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221 results on '"Chatzidimitriou, Dimitrios"'

1. Breaking Reciprocity in a non-Hermitian Photonic Coupler with Saturable Absorption

Author

Chatzidimitriou, Dimitrios, Pitilakis, Alexandros, Yioultsis, Traianos, and Kriezis, Emmanouil E.

Subjects
Physics - Optics
Abstract

We study the breaking of reciprocity in non-Hermitian coupled photonic waveguides by the simultaneous action of the nonlinear effect of saturable absorption, and the presence of exceptional points. The nonlinear response of such a system is studied in depth, giving physical insight into the operational principles and fundamental limitations, while producing analytical and semi-analytical results for the transmission and nonreciprocal intensity range. We numerically validate the theoretical results and assess important performance metrics for the nonreciprocal operation of such a device. This novel class of passive non-resonant devices can offer on-chip broadband nonreciprocal operation, making them potentially very important for high-speed applications., Comment: 10 pages, 6 figures, submitted to Physical Review A on 15-Feb-2021

Published
2021
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2. Asymmetric Si-slot Coupler with Nonreciprocal Response Based on Graphene Saturable Absorption

Author

Pitilakis, Alexandros, Chatzidimitriou, Dimitrios, Yioultsis, Traianos V., and Kriezis, Emmanouil E.

Subjects
Physics - Optics, Physics - Applied Physics
Abstract

We present the study of a proof-of-concept integrated device that can be used as a nonlinear broadband isolator. The device is based on the asymmetric loading of a highly-confining silicon-slot photonic coupler with graphene layers, whose ultrafast and low-threshold saturable absorption can be exploited for nonreciprocal transmission between the cross-ports of the coupler. The structure is essentially a non-Hermitian system, whose exceptional points are briefly discussed. The nonlinear device is modeled with a coupled Schrodinger equation system whose validity is checked by full-vector finite element-based beam-propagation method simulations in CW. The numerically computed performance reveals a nonreciprocal intensity range (NRIR) in the vicinity of 100 mW peak power with a bandwidth spanning tens of nanometers, from CW down to ps-long pulses. Finally, the combination of saturable absorption and self-phase modulation (Kerr effect) in graphene is studied, indicating the existence of two NRIR with opposite directionality., Comment: 10 pages, 10 figures. Published online at 5 April 2021 in the IEEE Journal of Quantum Electronics

Published
2021
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3. Molecular Epidemiology of SARS-CoV-2 in Greece Reveals Low Rates of Onward Virus Transmission after Lifting of Travel Restrictions Based on Risk Assessment during Summer 2020.

Author

Kostaki, Evangelia, Pavlopoulos, Georgios, Verrou, Kleio-Maria, Ampatziadis-Michailidis, Giannis, Harokopos, Vaggelis, Hatzis, Pantelis, Moulos, Panagiotis, Siafakas, Nikolaos, Pournaras, Spyridon, Hadjichristodoulou, Christos, Chatzopoulou, Fani, Chatzidimitriou, Dimitrios, Panagopoulos, Periklis, Lourida, Panagiota, Argyraki, Aikaterini, Lytras, Theodoros, Sapounas, Spyros, Gerolymatos, Gerasimos, Panagiotakopoulos, Georgios, Prezerakos, Panagiotis, Tsiodras, Sotirios, Sypsa, Vana, Hatzakis, Angelos, Anastassopoulou, Cleo, Spanakis, Nikolaos, Tsakris, Athanasios, Dimopoulos, Meletios, Kotanidou, Anastasia, Sfikakis, Petros, Kollias, Georgios, Magiorkinis, Gkikas, and Paraskevis, Dimitrios

Subjects
SARS-CoV-2, molecular epidemiology, phylogeography, public health, travel restrictions
Abstract

The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread rapidly during the first months of 2020 and continues to expand in multiple areas across the globe. Molecular epidemiology has provided an added value to traditional public health tools by identifying SARS-CoV-2 clusters or providing evidence that clusters based on virus sequences and contact tracing are highly concordant. Our aim was to infer the levels of virus importation and to estimate the impact of public health measures related to travel restrictions to local transmission in Greece. Our phylogenetic and phylogeographic analyses included 389 full-genome SARS-CoV-2 sequences collected during the first 7 months of the pandemic in Greece and a random collection in five replicates of 3,000 sequences sampled globally, as well as the best hits to our data set identified by BLAST. Phylogenetic trees were reconstructed by the maximum likelihood method, and the putative source of SARS-CoV-2 infections was inferred by phylogeographic analysis. Phylogenetic analyses revealed the presence of 89 genetically distinct viruses identified as independent introductions into Greece. The proportion of imported strains was 41%, 11.5%, and 8.8% during the three periods of sampling, namely, March (no travel restrictions), April to June (strict travel restrictions), and July to September (lifting of travel restrictions based on thorough risk assessment), respectively. The results of phylogeographic analysis were confirmed by a Bayesian approach. Our findings reveal low levels of onward transmission from imported cases during summer and underscore the importance of targeted public health measures that can increase the safety of international travel during a pandemic. IMPORTANCE Our study based on current state-of-the-art molecular epidemiology methods suggests that virus screening and public health measures after the lifting of travel restrictions prevented SARS-CoV-2 onward transmission from imported cases during summer 2020 in Greece. These findings provide important data on the efficacy of targeted public health measures and have important implications regarding the safety of international travel during a pandemic. Our results can provide a roadmap about prevention policy in the future regarding the reopening of borders in the presence of differences in vaccination coverage, the circulation of the virus, and the presence of newly emergent variants across the globe.

