Search

Your search keyword '"Chan, Hoi-Hung"' showing total 233 results
Start Over Author "Chan, Hoi-Hung"
233 results on '"Chan, Hoi-Hung"'

5. Leukocyte cell-derived chemotaxin 2 regulates epithelial-mesenchymal transition and cancer stemness in hepatocellular carcinoma

Author

Chu, Tian-Huei, primary, Ko, Chou-Yuan, additional, Tai, Po-Han, additional, Chang, Yi-Chen, additional, Huang, Chao-Cheng, additional, Wu, Tung-Yang, additional, Chan, Hoi-Hung, additional, Wu, Ping-Hsuan, additional, Weng, Chien-Hui, additional, Lin, Yu-Wei, additional, Kung, Mei-Lang, additional, Fang, Cheng-Chieh, additional, Wu, Jian-Ching, additional, Wen, Zhi-Hong, additional, Lee, Yung-Kuo, additional, Hu, Tsung-Hui, additional, and Tai, Ming-Hong, additional

Published
2022
Full Text
View/download PDF

14. Hepatoma‐derived growth factor participates in concanavalin A‐induced hepatitis

Author

Wang, E‐Ming, primary, Hu, Tsung‐Hui, additional, Huang, Chao‐Cheng, additional, Chang, Yi‐Chen, additional, Yang, Shih‐Ming, additional, Huang, Shih‐Tsung, additional, Wu, Jian‐Ching, additional, Ma, Yi‐Ling, additional, Chan, Hoi‐Hung, additional, Liu, Li‐Feng, additional, Lu, Wen‐Bin, additional, Kung, Mei‐Lang, additional, Wen, Zhi‐Hong, additional, Wang, Jui‐Chu, additional, Ko, Chou‐Yuan, additional, Tsai, Wei‐Lun, additional, Chu, Tian‐Huei, additional, and Tai, Ming‐Hong, additional

Published
2020
Full Text
View/download PDF

27. Factors linked to severe thrombocytopenia during antiviral therapy in patients with chronic hepatitis c and pretreatment low platelet counts

Author

Lin Kung-Hung, Hsu Ping-I, Yu Hsien-Chung, Lin Chun-Ku, Tsai Wei-Lun, Chen Wen-Chi, Chan Hoi-Hung, and Lai Kwok-Hung

Subjects
HCV, peg-IFN-α, ribavirin, thrombocytopenia, Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

Abstract Background Baseline low platelet count (< 150,000/μL) increases the risk of on-treatment severe thrombocytopenia (platelet count < 50,000/μL) in patients with chronic hepatitis C (CHC) undergoing antiviral therapy, which may interrupt treatment. The purpose of this study was to identify risk factors for severe thrombocytopenia during treatment for CHC in patients with baseline thrombocytopenia. Methods Medical records were reviewed for 125 patients with CHC treated with antiviral therapy according to the standard of care, with regular follow-up examinations. Early platelet decline was defined as platelet decrease during the first 2 weeks of therapy. Results Severe thrombocytopenia developed in 12.8% of patients with baseline thrombocytopenia, and predicted a higher therapeutic dropout rate. Multivariate analysis revealed baseline platelet count < 100,000/μL and rapid early platelet decline (> 30% decline in the first 2 weeks) were significantly associated with severe thrombocytopenia (P < 0.001 and 0.003, odds ratios, 179.22 and 45.74, respectively). In these patients, baseline PLT ≥ 100,000/μL and lack of rapid early platelet decline predicted absence of severe thrombocytopenia (negative predictive values were 95.1% and 96.6%, respectively). In contrast, baseline platelet count < 100,000/μL combined with rapid early platelet decline predicted severe thrombocytopenia (positive predictive value was 100%). Conclusions For patients with CHC on antiviral therapy, baseline platelet counts < 100,000/μL and rapid early platelet decline can identify patients at high risk of developing on-treatment severe thrombocytopenia.

