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1. 18 Haemoglobin a1c predicts average glucose by continuous glucose monitoring in youth with cystic fibrosis

Author: Hope, E, Thurston, J, Vigers, T, Pyle, L, Zeitler, P, Nadeau, KJ, and Chan, CL
Published: 2018
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2. Epidemiological study of orthopedic injuries in hemodialysis patients in Taiwan: a fixed cohort survey, 2004–2008

Author: Chang NT, Lee YH, Hsu JC, Chan CL, Huang GS, Renn JH, and Yang NP
Subjects: Chronic Kidney Disease, Renal Osteodystrophy, Hemodialysis, Orthopedic Injuries, Geriatrics, RC952-954.6
Abstract: Nien-Tzu Chang,1,2,* Yi-Hui Lee,2,3 Jiin-Chyr Hsu,4 Chien-Lung Chan,5 Guey-Shiun Huang,2 Jenn-Huei Renn,1,6,* Nan-Ping Yang1,4,* 1Community Health Research Center and Institute of Public Health, National Yang-Ming University, Taipei, Taiwan; 2Department of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan; 3Department of Nursing, School of Nursing, Chang-Gang University, Taoyuan, Taiwan; 4Department of Medical Research and Biostatistics Office, Tao-Yuan General Hospital, Department of Health, Taoyuan, Taiwan; 5Department of Information Management, Yuan-Ze University, Taoyuan, Taiwan; 6Department of Orthopedics, Kaohsiung Veterans General Hospital, Executive Yuan, Kaohsiung, Taiwan*These authors contributed equally to this workBackground: The burden of chronic kidney disease (CKD) is a growing concern worldwide. The prevalence of hemodialysis in Taiwan is the highest in the world, and this may increase the prevalence of orthopedic fractures. The aim of this study was to explore the incidences of various orthopedic injuries and the related risk factors.Methods: A nationwide prospective study based on the Taiwan National Health Insurance dataset was conducted during 2004–2008. A total of 82,491 CKD patients were selected as the fixed cohort population. The International Classification of Diseases 9-CM diagnosis codes and treatment codes were identified as the inclusion criteria for orthopedic injury.Results: A total of 82,491 Taiwanese people with CKD were identified in 2004, and 4915 orthopedic injuries occurred during the 5-year follow-up period. The cumulative incidences of orthopedic injuries were 42.56‰ for lower limb fractures, and 12.93‰, 3.27‰, and 1.64‰ for upper limb fractures, vertebrae fractures, and joint dislocations, respectively. All three types of orthopedic fractures were more common in the oldest age stratum (≥65 years old). In the CKD patients, the risk ratio of osteoporosis was 3.47 (95% confidence interval, 3.10–3.89) for all orthopedic injuries. Patients of advanced age, the female gender, and those with high comorbidity were also at significant risk of sustaining orthopedic fractures.Conclusion: The results from this Taiwanese CKD cohort support the strong influence of aging and osteoporosis on all kinds of orthopedic injuries. The postponing of osteoporosis may need to be taken into consideration for the prevention of orthopedic injury among CKD patients undergoing hemodialysis.Keywords: chronic kidney disease, renal osteodystrophy, hemodialysis, orthopedic injuries
Published: 2013