Published
2021

5. Targeted genotyping of COVID-19 patients reveals a signature of complement C3 and factor B coding SNPs associated with severe infection

Author

Tsiftsoglou, Stefanos A., Gavriilaki, Eleni, Touloumenidou, Tasoula, Koravou, Evaggelia-Evdoxia, Koutra, Maria, Papayanni, Penelope Georgia, Karali, Vassiliki, Papalexandri, Apostolia, Varelas, Christos, Chatzopoulou, Fani, Chatzidimitriou, Maria, Chatzidimitriou, Dimitrios, Veleni, Anastasia, Rapti, Evdoxia, Kioumis, Ioannis, Kaimakamis, Evaggelos, Bitzani, Milly, Boumpas, Dimitrios T., Tsantes, Argyris, Sotiropoulos, Damianos, Papadopoulou, Anastasia, Sakellari, Ioanna, Kokoris, Styliani, and Anagnostopoulos, Achilles

Published
2023
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6. Abstract 17570: Combining Genomic Profiling and Clinical Data Through Machine Learning Modeling for the Prediction of Coronary Artery Disease Severity: Insights From the Genetic SYNTAX Score (GESS) Trial

Author

Chatzopoulou, Fani, Mittas, Nikolaos, KARAGIANNIDIS, EFSTRATIOS, Papazoglou, Andreas S, STALIKAS, NIKOLAOS, Moysidis, Dimitrios V, Giannopoulos-Dimitriou, Alexandros, Saiti, Aikaterini, Ganopoulou, Maria, Papa, Anna, Chatzidimitriou, Dimitrios, Giannakoulas, George, Sianos, Georgios, Angelis, Lefteris, and Vizirianakis, Ioannis S

Published
2023
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7. Neutralizing antibody and T cell responses to SARS-CoV-2 vaccination in hematopoietic cell transplant recipients

Author

Gavriilaki, Eleni, Papadopoulou, Anastasia, Touloumenidou, Tasoula, Stavridou, Fani, Koravou, Evaggelia-Evdoxia, Giannaki, Maria, Papalexandri, Apostolia, Karavalakis, Georgios, Batsis, Ioannis, Kourelis, Andreas, Chatzopoulou, Fani, Chatzidimitriou, Dimitrios, Sotiropoulos, Damianos, Yannaki, Evangelia, Sakellari, Ioanna, and Anagnostopoulos, Achilles

Published
2022
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8. Hepatotoxicity assessment of innovative nutritional supplements based on olive-oil formulations enriched with natural antioxidants

Author

Prodromou, Sofia I., primary, Chatzopoulou, Fani, additional, Saiti, Aikaterini, additional, Giannopoulos-Dimitriou, Alexandros, additional, Koudoura, Loukia A., additional, Pantazaki, Anastasia A., additional, Chatzidimitriou, Dimitrios, additional, Vasiliou, Vasilis, additional, and Vizirianakis, Ioannis S., additional

Published
2024
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9. Genetic justification of severe COVID-19 using a rigorous algorithm

Author

Gavriilaki, Eleni, Asteris, Panagiotis G., Touloumenidou, Tasoula, Koravou, Evaggelia-Evdoxia, Koutra, Maria, Papayanni, Penelope Georgia, Karali, Vassiliki, Papalexandri, Apostolia, Varelas, Christos, Chatzopoulou, Fani, Chatzidimitriou, Maria, Chatzidimitriou, Dimitrios, Veleni, Anastasia, Grigoriadis, Savvas, Rapti, Evdoxia, Chloros, Diamantis, Kioumis, Ioannis, Kaimakamis, Evaggelos, Bitzani, Milly, Boumpas, Dimitrios, Tsantes, Argyris, Sotiropoulos, Damianos, Sakellari, Ioanna, Kalantzis, Ioannis G., Parastatidis, Stefanos T., Koopialipoor, Mohammadreza, Cavaleri, Liborio, Armaghani, Danial J., Papadopoulou, Anastasia, Brodsky, Robert Alan, Kokoris, Styliani, and Anagnostopoulos, Achilles

Published
2021
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10. Global and regional epidemiology of HIV-1 recombinants in 1990–2015: a systematic review and global survey

Author

Abimiku, Alash'le G, Agwale, Simon, Archibald, Chris, Avidor, Boaz, Barbás, María Gabriela, Barre-Sinoussi, Francoise, Barugahare, Banson, Belabbes, El Hadj, Bertagnolio, Silvia, Birx, Deborah, Bobkov, Aleksei F, Brandful, James, Bredell, Helba, Brennan, Catherine A, Brooks, James, Bruckova, Marie, Buonaguro, Luigi, Buonaguro, Franco, Buttò, Stefano, Buvé, Anne, Campbell, Mary, Carr, Jean, Carrera, Alex, Carrillo, Manuel Gómez, Celum, Connie, Chaplin, Beth, Charles, Macarthur, Chatzidimitriou, Dimitrios, Chen, Zhiwei, Chijiwa, Katsumi, Cooper, David, Cunningham, Philip, Dagnra, Anoumou, de Gascun, Cillian F, Del Amo, Julia, Delgado, Elena, Dietrich, Ursula, Dwyer, Dominic, Ellenberger, Dennis, Ensoli, Barbara, Essex, Max, Gao, Feng, Fleury, Hervé, Fonjungo, Peter N, Foulongne, Vincent, Gadkari, Deepak A, García, Federico, Garsia, Roger, Gershy-Damet, Guy Michel, Glynn, Judith R, Goodall, Ruth, Grossman, Zehava, Lindenmeyer-Guimarães, Monick, Hahn, Beatrice, Hamers, Raph L, Hamouda, Osamah, Handema, Ray, He, Xiang, Herbeck, Joshua, Ho, David D, Holguin, Africa, Hosseinipour, Mina, Hunt, Gillian, Ito, Masahiko, Bel Hadj Kacem, Mohamed Ali, Kahle, Erin, Kaleebu, Pontiano, Kalish, Marcia, Kamarulzaman, Adeeba, Kang, Chun, Kanki, Phyllis, Karamov, Edward, Karasi, Jean-Claude, Kayitenkore, Kayitesi, Kelleher, Tony, Kitayaporn, Dwip, Kostrikis, Leondios G, Kucherer, Claudia, Lara, Claudia, Leitner, Thomas, Liitsola, Kirsi, Lingappa, Jai, Linka, Marek, Lorenzana de Rivera, Ivette, Lukashov, Vladimir, Maayan, Shlomo, Mayr, Luzia, McCutchan, Francine, Meda, Nicolas, Menu, Elisabeth, Mhalu, Fred, Mloka, Doreen, Mokili, John L, Montes, Brigitte, Mor, Orna, Morgado, Mariza, Mosha, Fausta, Moussi, Awatef, Mullins, James, Najera, Rafael, Nasr, Mejda, Ndembi, Nicaise, Neilson, Joel R, Nerurkar, Vivek R, Neuhann, Florian, Nolte, Claudine, Novitsky, Vlad, Nyambi, Philippe, Ofner, Marianna, Paladin, Fem J, Papa, Anna, Pape, Jean, Parkin, Neil, Parry, Chris, Peeters, Martine, Pelletier, Alexandra, Pérez-Álvarez, Lucía, Pillay, Deenan, Pinto, Angie, Quang, Trinh Duy, Rademeyer, Cecilia, Raikanikoda, Filimone, Rayfield, Mark A, Reynes, Jean-Marc, Rinke de Wit, Tobias, Robbins, Kenneth E, Rolland, Morgane, Rousseau, Christine, Salazar-Gonzales, Jesus, Salem, Hanan, Salminen, Mika, Salomon, Horacio, Sandstrom, Paul, Santiago, Mario L, Sarr, Abdoulaye D, Schroeder, Bryan, Segondy, Michel, Selhorst, Philippe, Sempala, Sylvester, Servais, Jean, Shaik, Ansari, Shao, Yiming, Slim, Amine, Soares, Marcelo A, Songok, Elijah, Stewart, Debbie, Stokes, Julie, Subbarao, Shambavi, Sutthent, Ruengpung, Takehisa, Jun, Tanuri, Amilcar, Tee, Kok Keng, Thapa, Kiran, Thomson, Michael, Tran, Tyna, Urassa, Willy, Ushijima, Hiroshi, van de Perre, Philippe, van der Groen, Guido, van Laethem, Kristel, van Oosterhout, Joep, van Sighem, Ard, van Wijngaerden, Eric, Vandamme, Anne-Mieke, Vercauteren, Jurgen, Vidal, Nicole, Wallace, Lesley, Williamson, Carolyn, Wolday, Dawit, Xu, Jianqing, Yang, Chunfu, Zhang, Linqi, Zhang, Rong, Hemelaar, Joris, Elangovan, Ramyiadarsini, Yun, Jason, Dickson-Tetteh, Leslie, Kirtley, Shona, Gouws-Williams, Eleanor, and Ghys, Peter D

