. Indirect and Direct Effects of SARS-CoV-2 on Human Pancreatic Islets

Author

Ben Nasr, Moufida, primary, D’Addio, Francesca, additional, Montefusco, Laura, additional, Usuelli, Vera, additional, Loretelli, Cristian, additional, Rossi, Antonio, additional, Pastore, Ida, additional, Abdelsalam, Ahmed, additional, Maestroni, Anna, additional, Dell’Acqua, Marco, additional, Ippolito, Elio, additional, Assi, Emma, additional, Seelam, Andy Joe, additional, Fiorina, Roberta Maria, additional, Chebat, Enrica, additional, Morpurgo, Paola, additional, Lunati, Maria Elena, additional, Bolla, Andrea Mario, additional, Abdi, Reza, additional, Bonventre, Joseph V., additional, Rusconi, Stefano, additional, Riva, Agostino, additional, Corradi, Domenico, additional, Santus, Pierachille, additional, Clark, Pamela, additional, Nebuloni, Manuela, additional, Baldi, Gabriella, additional, Finzi, Giovanna, additional, Folli, Franco, additional, Zuccotti, Gian Vincenzo, additional, Galli, Massimo, additional, Herold, Kevan C., additional, and Fiorina, Paolo, additional

Published
2022
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7. Immunogenicity and safety of SARS-CoV-2 mRNA vaccines in a cohort of patients with type 1 diabetes.

Author

D'Addio, Francesca, Sabiu, Gianmarco, Usuelli, Vera, Assi, Emma, Abdelsalam, Ahmed, Maestroni, Anna, Seelam, Andy Joe, Ben Nasr, Moufida, Loretelli, Cristian, Mileto, Davide, Rossi, Giada, Pastore, Ida, Montefusco, Laura, Morpurgo, Paola S., Plebani, Laura, Rossi, Antonio, Chebat, Enrica, Bolla, Andrea M., Lunati, Maria Elena, and Mameli, Chiara

Abstract

Patients with type 1 diabetes (T1D) may develop severe outcomes during COVID-19 disease, but their ability to generate an immune response against the SARS-CoV-2 messenger RNA (mRNA) vaccines remains to be established. Here we evaluated the safety, immunogenicity and glycometabolic effects of the SARS-CoV-2 mRNA vaccines in patients with T1D. A total of 375 patients, 326 with T1D and 49 non-diabetics, who received two doses of the SARS-CoV-2 mRNA vaccines (mRNA-1273, BNT162b2) between March and April 2021 at the ASST FBF-Sacco Milan, Italy, were included in this monocentric observational study (NCT04905823). Local and systemic adverse events were reported in both groups after SARS-CoV-2 mRNA vaccination without statistical differences between them. While both T1D patients and non-diabetic subjects exhibited a parallel increase in anti-SARS-CoV-2S titers after vaccination, the vast majority of T1D patients (70% and 78% respectively) did not show any increase in the SARS-CoV-2-specific cytotoxic response as compared to the robust increased observed in all non-diabetic subjects. A reduced secretion of the T cell-related cytokines IL-2 and TNF-alpha in vaccinated patients with T1D was also observed. No glycometabolic alterations were evident in patients with T1D using continuous glucose monitoring during follow-up. Administration of the SARS-CoV-2 mRNA vaccine is associated with an impaired cellular SARS-CoV-2-specific cytotoxic immune response in T1D patients. [ABSTRACT FROM AUTHOR]

Published
2022
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10. Atrial natriuretic peptide in multiple system atrophy

Author

Bevilacqua, Maurizio, Norbiato, Guido, Righini, Velella, Castelli, Lucia, Rogolino, Angela, Furlan, Raffaello, Piazza, Simona, Chebat, Enrica, and Vago, Tarcisio

Subjects
Neuromuscular diseases -- Physiological aspects, Natriuretic peptides -- Physiological aspects, Hypothalamus -- Physiological aspects, Biological sciences
Abstract

The effects of hypertonic and isotonic saline solution on atrial natriuretic peptide (ANP) and the role of ANP on blood pressure and volume control were analyzed in patients with type A and type B multiple system atrophy (MSA). MSA patients with peripheral sympathetic efferent denervation and preserved afferent control of vasopressin exhibited normal ANP-related hemodynamic and osmolar activities. However, MSA patients without sinoaortic afferent control of circulation exhibited impaired ANP activities.

Published
1996

11. Metabolic effects of fluvastatin extended release 80 mg and atorvastatin 20 mg in patients with type 2 diabetes mellitus and low serum high-density lipoprotein cholesterol levels: a 4-month, prospective, open-label, randomized, blinded—end point (probe) trial

Author

Bevilacqua, Maurizio, primary, Guazzini, Barbara, additional, Righini, Velella, additional, Barrella, Massimo, additional, Toscano, Rosanna, additional, and Chebat, Enrica, additional

Published
2004
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16. βAdrenergic Receptors and Reflex Tachycardia After Single and Repeated Felodipine Administration in Essential Hypertension

Author

Savonitto, Stefano, Bevilacqua, Maurizio, Chebat, Enrica, Vago, Tarcisio, Bertora, Pierluigi, Baldi, Gabriella, Renesto, Elio, Peruzzi, Elena, Sardina, Marco, and Norbiato, Guido

Abstract

To verify the possible contribution of β-adrenergic receptor down-regulation to the reversal of reflex tachycardia during chronic treatment with a dihydropyridine calcium antagonist. 11 hypertensive patients were studied with noninvasive blood pressure (BP) and heart rate (HR) monitoring after a placebo period, and on the first and seventh day of felodipine administration. 5 mg twice daily. Plasma catecholamines and neutrophil β-adrenergic receptors were measured on the first and seventh day of treatment, immediately before and 2 h after drug administration. The first administration of felodipine was followed by a significant drop in BP (peakreduction in mean BP 24 $$ 7 mm Hg). lasting 6 h and mirrored by reflex tachycardia (peak increase in HR 14 $$ 9 beats/min). On the mornin go the seventh day. 12 gafter the previous felodipine administration, mean BP (MBP) was 16 mm Hg lower than on the last placebo day. while HR was unchanged. The next administration of felodipine was followed by a smaller drop in BP (MBP – 15 $$ 7 mm Hg; NS vs. placebo), while reflex tachycardia was the same as after acute felodipine (HR 13 $$ 8 beats/min; p < 0.05 vs. placebo. NS vs. acute administration). Plasma noradrenaline concentration increased after both acute and chronic administration (p < 0.0001), and preadministration values were highest on day 7 (p < 0.05). Neutrophil β-adrenergic receptor density and affinity did not change either acutely or chronically. This study gives both indirect and direct evidence that β-adrenoceptor down-regulation does not occur during repeated felodipine administration in hypertension. Reflex tachycardia is not abolished, but is reset to lower BP levels

Published
1991

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