Search

Your search keyword '"Chardon, H."' showing total 142 results
Start Over Author "Chardon, H."
142 results on '"Chardon, H."'

1. Observatoires régionaux du pneumocoque : évolution de la résistance aux antibiotiques et des sérotypes de Streptococcus pneumoniae isolés en France entre 2009 et 2013

Author

Brieu, N., Varon, E., Baraduc, R., Brun, M., Chardon, H., Cremniter, J., Decousser, J.-W., Fosse, T., Gravet, A., Grelaud, C., Hadou, T., Hamdad, F., Labrunie, A., Lanotte, P., Luce, S., Patry, I., Péchinot, A., Pelloux, I., Raymond, J., Ros, A., Segonds, C., Soullié, B., Tandé, D., Vergnaud, M., Vernet-Garnier, V., Wallet, F., Gutmann, L., Lepoutre, A., Ploy, M.-C., and Kempf, M.

Published
2015
Full Text
View/download PDF

2. Decline in antibiotic resistance and changes in the serotype distribution of Streptococcus pneumoniae isolates from children with acute otitis media; a 2001–2011 survey by the French Pneumococcal Network

Author

Kempf, M., Varon, E., Lepoutre, A., Gravet, A., Baraduc, R., Brun, M., Chardon, H., Cremniter, J., Croizé, J., Dalmay, F., Demachy, M.-C., Fosse, T., Grelaud, C., Hadou, T., Hamdad, F., Koeck, J.-L., Luce, S., Mermond, S., Patry, I., Péchinot, A., Raymond, J., Ros, A., Segonds, C., Soullié, B., Tandé, D., Vergnaud, M., Vernet-Garnier, V., Wallet, F., Gutmann, L., Ploy, M.-C., and Lanotte, P.

Published
2015
Full Text
View/download PDF

8. Inventory of Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae in France as Assessed by a Multicenter Study

Author

Robin, F., primary, Beyrouthy, R., additional, Bonacorsi, S., additional, Aissa, N., additional, Bret, L., additional, Brieu, N., additional, Cattoir, V., additional, Chapuis, A., additional, Chardon, H., additional, Degand, N., additional, Doucet-Populaire, F., additional, Dubois, V., additional, Fortineau, N., additional, Grillon, A., additional, Lanotte, P., additional, Leyssene, D., additional, Patry, I., additional, Podglajen, I., additional, Recule, C., additional, Ros, A., additional, Colomb-Cotinat, M., additional, Ponties, V., additional, Ploy, M. C., additional, and Bonnet, R., additional

Published
2017
Full Text
View/download PDF

10. Diminution de la résistance aux antibiotiques des souches de Streptococcus pneumoniae isolées d’infections invasives en France entre 2005 et 2011 : résultats des Observatoires régionaux du pneumocoque (ORP)

Author

Kempf, M., Gravet, A, Baraduc, R, Brun, M., Chardon, H, Lanotte, Philippe, Varon, E, Ploy, M-C, Laboratoire de Bactériologie, Centre Hospitalier Victor Provo, CHU Limoges, Centre Hospitalier Emile Muller [Mulhouse] (CH E.Muller Mulhouse), Groupe Hospitalier de Territoire Haute Alsace (GHTHA), Infectiologie et Santé Publique (UMR ISP), Institut National de la Recherche Agronomique (INRA)-Université de Tours (UT), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), and Institut National de la Recherche Agronomique (INRA)-Université de Tours

Subjects
[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, ComputingMilieux_MISCELLANEOUS, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

National audience

Published
2012

11. Serotype distribution and antibiotic resistance of Streptococcus pneumoniae strains isolated from adults in France: evolution between 2001 and 2003

Author

Roussel-Delvallez, M., Vernet-Garnier, V., Bourdon, S., Brun, M., Cattier, B., Chanal, C., Chardon, H., Chomarat, M., Croize, J., Demachy, M.C., Donnio, P.Y., Dupont, Pierre, Fosse, T., Gravet, A., Grignon, B., Laurans, G., Maugein, J., Pechinot, A., Prere, M.F., Thoreux, P.H., Vergnaud, M., Weber, M., Coignard, B., Gutmann, L., Ploy, Marie-Cécile, Laboratoire de microbiologie et génétique moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)