Published
2020
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12. The GEnetic Syntax Score: a genetic risk assessment implementation tool grading the complexity of coronary artery disease—rationale and design of the GESS study

Author

Vizirianakis, Ioannis S., Chatzopoulou, Fani, Papazoglou, Andreas S., Karagiannidis, Efstratios, Sofidis, Georgios, Stalikas, Nikolaos, Stefopoulos, Christos, Kyritsis, Konstantinos A., Mittas, Nikolaos, Theodoroula, Nikoleta F., Lampri, Aggeliki, Mezarli, Eleni, Kartas, Anastasios, Chatzidimitriou, Dimitrios, Papa-Konidari, Anna, Angelis, Eleftherios, Karvounis, Ηaralambos, and Sianos, Georgios

Published
2021
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13. Correction to: The GEnetic Syntax Score: a genetic risk assessment implementation tool grading the complexity of coronary artery disease—rationale and design of the GESS study

Author

Vizirianakis, Ioannis S., Chatzopoulou, Fani, Papazoglou, Andreas S., Karagiannidis, Efstratios, Sofdis, Georgios, Stalikas, Nikolaos, Stefopoulos, Christos, Kyritsis, Konstantinos A., Mittas, Nikolaos, Theodoroula, Nikoleta F., Lampri, Aggeliki, Mezarli, Eleni, Kartas, Anastasios, Chatzidimitriou, Dimitrios, Papa-Konidari, Anna, Angelis, Eleftherios, Karvounis, Ηaralambos, and Sianos, Georgios

Published
2021
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14. Awareness, knowledge and trust in the Greek authorities towards COVID-19 pandemic: results from the Epirus Health Study cohort

Author

Kanellopoulou, Afroditi, Koskeridis, Fotios, Markozannes, Georgios, Bouras, Emmanouil, Soutziou, Chrysa, Chaliasos, Konstantinos, Doumas, Michail T., Sigounas, Dimitrios E., Tzovaras, Vasilios T., Panos, Agapios, Stergiou, Yiolanda, Mellou, Kassiani, Papamichail, Dimitrios, Aretouli, Eleni, Chatzidimitriou, Dimitrios, Chatzopoulou, Fani, Bairaktari, Eleni, Tzoulaki, Ioanna, Evangelou, Evangelos, Rizos, Evangelos C., Ntzani, Evangelia, Vakalis, Konstantinos, and Tsilidis, Konstantinos K.

Published
2021
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15. Global and regional molecular epidemiology of HIV-1, 1990–2015: a systematic review, global survey, and trend analysis

