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1. Erratum to 'Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor' [Bioorg. Med. Chem. 23 (2015) 4286–4302]

Author: Ronald J. Voll, Michael A. Wassef, Jeffrey S. Stehouwer, Clinton D. Kilts, Michael J. Owens, Chase H. Bourke, Susan J Plott, Mark M. Goodman, and Matthew S. Birnbaum
Subjects: chemistry.chemical_classification, Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Drug Discovery, Crf1 receptor, Pharmaceutical Science, Molecular Medicine, Molecular Biology, Biochemistry, Alkyl
Published: 2020
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2. Synthesis, binding affinity, radiolabeling, and microPET evaluation of 4-(2-substituted-4-substituted)-8-(dialkylamino)-6-methyl-1-substituted-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-ones as ligands for brain corticotropin-releasing factor type-1 (CRF1) receptors

Author: Ronald J. Voll, Clinton D. Kilts, Jeffrey S. Stehouwer, Chase H. Bourke, Mark M. Goodman, and Michael J. Owens
Subjects: Male, Fluorine Radioisotopes, Stereochemistry, Clinical Biochemistry, Aminopyridines, Pharmaceutical Science, Ligands, Heterocyclic Compounds, 2-Ring, Receptors, Corticotropin-Releasing Hormone, Biochemistry, Article, Cell Line, Corticotropin-releasing hormone receptor 1, chemistry.chemical_compound, Amide, Drug Discovery, Animals, Humans, Receptor, Molecular Biology, Brain uptake, Organic Chemistry, Crf1 receptor, Brain, Pet imaging, Peptide Fragments, Macaca fascicularis, chemistry, Positron-Emission Tomography, Pyrazines, Molecular Medicine, Radiopharmaceuticals
Abstract: Compounds 1-14 were synthesized in a search for high-affinity CRF1 receptor ligands that could be radiolabeled with (11)C or (18)F for use as positron emission tomography (PET) radiotracers. Derivatives of 2 were developed which contained amide N-fluoroalkyl substituents. Compounds [(18)F]24 and [(18)F]25 were found to have appropriate lipophilicities of logP7.4=2.2 but microPET imaging with [(18)F]25 demonstrated limited brain uptake.
Published: 2015
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3. SSRI or CRF antagonism partially ameliorate depressive-like behavior after adolescent social defeat

Author: Gretchen N. Neigh, Chase H. Bourke, and Erica R. Glasper
Subjects: Male, Aging, Methylcellulose, Pharmacology, Receptors, Corticotropin-Releasing Hormone, Corticotropin-releasing hormone receptor 1, Social defeat, Behavioral Neuroscience, Fluoxetine, medicine, Animals, Chronic stress, Rats, Wistar, Social Behavior, Behavior, Animal, Depression, Antagonist, Anhedonia, Rats, Anxiety, medicine.symptom, Reuptake inhibitor, Psychology, Selective Serotonin Reuptake Inhibitors, Stress, Psychological, Clinical psychology, medicine.drug
Abstract: Depression and anxiety during adolescence are complex disorders due to persistent effects on physiology and behavior. Selective-serotonin reuptake inhibitors (SSRI) are currently the most widely used pharmacological intervention for depression. Corticotropin-releasing factor one (CRF1) receptor antagonists represent a novel class of compounds that may have efficacy for depressive and anxiety disorders. This study used an animal model of chronic adolescent stress to determine the efficacy of the SSRI fluoxetine, and a novel CRF1 receptor antagonist, GSK876008, on prevention of the behavioral effects of chronic adolescent stress. Male rats were exposed to chronic social defeat stress, fluoxetine, and/or GSK876008 from postnatal day 28-50. Chronic stress-induced depressive-like behaviors were partially attenuated by either concurrent fluoxetine or GSK876008. Fluoxetine blunted body mass gain in the adolescents exposed to chronic stress. The collective data demonstrate similar efficacy between a SSRI and a CRF1 receptor antagonist in the attenuation of stress-induced anhedonia but fewer side effects were observed in those rats treated with the CRF1 receptor antagonist. These data suggest that CRF1 receptor antagonists may be a viable alternative for treatment of depressive behaviors in adolescents.
Published: 2014
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4. Prenatal exposure to escitalopram and/or stress in rats produces limited effects on endocrine, behavioral, or gene expression measures in adult male rats

Author: Gretchen N. Neigh, Zachary N. Stowe, Chase H. Bourke, Darin E. Olson, and Michael J. Owens
Subjects: Male, medicine.medical_specialty, Offspring, Hypothalamus, Citalopram, Toxicology, Hippocampus, Article, Cellular and Molecular Neuroscience, Developmental Neuroscience, Pregnancy, Endocrine Glands, Internal medicine, medicine, Animals, Escitalopram, Behavior, Animal, Stressor, medicine.disease, Rats, Endocrinology, medicine.anatomical_structure, Prenatal stress, Prenatal Exposure Delayed Effects, Antidepressive Agents, Second-Generation, Gestation, Antidepressant, Female, Transcriptome, Psychology, Stress, Psychological, Hypothalamic–pituitary–adrenal axis, medicine.drug
Abstract: Stress and/or antidepressants during pregnancy have been implicated in a wide range of long-term effects in the offspring. We investigated the long-term effects of prenatal stress and/or clinically relevant antidepressant exposure on male adult offspring in a model of the pharmacotherapy of maternal depression. Female Sprague–Dawley rats were implanted with osmotic minipumps that delivered clinically relevant exposure to the antidepressant escitalopram throughout gestation. Subsequently, pregnant females were exposed on gestational days 10–20 to a chronic unpredictable mild stress paradigm. The male offspring were analyzed in adulthood. Baseline physiological measurements were largely unaltered by prenatal manipulations. Behavioral characterization of the male offspring, with or without pre-exposure to an acute stressor, did not reveal any group differences. Prenatal stress exposure resulted in a faster return towards baseline following the peak response to an acute restraint stressor, but not an airpuff startle stressor, in adulthood. Microarray analysis of the hippocampus and hypothalamus comparing all treatment groups revealed no significantly-altered transcripts. Real time PCR of the hippocampus confirmed that several transcripts in the CRFergic, serotonergic, and neural plasticity pathways were unaffected by prenatal exposures. This stress model of maternal depression and its treatment indicate that escitalopram use and/or stress during pregnancy produced no alterations in our measures of male adult behavior or the transcriptome, however prenatal stress exposure resulted in some evidence for increased glucocorticoid negative feedback following an acute restraint stress. Study design should be carefully considered before implications for human health are ascribed to prenatal exposure to stress or antidepressant medication.
Published: 2013
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5. Translational reciprocity: Bridging the gap between preclinical studies and clinical treatment of stress effects on the adolescent brain

Author: Gretchen N. Neigh, Chase H. Bourke, Lorie A. Ritschel, Constance S. Harrell, and Lisa Smith Kilpela
Subjects: Adolescent, Stress effects, General Neuroscience, Early life stress, Brain, medicine.disease, Article, Developmental psychology, Translational Research, Biomedical, Disease Models, Animal, Treatment Outcome, Extant taxon, Risk and resilience, medicine, Animals, Humans, Major depressive disorder, Psychology, Borderline personality disorder, Clinical treatment, Neuroscience, Stress, Psychological, Organism
Abstract: The genetic, biological, and environmental backgrounds of an organism fundamentally influence the balance between risk and resilience to stress. Sex, age, and environment transact with responses to trauma in ways that can mitigate or exacerbate the likelihood that post-traumatic stress disorder will develop. Translational approaches to modeling affective disorders in animals will ultimately provide novel treatments and a better understanding of the neurobiological underpinnings behind these debilitating disorders. The extant literature on trauma/stress has focused predominately on limbic and cortical structures that innervate the hypothalamic-pituitary-adrenal axis and influence glucocorticoid-mediated negative feedback. It is through these neuroendocrine pathways that a self-perpetuating fear memory can propagate the long-term effects of early life trauma. Recent work incorporating translational approaches has provided novel pathways that can be influenced by early life stress, such as the glucocorticoid receptor chaperones, including FKBP51. Animal models of stress have differing effects on behavior and endocrine pathways; however, complete models replicating clinical characteristics of risk and resilience have not been rigorously studied. This review discusses a four-factor model that considers the importance of studying both risk and resilience in understanding the developmental response to trauma/stress. Consideration of the multifactorial nature of clinical populations in the design of preclinical models and the application of preclinical findings to clinical treatment approaches comprise the core of translational reciprocity, which is discussed in the context of the four-factor model.
Published: 2013
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6. Exposure to repeated maternal aggression induces depressive-like behavior and increases startle in adult female rats

Author: Chase H. Bourke and Gretchen N. Neigh
Subjects: Reflex, Startle, Sucrose, Startle response, medicine.medical_specialty, Elevated plus maze, Radioimmunoassay, Estrous Cycle, Article, Open field, Social defeat, Food Preferences, Behavioral Neuroscience, Pregnancy, Internal medicine, medicine, Animals, Chronic stress, Rats, Wistar, Maze Learning, Swimming, Analysis of Variance, medicine.diagnostic_test, Depression, Aggression, Startle reaction, Rats, Endocrinology, Acoustic Stimulation, Maternal Exposure, Sweetening Agents, Female, medicine.symptom, Corticosterone, Psychology, Stress, Psychological, Behavioural despair test
Abstract: The stress response is a multifaceted physiological reaction that engages a wide range of systems. Animal studies examining stress and the stress response employ diverse methods as stressors. While many of these stressors are capable of inducing a stress response in animals, a need exists for an ethologically relevant stressor for female rats. The purpose of the current study was to use an ethologically relevant social stressor to induce behavioral alterations in adult female rats. Adult (postnatal day 90) female Wistar rats were repeatedly exposed to lactating Long Evans female rats to simulate chronic stress. After six days of sessions, intruder females exposed to defeat were tested in the sucrose consumption test, the forced swim test, acoustic startle test, elevated plus maze, and open field test. At the conclusion of behavioral testing, animals were restrained for 30 minutes and trunk blood was collected for assessment of serum hormones. Female rats exposed to maternal aggression exhibited decreased sucrose consumption, and impaired coping behavior in the forced swim test. Additionally, female rats exposed to repeated maternal aggression exhibited an increased acoustic startle response. No changes were observed in female rats in the elevated plus maze or open field test. Serum hormones were unaltered due to repeated exposure to maternal aggression. These data indicate the importance of the social experience in the development of stress-related behaviors: an acerbic social experience in female rats precipitates the manifestation of depressive-like behaviors and an enhanced startle response.
Published: 2012
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7. Serotonin Transporter Occupancy in Rats Exposed to Serotonin Reuptake Inhibitors In Utero or via Breast Milk

Author: Zachary N. Stowe, Amanda Nemeroff, James C. Ritchie, Catherine F. Capello, Chase H. Bourke, D. Jeffrey Newport, and Michael J. Owens
Subjects: Central Nervous System, Aging, medicine.medical_specialty, Serotonin reuptake inhibitor, Venlafaxine, Anxiety, Motor Activity, Fetus, Neuropharmacology, Pregnancy, Fluoxetine, Internal medicine, Image Processing, Computer-Assisted, medicine, Animals, Rats, Long-Evans, Maternal Behavior, Serotonin Uptake Inhibitors, Maternal-Fetal Exchange, Serotonin transporter, Serotonin Plasma Membrane Transport Proteins, Pharmacology, Sertraline, biology, business.industry, Brain, Infusion Pumps, Implantable, Paroxetine, Rats, Milk, Endocrinology, Motor Skills, Prenatal Exposure Delayed Effects, biology.protein, Molecular Medicine, Antidepressant, Female, business, Selective Serotonin Reuptake Inhibitors, medicine.drug
Abstract: Rigorous data regarding fetal central nervous system (CNS) exposure after antidepressant exposure are sparse. The magnitude of serotonin reuptake inhibitor (SRI) CNS exposure was measured in three groups of rats using ex vivo autoradiography of the serotonin transporter (SERT): 1) in utero, 2) postnatal clearance after birth, and 3) exposure through lactation. Rats were exposed to one of five SRI-type antidepressants (escitalopram, fluoxetine, paroxetine, sertraline, and venlafaxine) administered continuously via osmotic minipumps to pregnant or nursing dams. Dam dosing was adjusted to reflect the 50th and 85th percentiles of serum concentrations observed in pregnant women. Embryonic day 21 rat pups exposed in utero exhibited >80% SERT occupancy in brain tissue, which is equivalent to that of the pregnant dam and similar to that reported for human pharmacotherapy. Venlafaxine was the exception with occupancies ranging from 61 to 92% across different litters. The magnitude of SERT occupancy is essentially equivalent between dams and fetuses. By postnatal day 4, high SERT occupancy was observed only in fluoxetine-exposed pups (41–92% occupancy). Significantly less, but measurable, exposure occurred via breast milk exposure even in the absence of detectable drug concentrations in nursing pup sera. Pups exposed to SRIs via breast milk for 3 or 7 days exhibited varying SERT occupancies (0–57% depending on the individual medication and dam dose). These data highlight the need for animal modeling of fetal and nursing infant drug exposure using clinically meaningful dosing strategies and appropriate CNS measures to develop rational treatment guidelines that systematically minimize fetal and neonatal medication exposure in humans.
Published: 2011
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8. Behavioral effects of chronic adolescent stress are sustained and sexually dimorphic

