Author: "Chang A.R." - Searchworks@Jio Institute Digital Library Search Results

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31 results on '"Chang A.R."'

1. Major cardiovascular events and subsequent risk of kidney failure with replacement therapy: a CKD Prognosis Consortium study

Author: Mark, P.B., Carrero, J.J., Matsushita, K., Sang, Y., Ballew, S.H., Grams, M.E., Coresh, J., Surapaneni, A., Brunskill, N.J., Chalmers, J., Chan, L., Chang, A.R., Chinnadurai, R., Chodick, G., Cirillo, M., Zeeuw, D. de, Evans, M., Garg, A.X., Gutierrez, O.M., Heerspink, H.J.L., Heine, G.H., Herrington, W.G., Ishigami, J., Kronenberg, F., Lee, J.Y., Levin, A., Major, R.W., Marks, A., Nadkarni, G.N., Naimark, D.M.J., Nowak, C., Rahman, M., Sabanayagam, C., Sarnak, M., Sawhney, S., Schneider, M.P., Shalev, V., Shin, J.I., Siddiqui, M.K., Stempniewicz, N., Sumida, K., Valdivielso, J.M., Brand, J. van den, Yee-Moon Wang, A, Wheeler, D.C., Zhang, L., Visseren, F.L.J., Stengel, B., Mark, P.B., Carrero, J.J., Matsushita, K., Sang, Y., Ballew, S.H., Grams, M.E., Coresh, J., Surapaneni, A., Brunskill, N.J., Chalmers, J., Chan, L., Chang, A.R., Chinnadurai, R., Chodick, G., Cirillo, M., Zeeuw, D. de, Evans, M., Garg, A.X., Gutierrez, O.M., Heerspink, H.J.L., Heine, G.H., Herrington, W.G., Ishigami, J., Kronenberg, F., Lee, J.Y., Levin, A., Major, R.W., Marks, A., Nadkarni, G.N., Naimark, D.M.J., Nowak, C., Rahman, M., Sabanayagam, C., Sarnak, M., Sawhney, S., Schneider, M.P., Shalev, V., Shin, J.I., Siddiqui, M.K., Stempniewicz, N., Sumida, K., Valdivielso, J.M., Brand, J. van den, Yee-Moon Wang, A, Wheeler, D.C., Zhang, L., Visseren, F.L.J., and Stengel, B.
Abstract: Item does not contain fulltext, AIMS: Chronic kidney disease (CKD) increases risk of cardiovascular disease (CVD). Less is known about how CVD associates with future risk of kidney failure with replacement therapy (KFRT). METHODS AND RESULTS: The study included 25 903 761 individuals from the CKD Prognosis Consortium with known baseline estimated glomerular filtration rate (eGFR) and evaluated the impact of prevalent and incident coronary heart disease (CHD), stroke, heart failure (HF), and atrial fibrillation (AF) events as time-varying exposures on KFRT outcomes. Mean age was 53 (standard deviation 17) years and mean eGFR was 89 mL/min/1.73 m2, 15% had diabetes and 8.4% had urinary albumin-to-creatinine ratio (ACR) available (median 13 mg/g); 9.5% had prevalent CHD, 3.2% prior stroke, 3.3% HF, and 4.4% prior AF. During follow-up, there were 269 142 CHD, 311 021 stroke, 712 556 HF, and 605 596 AF incident events and 101 044 (0.4%) patients experienced KFRT. Both prevalent and incident CVD were associated with subsequent KFRT with adjusted hazard ratios (HRs) of 3.1 [95% confidence interval (CI): 2.9-3.3], 2.0 (1.9-2.1), 4.5 (4.2-4.9), 2.8 (2.7-3.1) after incident CHD, stroke, HF and AF, respectively. HRs were highest in first 3 months post-CVD incidence declining to baseline after 3 years. Incident HF hospitalizations showed the strongest association with KFRT [HR 46 (95% CI: 43-50) within 3 months] after adjustment for other CVD subtype incidence. CONCLUSION: Incident CVD events strongly and independently associate with future KFRT risk, most notably after HF, then CHD, stroke, and AF. Optimal strategies for addressing the dramatic risk of KFRT following CVD events are needed.
Published: 2023

2. Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019

Author: Abbafati, C., Machado, D.B., Cislaghi, B., Salman, O.M., Karanikolos, M., McKee, M., Abbas, K.M., Brady, O.J., Larson, H.J., Trias-Llimós, S., Cummins, S., Langan, S.M., Sartorius, B., Hafiz, A., Jenabi, E., Mohammad Gholi Mezerji, N., Borzouei, S., Azarian, G., Khazaei, S., Abbasi, M., Asghari, B., Masoumi, S., Komaki, H., Taherkhani, A., Adabi, M., Abbasifard, M., Bazmandegan, G., Kamiab, Z., Vakilian, A., Anjomshoa, M., Mokari, A., Sabour, S., Shahbaz, M., Saeedi, R., Ahmadieh, H., Yousefinezhadi, T., Haj-Mirzaian, A., Nikbakhsh, R., Safi, S., Asgari, S., Irvani, S.N., Jahanmehr, N., Ramezanzadeh, K., Abbasi-Kangevari, M., Khayamzadeh, M., Abbastabar, H., Shirkoohi, R., Fazlzadeh, M., Janjani, H., Hosseini, M., Mansournia, M., Tohidinik, H., Bakhtiari, A., Fazaeli, A., Mousavi, S., Hasanzadeh, A., Nabavizadeh, B., Malekzadeh, R., Hashemian, M., Pourshams, A., Salimzadeh, H., Sepanlou, S.G., Afarideh, M., Esteghamati, A., Esteghamati, S., Ghajar, A., Heidari, B., Rezaei, N., Mohamadi, E., Rahimi-Movaghar, A., Rahim, F., Eskandarieh, S., Sahraian, M., Mohebi, F., Aminorroaya, A., Ebrahimi, H., Farzadfar, F., Mohajer, B., Pishgar, F., Saeedi Moghaddam, S., Shabani, M., Zarafshan, H., Abolhassani, H., Hafezi-Nejad, N., Heidari-Soureshjani, R., Abdollahi, M., Farahmand, M., Salamati, P., Mehrabi Nasab, E., Tajdini, M., Aghamir, S., Mirzaei, R., Dibaji Forooshani, Z., Khater, M.M., Abd-Allah, F., Abdelalim, A., Abualhasan, A., El-Jaafary, S.I., Hassan, A., Elsharkawy, A., Khater, A.M., Elhabashy, H.R., Salem, M.R.R., Salem, H., Sadeghi, M., Jafarinia, M., Amini-Rarani, M., Mohammadifard, N., Sarrafzadegan, N., Abdollahpour, I., Sarveazad, A., Tehrani-Banihashemi, A., Yoosefi Lebni, J., Manafi, N., Pazoki Toroudi, H., Dorostkar, F., Alipour, V., Sheikhtaheri, A., Arabloo, J., Azari, S., Ghashghaee, A., Rezapour, A., Naserbakht, M., Kabir, A., Mehri, F., Yousefifard, M., Asadi-Aliabadi, M., Babaee, E., Eshrati, B., Goharinezhad, S., Moradi-Lakeh, M., Abedi, P., Rashedi, V., Kumar, V., Elgendy, I.Y., Basu, S., Park, J., Pereira, A., Norheim, O.F., Eagan, A.W., Cahill, L.E., Sheikh, A., Abushouk, A.I., Kraemer, M.U.G., Thakur, B., Bärnighausen, T.W., Shrime, M.G., Abedi, A., Doshi, C.P., Abegaz, K.H., Geberemariyam, B.S., Aynalem, Y.A., Shiferaw, W.S., Abosetugn, A.E., Aboyans, V., Abrams, E.M., Gitimoghaddam, M., Kissoon, N., Stubbs, J.L., Brauer, M., Iyamu, I.O., Kopec, J.A., Pourmalek, F., Ribeiro, A.P., Malta, D.C., Gomez, R.S., Abreu, L.G., Abrigo, M.R.M., Almulhim, A.M., Dahlawi, S.M.A., Pottoo, F.H., Menezes, R.G., Alanzi, T.M., Alumran, A.K., Abu Haimed, A.K., Madadin, M., Alanezi, F.M., Abu-Gharbieh, E., Saddik, B., Abu-Raddad, L.J., Samy, A.M., El Nahas, N., Shalash, A.S., Nabhan, A.F., Kamath, A.M., Kassebaum, N.J., Aravkin, A.Y., Kochhar, S., Sorensen, R.J.D., Afshin, A., Burkart, K., Cromwell, E.A., Dandona, L., Dharmaratne, S.D., Gakidou, E., Hay, S.I., Kyu, H.H., Lopez, A.D., Lozano, R., Misganaw, A.T., Mokdad, A.H., Naghavi, M., Pigott, D.M., Reiner Jr, R.C., Roth, G.A., Stanaway, J.D., Vollset, S., Vos, T., Wang, H., Lim, S.S., Murray, C.J.L., Kalani, R., Ikuta, K.S., Cho, D.Y., Kneib, C.J., Crowe, C.S., Massenburg, B.B., Morrison, S.D., Acebedo, A., Adelson, J.D., Agesa, K.M., Alam, T., Albertson, S.B., Anderson, J.A., Antony, C.M., Ashbaugh, C., Assmus, M., Azhar, G., Balassyano, S., Bannick, M.S., Barthelemy, C.M., Bender, R.G., Bennitt, F.B., Bertolacci, G.J., Biehl, M.H., Bisignano, C., Boon-Dooley, A.S., Briant, P.S., Bryazka, D., Bumgarner, B.R., Callender, C.S., Cao, J., Castle, C.D., Castro, E., Causey, K., Cercy, K.M., Chalek, J., Charlson, F.J., Cohen, A.J., Comfort, H., Compton, K., Croneberger, A.J., Cruz, J.A., Cunningham, M., Dandona, R., Dangel, W.J., Dean, F.E., DeCleene, N.K., Deen, A., Degenhardt, L., Dingels, Z.V., Dippenaar, I.N., Dirac, M.A., Dolgert, A.J., Emmons-Bell, S., Estep, K., Farag, T., Feigin, V.L., Feldman, R., Ferrara, G., Ferrari, A.J., Fitzgerald, R., Force, L.M., Fox, J.T., Frank, T.D., Fu, W., Fukutaki, K., Fuller, J.E., Fullman, N., Galles, N.C., Gardner, W.M., Gershberg Hayoon, A., Goren, E., Gorman, T.M., Gottlich, H.C., Guo, G., Haddock, B., Hagins, H., Haile, L.M., Hamilton, E.B., Han, C., Han, H., Harvey, J.D., Henny, K., Henrikson, H.J., Henry, N.J., Herbert, M.E., Hsiao, T., Huynh, C.K., Iannucci, V.C., Ippolito, H., Irvine, C.M.S., Jafari, H., Jahagirdar, D., James, S.L., Johnson, C.O., Johnson, S.C., Keller, C., Kemmer, L., Kendrick, P.J., Knight, M., Kocarnik, J.M., Krohn, K.J., Larson, S.L., Lau, K.M., Ledesma, J.R., Leever, A.T., LeGrand, K.E., Lescinsky, H., Lin, C., Liu, H., Liu, Z., Lo, J., Lu, A., Ma, J., Maddison, E.R., Manguerra, H., Marks, A., Martopullo, I., Mastrogiacomo, C.I., May, E.A., Mooney, M.D., Mosser, J.F., Mullany, E.C., Mumford, J., Munro, S.B., Nandakumar, V., Nguyen, J., Nguyen, M., Nichols, E., Nixon, M.R., Odell, C.M., Ong, K.L., Orji, A.U., Ostroff, S.M., Pasovic, M., Paulson, K.R., Pease, S.A., Pennini, A., Pierce, M., Pilz, T.M., Pletcher, M., Rao, P.C., Razo, C., Redford, S.B., Reinig, N., Reitsma, M.B., Rhinehart, P., Robalik, T., Roberts, S., Roberts, N.L.S., Rolfe, S., Sbarra, A.N., Schaeffer, L.E., Shackelford, K.A., Shadid, J., Sharara, F., Shaw, D.H., Sheena, B.S., Simpson, K.E., Smith, A., Spencer, C.N., Spurlock, E.E., Stark, B.A., Steiner, C., Steuben, K.M., Sylte, D.O., Tang, M., Taylor, H.J., Terrason, S., Thomson, A.M., Torre, A.E., Travillian, R., Troeger, C.E., Vongpradith, A., Walters, M.K., Wang, J., Watson, A., Watson, S., Whisnant, J.L., Whiteford, H.A., Wiens, K.E., Wilner, L.B., Wilson, S., Wool, E.E., Wozniak, S.S., Wu, J., Wulf Hanson, S., Wunrow, H., Xu, R., Yadgir, S., Yearwood, J.A., York, H.W., Yuan, C., Zhao, J.T., Zheng, P., Zimsen, S.R.M., Zlavog, B.S., Chang, A.Y., Oren, E., Buchbinder, R., Chin, K.L., Guo, Y., Polkinghorne, K.R., Thrift, A.G., Lee, S.W.H., Ackerman, I.N., Cicuttini, F.M., Li, S., Zaman, S., Suleria, H., Zhang, J., Cowie, B.C., Wijeratne, T., Patton, G.C., Sawyer, S.M., Adair, T., Meretoja, A., Adetokunboh, O.O., Adamu, A.A., Iwu, C.J., Parry, C.D.H., Seedat, S., Ndwandwe, D.E., Mahasha, P.W., Stein, D.J., Nnaji, C.A., Sambala, E.Z., Wiysonge, C.S., Adebayo, O.M., Ilesanmi, O.S., Owolabi, M.O., Adeoye, A.M., Adedeji, I.A., Adekanmbi, V., Ibitoye, S.E., John-Akinola, Y.O., Oluwasanu, M.M., Oghenetega, O.B., Akinyemi, R.O., Zandian, H., Adham, D., Zahirian Moghadam, T., Advani, S.M., Teagle, W.L., Braithwaite, D., Agasthi, P., Saadatagah, S., Afshari, M., Agardh, E.E., Allebeck, P., Danielsson, A., Deuba, K., Carrero, J.J., Mohammad, D.K., Fereshtehnejad, S., Ärnlöv, J., Nowak, C., Cederroth, C.R., Ahmadi, A., Pathak, A., Mills, E.J., Kurmi, O.P., Olagunju, A.T., Agarwal, G., Sathish, T., Aghaali, M., Mohammadbeigi, A., Agrawal, A., Ahmad, T., Ahmadi, K., Maleki, S., Naderi, M., Salahshoor, M.R., Pourmirza Kalhori, R., Almasi, A., Salimi, Y., Siabani, S., Ziapour, A., Barzegar, A., Khazaie, H., Kianipour, N., Amiri, F., Salehi Zahabi, S., Mirzaei, M., Shamsi, M., Najafi, F., Jalali, A., Ghadiri, K., Heydarpour, F., Fattahi, N., Karami Matin, B., Kazemi Karyani, A., Pirsaheb, M., Rajati, F., Sadeghi, E., Safari, Y., Sharafi, K., Soltani, S., Vasseghian, Y., Atafar, Z., Jalilian, F., Mirzaei-Alavijeh, M., Saeidi, S., Soofi, M., Zangeneh, A., Mansouri, B., Ahmadi, M., Khafaie, M.A., Safiri, S., Moghadaszadeh, M., Asghari Jafarabadi, M., Doshmangir, L., Jadidi-Niaragh, F., Ghafourifard, M., Spotin, A., Khodayari, M., Samadi Kafil, H., Kalankesh, L.R., Ahmadpour, E., Yousefi, B., Ansari, F., Hassankhani, H., Karimi, S., Haririan, H., Mereta, S., Ahmed, M.B., Feyissa, G.T., Ciobanu, L.G., Aji, B., Aynalem, G.L., Gebresillassie, B., Tefera, Y.G., Akalu, T.Y., Baraki, A.G., Tesema, G.A., Tessema, Z.T., Tamiru, A.T., Azene, Z.N., Netsere, H.B., Yano, Y., Akinyemiju, T., Wu, C., Zadey, S., Samad, Z., Ji, J.S., Doshi, P.P., John, O., Jha, V., Maulik, P.K., Pesudovs, K., Resnikoff, S., Mitchell, P.B., Sachdev, P.S., Akombi, B., Godinho, M.A., Ivers, R.Q., Peden, A.E., Biswas, R., Boufous, S., Akunna, C.J., Alahdab, F., Hammer, M.S., van Donkelaar, A., Al-Aly, Z., Dellavalle, R.P., Alam, S., Martin, R.V., Alam, N., De Leo, D., Tadakamadla, S.K., Alam, K., Alcalde-Rabanal, J.E., Avila-Burgos, L., Serván-Mori, E., Denova-Gutiérrez, E., Rodríguez-Ramírez, S., Morales, L., Poznańska, A., Wojtyniak, B., Rivera, J.A., Campos-Nonato, I.R., Campuzano Rincon, J., Sánchez-Pimienta, T.G., Mengesha, M.B., Welay, F.T., Alema, N.M., Demsie, D.G., Teame, H., Teklehaimanot, B.F., Alemu, B.W., Gultie, T., Bante, A.B., Yeshitila, Y.G., Geramo, Y.C.D., Glagn, M., Sorrie, M.B., W/hawariat, F.G., Amare, A., Kasa, A., Alemu, Y., Mihretie, K.M., Atnafu, D.D., Demeke, F.M., Melese, A., Bante, S.A., Dessie, G.A., Mengesha, E.W., Nigatu, D., Almadi, M.A.H., Alhabib, K.F., Mohammad, Y., Altirkawi, K.A., Temsah, M., Kugbey, N., Ayanore, M.A., Alhassan, R.K., Ali, M., Ali, S., Alicandro, G., Kalhor, R., Alijanzadeh, M., Alinia, C., Yusefzadeh, H., Didarloo, A., Alizade, H., Nikpoor, A., Aljunid, S.M., Alla, F., Leal, L.F., Almasi-Hashiani, A., Moradzadeh, R., Zamanian, M., Nazari, J., Amini, S., Ghamari, F., Almasri, N.A., Khan, M., Al-Mekhlafi, H.M., Bedi, N., Alonso, J., Ciber, E.S.P., Al-Raddadi, R.M., Zakzuk, J., Alvis-Guzman, N., Alvis-Zakzuk, N.J., Castañeda-Orjuela, C.A., Malagón-Rojas, J.N., Gezae, K., Gesesew, H.A., Muthupandian, S., Gebremeskel, G.G., Berhe, K., Amare, B., Ayza, M.A., Gebremeskel, L.G., Gebreslassie, A.A.A., Bitew, H., Zewdie, K.A., Tela, F.G.G., Gill, T.K., Noubiap, J., Lassi, Z.S., Bhandari, D., Amit, A.L., Antonio, C.T., Faraon, E.A., Lopez, J.F., Atre, S.R., Ballew, S.H., Matsushita, K., Khoja, A.T., Daneshpajouhnejad, P., Ghadimi, M., Shafaat, O., Fanzo, J., Amugsi, D.A., Amul, G.H., Koh, D.S.Q., Venketasubramanian, N., Anbesu, E.W., Mohammed, J.A., Wondmeneh, T.G., Andrei, C., Negoi, R.I., Davitoiu, D.V., Manda, A., Negoi, I., Preotescu, L., Hostiuc, M., Hostiuc, S., Ancuceanu, R., Hasan, M., Leung, J., Anderlini, D., Mamun, A.A., Maravilla, J.C., McGrath, J.J., Lalloo, R., Uddin, R., Erskine, H.E., Knibbs, L.D., Mantilla Herrera, A.M., Santomauro, D.F., Mirica, A., Ausloos, M., Herteliu, C., Oţoiu, A., Pana, A., Andrei, T., Ştefan, S., Androudi, S., Angus, C., Ansari, I., Pourjafar, H., Shams-Beyranvand, M., Ansari-Moghaddam, A., Khammarnia, M., Antonazzo, I., Ferrara, P., Conti, S., Cortesi, P.A., Fornari, C., Lee, P.H., Antriyandarti, E., Yousefi, Z., Rafiei, A., Javidnia, J., Faridnia, R., Anvari, D., Goudarzian, A., Moosazadeh, M., Rezai, M., Daryani, A., Fareed, M., Anwer, R., Appiah, S., Paudel, D., Dichgans, M., Riahi, S., Rajabpour-Sanati, A., Arab-Zozani, M., Arba, A.A.K., Aremu, O., Ariani, F., Aripov, T., Armoon, B., Mahdavi, M.M., Arowosegbe, O.O., Tediosi, F., Aryal, K.K., Mosapour, A., Yaminfirooz, M., Arzani, A., Bijani, A., Jahani, M.A., Mouodi, S., Zamani, M., Asaad, M., Dianatinasab, M., Bahrami, M., Pakshir, K., Asadi-Pooya, A.A., Bayati, M., Shahabi, S., Athari, S., Atout, M.M.W., Atteraya, M.S., Brugha, T., Ausloos, F., Avokpaho, E.F.G., Room, R., Islam, M., Edvardsson, D., Rahman, M., Ayala Quintanilla, B., Gething, P.W., Briggs, A.M., Ayano, G., Hendrie, D., Miller, T.R., Azzopardi, P.S., Hoogar, P., B, D.B., Kulkarni, V., Kumar, N., Mithra, P., Shetty, R.S., Thapar, R., Padubidri, J., Bakkannavar, S.M., Nayak, V.C., Rastogi, P., Shetty, B.K., Bhageerathy, R., Gudi, N., Boloor, A., Holla, R., Rathi, P., Unnikrishnan, B., Janodia, M.D., Lang, J.J., Badawi, A., Orpana, H.M., Bhutta, Z.A., Shield, K.D., Chattu, V., Badiye, A.D., Kapoor, N., Bagherzadeh, M., Rabiee, N., Bagli, E., Baig, A.A., Bairwa, M., Lodha, R., Sagar, R., Rath, G.K., Bhardwaj, P., Charan, J., Kanchan, T., Joshi, A., Pakhare, A.P., Bakhshaei, M., Naghshtabrizi, B., Balachandran, A., Hoek, H.W., Postma, M.J., Geremew, A., Gebrehiwot, A.M., Balakrishnan, S., Desalew, A., Bojia, H.A., Mohammed, A.S., Regassa, L.D., Parmar, P.G.K., Balalla, S., Baldasseroni, A., Stokes, M.A., Ball, K., Islam, S., Maddison, R., Balzi, D., Levi, M., Banach, M., Banerjee, S.K., Banik, P.C., Barua, L., Faruque, M., Barboza, M.A., Barker-Collo, S.L., Jonas, J.B., Panda-Jonas, S., De Neve, J., Kohler, S., Moazen, B., Mohammed, S., Barrero, L.H., Basaleem, H., Bassat, Q., Haro, J.M., Koyanagi, A., Car, J., Greaves, F., Majeed, A., Davis, A.C., Steiner, T.J., Kusuma, D., Palladino, R., Rawaf, S., Saxena, S., Rawaf, D.L., Baune, B.T., Karch, A., Baye, B.A., Darega Gela, J., Kolola, T., Becker, J.S., DeLang, M., West, J., Gad, M.M., Serre, M.L., Gallus, S., Lugo, A., Beghi, E., Pupillo, E., Bosetti, C., Giussani, G., Bikbov, B., Perico, N., Remuzzi, G., Imani-Nasab, M., Nouraei Motlagh, S., Sharafi, Z., Behzadifar, M., Béjot, Y., Bekuma, T.T., Yilma, M.T., Bell, M.L., Bello, A.K., Rafiee, A., Keddie, S.H., Lucas, T.C.D., Dolecek, C., Dunachie, S.J., Rumisha, S.F., Weiss, D.J., Lewington, S., Collins, E.L., Nandi, A.K., Zhao, Y., Bennett, D.A., Karim, M.A., Lacey, B., Khundkar, R., Yaya, S., Goulart, A.C., Santos, I.S., Bensenor, I.M., Lotufo, P.A., Tovani-Palone, M.R., Castaldelli-Maia, J., Wang, Y., Furtado, J.M., Benziger, C.P., Berman, A.E., Mazidi, M., Bernabe, E., Dargan, P.I., Molokhia, M., Shibuya, K., Douiri, A., Wolfe, C.D.A., Hay, R.J., Flohr, C., Suchdev, P.S., Ram, P., Bernstein, R.S., Liu, Y., Bhagavathula, A.S., Khan, G., Grivna, M., Bhala, N., Chandan, J.S., Gaidhane, A.M., Quazi Syed, Z., Saxena, D., Khatib, M., Bhat, A.G., Bhattacharyya, K., Bhattarai, S., Das, J.K., Bibi, S., Bilano, V., Bin Sayeed, M., Cherbuin, N., D'Amico, E., Grosso, G., Borzì, A.M., Biondi, A., Vacante, M., Valli, A., Birihane, B.M., Bisanzio, D., Hassan, S., Bjørge, T., Øverland, S., Bockarie, M.J., Mensah, G.A., Sliwa, K., Gholamian, A., Bohlouli, S., Esmaeilnejad, S., Bohluli, M., Bolla, S.R., Borges, G., Bose, D., Bourne, R., Brayne, C., Breitborde, N.J.K., Fisher, J.L., Breitner, S., Brenner, H., Breusov, A.V., Rakovac, I., Briko, 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Babale, Suliankatchi Abdulkader, Rizwan, Sykes, Bryan L, Tabarés-Seisdedos, Rafael, Tabb, Karen M, Tadakamadla, Santosh Kumar, Taherkhani, Amir, Tang, Muming, Taveira, Nuno, Taylor, Heather Jean, Teagle, Whitney L, Tehrani-Banihashemi, Arash, Teklehaimanot, Berhane Fseha, Tessema, Zemenu Tadesse, Thankappan, Kavumpurathu Raman, Thomas, Nihal, Thrift, Amanda G, Titova, Mariya Vladimirovna, Tohidinik, Hamid Reza, Tonelli, Marcello, Topor-Madry, Roman, Topouzis, Foti, Tovani-Palone, Marcos Roberto Roberto, Traini, Eugenio, Tran, Bach Xuan, Travillian, Ravensara, Trias-Llimós, Sergi, Truelsen, Thomas Clement, Tudor Car, Lorainne, Unnikrishnan, Bhaskaran, Upadhyay, Era, Vacante, Marco, Vakilian, Alireza, Valdez, Pascual R, Valli, Alessandro, Vardavas, Constantine, Vasankari, Tommi Juhani, Vasconcelos, Ana Maria Nogale, Vasseghian, Yasser, Veisani, Yousef, Venketasubramanian, Narayanaswamy, Vidale, Simone, Violante, Francesco S, Vlassov, Vasily, Vollset, Stein Emil, Vos, Theo, Vujcic, Isidora S, Vukovic, Ana, Vukovic, Rade, Waheed, Yasir, Wallin, Mitchell Taylor, Walters, Magdalene K, Wang, Hongbo, Wang, Yuan-Pang, Watson, Stefanie, Wei, Jingkai, Weiss, Jordan, Weldesamuel, Girmay Teklay, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A, Wiangkham, Taweewat, Wiens, Kirsten E, Wijeratne, Tissa, Wiysonge, Charles Shey, Wojtyniak, Bogdan, Wolfe, Charles D A, Wondmieneh, Adam Belay, Wool, Eve E, Wu, Ai-Min, Wu, Junjie, Xu, Gelin, Yamada, Tomohide, Yamagishi, Kazumasa, Yano, Yuichiro, Yaya, Sanni, Yazdi-Feyzabadi, Vahid, Yearwood, Jamal A, Yeheyis, Tomas Y, Yilgwan, Christopher Sabo, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Yoosefi Lebni, Javad, York, Hunter W, Younis, Mustafa Z, Younker, Theodore Patrick, Yousefi, Zabihollah, Yousefinezhadi, Taraneh, Yousuf, Abdilahi Yousuf, Yusefzadeh, Hasan, Zahirian Moghadam, Telma, Zakzuk, Josefina, Zaman, Sojib Bin, Zamani, Mohammad, Zamanian, Maryam, Zandian, Hamed, Zhang, Zhi-Jiang, Zheng, Peng, Zhou, Maigeng, Ziapour, Arash, Murray, Christopher J L, Collaborators, GBD 2019 Demographics, GBD 2019 Demographics Collaborator, Violante FS, Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Microbes in Health and Disease (MHD), Department of Earth Systems Analysis, Biomechanical Engineering, TechMed Centre, Biomolecular Nanotechnology, Research Methodology, Measurement and Data Analysis, Materials Science and Technology of Polymers, Inorganic Materials Science, MESA+ Institute, Biomedical and Environmental Sensorsystems, Mesoscale Chemical Systems, Faculty of Engineering Technology, Nonlinear Solid Mechanics, Digital Society Institute, Pervasive Systems, Nanobiophysics, Faculty of Geo-Information Science and Earth Observation, Multi Scale Mechanics, Engineering Fluid Dynamics, Physics of Complex Fluids, Developmental BioEngineering, Physics of Fluids, Elastomer Technology and Engineering, Medical Cell Biophysics, European Membrane Institute, Department of Earth Observation Science, Biomaterials Science and Technology, Sustainable Process Technology, Department of Urban and Regional Planning and Geo-Information Management, Department of Natural Resources, XUV Optics, Databases (Former), Department of Water Resources, Psychology, Health & Technology, Membrane Science & Technology, Department of Public Health, Clinicum, HUS Neurocenter, HUS Comprehensive Cancer Center, and Environmental Sciences
Subjects: Male, very elderly, Demographic transition, HALE, 030204 cardiovascular system & hematology, preschool child, Global Burden of Disease, Carga Global de Enfermedades, 0302 clinical medicine, newborn, Risk Factors, Surveys and Questionnaires, and Risk Factors Study, 80 and over, 030212 general & internal medicine, Birth Rate, Child, Migration, 11 Medical and Health Sciences, Aged, 80 and over, education.field_of_study, Injuries, Geography, Mortality rate, 1. No poverty, DEATH, Censuses, General Medicine, SDG 10 - Reduced Inequalities, Middle Aged, Demographic analysis, 3142 Public health care science, environmental and occupational health, 3. Good health, demographic analysis, Estilo de Vida Saludable, risk factor, Child, Preschool, Demography/statistics & numerical data, Global Burden of Diseases, Injuries, Risk Factors, Fertility, Mortality, Migration, Population, epidemiology, Female, A990 Medicine and Dentistry not elsewhere classified, CHILD-MORTALITY, Live Birth, Global Health Metrics, TRANSITION, demographics, GBD, fertility, mortality, hale, Adult, Adolescent, Total fertility rate, Population, Global Burden of Diseases, Injuries, and Risk Factors Study, Birth rate, 03 medical and health sciences, Young Adult, Life Expectancy, SDG 3 - Good Health and Well-being, General & Internal Medicine, SYSTEMATIC ANALYSIS, Demografía, Humans, Global Burden of Disease Study, human, Mortality, education, Preschool, Aged, Demography, Spatial Analysis, questionnaire, Infant, Newborn, Klinisk medicin, HIV, Infant, Global Burden of Diseases, sex-specific fertility, Live Birth/epidemiology, purl.org/pe-repo/ocde/ford#3.02.00 [https], MODEL, Fertilidad, Fertility, Demographic change, Life expectancy, NA, global disease burden, Clinical Medicine, population research
Abstract: Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Methods 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate age-specific fertility rates for 5-year age groups between ages 15 and 49 years. With extensions to age groups 10-14 and 50-54 years, the total fertility rate (TFR) was then aggregated using the estimated age-specific fertility between ages 10 and 54 years. 7417 sources were used for under-5 mortality estimation and 7355 for adult mortality. ST-GPR was used to synthesise data sources after correction for known biases. Adult mortality was measured as the probability of death between ages 15 and 60 years based on vital registration, sample registration, and sibling histories, and was also estimated using ST-GPR. HIV-free life tables were then estimated using estimates of under-5 and adult mortality rates using a relational model life table system created for GBD, which closely tracks observed age-specific mortality rates from complete vital registration when available. Independent estimates of HIV-specific mortality generated by an epidemiological analysis of HIV prevalence surveys and antenatal clinic serosurveillance and other sources were incorporated into the estimates in countries with large epidemics. Annual and single-year age estimates of net migration and population for each country and territory were generated using a Bayesian hierarchical cohort component model that analysed estimated age-specific fertility and mortality rates along with 1250 censuses and 747 population registry years. We classified location-years into seven categories on the basis of the natural rate of increase in population (calculated by subtracting the crude death rate from the crude birth rate) and the net migration rate. We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. Uncertainty was propagated throughout the demographic estimation process, including fertility, mortality, and population, with 1000 draw-level estimates produced for each metric. Findings The global TFR decreased from 2.72 (95% uncertainty interval [UI] 2.66-2.79) in 2000 to 2.31 (2.17-2.46) in 2019. Global annual livebirths increased from 134.5 million (131.5-137.8) in 2000 to a peak of 139.6 million (133.0-146.9) in 2016. Global livebirths then declined to 135.3 million (127.2-144.1) in 2019. Of the 204 countries and territories included in this study, in 2019, 102 had a TFR lower than 2.1, which is considered a good approximation of replacement-level fertility. All countries in sub-Saharan Africa had TFRs above replacement level in 2019 and accounted for 27.1% (95% UI 26.4-27.8) of global livebirths. Global life expectancy at birth increased from 67.2 years (95% UI 66.8-67.6) in 2000 to 73.5 years (72.8-74.3) in 2019. The total number of deaths increased from 50.7 million (49.5-51.9) in 2000 to 56.5 million (53.7-59.2) in 2019. Under-5 deaths declined from 9.6 million (9.1-10.3) in 2000 to 5.0 million (4.3-6.0) in 2019. Global population increased by 25.7%, from 6.2 billion (6.0-6.3) in 2000 to 7.7 billion (7.5-8.0) in 2019. In 2019, 34 countries had negative natural rates of increase; in 17 of these, the population declined because immigration was not sufficient to counteract the negative rate of decline. Globally, HALE increased from 58.6 years (56.1-60.8) in 2000 to 63.5 years (60.8-66.1) in 2019. HALE increased in 202 of 204 countries and territories between 2000 and 2019. Interpretation Over the past 20 years, fertility rates have been dropping steadily and life expectancy has been increasing, with few exceptions. Much of this change follows historical patterns linking social and economic determinants, such as those captured by the GBD Socio-demographic Index, with demographic outcomes. More recently, several countries have experienced a combination of low fertility and stagnating improvement in mortality rates, pushing more populations into the late stages of the demographic transition. Tracking demographic change and the emergence of new patterns will be essential for global health monitoring. Copyright (C) 2020 The Author(s). Published by Elsevier Ltd.
Published: 2020

