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13. An on-line electronic check system with mutual authentication

Author

Chang, Chin-Chen, Chang, Shih-Chang, and Lee, Jung-San

Subjects
Computers, Electronics, Engineering and manufacturing industries
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.compeleceng.2009.02.007 Byline: Chin-Chen Chang, Shih-Chang Chang, Jung-San Lee Keywords: E-check; Mutual authentication; One-way hash function; Blind signature; RSA cryptosystems Abstract: Electronic check (e-check) is an important component of electronic commerce. It was first proposed by Chaum in 1988. Till now, engineers have provided many improvements to enhance the security and functionality of the e-check system. The face value of a check and the identification of a payee, however, have to be determined previously in these improved versions. This results in the inflexibility of the system. In this paper, we aim to propose a novel e-check mechanism which allows a payer attaching the face value and the information of a payee to an e-check when dealing with a transaction. The security of this novel system is based on several cryptographic techniques including the secure one-way hash function, blind signature, and RSA cryptosystems. Author Affiliation: Department of Information Engineering and Computer Science, Feng Chia University, 100 Wenhwa Rd., Seatwen, Taichung 40724, Taiwan, ROC Article History: Received 6 August 2007; Revised 18 October 2008; Accepted 6 February 2009

Published
2009

14. A gut butyrate-producing bacterium Butyricicoccus pullicaecorum regulates short-chain fatty acid transporter and receptor to reduce the progression of 1,2-dimethylhydrazine-associated colorectal cancer

Author

Chang, Shih-Chang, Shen, Ming-Hung, Liu, Chih-Yi, Pu, Chi-Ming, Hu, Je-Ming, and Huang, Chi-Jung

Subjects
1,2-dimethylhydrazine, colorectal cancer, Articles, butyrate, Butyricicoccus pullicaecorum, digestive system diseases
Abstract

Gut microbes influence tumor development and progression in the intestines and may provide a novel paradigm for the treatment of colorectal cancer (CRC). Gut dysbiosis may be associated with the development and progression of CRC. Identifying the interactions between the colonic tract and gut microbiota may provide novel information relevant to CRC prevention. The present study examined the effects of butyrate-producing Butyricicoccus pullicaecorum (B. pullicaecorum) on mice with 1,2-dimethylhydrazine (DMH)-induced CRC and the microbial metabolite of B. pullicaecorum on CRC cells. Immunohistochemical staining of the mouse colon tissues and reverse transcription PCR of CRC cells were used to determine the protein and mRNA expression levels of the short-chain fatty acid (SCFA) transporter solute carrier family 5 member 8 (SLC5A8) and G-protein-coupled receptor 43 (GPR43). In CRC-bearing mice fed B. pullicaecorum, DMH-induced CRC regressed, body weight increased and serum carcinoembryonic antigen levels decreased. Notably, SLC5A8 and GPR43 were diffusely and moderately to strongly expressed in the neoplastic epithelial cells and underlying muscularis propria in the colons of the mice. In conclusion, administration of B. pullicaecorum or its metabolites improved the clinical outcome of CRC by activating the SCFA transporter and/or receptor. These results indicated that B. pullicaecorum was a probiotic with anti-CRC potential.

Published
2020

17. Controlling Ni2+ from the Surface to the Bulk by a New Cathode Electrolyte Interphase Formation on a Ni-Rich Layered Cathode in High-Safe and High-Energy-Density Lithium-Ion Batteries

Author

Yeh, Nan-Hung, primary, Wang, Fu-Ming, additional, Khotimah, Chusnul, additional, Wang, Xing-Chun, additional, Lin, Yi-Wen, additional, Chang, Shih-Chang, additional, Hsu, Chun-Chuan, additional, Chang, Yung-Jen, additional, Tiong, Lester, additional, Liu, Chia-Hao, additional, Lu, Ying-Rui, additional, Liao, Yen-Fa, additional, Chang, Chung-Kai, additional, Haw, Shu-Chih, additional, Pao, Chih-Wen, additional, Chen, Jeng-Lung, additional, Chen, Chi-Liang, additional, Lee, Jyh-Fu, additional, Chan, Ting-Shan, additional, Sheu, Hwo-Shuenn, additional, Chen, Jin-Ming, additional, Ramar, Alagar, additional, and Su, Chia-Hung, additional