Author: Chase H. Bourke and Gretchen N. Neigh
Subjects: Dominance-Subordination, Male, Restraint, Physical, Elevated plus maze, medicine.medical_specialty, Adolescent, Physiology, Article, Social defeat, Behavioral Neuroscience, chemistry.chemical_compound, Sex Factors, Endocrinology, Corticosterone, medicine, Animals, Humans, Rats, Long-Evans, Rats, Wistar, Maze Learning, Social Behavior, Psychiatry, Swimming, Sex Characteristics, Endocrine and Autonomic Systems, Stressor, Anhedonia, Rats, chemistry, Adolescent Behavior, Anxiety, Female, Animal studies, medicine.symptom, Psychology, Stress, Psychological, Sex characteristics
Abstract: Evidence suggests that women are more susceptible to stress-related disorders than men. Animal studies demonstrate a similar female sensitivity to stress and have been used to examine the underlying neurobiology of sex-specific effects of stress. Although our understanding of the sex-specific effects of chronic adolescent stress has grown in recent years, few studies have reported the effects of adolescent stress on depressive-like behavior. The purpose of this study was to determine if a chronic mixed modality stressor (consisting of isolation, restraint, and social defeat) during adolescence (PND 37-49) resulted in differential and sustained changes in depressive-like behavior in male and female Wistar rats. Female rats exposed to chronic adolescent stress displayed decreased sucrose consumption, hyperactivity in the elevated plus maze, decreased activity in the forced swim test, and a blunted corticosterone response to an acute forced swim stress compared to controls during both adolescence (PND 48-57) and adulthood (PND 96-104). Male rats exposed to chronic adolescent stress did not manifest significant behavioral changes at either the end of adolescence or in adulthood. These data support the proposition that adolescence may be a stress sensitive period for females and exposure to stress during adolescence results in behavioral effects that persist in females. Studies investigating the sex-specific effects of chronic adolescent stress may lead to a better understanding of the sexually dimorphic incidence of depressive and anxiety disorders in humans and ultimately improve prevention and treatment strategies.
Published: 2011
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9. Prenatal stress-induced increases in hippocampal von Willebrand factor expression are prevented by concurrent prenatal escitalopram

Author: Gretchen N. Neigh, Michael J. Owens, Christina L. Nemeth, Zachary N. Stowe, Sean D. Kelly, Emily E. Hardy, and Chase H. Bourke
Subjects: 0301 basic medicine, Male, medicine.medical_specialty, Hippocampus, Prefrontal Cortex, Experimental and Cognitive Psychology, Citalopram, Article, 03 medical and health sciences, Behavioral Neuroscience, 0302 clinical medicine, Von Willebrand factor, Pregnancy, Internal medicine, von Willebrand Factor, medicine, Escitalopram, Animals, Chronic stress, Angiogenic Proteins, biology, Age Factors, medicine.disease, Amygdala, Rats, 030104 developmental biology, Endocrinology, Prenatal stress, In utero, Prenatal Exposure Delayed Effects, biology.protein, Female, Psychology, Reactive Oxygen Species, 030217 neurology & neurosurgery, Stress, Psychological, medicine.drug
Abstract: Prenatal stress has been linked to deficits in neurological function including deficient social behavior, alterations in learning and memory, impaired stress regulation, and susceptibility to adult disease. In addition, prenatal environment is known to alter cardiovascular health; however, limited information is available regarding the cerebrovascular consequences of prenatal stress exposure. Vascular disturbances late in life may lead to cerebral hypoperfusion which is linked to a variety of neurodegenerative and psychiatric diseases. The known impact of cerebrovascular compromise on neuronal function and behavior highlights the importance of characterizing the impact of stress on not just neurons and glia, but also cerebrovasculature. Von Willebrand factor has previously been shown to be impacted by prenatal stress and is predictive of cerebrovascular health. Here we assess the impact of prenatal stress on von Willebrand factor and related angiogenic factors. Furthermore, we assess the potential protective effects of concurrent anti-depressant treatment during in utero stress exposure on the assessed cerebrovascular endpoints. Prenatal stress augmented expression of von Willebrand factor which was prevented by concurrent in utero escitalopram treatment. The functional implications of this increase in von Willebrand factor remain elusive, but the presented data demonstrate that although prenatal stress did not independently impact total vascularization, exposure to chronic stress in adulthood decreased blood vessel length. In addition, the current study demonstrates that production of reactive oxygen species in the hippocampus is decreased by prenatal exposure to escitalopram. Collectively, these findings demonstrate that the prenatal experience can cause complex changes in adult cerebral vascular structure and function.
Published: 2016

10. Prenatal stress, regardless of concurrent escitalopram treatment, alters behavior and amygdala gene expression of adolescent female rats

Author: Zachary N. Stowe, Courtney A. Sholar, Steven J. Ryan, Gretchen N. Neigh, David E. Ehrlich, Nesha Jairam, Chase H. Bourke, Sydney A. Rowson, Michael J. Owens, Rimi Hazra, Christina L. Nemeth, and Donald G. Rainnie
Subjects: medicine.medical_specialty, Offspring, Gene Expression, Learned helplessness, Citalopram, Anxiety, Amygdala, Article, Rats, Sprague-Dawley, Cellular and Molecular Neuroscience, Pregnancy, Internal medicine, medicine, Escitalopram, Animals, Solute Carrier Family 12, Member 2, gamma-Aminobutyric Acid, Pharmacology, Memory Disorders, Estradiol, Symporters, medicine.disease, Disease Models, Animal, medicine.anatomical_structure, Endocrinology, Prenatal stress, Prenatal Exposure Delayed Effects, Receptor, Serotonin, 5-HT1A, Antidepressant, Female, Psychology, Corticosterone, Selective Serotonin Reuptake Inhibitors, Stress, Psychological, medicine.drug
Abstract: Depression during pregnancy has been linked to in utero stress and is associated with long-lasting symptoms in offspring, including anxiety, helplessness, attentional deficits, and social withdrawal. Depression is diagnosed in 10-20% of expectant mothers, but the impact of antidepressant treatment on offspring development is not well documented, particularly for females. Here, we used a prenatal stress model of maternal depression to test the hypothesis that in utero antidepressant treatment could mitigate the effects of prenatal stress. We also investigated the effects of prenatal stress and antidepressant treatment on gene expression related to GABAergic and serotonergic neurotransmission in the amygdala, which may underlie behavioral effects of prenatal stress. Nulliparous female rats were implanted with osmotic minipumps delivering clinically-relevant concentrations of escitalopram and mated. Pregnant dams were exposed to 12 days of mixed-modality stressors, and offspring were behaviorally assessed in adolescence (postnatal day 28) and adulthood (beyond day 90) to determine the extent of behavioral change. We found that in utero stress exposure, regardless of escitalopram treatment, increased anxiety-like behavior in adolescent females and profoundly influenced amygdala expression of the chloride transporters KCC2 and NKCC1, which regulate GABAergic function. In contrast, prenatal escitalopram exposure alone elevated amygdala expression of 5-HT1A receptors. In adulthood, anxiety-like behavior returned to baseline and gene expression effects in the amygdala abated, whereas deficits emerged in novel object recognition for rats exposed to stress during gestation. These findings suggest prenatal stress causes age-dependent deficits in anxiety-like behavior and amygdala function in female offspring, regardless of antidepressant exposure.
Published: 2015

11. Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor

Author: Chase H. Bourke, Jeffrey S. Stehouwer, Susan J Plott, Ronald J. Voll, Michael A. Wassef, Clinton D. Kilts, Michael J. Owens, Mark M. Goodman, and Matthew S. Birnbaum
Subjects: Male, Fluorine Radioisotopes, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Chemistry Techniques, Synthetic, Ligands, Biochemistry, Binding, Competitive, Receptors, Corticotropin-Releasing Hormone, Article, Corticotropin-releasing hormone receptor 1, Rats, Sprague-Dawley, chemistry.chemical_compound, Diagnostic Uses of Chemicals, Drug Discovery, PEG ratio, medicine, Animals, Humans, Receptor, Molecular Biology, Alkyl, chemistry.chemical_classification, Chemistry, Organic Chemistry, Crf1 receptor, Anatomy, In vitro, Macaca fascicularis, medicine.anatomical_structure, Isotope Labeling, Positron-Emission Tomography, Molecular Medicine, Bone marrow, Radiopharmaceuticals, Fluoride
Abstract: A series of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines were synthesized and evaluated as potential positron emission tomography (PET) tracers for the corticotropin-releasing factor type-1 (CRF1) receptor. Compounds 27, 28, 29, and 30 all displayed high binding affinity (⩽1.2 nM) to the CRF1 receptor when assessed by in vitro competition binding assays at 23 °C, whereas a decrease in affinity (⩾10-fold) was observed with compound 26. The logP7.4 values of [(18)F]26-[(18)F]29 were in the range of ∼2.2-2.8 and microPET evaluation of [(18)F]26-[(18)F]29 in an anesthetized male cynomolgus monkey demonstrated brain penetrance, but specific binding was not sufficient enough to differentiate regions of high CRF1 receptor density from regions of low CRF1 receptor density. Radioactivity uptake in the skull, and sphenoid bone and/or sphenoid sinus during studies with [(18)F]28, [(18)F]28-d8, and [(18)F]29 was attributed to a combination of [(18)F]fluoride generated by metabolic defluorination of the radiotracer and binding of intact radiotracer to CRF1 receptors expressed on mast cells in the bone marrow. Uptake of [(18)F]26 and [(18)F]27 in the skull and sphenoid region was rapid but then steadily washed out which suggests that this behavior was the result of binding to CRF1 receptors expressed on mast cells in the bone marrow with no contribution from [(18)F]fluoride.
Published: 2015

12. Corticotropin-Releasing Factor

Author: Karen E. Murray, Chase H. Bourke, and Michael J. Owens
Published: 2015
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13. Prenatal Antidepressant Exposure: Clinical and Preclinical Findings