3. Conversion of urine protein-creatinine ratio or urine dipstick protein to urine albumin-creatinine ratio for use in chronic kidney disease screening and prognosis: An individual participant-based meta-analysis.

Author: Sumida K., Nadkarni G.N., Grams M.E., Sang Y., Ballew S.H., Coresh J., Matsushita K., Surapaneni A., Brunskill N., Chadban S.J., Chang A.R., Cirillo M., Daratha K.B., Gansevoort R.T., Garg A.X., Iacoviello L., Kayama T., Konta T., Kovesdy C.P., Lash J., Lee B.J., Major R.W., Metzger M., Miura K., Naimark D.M.J., Nelson R.G., Sawhney S., Stempniewicz N., Tang M., Townsend R.R., Traynor J.P., Valdivielso J.M., Wetzels J., Polkinghorne K.R., Heerspink H.J.L., Sumida K., Nadkarni G.N., Grams M.E., Sang Y., Ballew S.H., Coresh J., Matsushita K., Surapaneni A., Brunskill N., Chadban S.J., Chang A.R., Cirillo M., Daratha K.B., Gansevoort R.T., Garg A.X., Iacoviello L., Kayama T., Konta T., Kovesdy C.P., Lash J., Lee B.J., Major R.W., Metzger M., Miura K., Naimark D.M.J., Nelson R.G., Sawhney S., Stempniewicz N., Tang M., Townsend R.R., Traynor J.P., Valdivielso J.M., Wetzels J., Polkinghorne K.R., and Heerspink H.J.L.
Abstract: Background: Although measuring albuminuria is the preferred method for defining and staging chronic kidney disease (CKD), total urine protein or dipstick protein is often measured instead. Objective(s): To develop equations for converting urine protein-creatinine ratio (PCR) and dipstick protein to urine albumin-creatinine ratio (ACR) and to test their diagnostic accuracy in CKD screening and staging. Design(s): Individual participant-based meta-analysis. Setting(s): 12 research and 21 clinical cohorts. Participant(s): 919 383 adults with same-day measures of ACR and PCR or dipstick protein. Measurements: Equations to convert urine PCR and dipstick protein to ACR were developed and tested for purposes of CKD screening (ACR >=30 mg/g) and staging (stage A2: ACR of 30 to 299 mg/g; stage A3: ACR >=300 mg/g). Result(s): Median ACR was 14 mg/g (25th to 75th percentile of cohorts, 5 to 25 mg/g). The association between PCR and ACR was inconsistent for PCR values less than 50 mg/g. For higher PCR values, the PCR conversion equations demonstrated moderate sensitivity (91%, 75%, and 87%) and specificity (87%, 89%, and 98%) for screening (ACR >30 mg/g) and classification into stages A2 and A3, respectively. Urine dipstick categories of trace or greater, trace to +, and ++ for screening for ACR values greater than 30 mg/g and classification into stages A2 and A3, respectively, had moderate sensitivity (62%, 36%, and 78%) and high specificity (88%, 88%, and 98%). For individual risk prediction, the estimated 2-year 4-variable kidney failure risk equation using predicted ACR from PCR had discrimination similar to that of using observed ACR. Limitation(s): Diverse methods of ACR and PCR quantification were used; measurements were not always performed in the same urine sample. Conclusion(s): Urine ACR is the preferred measure of albuminuria; however, if ACR is not available, predicted ACR from PCR or urine dipstick protein may help in CKD screening, staging, and prognosis. Primary
Published: 2021

4. Conversion of Urine Protein-Creatinine Ratio or Urine Dipstick Protein to Urine Albumin-Creatinine Ratio for Use in Chronic Kidney Disease Screening and Prognosis : An Individual Participant-Based Meta-analysis

Author: Sumida, K., Nadkarni, G.N., Grams, M.E., Sang, Y., Ballew, Shoshana H., Coresh, J., Matsushita, K., Surapaneni, A., Brunskill, N., Chadban, S.J., Chang, A.R., Cirillo, M., Daratha, K.B., Gansevoort, R.T., Garg, A.X., Iacoviello, L., Kayama, T., Konta, T., Kovesdy, C.P., Lash, J., Lee, B.J., Major, R.W., Metzger, M., Miura, K., Naimark, D.M.J., Nelson, R.G., Sawhney, S., Stempniewicz, N., Tang, M., Townsend, R.R., Traynor, J.P., Valdivielso, J.M., Wetzels, J., Polkinghorne, K.R., Heerspink, H.J., Sumida, K., Nadkarni, G.N., Grams, M.E., Sang, Y., Ballew, Shoshana H., Coresh, J., Matsushita, K., Surapaneni, A., Brunskill, N., Chadban, S.J., Chang, A.R., Cirillo, M., Daratha, K.B., Gansevoort, R.T., Garg, A.X., Iacoviello, L., Kayama, T., Konta, T., Kovesdy, C.P., Lash, J., Lee, B.J., Major, R.W., Metzger, M., Miura, K., Naimark, D.M.J., Nelson, R.G., Sawhney, S., Stempniewicz, N., Tang, M., Townsend, R.R., Traynor, J.P., Valdivielso, J.M., Wetzels, J., Polkinghorne, K.R., and Heerspink, H.J.
Abstract: Item does not contain fulltext, BACKGROUND: Although measuring albuminuria is the preferred method for defining and staging chronic kidney disease (CKD), total urine protein or dipstick protein is often measured instead. OBJECTIVE: To develop equations for converting urine protein-creatinine ratio (PCR) and dipstick protein to urine albumin-creatinine ratio (ACR) and to test their diagnostic accuracy in CKD screening and staging. DESIGN: Individual participant-based meta-analysis. SETTING: 12 research and 21 clinical cohorts. PARTICIPANTS: 919 383 adults with same-day measures of ACR and PCR or dipstick protein. MEASUREMENTS: Equations to convert urine PCR and dipstick protein to ACR were developed and tested for purposes of CKD screening (ACR ≥30 mg/g) and staging (stage A2: ACR of 30 to 299 mg/g; stage A3: ACR ≥300 mg/g). RESULTS: Median ACR was 14 mg/g (25th to 75th percentile of cohorts, 5 to 25 mg/g). The association between PCR and ACR was inconsistent for PCR values less than 50 mg/g. For higher PCR values, the PCR conversion equations demonstrated moderate sensitivity (91%, 75%, and 87%) and specificity (87%, 89%, and 98%) for screening (ACR >30 mg/g) and classification into stages A2 and A3, respectively. Urine dipstick categories of trace or greater, trace to +, and ++ for screening for ACR values greater than 30 mg/g and classification into stages A2 and A3, respectively, had moderate sensitivity (62%, 36%, and 78%) and high specificity (88%, 88%, and 98%). For individual risk prediction, the estimated 2-year 4-variable kidney failure risk equation using predicted ACR from PCR had discrimination similar to that of using observed ACR. LIMITATION: Diverse methods of ACR and PCR quantification were used; measurements were not always performed in the same urine sample. CONCLUSION: Urine ACR is the preferred measure of albuminuria; however, if ACR is not available, predicted ACR from PCR or urine dipstick protein may help in CKD screening, staging, and prognosis. PRIMARY FUNDING SOURCE: Nati
Published: 2020

5. Five insights from the Global Burden of Disease Study 2019.

Author: Hamadeh R.R., Soyiri I.N., Sreeramareddy C.T., Srinivasan V., Sripada K., Stovner L.J., Stockfelt L., Sultan I., Swope C.B., Vaicekonyte R., Sykes B.L., Szumowski L., Tabb K.M., Tabuchi T., Taddele B.W., Tahir Z., Tareque M.I., Tarigan I.U., Taveira N., Thankappan K.R., Thomas N., Varughese S., Touvier M., Tran B.X., Tsatsakis A., Vardavas C., Ullah I., Umeokonkwo C.D., Undurraga E.A., Upadhyay E., Vasankari T.J., Vasconcelos A.N., Veisani Y., Vidale S., Waheed Y., Wei J., Wang F., Zhao X.G., Wang Y., Yu C., Zhang Z., Wang H., Weiss J., Wiangkham T., Wickramasinghe N.D., Wu A., Xie Y., Xu G., Yahyazadeh Jabbari S., Yilgwan C.S., Yonemoto N., Younis M.Z., Younker T.P., Yu Y., Zaidi S., Zhang J., Zhang Y., Zheleva B., Zhu C., Abbafati C., Machado D.B., Cislaghi B., Salman O.M., Karanikolos M., McKee M., Abbas K.M., Brady O.J., Larson H.J., Trias-Llimos S., Cummins S., Langan S.M., Sartorius B., Hafiz A., Jenabi E., Mohammad Gholi Mezerji N., Borzouei S., Azarian G., Khazaei S., Abbasi M., Asghari B., Masoumi S., Komaki H., Taherkhani A., Adabi M., Abbasifard M., Bazmandegan G., Kamiab Z., Vakilian A., Anjomshoa M., Mokari A., Sabour S., Shahbaz M., Saeedi R., Ahmadieh H., Yousefinezhadi T., Haj-Mirzaian A., Nikbakhsh R., Safi S., Asgari S., Irvani S.N., Jahanmehr N., Ramezanzadeh K., Abbasi-Kangevari M., Khayamzadeh M., Abbastabar H., Shirkoohi R., Fazlzadeh M., Janjani H., Hosseini M., Mansournia M., Tohidinik H., Bakhtiari A., Fazaeli A., Mousavi S., Hasanzadeh A., Nabavizadeh B., Malekzadeh R., Hashemian M., Pourshams A., Salimzadeh H., Sepanlou S.G., Afarideh M., Esteghamati A., Esteghamati S., Ghajar A., Heidari B., Rezaei N., Mohamadi E., Rahimi-Movaghar A., Rahim F., Eskandarieh S., Sahraian M., Mohebi F., Aminorroaya A., Ebrahimi H., Farzadfar F., Mohajer B., Pishgar F., Saeedi Moghaddam S., Shabani M., Zarafshan H., Abolhassani H., Hafezi-Nejad N., Heidari-Soureshjani R., Abdollahi M., Farahmand M., Salamati P., Mehrabi Nasab E., Tajdini M., Aghamir S., Mirzaei R., Dibaji Forooshani Z., Khater M.M., Abd-Allah F., Abdelalim A., Abualhasan A., El-Jaafary S.I., Hassan A., Elsharkawy A., Khater A.M., Elhabashy H.R., Salem M.R.R., Salem H., Sadeghi M., Jafarinia M., Amini-Rarani M., Mohammadifard N., Sarrafzadegan N., Abdollahpour I., Sarveazad A., Tehrani-Banihashemi A., Yoosefi Lebni J., Manafi N., Pazoki Toroudi H., Dorostkar F., Alipour V., Sheikhtaheri A., Arabloo J., Azari S., Ghashghaee A., Rezapour A., Naserbakht M., Kabir A., Mehri F., Yousefifard M., Asadi-Aliabadi M., Babaee E., Eshrati B., Goharinezhad S., Moradi M., Abedi P., Rashedi V., Kumar V., Elgendy I.Y., Basu S., Park J., Pereira A., Norheim O.F., Eagan A.W., Cahill L.E., Sheikh A., Abushouk A.I., Thakur B., Barnighausen T.W., Shrime M.G., Abedi A., Doshi C.P., Abegaz K.H., Geberemariyam B.S., Aynalem Y.A., Shiferaw W.S., Abosetugn A.E., Aboyans V., Abrams E.M., Gitimoghaddam M., Kissoon N., Stubbs J.L., Brauer M., Iyamu I.O., Kopec J.A., Pourmalek F., Ribeiro A.P., Malta D.C., Gomez R.S., Abreu L.G., Abrigo M.R.M., Almulhim A.M., Dahlawi S.M.A., Pottoo F.H., Menezes R.G., Alanzi T.M., Alumran A.K., Abu Haimed A.K., Madadin M., Alanezi F.M., Abu-Gharbieh E., Saddik B., Abu-Raddad L.J., Samy A.M., El Nahas N., Shalash A.S., Nabhan A.F., Kamath A.M., Kassebaum N.J., Aravkin A.Y., Kochhar S., Sorensen R.J.D., Afshin A., Burkart K., Cromwell E.A., Gakidou E., Hay S.I., Kyu H.H., Lopez A.D., Lozano R., Misganaw A.T., Mokdad A.H., Naghavi M., Pigott D.M., Reiner Jr R.C., Roth G.A., Stanaway J.D., Vollset S., Vos T., Lim S.S., Murray C.J.L., Kalani R., Ikuta K.S., Cho D.Y., Kneib C.J., Crowe C.S., Massenburg B.B., Morrison S.D., Acebedo A., Adelson J.D., Agesa K.M., Alam T., Albertson S.B., Anderson J.A., Antony C.M., Ashbaugh C., Assmus M., Azhar G., Balassyano S., Bannick M.S., Barthelemy C.M., Bender R.G., Bennitt F.B., Bertolacci G.J., Biehl M.H., Bisignano C., Boon-Dooley A.S., Briant P.S., Bryazka D., Bumgarner B.R., Callender C.S., Cao J., Castle C.D., Castro E., Causey K., Cercy K.M., Chalek J., Cohen A.J., Comfort H., Compton K., Croneberger A.J., Cruz J.A., Cunningham M., Dangel W.J., Dean F.E., DeCleene N.K., Deen A., Degenhardt L., Dingels Z.V., Dippenaar I.N., Dirac M.A., Dolgert A.J., Emmons-Bell S., Estep K., Farag T., Feigin V.L., Feldman R., Ferrara G., Ferrari A.J., Fitzgerald R., Force L.M., Fox J.T., Frank T.D., Fu W., Fukutaki K., Fuller J.E., Fullman N., Galles N.C., Gardner W.M., Gershberg Hayoon A., Goren E., Gorman T.M., Gottlich H.C., Guo G., Haddock B., Hagins H., Haile L.M., Hamilton E.B., Han C., Han H., Harvey J.D., Henny K., Henrikson H.J., Henry N.J., Herbert M.E., Hsiao T., Huynh C.K., Iannucci V.C., Ippolito H., Irvine C.M.S., Jafari H., Jahagirdar D., James S.L., Johnson C.O., Johnson S.C., Keller C., Kemmer L., Kendrick P.J., Knight M., Kocarnik J.M., Krohn K.J., Larson S.L., Lau K.M., Ledesma J.R., Leever A.T., LeGrand K.E., Lescinsky H., Lin C., Liu H., Liu Z., Lo J., Lu A., Ma J., Maddison E.R., 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Abstract: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD 2019 incorporates data from 281 586 sources and provides more than 3.5 billion estimates of health outcome and health system measures of interest for global, national, and subnational policy dialogue. All GBD estimates are publicly available and adhere to the Guidelines on Accurate and Transparent Health Estimate Reporting. From this vast amount of information, five key insights that are important for health, social, and economic development strategies have been distilled. These insights are subject to the many limitations outlined in each of the component GBD capstone papers.Copyright © 2020 Elsevier Ltd
Published: 2020

6. Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019.

Author: Hird T.R., Shannawaz M., Sharma R., Shin J., Shiri R., Sierpinski R., Sigurvinsdottir R., Silva D.A.S., Simonetti B., Singh A., Sinha D.N., Skiadaresi E., Skou S.T., Skryabin V.Y., Zastrozhin M.S., Soheili A., Sokhan A., Somefun O.D., Korotkova A.V., Soyiri I.N., Sreeramareddy C.T., Srinivasan V., Sripada K., Stovner L.J., Stockfelt L., Sultan I., Swope C.B., Vaicekonyte R., Sykes B.L., Szumowski L., Tabb K.M., Tabuchi T., Taddele B.W., Tahir Z., Tareque M.I., Tarigan I.U., Taveira N., Thankappan K.R., Thomas N., Varughese S., Touvier M., Tran B.X., Tsatsakis A., Vardavas C., Ullah I., Umeokonkwo C.D., Undurraga E.A., Upadhyay E., Vasankari T.J., Vasconcelos A.N., Veisani Y., Vidale S., Waheed Y., Wei J., Wang F., Zhao X.G., Wang Y., Yu C., Zhang Z., Wang H., Weiss J., Wiangkham T., Wickramasinghe N.D., Wu A., Xie Y., Xu G., Yahyazadeh Jabbari S., Yilgwan C.S., Yonemoto N., Younis M.Z., Younker T.P., Yu Y., Zaidi S., Zhang J., Zhang Y., Zheleva B., Zhu C., Abbafati C., Machado D.B., Cislaghi B., Salman O.M., Karanikolos M., McKee M., Abbas K.M., Brady O.J., Larson H.J., Trias-Llimos S., Cummins S., Langan S.M., Sartorius B., Hafiz A., Jenabi E., Mohammad Gholi Mezerji N., Borzouei S., Azarian G., Khazaei S., Abbasi M., Asghari B., Masoumi S., Komaki H., Taherkhani A., Adabi M., Abbasifard M., Bazmandegan G., Kamiab Z., Vakilian A., Anjomshoa M., Mokari A., Sabour S., Shahbaz M., Saeedi R., Ahmadieh H., Yousefinezhadi T., Haj-Mirzaian A., Nikbakhsh R., Safi S., Asgari S., Irvani S.N., Jahanmehr N., Ramezanzadeh K., Abbasi-Kangevari M., Khayamzadeh M., Abbastabar H., Shirkoohi R., Fazlzadeh M., Janjani H., Hosseini M., Mansournia M., Tohidinik H., Bakhtiari A., Fazaeli A., Mousavi S., Hasanzadeh A., Nabavizadeh B., Malekzadeh R., Hashemian M., Pourshams A., Salimzadeh H., Sepanlou S.G., Afarideh M., Esteghamati A., Esteghamati S., Ghajar A., Heidari B., Rezaei N., Mohamadi E., Rahimi-Movaghar A., Rahim F., Eskandarieh S., Sahraian M., Mohebi F., Aminorroaya 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Demoz G.T., Gebremeskel L.G., Woldu G., Handiso D., Dervenis N., Topouzis F., Desai R., Dharmaratne S.D., Dhungana G.P., Emamian M., Diaz D., Djalalinia S., Nguyen T.H., Vu G.T., Do H.T., Dokova K., Doku D.T., Neupane S., Takala J.S., Doxey M.C., Doyle K.E., Renzaho A.M.N., Ogbo F.A., Robinson S.R., Vukovic A., Ilic I.M., Santric-Milicevic M.M., Vujcic I.S., Dubljanin E., Vukovic R., Rasella D., Duraes A.R., Ebrahimi Kalan M., Effiong A., Pond C.D., Ehrlich J.R., Liu X., Wei M.Y.W., El Sayed I., El Tantawi M., El Sayed Zaki M., Elbarazi I., Tsai A.C., Elyazar I.R., Yazdi-Feyzabadi V., Eskandari K., Sharifi H., Halvaei I., Ghaffarifar F., Zaki L., Hasanpoor E., Esmaeilzadeh F., Etemadi A., Lan Q., Yeheyis T.Y., Etisso A.E., Ezekannagha O., e Farinha C.S., Farioli A., Violante F.S., Faris P.S., Mohammad D.K., Faro A., Lam J.O., Filip I., Fischer F., Flor L.S., Foigt N.A., Folayan M.O., Fomenkov A.A., Foroutan M., Francis J.M., Franklin R.C., Fukumoto T., Gamkrelidze A., Kereselidze M., 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H., Hossain N., Mai H.T., Nguyen C.T., Nguyen H.L.T., Pham H.Q., Nguyen D.N., Househ M., Hsairi M., Lin R., Hsieh V., Hwang B., Hu K., Humayun A., Hussain R., Ibeneme C.U., Ikeda N., Ilic M.D., Inbaraj L.R., Iqbal U., Islami F., Yamagishi K., Iso H., Iwu C.C.D., Jacobsen K.H., Jayatilleke A.U., Jeemon P., Jha R.P., Jia P., Osei F.B., Schutte A.E., Johansson L., Szocska M., Joo T., Jozwiak J.J., Jurisson M., Kabir Z., Roshandel G., Oladnabi M., Kalani H., Kassa G.M., Katikireddi S.V., Yamada T., Nomura S., Kawakami N., Kayode G.A., Kromhout H., Traini E., Kumar M., Keiyoro P.N., Muriithi M.K., Wamai R.G., Khader Y.S., Khalid N., Khan E.A., Khang Y., Khatab K., Khubchandani J., Yoon S., Shin M., Kim C., Kim Y., Kim D., Kimokoti R.W., Kinfu Y., Kisa S., Kisa A., Kissimova-Skarbek K., Topor-Madry R., Lallukka T., Meretoja T.J., Shivakumar K.M., Knudsen A.S., Sulo G., Kosen S., Kotlo A., Koul P.A., Krishan K., KS S., Kuate Defo B., Kucuk Bicer B., Yuce D., Rawat R., Meitei W.B., Kumar P., 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Moradi-Joo M., Morawska L., Mousavi Khaneghah A., Westerman R., Werdecker A., Mueller U.O., Mukhopadhyay S., Musa K., Mustafa G., Nagarajan A.J., Nagel G., Rothenbacher D., Naik G., Schwebel D.C., Singh J.A., Naimzada M., Otstavnov N., Otstavnov S.S., Soshnikov S., Titova M.V., Nair S., Naldi L., Nangia V., Nansseu J., Sobngwi E., Nguefack-Tsague G., Ndejjo R., Ngari K.N., Ngunjiri J.W., Nigatu Y.T., Oancea B., Oh I., Okunga E.W., Olusanya J.O., Olusanya B.O., Ong S., Onwujekwe O.E., Ortega-Altamirano D.V., Ortiz A., Soriano J.B., Osarenotor O., Ostojic S.M., Vlassov V., Pa M., Pangaribuan H.U., Park E., Pasupula D., Patel J.R., Patel S.K., Paternina-Caicedo A.J., Pathak M., Pathak A., Patten S.B., Tonelli M., Weintraub R.G., Paudel S., Pepito V.F., Thurston G.D., Peprah E.K., Pereira J., Pescarini J.M., Piccinelli C., Pilgrim T., Plass D., Pokhrel K.N., Prada S.I., Prakash V., Prakash S., Prasad N., Shigematsu M., Pribadi D.R.A., Sudaryanto A., Rabiee M., Radfar A., Ranabhat C.L., Ranta A., Ribeiro D.C., Rao S., Rawaf D.L., Rawal L., Renjith V., Rickard J., Roever L., Romoli M., Rostamian M., Rubagotti E., Rwegerera G.M., Ullah S., Sajadi S., Salam N., Salomon J.A., Salz I., Saraswathy S.Y., Sarmiento-Suarez R., Sathian B., Savic M., Saylan M., Schwendicke F., Sekerija M., Senthilkumaran S., Sha F., Shaheen A.A., Shaikh M.A., and Shamsizadeh M.
Abstract: Background: Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Method(s): 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate age-specific fertility rates for 5-year age groups between ages 15 and 49 years. With extensions to age groups 10-14 and 50-54 years, the total fertility rate (TFR) was then aggregated using the estimated age-specific fertility between ages 10 and 54 years. 7417 sources were used for under-5 mortality estimation and 7355 for adult mortality. ST-GPR was used to synthesise data sources after correction for known biases. Adult mortality was measured as the probability of death between ages 15 and 60 years based on vital registration, sample registration, and sibling histories, and was also estimated using ST-GPR. HIV-free life tables were then estimated using estimates of under-5 and adult mortality rates using a relational model life table system created for GBD, which closely tracks observed age-specific mortality rates from complete vital registration when available. Independent estimates of HIV-specific mortality generated by an epidemiological analysis of HIV prevalence surveys and antenatal clinic serosurveillance and other sources were incorporated into the estimates in countries with large epidemics. Annual and single-year age estimates of net migration and population for each country and territory were generated using a B
Published: 2020

7. PO-1188: Optimal radiotherapy strategy as risk-group in non-metastatic prostate cancer patients (KROG 18-15)

Author: Choi, S.H., primary, Kim, Y.S., additional, Yu, J., additional, Nam, T., additional, Kim, J., additional, Jang, B., additional, Kim, J.H., additional, Kim, Y., additional, Jung, B.K., additional, Chang, A.R., additional, Park, Y., additional, Lee, S.U., additional, Cho, K.H., additional, Kim, H., additional, Choi, Y., additional, Kim, Y.J., additional, Lee, D.S., additional, Shin, Y.J., additional, Shim, S.J., additional, Park, W., additional, and Cho, J., additional
Published: 2020
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8. Adiposity and risk of decline in glomerular filtration rate: meta-analysis of individual participant data in a global consortium

Author: Chang, A.R., Grams, M.E., Ballew, Shoshana H., Bilo, H., Correa, A., Evans, M., Gutierrez, O.M., Hosseinpanah, F., Iseki, K., Kenealy, T., Klein, B., Kronenberg, F., Lee, B.J., Li, Y., Miura, K., Navaneethan, S.D., Roderick, P.J., Valdivielso, J.M., Visseren, F.L., Zhang, L., Gansevoort, R.T., Hallan, S.I., Levey, A.S., Matsushita, K., Wetzels, J.F.M., Shalev, V., Woodward, M., Chang, A.R., Grams, M.E., Ballew, Shoshana H., Bilo, H., Correa, A., Evans, M., Gutierrez, O.M., Hosseinpanah, F., Iseki, K., Kenealy, T., Klein, B., Kronenberg, F., Lee, B.J., Li, Y., Miura, K., Navaneethan, S.D., Roderick, P.J., Valdivielso, J.M., Visseren, F.L., Zhang, L., Gansevoort, R.T., Hallan, S.I., Levey, A.S., Matsushita, K., Wetzels, J.F.M., Shalev, V., and Woodward, M.
Abstract: Contains fulltext : 203008.pdf (publisher's version ) (Open Access), OBJECTIVE: To evaluate the associations between adiposity measures (body mass index, waist circumference, and waist-to-height ratio) with decline in glomerular filtration rate (GFR) and with all cause mortality. DESIGN: Individual participant data meta-analysis. SETTING: Cohorts from 40 countries with data collected between 1970 and 2017. PARTICIPANTS: Adults in 39 general population cohorts (n=5 459 014), of which 21 (n=594 496) had data on waist circumference; six cohorts with high cardiovascular risk (n=84 417); and 18 cohorts with chronic kidney disease (n=91 607). MAIN OUTCOME MEASURES: GFR decline (estimated GFR decline >/=40%, initiation of kidney replacement therapy or estimated GFR <10 mL/min/1.73 m(2)) and all cause mortality. RESULTS: Over a mean follow-up of eight years, 246 607 (5.6%) individuals in the general population cohorts had GFR decline (18 118 (0.4%) end stage kidney disease events) and 782 329 (14.7%) died. Adjusting for age, sex, race, and current smoking, the hazard ratios for GFR decline comparing body mass indices 30, 35, and 40 with body mass index 25 were 1.18 (95% confidence interval 1.09 to 1.27), 1.69 (1.51 to 1.89), and 2.02 (1.80 to 2.27), respectively. Results were similar in all subgroups of estimated GFR. Associations weakened after adjustment for additional comorbidities, with respective hazard ratios of 1.03 (0.95 to 1.11), 1.28 (1.14 to 1.44), and 1.46 (1.28 to 1.67). The association between body mass index and death was J shaped, with the lowest risk at body mass index of 25. In the cohorts with high cardiovascular risk and chronic kidney disease (mean follow-up of six and four years, respectively), risk associations between higher body mass index and GFR decline were weaker than in the general population, and the association between body mass index and death was also J shaped, with the lowest risk between body mass index 25 and 30. In all cohort types, associations between higher waist circumference and higher waist-to-heig
Published: 2019

9. Evaluating Glomerular Filtration Rate Slope as a Surrogate End Point for ESKD in Clinical Trials: An Individual Participant Meta-Analysis of Observational Data

Author: Grams, M.E., Sang, Y., Ballew, Shoshana H., Matsushita, K., Astor, B.C., Carrero, J.J., Chang, A.R., Inker, L.A., Kenealy, T., Kovesdy, C.P., Lee, B.J., Levin, A., Naimark, D., Pena, M.J., Schold, J.D., Shalev, V., Wetzels, J.F.M., Woodward, M., Gansevoort, R.T., Levey, A.S., Coresh, J., Grams, M.E., Sang, Y., Ballew, Shoshana H., Matsushita, K., Astor, B.C., Carrero, J.J., Chang, A.R., Inker, L.A., Kenealy, T., Kovesdy, C.P., Lee, B.J., Levin, A., Naimark, D., Pena, M.J., Schold, J.D., Shalev, V., Wetzels, J.F.M., Woodward, M., Gansevoort, R.T., Levey, A.S., and Coresh, J.
Abstract: Item does not contain fulltext, BACKGROUND: Decline in eGFR is a biologically plausible surrogate end point for the progression of CKD in clinical trials. However, it must first be tested to ensure strong associations with clinical outcomes in diverse populations, including patients with higher eGFR. METHODS: To investigate the association between 1-, 2-, and 3-year changes in eGFR (slope) with clinical outcomes over the long term, we conducted a random effects meta-analysis of 3,758,551 participants with baseline eGFR>/=60 ml/min per 1.73 m(2) and 122,664 participants with eGFR<60 ml/min per 1.73 m(2) from 14 cohorts followed for an average of 4.2 years. RESULTS: Slower eGFR decline by 0.75 ml/min per 1.73 m(2) per year over 2 years was associated with lower risk of ESKD in participants with baseline eGFR>/=60 ml/min per 1.73 m(2) (adjusted hazard ratio, 0.70; 95% CI, 0.68 to 0.72) and eGFR<60 ml/min per 1.73 m(2) (0.71; 95% CI, 0.68 to 0.74). The relationship was stronger with 3-year slope. For a rapidly progressing population with predicted 5-year risk of ESKD of 8.3%, an intervention that reduced eGFR decline by 0.75 ml/min per 1.73 m(2) per year over 2 years would reduce the ESKD risk by 1.6%. For a hypothetical low-risk population with a predicted 5-year ESKD risk of 0.58%, the same intervention would reduce the risk by only 0.13%. CONCLUSIONS: Slower decline in eGFR was associated with lower risk of subsequent ESKD, even in participants with eGFR>/=60 ml/min per 1.73 m(2), but those with the highest risk would be expected to benefit the most.
Published: 2019

10. Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies.