3. Stromal cell diversity associated with immune evasion in human triple-negative breast cancer

Author: Wu, SZ, Roden, DL, Wang, C, Holliday, H, Harvey, K, Cazet, AS, Murphy, KJ, Pereira, B, Al-Eryani, G, Bartonicek, N, Hou, R, Torpy, JR, Junankar, S, Chan, CL, Lam, CE, Hui, MN, Gluch, L, Beith, J, Parker, A, Robbins, E, Segara, D, Mak, C, Cooper, C, Warrier, S, Forrest, A, Powell, J, O'Toole, S, Cox, TR, Timpson, P, Lim, E, Liu, XS, Swarbrick, A, Wu, SZ, Roden, DL, Wang, C, Holliday, H, Harvey, K, Cazet, AS, Murphy, KJ, Pereira, B, Al-Eryani, G, Bartonicek, N, Hou, R, Torpy, JR, Junankar, S, Chan, CL, Lam, CE, Hui, MN, Gluch, L, Beith, J, Parker, A, Robbins, E, Segara, D, Mak, C, Cooper, C, Warrier, S, Forrest, A, Powell, J, O'Toole, S, Cox, TR, Timpson, P, Lim, E, Liu, XS, and Swarbrick, A
Abstract: The tumour stroma regulates nearly all stages of carcinogenesis. Stromal heterogeneity in human triple-negative breast cancers (TNBCs) remains poorly understood, limiting the development of stromal-targeted therapies. Single-cell RNA sequencing of five TNBCs revealed two cancer-associated fibroblast (CAF) and two perivascular-like (PVL) subpopulations. CAFs clustered into two states: the first with features of myofibroblasts and the second characterised by high expression of growth factors and immunomodulatory molecules. PVL cells clustered into two states consistent with a differentiated and immature phenotype. We showed that these stromal states have distinct morphologies, spatial relationships and functional properties in regulating the extracellular matrix. Using cell signalling predictions, we provide evidence that stromal-immune crosstalk acts via a diverse array of immunoregulatory molecules. Importantly, the investigation of gene signatures from inflammatory-CAFs and differentiated-PVL cells in independent TNBC patient cohorts revealed strong associations with cytotoxic T-cell dysfunction and exclusion, respectively. Such insights present promising candidates to further investigate for new therapeutic strategies in the treatment of TNBCs.
Published: 2020

4. Development and validation of a targeted gene sequencing panel for application to disparate cancers

Author: McCabe, MJ, Gauthier, MEA, Chan, CL, Thompson, TJ, De Sousa, SMC, Puttick, C, Grady, JP, Gayevskiy, V, Tao, J, Ying, K, Cipponi, A, Deng, N, Swarbrick, A, Thomas, ML, Lord, RV, Johns, AL, Kohonen-Corish, M, O’Toole, SA, Clark, J, Mueller, SA, Gupta, R, McCormack, AI, Dinger, ME, Cowley, MJ, Aghmesheh, M, Amor, D, Andrews, L, Antill, Y, Armitage, S, Arnold, L, Balleine, R, Bastick, P, Beesley, J, Beilby, J, Bennett, I, Blackburn, A, Bogwitz, M, Botes, L, Brennan, M, Brown, M, Buckley, M, Burgess, M, Burke, J, Butow, P, Caldon, L, Callen, D, Campbell, I, Chauhan, D, Chauhan, M, Chenevix-Trench, G, Christian, A, Clarke, C, Cohen, P, Colley, A, Crook, A, Cui, J, Culling, B, Cummings, M, Dawson, SJ, deFazio, A, Delatycki, M, Dickson, R, Dixon, J, Dobrovic, A, Dudding, T, Edkins, T, Edwards, S, Eisenbruch, M, Farshid, G, Fellows, A, Fenton, G, Field, M, Flanagan, J, Fong, P, Forrest, L, Fox, S, French, J, Friedlander, M, Gaff, C, Ortega, DG, Gattas, M, George, P, Giles, G, Gill, G, Greening, S, Haan, E, Harris, M, Hart, S, Hayward, N, Heiniger, L, Hopper, J, Hunt, C, James, P, Jenkins, M, Kefford, R, Kidd, A, Kirk, J, Koehler, J, Kollias, J, and Lakhani, S
Abstract: © 2019, The Author(s). Next generation sequencing has revolutionised genomic studies of cancer, having facilitated the development of precision oncology treatments based on a tumour’s molecular profile. We aimed to develop a targeted gene sequencing panel for application to disparate cancer types with particular focus on tumours of the head and neck, plus test for utility in liquid biopsy. The final panel designed through Roche/Nimblegen combined 451 cancer-associated genes (2.01 Mb target region). 136 patient DNA samples were collected for performance and application testing. Panel sensitivity and precision were measured using well-characterised DNA controls (n = 47), and specificity by Sanger sequencing of the Aryl Hydrocarbon Receptor Interacting Protein (AIP) gene in 89 patients. Assessment of liquid biopsy application employed a pool of synthetic circulating tumour DNA (ctDNA). Library preparation and sequencing were conducted on Illumina-based platforms prior to analysis with our accredited (ISO15189) bioinformatics pipeline. We achieved a mean coverage of 395x, with sensitivity and specificity of >99% and precision of >97%. Liquid biopsy revealed detection to 1.25% variant allele frequency. Application to head and neck tumours/cancers resulted in detection of mutations aligned to published databases. In conclusion, we have developed an analytically-validated panel for application to cancers of disparate types with utility in liquid biopsy.
Published: 2019