Author: Chase H. Bourke, Zachary N. Stowe, and Michael J. Owens
Subjects: medicine.medical_specialty, Pediatrics, Offspring, Population, Drug Evaluation, Preclinical, Fetal Development, Pregnancy, medicine, Product Surveillance, Postmarketing, Animals, Humans, education, Psychiatry, Review Articles, Depression (differential diagnoses), Pharmacology, education.field_of_study, Behavior, Animal, business.industry, Clinical study design, medicine.disease, Antidepressive Agents, Prenatal Exposure Delayed Effects, Molecular Medicine, Gestation, Major depressive disorder, Antidepressant, Female, business
Abstract: Pharmacological treatment of any maternal illness during pregnancy warrants consideration of the consequences of the illness and/or medication for both the mother and unborn child. In the case of major depressive disorder, which affects up to 10–20% of pregnant women, the deleterious effects of untreated depression on the offspring can be profound and long lasting. Progress has been made in our understanding of the mechanism(s) of action of antidepressants, fetal exposure to these medications, and serotonin’s role in development. New technologies and careful study designs have enabled the accurate sampling of maternal serum, breast milk, umbilical cord serum, and infant serum psychotropic medication concentrations to characterize the magnitude of placental transfer and exposure through human breast milk. Despite this progress, the extant clinical literature is largely composed of case series, population-based patient registry data that are reliant on nonobjective means and retrospective recall to determine both medication and maternal depression exposure, and limited inclusion of suitable control groups for maternal depression. Conclusions drawn from such studies often fail to incorporate embryology/neurotransmitter ontogeny, appropriate gestational windows, or a critical discussion of statistically versus clinically significant. Similarly, preclinical studies have predominantly relied on dosing models, leading to exposures that may not be clinically relevant. The elucidation of a defined teratological effect or mechanism, if any, has yet to be conclusively demonstrated. The extant literature indicates that, in many cases, the benefits of antidepressant use during pregnancy for a depressed pregnant woman may outweigh potential risks.
Published: 2014

14. Attention Deficit Hyperactivity Disorders: Animal Models

Author: Luis de Lecea, Richard W. Foltin, Harriet de Wit, Verity J. Brown, David C. S. Roberts, Hans Rollema, Husseini K. Manji, David J. Posey, Paul B. S. Clarke, David S. Baldwin, James J. Strain, Megan M. Dahmen, Peter Paul De Deyn, Michael E. Ragozzino, Samuel G. Siris, David S. Tait, Suzanne H. Mitchell, Andrew Young, Jana Lincoln, Seiya Miyamoto, Mei-Chuan Ko, Brian E. Leonard, F. Xavier Castellanos, Linda P. Spear, Bankole A. Johnson, Martin Cammarota, Lisiane Bizarro, Shitij Kapur, Rosa M. M. de Almeida, Tim C. Kirkham, Klaus A. Miczek, Jason C. G. Halford, Andrew Holt, Paul Willner, Gregory D. Stewart, Meghan M. Grady, Tony Dickenson, Charles J. Heyser, Kim Wolff, Marie-Louise G. Wadenberg, Leandro J. Bertoglio, Ingmar H. A. Franken, Heleen B. M. Boos, J. Craig Nelson, Peter A. Santi, Wiepke Cahn, Karl Mann, Shuang Yu, Samuel B. Hutton, Joseph H. Friedman, Yogita Chudasama, Jelena Nesic, Martina de Zwaan, Jill B. Becker, Amee B. Patel, Theodora Duka, Darrell D. Mousseau, Helen J. Cassaday, Charles B. Nemeroff, Patrick M. Sexton, Heather Wilkins, Yesne Alici, Ennio Esposito, Holden D. Brown, Helio Zangrossi, Emil F. Coccaro, Edoardo Spina, Elizabeth C. Warburton, Craig A. Erickson, Falk Kiefer, Michael M. Morgan, Michel Le Moal, A. Richard Green, Andrea Bari, Chase H. Bourke, Matt Field, Michael J. Owens, Christopher L. Cunningham, Joachim D. Uys, William Breitbart, Martin Sarter, Oliver Stiedl, W. Wolfgang Fleischhacker, Hiroyuki Uchida, Tomasz Schneider, James H. Woods, Anne Jackson, Marc N. Potenza, Frederico Guilherme Graeff, Inga D. Neumann, Daniel Hoyer, Kim Fromme, Marilyn E. Carroll, R. H. De Rijk, Becky Kinkead, Daniel Bertrand, Steve Kohut, Michael J. Kuhar, Paul Newhouse, Susan Napier, Peter W. Kalivas, Iván Izquierdo, Micaela Morelli, Samuel R. Chamberlain, Mark Slifstein, E. R. de Kloet, Malcolm Lader, John Atack, Maria Isabel Colado, Grasielle C. Kincheski, Naheed Mirza, Robert L. Balster, Ronald F. Mucha, Peter J. Flor, Warren H. Meck, Debby Van Dam, Glen B. Baker, Stephen M. Stahl, Christine A. Franco, Kieran O’Malley, Sven Ove Ögren, James Winslow, Andreas Marneros, Linda Dykstra, Alfonso Abizaid, Catalin V. Buhusi, Osborne F. X. Almeida, Pedro L. Delgado, Kelly Blankenship, Sharon L. Walsh, Nicola Simola, Jean-Michel Scherrmann, Nuno Sousa, Lucy C. Guillory, H. D. Postma, Lawrence H. Price, Shimon Amir, Philip J. Cowen, Alyson J. Bond, Mitul A. Mehta, Anthony L. Riley, Thomas R. E. Barnes, Jorge A. Quiroz, Raymond S. Hurst, Subhash C. Pandey, Sakire Pogun, Fiona Thomson, Francisco Aboitiz, Christoph Hiemke, Lia R. Bevilaqua, Gorkem Yararbas, Christopher J. McDougle, Antonio Pádua Carobrez, Gail Winger, Barbara J. Mason, Kimberly A. Stigler, Hilde Lavreysen, Barbara J. Sahakian, Sheldon Preskorn, R. Andrew Chambers, Victoria L. Harvey, Roberto William Invernizzi, Arthur Christopoulos, Ximena Carrasco, MacDonald J. Christie, Cecilia J. Hillard, and Tayfun Uzbay
Subjects: medicine.medical_specialty, business.industry, Attention deficit, medicine, Psychiatry, business
Published: 2014
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15. Attention-Deficit and Disruptive Behavior Disorders

Author: F. Xavier Castellanos, Tim C. Kirkham, Karl Mann, Wiepke Cahn, Theodora Duka, David S. Baldwin, James J. Strain, Ennio Esposito, Megan M. Dahmen, David C. S. Roberts, Falk Kiefer, Heleen B. M. Boos, Sheldon Preskorn, Andrew Young, Emil F. Coccaro, Lia R. Bevilaqua, Micaela Morelli, Helio Zangrossi, Shuang Yu, Peter A. Santi, Michael M. Morgan, Frederico Guilherme Graeff, Paul B. S. Clarke, Darrell D. Mousseau, Christine A. Franco, Kieran O’Malley, Susan Napier, Glen B. Baker, Gorkem Yararbas, Samuel G. Siris, Martin Sarter, Christopher L. Cunningham, Malcolm Lader, Daniel Hoyer, Verity J. Brown, Samuel R. Chamberlain, Raymond S. Hurst, Paul Newhouse, Kim Fromme, Jana Lincoln, W. Wolfgang Fleischhacker, R. H. De Rijk, Marc N. Potenza, Subhash C. Pandey, Joachim D. Uys, Thomas R. E. Barnes, Linda P. Spear, Michael E. Ragozzino, Warren H. Meck, Mei-Chuan Ko, Andrea Bari, Marilyn E. Carroll, Andrew Holt, Sakire Pogun, Edoardo Spina, Jason C. G. Halford, R. Andrew Chambers, Debby Van Dam, Michel Le Moal, Gregory D. Stewart, MacDonald J. Christie, Tony Dickenson, Tomasz Schneider, Elizabeth C. Warburton, Martina de Zwaan, Harriet de Wit, Jill B. Becker, Lawrence H. Price, Jelena Nesic, Cecilia J. Hillard, Heather Wilkins, Yesne Alici, Becky Kinkead, Charles J. Heyser, Paul Willner, Daniel Bertrand, Lisiane Bizarro, Yogita Chudasama, David J. Posey, Tayfun Uzbay, Philip J. Cowen, Alyson J. Bond, Rosa M. M. de Almeida, Patrick M. Sexton, J. Craig Nelson, Helen J. Cassaday, Bankole A. Johnson, Martin Cammarota, Mitul A. Mehta, Marie-Louise G. Wadenberg, Amee B. Patel, Chase H. Bourke, Peter Paul De Deyn, Samuel B. Hutton, Michael J. Owens, Christopher J. McDougle, Antonio Pádua Carobrez, Charles B. Nemeroff, Oliver Stiedl, Luis de Lecea, Klaus A. Miczek, Matt Field, Inga D. Neumann, Victoria L. Harvey, Shimon Amir, Joseph H. Friedman, Michael J. Kuhar, John Atack, Shitij Kapur, Sven Ove Ögren, Roberto William Invernizzi, Arthur Christopoulos, Ximena Carrasco, Hiroyuki Uchida, Meghan M. Grady, Leandro J. Bertoglio, Hans Rollema, Robert L. Balster, Husseini K. Manji, Ingmar H. A. Franken, Ronald F. Mucha, Grasielle C. Kincheski, Fiona Thomson, Suzanne H. Mitchell, Peter J. Flor, Gail Winger, Jean-Michel Scherrmann, Naheed Mirza, Peter W. Kalivas, Francisco Aboitiz, William Breitbart, Steve Kohut, Anne Jackson, Christoph Hiemke, Mark Slifstein, Barbara J. Mason, E. R. de Kloet, Maria Isabel Colado, Kimberly A. Stigler, Hilde Lavreysen, Barbara J. Sahakian, Richard W. Foltin, David S. Tait, H. D. Postma, Anthony L. Riley, Seiya Miyamoto, Holden D. Brown, Jorge A. Quiroz, Craig A. Erickson, Linda Dykstra, Kim Wolff, Alfonso Abizaid, James H. Woods, Catalin V. Buhusi, Osborne F. X. Almeida, Pedro L. Delgado, Nuno Sousa, Lucy C. Guillory, Iván Izquierdo, A. Richard Green, Kelly Blankenship, Sharon L. Walsh, Nicola Simola, Stephen M. Stahl, James Winslow, Andreas Marneros, and Brian E. Leonard
Subjects: Disruptive behavior, Attention deficit, Psychology, Humanities
Abstract: Francisco Aboitiz*, F. Xavier Castellanos and Ximena Carrasco Departamento de Psiquiatria, Facultad de Medicina, and Centro Interdisciplinario de Neurociencia, Pontificia Universidad Catolica de Chile, Santiago, Chile New York University Child Study Center, Nathan Kline Institute for Psychiatric Research, New York, NY, USA Servicio de Neurologia y Psiquiatria infantil, Hospital Luis Calvo Mackenna Facultad de Medicina, Universidad de Chile, Santiago, Chile
Published: 2014
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16. Prenatal exposure to escitalopram and/or stress in rats: a prenatal stress model of maternal depression and its treatment

Author: Swati M. Rogers, Zachary N. Stowe, Katherine A. Boss-Williams, Chase H. Bourke, Megan L. Yu, Jay M. Weiss, Catherine F. Capello, and Michael J. Owens
Subjects: medicine.medical_specialty, Light, Physiology, macromolecular substances, Citalopram, Article, Rats, Sprague-Dawley, chemistry.chemical_compound, Corticosterone, Pregnancy, Internal medicine, medicine, Escitalopram, Animals, Maternal Behavior, Depression (differential diagnoses), Pharmacology, Depression, Infusion Pumps, Implantable, Darkness, musculoskeletal system, medicine.disease, Rats, Disease Models, Animal, medicine.anatomical_structure, Endocrinology, chemistry, Prenatal stress, Antidepressant, Female, Psychology, Hypothalamic–pituitary–adrenal axis, Selective Serotonin Reuptake Inhibitors, Stress, Psychological, medicine.drug
Abstract: A rigorously investigated model of stress and antidepressant administration during pregnancy is needed to evaluate possible effects on the mother.The objective of this study was to develop a model of clinically relevant prenatal exposure to an antidepressant and stress during pregnancy to evaluate the effects on maternal care behavior.Female rats implanted with 28-day osmotic minipumps delivering the SSRI escitalopram throughout pregnancy had serum escitalopram concentrations in a clinically observed range (17-65 ng/ml). A separate cohort of pregnant females exposed to a chronic unpredictable mild stress paradigm on gestational days 10-20 showed elevated baseline (305 ng/ml), and acute stress-induced (463 ng/ml), plasma corticosterone concentrations compared to unstressed controls (109 ng/ml). A final cohort of pregnant dams were exposed to saline (control), escitalopram, stress, or stress and escitalopram to determine the effects on maternal care. Maternal behavior was continuously monitored over the first 10 days after parturition. A reduction of 35 % in maternal contact and 11 % in nursing behavior was observed due to stress during the light cycle. Licking and grooming behavior was unaffected by stress or drug exposure in either the light or dark cycle.These data indicate that: (1) clinically relevant antidepressant treatment during human pregnancy can be modeled in rats using escitalopram; (2) chronic mild stress can be delivered in a manner that does not compromise fetal viability; and (3) neither of these prenatal treatments substantially altered maternal care post parturition.
Published: 2013

