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2. Stoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort

Author

Greijdanus, Nynke G., Wienholts, Kiedo, Ubels, Sander, Talboom, Kevin, Hannink, Gerjon, Wolthuis, Albert, de Lacy, Francisco B., Lefevre, Jérémie H., Solomon, Michael, Frasson, Matteo, Rotholtz, Nicolas, Denost, Quentin, Perez, Rodrigo O., Konishi, Tsuyoshi, Panis, Yves, Rutegård, Martin, Hompes, Roel, Rosman, Camiel, van Workum, Frans, Tanis, Pieter J., de Wilt, Johannes H.W., Bremers, Andreas J.A., Ferenschild, Floris T., de Vriendt, Stefanie, D’Hoore, André, Bislenghi, Gabriele, Farguell, Jordi, Lacy, Antonio M., Atienza, Paula González, van Kessel, Charlotte S., Parc, Yann, Voron, Thibault, Collard, Maxime K., Muriel, Jorge Sancho, Cholewa, Hannia, Mattioni, Laura A., Frontali, Alice, Polle, Sebastiaan W., Polat, Fatih, Obihara, Ndidi J., Vailati, Bruna B., Kusters, Miranda, Tuynmann, Jurriaan B., Hazen, Sanne J.A., Grüter, Alexander A.J., Amano, Takahiro, Fujiwara, Hajime, Salomon, Mario, Ruiz, Hernán, Gonzalez, Ricardo, Estefanía, Diego, Avellaneda, Nicolas, Carrie, Augusto, Santillan, Mateo, Pantoja Pachajoa, Diana A., Parodi, Matias, Gielis, Manuel, Binder, Alf-Dorian, Gürtler, Thomas, Riedl, Peter, Badiani, Sarit, Berney, Christophe, Morgan, Matthew, Hollington, Paul, da Silva, Nigel, Nair, Gavin, Ho, Yiu M., Lamparelli, Michael, Kapadia, Raj, Kroon, Hidde M., Dudi-Venkata, Nagendra N., Liu, Jianliang, Sammour, Tarik, Flamey, Nicolas, Pattyn, Paul, Chaoui, Ahmed, Vansteenbrugge, Louis, van den Broek, Nathalie E.J., Vanclooster, Patrick, de Gheldere, Charles, Pletinckx, Pieter, Defoort, Barbara, Dewulf, Maxime, Slavchev, Mihail, Belev, Nikolay, Atanasov, Boyko, Krastev, Panche, Sokolov, Manol, Maslyankov, Svilen, Gribnev, Petar, Pavlov, Vasil, Ivanov, Tsvetomir, Karamanliev, Martin, Filipov, Emil, Tonchev, Pencho, Aigner, Felix, Mitteregger, Martin, Allmer, Caterina, Seitinger, Gerald, Colucci, Nicola, Buchs, Nicolas, Ris, Frédéric, Toso, Christian, Gialamas, Eleftherios, Vuagniaux, Aurélie, Chautems, Roland, Sauvain, Marc-Olivier, Daester, Silvio, von Flüe, Markus, Guenin, Marc-Olivier, Taha-Mehlitz, Stephanie, Hess, Gabriel F., Martínek, Lubomír, Skrovina, Matej, Machackova, Maria, Benčurik, Vladimir, Uluk, Deniz, Pratschke, Johann, Dittrich, Luca S., Guel-Klein, Safak, Perez, Daniel, Grass, Julia-Kristin, Melling, Nathaniel, Mueller, Simone, Iversen, Lene H., Eriksen, Jacob D., Baatrup, Gunnar, Al-Najami, Issam, Bjørsum-Meyer, Thomas, Teras, Jüri, Teras, Roland M., Monib, Fatma A., Abu Elnga Ahmed, Nagm Eldin, Alkady, Eithar, Ali, Ahmed K., Khedr, Gehan Abd Elatti, Abdelaal, Ahmed Samir, Bassyouni Ashoush, Fouad M., Ewedah, Moataz, Elshennawy, Eslam M., Hussein, Mohamed, Fernández-Martínez, Daniel, García-Flórez, Luis J., Fernández-Hevia, María, Suárez-Sánchez, Aida, del Hoyo Aretxabala, Izaskun, Docampo, Iria Losada, Zabala, Jesús Gómez, Tejedor, Patricia, Morales Bernaldo de Quirós, Javier T., Quiroga, Ignacio Bodega, Navarro-Sánchez, Antonio, Darias, Iván Soto, Fernández, Cristina López, de La Cruz Cuadrado, Cristina, Sánchez-Guillén, Luis, López-Rodríguez-Arias, Francisco, Soler-Silva, Álvaro, Arroyo, Antonio, Bernal-Sprekelsen, Juan C., Gómez-Abril, Segundo Á., Gonzálvez, Paula, Torres, María T., Sánchez, Teresa Rubio, Antona, Francisco Blanco, Sánchez Lara, Juan E., Alcázar Montero, José A., Fernández-Martínez, Daniel, García-Flórez, Luis J., Fernández-Hevia, María, Suárez-Sánchez, Aida, Colás-Ruiz, Enrique, Tasende-Presedo, Marta M., Fernández-Hurtado, Ignacio, Cifuentes-Ródenas, José A., Suárez, Marta Castro, Losada, Manuel, Hernández, Miguel, Alonso, Alfredo, Diéguez, Beatriz, Serralta, Daniel, Medina Quintana, Rita E., Gil Lopez, Jose M., Pinto, Francisca Lima, Nieto-Moreno, Elena, Bonito, Alba Correa, Santacruz, Carlos Cerdán, Marcos, Elena Bermejo, Septiem, Javier García, Calero-Lillo, Aránzazu, Alanez-Saavedra, Javier, Muñoz-Collado, Salvador, López-Lara, Manuel, Martínez, María Labalde, Herrero, Eduardo Ferrero, Borda, Francisco Javier García, Villar, Óscar García, Escartín, Jorge, Blas, Juan L., Ferrer, Rocío, Egea, Jorge García, Rodríguez-Infante, Antonio, Mínguez-Ruiz, Germán, Carreño-Villarreal, Guillermo, Pire-Abaitua, Gerardo, Dziakova, Jana, Rodríguez, Carlos Sáez-Cazallas, Pizarro Aranda, María J., Muguerza Huguet, José M., Borda-Arrizabalaga, Nerea, Enriquez-Navascués, José M., Echaniz, Garazi Elorza, Ansorena, Yolanda Saralegui, Estaire-Gómez, Mercedes, Martínez-Pinedo, Carlos, Barbero-Valenzuela, Alejandro, Ruíz-García, Pablo, Kraft, Miquel, Gómez-Jurado, María J., Pellino, Gianluca, Espín-Basany, Eloy, Cotte, Eddy, Panel, Nathalie, Goutard, Claire-Angéline, deÁngelis, Nicola, Lauka, Lelde, Shaikh, Shafaque, Osborne, Laura, Ramsay, George, Nichita, Vladimir-Ion, Bhandari, Santosh, Sarmah, Panchali, Bethune, Rob M., Pringle, Heather C.M., Massey, Lisa, Fowler, George E., Hamid, Hytham K.S., de Simone, Belinda D., Kynaston, James, Bradley, Nicholas, Stienstra, Roxane M., Gurjar, Shashank, Mukherjee, Tanmoy, Chandio, Ashfaq, Ahmed, Safia, Singh, Baljit, Runau, Francois, Chaudhri, Sanjay, Siaw, Oliver, Sarveswaran, Janahan, Miu, Victor, Ashmore, Daniel, Darwich, Haitham, Singh-Ranger, Deepak, Singh, Nirbhaibir, Shaban, Mohamed, Gareb, Fahed, Petropolou, Thalia, Polydorou, Adreas, Dattani, Mit, Afzal, Asma, Bavikatte, Akshay, Sebastian, Boby, Ward, Nicholas, Mishra, Amitabh, Manatakis, Dimitrios, Agalianos, Christos, Tasis, Nikolaos, Antonopoulou, Maria-Ioanna, Karavokyros, Ioannis, Charalabopoulos, Alexandros, Schizas, Dimitrios, Baili, Efstratia, Syllaios, Athanasios, Karydakis, Lysandros, Vailas, Michail, Balalis, Dimitrios, Korkolis, Dimitrios, Plastiras, Aris, Rompou, Aliki, Xenaki, Sofia, Xynos, Evangelos, Chrysos, Emmanuel, Venianaki, Maria, Christodoulidis, Grigorios, Perivoliotis, Konstantinos, Tzovaras, George, Baloyiannis, Ioannis, Ho, Man-Fung, Ng, Simon Siu-man, Mak, Tony Wing-chung, Futaba, Kaori, Šantak, Goran, Šimleša, Damir, osić, Jurica, Zukanović, Goran, Kelly, Michael E., Larkin, John O., McCormick, Paul H., Mehigan, Brian J., Connelly, Tara M., Neary, Peter, Ryan, Jessica, McCullough, Peter, Al-Juaifari, Maytham A., Hammoodi, Hayder, Abbood, Ali Hashim, Calabrò, Marcello, Muratore, Andrea, Terra, Antonio La, Farnesi, Francesca, Feo, Carlo V., Fabbri, Nicolò, Pesce, Antonio, Fazzin, Marta, Roscio, Francesco, Clerici, Federico, Lucchi, Andrea, Vittori, Laura, Agostinelli, Laura, Ripoli, Maria Cristina, Sambucci, Daniele, Porta, Andrea, Sinibaldi, Giovanni, Crescentini, Giacomo, larcinese, Antonella, Picone, Emanuele, Persiani, Roberto, Biondi, Alberto, Pezzuto, Roberto, Lorenzon, Laura, Rizzo, Gianluca, Coco, Claudio, D’Agostino, Luca, Spinelli, Antonino, Sacchi, Matteo M., Carvello, Michele, Foppa, Caterina, Spinelli, Antonino, Sacchi, Matteo M., Carvello, Michele, Foppa, Caterina, Maroli, Annalisa, Palini, Gian