5. Introduction to risk management plans in the Singapore context

Author: Ho, CSC, primary, Tan, LLB, additional, and Chan, CL, additional
Published: 2019
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6. Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer

Author: Cazet, AS, Hui, MN, Elsworth, BL, Wu, SZ, Roden, D, Chan, CL, Skhinas, JN, Collot, R, Yang, J, Harvey, K, Johan, MZ, Cooper, C, Nair, R, Herrmann, D, McFarland, A, Deng, N, Ruiz-Borrego, M, Rojo, F, Trigo, JM, Bezares, S, Caballero, R, Lim, E, Timpson, P, O’Toole, S, Watkins, DN, Cox, TR, Samuel, MS, Martín, M, Swarbrick, A, Cazet, AS, Hui, MN, Elsworth, BL, Wu, SZ, Roden, D, Chan, CL, Skhinas, JN, Collot, R, Yang, J, Harvey, K, Johan, MZ, Cooper, C, Nair, R, Herrmann, D, McFarland, A, Deng, N, Ruiz-Borrego, M, Rojo, F, Trigo, JM, Bezares, S, Caballero, R, Lim, E, Timpson, P, O’Toole, S, Watkins, DN, Cox, TR, Samuel, MS, Martín, M, and Swarbrick, A
Abstract: The cellular and molecular basis of stromal cell recruitment, activation and crosstalk in carcinomas is poorly understood, limiting the development of targeted anti-stromal therapies. In mouse models of triple negative breast cancer (TNBC), Hedgehog ligand produced by neoplastic cells reprograms cancer-associated fibroblasts (CAFs) to provide a supportive niche for the acquisition of a chemo-resistant, cancer stem cell (CSC) phenotype via FGF5 expression and production of fibrillar collagen. Stromal treatment of patient-derived xenografts with smoothened inhibitors (SMOi) downregulates CSC markers expression and sensitizes tumors to docetaxel, leading to markedly improved survival and reduced metastatic burden. In the phase I clinical trial EDALINE, 3 of 12 patients with metastatic TNBC derived clinical benefit from combination therapy with the SMOi Sonidegib and docetaxel chemotherapy, with one patient experiencing a complete response. These studies identify Hedgehog signaling to CAFs as a novel mediator of CSC plasticity and an exciting new therapeutic target in TNBC.
Published: 2018

7. Pacing across the membrane: the novel PACE family of efflux pumps is widespread in Gram-negative pathogens.

Author: Hassan, KA, Liu, Q, Elbourne, LDH, Ahmad, I, Sharples, D, Naidu, V, Chan, CL, Li, L, Harborne, SPD, Pokhrel, A, Postis, VLG, Goldman, A, Henderson, PJF, Paulsen, IT, Hassan, KA, Liu, Q, Elbourne, LDH, Ahmad, I, Sharples, D, Naidu, V, Chan, CL, Li, L, Harborne, SPD, Pokhrel, A, Postis, VLG, Goldman, A, Henderson, PJF, and Paulsen, IT
Abstract: The proteobacterial antimicrobial compound efflux (PACE) family of transport proteins was only recently described. PACE family transport proteins can confer resistance to a range of biocides used as disinfectants and antiseptics, and are encoded by many important Gram-negative human pathogens. However, we are only just beginning to appreciate the range of functions and the mechanism(s) of transport operating in these proteins. Genes encoding PACE family proteins are typically conserved in the core genomes of bacterial species rather than on recently acquired mobile genetic elements, suggesting that they confer important core functions in addition to biocide resistance. Three-dimensional structural information is not yet available for PACE family proteins. However, PACE proteins have several very highly conserved amino acid sequence motifs that are likely to be important for substrate transport. PACE proteins also display strong amino acid sequence conservation between their N and C-terminal halves, suggesting that they evolved by duplication of an ancestral protein comprised of two transmembrane helices. In light of their drug resistance functions in Gram-negative pathogens, PACE proteins should be the subject of detailed future investigation.
Published: 2018