Subjects
ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2009

12. Antimicrobial resistance data on 16,756 Streptococcus pneumoniae isolates in 1999: A pan-regional multicenter surveillance study in France

Author

Demachy, M.C., Vernet-Garnier, V., Cottin, J., Chanal, C., Chardon, H., Chomarat, M., Dupont, Pierre, Fauchère, J.L., Fosse, T., Laaberki, M.F., Laurens, G., Lemozy, J., Maugein, J., Murbach, V., Roussel-Delvallez, M., Thoreux, P.H., Vaucel, J., Vergnaud, M., Weber, M., Ploy, Marie-Cécile, Biologie moléculaire et cellulaire des microorganismes (EA3175), Université de Limoges (UNILIM)-Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST FR CNRS 3503)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Limoges (UNILIM), and Bucek, Ingrid

Subjects
[SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2005

19. Observatoires régionaux du pneumocoque : évolution de la résistance aux antibiotiques et des sérotypes de Streptococcus pneumoniaeisolés en France entre 2009 et 2013

Author

Brieu, N., Varon, E., Baraduc, R., Brun, M., Chardon, H., Cremniter, J., Decousser, J.-W., Fosse, T., Gravet, A., Grelaud, C., Hadou, T., Hamdad, F., Labrunie, A., Lanotte, P., Luce, S., Patry, I., Péchinot, A., Pelloux, I., Raymond, J., Ros, A., Segonds, C., Soullié, B., Tandé, D., Vergnaud, M., Vernet-Garnier, V., Wallet, F., Gutmann, L., Lepoutre, A., Ploy, M.-C., and Kempf, M.

Abstract

La surveillance de l’évolution de la résistance aux antibiotiques et des sérotypes des souches de Streptococcus pneumoniaeen France repose sur un réseau alliant les observatoires du pneumocoque, le Centre national de référence du pneumocoque et l’Institut de veille sanitaire.

Published
2015
Full Text
View/download PDF

24. Observatoire régional du pneumocoque. Bilan 1995 de la région provençale

Author

May, C., primary, Bellon, O., additional, Lagier, E., additional, Lefrand, H., additional, Brisou, P., additional, Michel Nguyen, A., additional, Bietrix, M., additional, Duluc, F., additional, Durand, F., additional, Rousselier, P., additional, Bertrand, J.J., additional, Lacombe, M.F., additional, Payen, C., additional, Carrere, J., additional, Cordoleani, B., additional, Merabet, A., additional, Collet, L., additional, Geslin, P., additional, and Chardon, H., additional

Published
1997
Full Text
View/download PDF

29. Intrathecal zidovudine for AIDS dementia

Author

Routy, J.P., primary, Blanc, A.P., additional, Rodriguez, E., additional, Escoffier, M., additional, Joliot, Y., additional, Kiegel, P., additional, Viallet, F., additional, and Chardon, H., additional

Published
1990
Full Text
View/download PDF

30. Epidemiology of antibiotic resistant pneumococci

Author

Chardon, H., Varon, E., Bensaid, T., Bellon, O., Lagier, E., and Gutmann, L.