Published
2012
Full Text
View/download PDF

29. Endoscopic papillary large balloon dilation alone without sphincterotomy for the treatment of large common bile duct stones

Author

Chen Wen-Chi, Hsu Ping-I, Wang E-Ming, Tsai Wei-Lun, Lin Chiun-Ku, Lai Kwok-Hung, Chan Hoi-Hung, Yu Hsien-Chung, Wang Huay-Min, Tsay Feng-Woei, Tsai Cheng-chung, Chen I-Shu, Chen Yu-chia, Liang Huei-Lung, and Pan Huay-Ben

Subjects
Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

Abstract Background Lethal pancreatitis has been reported after treatment for common bile duct stones using small endoscopic papillary balloon dilation. Methods We retrospectively evaluated the safety and efficacy of using large balloon dilation alone without the use of sphincterotomy for the treatment of large common bile duct stones in Kaohsiung Veterans General Hospital. Success rate of stone clearance, procedure-related adverse events and incidents, frequency of mechanical lithotripsy use, and recurrent stones were recorded. Results A total of 247 patients were reviewed in the current study. The mean age of the patients was 71.2 years. Most of them had comorbidities. Mean stone size was 16.4 mm. Among the patients, 132 (53.4%) had an intact gallbladder and 121 (49%) had a juxtapapillary diverticulum. The mean size of dilating balloon used was 13.2 mm. The mean duration of the dilating procedure was 4.7 min. There were 39 (15.8%) patients required the help of mechanical lithotripsy while retrieving the stones. The final success rate of complete retrieval of stones was 92.7%. The rate of pancreatic duct enhancement was 26.7% (66/247). There were 3 (1.2%) adverse events and 6 (2.4%) intra-procedure bleeding incidents. All patients recovered completely after conservative and endoscopic treatment respectively, and no procedure-related mortality was noted. 172 patients had a follow-up duration of more than 6 months and among these, 25 patients had recurrent common bile duct stones. It was significantly correlated to the common bile duct size (p = 0.036) Conclusions Endoscopic papillary large balloon dilation alone is simple, safe, and effective in dealing with large common bile duct stones in relatively aged and debilitated patients.

Published
2011
Full Text
View/download PDF

31. Rapid induction of orthotopic hepatocellular carcinoma in immune-competent rats by non-invasive ultrasound-guided cells implantation

Author

Pan Huay-Ben, Wang E-Ming, Sun Cheuk-Kwan, Chien Hsin-Fan, Chu Tian-Huei, Chan Hoi-Hung, Kuo Hsiao-Mei, Hu Tsung-Hui, Lai Kwok-Hung, Cheng Jiin-Tsuey, and Tai Ming-Hong

Subjects
Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

Abstract Background The fact that prognoses remain poor in patients with advanced hepatocellular carcinoma highlights the demand for suitable animal models to facilitate the development of anti-cancer medications. This study employed a relatively non-invasive approach to establish an orthotopic hepatocellular carcinoma model in immune-competent rats. This was done by ultrasound-guided implantation of cancer cells and the model was used to evaluate the therapeutic efficacy of short-term and low-dose epirubicin chemotherapy. Methods Rat Novikoff hepatoma cells were injected percutaneously into the liver lobes of Sprague-Dawley rats under the guidance of high resolution ultrasound. The implantation rate and the correlation between dissected and ultrasound-measured tumor sizes were evaluated. A similar induction procedure was performed by means of laparotomy in a different group of rats. Pairs of tumor measurement were compared by ultrasound and computerized tomography scan. Rats with a successful establishment of the tumor were divided into the treatment (7-day low-dose epirubicin) group and the control group. The tumor sizes were non-invasively monitored by the same ultrasound machine. Blood and tumor tissues from tumor-bearing rats were examined by biochemical and histological analysis respectively. Results Ultrasound-guided implantation of Novikoff hepatoma cells led to the formation of orthotopic hepatocellular carcinoma in 60.4% (55/91) of the Sprague-Dawley rats. Moreover, tumor sizes measured by ultrasound significantly correlated with those measured by calipers after sacrificing the animals (P < 0.00001). The rate of tumor induction by ultrasound-guided implantation was comparable to that of laparotomy (55/91, 60.4% vs. 39/52, 75%) and no significant difference in sizes of tumor was noted between the two groups. There was a significant correlation in tumor size measurement by ultrasound and computerized tomography scan. In tumor-bearing rats, short-term and low-dose epirubicin chemotherapy caused a significant reduction in tumor growth, and was found to be associated with enhanced apoptosis and attenuated proliferation as well as a decrease in the microvessel density in tumors. Conclusions Ultrasound-guided implantation of Novikoff hepatoma cells is an effective means of establishing orthotopic hepatocellular carcinoma in Sprague-Dawley rats. Short-term and low-dose epirubicin chemotherapy had perturbed tumor progression by inducing apoptosis and neovascularization blockade.