Author

Abimiku, Alash'le G, Agwale, Simon, Archibald, Chris, Avidor, Boaz, Barbás, María Gabriela, Barre-Sinoussi, Francoise, Barugahare, Banson, Belabbes, El Hadj, Bertagnolio, Silvia, Birx, Deborah, Bobkov, Aleksei F, Brandful, James, Bredell, Helba, Brennan, Catherine A, Brooks, James, Bruckova, Marie, Buonaguro, Luigi, Buonaguro, Franco, Buttò, Stefano, Buve, Anne, Campbell, Mary, Carr, Jean, Carrera, Alex, Carrillo, Manuel Gómez, Celum, Connie, Chaplin, Beth, Charles, Macarthur, Chatzidimitriou, Dimitrios, Chen, Zhiwei, Chijiwa, Katsumi, Cooper, David, Cunningham, Philip, Dagnra, Anoumou, de Gascun, Cillian F, Del Amo, Julia, Delgado, Elena, Dietrich, Ursula, Dwyer, Dominic, Ellenberger, Dennis, Ensoli, Barbara, Essex, Max, Gao, Feng, Fleury, Herve, Fonjungo, Peter N, Foulongne, Vincent, Gadkari, Deepak A, García, Federico, Garsia, Roger, Gershy-Damet, Guy Michel, Glynn, Judith R, Goodall, Ruth, Grossman, Zehava, Lindenmeyer-Guimarães, Monick, Hahn, Beatrice, Hamers, Raph L, Hamouda, Osamah, Handema, Ray, He, Xiang, Herbeck, Joshua, Ho, David D, Holguin, Africa, Hosseinipour, Mina, Hunt, Gillian, Ito, Masahiko, Bel Hadj Kacem, Mohamed Ali, Kahle, Erin, Kaleebu, Pontiano Kaleebu, Kalish, Marcia, Kamarulzaman, Adeeba, Kang, Chun, Kanki, Phyllis, Karamov, Edward, Karasi, Jean-Claude, Kayitenkore, Kayitesi, Kelleher, Tony, Kitayaporn, Dwip, Kostrikis, Leondios G, Kucherer, Claudia, Lara, Claudia, Leitner, Thomas, Liitsola, Kirsi, Lingappa, Jai, Linka, Marek, Lorenzana de Rivera, Ivette, Lukashov, Vladimir, Maayan, Shlomo, Mayr, Luzia, McCutchan, Francine, Meda, Nicolas, Menu, Elisabeth, Mhalu, Fred, Mloka, Doreen, Mokili, John L, Montes, Brigitte, Mor, Orna, Morgado, Mariza, Mosha, Fausta, Moussi, Awatef, Mullins, James, Najera, Rafael, Nasr, Mejda, Ndembi, Nicaise, Neilson, Joel R, Nerurkar, Vivek R, Neuhann, Florian, Nolte, Claudine, Novitsky, Vlad, Nyambi, Philippe, Ofner, Marianna, Paladin, Fem J, Papa, Anna, Pape, Jean, Parkin, Neil, Parry, Chris, Peeters, Martine, Pelletier, Alexandra, Pérez-Álvarez, Lucía, Pillay, Deenan, Pinto, Angie, Quang, Trinh Duy, Rademeyer, Cecilia, Raikanikoda, Filimone, Rayfield, Mark A, Reynes, Jean-Marc, Rinke de Wit, Tobias, Robbins, Kenneth E, Rolland, Morgane, Rousseau, Christine, Salazar-Gonzales, Jesus, Salem, Hanan, Salminen, Mika, Salomon, Horacio, Sandstrom, Paul, Santiago, Mario L, Sarr, Abdoulaye D, Schroeder, Bryan, Segondy, Michel, Selhorst, Philippe, Sempala, Sylvester, Servais, Jean, Shaik, Ansari, Shao, Yiming, Slim, Amine, Soares, Marcelo A, Songok, Elijah, Stewart, Debbie, Stokes, Julie, Subbarao, Shambavi, Sutthent, Ruengpung, Takehisa, Jun, Tanuri, Amilcar, Tee, Kok Keng, Thapa, Kiran, Thomson, Michael, Tran, Tyna, Urassa, Willy, Ushijima, Hiroshi, van de Perre, Philippe, van der Groen, Guido, van Laethem, Kristel, van Oosterhout, Joep, van Sighem, Ard, van Wijngaerden, Eric, Vandamme, Anne-Mieke, Vercauteren, Jurgen, Vidal, Nicole, Wallace, Lesley, Williamson, Carolyn, Wolday, Dawit, Xu, Jianqing, Yang, Chunfu, Zhang, Linqi, Zhang, Rong, Hemelaar, Joris, Elangovan, Ramyiadarsini, Yun, Jason, Dickson-Tetteh, Leslie, Fleminger, Isabella, Kirtley, Shona, Williams, Brian, Gouws-Williams, Eleanor, and Ghys, Peter D

Published
2019
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20. Nonreciprocal propagation in a non-Hermitian silicon photonic coupler employing graphene saturable absorption

Author

Chatzidimitriou Dimitrios, Pitilakis Alexandros, Yioultsis Traianos, and Kriezis Emmanouil

Subjects
Physics, QC1-999
Abstract

We present the concept, analysis and design of a nonreciprocal system of coupled nonlinear waveguides, operating at the near infrared. We exploit the spatial asymmetry induced by the exceptional points of a non-Hermitian coupler which, combined with saturable absorption in the nonlinear regime, can break Lorentz reciprocity. In this work, we introduce asymmetric losses in a pair of coupled silicon waveguides by overlaying only one of them with unbiased graphene, subject to saturable absorption. The device can be used as a broadband half-duplex isolator: a two-port component offering unidirectional transmission of high-power signals.

Published
2020
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21. Estimation of the determinants for HIV late presentation using the traditional definition and molecular clock‐inferred dates: Evidence that older age, heterosexual risk group and more recent diagnosis are prognostic factors

Author

Kostaki, Evangelia Georgia, primary, Limnaios, Stefanos, additional, Adamis, Georgios, additional, Xylomenos, Georgios, additional, Chini, Maria, additional, Mangafas, Nikos, additional, Lazanas, Marios, additional, Patrinos, Stavros, additional, Metallidis, Simeon, additional, Tsachouridou, Olga, additional, Papastamopoulos, Vasileios, additional, Chatzidimitriou, Dimitrios, additional, Antoniadou, Anastasia, additional, Papadopoulos, Antonios, additional, Protopapas, Konstantinos, additional, Tsiara, Chrysa, additional, Psichogiou, Mina, additional, Basoulis, Dimitrios, additional, Pilalas, Dimitrios, additional, Paraskeva, Dimitra, additional, Chrysos, Georgios, additional, Paparizos, Vasileios, additional, Kourkounti, Sofia, additional, Sambatakou, Helen, additional, Bolanos, Vasileios, additional, Sipsas, Nikolaos V., additional, Lada, Malvina, additional, Barbounakis, Emmanouil, additional, Kantzilaki, Evrikleia, additional, Panagopoulos, Periklis, additional, Petrakis, Vasilis, additional, Drimis, Stelios, additional, Katsarolis, Ioannis, additional, Lagiou, Pagona, additional, Hatzakis, Angelos, additional, Magiorkinis, Gkikas, additional, Skoura, Lemonia, additional, and Paraskevis, Dimitrios, additional

Published
2022
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24. Pathology in Practice

Author

Marouda, Christina, primary, Meletis, Georgios, additional, Saridaki, Eleftheria, additional, Sfougkataki, Theodosia, additional, and Chatzidimitriou, Dimitrios, additional

Published
2022
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26. Immune Response of Adult Sickle Cell Disease Patients after COVID-19 Vaccination: The Experience of a Greek Center

Author

Varelas, Christos, primary, Gavriilaki, Eleni, additional, Sakellari, Ioanna, additional, Klonizakis, Philippos, additional, Koravou, Evaggelia-Evdoxia, additional, Christodoulou, Ioanna, additional, Mavrikou, Ioulia, additional, Kourelis, Andreas, additional, Chatzopoulou, Fani, additional, Chatzidimitriou, Dimitrios, additional, Touloumenidou, Tasoula, additional, Papalexandri, Apostolia, additional, Anagnostopoulos, Achilles, additional, and Vlachaki, Efthimia, additional