8. CONSORT 2010 statement: extension to randomised pilot and feasibility trials [on behalf of the PAFS consensus group*]

Author: Eldridge, SM, Chan, CL, Campbell, MJ, Bond, CM, Hopewell, S, Thabane, L, Lancaster, GA, Altman, Doug, Bretz, Frank, Campbell, Marion, Cobo, Erik, Craig, Peter, Davidson, Peter, Groves, Trish, Gumedze, Freedom, Hewison, Jenny, Hirst, Allison, Hoddinott, Pat, Lamb, Sarah E., Lang, Tom, McColl, Elaine, O'Cathain, Alicia, Shanahan, Daniel R., Sutton, Chris J, Tugwell, Peter, Lamb, Sarah E, and Shanahan, Daniel R
Subjects: G350, G300, G200, G290, G190, G390
Abstract: The Consolidated Standards of Reporting Trials (CONSORT) statement is a guideline designed to improve the transparency and quality of the reporting of randomised controlled trials (RCTs). In this article we present an extension to that statement for randomised pilot and feasibility trials conducted in advance of a future definitive RCT. The checklist applies to any randomised study in which a future definitive RCT, or part of it, is conducted on a smaller scale, regardless of its design (eg, cluster, factorial, crossover) or the terms used by authors to describe the study (eg, pilot, feasibility, trial, study). The extension does not directly apply to internal pilot studies built into the design of a main trial, non-randomised pilot and feasibility studies, or phase II studies, but these studies all have some similarities to randomised pilot and feasibility studies and so many of the principles might also apply.\ud \ud The development of the extension was motivated by the growing number of studies described as feasibility or pilot studies and by research that has identified weaknesses in their reporting and conduct. We followed recommended good practice to develop the extension, including carrying out a Delphi survey, holding a consensus meeting and research team meetings, and piloting the checklist.\ud \ud The aims and objectives of pilot and feasibility randomised studies differ from those of other randomised trials. Consequently, although much of the information to be reported in these trials is similar to those in randomised controlled trials (RCTs) assessing effectiveness and efficacy, there are some key differences in the type of information and in the appropriate interpretation of standard CONSORT reporting items. We have retained some of the original CONSORT statement items, but most have been adapted, some removed, and new items added. The new items cover how participants were identified and consent obtained; if applicable, the prespecified criteria used to judge whether or how to proceed with a future definitive RCT; if relevant, other important unintended consequences; implications for progression from pilot to future definitive RCT, including any proposed amendments; and ethical approval or approval by a research review committee confirmed with a reference number.\ud \ud This article includes the 26 item checklist, a separate checklist for the abstract, a template for a CONSORT flowchart for these studies, and an explanation of the changes made and supporting examples. We believe that routine use of this proposed extension to the CONSORT statement will result in improvements in the reporting of pilot trials.\ud \ud Editor’s note: In order to encourage its wide dissemination this article is freely accessible on the BMJ and Pilot and Feasibility Studies journal websites.
Published: 2016

9. 0926 CONTINUOUS GLUCOSE MONITORING, INSULIN RESISTANCE, AND SLEEP IN ADOLESCENTS WITH CYSTIC FIBROSIS

Author: Simon, SL, primary, Vigers, T, additional, Campbell, K, additional, Pyle, L, additional, Branscomb, R, additional, Nadeau, K, additional, and Chan, CL, additional
Published: 2017
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10. Ultrasound Directed Oocyte Recovery in an IVF Program

Author: M.P.R. Hamilton, S. C. Ng, T. A. Bongso, C. Anandakumar, P.C. Wong, S. S. Ratnam, Chan Cl, and Y. C. Wong
Subjects: medicine.medical_specialty, medicine.diagnostic_test, business.industry, Ultrasound, Obstetrics and Gynecology, Fertilization in Vitro, Anatomy, Transvaginal oocyte recovery, Transvaginal approach, Transurethral route, Surgery, Ultrasound guidance, Oocytes, medicine, Humans, Female, Laparoscopy, In patient, Oocyte recovery, business, Ultrasonography
Abstract: Sixty-three patients who underwent the IVF program had oocyte recovery done under ultrasound guidance. These patients were previously found to have inaccessible or partially inaccessible ovaries at laparoscopy. Twenty patients had oocyte recovery by the transurethral route while 43 were carried out by the transvaginal approach. In the transurethral group, 96 follicles (4.8 follicles per patient) were aspirated and 55 oocytes were recovered (57.3%) or 2.75 oocytes per patient. In the transvaginal group, 216 follicles (5.0 follicles per patient) were aspirated and 104 oocytes were recovered (48.1%) or 2.41 oocytes per patient. Ultrasound-guided oocyte recovery is a satisfactory method of oocyte recovery in patients with inaccessible or partially inaccessible ovaries.
Published: 2010
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11. The First 2 Case Reports of Frozen Embryo Donation Twin Pregnancies in Singapore: Hormonal Profiles and Obstetrical Outcome