17. Escitalopram alters gene expression and HPA axis reactivity in rats following chronic overexpression of corticotropin-releasing factor from the central amygdala

Author: Elizabeth I. Flandreau, Michael J. Owens, Kerry J. Ressler, Chase H. Bourke, Charles B. Nemeroff, and Wylie Vale
Subjects: Male, medicine.medical_specialty, Elevated plus maze, endocrine system, Hypothalamo-Hypophyseal System, Corticotropin-Releasing Hormone, Endocrinology, Diabetes and Metabolism, Serotonin reuptake inhibitor, Hypothalamus, Gene Expression, Pituitary-Adrenal System, Anxiety, Citalopram, Amygdala, Hippocampus, Article, Dexamethasone, Endocrinology, Glucocorticoid receptor, Receptors, Glucocorticoid, Internal medicine, medicine, Escitalopram, Animals, Chronic stress, Biological Psychiatry, Behavior, Animal, Endocrine and Autonomic Systems, Central nucleus of the amygdala, Body Weight, Rats, Psychiatry and Mental health, medicine.anatomical_structure, Antidepressant, Pituitary-Adrenal Function Tests, Psychology, hormones, hormone substitutes, and hormone antagonists, Selective Serotonin Reuptake Inhibitors, medicine.drug
Abstract: We have previously demonstrated that viral-mediated overexpression of corticotropin-releasing factor (CRF) within the central nucleus of the amygdala (CeA) reproduces many of the behavioral and endocrine consequences of chronic stress. The present experiment sought to determine whether administration of the selective serotonin reuptake inhibitor (SSRI) escitalopram reverses the adverse effects of CeA CRF overexpression. In a 2 × 2 design, adult male rats received bilateral infusions of a control lentivirus or a lentivirus in which a portion of the CRF promoter is used to drive increased expression of CRF peptide. Four weeks later, rats were then implanted with an Alzet minipump to deliver vehicle or 10 mg/kg/day escitalopram for a 4-week period of time. The defensive withdrawal (DW) test of anxiety and the sucrose-preference test (SPT) of anhedonia were performed both before and after pump implantation. Additional post-implant behavioral tests included the elevated plus maze (EPM) and social interaction (SI) test. Following completion of behavioral testing, the dexamethasone/CRF test was performed to assess HPA axis reactivity. Brains were collected and expression of HPA axis-relevant transcripts were measured using in situ hybridization. Amygdalar CRF overexpression increased anxiety-like behavior in the DW test at week eight, which was only partially prevented by escitalopram. In both CRF-overexpressing and control groups, escitalopram decreased hippocampal CRF expression while increasing hypothalamic and hippocampal expression of the glucocorticoid receptor (GR). These gene expression changes were associated with a significant decrease in HPA axis reactivity in rats treated with escitalopram. Interestingly, escitalopram increased the rate of weight gain only in rats overexpressing CRF. Overall these data support our hypothesis that amygdalar CRF is critical in anxiety-like behavior; because the antidepressant was unable to reverse behavioral manifestations of CeA CRF-OE. This may be a potential animal model to study treatment-resistant psychopathologies.
Published: 2012

18. Estradiol stimulates an anti-translocation expression pattern of glucocorticoid co-regulators in a hippocampal cell model

Author: Chase H. Bourke, Billie Jeanne Duke, Gretchen N. Neigh, Megan M. Greenlee, Sean D. Kelly, Sanjana A. Malviya, and Douglas C. Eaton
Subjects: medicine.medical_specialty, Hippocampus, Experimental and Cognitive Psychology, Biology, Hippocampal formation, Article, Cell Line, Tacrolimus Binding Proteins, Behavioral Neuroscience, chemistry.chemical_compound, Cyclophilins, Glucocorticoid receptor, Receptors, Glucocorticoid, Corticosterone, Internal medicine, medicine, Animals, Progesterone, Neurons, Estradiol, Rats, Endocrinology, chemistry, Cell culture, FKBP5, Glucocorticoid, medicine.drug, Hormone
Abstract: A consistent clinical finding in patients with major depressive disorder (MDD) is hyperactivity of the hypothalamic–pituitary–adrenal (HPA) axis, the system in the body that facilitates the response to stress. It has been suggested that alterations in glucocorticoid receptor (GR)-mediated feedback prolong activation of the HPA axis, leading to the dysfunction observed in MDD. Additionally, the risk for developing MDD is heightened by several risk factors, namely gender, genetics and early life stress. Previous studies have demonstrated that GR translocation is sexually dimorphic and this difference may be facilitated by differential expression of GR co-regulators. The purpose of this study was to determine the extent to which ovarian hormones alter expression of GR and its co-regulators, Fkbp5 and Ppid, in HT-22 hippocampal neurons. The impact of corticosterone (cort), estradiol (E2), and progesterone (P4) treatments on the expression of the genes Nr3c1, Ppid, and Fkbp5 was assessed in HT-22 hippocampal neurons. Treatment of cells with increasing doses of cort increased the expression of Fkbp5, an effect that was potentiated by E2. Exposure of HT-22 cells to E2 decreased the expression of Ppid and simultaneous exposure to E2 and P4 had combinatory effects on Ppid expression. The effects of E2 on Ppid extend previous work which demonstrated that serum E2 concentrations correlate with hippocampal Ppid expression in female rats. The results presented here illustrate that E2 generates an anti-translocation pattern of GR co-regulators in hippocampal cells.
Published: 2012

19. Stress-induced sex differences: adaptations mediated by the glucocorticoid receptor

Author: Gretchen N. Neigh, Constance S. Harrell, and Chase H. Bourke
Subjects: Male, medicine.medical_specialty, Hypothalamo-Hypophyseal System, Pituitary-Adrenal System, Disease, Biology, medicine.disease_cause, Article, Autoimmunity, Behavioral Neuroscience, Endocrinology, Immune system, Glucocorticoid receptor, Receptors, Glucocorticoid, Internal medicine, medicine, Humans, Chronic stress, Testosterone, Sex Characteristics, Endocrine and Autonomic Systems, Brain, Adaptation, Physiological, Immunology, Female, Glucocorticoid, Stress, Psychological, medicine.drug, Sex characteristics
Abstract: Clinical evidence has indicated that women are more susceptible to stress-related and autoimmune disorders than men. Although females may be more susceptible to some disease states, males do not escape unscathed and are more susceptible to metabolic dysfunction. The hypothalamic-pituitary-axis plays a pivotal role in the sexually dimorphic effects of chronic stress through alterations in negative feedback. Recent evidence has implicated the glucocorticoid receptor and its co-chaperones in the etiology of psychiatric and somatic diseases. Gonadal hormones heavily interact with both glucocorticoid receptor expression and glucocorticoid receptor action either through direct or indirect effects on proteins in the chaperone and co-chaperone complex. Diverse systems including the hypothalamic-pituitary-axis, the immune system, and metabolism are affected differently in males and females, possibly through the glucocorticoid receptor system. New considerations of glucocorticoid regulation through the co-chaperone complex in the brain will be vital to the development of treatment strategies for men and women afflicted by neuropsychiatric and somatic disorders.
Published: 2011

20. Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner

Author: Cory A. Bradburn, Gretchen N. Neigh, Chase H. Bourke, Elisabeth B. Binder, Madiha Q. Raees, and Sanjana A. Malviya
Subjects: Dominance-Subordination, Male, Restraint, Physical, medicine.medical_specialty, Hypothalamo-Hypophyseal System, Endocrinology, Diabetes and Metabolism, Pituitary-Adrenal System, Biology, Hippocampus, Article, Social defeat, Tacrolimus Binding Proteins, chemistry.chemical_compound, Cyclophilins, Endocrinology, Glucocorticoid receptor, Receptors, Glucocorticoid, Corticosterone, Internal medicine, medicine, Animals, Chronic stress, Sexual Maturation, Rats, Wistar, Gonadal Steroid Hormones, Biological Psychiatry, Sex Characteristics, Endocrine and Autonomic Systems, Gene Expression Regulation, Developmental, Rats, Up-Regulation, Sexual dimorphism, DNA-Binding Proteins, Psychiatry and Mental health, Phenotype, chemistry, Chronic Disease, Female, FKBP5, Glucocorticoid, Stress, Psychological, Sex characteristics, medicine.drug, Transcription Factors
Abstract: Early life stress precipitates dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and this effect is most pronounced in females. The mechanisms that mediate female sensitivity to stress-induced HPA axis dysregulation are unknown. The purpose of this study was to determine whether sex moderates the effects of chronic adolescent stress on glucocorticoid receptor (GR) translocation and moderators of the GR system. Female adolescent rats with a history of chronic stress exposure demonstrated a delayed resolution of the plasma corticosterone response to an acute stressor and this delay was accompanied by attenuated GR translocation compared to control adolescent females. The chronic stress-induced phenotype in females was similar to the baseline phenotype in male adolescent rats. Conversely, the expression patterns of GR moderators/co-chaperones became more sexually dimorphic following chronic stress, suggesting divergent function of the GR system between male and female adolescent rats. Gene expression of Ppid, a positive regulator of the GR, was predicted by plasma estradiol and 34% lower in control adolescent females than males, indicating that sex steroids may play a role in the sexually dimorphic response. After chronic adolescent stress, females displayed elevated hippocampal expression of Bag1 and Ppid genes that was not observed in males. Overall, the GR output to an acute stressor, illustrated by transcription of Nr3c1 (encoding the GR), Bag1, Fkbp5, Ppid, and Src1, was significantly upregulated and differed in a sex-specific and chronic stress-dependent manner. This study provides new evidence for sex differences during development and adaptation of the glucocorticoid receptor chaperone system.
Published: 2011

21. Adverse Effect

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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22. Adolescent Neurodevelopmental Vulnerability

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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23. Single Barrel Micropipette

Author: Michael M. Morgan, MacDonald J. Christie, Luis De Lecea, Jason C. G. Halford, Josee E. Leysen, Warren H. Meck, Catalin V. Buhusi, Marcy J. Bubar, Kathryn A. Cunningham, Richard W. Foltin, David C. S. Roberts, Andreas Marneros, Alex Hofer, Bart Ellenbroek, Christoph U. Correll, Paul Newhouse, Heather Wilkins, Joris C. Verster, Emma Childs, Gary Remington, Edoardo Spina, W. Wolfgang Fleischhacker, John Atack, Hilde Lavreysen, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Dan J. Stein, Anthony L. Riley, Steve Kohut, Angela Roberts, Marilyn E. Carroll, Peter A. Santi, Stefan Leucht, Klaus A. Miczek, Eileen M. Joyce, Jonathan P. Roiser, Celia J. A. Morgan, Valerie H. Curran, Mary E. Cain, Michael T. Bardo, Terry E. Robinson, Ian Hindmarch, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Sidney H. Kennedy, Sakina J. Rizvi, Thomas Steckler, Seiya Miyamoto, Sakire Pogun, Gorkem Yararbas, Jill B. Becker, Anders Ågmo, Vera Astreika, Robert Segraves, Rodrigo Andrade, Yogita Chudasama, Roshan Cools, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Bernard Le Foll, Trevor W. Robbins, Husseini K. Manji, Jorge A. Quiroz, Jos Prickaerts, Ennio Esposito, William Invernizzi, Sophie Tambour, John C. Crabbe, Peter J. Flor, Inga D. Neumann, Malcolm Lader, Joseph Zohar, Seithikurippu R. Pandi-Perumal, Milton Kramer, Michael J. Thorpy, Shelby Freedman Harris, D. Warren Spence, Gabriele Fischer, Annemarie Unger, Samuel B. Hutton, Huaiyu Yang, George I. Papakostas, S. Kasper, Frank Sams-Dodd, Yavin Shaham, John R. Mantsch, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul D. Callaghan, Iain S. McGregor, Murray R. Thompson, Michel Billiard, Brian A. Fallon, Kelli J. Harding, Daniel Hoyer, Jacques Epelbaum, Cécile Viollet, Mischa de Rover, Sander Nieuwenhuis, Stan Floresco, Anne Jackson, Mitul A. Mehta, Johannes Mosbacher, Ronald L. Cowan, Robert Kessler, Peter H. Boeijinga, James Winslow, A. Claudio Cuello, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Ashwini Padhi, Naomi A. Fineberg, Mark A. Geyer, Francis C. Colpaert, Andrew Young, Ronald F. Mucha, Christof Baltes, Thomas Mueggler, Markus Rudin, Giovanni Hernandez, Peter Shizgal, Marc N. Branch, Ian P. Stolerman, Sharon Morein-Zamir, Barbara J. Sahakian, Sunila G. Nair, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, R. H. De Rijk, E. R. de Kloet, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Maria Isabel Colado, A. Richard Green, Suzanne H. Mitchell, Harriet de Wit, Alyson J. Bond, Christine A. Franco, Marc N. Potenza, Caroline Cohen, Marc Turiault, Guy Griebel, Darren R. Christensen, Warren K. Bickel, Michael J. Owens, Chase H. Bourke, Gustavo Turecki, Britta Hahn, Sarah Morgan, Angus Mackay, Matthew I. Palmatier, Rick A. Bevins, Lawrence Scahill, Andrea Bari, Stephen B. Dunnett, Karim Nader, Oliver Hardt, Paola V. Migues, R. Andrew Chambers, and David E. Nichols
Published: 2010
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24. Allosteric Site