Author: Ichikawa K., Collins J.F., Drury P.L., Ellis S.G., Nadukuru R., Metzger M., Flamant M., Houillier P., Haymann J.-P., Froissart M., Kenealy T., Elley R.C., Cuddeback J.K., Ciemins E.L., Stempniewicz R., Nelson R.G., Knowler W.C., Bakker S.J., Major R.W., Medcalf J.F., Shepherd D., Barrett-Connor E., Bergstrom J., Ix J.H., Molnar M.Z., Maciulaitis R., Manley T., Smith K., Stockbridge N., Thompson A., Vetter T., Willis K., Zhang L., Coresh J., Heerspink H.J.L., Sang Y., Matsushita K., Arnlov J., Astor B.C., Black C., Brunskill N.J., Carrero J.-J., Feldman H.I., Fox C.S., Inker L.A., Ishani A., Ito S., Jassal S., Konta T., Polkinghorne K., Romundstad S., Solbu M.D., Stempniewicz N., Stengel B., Tonelli M., Umesawa M., Waikar S.S., Wen C.-P., Wetzels J.F.M., Woodward M., Grams M.E., Kovesdy C.P., Levey A.S., Gansevoort R.T., Appel L.J., Greene T., Chen T.K., Chalmers J., Arima H., Perkovic V., Levin A., Djurdjev O., Tang M., Nally J., Navaneethan S.D., Schold J.D., Weldegiorgis M., Herrington W.G., Smith M., Hsu C.Y., Hwang S.-J., Chang A.R., Kirchner H.L., Green J.A., Ho K., Marks A., Prescott G., Clark L.E., Fluck N., Shalev V., Chodick G., Blankestijn P.J., Van Zuilen A., Van den Brand J.A., Sarnak M.J., Bottinger E., Nadkarni G.N., Sumida K., de Zeeuw D., Brenner B., Qureshi A.R., Elinder C.-G., Runesson B., Evans M., Segelmark M., Stendahl M., Schon S., Naimark D.M., Tangri N., Sud M., Hirayama A., Bilo H.J., Landman G.W., Van Hateren K.J., Kleefstra N., Hallan S.I., Ballew S.H., Chen J., Kwak L., Surapaneni A., Parving H.-H., Rodby R.A., Rohde R.D., Lewis J.B., Lewis E., Perrone R.D., Abebe K.Z., Hou F.F., Xie D., Hunsicker L.G., Imai E., Kobayashi F., Makino H., Remuzzi G., Ruggenenti P., Eckardt K.-U., Gudmundsdottir H., Ichikawa K., Collins J.F., Drury P.L., Ellis S.G., Nadukuru R., Metzger M., Flamant M., Houillier P., Haymann J.-P., Froissart M., Kenealy T., Elley R.C., Cuddeback J.K., Ciemins E.L., Stempniewicz R., Nelson R.G., Knowler W.C., Bakker S.J., Major R.W., Medcalf J.F., Shepherd D., Barrett-Connor E., Bergstrom J., Ix J.H., Molnar M.Z., Maciulaitis R., Manley T., Smith K., Stockbridge N., Thompson A., Vetter T., Willis K., Zhang L., Coresh J., Heerspink H.J.L., Sang Y., Matsushita K., Arnlov J., Astor B.C., Black C., Brunskill N.J., Carrero J.-J., Feldman H.I., Fox C.S., Inker L.A., Ishani A., Ito S., Jassal S., Konta T., Polkinghorne K., Romundstad S., Solbu M.D., Stempniewicz N., Stengel B., Tonelli M., Umesawa M., Waikar S.S., Wen C.-P., Wetzels J.F.M., Woodward M., Grams M.E., Kovesdy C.P., Levey A.S., Gansevoort R.T., Appel L.J., Greene T., Chen T.K., Chalmers J., Arima H., Perkovic V., Levin A., Djurdjev O., Tang M., Nally J., Navaneethan S.D., Schold J.D., Weldegiorgis M., Herrington W.G., Smith M., Hsu C.Y., Hwang S.-J., Chang A.R., Kirchner H.L., Green J.A., Ho K., Marks A., Prescott G., Clark L.E., Fluck N., Shalev V., Chodick G., Blankestijn P.J., Van Zuilen A., Van den Brand J.A., Sarnak M.J., Bottinger E., Nadkarni G.N., Sumida K., de Zeeuw D., Brenner B., Qureshi A.R., Elinder C.-G., Runesson B., Evans M., Segelmark M., Stendahl M., Schon S., Naimark D.M., Tangri N., Sud M., Hirayama A., Bilo H.J., Landman G.W., Van Hateren K.J., Kleefstra N., Hallan S.I., Ballew S.H., Chen J., Kwak L., Surapaneni A., Parving H.-H., Rodby R.A., Rohde R.D., Lewis J.B., Lewis E., Perrone R.D., Abebe K.Z., Hou F.F., Xie D., Hunsicker L.G., Imai E., Kobayashi F., Makino H., Remuzzi G., Ruggenenti P., Eckardt K.-U., and Gudmundsdottir H.
Abstract: Background: Change in albuminuria as a surrogate endpoint for progression of chronic kidney disease is strongly supported by biological plausibility, but empirical evidence to support its validity in epidemiological studies is lacking. We aimed to assess the consistency of the association between change in albuminuria and risk of end-stage kidney disease in a large individual participant-level meta-analysis of observational studies. Method(s): In this meta-analysis, we collected individual-level data from eligible cohorts in the Chronic Kidney Disease Prognosis Consortium (CKD-PC) with data on serum creatinine and change in albuminuria and more than 50 events on outcomes of interest. Cohort data were eligible if participants were aged 18 years or older, they had a repeated measure of albuminuria during an elapsed period of 8 months to 4 years, subsequent end-stage kidney disease or mortality follow-up data, and the cohort was active during this consortium phase. We extracted participant-level data and quantified percentage change in albuminuria, measured as change in urine albumin-to-creatinine ratio (ACR) or urine protein-to-creatinine ratio (PCR), during baseline periods of 1, 2, and 3 years. Our primary outcome of interest was development of end-stage kidney disease after a baseline period of 2 years. We defined an end-stage kidney disease event as initiation of kidney replacement therapy. We quantified associations of percentage change in albuminuria with subsequent end-stage kidney disease using Cox regression in each cohort, followed by random-effects meta-analysis. We further adjusted for regression dilution to account for imprecision in the estimation of albuminuria at the participant level. We did multiple subgroup analyses, and also repeated our analyses using participant-level data from 14 clinical trials, including nine clinical trials not in CKD-PC. Finding(s): Between July, 2015, and June, 2018, we transferred and analysed data from 28 cohorts in the C
Published: 2019

11. Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017

Author: James, S.L. Abate, D. Abate, K.H. Abay, S.M. Abbafati, C. Abbasi, N. Abbastabar, H. Abd-Allah, F. Abdela, J. Abdelalim, A. Abdollahpour, I. Abdulkader, R.S. Abebe, Z. Abera, S.F. Abil, O.Z. Abraha, H.N. Abu-Raddad, L.J. Abu-Rmeileh, N.M.E. Accrombessi, M.M.K. Acharya, D. Acharya, P. Ackerman, I.N. Adamu, A.A. Adebayo, O.M. Adekanmbi, V. Adetokunboh, O.O. Adib, M.G. Adsuar, J.C. Afanvi, K.A. Afarideh, M. Afshin, A. Agarwal, G. Agesa, K.M. Aggarwal, R. Aghayan, S.A. Agrawal, S. Ahmadi, A. Ahmadi, M. Ahmadieh, H. Ahmed, M.B. Aichour, A.N. Aichour, I. Aichour, M.T.E. Akinyemiju, T. Akseer, N. Al-Aly, Z. Al-Eyadhy, A. Al-Mekhlafi, H.M. Al-Raddadi, R.M. Alahdab, F. Alam, K. Alam, T. Alashi, A. Alavian, S.M. Alene, K.A. Alijanzadeh, M. Alizadeh-Navaei, R. Aljunid, S.M. Alkerwi, A. Alla, F. Allebeck, P. Alouani, M.M.L. Altirkawi, K. Alvis-Guzman, N. Amare, A.T. Aminde, L.N. Ammar, W. Amoako, Y.A. Anber, N.H. Andrei, C.L. Androudi, S. Animut, M.D. Anjomshoa, M. Ansha, M.G. Antonio, C.A.T. Anwari, P. Arabloo, J. Arauz, A. Aremu, O. Ariani, F. Armoon, B. Ärnlöv, J. Arora, A. Artaman, A. Aryal, K.K. Asayesh, H. Asghar, R.J. Ataro, Z. Atre, S.R. Ausloos, M. Avila-Burgos, L. Avokpaho, E.F.G.A. Awasthi, A. Ayala Quintanilla, B.P. Ayer, R. Azzopardi, P.S. Babazadeh, A. Badali, H. Badawi, A. Bali, A.G. Ballesteros, K.E. Ballew, S.H. Banach, M. Banoub, J.A.M. Banstola, A. Barac, A. Barboza, M.A. Barker-Collo, S.L. Bärnighausen, T.W. Barrero, L.H. Baune, B.T. Bazargan-Hejazi, S. Bedi, N. Beghi, E. Behzadifar, M. Behzadifar, M. Béjot, Y. Belachew, A.B. Belay, Y.A. Bell, M.L. Bello, A.K. Bensenor, I.M. Bernabe, E. Bernstein, R.S. Beuran, M. Beyranvand, T. Bhala, N. Bhattarai, S. Bhaumik, S. Bhutta, Z.A. Biadgo, B. Bijani, A. Bikbov, B. Bilano, V. Bililign, N. Bin Sayeed, M.S. Bisanzio, D. Blacker, B.F. Blyth, F.M. Bou-Orm, I.R. Boufous, S. Bourne, R. Brady, O.J. Brainin, M. Brant, L.C. Brazinova, A. Breitborde, N.J.K. Brenner, H. Briant, P.S. Briggs, A.M. Briko, A.N. Britton, G. Brugha, T. Buchbinder, R. Busse, R. Butt, Z.A. Cahuana-Hurtado, L. Cano, J. Cárdenas, R. Carrero, J.J. Carter, A. Carvalho, F. Castañeda-Orjuela, C.A. Castillo Rivas, J. Castro, F. Catalá-López, F. Cercy, K.M. Cerin, E. Chaiah, Y. Chang, A.R. Chang, H.-Y. Chang, J.-C. Charlson, F.J. Chattopadhyay, A. Chattu, V.K. Chaturvedi, P. Chiang, P.P.-C. Chin, K.L. Chitheer, A. Choi, J.-Y.J. Chowdhury, R. Christensen, H. Christopher, D.J. Cicuttini, F.M. Ciobanu, L.G. Cirillo, M. Claro, R.M. Collado-Mateo, D. Cooper, C. Coresh, J. Cortesi, P.A. Cortinovis, M. Costa, M. Cousin, E. Criqui, M.H. Cromwell, E.A. Cross, M. Crump, J.A. Dadi, A.F. Dandona, L. Dandona, R. Dargan, P.I. Daryani, A. Das Gupta, R. Das Neves, J. Dasa, T.T. Davey, G. Davis, A.C. Davitoiu, D.V. De Courten, B. De La Hoz, F.P. De Leo, D. De Neve, J.-W. Degefa, M.G. Degenhardt, L. Deiparine, S. Dellavalle, R.P. Demoz, G.T. Deribe, K. Dervenis, N. Des Jarlais, D.C. Dessie, G.A. Dey, S. Dharmaratne, S.D. Dinberu, M.T. Dirac, M.A. Djalalinia, S. Doan, L. Dokova, K. Doku, D.T. Dorsey, E.R. Doyle, K.E. Driscoll, T.R. Dubey, M. Dubljanin, E. Duken, E.E. Duncan, B.B. Duraes, A.R. Ebrahimi, H. Ebrahimpour, S. Echko, M.M. Edvardsson, D. Effiong, A. Ehrlich, J.R. El Bcheraoui, C. El Sayed Zaki, M. El-Khatib, Z. Elkout, H. Elyazar, I.R.F. Enayati, A. Endries, A.Y. Er, B. Erskine, H.E. Eshrati, B. Eskandarieh, S. Esteghamati, A. Esteghamati, S. Fakhim, H. Fallah Omrani, V. Faramarzi, M. Fareed, M. Farhadi, F. Farid, T.A. Farinha, C.S.E. Farioli, A. Faro, A. Farvid, M.S. Farzadfar, F. Feigin, V.L. Fentahun, N. Fereshtehnejad, S.-M. Fernandes, E. Fernandes, J.C. Ferrari, A.J. Feyissa, G.T. Filip, I. Fischer, F. Fitzmaurice, C. Foigt, N.A. Foreman, K.J. Fox, J. Frank, T.D. Fukumoto, T. Fullman, N. Fürst, T. Furtado, J.M. Futran, N.D. Gall, S. Ganji, M. Gankpe, F.G. Garcia-Basteiro, A.L. Gardner, W.M. Gebre, A.K. Gebremedhin, A.T. Gebremichael, T.G. Gelano, T.F. Geleijnse, J.M. Genova-Maleras, R. Geramo, Y.C.D. Gething, P.W. Gezae, K.E. Ghadiri, K. Ghasemi Falavarjani, K. Ghasemi-Kasman, M. Ghimire, M. Ghosh, R. Ghoshal, A.G. Giampaoli, S. Gill, P.S. Gill, T.K. Ginawi, I.A. Giussani, G. Gnedovskaya, E.V. Goldberg, E.M. Goli, S. Gómez-Dantés, H. Gona, P.N. Gopalani, S.V. Gorman, T.M. Goulart, A.C. Goulart, B.N.G. Grada, A. Grams, M.E. Grosso, G. Gugnani, H.C. Guo, Y. Gupta, P.C. Gupta, R. Gupta, R. Gupta, T. Gyawali, B. Haagsma, J.A. Hachinski, V. Hafezi-Nejad, N. Haghparast Bidgoli, H. Hagos, T.B. Hailu, G.B. Haj-Mirzaian, A. Haj-Mirzaian, A. Hamadeh, R.R. Hamidi, S. Handal, A.J. Hankey, G.J. Hao, Y. Harb, H.L. Harikrishnan, S. Haro, J.M. Hasan, M. Hassankhani, H. Hassen, H.Y. Havmoeller, R. Hawley, C.N. Hay, R.J. Hay, S.I. Hedayatizadeh-Omran, A. Heibati, B. Hendrie, D. Henok, A. Herteliu, C. Heydarpour, S. Hibstu, D.T. Hoang, H.T. Hoek, H.W. Hoffman, H.J. Hole, M.K. Homaie Rad, E. Hoogar, P. Hosgood, H.D. Hosseini, S.M. Hosseinzadeh, M. Hostiuc, M. Hostiuc, S. Hotez, P.J. Hoy, D.G. Hsairi, M. Htet, A.S. Hu, G. Huang, J.J. Huynh, C.K. Iburg, K.M. Ikeda, C.T. Ileanu, B. Ilesanmi, O.S. Iqbal, U. Irvani, S.S.N. Irvine, C.M.S. Mohammed, S. Islam, S. Islami, F. Jacobsen, K.H. Jahangiry, L. Jahanmehr, N. Jain, S.K. Jakovljevic, M. Javanbakht, M. Jayatilleke, A.U. Jeemon, P. Jha, R.P. Jha, V. Ji, J.S. Johnson, C.O. Jonas, J.B. Jozwiak, J.J. Jungari, S.B. Jürisson, M. Kabir, Z. Kadel, R. Kahsay, A. Kalani, R. Kanchan, T. Karami, M. Karami Matin, B. Karch, A. Karema, C. Karimi, N. Karimi, S.M. Kasaeian, A. Kassa, D.H. Kassa, G.M. Kassa, T.D. Kassebaum, N.J. Katikireddi, S.V. Kawakami, N. Kazemi Karyani, A. Keighobadi, M.M. Keiyoro, P.N. Kemmer, L. Kemp, G.R. Kengne, A.P. Keren, A. Khader, Y.S. Khafaei, B. Khafaie, M.A. Khajavi, A. Khalil, I.A. Khan, E.A. Khan, M.S. Khan, M.A. Khang, Y.-H. Khazaei, M. Khoja, A.T. Khosravi, A. Khosravi, M.H. Kiadaliri, A.A. Kiirithio, D.N. Kim, C.-I. Kim, D. Kim, P. Kim, Y.-E. Kim, Y.J. Kimokoti, R.W. Kinfu, Y. Kisa, A. Kissimova-Skarbek, K. Kivimäki, M. Knudsen, A.K.S. Kocarnik, J.M. Kochhar, S. Kokubo, Y. Kolola, T. Kopec, J.A. Kosen, S. Kotsakis, G.A. Koul, P.A. Koyanagi, A. Kravchenko, M.A. Krishan, K. Krohn, K.J. Kuate Defo, B. Kucuk Bicer, B. Kumar, G.A. Kumar, M. Kyu, H.H. Lad, D.P. Lad, S.D. Lafranconi, A. Lalloo, R. Lallukka, T. Lami, F.H. Lansingh, V.C. Latifi, A. Lau, K.M.-M. Lazarus, J.V. Leasher, J.L. Ledesma, J.R. Lee, P.H. Leigh, J. Leung, J. Levi, M. Lewycka, S. Li, S. Li, Y. Liao, Y. Liben, M.L. Lim, L.-L. Lim, S.S. Liu, S. Lodha, R. Looker, K.J. Lopez, A.D. Lorkowski, S. Lotufo, P.A. Low, N. Lozano, R. Lucas, T.C.D. Lucchesi, L.R. Lunevicius, R. Lyons, R.A. Ma, S. Macarayan, E.R.K. Mackay, M.T. Madotto, F. Magdy Abd El Razek, H. Magdy Abd El Razek, M. Maghavani, D.P. Mahotra, N.B. Mai, H.T. Majdan, M. Majdzadeh, R. Majeed, A. Malekzadeh, R. Malta, D.C. Mamun, A.A. Manda, A.-L. Manguerra, H. Manhertz, T. Mansournia, M.A. Mantovani, L.G. Mapoma, C.C. Maravilla, J.C. Marcenes, W. Marks, A. Martins-Melo, F.R. Martopullo, I. März, W. Marzan, M.B. Mashamba-Thompson, T.P. Massenburg, B.B. Mathur, M.R. Matsushita, K. Maulik, P.K. Mazidi, M. McAlinden, C. McGrath, J.J. McKee, M. Mehndiratta, M.M. Mehrotra, R. Mehta, K.M. Mehta, V. Mejia-Rodriguez, F. Mekonen, T. Melese, A. Melku, M. Meltzer, M. Memiah, P.T.N. Memish, Z.A. Mendoza, W. Mengistu, D.T. Mengistu, G. Mensah, G.A. Mereta, S.T. Meretoja, A. Meretoja, T.J. Mestrovic, T. Mezerji, N.M.G. Miazgowski, B. Miazgowski, T. Millear, A.I. Miller, T.R. Miltz, B. Mini, G.K. Mirarefin, M. Mirrakhimov, E.M. Misganaw, A.T. Mitchell, P.B. Mitiku, H. Moazen, B. Mohajer, B. Mohammad, K.A. Mohammadifard, N. Mohammadnia-Afrouzi, M. Mohammed, M.A. Mohammed, S. Mohebi, F. Moitra, M. Mokdad, A.H. Molokhia, M. Monasta, L. Moodley, Y. Moosazadeh, M. Moradi, G. Moradi-Lakeh, M. Moradinazar, M. Moraga, P. Morawska, L. Moreno Velásquez, I. Morgado-Da-Costa, J. Morrison, S.D. Moschos, M.M. Mousavi, S.M. Mruts, K.B. Muche, A.A. Muchie, K.F. Mueller, U.O. Muhammed, O.S. Mukhopadhyay, S. Muller, K. Mumford, J.E. Murhekar, M. Musa, J. Musa, K.I. Mustafa, G. Nabhan, A.F. Nagata, C. Naghavi, M. Naheed, A. Nahvijou, A. Naik, G. Naik, N. Najafi, F. Naldi, L. Nam, H.S. Nangia, V. Nansseu, J.R. Nascimento, B.R. Natarajan, G. Neamati, N. Negoi, I. Negoi, R.I. Neupane, S. Newton, C.R.J. Ngunjiri, J.W. Nguyen, A.Q. Nguyen, H.T. Nguyen, H.L.T. Nguyen, H.T. Nguyen, L.H. Nguyen, M. Nguyen, N.B. Nguyen, S.H. Nichols, E. Ningrum, D.N.A. Nixon, M.R. Nolutshungu, N. Nomura, S. Norheim, O.F. Noroozi, M. Norrving, B. Noubiap, J.J. Nouri, H.R. Nourollahpour Shiadeh, M. Nowroozi, M.R. Nsoesie, E.O. Nyasulu, P.S. Odell, C.M. Ofori-Asenso, R. Ogbo, F.A. Oh, I.-H. Oladimeji, O. Olagunju, A.T. Olagunju, T.O. Olivares, P.R. Olsen, H.E. Olusanya, B.O. Ong, K.L. Ong, S.K. Oren, E. Ortiz, A. Ota, E. Otstavnov, S.S. øverland, S. Owolabi, M.O. Mahesh, P.A. Pacella, R. Pakpour, A.H. Pana, A. Panda-Jonas, S. Parisi, A. Park, E.-K. Parry, C.D.H. Patel, S. Pati, S. Patil, S.T. Patle, A. Patton, G.C. Paturi, V.R. Paulson, K.R. Pearce, N. Pereira, D.M. Perico, N. Pesudovs, K. Pham, H.Q. Phillips, M.R. Pigott, D.M. Pillay, J.D. Piradov, M.A. Pirsaheb, M. Pishgar, F. Plana-Ripoll, O. Plass, D. Polinder, S. Popova, S. Postma, M.J. Pourshams, A. Poustchi, H. Prabhakaran, D. Prakash, S. Prakash, V. Purcell, C.A. Purwar, M.B. Qorbani, M. Quistberg, D.A. Radfar, A. Rafay, A. Rafiei, A. Rahim, F. Rahimi, K. Rahimi-Movaghar, A. Rahimi-Movaghar, V. Rahman, M. Ur Rahman, M.H. Rahman, M.A. Rahman, S.U. Rai, R.K. Rajati, F. Ram, U. Ranjan, P. Ranta, A. Rao, P.C. Rawaf, D.L. Rawaf, S. Reddy, K.S. Reiner, R.C. Reinig, N. Reitsma, M.B. Remuzzi, G. Renzaho, A.M.N. Resnikoff, S. Rezaei, S. Rezai, M.S. Ribeiro, A.L.P. Robinson, S.R. Roever, L. Ronfani, L. Roshandel, G. Rostami, A. Roth, G.A. Roy, A. Rubagotti, E. Sachdev, P.S. Sadat, N. Saddik, B. Sadeghi, E. Saeedi Moghaddam, S. Safari, H. Safari, Y. Safari-Faramani, R. Safdarian, M. Safi, S. Safiri, S. Sagar, R. Sahebkar, A. Sahraian, M.A. Sajadi, H.S. Salam, N. Salama, J.S. Salamati, P. Saleem, K. Saleem, Z. Salimi, Y. Salomon, J.A. Salvi, S.S. Salz, I. Samy, A.M. Sanabria, J. Sang, Y. Santomauro, D.F. Santos, I.S. Santos, J.V. Santric Milicevic, M.M. Sao Jose, B.P. Sardana, M. Sarker, A.R. Sarrafzadegan, N. Sartorius, B. Sarvi, S. Sathian, B. Satpathy, M. Sawant, A.R. Sawhney, M. Saxena, S. Saylan, M. Schaeffner, E. Schmidt, M.I. Schneider, I.J.C. Schöttker, B. Schwebel, D.C. Schwendicke, F. Scott, J.G. Sekerija, M. Sepanlou, S.G. Serván-Mori, E. Seyedmousavi, S. Shabaninejad, H. Shafieesabet, A. Shahbazi, M. Shaheen, A.A. Shaikh, M.A. Shams-Beyranvand, M. Shamsi, M. Shamsizadeh, M. Sharafi, H. Sharafi, K. Sharif, M. Sharif-Alhoseini, M. Sharma, M. Sharma, R. She, J. Sheikh, A. Shi, P. Shibuya, K. Shigematsu, M. Shiri, R. Shirkoohi, R. Shishani, K. Shiue, I. Shokraneh, F. Shoman, H. Shrime, M.G. Si, S. Siabani, S. Siddiqi, T.J. Sigfusdottir, I.D. Sigurvinsdottir, R. Silva, J.P. Silveira, D.G.A. Singam, N.S.V. Singh, J.A. Singh, N.P. Singh, V. Sinha, D.N. Skiadaresi, E. Slepak, E.L.N. Sliwa, K. Smith, D.L. Smith, M. Soares Filho, A.M. Sobaih, B.H. Sobhani, S. Sobngwi, E. Soneji, S.S. Soofi, M. Soosaraei, M. Sorensen, R.J.D. Soriano, J.B. Soyiri, I.N. Sposato, L.A. Sreeramareddy, C.T. Srinivasan, V. Stanaway, J.D. Stein, D.J. Steiner, C. Steiner, T.J. Stokes, M.A. Stovner, L.J. Subart, M.L. Sudaryanto, A. Sufiyan, M.B. Sunguya, B.F. Sur, P.J. Sutradhar, I. Sykes, B.L. Sylte, D.O. Tabarés-Seisdedos, R. Tadakamadla, S.K. Tadesse, B.T. Tandon, N. Tassew, S.G. Tavakkoli, M. Taveira, N. Taylor, H.R. Tehrani-Banihashemi, A. Tekalign, T.G. Tekelemedhin, S.W. Tekle, M.G. Temesgen, H. Temsah, M.-H. Temsah, O. Terkawi, A.S. Teweldemedhin, M. Thankappan, K.R. Thomas, N. Tilahun, B. To, Q.G. Tonelli, M. Topor-Madry, R. Topouzis, F. Torre, A.E. Tortajada-Girbés, M. Touvier, M. Tovani-Palone, M.R. Towbin, J.A. Tran, B.X. Tran, K.B. Troeger, C.E. Truelsen, T.C. Tsilimbaris, M.K. Tsoi, D. Tudor Car, L. Tuzcu, E.M. Ukwaja, K.N. Ullah, I. Undurraga, E.A. Unutzer, J. Updike, R.L. Usman, M.S. Uthman, O.A. Vaduganathan, M. Vaezi, A. Valdez, P.R. Varughese, S. Vasankari, T.J. Venketasubramanian, N. Villafaina, S. Violante, F.S. Vladimirov, S.K. Vlassov, V. Vollset, S.E. Vosoughi, K. Vujcic, I.S. Wagnew, F.S. Waheed, Y. Waller, S.G. Wang, Y. Wang, Y.-P. Weiderpass, E. Weintraub, R.G. Weiss, D.J. Weldegebreal, F. Weldegwergs, K.G. Werdecker, A. West, T.E. Whiteford, H.A. Widecka, J. Wijeratne, T. Wilner, L.B. Wilson, S. Winkler, A.S. Wiyeh, A.B. Wiysonge, C.S. Wolfe, C.D.A. Woolf, A.D. Wu, S. Wu, Y.-C. Wyper, G.M.A. Xavier, D. Xu, G. Yadgir, S. Yadollahpour, A. Yahyazadeh Jabbari, S.H. Yamada, T. Yan, L.L. Yano, Y. Yaseri, M. Yasin, Y.J. Yeshaneh, A. Yimer, E.M. Yip, P. Yisma, E. Yonemoto, N. Yoon, S.-J. Yotebieng, M. Younis, M.Z. Yousefifard, M. Yu, C. Zadnik, V. Zaidi, Z. Zaman, S.B. Zamani, M. Zare, Z. Zeleke, A.J. Zenebe, Z.M. Zhang, K. Zhao, Z. Zhou, M. Zodpey, S. Zucker, I. Vos, T. Murray, C.J.L. GBD 2017 Disease Injury Incidence Prevalence Collaborators
Abstract: Background: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 2017. Previous GBD studies have shown how the decline of mortality rates from 1990 to 2016 has led to an increase in life expectancy, an ageing global population, and an expansion of the non-fatal burden of disease and injury. These studies have also shown how a substantial portion of the world's population experiences non-fatal health loss with considerable heterogeneity among different causes, locations, ages, and sexes. Ongoing objectives of the GBD study include increasing the level of estimation detail, improving analytical strategies, and increasing the amount of high-quality data. Methods: We estimated incidence and prevalence for 354 diseases and injuries and 3484 sequelae. We used an updated and extensive body of literature studies, survey data, surveillance data, inpatient admission records, outpatient visit records, and health insurance claims, and additionally used results from cause of death models to inform estimates using a total of 68 781 data sources. Newly available clinical data from India, Iran, Japan, Jordan, Nepal, China, Brazil, Norway, and Italy were incorporated, as well as updated claims data from the USA and new claims data from Taiwan (province of China) and Singapore. We used DisMod-MR 2.1, a Bayesian meta-regression tool, as the main method of estimation, ensuring consistency between rates of incidence, prevalence, remission, and cause of death for each condition. YLDs were estimated as the product of a prevalence estimate and a disability weight for health states of each mutually exclusive sequela, adjusted for comorbidity. We updated the Socio-demographic Index (SDI), a summary development indicator of income per capita, years of schooling, and total fertility rate. Additionally, we calculated differences between male and female YLDs to identify divergent trends across sexes. GBD 2017 complies with the Guidelines for Accurate and Transparent Health Estimates Reporting. Findings: Globally, for females, the causes with the greatest age-standardised prevalence were oral disorders, headache disorders, and haemoglobinopathies and haemolytic anaemias in both 1990 and 2017. For males, the causes with the greatest age-standardised prevalence were oral disorders, headache disorders, and tuberculosis including latent tuberculosis infection in both 1990 and 2017. In terms of YLDs, low back pain, headache disorders, and dietary iron deficiency were the leading Level 3 causes of YLD counts in 1990, whereas low back pain, headache disorders, and depressive disorders were the leading causes in 2017 for both sexes combined. All-cause age-standardised YLD rates decreased by 3·9% (95% uncertainty interval [UI] 3·1-4·6) from 1990 to 2017; however, the all-age YLD rate increased by 7·2% (6·0-8·4) while the total sum of global YLDs increased from 562 million (421-723) to 853 million (642-1100). The increases for males and females were similar, with increases in all-age YLD rates of 7·9% (6·6-9·2) for males and 6·5% (5·4-7·7) for females. We found significant differences between males and females in terms of age-standardised prevalence estimates for multiple causes. The causes with the greatest relative differences between sexes in 2017 included substance use disorders (3018 cases [95% UI 2782-3252] per 100 000 in males vs 1400 [1279-1524] per 100 000 in females), transport injuries (3322 [3082-3583] vs 2336 [2154-2535]), and self-harm and interpersonal violence (3265 [2943-3630] vs 5643 [5057-6302]). Interpretation: Global all-cause age-standardised YLD rates have improved only slightly over a period spanning nearly three decades. However, the magnitude of the non-fatal disease burden has expanded globally, with increasing numbers of people who have a wide spectrum of conditions. A subset of conditions has remained globally pervasive since 1990, whereas other conditions have displayed more dynamic trends, with different ages, sexes, and geographies across the globe experiencing varying burdens and trends of health loss. This study emphasises how global improvements in premature mortality for select conditions have led to older populations with complex and potentially expensive diseases, yet also highlights global achievements in certain domains of disease and injury. Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
Published: 2018