M., Garulli, Gianluca, Zanini, Nicola, Delrio, Paolo, Rega, Daniela, Carbone, Fabio, Aversano, Alessia, Pirozzolo, Giovanni, Recordare, Alfonso, DʼAlimonte, Lucrezia, Vignotto, Chiara, Corbellini, Carlo, Sampietro, Gianluca M., Lorusso, Leonardo, Manzo, Carlo A., Ghignone, Federico, Ugolini, Giampaolo, Montroni, Isacco, Pasini, Franceso, Pasini, Francesco, Ballabio, Michele, Bisagni, Pietro, Armao, Francesca T., Longhi, Marco, Ghazouani, Omar, Galleano, Raffaele, Tamini, Nicolò, Oldani, Massimo, Nespoli, Luca, Picciariello, Arcangelo, Altomare, Donato F., Tomasicchio, Giovanni, Lantone, Giuliano, Catena, Fausto, Giuffrida, Mario, Annicchiarico, Alfredo, Perrone, Gennaro, Grossi, Ugo, Santoro, Giulio A., Zanus, Giacomo, Iacomino, Alessandro, Novello, Simone, Passuello, Nicola, Zucchella, Martino, Puca, Lucia, deGiuli, Maurizio, Reddavid, Rossella, Scabini, Stefano, Aprile, Alessandra, Soriero, Domenico, Fioravanti, Emanuela, Rottoli, Matteo, Romano, Angela, Tanzanu, Marta, Belvedere, Angela, Mariani, Nicolò M., Ceretti, Andrea P., Opocher, Enrico, Gallo, Gaetano, Sammarco, Giuseppe, de Paola, Gilda, Pucciarelli, Salvatore, Marchegiani, Francesco, Spolverato, Gaya, Buzzi, Gianluca, Di Saverio, Salomone, Meroni, Paola, Parise, Cristiano, Bottazzoli, Elisa I., Lapolla, Pierfrancesco, Brachini, Gioia, Cirillo, Bruno, Mingoli, Andrea, Sica, Giuseppe, Siragusa, Leandro, Bellato, Vittoria, Cerbo, Daniele, de Pasqual, Carlo A., de Manzoni, Giovanni, di Cosmo, Maria A., Alrayes, Bourhan M.H., Qandeel, Mahmoud W. M., Hani, Mohammad Bani, Rabadi, Alexander, el Muhtaseb, Mohammad S., Abdeen, Basel, Karmi, Fahed, Žilinskas, Justas, Latkauskas, Tadas, Tamelis, Algimantas, Pikūnienė, Ingrida, Šlenfuktas, Vygintas, Poskus, Tomas, Kryzauskas, Marius, Jakubauskas, Matas, Mikalauskas, Saulius, Jakubauskiene, Lina, Hassan, Soha Y., Altrabulsi, Amani, Abdulwahed, Eman, Ghmagh, Reem, Deeknah, Abdulqudus, Alshareea, Entisar, Elhadi, Muhammed, Abujamra, Saleh, Msherghi, Ahmed A., Tababa, Osama W.E., Majbar, Mohammed A., Souadka, Amine, Benkabbou, Amine, Mohsine, Raouf, Echiguer, Sabrillah, Moctezuma-Velázquez, Paulina, Salgado-Nesme, Noel, Vergara-Fernández, Omar, Sainz-Hernández, Juan C., Alvarez-Bautista, Francisco E., Zakaria, Andee D., Zakaria, Zaidi, Wong, Michael P.K., Ismail, Razif, Ibrahim, Aini F., Abdullah, Nik A.N., Julaihi, Rokayah, Bhat, Sameer, OʼGrady, Greg, Bissett, Ian, Lamme, Bas, Musters, Gijsbert D., Dinaux, Anne M., Grotenhuis, Brechtje A., Steller Arend G.J. Aalbers, Ernst J., Leeuwenburgh, Marjolein M., Rutten, Harm J.T., Burger, Jacobus W.A., Bloemen, Johanne G., Ketelaers, Stijn H.J., Waqar, Usama, Chawla, Tabish, Rauf, Hareem, Rani, Pallavi, Talsma, Aaldert K., Scheurink, Lieke, van Praagh, Jasper B., Segelman, Josefin, Nygren, Jonas, Anderin, Kajsa, Tiefenthal, Marit, de Andrés, Beatriz, Beltrán de Heredia, Juan P., Vázquez, Andrea, Gómez, Tania, Golshani, Parisa, Kader, Rawaz, Mohamed, Abudi, Westerterp, Marinke, Marinelli, Andreas, Niemer, Quirine, Doornebosch, Pascal G., Shapiro, Joël, Vermaas, Maarten, de Graaf, Eelco J.R., van Westreenen, Hendrik L., Zwakman, Marije, van Dalsen, Annette D., Vles, Wouter J., Nonner, Joost, Toorenvliet, Boudewijn R., Janssen, Paul T.J., Verdaasdonk, Emiel G.G., Amelung, Femke J., Peeters Renu R. Bahadoer, Koen C.M.J., Holman, Fabian A., Heemskerk, Jeroen, Vosbeek, Noortje, Leijtens, Jeroen W.A., Taverne, Sophie B.M., Heijnen, Bob H.M., El-Massoudi, Youssef, de Groot-van Veen, Irene, Hoff, Christiaan, Jou-Valencia, Daniela, Consten, Esther C.J., Burghgraef, Thijs A., Geitenbeek, Ritch, Hulshof, Lorenzo G.W.L., Slooter, Gerrit D., Reudink, Muriël, Bouvy, Nicole D., Wildeboer, Aurelia C. L., Verstappen, Sonja, Pennings, Alexander J., van den Hengel, Berber, Wijma, Allard G., de Haan, Jael, de Nes, Lindsey C.F., Heesink, Vera, Karsten, Tom, Heidsma, Charlotte M., Koemans, Willem J., Dekker, Jan-Willem T., van der Zijden, Charlène J., Roos, Daphne, Demirkiran, Ahmet, van der Burg, Sjirk, Oosterling, Steven J., Hoogteijling, Tijs J., Wiering, Bastiaan, Smeeing, Diederik P.J., Havenga, Klaas, Lutfi, Hamid, Consten, Esther C.J., Tsimogiannis, Konstantinos, Sköldberg, Filip, Folkesson, Joakim, den Boer, Frank, van Schaik, Ted G., van Gerven, Pieter, Sietses, Colin, Hol, Jeroen C., Boerma, Evert-Jan G., Creemers, Davy M.J., Schultz, Johannes K., Frivold, Tone, Riis, Rolf, Gregussen, Hilde, Busund, Sondre, Sjo, Ole H., Gaard, Maria, Krohn, Nina, Ersryd, Amanda L., Leung, Edmund, Waqar, Usama, Chawla, Tabish, Rauf, Hareem, Rani, Pallavi, Sultan, Hytham, Hajjaj, Baraa Nabil, Alhisi, Ahmed Jehad, Khader, Ahmed A.E., Mendes, Ana Filipa Dias, Semião, Miguel, Faria, Luis Queiroz, Azevedo, Constança, da Costa Devesa, Helena M., Martins, Sónia Fortuna, Rodrigues Jarimba, Aldo M., Ribeiro Marques, Sónia M., Ferreira, Rita Marques, Oliveira, António, Ferreira, Cátia, Pereira, Ricardo, Surlin, Valeriu M., Graure, Giorgiana M., Ramboiu, Stefan Patrascu Sandu D., Negoi, Ionut, Ciubotaru, Cezar, Stoica, Bogdan, Tanase, Ioan, Stoica, Bogdan, Ciubotaru, Cezar, Negoita, Valentina M., Florea, Sabrina, Macau, Florin, Vasile, Mihai, Stefanescu, Victor, Dimofte, Gabriel-Mihail, Luncă, Sorinel, Roată, Cristian-Ene, Mu[Latin Small Letter s with comma below]ină, Ana-Maria, Garmanova, Tatiana, Agapov, Mikhail N., Markaryan, Daniil G., Eduard, Galliamov, Yanishev, Alexey, Abelevich, Alexander, Bazaev, Andrey, Rodimov, Sergey V., Filimonov, Victor B., Melnikov, Andrey A., Suchkov, Igor A., Drozdov, EvgeniyS., Kostromitskiy, Dmitriy N., Sjöström, Olle, Matthiessen, Peter, Baban, Bayar, Gadan, Soran, Jadid, Kaveh Dehlaghi, Staffan, Maria, Park, Jennifer M., Rydbeck, Daniel, Lydrup, Marie-Louise, Buchwald, Pamela, Jutesten, Henrik, Darlin, Lotten, Lindqvist, Ebba, Nilsson, Karl, Larsson, Per-Anders, Jangmalm, Staffan, Košir, Jurij A., Tomažič, Aleš, Grosek, Jan, Božič, Tajda Košir, Zazo, Aya, Zazo, Rama, Fares, Hala, Ayoub, Kusay, Niazi, Ammar, Mansour, Ali, Abbas, Ayman, Tantoura, Mohammad, Hamdan, Alaa, Hassan, Naya, Hasan, Bassam, Saad, Ahmad, Sebai, Amine, Haddad, Anis, Maghrebi, Houcine, Kacem, Montasser, Yalkın, Ömer, Samsa, Mehmet Veysi, Atak, İbrahim, Balci, Bengi, Haberal, Elifcan, Dogan, Lütfi, Gecim, Ibrahim E., Akyol, Cihangir, Koc, Mehmet A., Sivrikoz, Emre, Piyadeoğlu, Deniz, Larkin, John O., avanagh, Dara O., Sökmen, Selman, Bişgin, Tayfun, Günenç, Erşan, Güzel, Melek, Leventoğlu, Sezai, Yüksel, Osman, Kozan, Ramazan, Göbüt, Hüseyin, Cengiz, Fevzi, Erdinc, Kemal, Acar, Nihan Coşgun, Kamer, Erdinc, Özgür, İlker, Aydın, Oguzhan, Keskin, Metin, Bulut, Mehmet Türker, Kulle, Cemil B., Kara, Yasin, Sıbıç, Osman, Özata, İbrahim H., Buğra, Dursun, Balık, Emre, Kulle, Cemil B., Çakır, Murat, Alhardan, Anas, Colak, Elif, CiftciEngin Aybar, Ahmet B., Sari, Ahmet Can, Atici, Semra Demirli, Kaya, Tayfun, Dursun, Ayberk, Calik, Bulent, Özkan, Ömer Faruk, Ülgür, Hanife Şeyda, Düzgün, Özgül, Monson, John, George, Sarah, Woods, Kayla, Al-Eryani, Fatima, Albakry, Rudaina, Coetzee, Emile, Boutall, Adam, Herman, Ayesiga, Warden, Claire, Mugla, Naser, Forgan, Tim, Mia, Imraan, and Lambrechts, Anton

