Search

Your search keyword '"Charles S. Schwender"' showing total 2 results
Start Over Author "Charles S. Schwender"
2 results on '"Charles S. Schwender"'

1. Preparation of benzo[c][2,7]naphthyridin-5(1H)-ones as analogs of benzopyrano[3,4-c]pyridin-5-one bronchodilators

Author

Richard E. Brown, Mary E. Carethers, Chester Puchalski, David T. Connor, Paul C. Unangst, and Charles S. Schwender

Subjects
chemistry.chemical_compound, Stereochemistry, Chemistry, Methyl Ketone, Organic Chemistry, Anticholinergic bronchodilators, Lactam, Nuclear magnetic resonance spectroscopy, Alkylation, Ring (chemistry), Reductive amination
Abstract

A series of 2,3,4,6-tetrahydro-8,9-dimethoxybenzo[c][2,7]naphthyridin-5(1H)-ones was prepared as potential anticholinergic bronchodilators. The naphthyridine ring system was constructed by cyclization of a 3-amido-4-piperidone. Alkylation with alkylaminoethyl chlorides or reductive amination of an intermediate methyl ketone yielded the final target compounds.

Published
1986
Full Text
View/download PDF

2. ChemInform Abstract: Preparation of Benzo(c)(2,7)naphthyridin-5(1H)-ones as Analogs of Benzopyrano(3,4-c)pyridin-5-one Bronchodilators

Author

Chester Puchalski, David T. Connor, Paul C. Unangst, Mary E. Carethers, Richard E. Brown, and Charles S. Schwender

Subjects
Chemistry, Methyl Ketone, Anticholinergic bronchodilators, General Medicine, Alkylation, Ring (chemistry), Medicinal chemistry, Reductive amination
Abstract

A series of 2,3,4,6-tetrahydro-8,9-dimethoxybenzo[c][2,7]naphthyridin-5(1H)-ones was prepared as potential anticholinergic bronchodilators. The naphthyridine ring system was constructed by cyclization of a 3-amido-4-piperidone. Alkylation with alkylaminoethyl chlorides or reductive amination of an intermediate methyl ketone yielded the final target compounds.

Published
1987
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results