Search

Your search keyword '"Chandran, Manju"' showing total 305 results
Start Over Author "Chandran, Manju"
305 results on '"Chandran, Manju"'

2. Evidence-Based Guideline for the management of osteoporosis in men

Author

Fuggle, Nicholas R., Beaudart, Charlotte, Bruyère, Olivier, Abrahamsen, Bo, Al-Daghri, Nasser, Burlet, Nansa, Chandran, Manju, Rosa, Mario M., Cortet, Bernard, Demonceau, Céline, Dere, Willard, Halbout, Philippe, Hiligsmann, Mickaël, Kanis, John A., Kaufman, Jean-Marc, Kurth, Andreas, Lamy, Olivier, Laslop, Andrea, Maggi, Stefania, Matijevic, Radmila, McCloskey, Eugene, Mobasheri, Ali, Prieto Yerro, Maria C., Radermecker, Régis P., Sabico, Shaun, Al-Saleh, Yousef, Silverman, Stuart, Veronese, Nicola, Rizzoli, René, Cooper, Cyrus, Reginster, Jean-Yves, and Harvey, Nicholas C.

Published
2024
Full Text
View/download PDF

4. Update on the clinical use of trabecular bone score (TBS) in the management of osteoporosis: results of an expert group meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), and the International Osteoporosis Foundation (IOF) under the auspices of WHO Collaborating Center for Epidemiology of Musculoskeletal Health and Aging

Author

Shevroja, Enisa, Reginster, Jean-Yves, Lamy, Olivier, Al-Daghri, Nasser, Chandran, Manju, Demoux-Baiada, Anne-Laurence, Kohlmeier, Lynn, Lecart, Marie-Paule, Messina, Daniel, Camargos, Bruno Muzzi, Payer, Juraj, Tuzun, Sansin, Veronese, Nicola, Cooper, Cyrus, McCloskey, Eugene V., and Harvey, Nicholas C.

Published
2023
Full Text
View/download PDF

5. Real-world evidence: new opportunities for osteoporosis research. Recommendations from a Working Group from the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO)

Author

Moon, Rebecca J., Reginster, Jean-Yves, Al-Daghri, Nasser M., Thiyagarajan, Jotheeswaran A., Beaudart, Charlotte, Bruyère, Olivier, Burlet, Nansa, Chandran, Manju, da Silva, Mario Coelho, Conaghan, Philip G., Dere, Willard H., Diez-Perez, Adolfo, Hadji, Peyman, Halbout, Philippe, Hiligsmann, Mickaël, Kanis, John A., McCloskey, Eugene V., Ormarsdottir, Sif, Prieto-Alhambra, Daniel, Radermecker, Régis P., Rizzoli, René, Al-Saleh, Yousef, Silverman, Stuart L., Simon, Lee S., Thomasius, Friederike, van Staa, Tjeerd, Laslop, Andrea, Cooper, Cyrus, and Harvey, Nicholas C.

Published
2023
Full Text
View/download PDF

9. Asia-Pacific consensus on long-term and sequential therapy for osteoporosis

Author

Tai, Ta-Wei, Chen, Hsuan-Yu, Shih, Chien-An, Huang, Chun-Feng, McCloskey, Eugene, Lee, Joon-Kiong, Yeap, Swan Sim, Cheung, Ching-Lung, Charatcharoenwitthaya, Natthinee, Jaisamrarn, Unnop, Kuptniratsaikul, Vilai, Yang, Rong-Sen, Lin, Sung-Yen, Taguchi, Akira, Mori, Satoshi, Li-Yu, Julie, Ang, Seng Bin, Chan, Ding-Cheng, Chan, Wai Sin, Ng, Hou, Chen, Jung-Fu, Tu, Shih-Te, Chuang, Hai-Hua, Chang, Yin-Fan, Chen, Fang-Ping, Tsai, Keh-Sung, Ebeling, Peter R., Marin, Fernando, Nistal Rodríguez, Francisco Javier, Shi, Huipeng, Hwang, Kyu Ri, Kim, Kwang-Kyoun, Chung, Yoon-Sok, Reid, Ian R., Chandran, Manju, Ferrari, Serge, Lewiecki, E Michael, Hew, Fen Lee, Ho-Pham, Lan T., Nguyen, Tuan Van, Nguyen, Van Hy, Lekamwasam, Sarath, Pandey, Dipendra, Bhadada, Sanjay, Chen, Chung-Hwan, Hwang, Jawl-Shan, and Wu, Chih-Hsing