Published
2023
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3. Cumulative 5-year Results of a Randomized Controlled Trial Comparing Biological Mesh With Primary Perineal Wound Closure After Extralevator Abdominoperineal Resection (BIOPEX-study)

Author

Blok, Robin D., Sharabiany, Sarah, Stoker, Jaap, Laan, Ellen T. M., Bosker, Robbert J. I., Burger, Jacobus W. A., Chaudhri, Sanjay, van Duijvendijk, Peter, van Etten, Boudewijn, van Geloven, Anna A. W., de Graaf, Eelco J. R., Hoff, Christiaan, Hompes, Roel, Leijtens, Jeroen W. A., Rothbarth, Joost, Rutten, Harm J. T., Singh, Baljit, Vuylsteke, Ronald J. C. L. M., de Wilt, Johannes H. W., Dijkgraaf, Marcel G. W., Bemelman, Willem A., Musters, Gijsbert D., and Tanis, Pieter J.

Published
2022
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7. Perineal wound closure using gluteal turnover flap or primary closure after abdominoperineal resection for rectal cancer: study protocol of a randomised controlled multicentre trial (BIOPEX-2 study)

Author

Sharabiany, Sarah, Blok, Robin D., Lapid, Oren, Hompes, Roel, Bemelman, Wilhelmus A., Alberts, Victor P., Lamme, Bas, Wijsman, Jan H., Tuynman, Jurriaan B., Aalbers, Arend G. J., Beets, Geerard L., Fabry, Hans F. J., Cherepanin, Ivan M., Polat, Fatih, Burger, Jacobus W. A., Rutten, Harm J. T., Bosker, Robert J. I., Talsma, Koen, Rothbarth, Joost, Verhoef, Cees, van de Ven, Anthony W. H., van der Bilt, Jarmila D. W., de Graaf, Eelco J. R., Doornebosch, Pascal G., Leijtens, Jeroen W. A., Heemskerk, Jeroen, Singh, Baljit, Chaudhri, Sanjay, Gerhards, Michael F., Karsten, Tom M., de Wilt, Johannes H. W., Bremers, Andre J. A., Vuylsteke, Ronald J. C. L. M., Heuff, Gijsbert, van Geloven, Anna A. W., Tanis, Pieter J., and Musters, Gijsbert D.

Published
2020
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9. An international survey exploring the management of pilonidal disease.

Author

Gallo, Gaetano, Goglia, Marta, Senapati, Asha, Pata, Francesco, Basso, Luigi, Grossi, Ugo, El‐Hussuna, Alaa, Blackwell, Sue, Buchs, Nicolas C., Chaudhri, Sanjay, Dardanov, Dragomir, Dulskas, Audrius, Frasson, Matteo, Glasbey, James, Keatley, James, Kelly, Michael E., Li, Elizabeth, Minaya‐Bravo, Ana Maria, Morton, Dion, and Neary, Peter

Subjects
DISEASE management, OPERATIVE surgery, PUBLIC hospitals, FREE flaps, MINIMALLY invasive procedures, THERAPEUTICS
Abstract

Aim: Pilonidal disease (PD) is a common debilitating condition frequently seen in surgical practice. Several available treatments carry different benefit/risk balances. The aim of this study was to snapshot the current management of PD across European countries. Method: Members affiliated to the European Society of Coloproctology were invited to join the survey. An invitation was extended to others via social media. The predictive power of respondents' and hospitals' demographics on the change of therapeutic approach was explored. Results: Respondents (n = 452) were mostly men (77%), aged 26–60 years, practising in both academic and public hospitals and with fair distribution between colorectal (51%) and general (48%) surgeons. A total of 331 (73%) respondents recommended surgery at first presentation of the disease. Up to 80% of them recommended antibiotic therapy and 95% did not use any classification of PD. A primary closure technique was the preferred procedure (29%), followed by open technique (22%), flap creation (7%), sinusectomy (7%) and marsupialization (7%). Approximately 27% of subjects would choose the same surgical technique even after a failure. Almost half (46%) perform surgery as office based. A conservative approach was negatively associated with acutely presenting PD (p < 0.001). Respondents who were not considering tailored surgery based on patient presentation tended to change their approach in the case of a failed procedure. Conclusion: With the caveat of a heterogeneous number of respondents across countries, the results of our snapshot survey may inform the development of future guidelines. [ABSTRACT FROM AUTHOR]

Published
2023
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12. The 2022 European Society of Coloproctology (ESCP) global snapshot audit of faecal incontinence: Study protocol.

Author

Dulskas, Audrius, El‐Hussuna, Alaa, Makunaite, Gabija, van Ramshorst, Gabrielle, Gallo, Gaetano, Pellino, Gianluca, Glasbey, James, Dardanov, Dragomir, Svagzdys, Saulius, Knowles, Charlie, Bravo, Ana Minaya, Singh, Baljit, Li, Elizabeth, Sivrikoz, Emre, Negoi, Ionut, Pinkney, Thomas, Neary, Peter, Chaudhri, Sanjay, Frasson, Matteo, and Pata, Francesco

Subjects
FECAL incontinence, RESEARCH protocols, SURGICAL clinics, HOSPITAL patients, DATABASES
Abstract

Aim: Faecal incontinence (FI) is a common problem, affecting about 9% of Western populations. However, only a few patients seek consultation and the number of such patients reaching hospital care is unknown. Current treatment pathways are poorly evidence based and are thought to vary greatly between different countries. This audit will study the incidence of patients presenting to coloproctologists with FI, current practice including diagnostics, conservative and surgical techniques across different units in Europe and worldwide. The aim is to explore the incidence of FI in patients attending colorectal surgical clinics, treatment choices and accessibility to diagnostic tools/advanced treatments across the international cohort. Outcomes to be measured include the volume of FI patients consulting clinical practice per surgeon, patient demographics, and diagnostics and intervention details. Method: An international multicentre snapshot audit will be performed. During the study period all consecutive eligible patients will be included over an 8‐week period between 9 January and 28 February. Data will be entered and saved in a Research Electronic Data Capture secured database. Moreover, two short physician and centre‐level surveys will be filled for current practice evaluation. The results will be published in international journals and will be prepared in accordance with guidelines set by the STROBE (strengthening the reporting of observational studies in epidemiology) statement for observational studies. Discussion: This multicentre, global prospective audit will be delivered by consultant colorectal and general surgeons as well as trainees. The data obtained will lead to a better understanding of the incidence of FI and treatment and diagnostic possibilities. This snapshot audit will be hypothesis generating and inform areas that need future prospective study. [ABSTRACT FROM AUTHOR]

Published
2023
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13. An international assessment of surgeon practices in abdominal wound closure and surgical site infection prevention by the European Society for Coloproctology.

Author

Chowdhury, Sharfuddin, El‐Hussuna, Alaa, Gallo, Gaetano, Keatley, James, Kelly, Michael E., Minaya‐Bravo, Ana, Ovington, Liza, Pata, Francesco, Pellino, Gianluca, Pinkney, Thomas, Sanchez Guillen, Luis, Schmitz, Niels‐Derrek, Spychaj, Kerstin, Riess, Celine, van Ramshorst, Gabrielle H., Blackwell, Sue, Buchs, Nicolas C., Chaudhri, Sanjay, Dardanov, Dragomir, and Dulskas, Audrius

Subjects
SURGICAL site infections, INFECTION prevention, ASEPSIS & antisepsis, SURGICAL site, SURGEONS, ABDOMINAL wall
Abstract

Aim: The burden of abdominal wound failure can be profound. Recent clinical guidelines have highlighted the heterogeneity of laparotomy closure techniques. The aim of this study was to investigate current midline closure techniques and practices for prevention of surgical site infection (SSI). Method: An online survey was distributed in 2021 among the membership of the European Society of Coloproctology and its partner societies. Surgeons were asked to provide information on how they would close the abdominal wall in three specific clinical scenarios and on SSI prevention practices. Results: A total of 561 consultants and trainee surgeons participated in the survey, mainly from Europe (n = 375, 66.8%). Of these, 60.6% identified themselves as colorectal surgeons and 39.4% as general surgeons. The majority used polydioxanone for fascial closure, with small bite techniques predominating in clean‐contaminated cases (74.5%, n = 418). No significant differences were found between consultants and trainee surgeons. For SSI prevention, more surgeons preferred the use of mechanical bowel preparation (MBP) alone over MBP and oral antibiotics combined. Most surgeons preferred 2% alcoholic chlorhexidine (68.4%) or aqueous povidone‐iodine (61.1%) for skin preparation. The majority did not use triclosan‐coated sutures (73.3%) or preoperative warming of the wound site (78.5%), irrespective of level of training or European/non‐European practice. Conclusion: Abdominal wound closure technique and SSI prevention strategies vary widely between surgeons. There is little evidence of a risk‐stratified approach to wound closure materials or techniques, with most surgeons using the same strategy for all patient scenarios. Harmonization of practice and the limitation of outlying techniques might result in better outcomes for patients and provide a stable platform for the introduction and evaluation of further potential improvements. [ABSTRACT FROM AUTHOR]

Published
2023
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21. Minimally invasive right colectomy anastomosis study (MIRCAST):Protocol for an observational cohort study of surgical complications using four surgical techniques for anastomosis in patients with a right colon tumor

Author

Gomez Ruiz, Marcos, Bianchi, Paolo Pietro, Chaudhri, Sanjay, Gerjy, Roger, Gögenur, Ismail, Jayne, David, Khan, Jim S., Rautio, Tero, Sánchez-Guillén, Luis, Spinoglio, Giuseppe, Ulrich, Alexis, Rouanet, Philippe, Gomez Ruiz, Marcos, Bianchi, Paolo Pietro, Chaudhri, Sanjay, Gerjy, Roger, Gögenur, Ismail, Jayne, David, Khan, Jim S., Rautio, Tero, Sánchez-Guillén, Luis, Spinoglio, Giuseppe, Ulrich, Alexis, and Rouanet, Philippe

Abstract

Background: Right colectomy is the standard surgical treatment for tumors in the right colon and surgical complications are reduced with minimally-invasive laparoscopy compared with open surgery, with potential further benefits achieved with robotic assistance. The anastomotic technique used can also have an impact on patient outcomes. However, there are no large, prospective studies that have compared all techniques. Methods/design: MIRCAST is the Minimally-Invasive Right Colectomy Anastomosis Study that will compare laparoscopy with robot-assisted surgery, using either intracorporeal or extracorporeal anastomosis, in a large prospective, observational, multicenter, parallel, four-cohort study in patients with a benign or malignant, non-metastatic tumor of the right colon. Over 2 years of follow-up, the study will prospectively evaluate peri- and postoperative complications, postoperative recovery, hospital stay, and mid-term results including survival, local recurrence, metastases rate, and conversion rate. The primary composite endpoint will be the efficacy of the surgical method regarding surgical wound infections and postoperative complications (Clavien-Dindo grade III-IV complications at 30 days post-surgery). Secondary endpoints include long-term oncologic results, conversion rate, operative time, length of stay, and quality of life. Discussion: This will be the first large, international study to prospectively evaluate the use of minimally-invasive laparoscopy or robot-assisted surgery during right hemicolectomy and to control for the impact of the anastomotic technique. The research will contribute to current knowledge regarding the medical care of patients with malignant or benign tumors of the right colon, and enable physicians to determine which technique may be the most appropriate for their patients. Trial registration: This study was registered on Clinicaltrials.gov (clinicaltrials.gov identifier: NCT03650517) on August 28th 2018 (study protocol ve

Published
2020

23. Cumulative 5-year Results of a Randomized Controlled Trial Comparing Biological Mesh With Primary Perineal Wound Closure After Extralevator Abdominoperineal Resection (BIOPEX-study)

Author

Blok, Robin D., primary, Sharabiany, Sarah, additional, Stoker, Jaap, additional, Laan, Ellen T. M., additional, Bosker, Robbert J. I., additional, Burger, Jacobus W. A., additional, Chaudhri, Sanjay, additional, van Duijvendijk, Peter, additional, van Etten, Boudewijn, additional, van Geloven, Anna A. W., additional, de Graaf, Eelco J. R., additional, Hoff, Christiaan, additional, Hompes, Roel, additional, Leijtens, Jeroen W. A., additional, Rothbarth, Joost, additional, Rutten, Harm J. T., additional, Singh, Baljit, additional, Vuylsteke, Ronald J. C. L. M., additional, de Wilt, Johannes H. W., additional, Dijkgraaf, Marcel G. W., additional, Bemelman, Willem A., additional, Musters, Gijsbert D., additional, and Tanis, Pieter J., additional