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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25. Strattera™

Author: Michael M. Morgan, MacDonald J. Christie, Luis De Lecea, Jason C. G. Halford, Josee E. Leysen, Warren H. Meck, Catalin V. Buhusi, Marcy J. Bubar, Kathryn A. Cunningham, Richard W. Foltin, David C. S. Roberts, Andreas Marneros, Alex Hofer, Bart Ellenbroek, Christoph U. Correll, Paul Newhouse, Heather Wilkins, Joris C. Verster, Emma Childs, Gary Remington, Edoardo Spina, W. Wolfgang Fleischhacker, John Atack, Hilde Lavreysen, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Dan J. Stein, Anthony L. Riley, Steve Kohut, Angela Roberts, Marilyn E. Carroll, Peter A. Santi, Stefan Leucht, Klaus A. Miczek, Eileen M. Joyce, Jonathan P. Roiser, Celia J. A. Morgan, Valerie H. Curran, Mary E. Cain, Michael T. Bardo, Terry E. Robinson, Ian Hindmarch, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Sidney H. Kennedy, Sakina J. Rizvi, Thomas Steckler, Seiya Miyamoto, Sakire Pogun, Gorkem Yararbas, Jill B. Becker, Anders Ågmo, Vera Astreika, Robert Segraves, Rodrigo Andrade, Yogita Chudasama, Roshan Cools, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Bernard Le Foll, Trevor W. Robbins, Husseini K. Manji, Jorge A. Quiroz, Jos Prickaerts, Ennio Esposito, William Invernizzi, Sophie Tambour, John C. Crabbe, Peter J. Flor, Inga D. Neumann, Malcolm Lader, Joseph Zohar, Seithikurippu R. Pandi-Perumal, Milton Kramer, Michael J. Thorpy, Shelby Freedman Harris, D. Warren Spence, Gabriele Fischer, Annemarie Unger, Samuel B. Hutton, Huaiyu Yang, George I. Papakostas, S. Kasper, Frank Sams-Dodd, Yavin Shaham, John R. Mantsch, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul D. Callaghan, Iain S. McGregor, Murray R. Thompson, Michel Billiard, Brian A. Fallon, Kelli J. Harding, Daniel Hoyer, Jacques Epelbaum, Cécile Viollet, Mischa de Rover, Sander Nieuwenhuis, Stan Floresco, Anne Jackson, Mitul A. Mehta, Johannes Mosbacher, Ronald L. Cowan, Robert Kessler, Peter H. Boeijinga, James Winslow, A. Claudio Cuello, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Ashwini Padhi, Naomi A. Fineberg, Mark A. Geyer, Francis C. Colpaert, Andrew Young, Ronald F. Mucha, Christof Baltes, Thomas Mueggler, Markus Rudin, Giovanni Hernandez, Peter Shizgal, Marc N. Branch, Ian P. Stolerman, Sharon Morein-Zamir, Barbara J. Sahakian, Sunila G. Nair, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, R. H. De Rijk, E. R. de Kloet, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Maria Isabel Colado, A. Richard Green, Suzanne H. Mitchell, Harriet de Wit, Alyson J. Bond, Christine A. Franco, Marc N. Potenza, Caroline Cohen, Marc Turiault, Guy Griebel, Darren R. Christensen, Warren K. Bickel, Michael J. Owens, Chase H. Bourke, Gustavo Turecki, Britta Hahn, Sarah Morgan, Angus Mackay, Matthew I. Palmatier, Rick A. Bevins, Lawrence Scahill, Andrea Bari, Stephen B. Dunnett, Karim Nader, Oliver Hardt, Paola V. Migues, R. Andrew Chambers, and David E. Nichols
Published: 2010
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26. Selective Attention

Author: Michael M. Morgan, MacDonald J. Christie, Luis De Lecea, Jason C. G. Halford, Josee E. Leysen, Warren H. Meck, Catalin V. Buhusi, Marcy J. Bubar, Kathryn A. Cunningham, Richard W. Foltin, David C. S. Roberts, Andreas Marneros, Alex Hofer, Bart Ellenbroek, Christoph U. Correll, Paul Newhouse, Heather Wilkins, Joris C. Verster, Emma Childs, Gary Remington, Edoardo Spina, W. Wolfgang Fleischhacker, John Atack, Hilde Lavreysen, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Dan J. Stein, Anthony L. Riley, Steve Kohut, Angela Roberts, Marilyn E. Carroll, Peter A. Santi, Stefan Leucht, Klaus A. Miczek, Eileen M. Joyce, Jonathan P. Roiser, Celia J. A. Morgan, Valerie H. Curran, Mary E. Cain, Michael T. Bardo, Terry E. Robinson, Ian Hindmarch, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Sidney H. Kennedy, Sakina J. Rizvi, Thomas Steckler, Seiya Miyamoto, Sakire Pogun, Gorkem Yararbas, Jill B. Becker, Anders Ågmo, Vera Astreika, Robert Segraves, Rodrigo Andrade, Yogita Chudasama, Roshan Cools, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Bernard Le Foll, Trevor W. Robbins, Husseini K. Manji, Jorge A. Quiroz, Jos Prickaerts, Ennio Esposito, William Invernizzi, Sophie Tambour, John C. Crabbe, Peter J. Flor, Inga D. Neumann, Malcolm Lader, Joseph Zohar, Seithikurippu R. Pandi-Perumal, Milton Kramer, Michael J. Thorpy, Shelby Freedman Harris, D. Warren Spence, Gabriele Fischer, Annemarie Unger, Samuel B. Hutton, Huaiyu Yang, George I. Papakostas, S. Kasper, Frank Sams-Dodd, Yavin Shaham, John R. Mantsch, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul D. Callaghan, Iain S. McGregor, Murray R. Thompson, Michel Billiard, Brian A. Fallon, Kelli J. Harding, Daniel Hoyer, Jacques Epelbaum, Cécile Viollet, Mischa de Rover, Sander Nieuwenhuis, Stan Floresco, Anne Jackson, Mitul A. Mehta, Johannes Mosbacher, Ronald L. Cowan, Robert Kessler, Peter H. Boeijinga, James Winslow, A. Claudio Cuello, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Ashwini Padhi, Naomi A. Fineberg, Mark A. Geyer, Francis C. Colpaert, Andrew Young, Ronald F. Mucha, Christof Baltes, Thomas Mueggler, Markus Rudin, Giovanni Hernandez, Peter Shizgal, Marc N. Branch, Ian P. Stolerman, Sharon Morein-Zamir, Barbara J. Sahakian, Sunila G. Nair, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, R. H. De Rijk, E. R. de Kloet, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Maria Isabel Colado, A. Richard Green, Suzanne H. Mitchell, Harriet de Wit, Alyson J. Bond, Christine A. Franco, Marc N. Potenza, Caroline Cohen, Marc Turiault, Guy Griebel, Darren R. Christensen, Warren K. Bickel, Michael J. Owens, Chase H. Bourke, Gustavo Turecki, Britta Hahn, Sarah Morgan, Angus Mackay, Matthew I. Palmatier, Rick A. Bevins, Lawrence Scahill, Andrea Bari, Stephen B. Dunnett, Karim Nader, Oliver Hardt, Paola V. Migues, R. Andrew Chambers, and David E. Nichols
Published: 2010
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27. Selective Noradrenergic Reuptake Inhibitors

Author: Michael M. Morgan, MacDonald J. Christie, Luis De Lecea, Jason C. G. Halford, Josee E. Leysen, Warren H. Meck, Catalin V. Buhusi, Marcy J. Bubar, Kathryn A. Cunningham, Richard W. Foltin, David C. S. Roberts, Andreas Marneros, Alex Hofer, Bart Ellenbroek, Christoph U. Correll, Paul Newhouse, Heather Wilkins, Joris C. Verster, Emma Childs, Gary Remington, Edoardo Spina, W. Wolfgang Fleischhacker, John Atack, Hilde Lavreysen, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Dan J. Stein, Anthony L. Riley, Steve Kohut, Angela Roberts, Marilyn E. Carroll, Peter A. Santi, Stefan Leucht, Klaus A. Miczek, Eileen M. Joyce, Jonathan P. Roiser, Celia J. A. Morgan, Valerie H. Curran, Mary E. Cain, Michael T. Bardo, Terry E. Robinson, Ian Hindmarch, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Sidney H. Kennedy, Sakina J. Rizvi, Thomas Steckler, Seiya Miyamoto, Sakire Pogun, Gorkem Yararbas, Jill B. Becker, Anders Ågmo, Vera Astreika, Robert Segraves, Rodrigo Andrade, Yogita Chudasama, Roshan Cools, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Bernard Le Foll, Trevor W. Robbins, Husseini K. Manji, Jorge A. Quiroz, Jos Prickaerts, Ennio Esposito, William Invernizzi, Sophie Tambour, John C. Crabbe, Peter J. Flor, Inga D. Neumann, Malcolm Lader, Joseph Zohar, Seithikurippu R. Pandi-Perumal, Milton Kramer, Michael J. Thorpy, Shelby Freedman Harris, D. Warren Spence, Gabriele Fischer, Annemarie Unger, Samuel B. Hutton, Huaiyu Yang, George I. Papakostas, S. Kasper, Frank Sams-Dodd, Yavin Shaham, John R. Mantsch, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul D. Callaghan, Iain S. McGregor, Murray R. Thompson, Michel Billiard, Brian A. Fallon, Kelli J. Harding, Daniel Hoyer, Jacques Epelbaum, Cécile Viollet, Mischa de Rover, Sander Nieuwenhuis, Stan Floresco, Anne Jackson, Mitul A. Mehta, Johannes Mosbacher, Ronald L. Cowan, Robert Kessler, Peter H. Boeijinga, James Winslow, A. Claudio Cuello, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Ashwini Padhi, Naomi A. Fineberg, Mark A. Geyer, Francis C. Colpaert, Andrew Young, Ronald F. Mucha, Christof Baltes, Thomas Mueggler, Markus Rudin, Giovanni Hernandez, Peter Shizgal, Marc N. Branch, Ian P. Stolerman, Sharon Morein-Zamir, Barbara J. Sahakian, Sunila G. Nair, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, R. H. De Rijk, E. R. de Kloet, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Maria Isabel Colado, A. Richard Green, Suzanne H. Mitchell, Harriet de Wit, Alyson J. Bond, Christine A. Franco, Marc N. Potenza, Caroline Cohen, Marc Turiault, Guy Griebel, Darren R. Christensen, Warren K. Bickel, Michael J. Owens, Chase H. Bourke, Gustavo Turecki, Britta Hahn, Sarah Morgan, Angus Mackay, Matthew I. Palmatier, Rick A. Bevins, Lawrence Scahill, Andrea Bari, Stephen B. Dunnett, Karim Nader, Oliver Hardt, Paola V. Migues, R. Andrew Chambers, and David E. Nichols
Published: 2010
Full Text: View/download PDF