Published
2024
Full Text
View/download PDF

12. Interdisciplinary management of FGF23-related phosphate wasting syndromes: a Consensus Statement on the evaluation, diagnosis and care of patients with X-linked hypophosphataemia

Author

Trombetti, Andrea, Al-Daghri, Nasser, Brandi, Maria Luisa, Cannata-Andía, Jorge B., Cavalier, Etienne, Chandran, Manju, Chaussain, Catherine, Cipullo, Lucia, Cooper, Cyrus, Haffner, Dieter, Harvengt, Pol, Harvey, Nicholas C., Javaid, Muhammad Kassim, Jiwa, Famida, Kanis, John A., Laslop, Andrea, Laurent, Michaël R., Linglart, Agnès, Marques, Andréa, Mindler, Gabriel T., Minisola, Salvatore, Yerro, María Concepción Prieto, Rosa, Mario Miguel, Seefried, Lothar, Vlaskovska, Mila, Zanchetta, María Belén, and Rizzoli, René

Published
2022
Full Text
View/download PDF

21. Comparison of the Osteoporosis Self-Assessment Tool for Asians and the fracture risk assessment tool - FRAX to identify densitometric defined osteoporosis: A discriminatory value analysis in a multi-ethnic female population in Southeast Asia

Author

Chandran, Manju, Chin, Yun Ann, Choo, Kuan Swen, Ang, Wan Chen, Huang, Xiao Feng, Liu, Xiao Ming, Tay, Donovan, Aung, Tin Kyaw Kyaw, Ali, Amin, Thu, Win Pa Pa, Logan, Susan, Yan, Sean Xuexian, Lekamwasam, Sarath, and Hao, Ying

Published
2020
Full Text
View/download PDF

23. Artificial intelligence using deep learning to screen for referable and vision-threatening diabetic retinopathy in Africa: a clinical validation study

Author

Bellemo, Valentina, Lim, Zhan W, Lim, Gilbert, Nguyen, Quang D, Xie, Yuchen, Yip, Michelle Y T, Hamzah, Haslina, Ho, Jinyi, Lee, Xin Q, Hsu, Wynne, Lee, Mong L, Musonda, Lillian, Chandran, Manju, Chipalo-Mutati, Grace, Muma, Mulenga, Tan, Gavin S W, Sivaprasad, Sobha, Menon, Geeta, Wong, Tien Y, and Ting, Daniel S W

Published
2019
Full Text
View/download PDF

30. List of Contributors

Author

Bliuc, Dana, primary, Bogoch, Earl, additional, Center, Jacqueline R., additional, Chan, Ding-Cheng (Derrick), additional, Chandran, Manju, additional, Chang, Lo-Yu, additional, Close, Jacqueline C.T., additional, Elliot-Gibson, Victoria, additional, Endo, Naoto, additional, Ganda, Kirtan, additional, Jain, Ravi, additional, Javaid, Muhammad Kassim, additional, Maalouf, Ghassan, additional, Mitchell, Paul J., additional, Olenginski, Thomas P., additional, Rizkallah, Maroun, additional, Sale, Joanna, additional, Seibel, Markus J., additional, Takahashi, Hideaki E., additional, and Yamamoto, Noriaki, additional

Published
2019
Full Text
View/download PDF

33. Global epidemiology of hip fractures: secular trends in incidence rate, post‐fracture treatment, and all‐cause mortality

