Search

Your search keyword '"Chandra Sekhar Garudadari"' showing total 3 results
Start Over Author "Chandra Sekhar Garudadari"
3 results on '"Chandra Sekhar Garudadari"'

1. Outcomes of trabeculectomy in juvenile open angle glaucoma

Author

Daizy Pathania, Sirisha Senthil, Harsha L Rao, Anil K Mandal, and Chandra Sekhar Garudadari

Subjects
Blindness, cataract, eye lens, risk factors, treatment of cataract, Low vision care, multiple disabilities and visual impairment, reading performance, Accommodation, presbyopia, supraciliary segment implants, Amblyopia, citicoline, patching, Corneal endothelium, human corneal endothelial precursor cells, in vitro expansion, sphere forming assay, thermo-reversible gelation polymer, transportation, Endophthalmitis, explantation, fungal, intraocular lens, postoperative, recurrent, Colour perception, learning disabilities, school children, stereo acuity, testability, visual acuity, Contracted socket, dermis fat graft, porous orbital implant, reconstruction, Glucose, in vitro anticataract, lens, Moringa oliefera, ′BARC I-125 Ocu-Prosta seeds′, choroidal melanoma, ciliary body melanoma, Episcleral plaque brachytherapy, retinal angioma, retinoblastoma, vasoproliferative tumor, Congenital glaucoma, gonioscopy, Retcam, Acoustic features, A-scan, B-scan, choroidal mass, ultrasound biomicroscopy, Cataract surgery, education, informed consent, multimedia, rural health, Lagophthalmos, silicone sling, temporalis muscle, Contrast sensitivity function, disability, function peak, multiple sclerosis, spatial frequency, Congenital cataract, developmental cataract, outcome, vision function, Bacterial, extracellular enzymes, keratitis, toxins, Exotropic Duane retraction syndrome, periosteal fixation, strabismus surgery, vertical rectus transposition, Descemet′s stripping endothelial keratoplasty, complications, donor dislocation, endothelial cell loss, graft failure, management, Glaucoma, glaucoma experimental, parapapillary atrophy, Juvenile open angle glaucoma, juvenile glaucoma, primary trabeculectomy, trabeculectomy in young, Ophthalmology, RE1-994
Abstract

Purpose: This study was aimed at reporting the outcomes of trabeculectomy in primary juvenile open angle glaucoma (JOAG). Design: This study was a retrospective noncomparative case series. Materials and Methods: We included 60 eyes of 41 JOAG patients who underwent primary trabeculectomy without mitomycin-C (MMC) between 1995 and 2007. The primary outcome was success, defined as complete, if intraocular pressure (IOP) was >5 and ≤21 mmHg without medications or qualified if IOP was >5 and ≤21 mmHg with or without antiglaucoma medications. Secondary outcome measures were mean and percentage IOP reduction, complications, and risk factors for the failure of trabeculectomy. Results: The mean (±standard deviation) age at presentation was 24.1 ± 6.8 years (range, 12-35). Mean follow-up was 67 ± 41 months (range, 12-156). At 1 year, the probability of complete success was 92% (n = 56, 95% CI: 81-96%), at 3 years it was 89% (n = 47, 95% CI: 78-95%), and at the end of 5 years, it was 80% (n = 34, 95% CI: 65-89%). The probability of qualified success was 100% (n = 60) at 1 year, 98% (n = 51, 95% CI: 87-100%) at 3 years, and 96% (n = 36, 95% CI: 84-99%) at the end of 5 years. The mean IOP reduced from 35 ± 10 to 13 ± 2.5 mmHg (P < 0.001) after trabeculectomy. There was no serious postoperative complication. Young age was the only significant risk factor associated with the failure (odds ratio = 0.89, P = 0.03). Conclusion: Primary trabeculectomy without MMC has good success rates in JOAG.

Published
2014
Full Text
View/download PDF

2. Outcomes of trabeculectomy in juvenile open angle glaucoma

Author

Chandra Sekhar Garudadari, Harsha L. Rao, Sirisha Senthil, Anil K Mandal, and Daizy Pathania

Subjects
Male, medicine.medical_treatment, Visual Acuity, Blindness, Low vision care, Cataract surgery, ′BARC I-125 Ocu-Prosta seeds′, lcsh:Ophthalmology, human corneal endothelial precursor cells, B-scan, Trabeculectomy, Young adult, Lagophthalmos, Child, A-scan, Endophthalmitis, multimedia, patching, school children, informed consent, Bacterial, Colour perception, retinal angioma, keratitis, silicone sling, parapapillary atrophy, dermis fat graft, explantation, glaucoma experimental, eye lens, vision function, Glaucoma, Open-Angle, medicine.medical_specialty, Accommodation, reconstruction, complications, Amblyopia, recurrent, treatment of cataract, developmental cataract, vertical rectus transposition, Humans, stereo acuity, choroidal melanoma, choroidal mass, primary trabeculectomy, trabeculectomy in young, Intraocular Pressure, Retrospective Studies, testability, Glaucoma, Odds ratio, donor dislocation, medicine.disease, Ophthalmology, Glucose, Acoustic features, disability, lcsh:RE1-994, in vitro anticataract, sphere forming assay, Juvenile open angle glaucoma, Retcam, Intraocular pressure, Visual acuity, Time Factors, Moringa oliefera, ciliary body melanoma, intraocular lens, in vitro expansion, multiple sclerosis, supraciliary segment implants, function peak, gonioscopy, risk factors, postoperative, rural health, Congenital glaucoma, periosteal fixation, education, Episcleral plaque brachytherapy, endothelial cell loss, toxins, Exotropic Duane retraction syndrome, spatial frequency, reading performance, Descemet′s stripping endothelial keratoplasty, Treatment Outcome, thermo-reversible gelation polymer, cataract, fungal, outcome, Original Article, Female, vasoproliferative tumor, medicine.symptom, management, Adult, temporalis muscle, lens, Adolescent, Corneal endothelium, graft failure, strabismus surgery, retinoblastoma, Tonometry, Ocular, Young Adult, medicine, learning disabilities, multiple disabilities and visual impairment, porous orbital implant, Congenital cataract, transportation, Contrast sensitivity function, business.industry, Postoperative complication, Retrospective cohort study, Contracted socket, extracellular enzymes, citicoline, Surgery, presbyopia, business, juvenile glaucoma, ultrasound biomicroscopy, Follow-Up Studies
Abstract