28. Action Inhibition

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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29. Avoidance

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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30. Childhood Disintegrative Disorder

Author: Daniel Hoyer, Eric P Zorrilla, Pietro Cottone, Sarah Parylak, Micaela Morelli, Nicola Simola, James D. Lane, Michael M Morgan, M J Christie, Cecilia J. Hillard, Alan J. Budney, Ryan G. Vandrey, Trevor Robbins, Paolo Nencini, Michele Stanislaw Milella, Naheed (Max) Mirza, Victoria L Harvey, Tony Dickenson, Seiya Miyamoto, Osborne Almeida, Nuno Sousa, S Yu, Anthony Absalom, David Menon, Pedro L. Delgado, Cyril Höschl, Tara L White, Richard Depue, Christof Baltes, Thomas Mueggler, Markus Rudin, Peter J Flor, Inga Neumann, Craig A Erickson, David J Posey, Kelly Blankenship, Kimberly A Stigler, Christopher J. McDougle, Etienne Sibille, Nicole Edgar, Malcolm Lader, Theodora Duka, Emma Childs, Britta Hahn, Jaanus Harro, Paul Newhouse, Heather Wilkins, Yesne Alici, William Breitbart, Eric Nestler, Anthony R Isles, Lawrence Wilkinson, Subhash Pandey, Samuel G. Siris, Paul Willner, Michel Billiard, Björn Lemmer, Jean-Michel Scherrmann, Lawrence H. Price, Tomek J Banasikowski, Richard J Beninger, John Harvey, Brian E. Leonard, Kim Wolff, Ashwini Padhi, Naomi Fineberg, Warren H Meck, Catalin V Buhushi, Lance Richard McMahon, Yogita Chudasama, Michael Kuhar, Joachim D. Uys, Peter W. Kalivas, Mohammed Shoaib, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Michael Bloch, James F Leckman, Barbara J. Sahakian, Sharon Morein-Zamir, Anne Jackson, Ben J Harrison, Christos Pantelis, Ian Hindmarch, Alyson J Bond, Jaime M Monti, Darren R Christensen, Warren K. Bickel, Marcy J Bubar, Kathryn A Cunningham, Christine A Franco, Marc Potenza, Maria-Inés López-Ibor, Juan J López-Ibor, Joseph H Friedman, Alex Hofer, Tomek J. Banasikowski, Richard J. Beninger, Matthew I Palmatier, Rick A Bevins, Thomas Tzschentke, David Roberts, Stephan Anagnostaras, Jennifer R Sage, Stephanie A Carmack, Stephen J. Kohut, Anthony L. Riley, Ronald F. Mucha, Jos Prickaerts, Oliver Stiedl, Sven Ove Ögren, Karim Nader, Oliver Hardt, Paola V. Migues, Arthur Christopoulos, Gregory D Stewart, Patrick M Sexton, Yavin Shaham, Sunila G Nair, Sarah H Heil, Stacey C Sigmon, Stephen T. Higgins, Sarah H. Heil, Stacey C. Sigmon, Marc N Branch, Mary Cain, Michael T Bardo, Robert L Balster, Sharon Walsh, Roel de Rijk, Ronald De Kloet, Chase H. Bourke, Michael J. Owens, Cécile Viollet, Jacques Epelbaum, Karl Mann, Falk Kiefer, Michael Owens, Chase Bourke, Hamish McAllister-Williams, Andreas Marneros, Rodrigo Andrade, Ivan Izquierdo, Lia Rejane M Bevilaqua, Martin Cammarota, Christoph Hiemke, Maria Isabel Colado, and Richard Green
Published: 2010
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31. Imaging Mass Spectrometry

Author: Marilyn E. Carroll, Peter A. Santi, Joseph Zohar, Thomas R. E. Barnes, Peter Verheart, Per Svenningsson, Per E. Andrén, Lawrence H. Price, Johannes Wancata, Kim Fromme, Amee B. Patel, Anthony R. Isles, Lawrence S. Wilkinson, Jon E. Grant, Brian L. Odlaug, Rosa M. M. de Almeida, Klaus A. Miczek, Suzanne H. Mitchell, de Harriet Wit, Alyson J. Bond, Anthony L. Riley, Steve Kohut, Alex Hofer, Darren R. Christensen, Warren K. Bickel, Harriet de Wit, Stephen C. Fowler, Pedro L. Delgado, Etienne Sibille, Nicole Edgar, Maria-Inés López-Ibor, Juan J. López-Ibor, Robert L. Balster, Celia J. A. Morgan, Valerie H. Curran, Hans Möhler, Malcolm Lader, Anthony Dickinson, Peter Riederer, Siegfried Hoyer, Josee E. Leysen, Jos Prickaerts, Michael M. Morgan, MacDonald J. Christie, Warren H. Meck, Catalin V. Buhushi, Rodrigo Andrade, Peter Shizgal, Giovanni Hernandez, David S. Tait, Verity J. Brown, Gail Winger, Mei-Chuan Ko, James H. Woods, Peter J. Tyrer, Gregory D. Stewart, Patrick M. Sexton, Arthur Christopoulos, Mischa De Rover, Sander Nieuwenhuis, Trevor W. Robbins, Mark Slifstein, Michael J. Owens, Chase H. Bourke, Bart Ellenbroek, and Bankole A. Johnson
Published: 2010
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32. Allosteric Modulators

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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33. Concept Formation Test

Author: Daniel Hoyer, Eric P Zorrilla, Pietro Cottone, Sarah Parylak, Micaela Morelli, Nicola Simola, James D. Lane, Michael M Morgan, M J Christie, Cecilia J. Hillard, Alan J. Budney, Ryan G. Vandrey, Trevor Robbins, Paolo Nencini, Michele Stanislaw Milella, Naheed (Max) Mirza, Victoria L Harvey, Tony Dickenson, Seiya Miyamoto, Osborne Almeida, Nuno Sousa, S Yu, Anthony Absalom, David Menon, Pedro L. Delgado, Cyril Höschl, Tara L White, Richard Depue, Christof Baltes, Thomas Mueggler, Markus Rudin, Peter J Flor, Inga Neumann, Craig A Erickson, David J Posey, Kelly Blankenship, Kimberly A Stigler, Christopher J. McDougle, Etienne Sibille, Nicole Edgar, Malcolm Lader, Theodora Duka, Emma Childs, Britta Hahn, Jaanus Harro, Paul Newhouse, Heather Wilkins, Yesne Alici, William Breitbart, Eric Nestler, Anthony R Isles, Lawrence Wilkinson, Subhash Pandey, Samuel G. Siris, Paul Willner, Michel Billiard, Björn Lemmer, Jean-Michel Scherrmann, Lawrence H. Price, Tomek J Banasikowski, Richard J Beninger, John Harvey, Brian E. Leonard, Kim Wolff, Ashwini Padhi, Naomi Fineberg, Warren H Meck, Catalin V Buhushi, Lance Richard McMahon, Yogita Chudasama, Michael Kuhar, Joachim D. Uys, Peter W. Kalivas, Mohammed Shoaib, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Michael Bloch, James F Leckman, Barbara J. Sahakian, Sharon Morein-Zamir, Anne Jackson, Ben J Harrison, Christos Pantelis, Ian Hindmarch, Alyson J Bond, Jaime M Monti, Darren R Christensen, Warren K. Bickel, Marcy J Bubar, Kathryn A Cunningham, Christine A Franco, Marc Potenza, Maria-Inés López-Ibor, Juan J López-Ibor, Joseph H Friedman, Alex Hofer, Tomek J. Banasikowski, Richard J. Beninger, Matthew I Palmatier, Rick A Bevins, Thomas Tzschentke, David Roberts, Stephan Anagnostaras, Jennifer R Sage, Stephanie A Carmack, Stephen J. Kohut, Anthony L. Riley, Ronald F. Mucha, Jos Prickaerts, Oliver Stiedl, Sven Ove Ögren, Karim Nader, Oliver Hardt, Paola V. Migues, Arthur Christopoulos, Gregory D Stewart, Patrick M Sexton, Yavin Shaham, Sunila G Nair, Sarah H Heil, Stacey C Sigmon, Stephen T. Higgins, Sarah H. Heil, Stacey C. Sigmon, Marc N Branch, Mary Cain, Michael T Bardo, Robert L Balster, Sharon Walsh, Roel de Rijk, Ronald De Kloet, Chase H. Bourke, Michael J. Owens, Cécile Viollet, Jacques Epelbaum, Karl Mann, Falk Kiefer, Michael Owens, Chase Bourke, Hamish McAllister-Williams, Andreas Marneros, Rodrigo Andrade, Ivan Izquierdo, Lia Rejane M Bevilaqua, Martin Cammarota, Christoph Hiemke, Maria Isabel Colado, and Richard Green
Published: 2010
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34. Acetaldehyde

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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35. Constitutional

Author: Daniel Hoyer, Eric P Zorrilla, Pietro Cottone, Sarah Parylak, Micaela Morelli, Nicola Simola, James D. Lane, Michael M Morgan, M J Christie, Cecilia J. Hillard, Alan J. Budney, Ryan G. Vandrey, Trevor Robbins, Paolo Nencini, Michele Stanislaw Milella, Naheed (Max) Mirza, Victoria L Harvey, Tony Dickenson, Seiya Miyamoto, Osborne Almeida, Nuno Sousa, S Yu, Anthony Absalom, David Menon, Pedro L. Delgado, Cyril Höschl, Tara L White, Richard Depue, Christof Baltes, Thomas Mueggler, Markus Rudin, Peter J Flor, Inga Neumann, Craig A Erickson, David J Posey, Kelly Blankenship, Kimberly A Stigler, Christopher J. McDougle, Etienne Sibille, Nicole Edgar, Malcolm Lader, Theodora Duka, Emma Childs, Britta Hahn, Jaanus Harro, Paul Newhouse, Heather Wilkins, Yesne Alici, William Breitbart, Eric Nestler, Anthony R Isles, Lawrence Wilkinson, Subhash Pandey, Samuel G. Siris, Paul Willner, Michel Billiard, Björn Lemmer, Jean-Michel Scherrmann, Lawrence H. Price, Tomek J Banasikowski, Richard J Beninger, John Harvey, Brian E. Leonard, Kim Wolff, Ashwini Padhi, Naomi Fineberg, Warren H Meck, Catalin V Buhushi, Lance Richard McMahon, Yogita Chudasama, Michael Kuhar, Joachim D. Uys, Peter W. Kalivas, Mohammed Shoaib, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Michael Bloch, James F Leckman, Barbara J. Sahakian, Sharon Morein-Zamir, Anne Jackson, Ben J Harrison, Christos Pantelis, Ian Hindmarch, Alyson J Bond, Jaime M Monti, Darren R Christensen, Warren K. Bickel, Marcy J Bubar, Kathryn A Cunningham, Christine A Franco, Marc Potenza, Maria-Inés López-Ibor, Juan J López-Ibor, Joseph H Friedman, Alex Hofer, Tomek J. Banasikowski, Richard J. Beninger, Matthew I Palmatier, Rick A Bevins, Thomas Tzschentke, David Roberts, Stephan Anagnostaras, Jennifer R Sage, Stephanie A Carmack, Stephen J. Kohut, Anthony L. Riley, Ronald F. Mucha, Jos Prickaerts, Oliver Stiedl, Sven Ove Ögren, Karim Nader, Oliver Hardt, Paola V. Migues, Arthur Christopoulos, Gregory D Stewart, Patrick M Sexton, Yavin Shaham, Sunila G Nair, Sarah H Heil, Stacey C Sigmon, Stephen T. Higgins, Sarah H. Heil, Stacey C. Sigmon, Marc N Branch, Mary Cain, Michael T Bardo, Robert L Balster, Sharon Walsh, Roel de Rijk, Ronald De Kloet, Chase H. Bourke, Michael J. Owens, Cécile Viollet, Jacques Epelbaum, Karl Mann, Falk Kiefer, Michael Owens, Chase Bourke, Hamish McAllister-Williams, Andreas Marneros, Rodrigo Andrade, Ivan Izquierdo, Lia Rejane M Bevilaqua, Martin Cammarota, Christoph Hiemke, Maria Isabel Colado, and Richard Green
Published: 2010
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36. Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study

