1,827 results on '"Chapman, N"'
Search Results
2. Spatial analysis of murine microbiota and bile acid metabolism during amoxicillin treatment
- Author
-
Beekman, Chapman N., Penumutchu, Swathi, Peterson, Rachel, Han, Geongoo, Belenky, Marina, Hasan, Mohammad H., Belenky, Alexei, Beura, Lalit K., and Belenky, Peter
- Published
- 2024
- Full Text
- View/download PDF
3. The role of the magnetic field in the fragmentation process: the case of G14.225-0.506
- Author
-
Añez-López, N., Busquet, G., Koch, P. M., Girart, J. M., Liu, H. B., Santos, F., Chapman, N. L., Novak, G., Palau, A., Ho, P. T. P., and Zhang, Q.
- Subjects
Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
B-fields are predicted to play a role in the formation of filamentary structures and their fragmentation process. We aim at investigating the role of the B-field in the process of core fragmentation toward the hub-filament systems in the IRDC G14.2, which present different fragmentation level. We performed observations of the thermal dust polarization at 350 {\mu}m using the CSO toward the hubs. We applied the polarization--intensity-gradient method to estimate the significance of the B-field over the G-force. The B-field in Hub-N shows a uniform structure along the E-W orientation, perpendicular to the major axis of the hub-filament system. The I-gradient in Hub-N displays a local minimum coinciding with the dust core MM1a detected with interferometric observations. The B-field orientation is perturbed when approaching the dust core. Hub-S shows 2 local minima, reflecting the bimodal distribution of the B-field. In Hub-N, both E and W of the hub-filament system, the I-gradient and the B-field are parallel whereas they tend to be perpendicular when penetrating the filaments and hub. The analysis of the {\delta}- and {\Sigma} B-maps indicate that, the B-field cannot prevent the collapse, suggesting that the B-field is initially dragged by the infalling motion and aligned with it, or is channeling material toward the central ridge from both sides. Values of {\Sigma} B > 1 are found toward a N-S ridge encompassing the dust emission peak, indicating that in this region B-field dominates over G-force, or that with the current angular resolution we cannot resolve an hypothetical more complex structure. We estimated the B-field strength, the MtF ratio and the A-M number, and found differences between the 2 hubs. The different levels of fragmentation observed in these 2 hubs could arise from the differences in the B-field properties rather than from different intensity of the G-field., Comment: 14 pages, 9 figures
- Published
- 2020
- Full Text
- View/download PDF
4. Management of patients with hypertension and chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. On behalf of the European Society of Hypertension Working Group on Hypertension and the Kidney
- Author
-
Halimi, J, Sarafidis, P, Azizi, M, Bilo, G, Burkard, T, Bursztyn, M, Camafort, M, Chapman, N, Cottone, S, de Backer, T, Deinum, J, Delmotte, P, Dorobantu, M, Doumas, M, Dusing, R, Duly-Bouhanick, B, Fauvel, J, Fesler, P, Gaciong, Z, Gkaliagkousi, E, Gordin, D, Grassi, G, Grassos, C, Guerrot, D, Huart, J, Izzo, R, Jaén Águila, F, Járai, Z, Kahan, T, Kantola, I, Kociánová, E, Limbourg, F, Lopez-Sublet, M, Mallamaci, F, Manolis, A, Marketou, M, Mayer, G, Mazza, A, Macintyre, I, Mourad, J, Muiesan, M, Nasr, E, Nilsson, P, Oliveras, A, Ormezzano, O, Paixão-Dias, V, Papadakis, I, Papadopoulos, D, Perl, S, Polónia, J, Pontremoli, R, Pucci, G, Robles, N, Rubin, S, Ruilope, L, Rump, L, Saeed, S, Sanidas, E, Sarzani, R, Schmieder, R, Silhol, F, Sokolovic, S, Solbu, M, Soucek, M, Stergiou, G, Sudano, I, Tabbalat, R, Tengiz, I, Triantafyllidi, H, Tsioufis, K, Václavík, J, van der Giet, M, der Niepen, P, Veglio, F, Venzin, R, Viigimaa, M, Weber, T, Widimsky, J, Wuerzner, G, Zelveian, P, Zebekakis, P, Lueders, S, Persu, A, Kreutz, R, Vogt, L, Halimi JM, Sarafidis P, Azizi M, Bilo G, Burkard T, Bursztyn M, Camafort M, Chapman N, Cottone S, de Backer T, Deinum J, Delmotte P, Dorobantu M, Doumas M, Dusing R, Duly-Bouhanick B, Fauvel JP, Fesler P, Gaciong Z, Gkaliagkousi E, Gordin D, Grassi G, Grassos C, Guerrot D, Huart J, Izzo R, Jaén Águila F, Járai Z, Kahan T, Kantola I, Kociánová E, Limbourg F, Lopez-Sublet M, Mallamaci F, Manolis A, Marketou M, Mayer G, Mazza A, MacIntyre I, Mourad JJ, Muiesan ML, Nasr E, Nilsson P, Oliveras A, Ormezzano O, Paixão-Dias V, Papadakis I, Papadopoulos D, Perl S, Polónia J, Pontremoli R, Pucci G, Robles NR, Rubin S, Ruilope LM, Rump LC, Saeed S, Sanidas E, Sarzani R, Schmieder R, Silhol F, Sokolovic S, Solbu M, Soucek M, Stergiou G, Sudano I, Tabbalat R, Tengiz I, Triantafyllidi H, Tsioufis K, Václavík J, van der Giet M, der Niepen PV, Veglio F, Venzin R, Viigimaa M, Weber T, Widimsky J, Wuerzner G, Zelveian P, Zebekakis P, Lueders S, Persu A, Kreutz R, Vogt L., Halimi, J, Sarafidis, P, Azizi, M, Bilo, G, Burkard, T, Bursztyn, M, Camafort, M, Chapman, N, Cottone, S, de Backer, T, Deinum, J, Delmotte, P, Dorobantu, M, Doumas, M, Dusing, R, Duly-Bouhanick, B, Fauvel, J, Fesler, P, Gaciong, Z, Gkaliagkousi, E, Gordin, D, Grassi, G, Grassos, C, Guerrot, D, Huart, J, Izzo, R, Jaén Águila, F, Járai, Z, Kahan, T, Kantola, I, Kociánová, E, Limbourg, F, Lopez-Sublet, M, Mallamaci, F, Manolis, A, Marketou, M, Mayer, G, Mazza, A, Macintyre, I, Mourad, J, Muiesan, M, Nasr, E, Nilsson, P, Oliveras, A, Ormezzano, O, Paixão-Dias, V, Papadakis, I, Papadopoulos, D, Perl, S, Polónia, J, Pontremoli, R, Pucci, G, Robles, N, Rubin, S, Ruilope, L, Rump, L, Saeed, S, Sanidas, E, Sarzani, R, Schmieder, R, Silhol, F, Sokolovic, S, Solbu, M, Soucek, M, Stergiou, G, Sudano, I, Tabbalat, R, Tengiz, I, Triantafyllidi, H, Tsioufis, K, Václavík, J, van der Giet, M, der Niepen, P, Veglio, F, Venzin, R, Viigimaa, M, Weber, T, Widimsky, J, Wuerzner, G, Zelveian, P, Zebekakis, P, Lueders, S, Persu, A, Kreutz, R, Vogt, L, Halimi JM, Sarafidis P, Azizi M, Bilo G, Burkard T, Bursztyn M, Camafort M, Chapman N, Cottone S, de Backer T, Deinum J, Delmotte P, Dorobantu M, Doumas M, Dusing R, Duly-Bouhanick B, Fauvel JP, Fesler P, Gaciong Z, Gkaliagkousi E, Gordin D, Grassi G, Grassos C, Guerrot D, Huart J, Izzo R, Jaén Águila F, Járai Z, Kahan T, Kantola I, Kociánová E, Limbourg F, Lopez-Sublet M, Mallamaci F, Manolis A, Marketou M, Mayer G, Mazza A, MacIntyre I, Mourad JJ, Muiesan ML, Nasr E, Nilsson P, Oliveras A, Ormezzano O, Paixão-Dias V, Papadakis I, Papadopoulos D, Perl S, Polónia J, Pontremoli R, Pucci G, Robles NR, Rubin S, Ruilope LM, Rump LC, Saeed S, Sanidas E, Sarzani R, Schmieder R, Silhol F, Sokolovic S, Solbu M, Soucek M, Stergiou G, Sudano I, Tabbalat R, Tengiz I, Triantafyllidi H, Tsioufis K, Václavík J, van der Giet M, der Niepen PV, Veglio F, Venzin R, Viigimaa M, Weber T, Widimsky J, Wuerzner G, Zelveian P, Zebekakis P, Lueders S, Persu A, Kreutz R, and Vogt L.