Subjects
*STREPTOCOCCUS pneumoniae, *EPIDEMIOLOGY, *ANTIBIOTICS
Abstract

Streptococcus pneumoniae may be considered like multiresistant bacteria, responsible for non-nosocomial infections. In France during 1999, 44 % of the strains were non-susceptible to penicillin G (PNSP) (with 12 % of resistant strains), 26 % were non-susceptible to amoxicilline (with 1,8 % of resistant strains) and 17,1% were non-susceptible to cefotaxime (with 0,4 % of resistant strains). The percentage of resistant strains was 1.8 % for amoxicilline and 0.4 % for cefotaxime. The PNSP''s percentage was variable with regions, from 32 % in the “Pays de Loire” to 60 % in “Brie”. It was higher for children (52.7 %) than for adults (39.8 %). It was also a function of sample''s site and age (child/adult): bloodstream 41.8 % / 37.2 %, broncho-pulmonary sample 54.2 % / 41.4 %, and cerebrospinal fluid 45.5 % / 37.5 %. These PNSP were often poly-resistant : 30.1 % of penicillin susceptible pneumococci but 82.2 % of the PNSP were resistant to erythromycin''s. In children, the percentage of erythromycin''s resistant pneumococci was about 73.2 % for ears, 66 % for broncho-pulmonary, 50.2 % for bloodstream and 56.3 % in cerebrospinal fluid. The most common serotype for PNSP strains was the 23 serotype. Lastly, for anti-pneumococci fluoroquinolones, few resistant strains have been mentioned. [Copyright &y& Elsevier]

Published
2002

31. Killing kinetics of five orally administered antibiotics at clinically achievable concentrations against moraxella catarrhalis.

Author

Bingen, E., Bourgeois, F., Chardon, H., Doit, C., and Lambert-Zechovsky, N.

Abstract

Time-kill kinetic studies were used to measure the bactericidal activity of amoxicillin/clavulanic acid (in a new form for pediatric use), cefaclor, cefuroxime, cefixime and erythromycin against 30 beta-lactamase producing Moraxella catarrhalis strains. Antibiotics were tested at the mean maximum serum concentration observed after administration of a standard dose and at 0.5 × Cmax, 0.33 × Cmax and 0.25 × Cmax. A 2 log10 reduction in colony counts was obtained with the Cmax of amoxicillin/clavulanic acid and cefixime after 5 h of incubation. After 24 h of incubation a decrease of 3 and 4 log was observed with cefixime and amoxicillin/clavulanic acid respectively. At 0.5 × Cmax and 0.33 × Cmax, bactericidal activity was obtained only with amoxicillin/clavulanic acid. [ABSTRACT FROM AUTHOR]

Published
1992
Full Text
View/download PDF

33. New Plasmid-Mediated Nucleotidylation of Aminoglycoside Antibiotics in Staphylococcus aureus

Author

Goffic, F. Le, Martel, A., Capmau, M. L., Baca, B., Goebel, P., Chardon, H., Soussy, C. J., Duval, J., and Bouanchaud, D. H.

Abstract

A wild-type strain of Staphylococcus aureus, which inactivates a wide variety of aminoglycosides (except the gentamicin components), has been found to harbor a plasmid (RAp01) that mediates the biosynthesis of a nucleotidyltransferase. This enzyme modifies the 4′-hydroxy function of these antibiotics. The plasmid has been studied, the enzyme responsible for this resistance pattern has been isolated by affinity chromatography, and its kinetics and physicochemistry have been characterized. The target of this enzyme has also been located by demonstrating the structure of one inactivated compound, 4′-(O)-adenylyltobramycin.

Published
1976
Full Text
View/download PDF

44. Etude multicentrique de la resistance a la pefloxacine dans 16 hopitaux generaux, chez Staphylococcus aureus, Citrobacter, Serratia, Enterobacter, Proteus indole plus, Pseudomonas aeruginosa et Acinetobacter

Author

Boisivon, A., primary, Berardi-Grassias, L., additional, Bietrix, M., additional, Briffod, J., additional, Chardon, H., additional, Croix, J.C., additional, Delbecke, E., additional, Gauthier, C., additional, Lionsquy, G., additional, Martelli, J.M., additional, Melon, M., additional, Prieur, D., additional, Roger, F., additional, Trevoux, A., additional, Tourrand, B., additional, and Vaucel, J.C., additional

Published
1988
Full Text
View/download PDF

47. Inventory of Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceaein France as Assessed by a Multicenter Study

Author

Robin, F., Beyrouthy, R., Bonacorsi, S., Aissa, N., Bret, L., Brieu, N., Cattoir, V., Chapuis, A., Chardon, H., Degand, N., Doucet-Populaire, F., Dubois, V., Fortineau, N., Grillon, A., Lanotte, P., Leyssene, D., Patry, I., Podglajen, I., Recule, C., Ros, A., Colomb-Cotinat, M., Ponties, V., Ploy, M. C., and Bonnet, R.