Author: Daniel Hoyer, Eric P Zorrilla, Pietro Cottone, Sarah Parylak, Micaela Morelli, Nicola Simola, James D. Lane, Michael M Morgan, M J Christie, Cecilia J. Hillard, Alan J. Budney, Ryan G. Vandrey, Trevor Robbins, Paolo Nencini, Michele Stanislaw Milella, Naheed (Max) Mirza, Victoria L Harvey, Tony Dickenson, Seiya Miyamoto, Osborne Almeida, Nuno Sousa, S Yu, Anthony Absalom, David Menon, Pedro L. Delgado, Cyril Höschl, Tara L White, Richard Depue, Christof Baltes, Thomas Mueggler, Markus Rudin, Peter J Flor, Inga Neumann, Craig A Erickson, David J Posey, Kelly Blankenship, Kimberly A Stigler, Christopher J. McDougle, Etienne Sibille, Nicole Edgar, Malcolm Lader, Theodora Duka, Emma Childs, Britta Hahn, Jaanus Harro, Paul Newhouse, Heather Wilkins, Yesne Alici, William Breitbart, Eric Nestler, Anthony R Isles, Lawrence Wilkinson, Subhash Pandey, Samuel G. Siris, Paul Willner, Michel Billiard, Björn Lemmer, Jean-Michel Scherrmann, Lawrence H. Price, Tomek J Banasikowski, Richard J Beninger, John Harvey, Brian E. Leonard, Kim Wolff, Ashwini Padhi, Naomi Fineberg, Warren H Meck, Catalin V Buhushi, Lance Richard McMahon, Yogita Chudasama, Michael Kuhar, Joachim D. Uys, Peter W. Kalivas, Mohammed Shoaib, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Michael Bloch, James F Leckman, Barbara J. Sahakian, Sharon Morein-Zamir, Anne Jackson, Ben J Harrison, Christos Pantelis, Ian Hindmarch, Alyson J Bond, Jaime M Monti, Darren R Christensen, Warren K. Bickel, Marcy J Bubar, Kathryn A Cunningham, Christine A Franco, Marc Potenza, Maria-Inés López-Ibor, Juan J López-Ibor, Joseph H Friedman, Alex Hofer, Tomek J. Banasikowski, Richard J. Beninger, Matthew I Palmatier, Rick A Bevins, Thomas Tzschentke, David Roberts, Stephan Anagnostaras, Jennifer R Sage, Stephanie A Carmack, Stephen J. Kohut, Anthony L. Riley, Ronald F. Mucha, Jos Prickaerts, Oliver Stiedl, Sven Ove Ögren, Karim Nader, Oliver Hardt, Paola V. Migues, Arthur Christopoulos, Gregory D Stewart, Patrick M Sexton, Yavin Shaham, Sunila G Nair, Sarah H Heil, Stacey C Sigmon, Stephen T. Higgins, Sarah H. Heil, Stacey C. Sigmon, Marc N Branch, Mary Cain, Michael T Bardo, Robert L Balster, Sharon Walsh, Roel de Rijk, Ronald De Kloet, Chase H. Bourke, Michael J. Owens, Cécile Viollet, Jacques Epelbaum, Karl Mann, Falk Kiefer, Michael Owens, Chase Bourke, Hamish McAllister-Williams, Andreas Marneros, Rodrigo Andrade, Ivan Izquierdo, Lia Rejane M Bevilaqua, Martin Cammarota, Christoph Hiemke, Maria Isabel Colado, and Richard Green
Published: 2010
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37. Inhibitory Amino Acids and Their Receptor Ligands

Author: Marilyn E. Carroll, Peter A. Santi, Joseph Zohar, Thomas R. E. Barnes, Peter Verheart, Per Svenningsson, Per E. Andrén, Lawrence H. Price, Johannes Wancata, Kim Fromme, Amee B. Patel, Anthony R. Isles, Lawrence S. Wilkinson, Jon E. Grant, Brian L. Odlaug, Rosa M. M. de Almeida, Klaus A. Miczek, Suzanne H. Mitchell, de Harriet Wit, Alyson J. Bond, Anthony L. Riley, Steve Kohut, Alex Hofer, Darren R. Christensen, Warren K. Bickel, Harriet de Wit, Stephen C. Fowler, Pedro L. Delgado, Etienne Sibille, Nicole Edgar, Maria-Inés López-Ibor, Juan J. López-Ibor, Robert L. Balster, Celia J. A. Morgan, Valerie H. Curran, Hans Möhler, Malcolm Lader, Anthony Dickinson, Peter Riederer, Siegfried Hoyer, Josee E. Leysen, Jos Prickaerts, Michael M. Morgan, MacDonald J. Christie, Warren H. Meck, Catalin V. Buhushi, Rodrigo Andrade, Peter Shizgal, Giovanni Hernandez, David S. Tait, Verity J. Brown, Gail Winger, Mei-Chuan Ko, James H. Woods, Peter J. Tyrer, Gregory D. Stewart, Patrick M. Sexton, Arthur Christopoulos, Mischa De Rover, Sander Nieuwenhuis, Trevor W. Robbins, Mark Slifstein, Michael J. Owens, Chase H. Bourke, Bart Ellenbroek, and Bankole A. Johnson
Published: 2010
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38. Antidepressants: Recent Developments

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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39. Second and Third Generation Antipsychotics

Author: Michael M. Morgan, MacDonald J. Christie, Luis De Lecea, Jason C. G. Halford, Josee E. Leysen, Warren H. Meck, Catalin V. Buhusi, Marcy J. Bubar, Kathryn A. Cunningham, Richard W. Foltin, David C. S. Roberts, Andreas Marneros, Alex Hofer, Bart Ellenbroek, Christoph U. Correll, Paul Newhouse, Heather Wilkins, Joris C. Verster, Emma Childs, Gary Remington, Edoardo Spina, W. Wolfgang Fleischhacker, John Atack, Hilde Lavreysen, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Dan J. Stein, Anthony L. Riley, Steve Kohut, Angela Roberts, Marilyn E. Carroll, Peter A. Santi, Stefan Leucht, Klaus A. Miczek, Eileen M. Joyce, Jonathan P. Roiser, Celia J. A. Morgan, Valerie H. Curran, Mary E. Cain, Michael T. Bardo, Terry E. Robinson, Ian Hindmarch, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Sidney H. Kennedy, Sakina J. Rizvi, Thomas Steckler, Seiya Miyamoto, Sakire Pogun, Gorkem Yararbas, Jill B. Becker, Anders Ågmo, Vera Astreika, Robert Segraves, Rodrigo Andrade, Yogita Chudasama, Roshan Cools, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Bernard Le Foll, Trevor W. Robbins, Husseini K. Manji, Jorge A. Quiroz, Jos Prickaerts, Ennio Esposito, William Invernizzi, Sophie Tambour, John C. Crabbe, Peter J. Flor, Inga D. Neumann, Malcolm Lader, Joseph Zohar, Seithikurippu R. Pandi-Perumal, Milton Kramer, Michael J. Thorpy, Shelby Freedman Harris, D. Warren Spence, Gabriele Fischer, Annemarie Unger, Samuel B. Hutton, Huaiyu Yang, George I. Papakostas, S. Kasper, Frank Sams-Dodd, Yavin Shaham, John R. Mantsch, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul D. Callaghan, Iain S. McGregor, Murray R. Thompson, Michel Billiard, Brian A. Fallon, Kelli J. Harding, Daniel Hoyer, Jacques Epelbaum, Cécile Viollet, Mischa de Rover, Sander Nieuwenhuis, Stan Floresco, Anne Jackson, Mitul A. Mehta, Johannes Mosbacher, Ronald L. Cowan, Robert Kessler, Peter H. Boeijinga, James Winslow, A. Claudio Cuello, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Ashwini Padhi, Naomi A. Fineberg, Mark A. Geyer, Francis C. Colpaert, Andrew Young, Ronald F. Mucha, Christof Baltes, Thomas Mueggler, Markus Rudin, Giovanni Hernandez, Peter Shizgal, Marc N. Branch, Ian P. Stolerman, Sharon Morein-Zamir, Barbara J. Sahakian, Sunila G. Nair, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, R. H. De Rijk, E. R. de Kloet, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Maria Isabel Colado, A. Richard Green, Suzanne H. Mitchell, Harriet de Wit, Alyson J. Bond, Christine A. Franco, Marc N. Potenza, Caroline Cohen, Marc Turiault, Guy Griebel, Darren R. Christensen, Warren K. Bickel, Michael J. Owens, Chase H. Bourke, Gustavo Turecki, Britta Hahn, Sarah Morgan, Angus Mackay, Matthew I. Palmatier, Rick A. Bevins, Lawrence Scahill, Andrea Bari, Stephen B. Dunnett, Karim Nader, Oliver Hardt, Paola V. Migues, R. Andrew Chambers, and David E. Nichols
Published: 2010
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40. Atypical Antipsychotic Drugs

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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41. Atypical Autism

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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42. Area Under the Curve

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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43. Amentia

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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44. Continuous Reinforcement

Author: Daniel Hoyer, Eric P Zorrilla, Pietro Cottone, Sarah Parylak, Micaela Morelli, Nicola Simola, James D. Lane, Michael M Morgan, M J Christie, Cecilia J. Hillard, Alan J. Budney, Ryan G. Vandrey, Trevor Robbins, Paolo Nencini, Michele Stanislaw Milella, Naheed (Max) Mirza, Victoria L Harvey, Tony Dickenson, Seiya Miyamoto, Osborne Almeida, Nuno Sousa, S Yu, Anthony Absalom, David Menon, Pedro L. Delgado, Cyril Höschl, Tara L White, Richard Depue, Christof Baltes, Thomas Mueggler, Markus Rudin, Peter J Flor, Inga Neumann, Craig A Erickson, David J Posey, Kelly Blankenship, Kimberly A Stigler, Christopher J. McDougle, Etienne Sibille, Nicole Edgar, Malcolm Lader, Theodora Duka, Emma Childs, Britta Hahn, Jaanus Harro, Paul Newhouse, Heather Wilkins, Yesne Alici, William Breitbart, Eric Nestler, Anthony R Isles, Lawrence Wilkinson, Subhash Pandey, Samuel G. Siris, Paul Willner, Michel Billiard, Björn Lemmer, Jean-Michel Scherrmann, Lawrence H. Price, Tomek J Banasikowski, Richard J Beninger, John Harvey, Brian E. Leonard, Kim Wolff, Ashwini Padhi, Naomi Fineberg, Warren H Meck, Catalin V Buhushi, Lance Richard McMahon, Yogita Chudasama, Michael Kuhar, Joachim D. Uys, Peter W. Kalivas, Mohammed Shoaib, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Michael Bloch, James F Leckman, Barbara J. Sahakian, Sharon Morein-Zamir, Anne Jackson, Ben J Harrison, Christos Pantelis, Ian Hindmarch, Alyson J Bond, Jaime M Monti, Darren R Christensen, Warren K. Bickel, Marcy J Bubar, Kathryn A Cunningham, Christine A Franco, Marc Potenza, Maria-Inés López-Ibor, Juan J López-Ibor, Joseph H Friedman, Alex Hofer, Tomek J. Banasikowski, Richard J. Beninger, Matthew I Palmatier, Rick A Bevins, Thomas Tzschentke, David Roberts, Stephan Anagnostaras, Jennifer R Sage, Stephanie A Carmack, Stephen J. Kohut, Anthony L. Riley, Ronald F. Mucha, Jos Prickaerts, Oliver Stiedl, Sven Ove Ögren, Karim Nader, Oliver Hardt, Paola V. Migues, Arthur Christopoulos, Gregory D Stewart, Patrick M Sexton, Yavin Shaham, Sunila G Nair, Sarah H Heil, Stacey C Sigmon, Stephen T. Higgins, Sarah H. Heil, Stacey C. Sigmon, Marc N Branch, Mary Cain, Michael T Bardo, Robert L Balster, Sharon Walsh, Roel de Rijk, Ronald De Kloet, Chase H. Bourke, Michael J. Owens, Cécile Viollet, Jacques Epelbaum, Karl Mann, Falk Kiefer, Michael Owens, Chase Bourke, Hamish McAllister-Williams, Andreas Marneros, Rodrigo Andrade, Ivan Izquierdo, Lia Rejane M Bevilaqua, Martin Cammarota, Christoph Hiemke, Maria Isabel Colado, and Richard Green
Published: 2010
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45. AIF