Published
2010
Full Text
View/download PDF

35. Celecoxib enhances the therapeutic efficacy of epirubicin for Novikoff hepatoma in rats

Author

Chu, Tian-Huei, primary, Chan, Hoi-Hung, additional, Hu, Tsung-Hui, additional, Wang, E-Ming, additional, Ma, Yi-Ling, additional, Huang, Shih-Chung, additional, Wu, Jian-Ching, additional, Chang, Yi-Chen, additional, Weng, Wen-Tsan, additional, Wen, Zhi-Hong, additional, Wu, Deng-Chyang, additional, Chen, Yi-Ming Arthur, additional, and Tai, Ming-Hong, additional

Published
2018
Full Text
View/download PDF

36. Comparison of repeated surgical resection and radiofrequency ablation for small recurrent hepatocellular carcinoma after primary resection

Author

Sun, Wei-Chi, primary, Chen, I-Shu, additional, Liang, Huei-Lung, additional, Tsai, Cheng-Chung, additional, Chen, Yu-Chia, additional, Wang, Being-Whey, additional, Lin, Huey-Shyan, additional, Chan, Hoi-Hung, additional, Hsu, Ping-I, additional, Tsai, Wei-Lun, additional, and Cheng, Jin-Shiung, additional

Published
2017
Full Text
View/download PDF

40. Improvement of Short-Term Outcomes for High-Risk Bleeding Peptic Ulcers With Addition of Argon Plasma Coagulation Following Endoscopic Injection Therapy

Author

Wang, Huay-Min, Tsai, Wei-Lun, Yu, Hsien-Chung, Chan, Hoi-Hung, Chen, Wen-Chi, Lin, Kung-Hung, Tsai, Tzung-Jiun, Kao, Sung-Shuo, Sun, Wei-Chih, and Hsu, Ping-I.

Subjects
Male, Peptic Ulcer, Argon Plasma Coagulation, Water, Hemorrhage, Clinical Trial/Experimental Study, Middle Aged, Gastroscopy, Humans, Female, Prospective Studies, Research Article, Aged
Abstract

A second endoscopic method together with injection therapy is recommended to treat high-risk bleeding peptic ulcers. This study investigated whether additional argon plasma coagulation (APC) treatment could influence hemostatic efficacy following endoscopic injection therapy to treat high-risk bleeding ulcers. From October 2010 to January 2012, eligible patients with high-risk bleeding ulcers were admitted to our hospital. They prospectively randomly underwent either APC therapy along with distilled water injection or distilled water injection alone. Episodes of rebleeding were retreated with endoscopic combination therapy. Patients in whom retreatment was ineffective underwent emergency surgery or transarterial embolization (TAE). A total of 116 enrolled patients were analyzed. The hemostatic efficacy in 58 patients treated with APC along with distilled water injection was compared with that in 58 patients treated with distilled water injection alone. The 2 treatment groups were similar with respect to all baseline characteristics. Initial hemostasis was accomplished in 56 patients treated with combined therapy, and 55 patients treated with distilled water injection therapy (97% vs 95%, P = 0.648). Bleeding recurred in 2 patients treated with combined therapy, and 9 patients treated with distilled water injection (3.6% vs 16%, P = 0.029). Treatment method was the only independent prognostic factor for recurrent bleeding (odds ratio 0.17; 95% confidence interval 0.03–0.84; P = 0.029). The 2 groups did not differ significantly in hospital stay, TAE, surgery, and mortality. Endoscopic therapy with APC following distilled water injection is more effective than distilled water injection alone for preventing rebleeding of peptic ulcer.