Published
2022
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27. Dissecting miRNA–Gene Networks to Map Clinical Utility Roads of Pharmacogenomics-Guided Therapeutic Decisions in Cardiovascular Precision Medicine

Author

Chatzopoulou, Fani, primary, Kyritsis, Konstantinos A., additional, Papagiannopoulos, Christos I., additional, Galatou, Eleftheria, additional, Mittas, Nikolaos, additional, Theodoroula, Nikoleta F., additional, Papazoglou, Andreas S., additional, Karagiannidis, Efstratios, additional, Chatzidimitriou, Maria, additional, Papa, Anna, additional, Sianos, Georgios, additional, Angelis, Lefteris, additional, Chatzidimitriou, Dimitrios, additional, and Vizirianakis, Ioannis S., additional

Published
2022
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28. Genetic prediction of ICU hospitalization and mortality in COVID‐19 patients using artificial neural networks

Author

Asteris, Panagiotis G., primary, Gavriilaki, Eleni, additional, Touloumenidou, Tasoula, additional, Koravou, Evaggelia‐Evdoxia, additional, Koutra, Maria, additional, Papayanni, Penelope Georgia, additional, Pouleres, Alexandros, additional, Karali, Vassiliki, additional, Lemonis, Minas E., additional, Mamou, Anna, additional, Skentou, Athanasia D., additional, Papalexandri, Apostolia, additional, Varelas, Christos, additional, Chatzopoulou, Fani, additional, Chatzidimitriou, Maria, additional, Chatzidimitriou, Dimitrios, additional, Veleni, Anastasia, additional, Rapti, Evdoxia, additional, Kioumis, Ioannis, additional, Kaimakamis, Evaggelos, additional, Bitzani, Milly, additional, Boumpas, Dimitrios, additional, Tsantes, Argyris, additional, Sotiropoulos, Damianos, additional, Papadopoulou, Anastasia, additional, Kalantzis, Ioannis G., additional, Vallianatou, Lydia A., additional, Armaghani, Danial J., additional, Cavaleri, Liborio, additional, Gandomi, Amir H., additional, Hajihassani, Mohsen, additional, Hasanipanah, Mahdi, additional, Koopialipoor, Mohammadreza, additional, Lourenço, Paulo B., additional, Samui, Pijush, additional, Zhou, Jian, additional, Sakellari, Ioanna, additional, Valsami, Serena, additional, Politou, Marianna, additional, Kokoris, Styliani, additional, and Anagnostopoulos, Achilles, additional

Published
2022
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29. A Risk-Stratification Machine Learning Framework for the Prediction of Coronary Artery Disease Severity: Insights From the GESS Trial

Author

Mittas, Nikolaos, primary, Chatzopoulou, Fani, additional, Kyritsis, Konstantinos A., additional, Papagiannopoulos, Christos I., additional, Theodoroula, Nikoleta F., additional, Papazoglou, Andreas S., additional, Karagiannidis, Efstratios, additional, Sofidis, Georgios, additional, Moysidis, Dimitrios V., additional, Stalikas, Nikolaos, additional, Papa, Anna, additional, Chatzidimitriou, Dimitrios, additional, Sianos, Georgios, additional, Angelis, Lefteris, additional, and Vizirianakis, Ioannis S., additional

Published
2022
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30. Dating the Origin and Estimating the Transmission Rates of the Major HIV-1 Clusters in Greece: Evidence about the Earliest Subtype A1 Epidemic in Europe

Author

Limnaios, Stefanos, primary, Kostaki, Evangelia Georgia, additional, Adamis, Georgios, additional, Astriti, Myrto, additional, Chini, Maria, additional, Mangafas, Nikos, additional, Lazanas, Marios, additional, Patrinos, Stavros, additional, Metallidis, Simeon, additional, Tsachouridou, Olga, additional, Papastamopoulos, Vasileios, additional, Kakalou, Eleni, additional, Chatzidimitriou, Dimitrios, additional, Antoniadou, Anastasia, additional, Papadopoulos, Antonios, additional, Psichogiou, Mina, additional, Basoulis, Dimitrios, additional, Gova, Maria, additional, Pilalas, Dimitrios, additional, Paraskeva, Dimitra, additional, Chrysos, Georgios, additional, Paparizos, Vasileios, additional, Kourkounti, Sofia, additional, Sambatakou, Helen, additional, Bolanos, Vasileios, additional, Sipsas, Nikolaos V., additional, Lada, Malvina, additional, Barbounakis, Emmanouil, additional, Kantzilaki, Evrikleia, additional, Panagopoulos, Periklis, additional, Maltezos, Efstratios, additional, Drimis, Stelios, additional, Sypsa, Vana, additional, Lagiou, Pagona, additional, Magiorkinis, Gkikas, additional, Hatzakis, Angelos, additional, Skoura, Lemonia, additional, and Paraskevis, Dimitrios, additional

Published
2022
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32. Humoral and T Cell Immune Responses to Sars-Cov-2 Vaccination in Hematopoietic Cell Transplant Recipients

Author

Gavriilaki, Eleni, primary, Papadopoulou, Anastasia, additional, Touloumenidou, Tasoula, additional, Stavridou, Fani, additional, Koravou, Evdoxia, additional, Giannaki, Maria, additional, Papalexandri, Apostolia, additional, Karavalakis, Georgios, additional, Batsis, Ioannis, additional, Kourelis, Andreas, additional, Chatzopoulou, Fani, additional, Chatzidimitriou, Dimitrios, additional, Sotiropoulos, Damianos, additional, Yannaki, Evangelia, additional, Sakellari, Ioanna, additional, and Anagnostopoulos, Achilles, additional

Published
2021
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34. Molecular Epidemiology of SARS-CoV-2 in Greece Reveals Low Rates of Onward Virus Transmission after Lifting of Travel Restrictions Based on Risk Assessment during Summer 2020