Published
2021
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21. The Risk Factors Affecting Survival in Colorectal Cancer in Taiwan

Author

LEE, Chao-Hsien, CHENG, Shu-Chen, TUNG, Hong-Yi, CHANG, Shih-Chang, CHING, Ching-Yun, and WU, Shu-Fen

Subjects
Risk factors, Survival, lcsh:Public aspects of medicine, Original Article, lcsh:RA1-1270, Colorectal cancer
Abstract

Background: Colorectal cancer is one of the most common malignancies in developed countries. The incidence of colorectal cancer (CRC) in Taiwan is rising. We aimed to determine the five-yr survival rate of patients diagnosed with CRC and determine factors affecting survival. Methods: All patients were identified from the Taiwan Cancer Data Base of the Medical Center Hospital in North Taiwan from 2007 to 2013. Data were collected using medical records and the cancer database. In all, 869 patients with CRC were included. Survival analysis was performed using Kaplan-Meier curves, and differences between the curves were analyzed using the log-rank test. Cox proportional hazards regression models were used to analyze survival by each variable. Results: The five-yr survival rate and the mean survival time after cancer diagnosis were 68.7% and 71.27±1.27 months. Perineural nerve invasion, distant metastasis, age, pathological differentiation grade, obstruction and regional lymph node metastasis were found to be independent predictors of the survival and prognosis of patients with CRC. Conclusion: Perineural nerve invasion was an important factor related to the survival of CRC patients. Thus, the earlier detection of CRC might help improve survival.

Published
2018

22. Perianal eccrine adenocarcinoma

Author

Lee Henry, Leung Tsz-Ho, and Chang Shih-Chang

Subjects
Surgery, RD1-811, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background Eccrine carcinoma is a quite rare malignant tumor that typically arises from a normal sweat gland and that features a rather high recurrence rate subsequent to simple excision. Given its rather poor response to adjuvant therapy, wide excision of the lesion with tumor-free margins may offer a reasonable chance for long-term control of this neoplasm. Case presentation Herein, we report on an unusual case of perianal eccrine carcinoma, initially presenting as a perianal abscess. Conclusion Even though eccrine carcinomas would appear to be rare, when dealing with recurrent skin tumors or recurrent perianal fistulas, the possibility of eccrine carcinoma should be considered by consulting clinicians.

Published
2007
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23. Controlling Ni2+ from the Surface to the Bulk by a New Cathode Electrolyte Interphase Formation on a Ni-Rich Layered Cathode in High-Safe and High-Energy-Density Lithium-Ion Batteries.

Author

Yeh, Nan-Hung, Wang, Fu-Ming, Khotimah, Chusnul, Wang, Xing-Chun, Lin, Yi-Wen, Chang, Shih-Chang, Hsu, Chun-Chuan, Chang, Yung-Jen, Tiong, Lester, Liu, Chia-Hao, Lu, Ying-Rui, Liao, Yen-Fa, Chang, Chung-Kai, Haw, Shu-Chih, Pao, Chih-Wen, Chen, Jeng-Lung, Chen, Chi-Liang, Lee, Jyh-Fu, Chan, Ting-Shan, and Sheu, Hwo-Shuenn

Published
2021
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24. Comparison of risk factors between colon cancer and rectum cancer in a single medical center hospital, Taiwan.

Author

Chao-Hsien Lee, Peng-Lin Tseng, Hong-Yi Tung, Shu-Chen Cheng, Ching-Yun Ching, Shih-Chang Chang, Shu-Fen Wuq, Lee, Chao-Hsien, Tseng, Peng-Lin, Tung, Hong-Yi, Cheng, Shu-Chen, Ching, Ching-Yun, Chang, Shih-Chang, and Wu, Shu-Fen

Subjects
COLON cancer, PROPORTIONAL hazards models, MEDICAL centers, LOG-rank test, RECTAL cancer
Abstract