- Abstract
Objective Real-life management of patients with hypertension and chronic kidney disease (CKD) among European Society of Hypertension Excellence Centres (ESH-ECs) is unclear : we aimed to investigate it. Methods A survey was conducted in 2023. The questionnaire contained 64 questions asking ESH-ECs representatives to estimate how patients with CKD are managed. Results Overall, 88 ESH-ECS representatives from 27 countries participated. According to the responders, renin-angiotensin system (RAS) blockers, calcium-channel blockers and thiazides were often added when these medications were lacking in CKD patients, but physicians were more prone to initiate RAS blockers (90% [interquartile range: 70–95%]) than MRA (20% [10–30%]), SGLT2i (30% [20–50%]) or (GLP1-RA (10% [5–15%]). Despite treatment optimisation, 30% of responders indicated that hypertension remained uncontrolled (30% (15–40%) vs 18% [10%–25%]) in CKD and CKD patients, respectively). Hyperkalemia was the most frequent barrier to initiate RAS blockers, and dosage reduction was considered in 45% of responders when kalaemia was 5.5–5.9 mmol/L. Conclusions RAS blockers are initiated in most ESH-ECS in CKD patients, but MRA and SGLT2i initiations are less frequent. Hyperkalemia was the main barrier for initiation or adequate dosing of RAS blockade, and RAS blockers’ dosage reduction was the usual management.
- Published
- 2024
5. Screening and management of hypertensive patients with chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. A pilot survey based on questionnaire
- Author
-
Halimi, J, Sarafidis, P, Azizi, M, Bilo, G, Burkard, T, Bursztyn, M, Camafort, M, Chapman, N, Cottone, S, de Backer, T, Deinum, J, Delmotte, P, Dorobantu, M, Doumas, M, Dusing, R, Duly-Bouhanick, B, Fauvel, J, Fesler, P, Gaciong, Z, Gkaliagkousi, E, Gordin, D, Grassi, G, Grassos, C, Guerrot, D, Huart, J, Izzo, R, Águila, F, Járai, Z, Kahan, T, Kantola, I, Kociánová, E, Limbourg, F, Lopez-Sublet, M, Mallamaci, F, Manolis, A, Marketou, M, Mayer, G, Mazza, A, Macintyre, I, Mourad, J, Muiesan, M, Nasr, E, Nilsson, P, Oliveras, A, Ormezzano, O, Paixão-Dias, V, Papadakis, I, Papadopoulos, D, Perl, S, Polónia, J, Pontremoli, R, Pucci, G, Robles, N, Rubin, S, Ruilope, L, Rump, L, Saeed, S, Sanidas, E, Sarzani, R, Schmieder, R, Silhol, F, Sokolovic, S, Solbu, M, Soucek, M, Stergiou, G, Sudano, I, Tabbalat, R, Tengiz, I, Triantafyllidi, H, Tsioufis, K, Václavík, J, van der Giet, M, Van der Niepen, P, Veglio, F, Venzin, R, Viigimaa, M, Weber, T, Widimsky, J, Wuerzner, G, Zelveian, P, Zebekakis, P, Lueders, S, Persu, A, Kreutz, R, Vogt, L, Halimi JM, Sarafidis P, Azizi M, Bilo G, Burkard T, Bursztyn M, Camafort M, Chapman N, Cottone S, de Backer T, Deinum J, Delmotte P, Dorobantu M, Doumas M, Dusing R, Duly-Bouhanick B, Fauvel JP, Fesler P, Gaciong Z, Gkaliagkousi E, Gordin D, Grassi G, Grassos C, Guerrot D, Huart J, Izzo R, Águila FJ, Járai Z, Kahan T, Kantola I, Kociánová E, Limbourg FP, Lopez-Sublet M, Mallamaci F, Manolis A, Marketou M, Mayer G, Mazza A, MacIntyre IM, Mourad JJ, Muiesan ML, Nasr E, Nilsson P, Oliveras A, Ormezzano O, Paixão-Dias V, Papadakis I, Papadopoulos D, Perl S, Polónia J, Pontremoli R, Pucci G, Robles NR, Rubin S, Ruilope LM, Rump LC, Saeed S, Sanidas E, Sarzani R, Schmieder R, Silhol F, Sokolovic S, Solbu M, Soucek M, Stergiou G, Sudano I, Tabbalat R, Tengiz I, Triantafyllidi H, Tsioufis K, Václavík J, van der Giet M, Van der Niepen P, Veglio F, Venzin RM, Viigimaa M, Weber T, Widimsky J, Wuerzner G, Zelveian P, Zebekakis P, Lueders S, Persu A, Kreutz R, Vogt L, Halimi, J, Sarafidis, P, Azizi, M, Bilo, G, Burkard, T, Bursztyn, M, Camafort, M, Chapman, N, Cottone, S, de Backer, T, Deinum, J, Delmotte, P, Dorobantu, M, Doumas, M, Dusing, R, Duly-Bouhanick, B, Fauvel, J, Fesler, P, Gaciong, Z, Gkaliagkousi, E, Gordin, D, Grassi, G, Grassos, C, Guerrot, D, Huart, J, Izzo, R, Águila, F, Járai, Z, Kahan, T, Kantola, I, Kociánová, E, Limbourg, F, Lopez-Sublet, M, Mallamaci, F, Manolis, A, Marketou, M, Mayer, G, Mazza, A, Macintyre, I, Mourad, J, Muiesan, M, Nasr, E, Nilsson, P, Oliveras, A, Ormezzano, O, Paixão-Dias, V, Papadakis, I, Papadopoulos, D, Perl, S, Polónia, J, Pontremoli, R, Pucci, G, Robles, N, Rubin, S, Ruilope, L, Rump, L, Saeed, S, Sanidas, E, Sarzani, R, Schmieder, R, Silhol, F, Sokolovic, S, Solbu, M, Soucek, M, Stergiou, G, Sudano, I, Tabbalat, R, Tengiz, I, Triantafyllidi, H, Tsioufis, K, Václavík, J, van der Giet, M, Van der Niepen, P, Veglio, F, Venzin, R, Viigimaa, M, Weber, T, Widimsky, J, Wuerzner, G, Zelveian, P, Zebekakis, P, Lueders, S, Persu, A, Kreutz, R, Vogt, L, Halimi JM, Sarafidis P, Azizi M, Bilo G, Burkard T, Bursztyn M, Camafort M, Chapman N, Cottone S, de Backer T, Deinum J, Delmotte P, Dorobantu M, Doumas M, Dusing R, Duly-Bouhanick B, Fauvel JP, Fesler P, Gaciong Z, Gkaliagkousi E, Gordin D, Grassi G, Grassos C, Guerrot D, Huart J, Izzo R, Águila FJ, Járai Z, Kahan T, Kantola I, Kociánová E, Limbourg FP, Lopez-Sublet M, Mallamaci F, Manolis A, Marketou M, Mayer G, Mazza A, MacIntyre IM, Mourad JJ, Muiesan ML, Nasr E, Nilsson P, Oliveras A, Ormezzano O, Paixão-Dias V, Papadakis I, Papadopoulos D, Perl S, Polónia J, Pontremoli R, Pucci G, Robles NR, Rubin S, Ruilope LM, Rump LC, Saeed S, Sanidas E, Sarzani R, Schmieder R, Silhol F, Sokolovic S, Solbu M, Soucek M, Stergiou G, Sudano I, Tabbalat R, Tengiz I, Triantafyllidi H, Tsioufis K, Václavík J, van der Giet M, Van der Niepen P, Veglio F, Venzin RM, Viigimaa M, Weber T, Widimsky J, Wuerzner G, Zelveian P, Zebekakis P, Lueders S, Persu A, Kreutz R, and Vogt L
- Abstract
Objective: Real-life management of hypertensive patients with chronic kidney disease (CKD) is unclear. Methods: A survey was conducted in 2023 by the European Society of Hypertension (ESH) to assess management of CKD patients referred to ESH-Hypertension Excellence Centres (ESH-ECs) at first referral visit. The questionnaire contained 64 questions with which ESH-ECs representatives were asked to estimate preexisting CKD management quality. Results: Overall, 88 ESH-ECs from 27 countries participated (fully completed surveys: 66/88 [75.0%]). ESH-ECs reported that 28% (median, interquartile range: 15-50%) had preexisting CKD, with 10% of them (5-30%) previously referred to a nephrologist, while 30% (15-40%) had resistant hypertension. The reported rate of previous recent (<6 months) estimated glomerular filtration rate (eGFR) and urine albumin-creatinine ratio (UACR) testing were 80% (50-95%) and 30% (15-50%), respectively. The reported use of renin-angiotensin system blockers was 80% (70-90%). When a nephrologist was part of the ESH-EC teams the reported rates SGLT2 inhibitors (27.5% [20-40%] vs. 15% [10-25], P = 0.003), GLP1-RA (10% [10-20%] vs. 5% [5-10%], P = 0.003) and mineralocorticoid receptor antagonists (20% [10-30%] vs. 15% [10-20%], P = 0.05) use were greater as compared to ESH-ECs without nephrologist participation. The rate of reported resistant hypertension, recent eGFR and UACR results and management of CKD patients prior to referral varied widely across countries. Conclusions: Our estimation indicates deficits regarding CKD screening, use of nephroprotective drugs and referral to nephrologists before referral to ESH-ECs but results varied widely across countries. This information can be used to build specific programs to improve care in hypertensives with CKD.
