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Fourth, the question of cost for the training programs needs to be addressed. TPD will have to use the same diverse mechanism now used to fund new programs. Namely, use of institutional funds, practice fees, industry support, private agency grants, and state and federal grants that may be available for the support of fellows. It is likely that establishment of formal training programs in CDL1 will enhance the opportunities for obtaining funding from these diverse sources.

Wind tunnel model studies of houses are used to determine how one can best reduce the surface pressure variations from wind and the associated air infiltration, emphasizing the correct placement of suitably modeled coniferous trees. The trees are shown to have energy-saving potential by converting directed kinetic energy of the approaching wind into random turbulent energy by passing the air through tortuous paths in the tree crowns. This reduces the pressure gradients on the windward walls which are a prime region for air infiltration. The most cost- and energy-effective windbreaks are those that selectively protect against the prevailing winter winds, use as few trees as possible, and are placed at least two tree heights upstream. Underpruning and poorly designed openings through the trees, such as driveway access, were shown to enhance air infiltration effects. Using as few as three trees, 3% fuel savings were estimated. When a planting pattern affording general protection was analyzed, it was estimated to achieve higher than 10% savings in energy for heating.

The effectiveness of the cytotoxic drug, cyclophosphamide, has been evaluated in 16 patients with refractory uveitis. Clinically significant suppression of inflammation occurred in nine of nine patients with peripheral uveitis. Results were less predictable in other forms of uveitis. Toxic side effects of cyclophosphamide were less than those reported with mercaptopurine and other metabolic inhibitors or those associated with long-term high dosage systemic steroid therapy. Combined steroid and cyclophosphamide therapy was most effective in suppressing inflammation. Cyclophosphamide decreased the risk of adverse effects of hypertension and diabetes in patients on prolonged steroid therapy. Lymphopenia with or without leukopenia correlated best with control of ocular inflammation. Cyclophosphamide is a potentially useful drug in the care of patients with significant autoallergic disease.