Introduction: Colorectal cancer (CRC) is rapidly increasing in developed countries. In Taiwan, the incidence rate of CRC has increased during the past decade, but the 5-year survival has remained at approximately 63%. In this study, we sought to determine the 5-year survival rate of patients diagnosed with colon and rectum cancer and to determine factors affecting survival.Material and Methods: All patients from the Taiwan Cancer Database of the medical center hospital in North Taiwan between 2007 and 2013 were identified. Survival analysis was performed using Kaplan-Meier curves, and differences between the curves were analyzed using the log-rank test. Cox proportional hazards regression models were used to analyze survival by each variable.Results: A total of 869 patients were included: 554 (63.8%) patients had colon cancer and 315 (36.2%) had rectum cancer. The mean survival time was 71.27 ±1.27 months (colon group: 71.90 ±1.58 months; rectum group: 67.88 ±1.95 months). There was no significant difference (p = 0.493) between patients who had colon or rectum cancer. The forward stepwise Cox regression analysis results indicated that perineural invasion, distant metastasis, age, pathological differentiation grade, and obstruction were statistically significant for patients who had CRC, colon cancer or rectum cancer.Conclusions: The long-term survival from CRC, colon cancer and rectum cancer remains promising, as 68.66%, 69.11% and 67.90% of patients are alive 5 years after being diagnosed, respectively. Perineural invasion was found to be an important factor related to the survival of patients who have CRC. Thus, early detection of CRC may help improve survival. [ABSTRACT FROM AUTHOR]

Published
2020
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26. Stem cell culture on polyvinyl alcohol hydrogels having different elasticity and immobilized with ECM-derived oligopeptides

Author

Muduli, Saradaprasan, Chen, Li-Hua, Li, Meng-Pei, Heish, Zhao-wen, Liu, Cheng-Hui, Kumar, Suresh, Alarfaj, Abdullah A., Munusamy, Murugan A., Benelli, Giovanni, Murugan, Kadarkarai, Wang, Han-Chow, Chen, Da-Chung, Hsu, Shih-Tien, Chang, Shih-Chang, Higuchi, Akon, Muduli, Saradaprasan, Chen, Li-Hua, Li, Meng-Pei, Heish, Zhao-wen, Liu, Cheng-Hui, Kumar, Suresh, Alarfaj, Abdullah A., Munusamy, Murugan A., Benelli, Giovanni, Murugan, Kadarkarai, Wang, Han-Chow, Chen, Da-Chung, Hsu, Shih-Tien, Chang, Shih-Chang, and Higuchi, Akon

Abstract

The physical characteristics of cell culture materials, such as their elasticity, affect stem cell fate with respect to cell proliferation and differentiation. We systematically investigated the morphologies and characteristics of several stem cell types, including human amniotic-derived stem cells, human hematopoietic stem cells, human induced pluripotent stem (iPS) cells, and embryonic stem (ES) cells on poly(vinyl alcohol) (PVA) hydrogels immobilized with and without extracellular matrix-derived oligopeptide. Human ES cells did not adhere well to soft PVA hydrogels immobilized with oligovitronectin, whereas they did adhere well to PVA hydrogel dishes with elasticities greater than 15 kPa. These results indicate that biomaterials such as PVA hydrogels should be designed to possess minimum elasticity to facilitate human ES cell attachment. PVA hydrogels immobilized with and without extracellular matrix-derived oligopeptides are excellent candidates of cell culture biomaterials for investigations into how cell culture biomaterial elasticity affects stem cell culture and differentiation.

Published
2017

27. Controlling Ni2+from the Surface to the Bulk by a New Cathode Electrolyte Interphase Formation on a Ni-Rich Layered Cathode in High-Safe and High-Energy-Density Lithium-Ion Batteries

Author

Yeh, Nan-Hung, Wang, Fu-Ming, Khotimah, Chusnul, Wang, Xing-Chun, Lin, Yi-Wen, Chang, Shih-Chang, Hsu, Chun-Chuan, Chang, Yung-Jen, Tiong, Lester, Liu, Chia-Hao, Lu, Ying-Rui, Liao, Yen-Fa, Chang, Chung-Kai, Haw, Shu-Chih, Pao, Chih-Wen, Chen, Jeng-Lung, Chen, Chi-Liang, Lee, Jyh-Fu, Chan, Ting-Shan, Sheu, Hwo-Shuenn, Chen, Jin-Ming, Ramar, Alagar, and Su, Chia-Hung