Author

Sing, Chor‐Wing, primary, Lin, Tzu‐Chieh, additional, Bartholomew, Sharon, additional, J, Simon Bell, additional, Bennett, Corina, additional, Beyene, Kebede, additional, Bosco‐Levy, Pauline, additional, Bradbury, Brian D, additional, Chan, Amy Hai Yan, additional, Chandran, Manju, additional, Cooper, Cyrus, additional, de Ridder, Maria, additional, Y, Caroline Doyon, additional, Droz‐Perroteau, Cécile, additional, Ganesan, Ganga, additional, Hartikainen, Sirpa, additional, Ilomaki, Jenni, additional, Jeong, Han Eol, additional, Kiel, Douglas P, additional, Kubota, Kiyoshi, additional, Chia‐Cheng Lai, Edward, additional, Lange, Jeff L, additional, Lewiecki, E Michael, additional, Lin, Julian, additional, Liu, Jiannong, additional, Maskell, Joe, additional, de Abreu, Mirhelen Mendes, additional, O'Kelly, James, additional, Ooba, Nobuhiro, additional, Pedersen, Alma B, additional, Prats‐Uribe, Albert, additional, Prieto‐Alhambra, Daniel, additional, Qin, Simon Xiwen, additional, Shin, Ju‐Young, additional, Sørensen, Henrik T, additional, Tan, Kelvin Bryan, additional, Thomas, Tracy, additional, Tolppanen, Anna‐Maija, additional, MC, Katia Verhamme, additional, Wang, Grace Hsin‐Min, additional, Watcharathanakij, Sawaeng, additional, J, Stephen Wood, additional, Cheung, Ching‐Lung, additional, and Wong, Ian CK, additional

Published
2023
Full Text
View/download PDF

34. Global Epidemiology of Hip Fractures:Secular Trends in Incidence Rate, Post-Fracture Treatment, and All-Cause Mortality

Author

Sing, Chor Wing, Lin, Tzu Chieh, Bartholomew, Sharon, Bell, J. Simon, Bennett, Corina, Beyene, Kebede, Bosco-Levy, Pauline, Bradbury, Brian D., Chan, Amy Hai Yan, Chandran, Manju, Cooper, Cyrus, de Ridder, Maria, Doyon, Caroline Y., Droz-Perroteau, Cécile, Ganesan, Ganga, Hartikainen, Sirpa, Ilomaki, Jenni, Jeong, Han Eol, Kiel, Douglas P., Kubota, Kiyoshi, Lai, Edward Chia Cheng, Lange, Jeff L., Lewiecki, E. Michael, Lin, Julian, Liu, Jiannong, Maskell, Joe, de Abreu, Mirhelen Mendes, O'Kelly, James, Ooba, Nobuhiro, Pedersen, Alma B., Prats-Uribe, Albert, Prieto-Alhambra, Daniel, Qin, Simon Xiwen, Shin, Ju Young, Sørensen, Henrik T., Tan, Kelvin Bryan, Thomas, Tracy, Tolppanen, Anna Maija, Verhamme, Katia M.C., Wang, Grace Hsin Min, Watcharathanakij, Sawaeng, Wood, Stephen J., Cheung, Ching Lung, Wong, Ian C.K., Sing, Chor Wing, Lin, Tzu Chieh, Bartholomew, Sharon, Bell, J. Simon, Bennett, Corina, Beyene, Kebede, Bosco-Levy, Pauline, Bradbury, Brian D., Chan, Amy Hai Yan, Chandran, Manju, Cooper, Cyrus, de Ridder, Maria, Doyon, Caroline Y., Droz-Perroteau, Cécile, Ganesan, Ganga, Hartikainen, Sirpa, Ilomaki, Jenni, Jeong, Han Eol, Kiel, Douglas P., Kubota, Kiyoshi, Lai, Edward Chia Cheng, Lange, Jeff L., Lewiecki, E. Michael, Lin, Julian, Liu, Jiannong, Maskell, Joe, de Abreu, Mirhelen Mendes, O'Kelly, James, Ooba, Nobuhiro, Pedersen, Alma B., Prats-Uribe, Albert, Prieto-Alhambra, Daniel, Qin, Simon Xiwen, Shin, Ju Young, Sørensen, Henrik T., Tan, Kelvin Bryan, Thomas, Tracy, Tolppanen, Anna Maija, Verhamme, Katia M.C., Wang, Grace Hsin Min, Watcharathanakij, Sawaeng, Wood, Stephen J., Cheung, Ching Lung, and Wong, Ian C.K.