Purpose: This study was aimed at reporting the outcomes of trabeculectomy in primary juvenile open angle glaucoma (JOAG). Design: This study was a retrospective noncomparative case series. Materials and Methods: We included 60 eyes of 41 JOAG patients who underwent primary trabeculectomy without mitomycin-C (MMC) between 1995 and 2007. The primary outcome was success, defined as complete, if intraocular pressure (IOP) was >5 and ≤21 mmHg without medications or qualified if IOP was >5 and ≤21 mmHg with or without antiglaucoma medications. Secondary outcome measures were mean and percentage IOP reduction, complications, and risk factors for the failure of trabeculectomy. Results: The mean (±standard deviation) age at presentation was 24.1 ± 6.8 years (range, 12-35). Mean follow-up was 67 ± 41 months (range, 12-156). At 1 year, the probability of complete success was 92% (n = 56, 95% CI: 81-96%), at 3 years it was 89% (n = 47, 95% CI: 78-95%), and at the end of 5 years, it was 80% (n = 34, 95% CI: 65-89%). The probability of qualified success was 100% (n = 60) at 1 year, 98% (n = 51, 95% CI: 87-100%) at 3 years, and 96% (n = 36, 95% CI: 84-99%) at the end of 5 years. The mean IOP reduced from 35 ± 10 to 13 ± 2.5 mmHg (P < 0.001) after trabeculectomy. There was no serious postoperative complication. Young age was the only significant risk factor associated with the failure (odds ratio = 0.89, P = 0.03). Conclusion: Primary trabeculectomy without MMC has good success rates in JOAG.

Published
2014

3. Glaucoma in microspherophakia: presenting features and treatment outcomes

Author

Ganesh B. Jonnadula, Anil K Mandal, Uday K. Addepalli, Chandra Sekhar Garudadari, Nguyen T.Q. Hoang, Harsha L. Rao, and Sirisha Senthil

Subjects
Adult, Male, Intraocular pressure, medicine.medical_specialty, genetic structures, Open angle glaucoma, Adolescent, medicine.medical_treatment, Gonioscopy, Visual Acuity, Glaucoma, Iris, Ectopia Lentis, Corneal Diseases, Tonometry, Ocular, Young Adult, Ophthalmology, Vitrectomy, Lens, Crystalline, medicine, Glaucoma surgery, Trabeculectomy, Humans, Child, Antihypertensive Agents, Intraocular Pressure, Retrospective Studies, Laser Coagulation, medicine.diagnostic_test, business.industry, Infant, Newborn, Infant, Middle Aged, medicine.disease, eye diseases, Microspherophakia, Treatment Outcome, Child, Preschool, Female, sense organs, business, Glaucoma, Angle-Closure, Laser coagulation, Glaucoma, Open-Angle
Abstract

Purpose To report the clinical features, management, and treatment outcomes of glaucoma in microspherophakia. Methods Medical records of 159 eyes of 80 subjects with microspherophakia were reviewed. The clinical features at presentation, presence of glaucoma, methods of treatment, and their outcomes were noted. Glaucoma was diagnosed based on intraocular pressure (IOP)≥22 mm Hg on 2 different occasions and/or glaucomatous optic disc damage. Angle closure was defined as occludable angles >270 degrees with or without presence of peripheral anterior synechiae. Results Glaucoma was diagnosed in 81 eyes (51%). The mean age of subjects was 20±13 years, mean refractive error was -13.5±5.5, the mean IOP was 27.7±11.1 mm Hg. IOP≥22 mm Hg was present in 84% of eyes, disc damage in 59% of the eyes, 75% eyes had angle closure, and 25% had open angle on gonioscopy. Subluxation of crystalline lens was seen in 53 eyes and 14 eyes had dislocation of the lens; systemic associations were present in 21 subjects (3 Marfan syndrome, 18 Weill-Marchesani syndrome). Nine eyes out of 51 and 2 out of 16 eyes responded to medical treatment and laser iridotomy, respectively. Of the 48 eyes that required surgical intervention, 24 eyes underwent trabeculectomy. Complete success probability of trabeculectomy was 86% [95% confidence interval (CI), 63%-95%] at 6 months, 77% (95% CI, 53%-90%) at 1 year, which was maintained till 7 years, and reduced to 61% (95% CI, 26%-84%) at 8 years. Nearly 20% of eyes at presentation and 30% of the eyes at last follow-up were blind due to glaucoma. Conclusions More than half of the eyes with microspherophakia in this series presented with glaucoma; angle closure was the predominant form of glaucoma. Blindness due to glaucoma in microspherophakia was 20% to 30%.

Published
2012

Catalog

Books, media, physical & digital resources
See catalog results