Abstract

Ni-rich high-energy-density lithium ion batteries pose great risks to safety due to internal short circuits and overcharging; they also have poor performance because of cation mixing and disordering problems. For Ni-rich layered cathodes, these factors cause gas evolution, the formation of side products, and life cycle decay. In this study, a new cathode electrolyte interphase (CEI) for Ni2+self-oxidation is developed. By using a branched oligomer electrode additive, the new CEI is formed and prevents the reduction of Ni3+to Ni2+on the surface of Ni-rich layered cathode; this maintains the layered structure and the cation mixing during cycling. In addition, this new CEI ensures the stability of Ni4+that is formed at 100% state of charge in the crystal lattice at high temperature (660 K); this prevents the rock-salt formation and the over-reduction of Ni4+to Ni2+. These findings are obtained using in situ X-ray absorption spectroscopy, operando X-ray diffraction, operando gas chromatography–mass spectroscopy, and X-ray photoelectron spectroscopy. Transmission electron microscopy reveals that the new CEI has an elliptical shape on the material surface, which is approximately 100 nm in length and 50 nm in width, and covers selected particle surfaces. After the new CEI was formed on the surface, the Ni2+self-oxidation gradually affects from the surface to the bulk of the material. It found that the bond energy and bond length of the Ni–O are stabilized, which dramatically inhibit gas evolution. The new CEI is successfully applied in a Ni-rich layered compound, and the 18650- and the punch-type full cells are fabricated. The energy density of the designed cells is up to 300 Wh/kg. Internal short circuit and overcharging safety tests are passed when using the standard regulations of commercial evaluation. This new CEI technology is ready and planned for future applications in electric vehicle and energy storage.

Published
2021
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28. Robust Benzimidazole-Based Electrolyte Overcomes High-Voltage and High-Temperature Applications in 5 V Class Lithium Ion Batteries

Author

Wang, Fu-Ming, primary, Pradanawati, Sylvia Ayu, additional, Yeh, Nan-Hung, additional, Chang, Shih-Chang, additional, Yang, Ya-Tang, additional, Huang, Shih-Han, additional, Lin, Ping-Ling, additional, Lee, Jyh-Fu, additional, Sheu, Hwo-Shuenn, additional, Lu, Meng-Lin, additional, Chang, Chung-Kai, additional, Ramar, Alagar, additional, and Su, Chia-Hung, additional

Published
2017
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29. Stem cell culture on polyvinyl alcohol hydrogels having different elasticity and immobilized with ECM-derived oligopeptides

Author

Muduli, Saradaprasan, primary, Chen, Li-Hua, additional, Li, Meng-Pei, additional, Heish, Zhao-wen, additional, Liu, Cheng-Hui, additional, Kumar, Suresh, additional, Alarfaj, Abdullah A., additional, Munusamy, Murugan A., additional, Benelli, Giovanni, additional, Murugan, Kadarkarai, additional, Wang, Han-Chow, additional, Chen, Da-Chung, additional, Hsu, Shih-Tien, additional, Chang, Shih-Chang, additional, and Higuchi, Akon, additional

Published
2016
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32. Long-term xeno-free culture of human pluripotent stem cells on hydrogels with optimal elasticity

Author

Higuchi, Akon, primary, Kao, Shih-Hsuan, additional, Ling, Qing-Dong, additional, Chen, Yen-Ming, additional, Li, Hsing-Fen, additional, Alarfaj, Abdullah A., additional, Munusamy, Murugan A., additional, Murugan, Kadarkarai, additional, Chang, Shih-Chang, additional, Lee, Hsin-Chung, additional, Hsu, Shih-Tien, additional, Kumar, S. Suresh, additional, and Umezawa, Akihiro, additional

Published
2015
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41. Low Temperature Poly-Si TFT Characteristics in the Overlapped Area of Excimer Laser Long-Axis Scans

Author

ELECTRONIC RESEARCH AND SERVICE ORGANIZATION/INDUSTRIAL TECHNOLOGY RESEARCH INST HSINCHU (TAIWAN), Chang, Shih-Chang, Shih, Chu-Jung, Lu, I-Min, Wu, I-Wei, ELECTRONIC RESEARCH AND SERVICE ORGANIZATION/INDUSTRIAL TECHNOLOGY RESEARCH INST HSINCHU (TAIWAN), Chang, Shih-Chang, Shih, Chu-Jung, Lu, I-Min, and Wu, I-Wei