Abstract

In this international study, we examined the incidence of hip fractures, postfracture treatment, and all-cause mortality following hip fractures, based on demographics, geography, and calendar year. We used patient-level healthcare data from 19 countries and regions to identify patients aged 50 years and older hospitalized with a hip fracture from 2005 to 2018. The age- and sex-standardized incidence rates of hip fractures, post-hip fracture treatment (defined as the proportion of patients receiving anti-osteoporosis medication with various mechanisms of action [bisphosphonates, denosumab, raloxifene, strontium ranelate, or teriparatide] following a hip fracture), and the all-cause mortality rates after hip fractures were estimated using a standardized protocol and common data model. The number of hip fractures in 2050 was projected based on trends in the incidence and estimated future population demographics. In total, 4,115,046 hip fractures were identified from 20 databases. The reported age- and sex-standardized incidence rates of hip fractures ranged from 95.1 (95% confidence interval [CI] 94.8–95.4) in Brazil to 315.9 (95% CI 314.0–317.7) in Denmark per 100,000 population. Incidence rates decreased over the study period in most countries; however, the estimated total annual number of hip fractures nearly doubled from 2018 to 2050. Within 1 year following a hip fracture, post-hip fracture treatment ranged from 11.5% (95% CI 11.1% to 11.9%) in Germany to 50.3% (95% CI 50.0% to 50.7%) in the United Kingdom, and all-cause mortality rates ranged from 14.4% (95% CI 14.0% to 14.8%) in Singapore to 28.3% (95% CI 28.0% to 28.6%) in the United Kingdom. Males had lower use of anti-osteoporosis medication than females, higher rates of all-cause mortality, and a larger increase in the projected number of hip fractures by 2050. Substantial variations exist in the global epidemiology of hip fractures and postfracture outcomes. Our findings inform possible actions to reduc

Published
2023

36. The effect of four loading intravitreal aflibercept injections on macular fluid in treatment-naïve neovascular age-related macular degeneration

Author

Chandra, Shruti, Raimondi, Raffaele, Lim, Alicia, Mohan, Amy, Melmane, Sneha, Menon, Geeta, Chandran, Manju, Sivaprasad, Sobha, Burton, Benjamin J. L., and Kotagiri, Ajay

Abstract

Purpose: To evaluate the effect of four versus three loading aflibercept injections on macular fluid resolution and visual acuity (VA) in exudative neovascular AMD (nAMD). Methods: Multicentre, retrospective cohort study of treatment naïve nAMD eyes undergoing 3 versus 4 loading doses of aflibercept. Change in VA and fluid resolution on optical coherence tomography (OCT), were evaluated at 8 weeks post loading. The primary outcome was proportion of patients with no intraretinal (IRF) and/or subretinal (SRF) fluid at central 1 mm and whole macula at 8 weeks after loading. Data were summarised with mean ± SD for continuous variables, and n(%) for categorical variables. Results: Data from 995 patients was analysed (355 patients − 4 loading doses and 640–3 loading doses). At 8 weeks post 4 loading doses proportion of eyes with neither IRF nor SRF, no IRF and no SRF were 62.8%, 88.7% and 79.2% at fovea versus 56.1%, 87.9% and 69.9% in the whole macula, respectively. Fluid resolution at both fovea and macula were significantly higher in eyes with 4 loading injections versus 3 (p= 0.0001). The mean VA change was +4.0 (±11.3) and +5.4(±13.3) letters for 3 and 4 loading doses groups (p= 0.09). Conclusion: Four loading dose injections of aflibercept results in higher proportion of eyes with total fluid resolution in the central subfield and total macular scan when compared to those receiving 3 loading dose injections at 8 weeks post loading phase. However, the better drying effect of 4th loading dose does not translate into better short-term VA outcomes.