Author

Kostaki, Evangelia Georgia, primary, Pavlopoulos, Georgios A., additional, Verrou, Kleio-Maria, additional, Ampatziadis-Michailidis, Giannis, additional, Harokopos, Vaggelis, additional, Hatzis, Pantelis, additional, Moulos, Panagiotis, additional, Siafakas, Nikolaos, additional, Pournaras, Spyridon, additional, Hadjichristodoulou, Christos, additional, Chatzopoulou, Fani, additional, Chatzidimitriou, Dimitrios, additional, Panagopoulos, Periklis, additional, Lourida, Panagiota, additional, Argyraki, Aikaterini, additional, Lytras, Theodoros, additional, Sapounas, Spyros, additional, Gerolymatos, Gerasimos, additional, Panagiotakopoulos, Georgios, additional, Prezerakos, Panagiotis, additional, Tsiodras, Sotirios, additional, Sypsa, Vana, additional, Hatzakis, Angelos, additional, Anastassopoulou, Cleo, additional, Spanakis, Nikolaos, additional, Tsakris, Athanasios, additional, Dimopoulos, Meletios Athanasios, additional, Kotanidou, Anastasia, additional, Sfikakis, Petros, additional, Kollias, Georgios, additional, Magiorkinis, Gkikas, additional, and Paraskevis, Dimitrios, additional

Published
2021
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36. Additional file 1 of Awareness, knowledge and trust in the Greek authorities towards COVID-19 pandemic: results from the Epirus Health Study cohort

Author

Kanellopoulou, Afroditi, Koskeridis, Fotios, Markozannes, Georgios, Bouras, Emmanouil, Soutziou, Chrysa, Chaliasos, Konstantinos, Doumas, Michail T., Sigounas, Dimitrios E., Tzovaras, Vasilios T., Panos, Agapios, Stergiou, Yiolanda, Mellou, Kassiani, Papamichail, Dimitrios, Aretouli, Eleni, Chatzidimitriou, Dimitrios, Chatzopoulou, Fani, Bairaktari, Eleni, Tzoulaki, Ioanna, Evangelou, Evangelos, Rizos, Evangelos C., Ntzani, Evangelia, Vakalis, Konstantinos, and Tsilidis, Konstantinos K.

Abstract

Additional file 1: Supplementary Figure 1. Categorization of the levels of knowledge regarding the COVID-19 pandemic in Epirus Health Study (EHS).

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2021
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37. Country Level Diversity of the HIV-1 Pandemic between 1990 and 2015

Author

Hemelaar, Joris, Loganathan, Shanghavie, Elangovan, Ramyiadarsini, Yun, Jason, Dickson-Tetteh, Leslie, Kirtley, Shona, Abimiku, Alash’le G., Agwale, Simon, Archibald, Chris, Avidor, Boaz, Barbás, María Gabriela, Barre-Sinoussi, Francoise, Barugahare, Banson, Belabbes, El Hadj, Bertagnolio, Silvia, Birx, Deborah, Bobkov, Aleksei F., Brandful, James, Bredell, Helba, Brennan, Catherine A., Brooks, James, Bruckova, Marie, Buonaguro, Luigi, Buonaguro, Franco, Buttò, Stefano, Buvé, Anne, Campbell, Mary, Carr, Jean, Carrera, Alex, Carrillo, Manuel G. mez, Celum, Connie, Chaplin, Beth, Charles, Macarthur, Chatzidimitriou, Dimitrios, Chen, Zhiwei, Chijiwa, Katsumi, Cooper, David, Cunningham, Philip, Dagnra, Anoumou, de Gascun, Cillian F., del Amo, Julia, Delgado, Elena, Dietrich, Ursula, Dwyer, Dominic, Ellenberger, Dennis, Ensoli, Barbara, Essex, Max, Hamers, Raph L., Loukachov, Vladimir, Rinke de Wit, Tobias, Global Health, AII - Infectious diseases, APH - Personalized Medicine, APH - Quality of Care, Graduate School, and Experimental Immunology

Subjects
medicine.medical_specialty, Unique recombinant form, Genotype, URF, Immunology, HIV Infections, Drug resistance, Biology, Global Health, Microbiology, Circulating recombinant form, 03 medical and health sciences, Diversity index, 0302 clinical medicine, Virology, Pandemic, Epidemiology, Global health, medicine, Humans, 030212 general & internal medicine, HIV vaccine, Pandemics, 030304 developmental biology, Recombination, Genetic, Diversity, 0303 health sciences, Recombinant, Molecular epidemiology, Genetic Variation, HIV, virus diseases, CRF, Cross-Sectional Studies, Genetic Diversity and Evolution, Insect Science, HIV-1, Viral load, Demography
Abstract

Background: The global diversity of HIV forms a major challenge to the development of an HIV vaccine, as well as diagnostic, drug resistance, and viral load assays, which are essential to reaching the UNAIDS 90:90:90 targets. We sought to determine country-level HIV-1 diversity globally during 1990-2015.Methods: We assembled a global HIV-1 molecular epidemiology database through a systematic literature search and a global survey. We searched PubMed, EMBASE (Ovid), CINAHL (Ebscohost), and Global Health (Ovid) for HIV-1 subtyping studies published from Jan 1, 1990, to Dec 31, 2015. We collected additional unpublished data through a global survey of experts. Prevalence studies with original HIV-1 subtyping data collected during 1990-2015 were included. This resulted in a database with 383 519 subtyped HIV-1 samples from 116 countries over four time periods (1990-99, 2000-04, 2005-09 and 2010-15). We analysed country-specific numbers of distinct HIV-1 subtypes, circulating recombinant forms (CRFs), and unique recombinant forms (URFs) in each time period. We also analysed country-specific proportions of infections due to HIV-1 recombinants, CRFs, and URFs and calculated the Shannon Diversity Index for each country. Finally, we analysed global temporal trends in each of these measures of HIV-1 diversity.Results: We found extremely wide variation in complexity of country-level HIV diversity around the world. Central African countries such as Chad, Democratic Republic of the Congo, Angola and Republic of the Congo have the most diverse HIV epidemics. The number of distinct HIV-1 subtypes and recombinants was greatest in Western Europe (Spain and France) and North America (USA) (up to 39 distinct HIV-1 variants in Spain). The proportion of HIV-1 infections due to recombinants was highest in South-East Asia (>95% of infections in Viet Nam, Cambodia, and Thailand), China and West and Central Africa, mainly due to high proportions of CRF01_AE and CRF02_AG. Other CRFs played major roles (>75% of HIV-1 infections) in Estonia (CRF06_cpx), Iran (CRF35_AD), and Algeria (CRF06_cpx). The highest proportions of URFs (>30%) were found in Myanmar, Republic of the Congo and Argentina. Global temporal analysis showed consistent increases over time in country-level numbers of distinct HIV-1 variants and proportions of CRFs and URFs, leading to increases in country-level HIV-1 diversity.Conclusion: Our study provides epidemiological evidence that the HIV pandemic is diversifying at country-level and highlights the increasing challenge to prevention and treatment efforts. HIV-1 molecular epidemiological surveillance needs to be continued and improved.IMPORTANCE Global HIV diversity forms a major challenge to the development of an HIV vaccine, as well as diagnostic, drug resistance, and viral load assays, which are essential to reaching the UNAIDS 90:90:90 targets. This is the first study to analyse global country-level HIV-1 diversity during 1990-2015. We found extremely wide variation in complexity of country-level HIV diversity around the world. Central African countries have the most diverse HIV epidemics. The number of distinct HIV-1 subtypes and recombinants was greatest in Western Europe and North America. The proportion of HIV-1 infections due to recombinants was highest in South-East Asia, China and West and Central Africa. The highest proportions of URFs were found in Myanmar, Republic of the Congo and Argentina. Our study provides epidemiological evidence that the HIV pandemic is diversifying at country-level and highlights the increasing challenge to HIV vaccine development, and diagnostic, drug resistance, and viral load assays.