- Published
- 2024
6. Short-Term Dietary Intervention with Whole Oats Protects from Antibiotic-Induced Dysbiosis
- Author
-
Stephen K. Costa, Katherine Antosca, Chapman N. Beekman, Rachel L. Peterson, Swathi Penumutchu, and Peter Belenky
- Subjects
antibiotic-induced dysbiosis ,dysbiosis ,gut microbiome ,microbiome ,Microbiology ,QR1-502 - Abstract
ABSTRACT Antibiotic-induced gut microbiome dysbiosis (AID) is known to be influenced by host dietary composition. However, how and when diet modulates gut dysbiosis remains poorly characterized. Thus, here, we utilize a multi-omics approach to characterize how a diet supplemented with oats, a rich source of microbiota-accessible carbohydrates, or dextrose impacts amoxicillin-induced changes to gut microbiome structure and transcriptional activity. We demonstrate that oat administration during amoxicillin challenge provides greater protection from AID than the always oats or recovery oats diet groups. In particular, the group in which oats were provided at the time of antibiotic exposure induced the greatest protection against AID while the other oat diets saw greater effects after amoxicillin challenge. The oat diets likewise reduced amoxicillin-driven elimination of Firmicutes compared to the dextrose diet. Functionally, gut communities fed dextrose were carbohydrate starved and favored respiratory metabolism and consequent metabolic stress management while oat-fed communities shifted their transcriptomic profile and emphasized antibiotic stress management. The metabolic trends were exemplified when assessing transcriptional activity of the following two common gut commensal bacteria: Akkermansia muciniphila and Bacteroides thetaiotaomicron. These findings demonstrate that while host diet is important in shaping how antibiotics effect the gut microbiome composition and function, diet timing may play an even greater role in dietary intervention-based therapeutics. IMPORTANCE We utilize a multi-omics approach to demonstrate that diets supplemented with oats, a rich source of microbiota-accessible carbohydrates, are able to confer protection against antibiotic-induced dysbiosis (AID). Our findings affirm that not only is host diet important in shaping antibiotics effects on gut microbiome composition and function but also that the timing of these diets may play an even greater role in managing AID. This work provides a nuanced perspective on dietary intervention against AID and may be informative on preventing AID during routine antibiotic treatment.
- Published
- 2023
- Full Text
- View/download PDF
7. Content and delivery preferences for information to support the management of high blood pressure
- Author
-
Chapman, N, Marques, FZ, Picone, DS, Adji, A, Broughton, BRS, Dinh, QN, Gabb, G, Lambert, GW, Mihailidou, AS, Nelson, MR, Stowasser, M, Schlaich, M, Schultz, MG, Mynard, JP, Climie, RE, Chapman, N, Marques, FZ, Picone, DS, Adji, A, Broughton, BRS, Dinh, QN, Gabb, G, Lambert, GW, Mihailidou, AS, Nelson, MR, Stowasser, M, Schlaich, M, Schultz, MG, Mynard, JP, and Climie, RE
- Abstract
Blood pressure(BP) management interventions have been shown to be more effective when accompanied by appropriate patient education. As high BP remains poorly controlled, there may be gaps in patient knowledge and education. Therefore, this study aimed to identify specific content and delivery preferences for information to support BP management among Australian adults from the general public. Given that BP management is predominantly undertaken by general practitioners(GPs), information preferences to support BP management were also ascertained from a small sample of Australian GPs. An online survey of adults was conducted to identify areas of concern for BP management to inform content preferences and preferred format for information delivery. A separate online survey was also delivered to GPs to determine preferred information sources to support BP management. Participants were recruited via social media. General public participants (n = 465) were mostly female (68%), >60 years (57%) and 49% were taking BP-lowering medications. The management of BP without medications, and role of lifestyle in BP management were of concern among 30% and 26% of adults respectively. Most adults (73%) preferred to access BP management information from their GP. 57% of GPs (total n = 23) preferred information for supporting BP management to be delivered via one-page summaries. This study identified that Australian adults would prefer more information about the management of BP without medications and via lifestyle delivered by their GP. This could be achieved by providing GPs with one-page summaries on relevant topics to support patient education and ultimately improve BP management.
- Published
- 2024
8. Yampi Peninsula felsic Hart Dolerite: re-evaluating the Nellie Tonalite using evidence from whole rock, petrography and geochronology.
- Author
-
Zivkovic, Z., Orth, K., Chapman, N., Oalmann, J., Baker, M., Cracknell, M. J., and Barker, S.