Published
2021
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24. Prophylactic biological mesh reinforcement versus standard closure of stoma site (ROCSS): a multicentre, randomised controlled trial

Author

Bhangu, Aneel, primary, Nepogodiev, Dmitri, additional, Ives, Natalie, additional, Magill, Laura, additional, Glasbey, James, additional, Forde, Colm, additional, Bisgaard, Thue, additional, Handley, Kelly, additional, Mehta, Samir, additional, Morton, Dion, additional, Pinkney, Thomas, additional, Bhangu, Aneel, additional, Brown, James, additional, Futaba, Kaori, additional, Khan, Sarah, additional, Pallan, Arvind, additional, Patel, Abhilasha, additional, Ashdown-Phillips, Steve, additional, Roberts, Tracy, additional, Jowett, Susan, additional, Munetsi, Lorraine, additional, Torrance, Andrew, additional, Hilken, Nicholas, additional, Hill, Matt, additional, Hunter, Mark, additional, Leek, Susan, additional, Lilly, Helen, additional, Sawant, Amruta, additional, Vince, Alexandra, additional, Walters, Michael, additional, Bemelman, Willem, additional, Blussé, Marjolein, additional, Borstlap, Wernard, additional, Busch, Olivier RC, additional, Buskens, Christianne, additional, Klaver, Charlotte, additional, Marsman, Hendrik, additional, van Ruler, Oddeke, additional, Tanis, Pieter, additional, Westerduin, Emma, additional, Wicherts, Dennis, additional, Das, Parthasarathi, additional, Essapen, Sharadah, additional, Frost, Victoria, additional, Glennon, Ana, additional, Gray, Catherine, additional, Hussain, Anwar, additional, McNichol, Lisa, additional, Nisar, Pasha, additional, Scott, Humphrey, additional, Trickett, Jonathan, additional, Trivedi, Prateesh, additional, White, Daniel, additional, Amarnath, Talakalukoppa, additional, Ardley, Rohan, additional, Gupta, Robin, additional, Hall, Emily, additional, Hodgkins, Kathryn, additional, Narula, Harjeet, additional, Sewell, Terri-Ann, additional, Simms, John M, additional, Toms, Julie, additional, White, Tim, additional, Atkinson, Angela, additional, Beral, Dan, additional, Lancaster, Nicola, additional, Mackenzie, Felicity, additional, Wilson, Tim, additional, Cruttenden-Wood, David, additional, Gibbins, Jackie, additional, Halls, Mark, additional, Hill, Dennise, additional, Hogben, Karen, additional, Jones, Stephanie, additional, Lamparelli, Michael J, additional, Lewis, Mark, additional, Moreton, Sarah, additional, Ng, Paul, additional, Oglesby, Arabis, additional, Orbell, James, additional, Stubbs, Benjamin, additional, Subramanian, Krishnan, additional, Talwar, Anjay, additional, Wilsher, Simon, additional, Al-Rashedy, Mohammed, additional, Fensom, Catherine, additional, Gok, Muhammed, additional, Hardstaff, Lisa, additional, Malik, Kamran, additional, Sadat, Mohammed, additional, Townley, Barbara, additional, Wilkinson, Lesley, additional, Cosier, Tracey, additional, Mangam, Sudhakar, additional, Rabie, Mohamed, additional, Broadley, Graham, additional, Canny, John, additional, Fallis, Simon, additional, Green, Nikki, additional, Hawash, Ahmed, additional, Karandikar, Sharad, additional, Mirza, Mehboob, additional, Rawstorne, Edward, additional, Reddan, Julie, additional, Richardson, Jonathan, additional, Thompson, Chris, additional, Waite, Kathryn, additional, Youssef, Haney, additional, De Nes, Lindsey, additional, Rosenstock, Steffen, additional, Strandfelt, Pernille, additional, Westen, Mikkel, additional, Aryal, Kamal, additional, Kshatriya, Kirosh Shankar, additional, Lal, Roshan, additional, Velchuru, Vamsi, additional, Wilhelmsen, Elva, additional, Akbar, Ayesha, additional, Antoniou, Anthony, additional, Clark, Sue, additional, Datt, Pooja, additional, Goh, Jason, additional, Jenkins, Ian, additional, Kennedy, Robin, additional, Maeda, Yasuko, additional, Nastro, Piero, additional, Owen, Harriet, additional, Phillips, Robin KS, additional, Warusavitarne, Janindra, additional, Bradley-Potts, Joanne, additional, Charleston, Peter, additional, Clouston, Hamish, additional, Duff, Sarah, additional, Fatayer, Taher, additional, Gipson, Anna, additional, Heywood, Nick, additional, Junejo, Muneer, additional, Kennedy, James, additional, Lalor, Helen, additional, Manning, Chris, additional, McCormick, Richard, additional, Parmar, Kathryn, additional, Preston, Stephen, additional, Ramesh, Aswatha, additional, Sharma, Abhiram, additional, Telford, Karen, additional, Adeosun, Abidemi, additional, Hammond, Toby, additional, Smolen, Susan, additional, Topliffe, Joanne, additional, Docherty, James G, additional, Lim, Michael, additional, Macleod, Kathleen, additional, Monaghan, Eimar, additional, Patience, Lesley, additional, Thomas, Ian, additional, Walker, Kenneth G, additional, Walker, Michael, additional, Watson, Angus JM, additional, Burgess, Amanda, additional, Ghanem, Yasser, additional, Glister, Georgina, additional, Kapur, Sandeep, additional, Paily, Abhilash, additional, Pal, Atanu, additional, Ravikumar, Rathinam, additional, Rosbergen, Melissa, additional, Sargen, Kevin, additional, Speakman, Christopher, additional, Agarwal, Anil K, additional, Banerjee, Amlan, additional, Borowski, David, additional, Garg, Dharmendra, additional, Gill, Talvinder, additional, Johnston, Tracey, additional, Kelsey, Susan, additional, Munipalle, Phanibhushana Chakravarthy, additional, Tabaqchali, Mohamed, additional, Wilson, Deborah, additional, Acheson, Austin, additional, Cripps, Heather, additional, El-Sharkawy, Ahmed, additional, Ng, Oliver, additional, Sharma, Parveen, additional, Ward, Kym, additional, Chandler, Dawne, additional, Courtney, Edward, additional, Bunni, John, additional, Butcher, Katrina, additional, Dalton, Stephen, additional, Flindall, Ian, additional, Katebe, Joyce, additional, Roy, Pratik, additional, Tate, Jeremy, additional, Vincent, Tracy, additional, Williamson, Michael ER, additional, Wood, James, additional, Bignell, Mark, additional, Branagan, Graham, additional, Broardhurst, Jack, additional, Chave, Helen, additional, Dean, Hilary, additional, D'Souza, Nigel, additional, Foster, Gemma, additional, Sleight, Simon, additional, Sutaria, Rupesh, additional, Ahmed, Ishmail, additional, Budhoo, Misra Rai, additional, Colley, Julie, additional, Cruickshank, Neil, additional, Gill, Kathryn, additional, Hayes, Anne, additional, Joy, Howard, additional, Kamabjha, Carrington, additional, Plowright, James, additional, Radley, Simon, additional, Rea, Mr, additional, Thumbe, Vijay, additional, Varghese, Philip, additional, Wilkin, Richard, additional, Zulueta, Elzbieta, additional, Allsop, Lynne, additional, Atkari, Bence, additional, Badrinath, Krishnamurthy, additional, Daliya, Prita, additional, Dube, Mukul, additional, Heeley, Cheryl, additional, Hind, Richard, additional, Nash, Dominic, additional, Palfreman, Andrea, additional, Peacock, Oliver, additional, Watson, Nicholas, additional, Blodwell, Michelle, additional, Javaid, Ali, additional, Mohamad, Ashiq, additional, Muhammad, Karim, additional, Qureshi, Nafees, additional, Ridgway, Stephanie, additional, Siddiqui, Kamran, additional, Solkar, Mamoon, additional, Vere, Joanne, additional, Wordie, Alexander, additional, Chang, Jessica, additional, Elgaddal, Sanaa, additional, Green, Marie, additional, Hollyman, Marianne, additional, Mirza, Nazzia, additional, Rankin, Jayne, additional, Williams, Graham, additional, Ali, Wadah, additional, Hardwick, Anne, additional, Mohamed, Zakir, additional, Navid, Ahmad, additional, Netherton, Kimberley, additional, Obreja, Mugurel, additional, Rao, Milind, additional, Stringer, Joanna, additional, Tennakoon, Athula, additional, Bullen, Timothy, additional, Butt, Mansoor, additional, Dawson, Robin, additional, Dawson, Sarah, additional, Farmer, Martin, additional, Garimella, Veerabhadram, additional, Gates, Zoe, additional, Wilkings, Lisa, additional, Yeomans, Neil, additional, Adedeji, Olufunso, additional, Alalawi, Rashid, additional, Al Araimi, Aamed, additional, Ashraf, Shazad, additional, Bach, Simon, additional, Beggs, Andrew, additional, Cagigas, Carmen, additional, Dattani, Mit, additional, Dimitriou, Nikolletta, additional, Ghods-Ghorbani, Manijeh, additional, Gourevitch, David, additional, Haydon, Geoffrey, additional, Ismail, Tariq, additional, Keh, Christopher, additional, Morton, Dion G, additional, Narewal, Mandip, additional, Papettas, Trifonas, additional, Pinkney, Tom, additional, Poh, Aaron, additional, Ranstorne, Edward, additional, Royle, Timothy J, additional, Shah, Tahir, additional, Singh, Jagdeep, additional, Smart, Chris, additional, Suggett, Nigel, additional, Tayyab, Muhammad, additional, Vijayan, Deepak, additional, Vohra, Ravinder, additional, Wairaich, Naseem, additional, Yeung, Denise, additional, Bamford, Richard, additional, Chambers, Joanne, additional, Cotton, David, additional, Houlihan, Rebecca, additional, Kynaston, James, additional, Longman, Rob, additional, Lowe, Amelia, additional, Messenger, David, additional, Owais, Anwar, additional, Phillpott, Catherine, additional, Shabbir, Jamshed, additional, Baragwanath, Phil, additional, El-Sayed, Charlotte, additional, Gaunt, Anne, additional, Khatri, Chetan, additional, McCullough, Peter, additional, Ward, Stephen, additional, Obukofe, Ross, additional, Stroud, Robert, additional, Mason, David, additional, Williams, Nigel, additional, Wong, Ling S, additional, Chaudhri, Sanjay, additional, Cooke, Jill, additional, Cunha, Melissa, additional, Fairey, Howard, additional, Norwood, Michael, additional, Singh, Baljit, additional, Thomasset, Sarah, additional, Abbott, Sian, additional, Addison, Sarah, additional, Archer, James, additional, Church, Robert, additional, Holford, Erika, additional, Lenehan, Fionnaula, additional, Odogwu, Steve, additional, Richardson, Lisa, additional, Sidebotham, Jane, additional, Swan, Elaine, additional, Tilley, Alison, additional, Wagstaff, Lynda, additional, Amey, Isobel, additional, Baird, Yolanda, additional, Cripps, Neil, additional, Greenslade, Susanna, additional, Harris, Guy, additional, Levy, Bruce, additional, Mckenzie, Paul, additional, Misselbrook, Alison, additional, Moore, Sally, additional, Skull, Angela, additional, Nicol, Deborah, additional, Reddy, Bala, additional, Thrush, Jessica, additional, Iglesias Vecchio, Miriam, additional, Dunn, Yvonne, additional, Williams, Claire, additional, Furtado, Sanjay, additional, Gill, Michael, additional, Gilmore, Lydia, additional, Goldsmith, Paul, additional, Kocialkowski, Cezary, additional, Loganathan, Sadasivam, additional, Nath, Rabindra, additional, Paraoan, Marius, additional, Taylor, Tracey, additional, Allison, Andrew, additional, Allison, Joanna, additional, Curtis, Nathan, additional, Dalton, Richard, additional, D'Costa, Conrad, additional, Dennison, Godwin, additional, Foster, Jake, additional, Francis, Nader, additional, Gibbons, James, additional, Hamdan, Mohammed, additional, Lewis, Alison, additional, Ockrim, Jonathan, additional, Sharma, Rishabha, additional, Spurdle, Katie, additional, Varadharajan, Saseendran, additional, Aghahoseini, Assad, additional, Alexander, David J, additional, Bandyopadhyay, Dibyendu, additional, Bradford, Ian, additional, Chitsabesan, Praminthra, additional, Coleman, Zoe, additional, Gibson, Andrew, additional, Lasithiotakis, Kostas, additional, Panagiotou, Dimitrios, additional, Polyzois, Konstantinos, additional, Stojkovic, Stevan, additional, Woodcock, Nicholas, additional, Wright, Monica, additional, Hargest, Rachel, additional, Jackson, Richard, additional, Rajesh, Arumugam, additional, Ogunbiyi, Olagunju, additional, Slater, Andrew, additional, and Yu, Ly-Mee, additional