Published
2020

39. Circulating microRNAs Related to Bone Metabolism in HIV-Associated Bone Loss

Author

Yavropoulou, Maria P., primary, Kolynou, Artemis, additional, Makras, Polyzois, additional, Pikilidou, Maria, additional, Nanoudis, Sideris, additional, Skoura, Lemonia, additional, Tsachouridou, Olga, additional, Ntritsos, Georgios, additional, Tzallas, Alexandros, additional, Tsalikakis, Dimitrios G., additional, Tsave, Olga, additional, Metallidis, Simeon, additional, and Chatzidimitriou, Dimitrios, additional

Published
2021
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44. Awareness, knowledge and trust in the Greek authorities towards COVID-19 pandemic: results from the Epirus Health Study cohort

Author

Kanellopoulou, Afroditi, primary, Koskeridis, Fotios, additional, Markozannes, Georgios, additional, Bouras, Emmanouil, additional, Soutziou, Chrysa, additional, Chaliasos, Konstantinos, additional, Doumas, Michail T, additional, Sigounas, Dimitrios E, additional, Tzovaras, Vasilios T, additional, Panos, Agapios, additional, Stergiou, Yiolanda, additional, Mellou, Kassiani, additional, Papamichail, Dimitrios, additional, Aretouli, Eleni, additional, Chatzidimitriou, Dimitrios, additional, Chatzopoulou, Fani, additional, Bairaktari, Eleni, additional, Tzoulaki, Ioanna, additional, Evangelou, Evangelos, additional, Rizos, Evangelos C, additional, Ntzani, Evangelia, additional, Vakalis, Konstantinos, additional, and Tsilidis, Konstantinos K, additional

Published
2020
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45. Thrombotic Microangiopathy Variants Are Independently Associated with Critical Disease in COVID-19 Patients

Author

Gavriilaki, Eleni, primary, Kokoris, Styliani, additional, Touloumenidou, Tasoula, additional, Koravou, Evdoxia, additional, Koutra, Maria, additional, Karali, Vassiliki, additional, Papalexandri, Lila, additional, Chatzopoulou, Fani, additional, Chatzidimitriou, Maria, additional, Chatzidimitriou, Dimitrios, additional, Veleni, Anastasia, additional, Grigoriadis, Savvas, additional, Konstantinidou, Eulampia, additional, Chloros, Diamantis, additional, Kioumis, Ioannis, additional, Kaimakamis, Evaggelos, additional, Bitzani, Milly, additional, Boumpas, Dimitrios, additional, Tsantes, Argyrios, additional, Sotiropoulos, Damianos, additional, Sakellari, Ioanna, additional, and Anagnostopoulos, Achilles, additional

Published
2020
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46. Global and regional epidemiology of HIV-1 recombinants in 1990–2015: a systematic review and global survey