- Subjects
MINES & mineral resources ,DIABASE ,TONALITE ,MANTLE plumes ,PETROLOGY - Abstract
The Nellie Tonalite forms a discontinuous 20 km elongate northwest-trending felsic intrusion at the far-western end of the Western Zone of the Lamboo Province, in the Wunaamin Miliwundi Orogen, Western Australia. This intrusion is poorly understood with previous interpretations assigning it to the ca 1860 Ma Paperbark Supersuite. We present the first geochronological results for the Nellie Tonalite, which have a weighted mean laser ablation, inductively coupled plasma, mass spectrometry (LA-ICP-MS) U–Pb zircon age of 1794 ± 4 Ma. This date is coincident with the age for felsic granophyres of the Hart Dolerite, which have previously been described from the Kimberley Basin overlying the Halls Creek Orogen and central parts of the Wunaamin Miliwundi Orogen. Other similarities of the Nellie Tonalite with the felsic Hart Dolerite are micrographic and granophyric intergrowths of quartz and K-feldspar, and a distinct geochemical depletion of V. This V depletion is interpreted to be the result of closed-system, in situ fractional crystallisation of titanomagnetite from a basaltic composition. The fractional residue from this process can be found at several locations across the Halls Creek Orogen and Wunaamin Miliwundi Orogen and at Speewah Dome in the east Kimberley where magnetite gabbros within the Hart Dolerite also host a large Ti–V mineral resource. It is proposed that the Nellie Tonalite is a western correlate of the felsic Hart Dolerite. This demonstrates that the magmatic processes required for Speewah-style Ti–V mineralisation are extensive across the entire Lamboo Province. Additionally, the scale, constancy of the composition, texture and age of the felsic Hart Dolerite encompassing the entire inland margin of the Kimberley Region, and the rapid emplacement time of <3 m.y., support the interpretation of a mantle plume model for the emplacement of the Hart Dolerite. KEY POINTS: The Nellie Tonalite is redefined as a granophyric granite, has been dated to 1794 ± 4 Ma and is coeval with the ca 1800 Ma Hart Dolerite. Petrographic, geochemical and geochronological evidence suggests that the Nellie Tonalite is a product of in situ fractional crystallisation of the Hart Dolerite (felsic Hart Dolerite). Plots of Ti/Nb vs V/Sc are ideal in identifying the distinctive V-depletion associated with the felsic Hart Dolerite, which marks a valuable stratigraphic horizon for identifying potential Speewah-style Ti–V mineralisation. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
9. Testing Magnetic Field Models for the Class 0 Protostar L1527
- Author
-
Davidson, J. A., Li, Z. -Y., Hull, C. L. H., Plambeck, R. L., Kwon, W., Crutcher, R. M., Looney, L. W., Novak, G., Chapman, N. L., Matthews, B. C., Stephens, I. W., Tobin, J. J., and Jones, T. J.
- Subjects
Astrophysics - Solar and Stellar Astrophysics - Abstract
For the Class 0 protostar, L1527, we compare 131 polarization vectors from SCUPOL/JCMT, SHARP/CSO and TADPOL/CARMA observations with the corresponding model polarization vectors of four ideal-MHD, non-turbulent, cloud core collapse models. These four models differ by their initial magnetic fields before collapse; two initially have aligned fields (strong and weak) and two initially have orthogonal fields (strong and weak) with respect to the rotation axis of the L1527 core. Only the initial weak orthogonal field model produces the observed circumstellar disk within L1527. This is a characteristic of nearly all ideal-MHD, non-turbulent, core collapse models. In this paper we test whether this weak orthogonal model also has the best agreement between its magnetic field structure and that inferred from the polarimetry observations of L1527. We found that this is not the case; based on the polarimetry observations the most favored model of the four is the weak aligned model. However, this model does not produce a circumstellar disk, so our result implies that a non-turbulent, ideal-MHD global collapse model probably does not represent the core collapse that has occurred in L1527. Our study also illustrates the importance of using polarization vectors covering a large area of a cloud core to determine the initial magnetic field orientation before collapse; the inner core magnetic field structure can be highly altered by a collapse and so measurements from this region alone can give unreliable estimates of the initial field configuration before collapse., Comment: 43 pages, 9 figures, 4 tables. Accepted by the Astrophysical Journal
- Published
- 2014
- Full Text
- View/download PDF
10. Radiation therapy education for rural and remote GPs
- Author
-
Chapman, N A, Oultram, S C, and Jovanovic, K
- Published
- 2008
11. Magnetic Field Structure around Low-Mass Class 0 Protostars: B335, L1527 and IC348-SMM2
- Author
-
Davidson, J. A., Novak, G., Matthews, T. G., Matthews, B., Goldsmith, P. F., Chapman, N., Volgenau, N. H., Vaillancourt, J. E., and Attard, M.
- Subjects
Astrophysics - Astrophysics of Galaxies - Abstract
We report new 350 micron polarization observations of the thermal dust emission from the cores surrounding the low-mass, Class 0 YSOs L1527, IC348-SMM2 and B335. We have inferred magnetic field directions from these observations, and have used them together with results in the literature to determine whether magnetically regulated core-collapse and star-formation models are consistent with the observations. These models predict a pseudo-disk with its symmetry axis aligned with the core magnetic field. The models also predict a magnetic field pinch structure on a scale less than or comparable to the infall radii for these sources. In addition, if the core magnetic field aligns (or nearly aligns) the core rotation axis with the magnetic field before core collapse, then the models predict the alignment (or near alignment) of the overall pinch field structure with the bipolar outflows in these sources. We show that if one includes the distorting effects of bipolar outflows on magnetic fields, then in general the observational results for L1527 and IC348-SMM2 are consistent with these magnetically regulated models. We can say the same for B335 only if we assume the distorting effects of the bipolar outflow on the magnetic fields within the B335 core are much greater than for L1527 and IC348-SMM2. We show that the energy densities of the outflows in all three sources are large enough to distort the magnetic fields predicted by magnetically regulated models., Comment: Accepted for publication in The Astrophysical Journal
- Published
- 2011
- Full Text
- View/download PDF
12. The Spitzer Gould Belt Survey of Large Nearby Interstellar Clouds: Discovery of a Dense Embedded Cluster in the Serpens-Aquila Rift
- Author
-
Gutermuth, R. A., Bourke, T. L., Allen, L. E., Myers, P. C., Megeath, S. T., Matthews, B. C., Jørgensen, J. K., Di Francesco, J., Ward-Thompson, D., Huard, T. L., Brooke, T. Y., Dunham, M. M., Cieza, L. A., Harvey, P. M., and Chapman, N. L.
- Subjects
Astrophysics - Abstract
We report the discovery of a nearby, embedded cluster of young stellar objects, associated filamentary infrared dark cloud, and 4.5 micron shock emission knots from outflows detected in Spitzer/IRAC mid-infrared imaging of the Serpens-Aquila Rift obtained as part of the Spitzer Gould Belt Legacy Survey. We also present radial velocity measurements of the region from molecular line observations obtained with the Submillimeter Array (SMA) that suggest the cluster is co-moving with the Serpens Main embedded cluster 3 degrees to the north. We therefore assign it the same distance, 260 pc. The core of the new cluster, which we call Serpens South, is composed of an unusually large fraction of protostars (77%) at high mean surface density (>430 pc^-2) and short median nearest neighbor spacing (3700 AU). We perform basic cluster structure characterization using nearest neighbor surface density mapping of the YSOs and compare our findings to other known clusters with equivalent analyses available in the literature., Comment: 11 pages, 3 figures; Accepted to ApJ Letters; full resolution version at http://www.cfa.harvard.edu/~rgutermuth/preprints/gutermuth_serps.pdf
- Published
- 2007
- Full Text
- View/download PDF
13. The Spitzer c2d Survey of Large, Nearby, Interstellar Clouds: VI. Perseus Observed with MIPS
- Author
-
Rebull, L. M., Stapelfeldt, K. R., Evans II, N. J., Joergensen, J. K., Harvey, P. M., Brooke, T. Y., Bourke, T. L., Padgett, D. L., Chapman, N. L., Lai, S. -P., Spiesmann, W. J., Noreiga-Crespo, A., Merin, B., Huard, T., Allen, L. E., Blake, G. A., Jarrett, T., Koerner, D. W., Mundy, L. G., Myers, P. C., Sargent, A. I., van Dishoeck, E. F., Wahhaj, Z., and Young, K. E.