Published
2020
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25. Predictive Factors and Risk Model for Positive Circumferential Resection Margin Rate after Transanal Total Mesorectal Excision in 2653 Patients with Rectal Cancer

Author

S X, Roodbeen, F B, Lacy, S, Dieren, M, Penna, F, Ris, B, Moran, P, Tekkis, W A, Bemelman, R, Hompes, Adamina, Michel, Aigner, Felix, Al Furajii, Hazar, Albers, Benjamin, S Allison, Andrew, Arezzo, Alberto, J Arnold, Steven, Aryal, Kamal, Atallah, Sam, Austin, Ralph, Khurrum Baig, Mirza, Baloyiannis, Ioannis, Bandyopadhyay, Dibyendu, Banerjee, Saswata, Banky, Balazs, Baral, Joerg, Belgers, Eric, Bell, Stephen, Berti, Stefano, Biebl, Matthias, Bloemendaal, Bobby, Boni, Luigi, Bordeianou, Liliana, Borreca, Dario, I Bosker, Robbert J., Box, Benjamin, Boyce, Stephen, Bravo, Raquel, Den Broeck, Sylvie, Brown, Carl, Bruegger, Lukas, Brunner, Walter, Buchli, Christian, C Buchs, Nicolas, Buia, Alexander, Burt, Caroline, Cahill, Ronan, Pablo Campana, Juan, Campbell, Kenneth, Di Candido, Francesca, T Capolupo, Gabriella, Caricato, Marco, Caro-Tarrago, Aleidis, Cassinotti, Elisa, Caycedo, Antonio, Chandrasinghe, Pramodh, Chaudhri, Sanjay, Chernyshov, Stanislav, Chitsabesan, Praminthra, Christoforidis, Dimitri, A Clark, David, Coget, Julien, D Courtney, Edward, Cunningham, Chris, D’hooge, Pieter, D’hoore, Andre, Dagbert, Francois, J Dalton, Stephen, Dapri, Giovanni, Dawson, Robin, Dayal, Sanjeev, Delgado, Salvadora, Delrio, Paolo, Doerner, Johannes, Doornebosch, Pascal, Duff, Sarah, Erkinovich Dzhumabaev, Khasan, Edwards, Tom, Egenvall, Monika, Ravn Eriksen, Jens, Espin, Eloy, Estevez-Schwarz, Lope, Faes, Seraina, Fearden, Arne, Feleppa, Cosimo, Forgan, Tim, Forsmo, Havard, K Francis, Nader, Frontali, Alice, Fu, Cherylin, Gamage, Bawantha, Ignacio Rodriguez Garcia, Jose, Geissmann, Daniel, Geluwe, Bart, Gill, Kathryn, Glockler, Markus, Gloor, Severin, Javier Gomez, Carlos, Graaf, Eelco, Grolich, Tomas, Guido, Jutten, Hahnloser, Dieter, Hance, Julian, Harikrishnan, Athur, Haunold, Ingrid, Hayes, Julian, Hendrickx, Tom, Heriot, Alexander, Hoffmann, Theo-Julian, Hongwei, Yao, Huang, Joe, James, Horwood, Ial, Roshan, Ito, Masaaki, Janssens, Marc, Joy, Howard, Pagin Sao Juliao, Guilherme, Karimuddin, Ahmer, Katory, Mark, Killeen, Shane, Werner Kneist, Knol, Joep, Komen, Niels, Kukreja, Neil, Kusters, Miranda, Lacy, Antonio, Lakatos, Lorand, Lambrechts, Anton, Alvarez Laso, Carlos, Leao, Pedro, Lezoche, Emanuele, A Liberman, Sender, Lidder, Paul, Andrade Lima, Meylina, Lorenzon, Laura, Mackey, Paul, Maggiori, Leon, Zaur Mamedli, Zaman, Mansfield, Steve, Marcoen, Steven, Marcy, Tobias, Maroon, Tohmeh, Marta Pascual, Damieta, Marti, Lukas, Maslekar, Sushil, Mccallum, Iain, Mccarthy, Kathryn, Ramon Silveira Mendes, Carlos, Merrie, Arend, Michalopoulos, Antonios, Mikalauskas, Saulius, F Miles, Anthony W., C Mills, Sarah, Miroshnychenko, Yevgen, Mittermair, Christof, Molloy, Richard, Montroni, Isacco, Moore, Etienne, Moore, Tim, Mooslechner, Barbara, Morino, Mario, Moslein, Gabriela, Muratore, Andrea, Metodiev Mutafchiyski, Ventsislav, Myers, Alistair, Nicol, Deborah, Nieuwenhove, Yves, Nishizaki, Daisuke, John Nolan, Gregory, Ochsner, Alex, Hwan Oh, Jae, Collera Ormazabal, Pablo, Otero, Ana, Ouro, Susana, Panis, Yves, Papavramidis, Theodosios, Papen, Michael, Paraoan, Marius, Pastor, Carlos, Pastor, Enrique, Penchev, Dimitar, Pera, Miguel, Karim Perdawood, Sharaf, Oliva Perez, Rodrigo, Persiani, Roberto, Pfeffer, Frank, Terry Phang, P., Pichetto, Andrea, Pirenne, Yves, Pockney, Peter, Pooter, Karl, Poskus, Eligijus, Pros, Imma, Rajendran, Nirooshun, J Raval, Manoj, Rega, Daniela, Ricciardi, Rocco, Riel, Wouter, Ris, Frederic, Riss, Stefan, Alexander Rockall, Timothy, Romagnolo, Luis, Manuel Romero-Marcos, Juan, Roquete, Paulo, Rossi, Gustavo, Gomez Ruiz, Marcos, Rybakov, Evgeny, Sakai, Yoshiharu, Scala, Andrea, Millan Scheiding, Monica, Monica Millan, Gerald, Seva-Pereira, Gustavo, Sguinzi, Raffaella, A Shaikh, Irshad, Shalaby, Mostafa, Sharma, Abhiram, Sietses, Colin, Sileri, Pierpaolo, Simo, Vicente, Singh, Baljit, Slesser, Alistair, Kyung Sohn, Dae, Sosef, Meindert, Soravia, Claudio, Speakman, Christopher, Spinelli, Antonino, Sprundel, Frank, Steenkiste, Franky, L Stevenson, Andrew R., Stift, Anton, Storms, P., Studer, Peter, Konraad Talsma, Aaldert, J Tanis, Pieter, Tejedor, Patricia, La Terra, Antonio, Torkington, Jared, Jimenez Toscano, Marta, Tschann, Peter, Tuech, Jean-Jacques, Tuynman, Jurriaan, Tzovaras, George, Ugolini, Giampaolo, Vallribera, Francesc, Vanrykel, Filip, Vorburger, Stephan, Warner, Michael, J Warren, Oliver, Warrier, Satish, Warusavitarne, Janindra, Wegstapel, Henk, Weiss, Helmut, Witzig, Jacques-Alain, Wolff, Torsten, Wolthuis, Albert, Wu, Linus, Wynn, Greg, Zhongtao, Zhang, Zingg, Urs, Ziyaie, Dorin, Graduate School, AGEM - Digestive immunity, AGEM - Re-generation and cancer of the digestive system, CCA - Cancer Treatment and Quality of Life, Surgery, APH - Methodology, and International TaTME Registry Collaborative

Subjects
Male, Colorectal cancer, registry, circumferential resection margin, rectal cancer, risk factors, transanal total mesorectal excision, Adenocarcinoma, Aged, Cohort Studies, Disease-Free Survival, Endoscopic Mucosal Resection, Female, Follow-Up Studies, Humans, Length of Stay, Logistic Models, Middle Aged, Multivariate Analysis, Operative Time, Predictive Value of Tests, Proctectomy, Prognosis, Prospective Studies, Rectal Neoplasms, Registries, Risk Assessment, Survival Analysis, Transanal Endoscopic Surgery, Treatment Outcome, Margins of Excision, 0302 clinical medicine, Prospective cohort study, ddc:617, integumentary system, Incidence (epidemiology), food and beverages, Total mesorectal excision, 030220 oncology & carcinogenesis, Predictive value of tests, embryonic structures, 030211 gastroenterology & hepatology, Risk assessment, Cohort study, medicine.medical_specialty, animal structures, 03 medical and health sciences, medicine, Survival analysis, business.industry, fungi, medicine.disease, Surgery, Human medicine, business
Abstract

Objective: The aim of this study was to determine the incidence of, and preoperative risk factors for, positive circumferential resection margin (CRM) after transanal total mesorectal excision (TaTME). Background: TaTME has the potential to further reduce the rate of positive CRM for patients with low rectal cancer, thereby improving oncological outcome. Methods: A prospective registry-based study including all cases recorded on the international TaTME registry between July 2014 and January 2018 was performed. Endpoints were the incidence of, and predictive factors for, positive CRM. Univariate and multivariate logistic regressions were performed, and factors for positive CRM were then assessed by formulating a predictive model. Results: In total, 2653 patients undergoing TaTME for rectal cancer were included. The incidence of positive CRM was 107 (4.0%). In multivariate logistic regression analysis, a positive CRM after TaTME was significantly associated with tumors located up to 1 cm from the anorectal junction, anterior tumors, cT4 tumors, extra-mural venous invasion (EMVI), and threatened or involved CRM on baseline MRI (odds ratios 2.09, 1.66, 1.93, 1.94, and 1.72, respectively). The predictive model showed adequate discrimination (area under the receiver-operating characteristic curve >0.70), and predicted a 28% risk of positive CRM if all risk factors were present. Conclusion: Five preoperative tumor-related characteristics had an adverse effect on CRM involvement after TaTME. The predicted risk of positive CRM after TaTME for a specific patient can be calculated preoperatively with the proposed model and may help guide patient selection for optimal treatment and enhance a tailored treatment approach to further optimize oncological outcomes.