Published
2024
Full Text
View/download PDF

39. Management of Primary Hyperparathyroidism

Author

Bilezikian, John P., primary, Silverberg, Shonni J., additional, Bandeira, Francisco, additional, Cetani, Filomena, additional, Chandran, Manju, additional, Cusano, Natalie E., additional, Ebeling, Peter R., additional, Formenti, Anna Maria, additional, Frost, Morten, additional, Gosnell, Jessica, additional, Lewiecki, E. Michael, additional, Singer, Frederick R., additional, Gittoes, Neil, additional, Khan, Aliya A., additional, Marcocci, Claudio, additional, Rejnmark, Lars, additional, Ye, Zhikang, additional, Guyatt, Gordon, additional, and Potts, John T., additional

Published
2022
Full Text
View/download PDF

41. Asia‐Pacific Consensus Recommendations on X‐Linked Hypophosphatemia: Diagnosis, Multidisciplinary Management, and Transition From Pediatric to Adult Care.

Author

Munns, Craig F, Yoo, Han‐Wook, Jalaludin, Muhammad Yazid, Vasanwala, Rashida, Chandran, Manju, Rhee, Yumie, BUT, Wai Man, Kong, Alice Pik‐Shan, Su, Pen‐Hua, Numbenjapon, Nawaporn, Namba, Noriyuki, Imanishi, Yasuo, Clifton‐Bligh, Roderick J, Luo, Xiaoping, and Xia, Weibo

Subjects
TRANSITIONAL care, ADOLESCENCE, MEDICAL personnel, AGE groups, CHILD patients, HYPOPHOSPHATEMIA, MEDICAL education
Abstract

X‐linked hypophosphatemia (XLH) is a rare, inherited, multisystem disorder characterized by hypophosphatemia that occurs secondary to renal phosphate wasting. Mutations in PHEX gene (located at Xp22.1) in XLH alter bone mineral metabolism, resulting in diverse skeletal, dental, and other extraskeletal abnormalities that become evident in early childhood and persist into adolescence and adult life. XLH impacts physical function, mobility, and quality of life, and is associated with substantial socioeconomic burden and health care resource utilization. As the burden of illness varies with age, an appropriate transition of care from childhood and adolescence to adulthood is necessary to meet growth‐related changes and minimize long‐term sequelae of the condition. Previous XLH guidelines that encompassed transition of care have focused on Western experience. Regional differences in resource availability warrant tailoring of recommendations to the Asia‐Pacific (APAC) context. Hence, a core expert panel of 15 pediatric and adult endocrinologists from nine countries/regions across APAC convened to formulate evidence‐based recommendations for optimizing XLH care. A comprehensive literature search on PubMed using MeSH and free‐text terms relevant to predetermined clinical questions on diagnosis, multidisciplinary management, and transition of care of XLH revealed 2171 abstracts. The abstracts were reviewed independently by two authors to shortlist a final of 164 articles. A total of 92 full‐text articles were finally selected for data extraction and drafting the consensus statements. Sixteen guiding statements were developed based on review of evidence and real‐world clinical experience. The GRADE criteria were used to appraise the quality of evidence supporting the statements. Subsequently, a Delphi technique was utilized to rate the agreement on statements; 38 XLH experts (15 core, 20 additional, 3 international) from 15 countries/regions (12 APAC, 3 EU) participated in the Delphi voting to further refine the statements. Statements 1–3 cover the screening and diagnosis of pediatric and adult XLH; we have defined the clinical, imaging, biochemical, and genetic criteria and raised red flags for the presumptive and confirmatory diagnosis of XLH. Statements 4–12 tackle elements of multidisciplinary management in XLH such as therapeutic goals and options, composition of the multidisciplinary team, follow‐up assessments, required monitoring schedules, and the role of telemedicine. Treatment with active vitamin D, oral phosphate, and burosumab is discussed in terms of applicability to APAC settings. We also expound on multidisciplinary care for different age groups (children, adolescents, adults) and pregnant or lactating women. Statements 13–15 address facets of the transition from pediatric to adult care: targets and timelines, roles and responsibilities of stakeholders, and process flow. We explain the use of validated questionnaires, desirable characteristics of a transition care clinic, and important components of a transfer letter. Lastly, strategies to improve XLH education to the medical community are also elaborated in statement 16. Overall, optimized care for XLH patients requires prompt diagnosis, timely multidisciplinary care, and a seamless transfer of care through the coordinated effort of pediatric and adult health care providers, nurse practitioners, parents or caregivers, and patients. To achieve this end, we provide specific guidance for clinical practice in APAC settings. © 2023 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