- Subjects
Astrophysics - Abstract
We present observations of 10.6 square degrees of the Perseus molecular cloud at 24, 70, and 160 microns with the Spitzer Space Telescope Multiband Imaging Photometer for Spitzer (MIPS). The image mosaics show prominent, complex extended emission dominated by illuminating B stars on the East side of the cloud, and by cold filaments of 160 micron emission on the West side. Of 3950 point sources identified at 24 microns, 1141 have 2MASS counterparts. A quarter of these populate regions of the Ks vs. Ks-[24] diagram that are distinct from stellar photospheres and background galaxies, and thus are likely to be cloud members with infrared excess. Nearly half (46%) of these 24 micron excess sources are distributed outside the IC 348 and NGC 1333 clusters. NGC 1333 shows the highest fraction of stars with flat or rising spectral energy distributions (28%), while Class II SEDs are most common in IC 348. These results are consistent with previous relative age determinations for the two clusters. The intercluster region contains several tightly clumped (r~0.1 pc) young stellar aggregates whose members exhibit a wide variety of infrared spectral energy distributions characteristic of different circumstellar environments. One possible explanation is a significant age spread among the aggregate members, such that some have had time to evolve more than others. Alternatively, if the aggregate members all formed at roughly the same time, then remarkably rapid circumstellar evolution would be required to account for the association of Class I and Class III sources at ages <~1 Myr. We highlight important results for several other objects as well (full abstract in the paper)., Comment: 82 pages, 32 figures, accepted to ApJS; ALL figures (even line drawings) had to be degraded to be accepted by the system here; the full-res figures are available in the version linked from the 'publications' area available at http://peggysue.as.utexas.edu/SIRTF/
- Published
- 2007
- Full Text
- View/download PDF
14. Abundant crystalline silicates in the disk of a very low mass star
- Author
-
Merin, B., Augereau, J. -C., van Dishoeck, E. F., Kessler-Silacci, J., Dullemond, C. P., Blake, G. A., Lahuis, F., Brown, J. M., Geers, V. C., Pontoppidan, K. M., Comeron, F., Frasca, A., Guieu, S., Alcala, J. M., Boogert, A. C. A., Evans II, N. J., D'Alessio, P., Mundy, L. G., and Chapman, N.
- Subjects
Astrophysics - Abstract
We announce the discovery of SST-Lup3-1, a very low mass star close to the brown dwarf boundary in Lupus III with a circum(sub)stellar disk, discovered by the `Cores to Disks' Spitzer Legacy Program from mid-, near-infrared and optical data, with very conspicuous crystalline silicate features in its spectrum. It is the first of such objects with a full 5 to 35 micron spectrum taken with the IRS and it shows strong 10 and 20 micron silicate features with high feature to continuum ratios and clear crystalline features out to 33 micron. The dust in the disk upper layer has a crystalline silicate grain fraction between 15% and 33%, depending on the assumed dust continuum. The availability of the full Spitzer infrared spectrum allows an analysis of the dust composition as a function of temperature and position in the disk. The hot (~ 300 K) dust responsible for the 10 micron feature consists of a roughly equal mix of small (~ 0.1 micron) and large (~ 1.5 micron) grains, whereas the cold (~ 70 K) dust responsible for the longer wavelength silicate features contains primarily large grains (> 1 micron). Since the cold dust emission arises from deeper layers in the inner (< 3 AU) disk as well as from the surface layers of the outer (3-5 AU) disk, this provides direct evidence for combined grain growth and settling in the disk. The inferred crystalline mass fractions in the two components are comparable. Since only the inner 0.02 AU of the disk is warm enough to anneal the amorphous silicate grains, even the lowest fraction of 15% of crystalline material requires either very efficient mixing or other formation mechanisms., Comment: Accepted for publication in ApJ. 19 pages and 4 figures. V2 with correct references
- Published
- 2007
- Full Text
- View/download PDF
15. The Spitzer c2d Survey of Nearby Dense Cores: I: First Direct Detection of the Embedded Source in IRAM 04191+1522
- Author
-
Dunham, M. M., Evans II, N. J., Bourke, T. L., Dullemond, C. P., Young, C. H., Brooke, T. Y., Chapman, N., Myers, P. C., Porras, A., Spiesman, W., Teuben, P. J., and Wahhaj, Z.
- Subjects
Astrophysics - Abstract
We report the first detections of the Class 0 protostellar source IRAM 04191+1522 at wavelengths shortward of 60 microns with the Spitzer Space Telescope. We see extended emission in the Spitzer images that suggests the presence of an outflow cavity in the circumstellar envelope. We combine the Spitzer observations with existing data to form a complete dataset ranging from 3.6 to 1300 microns and use these data to construct radiative transfer models of the source. We conclude that the internal luminosity of IRAM 04191+1522, defined to be the sum of the luminosity from the internal sources (a star and a disk), is L_int = 0.08 +/- 0.04 L_sun, placing it among the lowest luminosity protostars known. Though it was discovered before the launch of the Spitzer Space Telescope, IRAM 04191+1522 falls within a new class of Very Low Luminosity Objects being discovered by Spitzer. Unlike the two other well-studied objects in this class, which are associated either with weak, compact outflows or no outflows at all, IRAM 04191+1522 has a well-defined molecular outflow with properties consistent with those expected based on relations derived from higher luminosity (L_int > 1 L_sun) protostars. We discuss the difficulties in understanding IRAM 04191+1522 in the context of the standard model of star formation, and suggest a possible explanation for the very low luminosity of this source., Comment: Accepted for publication in the Astrophysical Journal. 39 pages, 9 figures. See http://peggysue.as.utexas.edu/SIRTF/ for high-resolution figures
- Published
- 2006
- Full Text
- View/download PDF
16. Weak-line T Tauri Star Disks I. Initial Spitzer Results from the Cores to Disks Legacy Project
- Author
-
Padgett, D. L., Cieza, L., Stapelfeldt, K. R., Evans, N. J., Koerner, D., Sargent, A., Fukagawa, M., van Dishoek, E. F., Augereau, J., Allen, L., Blake, G., Brooke, T., Chapman, N., Harvey, P., Porras, A., Lai, S., Mundy, L., Myers, P. C., Spiesman, W., and Wahhaj, Z.
- Subjects
Astrophysics - Abstract
Using the Spitzer Space Telescope, we have observed 90 weak-line and classical T Tauri stars in the vicinity of the Ophiuchus, Lupus, Chamaeleon, and Taurus star-forming regions as part of the Cores to Disks (c2d) Spitzer Legacy project. In addition to the Spitzer data, we have obtained contemporaneous optical photometry to assist in constructing spectral energy distributions. These objects were specifically chosen as solar-type young stars with low levels of H alpha emission, strong X-ray emission, and lithium absorption i.e. weak-line T Tauri stars, most of which were undetected in the mid-to-far IR by the IRAS survey. Weak-line T Tauri stars are potentially extremely important objects in determining the timescale over which disk evolution may take place. Our objective is to determine whether these young stars are diskless or have remnant disks which are below the detection threshold of previous infrared missions. We find that only 5/83 weak-line T Tauri stars have detectable excess emission between 3.6 and 70 micron which would indicate the presence of dust from the inner few tenths of an AU out to the planet-forming regions a few tens of AU from the star. Of these sources, two have small excesses at 24 microns consistent with optically thin disks; the others have optically thick disks already detected by previous IR surveys. All of the seven classical T Tauri stars show excess emission at 24 and 70 micron, although their properties vary at the shorter wavelengths. Our initial results show that disks are rare among young stars selected for their weak H alpha emission., Comment: 29 pages, 9 figures, accepted for publication in ApJ
- Published
- 2006
17. The Spitzer c2d Survey of Large, Nearby, Interstellar Clouds. I. Chamaeleon II Observed with MIPS
- Author
-
Young, K. E., Harvey, P. M., Brooke, T. Y., Chapman, N., Kauffmann, J., Bertoldi, F., Lai, S. -P., Alcala', J., Bourke, T. L., Spiesman, W., Allen, L. E., Blake, G. A., Evans II, N. J., Koerner, D. W., Mundy, L. G., Myers, P. C., Padgett, D. L., Salinas, A., Sargent, A. I., Stapelfeldt, K. R., Teuben, P., van Dishoeck, E. F., and Wahhaj, Z.