Published
2019

27. Students' participation in collaborative research should be recognised

Author

Borakati, Aditya, McLean, Kenneth, Drake, Thomas M., Harrison, Ewen M., Kamarajah, Sivesh K., Khatri, Chetan, Nepogodiev, Dmitri, Abbas, Minaam, Abdalkoddus, Muhammad, Abdel-Fattah, Areej, Abdelgalil, Reem, Abdikadir, Haweya, Adams, Ryan, Adams, Sarah, Adelaja, Inioluwa, Adeogun, Abiola, Adjei, Helena, Adlan, Amirul, Adwan, Hussamuddin, Aeyad, Sara, Aftab, Raiyyan, Afzul, Amir, Agarwal, Vani, Aglan, Hosam, Agrawal, Medha, Agrawal, Rishi, Ahmed, Fiza, Akhtar, Sobia, Akpenyi, Onyinye, Al-Attar, Maithem, Al-Ausi, Muhammed, Al-Khyatt, Waleed, Al-Mousawi, Alia, Al-Nasser, Zainab, Alagappan, Anand, Alberts, Justin, Alfa-Wali, Maryam, Ali, Abdulmajid, Ali, Adnan, Ali, Tamara, Alkhaffaf, Bilal, Allen, Rachael, Alubaidi, Kassem, Andah, Edemanwan, Anderson, Richard, Andrew, Kirstine, Ang, Andrew, Ang, Eshen, Anyomih, Theophilus, Archer, James, Archer, Matt, Arnell, Steven, Arnold, Matthew, Arora, Esha, Ashraf, Nadeem, Ashraf, Raees, Ashwood, Jordan, Asif, Usama, Atayi, Andrew, Auckburally, Sameera, Austin, Ralph, Azam, Sultana, Yahaya, Aishah Azri, Babatunde, Fiyin, Bach, Simon, Bachar, Roudi, Badran, Abdul, Baillie, Caroline, Balai, Edward, Baldwin, Alexander, Balian, Vartan, Banfield, Danielle, Bannard-Smith, Jonathan, Barker, Connor, Barmayehvar, Behrad, Barnfield, Jane, Bartlett, David, Bartlett, Richard, Baryeh, Kwaku, Basetti, Siddharth, Bateman, Kellie, Bath, Michael, Beamish, Andrew, Beasley, William, Beecroft, Simon, Begaj, Ardit, Beghal, Gurpreet, Belchos, Jessica, Bera, Katarzyna, Bergara, Tara, Betts, Anna, Bhangu, Aneel, Bhaskaran, Gayathri, Bhatti, Amina, Bica, Mihai, Billyard, Caitlin, Birkin, Emily, Blazeby, Jane, Blege, Harry, Blencowe, Natalie, Blore, Christopher, Boddy, Alex, Boissaud-Cooke, Matthew, Bolina, Anita, Bolton, William, Bosanquet, David, Bowley, Doug, Boyce, Kathryn, Branagan, Graham, Brayley, Jessica, Brecher, Joanna, Bresges, Kristina, Briggs, Emily, Broll, Ryan, Brown, Damien, Brown, Elliot, Brown, Leo, Brown, Robin, Brown, Rory, Bruce, Connor, Bruce, Pepa, Buckle, Rory, Budd, Emily, Buka, Richard, Burke, Dermot, Burke, Joshua, Burman, Alisha, Burney, Laura, Burrows, Amy, Bux, Mohammed, Cahill, Ronan, Calabria, Clementina, Camilleri-Brennan, Julian, Campbell, Amy, Campbell, Bill, Cant, Matthew, Cao, Yun, Carlson, Sophie, Carr, Grace, Carr, Luke, Carr, Rebecca, Carr, Richard, Cartwright, Eleanor, Castle, Alice, Cattle, Kirsty, Cave, Daniel, Chapman, Stephen, Charalabopoulos, Alexandros, Chaudhri, Sanjay, Chaudhry, Ahmad, Chauhan, Paresh, Chauhan, Priyesh, Chebbout, Ryad, Chen, Yunzi, Chenciner, Louisa, Cheng, Jingjie, Cheng, Natalie, Chew, Lin, China, Zenab, Chitnis, Abhishek, Chitsabesan, Praminthra, Choi, Paul, Choi, Sarah, Choudhry, Mariam, Choy, Chern, Ciurleo, Claudia, Claireaux, Henry, Coe, Peter, Cole, Simon, Concannon, Katy, Cope, Edward, Corbridge, Olivia, Court, Jessica, Cox, Louise, Craig-Mcquaide, Anna, Cresswell, Ben, Crozier, Lauren, Cruickshank, Neil, Cuckow, Lucy, Cui, Helen, Cumber, Elspeth, Cumming, Sarah, Cundy, Olivia, Cunha, Melissa, Cunha, Pedro, Cunliffe, Laura, Dada, Jazleen, Daliya, Prita, Dalli, Jeffrey, Daniels, Ian, Daniels, James, Daoub, Ahmed, Dar, Sabeera, Das, Emma, Das, Kaustuv, Davies, Emily, Davies, Gareth, Davies, Kirsty, Davies, Kristen, Davies, Rachel, Dawe, Victoria, Lucas de Carvalho, Joshua, De Jong, Katie, Deasy, Katherine, Deekonda, Praveena, Deepak, Sahil, Desai, Henal, Desai, Karishma, Devlin, Ryan, Dewan, Nishat, Dhillon, Akashdeep, Dhillon, Priya, Dhir, Tanya, Di Saverio, Salomone, Diamond, Julia, Dib, Peter, Dimitriadis, Panagiotis A., Dindyal, Shiva, Doe, Matthew, Doehrty, Ciaran, Dogra, Tara, Doshi, Arpan, Downey, Alison, Doyle, Joseph, Draper, Ashleigh, Duff, Sarah, Duncumb, Joseph, Dupre, Sophie, Durno, Justine, Dzieweczynski, Michal, Eardley, Nicola, Easby, Sarah, Easdon, Sam, Ebdewi, Hamdi, Eccles, Lydon, Edwards, Jacob, Eedarapalli, Padma, Elbuzidi, Mohamed, Elder, Patrick, Elliott, Lucy, Elsaddig, Malaz, Embury-Young, Ysabelle, Emesih, Sophie, Engledow, Alec, English, William, Episkopos, Christos, Epstein, Jonathan, Esmail, Rahim, Fatayer, Taher, Favero, Nicolò, Fearnhead, Nicola, Feldman, Maxine, Fennelly, Evelyn, Fenwick, Stephen, Ferguson, Lucie, Fergusson, Stuart, Fessas, Petros, FitzGerald, Isabel, Fitzgerald, J. Edward, Fitzpatrick, Harry, Fletcher, Daniel, Forjoe, Tonia, Forte, Beniamino, Fowler, Alex, France, Benjamin, Francis, Abraham, Francis, Niroshan, Francis, Sunil, Freeman, Sam, Fretwell, Vicky, Fung, Teresa, Furness, Hugh, Gallagher, Michael, Gallagher, Stuart, Gao, Chuanyu, Garard, Lothaire, Gardner, Shona, Gaukroger, Andrew, George, Daniel, George, Simi, Ghaddar, Jamal, Ghaffar, Ali, Ghouse, Shamira, Gilbert, Amanda, Gill, Ashveen, Giovinazzo, Francesco, Girling, Carey, Giwa, Lolade, Glasbey, James, Glen, Paul, Goble, Mary, Godfrey, Jenna, Goel, Shreya, Goh, Wenn, Gohil, Kajal, Gokani, Shyam, Gold, David, Golding, David, Gonzalez-Ciscar, Andrea, Goodson, Ross, Gough, Melissa, Govil, Shubhangi, Gower, Thomas, Graham, Christopher, Gray, Sam, Green, Patrick, Greenhalgh, Samuel, Gregoriou, Kyriacos, Gribbell, Rhiannon, Gribbon, Mary Catherine, Grieco, Charlotte, Griffiths, Emma, Griffiths, Ewen, Griffiths, Nathan, Griffiths, Sara, Grossart, Cathleen, Guerero, Daniel, Guillotte, Christianne, Gupta, Rishi, Guy, Claire, Gwozdz, Adam, Haddow, James, Hafiz, Shazia, Halkias, Constantine, Hall, Elisabeth, Hamid, Hasseb, Hamilton, Emma, Harbhajan Singh, Gurvinder Singh, Hardman, John, Harries, Rhiannon, Harris, Rhydian, Harrogate, Suzanne, Harty, Megan, Harvey, Jessica, Hashemi, Rahima, Hassane, Ahmed, Hawkins, Helen, Hawthorne, Thomas, Hayes, John, Hazenberg, Phoebe, Heath, Harry, Hebbar, Madhusoodhana, Heer, R., Hegarty O'Dowd, Roisin, Henshall, David, Herrod, Philip, Hester, Elizabeth, Heywood, Emily, Heywood, Nick, Hill, Frances, Hill, James, Hill, Kirsty, Ho, May, Hollyman, Marianne, Holroyd, David, Home, Joseph, Hornby, Steve, Horne, Laura, Horseman, Charlotte, Hosamuddin, Huma, Hough, Amy, Hourston, George, Hudson-Peacock, Nathan, Hughes, Belinda, Hughes, Katie, Huppatz, Isabel, Hurst, Penelope, Hussain, Mahrukh, Hussain, Shoaib Fahad, Hussain, Syeda, Hutchings, Imogen, Ibrahim, Bilal, Imam, Lema, Ingham, Rory, Ingleton, Rose, Iqbal, Rizwan, Isherwood, Jenny, Islim, Abdurrahman, Ismail, Omar, Iyer, Shashank, Jackman, Toby, Jain, Prashant, Jamal, Nadeem, Jamal, Sabine, James, Ellen, Jayaratne, Nirmitha, Jeffreys, Nathan, Jhala, Hiral, Johnson, Courtney, Johnston, Zoe, Jones, Conor, Jones, Emma-Jane, Jones, Keaton, Jones, Victor, Joseph, Roshan, Joshi, Dilan, Joyce, Holly, Joyner, Claire, Kale, Aditya, Kanabar, Sagar, Kanapeckaite, Lina, Kankam, Hadyn, Kaptanis, Sarantos, Karam, Edward, Karponis, Dimitrios, Karunatilleke, Anne, Kasivisvanathan, Veeru, Kaur, Geeta, Kauser, Samina, Keelty, Nigel, Kelly, Denise, Kennett, Jessica, Kerr, Molly, Kerwan, Ahmed, Khajuria, Apoorva, Khalil, Mostafa, Khaliq, Mehnoor, Khan, Ayushah, Khan, Hamzah, Khan, Haroon, Khan, Maaz, Khan, Maria, Khan, Shahab, Khan, Kaywaan, Khaw, Rachel, Kheterpal, Ashni, Khonsari, Parisa, Kiandee, Miraen, Kim, Samuel, Kim, Suji, Kim, Sung-Hee, King, Harry, Kinsella, Anna, Kishore, Ajit, Klimach, Stefan, Kolias, Angelos G., Kolodziejczyk, Anna, Kong, Chia Yew, Kong, Tseun Han James, Kouli, Omar, Kukran, Sebi, Kukran, Sevi, Kumaran, Geev, Kutuzov, Vladislav, Laing, Chris, Laing, Georgina, Lal, Kulvinder, Lalor, Peter, Lambert, Joel, Lambotharan, Sai