46. Reply

Author

Lois, Noemi, primary, Saad, Ahmed, additional, Vaideanu-Collins, Daniela, additional, Azuara-Blanco, Augusto, additional, Styles, Caroline, additional, McNally, Christine, additional, Jackson, Andrew, additional, Rice, Rachael, additional, Bailey, Clare, additional, McAuley, Danny, additional, Steel, David H., additional, Barbour, Clair, additional, Bell, Leontia, additional, Ghanchi, Faruque D., additional, Madanat, Zeid, additional, Menon, Geeta, additional, Chandran, Manju, additional, Mathews, Sely, additional, Galal, Mohammed, additional, Eleftheriadis, Haralabos, additional, Efraimidis, Stefanos, additional, Cook, Jonathan, additional, Wang, Ariel, additional, Sones, William, additional, Prior, Lindsay, additional, Acharya, Nachiketa, additional, Lois, Noemi, additional, Waugh, Norman, additional, Mistry, Hema, additional, Maredza, Mandy, additional, Fatum, Samia, additional, Savage, Janette, additional, Sivaprasad, Sobha, additional, Aldington, Stephen, additional, Scanlon, Peter H., additional, Ivanova, Katerina, additional, Aslam, Tariq M., additional, Ali, Zaria, additional, and Chong, Victor, additional

Published
2021
Full Text
View/download PDF

50. Global epidemiology of hip fractures: a study protocol using a common analytical platform among multiple countries

Author

Sing, Chor-Wing, primary, Lin, Tzu-Chieh, additional, Bartholomew, Sharon, additional, Bell, J Simon, additional, Bennett, Corina, additional, Beyene, Kebede, additional, Bosco‐Lévy, Pauline, additional, Chan, Amy Hai Yan, additional, Chandran, Manju, additional, Cheung, Ching-Lung, additional, Doyon, Caroline Y, additional, Droz-Perroteau, Cécile, additional, Ganesan, Ganga, additional, Hartikainen, Sirpa, additional, Ilomaki, Jenni, additional, Jeong, Han Eol, additional, Kiel, Douglas P, additional, Kubota, Kiyoshi, additional, Lai, Edward Chia-Cheng, additional, Lange, Jeff, additional, Lewiecki, E Michael, additional, Liu, Jiannong, additional, Man, Kenneth K C, additional, Mendes de Abreu, Mirhelen, additional, Moore, Nicolas, additional, O’Kelly, James, additional, Ooba, Nobuhiro, additional, Pedersen, Alma B, additional, Prieto-Alhambra, Daniel, additional, Shin, Ju-Young, additional, Sørensen, Henrik T, additional, Tan, Kelvin Bryan, additional, Tolppanen, Anna-Maija, additional, Verhamme, Katia M C, additional, Wang, Grace Hsin-Min, additional, Watcharathanakij, Sawaeng, additional, Zhao, Hongxin, additional, and Wong, Ian C K, additional

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results