Abstract

ABSTRACTThe objective of this study was to perform an inventory of the extended-spectrum-β-lactamase (ESBL)-producing Enterobacteriaceaeisolates responsible for infections in French hospitals and to assess the mechanisms associated with ESBL diffusion. A total of 200 nonredundant ESBL-producing Enterobacteriaceaestrains isolated from clinical samples were collected during a multicenter study performed in 18 representative French hospitals. Antibiotic resistance genes were identified by PCR and sequencing experiments. The clonal relatedness between isolates was investigated by the use of the DiversiLab system. ESBL-encoding plasmids were compared by PCR-based replicon typing and plasmid multilocus sequence typing. CTX-M-15, CTX-M-1, CTX-M-14, and SHV-12 were the most prevalent ESBLs (8% to 46.5%). The three CTX-M-type EBSLs were significantly observed in Escherichia coli(37.1%, 24.2%, and 21.8%, respectively), and CTX-M-15 was the predominant ESBL in Klebsiella pneumoniae(81.1%). SHV-12 was associated with ESBL-encoding Enterobacter cloacaestrains (37.9%). qnrB, aac(6′)-Ib-cr, and aac(3)-IIgenes were the main plasmid-mediated resistance genes, with prevalences ranging between 19.5% and 45% according to the ESBL results. Molecular typing did not identify wide clonal diffusion. Plasmid analysis suggested the diffusion of low numbers of ESBL-encoding plasmids, especially in K. pneumoniaeand E. cloacae. However, the ESBL-encoding genes were observed in different plasmid replicons according to the bacterial species. The prevalences of ESBL subtypes differ according to the Enterobacteriaceaespecies. Plasmid spread is a key determinant of this epidemiology, and the link observed between the ESBL-encoding plasmids and the bacterial host explains the differences observed in the Enterobacteriaceaespecies.

Published
2017
Full Text
View/download PDF

50. Susceptibility of Enterobacteriaceae toβ -lactam agents and fluoroquinolones: a 3-year survey in France.

Author

Sirot, J, Nicolas-Chanoine, M. H, Chardon, H, Avril, J. L, Cattoen, C, Croix, J. C, Dabernat, H, Fosse, T, Ghnassia, J. C, Lecaillon, Marmonier, A, Roussel-Delvallez, M, Soussy, C. J, Trevoux, A, Vandenesch, F, Dib, C, Moniot-Ville, N, and Rezvani, Y

Subjects
*ENTEROBACTERIACEAE, *BETA lactamases, *HOSPITALS
Abstract

Objective: To assess trends in the susceptibility to β -lactam agents and to fluoroquinolones of clinically relevant Enterobacteriaceae isolated over a 3-year period in 14 French hospital laboratories. Methods: During the second quarter of 1996, 1997 and 1998, 180 consecutive non-duplicate isolates of Enterobacteriaceae were collected in each center. Sixteen β -lactams and four quinolones were tested by the disk diffusion method. In addition, the double-disk synergy test was used to screen for the production of extended-spectrum β -lactamase (ESBL). Results: Totals of 2507, 2312 and 2506 clinical isolates were obtained in each period, respectively. The distribution of Enterobacteriaceae species according to clinical specimens and wards was similar in each study period. No significant variation in the susceptibility rates to β -lactams and fluoroquinolones was observed, except in Klebsiella pneumoniae and Enterobacter aerogenes. The prevalence of ESBL-producing isolates decreased from 18% to 9% in the former, while it increased from 32% to 54% in the latter. At the same time, the susceptibility to ofloxacin and pefloxacin increased for K. pneumoniae (P < 0.003) and cephalosporinase-producing species (P < 0.05), except Enterobacter spp. Conclusion: Over the 3-year study period β -lactams and fluoroquinolones remained highly active against Enterobacteriaceae clinical isolates, with the exception of E. aerogenes , probably as a result of the dissemination of multiresistant clones in French hospitals. [ABSTRACT FROM AUTHOR]

Published
2002
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results