Abstract

We have investigated the laser crystallized LT poly-Si TFT characteristics in the overlapped area of excimer laser scans in the long axis direction. Continuous TFTs located at the edges of single scan and overlaps of two scans were used. Different laser energy densities were dual-scanned to study the characteristics of the TFTs in overlapped area. It was found that the laser with higher energy density dominates the TFT characteristics and their characteristics in the overlapped area can be as good as those in the non-overlapped area Based on these results large uniform LT poly-Si panel can be fabricated by overlapping the laser scans in the long axis direction., Presented at Display Technologies III, International Optoelectronics Symposium, Taipei, Taiwan, 26-27 Jul 2000. Pub. in Proceedings of SPIE, v4079 p43-46, 2000. ISSN 0277-786X. This article is from ADA398270 Display Technologies III Held in Taipei, Taiwan on 26-27 July 2000

Published
2000

42. The Characteristics of Single-Pulse Excimer Laser Beam Profile on the Low Temperature Poly-Si TFTs

Author

ELECTRONIC RESEARCH AND SERVICE ORGANIZATION/INDUSTRIAL TECHNOLOGY RESEARCH INST HSINCHU (TAIWAN), Shih, Chu-Jung, Wang, Li-Ming, Chang, Shih-Chang, Lu, I-Min, Wu, I-Wei, ELECTRONIC RESEARCH AND SERVICE ORGANIZATION/INDUSTRIAL TECHNOLOGY RESEARCH INST HSINCHU (TAIWAN), Shih, Chu-Jung, Wang, Li-Ming, Chang, Shih-Chang, Lu, I-Min, and Wu, I-Wei

Abstract

Laser crystallization has been the most promising technology to manufacture low temperature poly-silicon (LTPS) thin film transistors (TFTs), since LTPS technology can make LCD panels with integrated drivers. Higher mobility and lower leakage current than the solid-phase crystallization (SPC) counterparts can be obtained by laser crystallization. I excimer lasers emit in the UV region with a short pulse duration (lO^3Ons), and high temperature can be developed in the Si-surface region, causing melting, without appreciative heating (4OO degrees C) with the glass substrate. 2 Laser processes should provide uniform and stable laser beam profiles to obtain uniform distribution of electrical characteristics of TFTs. In this study, the effects of laser beam profiles were investigated on the crystallization of poly-Si films. "One Pulse" laser crystallized poly-Si was analyzed by SEM and alpha-step to distinguish the effects of non-uniform laser beam profiles. Surface smoothness of poly-Si films with various laser-overlapping ratios was also measured to investigate the effects of laser beam profiles. Then the relationships of TFT characteristics and laser overlapping ratios will be discussed., Presented at Display Technologies III, International Optoelectronics Symposium, Taipei, Taiwan, 26-27 Jul 2000. Pub. in Proceedings of SPIE, v4079 p47-50, 2000. ISSN 0277-786X. This article is from ADA398270 Display Technologies III Held in Taipei, Taiwan on 26-27 July 2000

Published
2000

50. P-9: Ion-Doping Process Using a Hard Gate Mask in Low-Temperature Poly-Si TFT Fabrication

Author

Chiang Dien-Shen, Tsai Yaw-Ming, Lee Ryan, Cheng-Hsun Tsai, and Chang Shih-Chang

Subjects
Fabrication, Materials science, business.industry, Etching (microfabrication), Thin-film transistor, Doping, Electrical engineering, Optoelectronics, Photoresist, business, NMOS logic, AND gate, PMOS logic
Abstract

A new low-temperature polycrystalline-silicon LTPS process was developed. The doping mask for p-type TFT was compared with PR mask and gate hard mask. The process and design challenge in gate hard mask was compared with the photo resist residues problem encountered in PR mask process. In the gate hard mask technology, the gates of p-type and n-type TFTs are etched in different steps for p-type TFT S/D doping and n-type TFT LDD doping. The results indicate the gate insulator loss and the CD loss due to these different etching steps can be controlled in the same magnitude, and the TFT electrical characteristics of NMOS and PMOS are good enough for pixel and driver applications.

Published
2003
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