- Subjects
Astrophysics - Abstract
We present maps of over 1.5 square degrees in Chamaeleon (Cha) II at 24, 70, and 160 micron observed with the Spitzer Space Telescope Multiband Imaging Photometer for Spitzer (MIPS) and a 1.2 square degree millimeter map from SIMBA on the Swedish-ESO Submillimetre Telescope (SEST). The c2d Spitzer Legacy Team's data reduction pipeline is described in detail. Over 1500 24 micron sources and 41 70 micron sources were detected by MIPS with fluxes greater than 10-sigma. More than 40 potential YSOs are identified with a MIPS and 2MASS color-color diagram and by their spectral indices, including two previously unknown sources with 24 micron excesses. Our new SIMBA millimeter map of Cha II shows that only a small fraction of the gas is in compact structures with high column densities. The extended emission seen by MIPS is compared with previous CO observations. Some selected interesting sources, including two detected at 1 mm, associated with Cha II are discussed in detail and their SEDs presented. The classification of these sources using MIPS data is found to be consistent with previous studies., Comment: 44 pages, 12 figures (1 color), to be published in ApJ
- Published
- 2005
- Full Text
- View/download PDF
18. A 'Starless' Core that Isn't: Detection of a Source in the L1014 Dense Core with the Spitzer Space Telescope
- Author
-
Young, C. H., Joergensen, J. K., Shirley, Y. L., Kauffmann, J., Huard, T., Lai, S. -P., Lee, C. W., Crapsi, A., Bourke, T. L., Dullemond, C. P., Brooke, T. Y., Porras, A., Spiesman, W., Allen, L. E., Blake, G. A., Evans II, N. J., Harvey, P. M., Koerner, D. W., Mundy, L. G., Myers, P. C., Padgett, D. L., Sargent, A. I., Stapelfeldt, K. R., van Dishoeck, E. F., Bertoldi, F., Chapman, N., Cieza, L., DeVries, C. H., Ridge, N. A., and Wahhaj, Z.
- Subjects
Astrophysics - Abstract
We present observations of L1014, a dense core in the Cygnus region previously thought to be starless, but data from the Spitzer Space Telescope shows the presence of an embedded source. We propose a model for this source that includes a cold core, heated by the interstellar radiation field, and a low-luminosity internal source. The low luminosity of the internal source suggests a substellar object. If L1014 is representative, other "starless" cores may turn out to harbor central sources., Comment: 7 pages, To appear in the ApJS Spitzer Special Edition
- Published
- 2004
- Full Text
- View/download PDF
19. Short-term evolution strategies for host adaptation and drug escape in human fungal pathogens.
- Author
-
Chapman N Beekman and Iuliana V Ene
- Subjects
Immunologic diseases. Allergy ,RC581-607 ,Biology (General) ,QH301-705.5 - Published
- 2020
- Full Text
- View/download PDF
20. Online Resources Addressing Home Blood Pressure Measurement: Do They Align With Current Guideline Recommendations, and are They Readable?
- Author
-
Clapham, E., primary, Picone, D., additional, Carmichael, S., additional, Sharman, J., additional, and Chapman, N., additional
- Published
- 2023
- Full Text
- View/download PDF
21. Inference of Sound Attenuation in Marine Sediments from Modal Dispersion in Shallow Water
- Author
-
Chapman, N. Ross, Zeng, Juan, Zhou, Lisheng, editor, Xu, Wen, editor, Cheng, Qianliu, editor, and Zhao, Hangfang, editor
- Published
- 2016
- Full Text
- View/download PDF
22. Replication of a rare risk haplotype on 1p36.33 for autism spectrum disorder
- Author
-
Chapman, N. H., Bernier, R. A., Webb, S. J., Munson, J., Blue, E. M., Chen, D.-H., Heigham, E., Raskind, W. H., and Wijsman, Ellen M.
- Published
- 2018
- Full Text
- View/download PDF
23. Development and evaluation of an online surgical elective for medical students
- Author
-
Goble, M and Chapman, N
- Subjects
General Medicine ,Education - Abstract
Background Decreased experiential learning opportunities exacerbated by the COVID-19 pandemic have increased development of online surgical educational courses. To what extent may such courses provide exposure to broad and accessible surgical education? Methods Surge is a 6-week online surgical elective hosted within a virtual learning environment, covering all surgical specialties. Course content is mapped to the Royal College of Surgeons’ Undergraduate Curriculum in Surgery. Each week consultant surgeons discuss their specialty in short videos on anatomy, pathology and lifestyle of a surgeon. Students also engage with learning activities; further reading lists; formative quizzes and live sessions including suturing practice. Participants were medical students undertaking third-year electives at the University of Sheffield. Pre- and post-course questionnaires investigated student interest in surgery, understanding of steps required to pursue a surgical career and confidence in surgical environments. Qualitative data was collected via free-text responses and analysed with content analysis. Quantitative data was collected using 5-point Likert scales (1 = Strongly Disagree; 5 = Strongly Agree) and analysed using the Wilcoxon signed-rank test. Results Twenty-two students participated in Surge over five 6-week cohorts. Examination of free-text responses revealed students gained increased understanding of available surgical career options. Students felt better informed regarding different surgical specialties (median score 2.5 vs. 4, p = 0.000) and steps required to develop a surgical portfolio (median score 2 vs. 5, p = 0.000). Additionally, confidence in understanding of relevant intraoperative steps improved (median score 3 vs. 4, p = 0.000). Conclusion These data demonstrate Surge increased student confidence and understanding of surgical careers despite reduced in-person opportunities to engage with surgical education. Surge will continue to be developed and evaluated on a larger scale.
- Published
- 2023
24. Inversion of geoacoustic model parameters using ship radiated noise
- Author
-
Chapman, N. Ross, Dizaji, Reza M., Kirlin, R. Lynn, Caiti, Andrea, editor, Chapman, N. Ross, editor, Hermand, Jean-Pierre, editor, and Jesus, Sérgio M., editor
- Published
- 2006
- Full Text
- View/download PDF
25. DNA methylation of Kr-h1 is involved in regulating ovary activation in worker honeybees (Apis mellifera)
- Author
-
Kilaso, M., Remnant, E. J., Chapman, N. C., Oldroyd, B. P., and Chanchao, C.
- Published
- 2017
- Full Text
- View/download PDF
26. The effect of TRV027 on coagulation in COVID 19: A pilot randomized, placebo-controlled controlled trial
- Author
-
Robbins, AJ, Che Bakri, NA, Toke-Bjolgerud, E, Edwards, A, Vikraman, A, Michalsky, C, Fossler, M, Lemm, N-M, Medhipour, S, Budd, W, Gravani, A, Hurley, L, Kapil, V, Jackson, A, Lonsdale, D, Latham, V, Laffan, M, Chapman, N, Cooper, N, Szydlo, R, Boyle, J, Pollock, KM, and Owen, D
- Abstract
COVID-19 causes significant thrombosis and coagulopathy, with elevated D-dimer a predictor of adverse outcome. The precise mechanism of this coagulopathy remains unclear, one hypothesis is that loss of Angiotensin Converting Enzyme 2 activity during viral endocytosis leads to pro-inflammatory angiotensin II accumulation, loss of angiotensin-1-7 and subsequent vascular endothelial activation. We undertook a double blind randomised, placebo controlled experimental medicine study to assess the effect of TRV027, a synthetic angiotensin-1-7 analogue on D-dimer in 30 patients admitted to hospital with COVID-19 (REC ref. 20/HRA/3414), Clinical Trial No. NCT04419610. The study showed a similar rate of adverse events in TRV027 and control groups. There was a numerical decrease in D-dimer in the TRV027 group and increase in D-dimer in the placebo group, however, this did not reach statistical significance (p=0.15). A Bayesian analysis demonstrated there was a 92% probability that this change represented a true drug effect.
- Published
- 2022
27. TR-MIMO detection of a small target in a shallow water waveguide environment
- Author
-
Pan, Xiang, Hui, Shu, Wen, Xu, and Ross Chapman, N.