Geethan, Lancaster, Eve, Latter, Jasmine, Latter, Michelle, Lau, Kenny, Lazarou, Alexa, Leadon, Madeline, Lee, Gabriel, Lee, Jeyoung, Lee, Kathryn, Lee, Matthew, Lee, Samuel, Lee, Zong, Leung, Edward, Lewis, Thomas, Li, Hansen, Li, Mimi, Liew, Wan Jane, Liew, Yao Ren, Light, Alexander, Lilis, Lydia, Lim, Diana, Lim, Hui, Lim, Joseph, Lim, Zhi, Liu, Siyin, Lloyd, James, Logan, Andrew, Loganathan, Priya, Long, M., Longstaff, Lydia, Rojas, Luisa Lopez, Lovegrove, Richard, Lowe-Zinola, Jack, Morrell, Byron Lu, Luck, Joshua, Luhmann, Andreas, Lunawat, Surabhika, Lund, Jon, Luo, Cong, Luo, Lorna, Lyell, Iona, Lykoudis, Panagis, Macdonald, Jonathan, Mackenzie, Aliya, Magee, Conor, Mahankali-Rao, Pooja, Mahawar, Kamal, Mahfooz, Mehreen, Mahmood, Faisal, Makwana, Samir, Malik, Tom, Mallick, Sohaib, Manalayil, Jyothis, Mandishona, Tinaye, Mangam, Sudhakar, Manimaran, Maniragav, Manimaran, Natarajan, Manson, Chris, Mansoor, Sufyan, Mansour, Fatima, Marcos Rodrigo, Alejandro, Markham, Nicholas, Marks, Maria, Marriott, Paul, Marsden, Hannah, Martin, Laura, Martins, Tiago, Mason, John, Mason, Luke, Masood, Mariam, Math, Nikhil, Mathew, Ginimol, Matthews, Jacob, Mayes, Jonathan, Mc Gee, Ursula, Mcallister, Ross, Mcallister, Sandra, Mccain, Scott, Mccann, Conor, Mccann, Emmet, McCarthy, Cathal, Mccoll, Gillian, Mcconaghie, Greg, Mcdermott, Ace, McDermott, Frank, Mcdougall, Rachel, McDowell, Mark, McFarlane, Gordon, McGregor, Richard, McKechnie, Doug, McKenna, Jillian, McKinstry, Scott, Mclachlan, Georgia, Mclean, E., McLennan, Elizabeth, McNair, Angus, Mealy, Kenneth, Mecia, Lauren, Mehta, Alexander, Mellan, Aidan, Menon, Arathi, Menzies, Donald, Mesbah, Zhubene, Messenger, David, Miller, George, Mishra, Aseem, Mistry, Sona, Mohamed, Tahira, Mushaini, Nisha Mohamed, Mohan, Midhun, Mohd Azmilssss, Ameerah, Mohite, Ajay, Moorthy, Krishna, Moradzadeh, Jalal, Morgan, Richard, Morley, Gabriella, Mortimer, Alice, Mownah, Hannah, Moxey, Paul, Mudalige, Gagira, Muhammad, Umarah, Munday, Samuel, Murphy, Ben, Murphy, Ciaran, Murray, Caoimhe, Murray, Hannah, Murray, Michael, Murtaza, Mohammed Ibrar, Mushtaq, Jameel, Mustafa, Ameer, Mustafa, Shams, Myers, Laura, Myers, Sam, Naasan, Adeeb, Nadeem, Kiran, Naeem, Hanzla, Naik, Prashant, Nair, Arun, Nambiar, Keshav K., Naqi, Muhammad, Naqvi, Zehra, Neo, Yan Ning, Neophytou, Georgia Irene, Neville, Jonathan, Newman, Tom, Ng, Benjamin, Ng, Guat, Ng, Jing Qi, Ng, Vincent, Ng, Zhan Herr, Ni Bhoirne, Maire, Nicholas, James, Nicholson, Gary, Ninkovic-Hall, George, Nixon, Gemma, Norwood, Mike, Noton, Toby, Nourzaie, Romman, Novell, Richard, Nyanhongo, Donald, O'Brien, James, O'Kane, Rory, O'Neill, Stephen, O'Sullivan, Hugh, Oakley, Thomas, Ogbuokiri, Chinomso, Ogunleye, Oluwafunto, Oh, Su, Okorocha, Emezie, Olivier, James, Ologunde, Rele, Omara, Sharif, Ormrod, Alice, Osborne, Caroline, Osmanska, Joanna, Owasil, Raisah, Owczarek, Sebastian, Ozcan, Ezgi, Palaniappan, Sri, Palazzo, Francesco, Palkhi, Abbas, Pandey, Gargi, Park, James, Parker, Jennifer, Parry, Anna, Parsonage, James, Passby, Lauren, Patel, Bhavi, Patel, Bhavik, Patel, Chantal, Patel, Dinisha, Patel, Kirtan, Patel, Panna, Patel, Pratiksha, Patel, Trupesh, Pathmarajah, Mariasoosai, Patil, Amogh, Patil, Pradeep, Patrick, Yusuf, Pearce, Jessica, Pearce, Lyndsay, Peirce, Colin, Peiris, Bryony, Pendrill, Amy, Periketi, Sreelata, Perry, Michael, Petrov, George, Phillips, Charlotte, Pike, Grace, Pinho-Gomes, Ana Catarina, Polly, Parhana, Ponweera, Arachchige, Poolovadoo, Yanish, Poonawala, Raunak, Popova, Petya, Pournaras, Dimitri, Powell, Brooke, Prabakaran, Praveena, Prakash, Esha, Pratumsuwan, Tapani, Prem Kumar, Anusha, Puddy, Helen, Pullinger, Michael, Punjabi, Nikita, Putt, Oliver Charles, Qadir, Omar, Qamar, Mubasher, Quinn, Patrick, Qureshi, Arham, Rabie, Mohamed, Radford, Angus, Radhakrishnan, Anand, Radotra, Ansh, Rafiq, Nasir, Rahem, Aria, Rahman, Nahim, Rahman, Syed, Rajagopal, Ramesh, Rajan, Nick, Rajaraman, Nikitha, Rajendran, Sumetha, Ramachenderam, Liandra, Ramakrishnan, Divya, Ramjas, Denisha, Rammell, James, Rampal, Ritika, Ramsay, George, Randhawa, Ratan, Rea, Ellis, Rees, Stephanie, Rehman, Saad, Rehman, Salwah, Rehnnuma, Nabila, Rejayee, Melina, Rob, Zakaria, Roberts, Charlotte, Roberts, Grace, Roberts, Ben, Robinson, Harry, Robinson, Stephen, Rogers, Ailin, Rogers, Alex, Rook, William, Ross, Talisa, Roy, Chloe, Rushd, Azelea, Rutherford, Duncan, Saat, Michael, Sadanand, Kaushik, Sagar, Rebecca, Sagoo, Harkiran, Saha, Arin, Sahnan, Kapil, Sait, Mohammed Salik, Sait, Saif, Salekin, Damien, Salem, Mostafa, Salloum, Nadia, Sanders, Emma, Sandhu, Jasmesh, Sandhu, N., Sandison, Lorna, Sandland-Taylor, Laura, Sangal, Ron, Sanghera, Chandan, Saramunda, Josephine, Satterthwaite, Lauren, Schramm, Moritz, Scott, Rupert, Searle, Chloe, Seehra, Harkiran, Segura-Sampedro, Juan Jose, Sekhon Inderjit Singh, Harpreet Kaur, Seraj, Shaikh Sanjid, Seth, Ishani, Sethi, Rajiv, Shah, Apar, Shaid, Mario, Shaikh, Shafaque, Shamali, Awad, Sharkey, Elizabeth, Sharma, Abhi, Sharma, Neil, Sharma, Sachin, Shenoy, Aniruddh, Shergill, Maleasha, Shirazi, Shahram, Siddiqui, Imran, Sim, Raykal, Simmonds, Lucy, Simon, Andrew, Simpson, William, Singh, Bharpoor, Singh, J., Singh, Prashant, Sinha, Anant, Sinha, Sidhartha, Sinnerton, Robert, Sivakumar, Chaamanti, Skelly, Brendan, Slater, Richard, Small, Samuel, Smart, Neil, Smart, Yat Wing, Smith, Alexander, Smith, Charlotte, Smith, Jason, Smith, Rebecca, Smith, Scott, Sodde, Peter, Soh, Zhi Min, Sonsale, Aniket, Soualhi, Ahmed, Spearman, John, Spencer, Robert, Spiers, Harry, Stather, Philip, Stoddart, Michael, Storey, Bradley, Stringer, Howard, Stringfellow, Thomas, Stubbs, Ben, Sukir, Niv, Sukirthan, Nivian, Suleman, Yasir, Sureshkumar, Aparnah, Suri, Ashwin, Swartbol, Timen, Tahir, Hyder, Tan, E. Tian, Tan, Huai Ling, Tan, Laura, Tang, Alethea, Taribagil, Priyal, Tay, Yao Zong, Taylor, Beth, Taylor, Zara, Thatcher, Alexandra, Thavayogan, Rachel, Thomaa, Michael, Thomas, Daniah, Thomas, Jenny, Thomas, Paul, Pinkney, Thomas, Thompson, Chris, Ting, Mag, Toner, Ethan, Tong, Godwin, Torkington, Jared, Traish, Molly, Triniman, Miles, Trotter, John, Tsang, Kwong, Turaga, Sanchit, Turley, Hannah, Turner, James, Urbonas, Tomas, Urquhart, Alexandra, Vadgama, Nimai, Vaidya, Aashay, van Boxel, Gijs, Vara, Swati, Varcada, Massimo, Varley, Rebecca, Varma, Dee, Vella-Baldacchino, Martinique, Venturini, Sara, Verma, Naina, Verma, Saurabh, Vernet, Gabrielle, Vipond, Mark, von Roon, Alex, Wadood, Qasim, Waite, Kathryn, Walker, Lewis, Walker, Nathan, Wan, Jonathan C.M., Wang, Liyang, Wang, Xue, Ward, Alex, Ward, Thomas, Warnaar, Nienke, Warren, Lloyd, Warren, Oliver, Waters, Sam, Watson, Angus, Watson, Laura Jayne, Waugh, Dominic, Weinberg, Daniel, West, Malcolm, White, Carla, White, Tim, Whitehurst, Katharine, Whitham, Robert, Wijekoon, Tharindri, Wijeyaratne, Manuk, Wilkin, Richard, Wilkins, Alex, Williams, Adam, Williams, Gethin, Williams, Luke, Williams, Robert, Williamson, Andrew, Willson, Jacinthe, Wilson, Andrew, Wilson, Holly, Wilson, James, Wilson, Lizzie, Wilson, Megan, Wilson, Michael, Wilson, Rebekah, Wilson, Tim, Woin, Evelina, Wright, Esther, Wright, Jenny, Wroe, Nicholas, Wylie, Joanne, Xu, Yiwang, Yalamarthi, Satheesh, Yan, Angela, Yang, Narisu, Yardimci, Eda, Yasin, Ibrahim, Yasin, Ismael, Yasin, Noor, Yates, Joseph, Yau, Jih Dar, Yeoh, Tricia, Yip, Joshua, Yong, Cissy, Zaver, Vasudev, Zhelezniakova, Tatiana, and Zulkifli, Adreana

Published
2017
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31. Cross-linked thin poly(vinyl alcohol) membrane supported on polysulfone in tea polyphenol separation.