Author

Hemelaar, Joris, primary, Elangovan, Ramyiadarsini, additional, Yun, Jason, additional, Dickson-Tetteh, Leslie, additional, Kirtley, Shona, additional, Gouws-Williams, Eleanor, additional, Ghys, Peter D, additional, Abimiku, Alash'le G, additional, Agwale, Simon, additional, Archibald, Chris, additional, Avidor, Boaz, additional, Barbás, María Gabriela, additional, Barre-Sinoussi, Francoise, additional, Barugahare, Banson, additional, Belabbes, El Hadj, additional, Bertagnolio, Silvia, additional, Birx, Deborah, additional, Bobkov, Aleksei F, additional, Brandful, James, additional, Bredell, Helba, additional, Brennan, Catherine A, additional, Brooks, James, additional, Bruckova, Marie, additional, Buonaguro, Luigi, additional, Buonaguro, Franco, additional, Buttò, Stefano, additional, Buvé, Anne, additional, Campbell, Mary, additional, Carr, Jean, additional, Carrera, Alex, additional, Carrillo, Manuel Gómez, additional, Celum, Connie, additional, Chaplin, Beth, additional, Charles, Macarthur, additional, Chatzidimitriou, Dimitrios, additional, Chen, Zhiwei, additional, Chijiwa, Katsumi, additional, Cooper, David, additional, Cunningham, Philip, additional, Dagnra, Anoumou, additional, de Gascun, Cillian F, additional, Del Amo, Julia, additional, Delgado, Elena, additional, Dietrich, Ursula, additional, Dwyer, Dominic, additional, Ellenberger, Dennis, additional, Ensoli, Barbara, additional, Essex, Max, additional, Gao, Feng, additional, Fleury, Hervé, additional, Fonjungo, Peter N, additional, Foulongne, Vincent, additional, Gadkari, Deepak A, additional, García, Federico, additional, Garsia, Roger, additional, Gershy-Damet, Guy Michel, additional, Glynn, Judith R, additional, Goodall, Ruth, additional, Grossman, Zehava, additional, Lindenmeyer-Guimarães, Monick, additional, Hahn, Beatrice, additional, Hamers, Raph L, additional, Hamouda, Osamah, additional, Handema, Ray, additional, He, Xiang, additional, Herbeck, Joshua, additional, Ho, David D, additional, Holguin, Africa, additional, Hosseinipour, Mina, additional, Hunt, Gillian, additional, Ito, Masahiko, additional, Bel Hadj Kacem, Mohamed Ali, additional, Kahle, Erin, additional, Kaleebu, Pontiano, additional, Kalish, Marcia, additional, Kamarulzaman, Adeeba, additional, Kang, Chun, additional, Kanki, Phyllis, additional, Karamov, Edward, additional, Karasi, Jean-Claude, additional, Kayitenkore, Kayitesi, additional, Kelleher, Tony, additional, Kitayaporn, Dwip, additional, Kostrikis, Leondios G, additional, Kucherer, Claudia, additional, Lara, Claudia, additional, Leitner, Thomas, additional, Liitsola, Kirsi, additional, Lingappa, Jai, additional, Linka, Marek, additional, Lorenzana de Rivera, Ivette, additional, Lukashov, Vladimir, additional, Maayan, Shlomo, additional, Mayr, Luzia, additional, McCutchan, Francine, additional, Meda, Nicolas, additional, Menu, Elisabeth, additional, Mhalu, Fred, additional, Mloka, Doreen, additional, Mokili, John L, additional, Montes, Brigitte, additional, Mor, Orna, additional, Morgado, Mariza, additional, Mosha, Fausta, additional, Moussi, Awatef, additional, Mullins, James, additional, Najera, Rafael, additional, Nasr, Mejda, additional, Ndembi, Nicaise, additional, Neilson, Joel R, additional, Nerurkar, Vivek R, additional, Neuhann, Florian, additional, Nolte, Claudine, additional, Novitsky, Vlad, additional, Nyambi, Philippe, additional, Ofner, Marianna, additional, Paladin, Fem J, additional, Papa, Anna, additional, Pape, Jean, additional, Parkin, Neil, additional, Parry, Chris, additional, Peeters, Martine, additional, Pelletier, Alexandra, additional, Pérez-Álvarez, Lucía, additional, Pillay, Deenan, additional, Pinto, Angie, additional, Quang, Trinh Duy, additional, Rademeyer, Cecilia, additional, Raikanikoda, Filimone, additional, Rayfield, Mark A, additional, Reynes, Jean-Marc, additional, Rinke de Wit, Tobias, additional, Robbins, Kenneth E, additional, Rolland, Morgane, additional, Rousseau, Christine, additional, Salazar-Gonzales, Jesus, additional, Salem, Hanan, additional, Salminen, Mika, additional, Salomon, Horacio, additional, Sandstrom, Paul, additional, Santiago, Mario L, additional, Sarr, Abdoulaye D, additional, Schroeder, Bryan, additional, Segondy, Michel, additional, Selhorst, Philippe, additional, Sempala, Sylvester, additional, Servais, Jean, additional, Shaik, Ansari, additional, Shao, Yiming, additional, Slim, Amine, additional, Soares, Marcelo A, additional, Songok, Elijah, additional, Stewart, Debbie, additional, Stokes, Julie, additional, Subbarao, Shambavi, additional, Sutthent, Ruengpung, additional, Takehisa, Jun, additional, Tanuri, Amilcar, additional, Tee, Kok Keng, additional, Thapa, Kiran, additional, Thomson, Michael, additional, Tran, Tyna, additional, Urassa, Willy, additional, Ushijima, Hiroshi, additional, van de Perre, Philippe, additional, van der Groen, Guido, additional, van Laethem, Kristel, additional, van Oosterhout, Joep, additional, van Sighem, Ard, additional, van Wijngaerden, Eric, additional, Vandamme, Anne-Mieke, additional, Vercauteren, Jurgen, additional, Vidal, Nicole, additional, Wallace, Lesley, additional, Williamson, Carolyn, additional, Wolday, Dawit, additional, Xu, Jianqing, additional, Yang, Chunfu, additional, Zhang, Linqi, additional, and Zhang, Rong, additional

Published
2020
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47. A Nationwide Study about the Dispersal Patterns of the Predominant HIV-1 Subtypes A1 and B in Greece: Inference of the Molecular Transmission Clusters

Author

Kostaki, Evangelia Georgia, primary, Gova, Maria, additional, Adamis, Georgios, additional, Xylomenos, Georgios, additional, Chini, Maria, additional, Mangafas, Nikos, additional, Lazanas, Marios, additional, Metallidis, Simeon, additional, Tsachouridou, Olga, additional, Papastamopoulos, Vasileios, additional, Chatzidimitriou, Dimitrios, additional, Kakalou, Eleni, additional, Antoniadou, Anastasia, additional, Papadopoulos, Antonios, additional, Psichogiou, Mina, additional, Basoulis, Dimitrios, additional, Pilalas, Dimitrios, additional, Papageorgiou, Ifigeneia, additional, Paraskeva, Dimitra, additional, Chrysos, Georgios, additional, Paparizos, Vasileios, additional, Kourkounti, Sofia, additional, Sambatakou, Helen, additional, Bolanos, Vasileios, additional, Sipsas, Nikolaos V., additional, Lada, Malvina, additional, Barbounakis, Emmanouil, additional, Kantzilaki, Evrikleia, additional, Panagopoulos, Periklis, additional, Petrakis, Vasilis, additional, Drimis, Stelios, additional, Gogos, Charalambos, additional, Hatzakis, Angelos, additional, Beloukas, Apostolos, additional, Skoura, Lemonia, additional, and Paraskevis, Dimitrios, additional

Published
2020
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49. Epstein-Barr Encephalitis in a Child with Congenital Human Immunodeficiency Virus Infection: A Case Report Calling for No Forgetfulness

Author

Tsiatsiou, Olga, primary, Papachristou, Savvas, additional, Papadimitriou, Eleni, additional, Michailidou, Elisavet, additional, Chatzidimitriou, Dimitrios, additional, Papa, Anna, additional, Doulioglou, Vai, additional, Karyda, Stavroula, additional, Antachopoulos, Charalampos, additional, and Roilides, Emmanuel, additional

Published
2020
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