12. Multicenter Phase II Study of Stereotactic Ablative Radiotherapy for Hepatocellular Carcinoma ≤ 5 cm (KROG 12-02)

Author: Jang, W.I., primary, Kim, M.S., additional, Yang, K.M., additional, Yoo, H.J., additional, Kim, E., additional, Paik, E.K., additional, Choi, C.W., additional, Chang, A.R., additional, Park, Y.H., additional, Kim, E.S., additional, Jo, S., additional, Kim, W.C., additional, Park, J.H., additional, Bae, S.H., additional, and Park, H.J., additional
Published: 2019
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13. EP-1542 Long-term results and PSA kinetics after robotic SBRT for prostate cancer

Author: Park, Y., primary, Park, H.J., additional, Jang, W.I., additional, Jeong, B.K., additional, Kim, H., additional, and Chang, A.R., additional
Published: 2019
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14. Association of metformin use with risk of lactic acidosis across the range of kidney function: A community-based cohort study.

Author: Lazarus B., Sang Y., Alexander G.C., Secora A., Inker L.A., Coresh J., Chang A.R., Grams M.E., Shin J.-I., Wu A., Lazarus B., Sang Y., Alexander G.C., Secora A., Inker L.A., Coresh J., Chang A.R., Grams M.E., Shin J.-I., and Wu A.
Abstract: Importance: Approximately 1 million patients in the United States with type 2 diabetes mellitus and mild-to-moderate kidney disease do not receive guideline-directed therapy with metformin. This may reflect uncertainty regarding the risk of acidosis in patients with chronic kidney disease. Objective(s): To quantify the association between metformin use and hospitalization with acidosis across the range of estimated glomerular filtration rate (eGFR), accounting for change in eGFR stage over time. Design, Setting, and Participant(s): Community-based cohort of 75 413 patients with diabetes in Geisinger Health System, with time-dependent assessment of eGFR stage from January 2004 until January 2017. Results were replicated in 67 578 new metformin users and 14 439 new sulfonylurea users from 2010 to 2015, sourced from 350 private US health systems. Exposures: Metformin use. Main Outcomes and Measures: Hospitalization with acidosis (International Classification of Diseases, Ninth Revision, Clinical Modification code of 276.2). Result(s): In the primary cohort (n = 75 413), mean (SD) patient age was 60.4 (15.5) years, and 51%(n = 38 480) of the participants were female. There were 2335 hospitalizations with acidosis over a median follow-up of 5.7 years (interquartile range, 2.5-9.9 years). Compared with alternative diabetes management, time-dependent metformin use was not associated with incident acidosis overall (adjusted hazard ratio [HR], 0.98; 95%CI, 0.89-1.08) or in patients with eGFR 45 to 59 mL/min/1.73m2 (adjusted HR, 1.16; 95%CI, 0.95-1.41) and eGFR 30 to 44 mL/min/1.73m2 (adjusted HR, 1.09; 95%CI, 0.83-1.44). On the other hand, metformin use was associated with an increased risk of acidosis at eGFR less than 30 mL/min/1.73m2 (adjusted HR, 2.07; 95%CI, 1.33-3.22). Results were consistent when new metformin users were compared with new sulfonylurea users (adjusted HR for eGFR 30-44 mL/min/1.73m2, 0.77; 95%CI, 0.29-2.05), in a propensity-matched cohort (adjusted HR
Published: 2018

15. Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017.

Author: She J., Thankappan K.R., Thomas N., Tilahun B., To Q.G., Tonelli M., Topor-Madry R., Topouzis F., Torre A.E., Tortajada-Girbes M., Touvier M., Tovani-Palone M.R., Towbin J.A., Tran B.X., Tran K.B., Troeger C.E., Truelsen T.C., Tsilimbaris M.K., Tsoi D., Tudor Car L., Tuzcu E.M., Ukwaja K.N., Ullah I., Undurraga E.A., Unutzer J., Updike R.L., Usman M.S., Uthman O.A., Vaduganathan M., Vaezi A., Valdez P.R., Varughese S., Vasankari T.J., Venketasubramanian N., Villafaina S., Violante F.S., Vladimirov S.K., Vlassov V., Vollset S.E., Vosoughi K., Vujcic I.S., Wagnew F.S., Waheed Y., Waller S.G., Wang Y., Wang Y.-P., Weiderpass E., Weintraub R.G., Weiss D.J., Weldegebreal F., Weldegwergs K.G., Werdecker A., West T.E., Whiteford H.A., Widecka J., Wijeratne T., Wilner L.B., Wilson S., Winkler A.S., Wiyeh A.B., Wiysonge C.S., Wolfe C.D.A., Woolf A.D., Wu S., Wu Y.-C., Wyper G.M.A., Xavier D., Xu G., Yadgir S., Yadollahpour A., Yahyazadeh Jabbari S.H., Yamada T., Yan L.L., Yano Y., Yaseri M., Yasin Y.J., Yeshaneh A., Yimer E.M., Yip P., Yisma E., Yonemoto N., Yoon S.-J., Yotebieng M., Younis M.Z., Yousefifard M., Yu C., Zadnik V., Zaidi Z., Zaman S.B., Zamani M., Zare Z., Zeleke A.J., Zenebe Z.M., Zhang K., Zhao Z., Zhou M., Zodpey S., Zucker I., Vos T., Murray C.J.L., De Courten B., Fox J., James S.L., Abate D., Abate K.H., Abay S.M., Abbafati C., Abbasi N., Abbastabar H., Abd-Allah F., Abdela J., Abdelalim A., Abdollahpour I., Abdulkader R.S., Abebe Z., Abera S.F., Abil O.Z., Abraha H.N., Abu-Raddad L.J., Abu-Rmeileh N.M.E., Accrombessi M.M.K., Acharya D., Acharya P., Ackerman I.N., Adamu A.A., Adebayo O.M., Adekanmbi V., Adetokunboh O.O., Adib M.G., Adsuar J.C., Afanvi K.A., Afarideh M., Afshin A., Agarwal G., Agesa K.M., Aggarwal R., Aghayan S.A., Agrawal S., Ahmadi A., Ahmadi M., Ahmadieh H., Ahmed M.B., Aichour A.N., Aichour I., Aichour M.T.E., Akinyemiju T., Akseer N., Al-Aly Z., Al-Eyadhy A., Al-Mekhlafi H.M., Al-Raddadi R.M., Alahdab F., Alam K., Alam 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S., Bhutta Z.A., Biadgo B., Bijani A., Bikbov B., Bilano V., Bililign N., Bin Sayeed M.S., Bisanzio D., Blacker B.F., Blyth F.M., Bou-Orm I.R., Boufous S., Bourne R., Brady O.J., Brainin M., Brant L.C., Brazinova A., Breitborde N.J.K., Brenner H., Briant P.S., Briggs A.M., Briko A.N., Britton G., Brugha T., Buchbinder R., Busse R., Butt Z.A., Cahuana-Hurtado L., Cano J., Cardenas R., Carrero J.J., Carter A., Carvalho F., Castaneda-Orjuela C.A., Castillo Rivas J., Castro F., Catala-Lopez F., Cercy K.M., Cerin E., Chaiah Y., Chang A.R., Chang H.-Y., Chang J.-C., Charlson F.J., Chattopadhyay A., Chattu V.K., Chaturvedi P., Chiang P.P.-C., Chin K.L., Chitheer A., Choi J.-Y.J., Chowdhury R., Christensen H., Christopher D.J., Cicuttini F.M., Ciobanu L.G., Cirillo M., Claro R.M., Collado-Mateo D., Cooper C., Coresh J., Cortesi P.A., Cortinovis M., Costa M., Cousin E., Criqui M.H., Cromwell E.A., Cross M., Crump J.A., Dadi A.F., Dandona L., Dandona R., Dargan P.I., Daryani A., Das Gupta R., 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K.J., Frank T.D., Fukumoto T., Fullman N., Furst T., Furtado J.M., Futran N.D., Gall S., Ganji M., Gankpe F.G., Garcia-Basteiro A.L., Gardner W.M., Gebre A.K., Gebremedhin A.T., Gebremichael T.G., Gelano T.F., Geleijnse J.M., Genova-Maleras R., Geramo Y.C.D., Gething P.W., Gezae K.E., Ghadiri K., Ghasemi Falavarjani K., Ghasemi-Kasman M., Ghimire M., Ghosh R., Ghoshal A.G., Giampaoli S., Gill P.S., Gill T.K., Ginawi I.A., Giussani G., Gnedovskaya E.V., Goldberg E.M., Goli S., Gomez-Dantes H., Gona P.N., Gopalani S.V., Gorman T.M., Goulart A.C., Goulart B.N.G., Grada A., Grams M.E., Grosso G., Gugnani H.C., Guo Y., Gupta P.C., Gupta R., Gupta T., Gyawali B., Haagsma J.A., Hachinski V., Hafezi-Nejad N., Haghparast Bidgoli H., Hagos T.B., Hailu G.B., Haj-Mirzaian A., Hamadeh R.R., Hamidi S., Handal A.J., Hankey G.J., Hao Y., Harb H.L., Harikrishnan S., Haro J.M., Hasan M., Hassankhani H., Hassen H.Y., Havmoeller R., Hawley C.N., Hay R.J., Hay S.I., Hedayatizadeh-Omran A., Heibati B., 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Oren E., Ortiz A., Ota E., Otstavnov S.S., overland S., Owolabi M.O., Mahesh P.A., Pacella R., Pakpour A.H., Pana A., Panda-Jonas S., Parisi A., Park E.-K., Parry C.D.H., Patel S., Pati S., Patil S.T., Patle A., Patton G.C., Paturi V.R., Paulson K.R., Pearce N., Pereira D.M., Perico N., Pesudovs K., Pham H.Q., Phillips M.R., Pigott D.M., Pillay J.D., Piradov M.A., Pirsaheb M., Pishgar F., Plana-Ripoll O., Plass D., Polinder S., Popova S., Postma M.J., Pourshams A., Poustchi H., Prabhakaran D., Prakash S., Prakash V., Purcell C.A., Purwar M.B., Qorbani M., Quistberg D.A., Radfar A., Rafay A., Rafiei A., Rahim F., Rahimi K., Rahimi-Movaghar A., Rahimi-Movaghar V., Rahman M., Ur Rahman M.H., Rahman M.A., Rahman S.U., Rai R.K., Rajati F., Ram U., Ranjan P., Ranta A., Rao P.C., Rawaf D.L., Rawaf S., Reddy K.S., Reiner R.C., Reinig N., Reitsma M.B., Remuzzi G., Renzaho A.M.N., Resnikoff S., Rezaei S., Rezai M.S., Ribeiro A.L.P., Robinson S.R., Roever L., Ronfani L., Roshandel G., Rostami A., Roth G.A., Roy A., Rubagotti E., Sachdev P.S., Sadat N., Saddik B., Sadeghi E., Saeedi Moghaddam S., Safari H., Safari Y., Safari-Faramani R., Safdarian M., Safi S., Safiri S., Sagar R., Sahebkar A., Sahraian M.A., Sajadi H.S., Salam N., Salama J.S., Salamati P., Saleem K., Saleem Z., Salimi Y., Salomon J.A., Salvi S.S., Salz I., Samy A.M., Sanabria J., Sang Y., Santomauro D.F., Santos I.S., Santos J.V., Santric Milicevic M.M., Sao Jose B.P., Sardana M., Sarker A.R., Sarrafzadegan N., Sartorius B., Sarvi S., Sathian B., Satpathy M., Sawant A.R., Sawhney M., Saxena S., Saylan M., Schaeffner E., Schmidt M.I., Schneider I.J.C., Schottker B., Schwebel D.C., Schwendicke F., Scott J.G., Sekerija M., Sepanlou S.G., Servan-Mori E., Seyedmousavi S., Shabaninejad H., Shafieesabet A., Shahbazi M., Shaheen A.A., Shaikh M.A., Shams-Beyranvand M., Shamsi M., Shamsizadeh M., Sharafi H., Sharafi K., Sharif M., Sharif-Alhoseini M., Sharma M., Sharma R., Sheikh A., Shi P., Shibuya K., Shigematsu M., 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H.W., Hoffman H.J., Hole M.K., Homaie Rad E., Hoogar P., Hosgood H.D., Hosseini S.M., Hosseinzadeh M., Hostiuc M., Hostiuc S., Hotez P.J., Hoy D.G., Hsairi M., Htet A.S., Hu G., Huang J.J., Huynh C.K., Iburg K.M., Ikeda C.T., Ileanu B., Ilesanmi O.S., Iqbal U., Irvani S.S.N., Irvine C.M.S., Islam S., Islami F., Jacobsen K.H., Jahangiry L., Jahanmehr N., Jain S.K., Jakovljevic M., Javanbakht M., Jayatilleke A.U., Jeemon P., Jha R.P., Jha V., Ji J.S., Johnson C.O., Jonas J.B., Jozwiak J.J., Jungari S.B., Jurisson M., Kabir Z., Kadel R., Kahsay A., Kalani R., Kanchan T., Karami M., Karami Matin B., Karch A., Karema C., Karimi N., Karimi S.M., Kasaeian A., Kassa D.H., Kassa G.M., Kassa T.D., Kassebaum N.J., Katikireddi S.V., Kawakami N., Kazemi Karyani A., Keighobadi M.M., Keiyoro P.N., Kemmer L., Kemp G.R., Kengne A.P., Keren A., Khader Y.S., Khafaei B., Khafaie M.A., Khajavi A., Khalil I.A., Khan E.A., Khan M.S., Khan M.A., Khang Y.-H., Khazaei M., Khoja A.T., Khosravi A., Khosravi M.H., Kiadaliri A.A., Kiirithio D.N., Kim C.-I., Kim D., Kim P., Kim Y.-E., Kim Y.J., Kimokoti R.W., Kinfu Y., Kisa A., Kissimova-Skarbek K., Kivimaki M., Knudsen A.K.S., Kocarnik J.M., Kochhar S., Kokubo Y., Kolola T., Kopec J.A., Kosen S., Kotsakis G.A., Koul P.A., Koyanagi A., Kravchenko M.A., Krishan K., Krohn K.J., Kuate Defo B., Kucuk Bicer B., Kumar G.A., Kumar M., Kyu H.H., Lad D.P., Lad S.D., Lafranconi A., Lalloo R., Lallukka T., Lami F.H., Lansingh V.C., Latifi A., Lau K.M.-M., Lazarus J.V., Leasher J.L., Ledesma J.R., Lee P.H., Leigh J., Leung J., Levi M., Lewycka S., Li S., Li Y., Liao Y., Liben M.L., Lim L.-L., Lim S.S., Liu S., Lodha R., Looker K.J., Lopez A.D., Lorkowski S., Lotufo P.A., Low N., Lozano R., Lucas T.C.D., Lucchesi L.R., Lunevicius R., Lyons R.A., Ma S., Macarayan E.R.K., Mackay M.T., Madotto F., Magdy Abd El Razek H., Magdy Abd El Razek M., Maghavani D.P., Mahotra N.B., Mai H.T., Majdan M., Majdzadeh R., Majeed A., Malekzadeh R., Malta D.C., Mamun A.A., Manda 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P.A., Pacella R., Pakpour A.H., Pana A., Panda-Jonas S., Parisi A., Park E.-K., Parry C.D.H., Patel S., Pati S., Patil S.T., Patle A., Patton G.C., Paturi V.R., Paulson K.R., Pearce N., Pereira D.M., Perico N., Pesudovs K., Pham H.Q., Phillips M.R., Pigott D.M., Pillay J.D., Piradov M.A., Pirsaheb M., Pishgar F., Plana-Ripoll O., Plass D., Polinder S., Popova S., Postma M.J., Pourshams A., Poustchi H., Prabhakaran D., Prakash S., Prakash V., Purcell C.A., Purwar M.B., Qorbani M., Quistberg D.A., Radfar A., Rafay A., Rafiei A., Rahim F., Rahimi K., Rahimi-Movaghar A., Rahimi-Movaghar V., Rahman M., Ur Rahman M.H., Rahman M.A., Rahman S.U., Rai R.K., Rajati F., Ram U., Ranjan P., Ranta A., Rao P.C., Rawaf D.L., Rawaf S., Reddy K.S., Reiner R.C., Reinig N., Reitsma M.B., Remuzzi G., Renzaho A.M.N., Resnikoff S., Rezaei S., Rezai M.S., Ribeiro A.L.P., Robinson S.R., Roever L., Ronfani L., Roshandel G., Rostami A., Roth G.A., Roy A., Rubagotti E., Sachdev P.S., Sadat N., Saddik B., Sadeghi E., Saeedi Moghaddam S., Safari H., Safari Y., Safari-Faramani R., Safdarian M., Safi S., Safiri S., Sagar R., Sahebkar A., Sahraian M.A., Sajadi H.S., Salam N., Salama J.S., Salamati P., Saleem K., Saleem Z., Salimi Y., Salomon J.A., Salvi S.S., Salz I., Samy A.M., Sanabria J., Sang Y., Santomauro D.F., Santos I.S., Santos J.V., Santric Milicevic M.M., Sao Jose B.P., Sardana M., Sarker A.R., Sarrafzadegan N., Sartorius B., Sarvi S., Sathian B., Satpathy M., Sawant A.R., Sawhney M., Saxena S., Saylan M., Schaeffner E., Schmidt M.I., Schneider I.J.C., Schottker B., Schwebel D.C., Schwendicke F., Scott J.G., Sekerija M., Sepanlou S.G., Servan-Mori E., Seyedmousavi S., Shabaninejad H., Shafieesabet A., Shahbazi M., Shaheen A.A., Shaikh M.A., Shams-Beyranvand M., Shamsi M., Shamsizadeh M., Sharafi H., Sharafi K., Sharif M., Sharif-Alhoseini M., Sharma M., Sharma R., Sheikh A., Shi P., Shibuya K., Shigematsu M., Shiri R., Shirkoohi R., Shishani K., Shiue I., Shokraneh F., Shoman H., Shrime M.G., Si S., Siabani S., Siddiqi T.J., Sigfusdottir I.D., Sigurvinsdottir R., Silva J.P., Silveira D.G.A., Singam N.S.V., Singh J.A., Singh N.P., Singh V., Sinha D.N., Skiadaresi E., Slepak E.L.N., Sliwa K., Smith D.L., Smith M., Soares Filho A.M., Sobaih B.H., Sobhani S., Sobngwi E., Soneji S.S., Soofi M., Soosaraei M., Sorensen R.J.D., Soriano J.B., Soyiri I.N., Sposato L.A., Sreeramareddy C.T., Srinivasan V., Stanaway J.D., Stein D.J., Steiner C., Steiner T.J., Stokes M.A., Stovner L.J., Subart M.L., Sudaryanto A., Sufiyan M.B., Sunguya B.F., Sur P.J., Sutradhar I., Sykes B.L., Sylte D.O., Tabares-Seisdedos R., Tadakamadla S.K., Tadesse B.T., Tandon N., Tassew S.G., Tavakkoli M., Taveira N., Taylor H.R., Tehrani-Banihashemi A., Tekalign T.G., Tekelemedhin S.W., Tekle M.G., Temesgen H., Temsah M.-H., Temsah O., Terkawi A.S., and Teweldemedhin M.
Abstract: Background: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 2017. Previous GBD studies have shown how the decline of mortality rates from 1990 to 2016 has led to an increase in life expectancy, an ageing global population, and an expansion of the non-fatal burden of disease and injury. These studies have also shown how a substantial portion of the world's population experiences non-fatal health loss with considerable heterogeneity among different causes, locations, ages, and sexes. Ongoing objectives of the GBD study include increasing the level of estimation detail, improving analytical strategies, and increasing the amount of high-quality data. Method(s): We estimated incidence and prevalence for 354 diseases and injuries and 3484 sequelae. We used an updated and extensive body of literature studies, survey data, surveillance data, inpatient admission records, outpatient visit records, and health insurance claims, and additionally used results from cause of death models to inform estimates using a total of 68 781 data sources. Newly available clinical data from India, Iran, Japan, Jordan, Nepal, China, Brazil, Norway, and Italy were incorporated, as well as updated claims data from the USA and new claims data from Taiwan (province of China) and Singapore. We used DisMod-MR 2.1, a Bayesian meta-regression tool, as the main method of estimation, ensuring consistency between rates of incidence, prevalence, remission, and cause of death for each condition. YLDs were estimated as the product of a prevalence estimate and a disability weight for health states of each mutually exclusive sequela, adjusted for comorbidity. We updated the Socio-demographic Index (SDI), a summary development indicator of income per capita, years of schooling, and total fertility rate. Additionally, we
Published: 2018