Published
2015

41. Is endoscopic treatment beneficial in patients with clinically suspicious of common bile duct stones but no obvious filling defects during the ERCP examination?

Author

Chiang, Po-Hung, primary, Lai, Kwok-Hung, additional, Tsai, Tzung-Jiun, additional, Lin, Kung-Hung, additional, Wang, Kai-Ming, additional, Kao, Sung-Shuo, additional, Sun, Wei-Chih, additional, Cheng, Jin-Shiung, additional, Hsu, Ping-I, additional, Tsai, Wei-Lun, additional, Chen, Wen-Chi, additional, Li, Yun-Da, additional, Wang, E-Ming, additional, Lin, Huey-Shyan, additional, and Chan, Hoi-Hung, additional

Published
2016
Full Text
View/download PDF

43. International consensus guidelines for endoscopic papillary large-balloon dilation

Author

Kim, Tae Hyeon, primary, Kim, Jin Hong, additional, Seo, Dong Wan, additional, Lee, Dong Ki, additional, Reddy, Nageshwar D., additional, Rerknimitr, Rungsun, additional, Ratanachu-Ek, Thawee, additional, Khor, Christopher J.L., additional, Itoi, Takao, additional, Yasuda, Ichiro, additional, Isayama, Hiroyuki, additional, Lau, James Y.W., additional, Wang, Hsiu-Po, additional, Chan, Hoi-Hung, additional, Hu, Bing, additional, Kozarek, Richard A., additional, and Baron, Todd H., additional

Published
2016
Full Text
View/download PDF

45. Hepatoma-derived growth factor/nucleolin axis as a novel oncogenic pathway in liver carcinogenesis

Author

Chen, San-Cher, primary, Hu, Tsung-Hui, additional, Huang, Chao-Cheng, additional, Kung, Mei-Lang, additional, Chu, Tian-Huei, additional, Yi, Li-Na, additional, Huang, Shih-Tsung, additional, Chan, Hoi-Hung, additional, Chuang, Jiin-Haur, additional, Liu, Li-Feng, additional, Wu, Han-Chung, additional, Wu, Deng-Chyang, additional, Chang, Min-Chi, additional, and Tai, Ming-Hong, additional

Published
2015
Full Text
View/download PDF

46. The Efficacy of Endoscopic Papillary Balloon Dilation for Patients with Acute Biliary Pancreatitis

Author

Sun, Wei-Chih, primary, Chan, Hoi-Hung, additional, Lai, Kwok-Hung, additional, Tsai, Tzung-Jiun, additional, Lin, Huey-Shyan, additional, Lin, Kung-Hung, additional, Wang, Kai-Ming, additional, Kao, Sung-Shuo, additional, Chiang, Po-Hung, additional, Cheng, Jin-Shiung, additional, Hsu, Ping-I, additional, Tsai, Wei-Lun, additional, Chen, Wen-Chi, additional, Li, Yun-Da, additional, and Wang, E-Ming, additional

Published
2015
Full Text
View/download PDF

47. Reverse Sequential Therapy Achieves a Similar Eradication Rate as Standard Sequential Therapy forHelicobacter pyloriEradication: A Randomized Controlled Trial

Author

Tsay, Feng-Woei, primary, Wu, Deng-Chyang, additional, Kao, Sung-Shuo, additional, Tsai, Tzung-Jium, additional, Lai, Kwok-Hung, additional, Cheng, Jin-Shiung, additional, Chan, Hoi-Hung, additional, Wang, Huay-Min, additional, Tsai, Wei-Lun, additional, Tseng, Hui-Hwa, additional, Peng, Nan-Jin, additional, and Hsu, Ping-I, additional

Published
2014
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results