- Published
- 2014
- Full Text
- View/download PDF
28. Persistent Coxsackievirus Infection: Enterovirus Persistence in Chronic Myocarditis and Dilated Cardiomyopathy
- Author
-
Chapman, N. M., Kim, K. -S., Compans, Richard W., editor, Cooper, Max D., editor, Honjo, Tasuku, editor, Koprowski, Hilary, editor, Melchers, Fritz, editor, Oldstone, Michael B. A., editor, Olsnes, Sjur, editor, Vogt, Peter K., editor, Tracy, Steven, editor, Oberste, M. Steven, editor, and Drescher, Kristen M., editor
- Published
- 2008
- Full Text
- View/download PDF
29. Inverse Problems in Underwater Acoustics
- Author
-
Chapman, N. Ross, Havelock, David, editor, Kuwano, Sonoko, editor, and Vorländer, Michael, editor
- Published
- 2008
- Full Text
- View/download PDF
30. Evolution of Virulence in Picornaviruses
- Author
-
Tracy, S., Chapman, N. M., Drescher, K. M., Kono, K., Tapprich, W., Compans, R.W., editor, Cooper, M.D., editor, Honjo, T., editor, Koprowski, H., editor, Melchers, F., editor, Oldstone, M.B.A., editor, Olsnes, S., editor, Potter, M., editor, Vogt, P.K., editor, Wagner, H., editor, and Domingo, Esteban, editor
- Published
- 2006
- Full Text
- View/download PDF
31. Managing Australian Radioactive Waste in an International Environment
- Author
-
Pacific Basin Nuclear Conference (15th : 2006 : Sydney, Australia), Kurzeme, M, McCombie, C, and Chapman, N
- Published
- 2006
32. The genetic consequences of the anthropogenic movement of social bees
- Author
-
Byatt, M. A., Chapman, N. C., Latty, T., and Oldroyd, B. P.
- Published
- 2016
- Full Text
- View/download PDF
33. Content and delivery preferences for information to support the management of high blood pressure
- Author
-
Chapman, N., primary, Marques, F. Z., additional, Picone, D. S., additional, Adji, A., additional, Broughton, B. R. S., additional, Dinh, Q. N., additional, Gabb, G., additional, Lambert, G. W., additional, Mihailidou, A. S., additional, Nelson, M. R., additional, Stowasser, M., additional, Schlaich, M., additional, Schultz, M. G., additional, Mynard, J. P., additional, and Climie, R. E., additional
- Published
- 2022
- Full Text
- View/download PDF
34. Haplotype Blocks in Small Populations
- Author
-
Thompson, E. A., Chapman, N. H., Goos, Gerhard, editor, Hartmanis, Juris, editor, van Leeuwen, Jan, editor, Istrail, Sorin, editor, Pevzner, Pavel, editor, Waterman, Michael, editor, and Clark, Andrew, editor
- Published
- 2004
- Full Text
- View/download PDF
35. Observing the fluctuations of arrival time and amplitude with short-range experimental data
- Author
-
Duan, Rui, Yang, Kun De, Chapman, N. Ross, and Ma, Yuan Liang
- Published
- 2013
- Full Text
- View/download PDF
36. The Group B Coxsackieviruses as Vaccines and Vectors
- Author
-
Chapman, N. M., Kim, K.-S., Tracy, S., and Matsumori, Akira, editor
- Published
- 2003
- Full Text
- View/download PDF
37. Cascadia Margin, Northeast Pacific Ocean: Hydrate Distribution from Geophysical Investigations
- Author
-
Spence, G. D., Hyndman, R. D., Chapman, N. R., Riedel, M., Edwards, N., Yuan, J., Haq, Bilal U., editor, and Max, Michael D., editor
- Published
- 2003
- Full Text
- View/download PDF
38. National Survey of Rapid Access Chest Pain Clinics in Australia
- Author
-
Cho, K., Kozor, R., Thiagalingam, A., Biasi, A., Lennox-Bradley, W., Mooney, J., Indraratna, P., Pitney, M., Chetty, R., Ihdayhid, A., Hamilton-Craig, C., French, J., Favretti, J., Thomas, A., Davies, A., Black, A., Zoumberis, C., Al-Fiadh, A., Lowe, H., Kwan, T., Leow, K., Scott, P., Kangaharan, N., Baumann, A., Spiro, J., Kalathil, S., Evans, G., Van, Gaal W., Filipopoulos, B., Chapman, N., Reid, C., Figtree, G., Hillis, G., Jennings, G., and Chow, C.
- Published
- 2024
- Full Text
- View/download PDF
39. Benchmarking Geoacoustic Inversion Methods for Range Dependent Waveguides
- Author
-
Chapman, N. Ross, Chin-Bing, S., King, D., Evans, R. B., Pace, Nicholas G., editor, and Jensen, Finn B., editor
- Published
- 2002
- Full Text
- View/download PDF
40. The corona-virus disease 2019 pandemic compromised routine care for hypertension: a survey conducted among excellence centers of the European Society of Hypertension
- Author
-
Weber, T, Januszewicz, A, Rosei, Ea, Tsioufis, K, Okorie, M, Stergiou, Gs, Volpe, M, Kreutz, R, Abraham, G, Azizi, M, Barna, I, Barroso, Wks, Brguljan, J, Chapman, N, De Backer, T, Dorobantu, M, Eckert, S, Gaciong, Z, Giannattasio, C, Glover, M, Gottsater, A, Grassos, C, Jarai, Z, Aguila, Fj, Kahan, T, Lopez-Sublet, M, Lovic, D, Lurbe, E, Makris, Tk, Mallamaci, F, Manolis, Aj, Marketou, M, Mazza, A, Mediavilla, Jd, Muiesan, Ml, Muxfeldt, Es, Nasr, E, Papadakis, I, Parounak, Z, Obregon, S, Oliveras, A, Pontremoli, R, Raev, D, Rajkumar, C, Redon, J, Robles, Nr, Rump, Lc, Sarzani, R, Sierra, C, Sirenko, Y, Stojanov, V, Tikkanen, I, Vaclavik, J, Veglio, F, Viigimaa, M, Webb, D, Zebekakis, P, and Zweiker, R
- Subjects
medicine.medical_specialty ,Ambulatory blood pressure ,Coronavirus disease 2019 (COVID-19) ,Physiology ,media_common.quotation_subject ,Shutdown ,Angiotensin-Converting Enzyme Inhibitors ,Covid-19 ,blood pressure ,hypertension routine care ,renin-angiotensin system inhibitors ,Angiotensin Receptor Antagonists ,Antihypertensive Agents ,Blood Pressure Monitoring, Ambulatory ,COVID-19 ,Delivery of Health Care ,Europe ,Humans ,Hypertension ,Renin-Angiotensin System ,SARS-CoV-2 ,Surveys and Questionnaires ,Health Facilities ,Health Services Accessibility ,Pandemics ,Virus diseases ,Blood Pressure Monitoring ,Excellence ,Ambulatory ,Pandemic ,Internal Medicine ,Medicine ,Routine care ,media_common ,business.industry ,Blood pressure ,Emergency medicine ,angiotensin receptor antagonists ,angiotensin-converting enzyme inhibitors ,antihypertensive agents ,blood pressure monitoring ,ambulatory ,delivery of health care ,humans ,hypertension ,renin-angiotensin system ,surveys and questionnaires ,health facilities ,health services accessibility ,pandemics ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background: The Covid-19 pandemic caused a shutdown of healthcare systems in many countries. We explored the impact on hypertension care in the Excellence Center (EC) network of the European Society of Hypertension. Methods: We conducted a 17-question electronic survey among ECs. Results: Overall, 52 ECs from 20 European and three non-European countries participated, providing hypertension service for a median of 1500 hypertensive patients per center per year. Eighty-five percent of the ECs reported a shutdown lasting for 9 weeks (range 0–16). The number of patients treated per week decreased by 90%: from a median of 50 (range 10–400) before the pandemic to a median of 5.0 (range 0–150) during the pandemic (P < 0.0001). 60% of patients (range 0–100%) declared limited access to medical consultations. The majority of ECs (57%) could not provide 24-h ambulatory BP monitoring, whereas a median of 63% (range 0–100%) of the patients were regularly performing home BP monitoring. In the majority (75%) of the ECs, hypertension service returned to normal after the first wave of the pandemic. In 66% of the ECs, the physicians received many questions regarding the use of renin–angiotensin system (RAS) blockers. Stopping RAS-blocker therapy (in a few patients) either by patients or physicians was reported in 27 and 36.5% of the ECs. Conclusion: Patient care in hypertension ECs was compromised during the Covid-19-related shutdown. These data highlight the necessity to develop new strategies for hypertension care including virtual clinics to maintain services during challenging times.