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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46. Autism: Animal Models

Author: Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Alfonso Abizaid, Shimon Amir, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Christopher L. Cunningham, Yesne Alici, William Breitbart, Subhash C. Pandey, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Lawrence H. Price, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Elizabeth C. Warburton, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, W. Wolfgang Fleischhacker, Samuel B. Hutton, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Tim C. Kirkham, Ronald F. Mucha, Cecilia J. Hillard, Fiona Thomson, Susan Napier, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul B. S. Clarke, Luis de Lecea, Samuel R. Chamberlain, Barbara J. Sahakian, Martin Sarter, Andrea Bari, Matt Field, Ingmar H. A. Franken, Warren H. Meck, Catalin V. Buhusi, Kim Fromme, Amee B. Patel, David S. Tait, Verity J. Brown, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Tomasz Schneider, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Ennio Esposito, Roberto William Invernizzi, Oliver Stiedl, and Sven Ove Ögren
Published: 2010
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47. Short Interfering RNA

Author: Michael M. Morgan, MacDonald J. Christie, Luis De Lecea, Jason C. G. Halford, Josee E. Leysen, Warren H. Meck, Catalin V. Buhusi, Marcy J. Bubar, Kathryn A. Cunningham, Richard W. Foltin, David C. S. Roberts, Andreas Marneros, Alex Hofer, Bart Ellenbroek, Christoph U. Correll, Paul Newhouse, Heather Wilkins, Joris C. Verster, Emma Childs, Gary Remington, Edoardo Spina, W. Wolfgang Fleischhacker, John Atack, Hilde Lavreysen, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Dan J. Stein, Anthony L. Riley, Steve Kohut, Angela Roberts, Marilyn E. Carroll, Peter A. Santi, Stefan Leucht, Klaus A. Miczek, Eileen M. Joyce, Jonathan P. Roiser, Celia J. A. Morgan, Valerie H. Curran, Mary E. Cain, Michael T. Bardo, Terry E. Robinson, Ian Hindmarch, Darrell D. Mousseau, Andrew Holt, Glen B. Baker, Sidney H. Kennedy, Sakina J. Rizvi, Thomas Steckler, Seiya Miyamoto, Sakire Pogun, Gorkem Yararbas, Jill B. Becker, Anders Ågmo, Vera Astreika, Robert Segraves, Rodrigo Andrade, Yogita Chudasama, Roshan Cools, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Bernard Le Foll, Trevor W. Robbins, Husseini K. Manji, Jorge A. Quiroz, Jos Prickaerts, Ennio Esposito, William Invernizzi, Sophie Tambour, John C. Crabbe, Peter J. Flor, Inga D. Neumann, Malcolm Lader, Joseph Zohar, Seithikurippu R. Pandi-Perumal, Milton Kramer, Michael J. Thorpy, Shelby Freedman Harris, D. Warren Spence, Gabriele Fischer, Annemarie Unger, Samuel B. Hutton, Huaiyu Yang, George I. Papakostas, S. Kasper, Frank Sams-Dodd, Yavin Shaham, John R. Mantsch, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Paul D. Callaghan, Iain S. McGregor, Murray R. Thompson, Michel Billiard, Brian A. Fallon, Kelli J. Harding, Daniel Hoyer, Jacques Epelbaum, Cécile Viollet, Mischa de Rover, Sander Nieuwenhuis, Stan Floresco, Anne Jackson, Mitul A. Mehta, Johannes Mosbacher, Ronald L. Cowan, Robert Kessler, Peter H. Boeijinga, James Winslow, A. Claudio Cuello, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Ashwini Padhi, Naomi A. Fineberg, Mark A. Geyer, Francis C. Colpaert, Andrew Young, Ronald F. Mucha, Christof Baltes, Thomas Mueggler, Markus Rudin, Giovanni Hernandez, Peter Shizgal, Marc N. Branch, Ian P. Stolerman, Sharon Morein-Zamir, Barbara J. Sahakian, Sunila G. Nair, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, R. H. De Rijk, E. R. de Kloet, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Maria Isabel Colado, A. Richard Green, Suzanne H. Mitchell, Harriet de Wit, Alyson J. Bond, Christine A. Franco, Marc N. Potenza, Caroline Cohen, Marc Turiault, Guy Griebel, Darren R. Christensen, Warren K. Bickel, Michael J. Owens, Chase H. Bourke, Gustavo Turecki, Britta Hahn, Sarah Morgan, Angus Mackay, Matthew I. Palmatier, Rick A. Bevins, Lawrence Scahill, Andrea Bari, Stephen B. Dunnett, Karim Nader, Oliver Hardt, Paola V. Migues, R. Andrew Chambers, and David E. Nichols
Published: 2010
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48. CST

Author: Daniel Hoyer, Eric P Zorrilla, Pietro Cottone, Sarah Parylak, Micaela Morelli, Nicola Simola, James D. Lane, Michael M Morgan, M J Christie, Cecilia J. Hillard, Alan J. Budney, Ryan G. Vandrey, Trevor Robbins, Paolo Nencini, Michele Stanislaw Milella, Naheed (Max) Mirza, Victoria L Harvey, Tony Dickenson, Seiya Miyamoto, Osborne Almeida, Nuno Sousa, S Yu, Anthony Absalom, David Menon, Pedro L. Delgado, Cyril Höschl, Tara L White, Richard Depue, Christof Baltes, Thomas Mueggler, Markus Rudin, Peter J Flor, Inga Neumann, Craig A Erickson, David J Posey, Kelly Blankenship, Kimberly A Stigler, Christopher J. McDougle, Etienne Sibille, Nicole Edgar, Malcolm Lader, Theodora Duka, Emma Childs, Britta Hahn, Jaanus Harro, Paul Newhouse, Heather Wilkins, Yesne Alici, William Breitbart, Eric Nestler, Anthony R Isles, Lawrence Wilkinson, Subhash Pandey, Samuel G. Siris, Paul Willner, Michel Billiard, Björn Lemmer, Jean-Michel Scherrmann, Lawrence H. Price, Tomek J Banasikowski, Richard J Beninger, John Harvey, Brian E. Leonard, Kim Wolff, Ashwini Padhi, Naomi Fineberg, Warren H Meck, Catalin V Buhushi, Lance Richard McMahon, Yogita Chudasama, Michael Kuhar, Joachim D. Uys, Peter W. Kalivas, Mohammed Shoaib, Daniel Bertrand, Hans Rollema, Raymond S Hurst, Michael Bloch, James F Leckman, Barbara J. Sahakian, Sharon Morein-Zamir, Anne Jackson, Ben J Harrison, Christos Pantelis, Ian Hindmarch, Alyson J Bond, Jaime M Monti, Darren R Christensen, Warren K. Bickel, Marcy J Bubar, Kathryn A Cunningham, Christine A Franco, Marc Potenza, Maria-Inés López-Ibor, Juan J López-Ibor, Joseph H Friedman, Alex Hofer, Tomek J. Banasikowski, Richard J. Beninger, Matthew I Palmatier, Rick A Bevins, Thomas Tzschentke, David Roberts, Stephan Anagnostaras, Jennifer R Sage, Stephanie A Carmack, Stephen J. Kohut, Anthony L. Riley, Ronald F. Mucha, Jos Prickaerts, Oliver Stiedl, Sven Ove Ögren, Karim Nader, Oliver Hardt, Paola V. Migues, Arthur Christopoulos, Gregory D Stewart, Patrick M Sexton, Yavin Shaham, Sunila G Nair, Sarah H Heil, Stacey C Sigmon, Stephen T. Higgins, Sarah H. Heil, Stacey C. Sigmon, Marc N Branch, Mary Cain, Michael T Bardo, Robert L Balster, Sharon Walsh, Roel de Rijk, Ronald De Kloet, Chase H. Bourke, Michael J. Owens, Cécile Viollet, Jacques Epelbaum, Karl Mann, Falk Kiefer, Michael Owens, Chase Bourke, Hamish McAllister-Williams, Andreas Marneros, Rodrigo Andrade, Ivan Izquierdo, Lia Rejane M Bevilaqua, Martin Cammarota, Christoph Hiemke, Maria Isabel Colado, and Richard Green
Published: 2010
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49. BOLD Contrast

Author: Peter J. Tyrer, Mark Slifstein, Joris C. Verster, Kim Fromme, Amee B. Patel, Britta Hahn, Christer Allgulander, A. Claudio Cuello, Giovanni Hernandez, Peter Shizgal, Irwin Lucki, Warren K. Bickel, Darren R. Christensen, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Verity J. Brown, David S. Tait, Andrea Bari, Gorkem Yararbas, Sakire Pogun, Richard W. Foltin, Harriet de Wit, Daniel Hoyer, David Nutt, Gessica Sala, Lucio Tremolizzo, Carlo Ferrarese, Eric P. Zorrilla, Pietro Cottone, Sarah Parylak, Anne M. Andrews, Greg A. Gerhardt, Lynette C. Daws, R. H. Belmaker, Tiffany Thomas, Robert L. Findling, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Helen J. Cassaday, Seiya Miyamoto, Jean-Michel Scherrmann, Michael J. Owens, Chase H. Bourke, Martina de Zwaan, Christof Baltes, Thomas Mueggler, Markus Rudin, Debby Van Dam, Peter Paul De Deyn, Joseph H. Friedman, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, David S. Middlemas, David B. Bylund, David C. S. Roberts, Emma Childs, Naheed (Max) Mirza, Lance R. McMahon, Linda Dykstra, Gabriele Fischer, Annemarie Unger, Mohammed Shoaib, David S. Baldwin, and W. Wolfgang Fleischhacker
Published: 2010
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50. Bulimia Nervosa

Author: Peter J. Tyrer, Mark Slifstein, Joris C. Verster, Kim Fromme, Amee B. Patel, Britta Hahn, Christer Allgulander, A. Claudio Cuello, Giovanni Hernandez, Peter Shizgal, Irwin Lucki, Warren K. Bickel, Darren R. Christensen, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Verity J. Brown, David S. Tait, Andrea Bari, Gorkem Yararbas, Sakire Pogun, Richard W. Foltin, Harriet de Wit, Daniel Hoyer, David Nutt, Gessica Sala, Lucio Tremolizzo, Carlo Ferrarese, Eric P. Zorrilla, Pietro Cottone, Sarah Parylak, Anne M. Andrews, Greg A. Gerhardt, Lynette C. Daws, R. H. Belmaker, Tiffany Thomas, Robert L. Findling, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Helen J. Cassaday, Seiya Miyamoto, Jean-Michel Scherrmann, Michael J. Owens, Chase H. Bourke, Martina de Zwaan, Christof Baltes, Thomas Mueggler, Markus Rudin, Debby Van Dam, Peter Paul De Deyn, Joseph H. Friedman, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, David S. Middlemas, David B. Bylund, David C. S. Roberts, Emma Childs, Naheed (Max) Mirza, Lance R. McMahon, Linda Dykstra, Gabriele Fischer, Annemarie Unger, Mohammed Shoaib, David S. Baldwin, and W. Wolfgang Fleischhacker
Published: 2010
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