16. An International Radiosurgery Consortium Survey for Gynecological Stereotactic Ablative Radiation Therapy

Author: Leung, E.W., primary, Gladwish, A., additional, Sahgal, A., additional, Lo, S.S., additional, Kunos, C.A., additional, Lanciano, R.M., additional, Mantz, C.A., additional, Guckenberger, M., additional, Zagar, T.M., additional, Mayr, N.A., additional, Chang, A.R., additional, Jorcano, S., additional, Biswas, T., additional, Pontoriero, A., additional, and Albuquerque, K.V., additional
Published: 2017
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17. A multi-institutional study of bladder-preserving therapy for stage □ to □ bladder cancer: A Korean radiation oncology group study (KROG 14-16)

Author: Byun, S.J., primary, Kim, J.H., additional, Park, W., additional, Cho, K.H., additional, Cho, J.H., additional, Chang, A.R., additional, and Kang, K.M., additional
Published: 2016
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18. A Multicenter Phase II Study of Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma

Author: Jang, W.I., primary, Kim, M.S., additional, Seo, Y.S., additional, Kang, J.K., additional, Paik, E.K., additional, Choi, C.W., additional, Chang, A.R., additional, Park, Y.H., additional, Kim, E.S., additional, Jo, S., additional, Kim, W., additional, Bae, S.H., additional, and Park, H.J., additional
Published: 2016
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19. 465P Predictors of rib fracture after lung stereotactic ablative radiotherapy

Author: Park, Y., primary, Kim, H.J., additional, and Chang, A.R., additional
Published: 2015
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20. Rapid diagnosis of Penicillium marneffei infection by fine needle aspiration cytology

Author: Lim, D., Lee, Y.-S., and Chang, A.R.
Subjects: Mycoses -- Diagnosis, Biopsy, Needle -- Usage, Fungi, Pathogenic -- Identification and classification, Health
Published: 2006

21. EP-1266: Impact of metformin on outcome in patients with hepatocellular carcinoma with radiotherapy

Author: Jang, W.I., primary, Kim, M.S., additional, Cho, C.K., additional, Yoo, H.J., additional, Seo, Y.S., additional, Kang, J.K., additional, Kim, K.B., additional, Lee, D.H., additional, Kay, C.S., additional, and Chang, A.R., additional
Published: 2014
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22. P126 - A multi-institutional study of bladder-preserving therapy for stage □ to □ bladder cancer: A Korean radiation oncology group study (KROG 14-16)

Author: Byun, S.J., Kim, J.H., Park, W., Cho, K.H., Cho, J.H., Chang, A.R., and Kang, K.M.
Published: 2016
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23. Dose responses in a normoxic polymethacrylic acid gel dosimeter using optimal CT scanning parameters

Author: Cho, K.H., primary, Cho, S.J., additional, Lee, S., additional, Lee, S.H., additional, Min, C.K., additional, Kim, Y.H., additional, Moon, S.K., additional, Kim, E.S., additional, Chang, A.R., additional, and Kwon, S.I., additional
Published: 2012
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24. P.127 Regional lymph node involvement, patternsof regional recurrences, and radiation dose response relationship in squamous cell carcinoma of oropharynx

Author: Wu, H.-G., primary, Chang, A.R., additional, Park, W., additional, Ahn, Y.C., additional, Oh, Y.T., additional, and Park, C.I., additional
Published: 2005
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25. P.130 Patterns of regional recurrences and optimal radiation dose for oropharynx cancer

Author: Wu, H.-G., primary, Chang, A.R., additional, Park, W., additional, Ahn, Y.C., additional, Oh, Y.T., additional, and Park, C.I., additional
Published: 2005
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26. In vitro uptake of bromodeoxyuridine by human nasopharyngeal carcinoma (NPC) and its relation to clinical findings

Author: Chan, A.T.C., primary, Ho, S., additional, Teo, P.M.L., additional, Law, V., additional, Tjong, J., additional, Yu, P., additional, Chang, A.R., additional, Kwan, W.H., additional, Leung, W.T., additional, and Johnson, P.J., additional
Published: 1996
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27. Assessment of proliferating cell nuclear antigen in nasopharyngeal carcinoma tissue and its relation to clinical findings

Author: Chan, A.T.C., Ho, S., Teo, P.M.L., Tjong, J., Choi, J., Lee, W.Y., Chang, A.R., Kwan, W.H., Leung, W.T., and Johnson, P.J.
Published: 1997
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28. Rapid induction of gastric ulceration in guinea pigs by sequential exposure to a barrier breaker and indomethacin

Author: Maclaurin, Brian P. and Chang, A.R.
Abstract: In short term experiments under halothane anesthesia, guinea pig total gastric pouches were initially and terminally exposed to 0.1M HCI for 30min. During an intervening 50-min test period, the gastric mucosa was exposed at pH 7.3, either to a barrier breaker (lysolecithin or diluted bile or sodium taurocholate) or to phosphate buffered saline (PBS) for half of the period, followed by exposure to indomethacin or further PBS for the second half of the test period. Scoring of mucosal damage was assessed from coded photographs and histological slides and by measurement of the transmucosal potential difference
Published: 1983
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29. Test and Teach Number Twenty-One Part 2

Author: Chang, A.R., primary
Published: 1980
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30. Test and Teach Number Twenty-One Part 1

Author: Chang, A.R., primary
Published: 1980
Full Text: View/download PDF

31. Test and Teach Number Seventeen Part 1

Author: Chang, A.R., primary
Published: 1979
Full Text: View/download PDF

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31 results on '"Chang A.R."'

1. Major cardiovascular events and subsequent risk of kidney failure with replacement therapy: a CKD Prognosis Consortium study

2. Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019

3. Conversion of urine protein-creatinine ratio or urine dipstick protein to urine albumin-creatinine ratio for use in chronic kidney disease screening and prognosis: An individual participant-based meta-analysis.

4. Conversion of Urine Protein-Creatinine Ratio or Urine Dipstick Protein to Urine Albumin-Creatinine Ratio for Use in Chronic Kidney Disease Screening and Prognosis : An Individual Participant-Based Meta-analysis

5. Five insights from the Global Burden of Disease Study 2019.

6. Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019.

7. PO-1188: Optimal radiotherapy strategy as risk-group in non-metastatic prostate cancer patients (KROG 18-15)

8. Adiposity and risk of decline in glomerular filtration rate: meta-analysis of individual participant data in a global consortium

9. Evaluating Glomerular Filtration Rate Slope as a Surrogate End Point for ESKD in Clinical Trials: An Individual Participant Meta-Analysis of Observational Data

10. Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies.

11. Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017

12. Multicenter Phase II Study of Stereotactic Ablative Radiotherapy for Hepatocellular Carcinoma ≤ 5 cm (KROG 12-02)

13. EP-1542 Long-term results and PSA kinetics after robotic SBRT for prostate cancer

14. Association of metformin use with risk of lactic acidosis across the range of kidney function: A community-based cohort study.

15. Global, regional, and national incidence, prevalence, and years lived with disability for 354 Diseases and Injuries for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017.

16. An International Radiosurgery Consortium Survey for Gynecological Stereotactic Ablative Radiation Therapy

17. A multi-institutional study of bladder-preserving therapy for stage □ to □ bladder cancer: A Korean radiation oncology group study (KROG 14-16)

18. A Multicenter Phase II Study of Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma

19. 465P Predictors of rib fracture after lung stereotactic ablative radiotherapy

20. Rapid diagnosis of Penicillium marneffei infection by fine needle aspiration cytology

21. EP-1266: Impact of metformin on outcome in patients with hepatocellular carcinoma with radiotherapy

22. P126 - A multi-institutional study of bladder-preserving therapy for stage □ to □ bladder cancer: A Korean radiation oncology group study (KROG 14-16)

23. Dose responses in a normoxic polymethacrylic acid gel dosimeter using optimal CT scanning parameters

24. P.127 Regional lymph node involvement, patternsof regional recurrences, and radiation dose response relationship in squamous cell carcinoma of oropharynx

25. P.130 Patterns of regional recurrences and optimal radiation dose for oropharynx cancer

26. In vitro uptake of bromodeoxyuridine by human nasopharyngeal carcinoma (NPC) and its relation to clinical findings

27. Assessment of proliferating cell nuclear antigen in nasopharyngeal carcinoma tissue and its relation to clinical findings

28. Rapid induction of gastric ulceration in guinea pigs by sequential exposure to a barrier breaker and indomethacin

29. Test and Teach Number Twenty-One Part 2

30. Test and Teach Number Twenty-One Part 1

31. Test and Teach Number Seventeen Part 1

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31 results on '"Chang A.R."'

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