Author

Saxena, Mayank, Chaudhri, Sanjay G., Das, Arun K., Singh, Puyam S., and Bhattacharya, A.

Subjects
*TEA analysis, *POLYPHENOLS, *POLYVINYL alcohol, *CROSSLINKING (Polymerization), *MEMBRANE separation
Abstract

Cross-linked polymeric colloids are coated over porous polysulfone support by a simple method to prepare high-flux membrane for separation of tea polyphenols. The colloidal particles were prepared by electrostatic interaction and cross-linking between poly(vinyl alcohol) and maleic acid. The membrane exhibited >90% rejection of polyethylene glycol of 6000 Da molecular weight. The membranes exhibited flux of about 15-20 LMH with 70-90% polyphenol retention depending upon the coating and support types at 500 psi and had shown stability under continuous running of the separation experiments in water or methanol at pressurized condition. [ABSTRACT FROM AUTHOR]

Published
2019
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34. The colorectal surgeon's personality may influence the rectal anastomotic decision.

Author

Abbott, Sarah, Adedeji, Olufunso, Anderson, Robert, Armstrong, Aidan, Arnott, Bob, Arthur, Laura M., Bharathan, Bala, Campbell, Ken, Chapman, Mark, Chaudhri, Sanjay, Cook, Tim, Cope, Alexandra, Davies, Justin, Dworkin, Michael, Dawson, Peter, Durai, Rajaraman, El‐Masry, Sherif, Harikrishnan, Arthur, Hawkin, Paul, and Helley, Michael

Subjects
COLON diseases, RECTAL diseases, SURGEONS, PERSONALITY, SURGICAL anastomosis, DECISION making
Abstract

Aim: Colorectal surgeons regularly make the decision to anastomose, defunction or form an end colostomy when performing rectal surgery. This study aimed to define personality traits of colorectal surgeons and explore any influence of such traits on the decision to perform a rectal anastomosis. Method: Fifty attendees of The Association of Coloproctology of Great Britain and Ireland 2016 Conference participated. After written consent, all underwent personality testing: alexithymia (inability to understand emotions), type of thinking process (intuitive versus rational) and personality traits (extraversion, agreeableness, openness, emotional stability, conscientiousness). Questions were answered regarding anastomotic decisions in various clinical scenarios and results analysed to reveal any influence of the surgeon's personality on anastomotic decision. Results: Participants were: male (86%), consultants (84%) and based in England (68%). Alexithymia was low (4%) with 81% displaying intuitive thinking (reflex, fast). Participants scored higher in emotional stability (ability to remain calm) and conscientiousness (organized, methodical) compared with population norms. Personality traits influenced the next anastomotic decision if: surgeons had recently received criticism at a departmental audit meeting; were operating with an anaesthetist that was not their regular one; or there had been no anastomotic leaks in their patients for over 1 year. Conclusion: Colorectal surgeons have speciality relevant personalities that potentially influence the important decision to anastomose and could explain the variation in surgical practice across the UK. Future work should explore these findings in other countries and any link of personality traits to patient‐related outcomes. [ABSTRACT FROM AUTHOR]

Published
2018
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35. Prospective Audit of a Pathway for In-Patient Pain Management of Chronic Abdominal Pain: A Novel and Cost-Effective Strategy.

Author

Niraj, Gopinath and Chaudhri, Sanjay

Subjects
*THERAPEUTIC use of narcotics, *PAIN management, *ABDOMINAL pain, *AUDITING, *CHRONIC pain, *COST effectiveness, *LENGTH of stay in hospitals, *HOSPITAL wards, *INFLAMMATION, *MYOFASCIAL pain syndromes, *PHYSICIANS, *STEROIDS, *ULTRASONIC imaging, *DISCHARGE planning, *DISEASE exacerbation, *PATIENT readmissions, *TERTIARY care, *DISEASE complications, *ECONOMICS, *DIAGNOSIS
Abstract

Background. Unexplained abdominal pain is a common cause of hospital admission and utilizes significant resource. Current in-patient painmanagement of acute exacerbation of chronic abdominal pain is primarily directed at pharmacological and psychological management strategies in this group of complex patients. We adopted a novel approach that proved to be both clinically effective and cost-effective. Design. Adult patients admitted to a surgical ward with acute exacerbation of chronic abdominal pain referred to in-patient pain management were prospectively audited over a two-year period at a single tertiary centre. Methods. Management strategy focused on a somatic source as the predominant pain generator. Patients were offered ultrasound-guided trigger point injection with steroids within 48 hours of referral and were discharged when pain control was achieved. Subsequent care by the pain physician included targeted treatment of somatic component (repeated trigger point injection with steroids or pulsed radiofrequency treatment of trigger points). Results. We audited 43 patients referred to the inpatient pain management service over a two-year period. Four patients refused to undergo the diagnostic trigger point injection. Three patients with active visceral disease had a transient response to the injection. Thirty-six patients were diagnosed with abdominal myofascial pain syndrome and two-thirds of these patients were discharged home within 36 hours of the intervention. Conclusions. Abdominal myofascial pain syndrome is a poorly recognized cause of chronic abdominal pain, especially in patients with a past history of visceral inflammation. The novel strategy resulted in a significant reduction in opioid consumption, length of stay and readmission rate. [ABSTRACT FROM AUTHOR]

Published
2018
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36. Fabrication of efficient pervaporation desalination membrane by reinforcement of poly(vinyl alcohol)-silica film on porous polysulfone hollow fiber.

Author

Chaudhri, Sanjay G., Chaudhari, Jayesh C., and Singh, Puyam S.

Subjects
REVERSE osmosis, NANOFILTRATION, SALINE waters, PERMEABILITY, POROSITY
Abstract

ABSTRACT Pervaporation membrane technology is commercially successful in the dehydration of organic solvents, and the technology has potential for seawater desalination with high recovery because of its capability to treat highly saline water. But to make the technology advantageous over the other available membrane desalination technologies in terms of productivity flux without additional energy cost, the selective barrier layer is required to be extremely thin, defect-free, hydrophilic, and selective to water. In this work, we prepared an efficient membrane by reinforcing a highly water-permeable but continuous barrier layer of poly(vinyl alcohol)-silica (PVA-SiO2) hybrid material on porous polysulfone hollow fibers. The PVA-SiO2 in acidified and hydrated ethanol was aged at room temperature for a period to allow solvent evaporation to obtain the solution concentration desired for the reinforcement. The reinforced hollow fiber membrane with optimal PVA-SiO2 barrier layer thickness exhibited a performance with a flux of 20.6 L m−2 h−1 and 99.9% salt rejection from a saline feed of 2000 ppm NaCl at 333 K. The effects of PVA-SiO2, temperature, and feed salinity on the pervaporation performance of the membrane were also studied. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45718. [ABSTRACT FROM AUTHOR]

Published
2018
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43. Comparison of the initial reactant structure and crosslinked network of poly(dimethyl siloxane) membranes from different macromonomers.

Author

Singh, Puyam S., Jadav, Ghanshyam L., Aswal, Vinod K., Das, Arun K., Kumar, Sugam, Kansara, Ankit M., Chaudhri, Sanjay G., and Brahmbhatt, Harshad

Subjects
CROSSLINKING (Polymerization), NANOSTRUCTURED materials, VOLATILE organic compounds, POLYDIMETHYLSILOXANE, CHEMICAL precursors
Abstract

ABSTRACT Some of the best entities for the removal of volatile organic pollutants from water, poly(dimethyl siloxane) (PDMS) membranes from two types of initial PDMS precursors, were thoroughly investigated. In both the cases, the sizes of the initial macromonomers increased because of the crosslinking in the liquid state, and they exhibited Gaussian chain statistics, which were condensed by further crosslinking to the formation of the membranes. The structures of both the membrane types exhibited large interchain spacing on swelling; this implied a high degree of chain mobility. Their structural properties were corroborated by their separation performances. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 41461. [ABSTRACT FROM AUTHOR]

Published
2015
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44. Simultaneous stoma reinforcement and perineal reconstruction with biological mesh - A multicentre prospective observational study.

Author

Aslam MI, Baloch N, Mann C, Nilsson PJ, Maina P, Chaudhri S, and Singh B

Abstract

Introduction: The optimal method for perineal reconstruction after extralevator abdominoperineal excision (elAPE) for low rectal cancer remains controversial. This study aimed to assess whether simultaneous perineal reconstruction and parastomal reinforcement with Strattice™ Reconstructive Tissue Matrix after elAPE could prevent hernia formation., Methods: In this prospective, multicentre, observational, non-comparative study of consecutive patients undergoing elAPE for low rectal cancer underwent simultaneous perineal reconstruction and colostomy site reinforcement with Strattice™ mesh. All patients underwent long course chemoradiotherapy prior to surgery and had excision of the coccyx. Patients were assessed for perineal wound healing at 7 day, 1, 3, 6 and 12 months, perineal and parastomal hernia defects on clinical and radiological assessment at 1 year following surgery., Results: 19 patients (median age = 67 years, median BMI = 26, M:F = 11:8) were entered the study. 10 (52.6%) patients underwent laparoscopic elAPE. The median length of post-operative stay was 9 days. Complete wound healing was observed for 8(42%) patients at 1 month, 12(63%) at 3 months, and 19(100%) patients at 12 months. Median time for radiological and clinical assessment for hernias was 12 months. No perineal hernia was detected in 17 patients following CT assessment. Dynamic MRI was undertaken in 11 patients at 12 months and all showed no evidence of perineal hernia. 3 (16%) patients had a parastomal hernia detected radiologically. No mesh was removed during the 12 months follow up period., Conclusion: Perineal and parastomal reconstruction with biological mesh is a feasible approach for parastomal and perineal hernia prevention after laparoscopic and open elAPE.

Published
2018
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