- Published
- 2021
41. Freeze Bath Inversion for Estimation of Geoacoustic Parameters
- Author
-
Chapman, N. Ross, Jaschke, Lothar, Taroudakis, Michael I., editor, and Makrakis, George N., editor
- Published
- 2001
- Full Text
- View/download PDF
42. Barkley Canyon Gas Hydrates: A Synthesis Based on Two Decades of Seafloor Observation and Remote Sensing
- Author
-
Riedel, Michael, Scherwath, Martin, Römer, M., Paull, C. K., Lundsten, E. M., Caress, D., Brewer, P. G., Pohlman, J. W., Lapham, L. L., Chapman, N. R., Whiticar, M. J., Spence, G. D., Enkin, R. J., and Douglas, K.
- Subjects
General Earth and Planetary Sciences - Abstract
Barkley Canyon is one of the few known sites worldwide with the occurrence of thermogenic gas seepage and formation of structure-II and structure-H gas hydrate mounds on the seafloor. This site is the location of continuous seafloor monitoring as part of the Ocean Networks Canada (ONC) cabled observatory off the west coast off Vancouver Island, British Columbia, Canada. We combine repeat remotely operated vehicle (ROV) seafloor video observations, mapping with an autonomous underwater vehicle (AUV), ship-, ROV-, and AUV-based identification of gas flares, as well as seismic and Chirp data to investigate the distribution of fluid migration pathways. Geologically, the site with the prominent gas hydrate mounds and associated fluid seepage is covering an area of ∼0.15 km2 and is situated on a remnant of a rotated fault block that had slipped off the steep flanks of the north-east facing canyon wall. The gas hydrate mounds, nearly constant in dimension over the entire observation period, are associated with gas and oil seepage and surrounded by debris of chemosynthetic communities and authigenic carbonate. The formation of gas hydrate at and near the seafloor requires additional accommodation space created by forming blisters at the seafloor that displace the regular sediments. An additional zone located centrally on the rotated fault block with more diffuse seepage (∼0.02 km2 in extent) has been identified with no visible mounds, but with bacterial mats, small carbonate concretions, and clam beds. Gas venting is seen acoustically in the water column up to a depth of ∼300 m. However, acoustic water-column imaging during coring and ROV dives showed rising gas bubbles to much shallower depth, even
- Published
- 2022
43. Developing a two-way learning monitoring program for Mankarr (Greater Bilby) in the Western Desert, Western Australia
- Author
-
Skroblin, A, Carboon, T, Bidu, G, Taylor, M, Bidu, N, Taylor, W, Taylor, K, Miller, M, Robinson, L, Williams, C, Chapman, N, Marney, M, Marney, C, Biljabu, J, Biljabu, L, Jeffries, P, Samson, H, Charles, P, Game, ET, Wintle, B, Skroblin, A, Carboon, T, Bidu, G, Taylor, M, Bidu, N, Taylor, W, Taylor, K, Miller, M, Robinson, L, Williams, C, Chapman, N, Marney, M, Marney, C, Biljabu, J, Biljabu, L, Jeffries, P, Samson, H, Charles, P, Game, ET, and Wintle, B
- Abstract
Summary Indigenous people are the custodians of knowledge systems that hold detailed awareness of the environment, including applications for monitoring and management to improve biodiversity and cultural outcomes. Indigenous communities are increasingly participating in programs to monitor populations of wildlife. There is a need for frameworks to guide how Indigenous priorities, aspirations and culture can be respected within monitoring programs, as well as case studies that demonstrate how Indigenous knowledge and practice can provide opportunities together with Western science practice to improve the rigour and outcomes of wildlife monitoring. Here, we describe the process of developing a monitoring program that was tailored to be carried out by Kanyirninpa Jukurrpa Indigenous ranger teams to assess the status, trend and response to the management of a threatened and culturally significant species Mankarr (Greater Bilby; Macrotis lagotis). We applied a collaborative two‐way approach, using iterative consultations, elicitations and field trials involving Indigenous and non‐Indigenous project partners to define monitoring objectives, record biocultural knowledge and tailor a sampling methodology to fit the requirements of Martu Traditional Owners. Our project focused on creating a method that would be engaging, accessible and useful for rangers who would carry out the program, and prioritized collection of relevant data for community decision‐making regarding management. We outline our key learnings for co‐design of wildlife monitoring programs on Indigenous lands. Our approach provides insights that will assist in designing other cross‐cultural or participatory monitoring programs.
- Published
- 2022
44. A roadmap of strategies to support cardiovascular researchers: from policy to practice.
- Author
-
Chapman, N, Thomas, EE, Tan, JTM, Inglis, SC, Wu, JHY, Climie, RE, Picone, DS, Blekkenhorst, LC, Wise, SG, Mirabito Colafella, KM, Calkin, AC, Marques, FZ, Chapman, N, Thomas, EE, Tan, JTM, Inglis, SC, Wu, JHY, Climie, RE, Picone, DS, Blekkenhorst, LC, Wise, SG, Mirabito Colafella, KM, Calkin, AC, and Marques, FZ
- Abstract
Cardiovascular disease remains the leading cause of death worldwide. Cardiovascular research has therefore never been more crucial. Cardiovascular researchers must be provided with a research environment that enables them to perform at their highest level, maximizing their opportunities to work effectively with key stakeholders to address this global issue. At present, cardiovascular researchers face a range of challenges and barriers, including a decline in funding, job insecurity and a lack of diversity at senior leadership levels. Indeed, many cardiovascular researchers, particularly women, have considered leaving the sector, highlighting a crucial need to develop strategies to support and retain researchers working in the cardiovascular field. In this Roadmap article, we present solutions to problems relevant to cardiovascular researchers worldwide that are broadly classified across three key areas: capacity building, research funding and fostering diversity and equity. This Roadmap provides opportunities for research institutions, as well as governments and funding bodies, to implement changes from policy to practice, to address the most important factors restricting the career progression of cardiovascular researchers.
- Published
- 2022
45. The Haro Strait Geoacoustic Tomography Experiment
- Author
-
Chapman, N. R., Jaschke, L., Kennedy, A. D., Caiti, A., editor, Hermand, J.-P., editor, Jesus, S. M., editor, and Porter, M. B., editor
- Published
- 2000
- Full Text
- View/download PDF
46. Assessing patterns of admixture and ancestry in Canadian honey bees
- Author
-
Harpur, B. A., Chapman, N. C., Krimus, L., Maciukiewicz, P., Sandhu, V., Sood, K., Lim, J., Rinderer, T. E., Allsopp, M. H., Oldroyd, B. P., and Zayed, A.
- Published
- 2015
- Full Text
- View/download PDF
47. Virus Infection in Cardiomyopathies: Brief Overview, Recent Advances
- Author
-
Tracy, S., Chapman, N. M., Camerini, Fulvio, editor, Gavazzi, Antonello, editor, and De Maria, Renata, editor
- Published
- 1998
- Full Text
- View/download PDF
48. Theory of reflection in learning for radiation therapists
- Author
-
Warren-Forward, HM, Dempsey, SE, and Chapman, N
- Published
- 2008
49. Genetics of Coxsackievirus Virulence
- Author
-
Chapman, N. M., Ramsingh, A. I., Tracy, S., Compans, R. W., editor, Cooper, M., editor, Hogle, J. M., editor, Koprowski, H., editor, Ito, Y., editor, Melchers, F., editor, Oldstone, M., editor, Olsnes, S., editor, Potter, M., editor, Saedler, H., editor, Vogt, P. K., editor, Wagner, H., editor, Tracy, Steven, editor, Chapman, Nora M., editor, and Mahy, Brian W. J., editor
- Published
- 1997
- Full Text
- View/download PDF
50. Coxsackievirus Genetics and the Cardiovirulent Viral Phenotype
- Author
-
Chapman, N., Tracy, S., Ramsingh, A., Romero, J., Curry, K., Shapiro, B., Barry, W., Chin, T., Hufnagel, G., Schultheiss, Heinz-Peter, editor, and Schwimmbeck, Peter, editor
- Published
- 1997
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.