Author: Chui Y. Fong, J. Kumar, Chan Cl, Eu Leong Yong, Soon Chye Ng, and Ariff Bongso
Subjects: Adult, medicine.medical_specialty, Gonadal dysgenesis, Embryo cryopreservation, Pregnancy, medicine, Humans, Chorionic Gonadotropin, beta Subunit, Human, Progesterone, Gynecology, Singapore, Estradiol, Obstetrics, business.industry, Antepartum haemorrhage, Obstetrics and Gynecology, Embryo Transfer, medicine.disease, Embryo transfer, Premature ovarian failure, Gestation, Female, Pregnancy, Multiple, business, Infertility, Female, Premature rupture of membranes, Hormone
Abstract: A 35-year-old woman with premature ovarian failure and another 30-year-old woman with gonadal dysgenesis were the recepients of donated supernumerous frozen embryos after successfully prepared with cyclic steroid replacement therapy as described previously.1,2) One patient received 4 and the second 2 frozen embryos, transferred transcer-vically on the 3rd day of progesterone administration. Both patients had viable twin pregnancies. The plasma βhCG levels for both patients at 2 weeks post replacement (4 weeks gestation) were lower than the median values in our normal, uncomplicated singleton pregnancy for the same gestation. The levels after 4 weeks post-replacement (6 weeks gestation) became comparable. Plasma progesterone profiles suggested a level of above 70 ng/ml would be enough to support the twin pregnancies. The first patient developed antepartum haemorrhage of unknown origin at 34 weeks of gestation preceding preterm premature rupture of membranes and subsequently had preterm labour. The second patient developed proteinuric hypertension at 33 weeks of gestation. Both ended in a lower segment cesarean section. Both sets of twins and their mothers were discharged well.
Published: 1998
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12. A new molecular variant of luteinizing hormone associated with female infertility

Author: Ashim C. Roy, Shan S. Ratnam, Sabaratnam Arulkumaran, W.-X. Liao, and Chan Cl
Subjects: Adult, Infertility, Heterozygote, medicine.medical_specialty, Molecular Sequence Data, Endometriosis, Primary Ovarian Insufficiency, Biology, Polymerase Chain Reaction, Exon, Obstetrics and gynaecology, medicine, Humans, Missense mutation, Amino Acid Sequence, Genetic Testing, Menstruation Disturbances, Gynecology, Base Sequence, Sequence Homology, Amino Acid, business.industry, Female infertility, Genetic Variation, Obstetrics and Gynecology, DNA, Exons, Luteinizing Hormone, medicine.disease, Polycystic ovary, Reproductive Medicine, Mutation, Female, Restriction fragment length polymorphism, business, Infertility, Female, Polymorphism, Restriction Fragment Length
Abstract: Objective: To investigate whether the newly described G 1502 to A 1502 mutation in exon 3 of the LH β-subunit gene, causing the amino acid substitution of Ser 102 for Gly 102 , is related to female infertility. Design: Screening of fertile and infertile women for the G 1502 to A 1502 mutation in the LH β-subunit gene. Setting: Clinics and laboratories of the National University Hospital obstetrics and gynecology department, Singapore. Patient(s): Two hundred twelve healthy fertile women; 40 infertile women with menstrual disorders, polycystic ovary syndrome, and endometriosis; and 12 women with idiopathic infertility. Intervention(s): Exon 3 of the LH β-subunit gene was analyzed using polymerase chain reaction (PCR), restriction fragment length polymorphism (RFLP), and PCR-mediated direct DNA sequencing. Main Outcome Measure(s): The PCR products of patients were analyzed by RFLP, and the results were compared with those of fertile controls. DNA sequencing radiographs were compared between two mutation-bearing patients and four controls. Result(s): The mutation was identified in only two infertile women with endometriosis; other women studied were found to be negative for this mutation. Conclusion(s): The missense mutation in the LH β-subunit gene may be implicated in female infertility, possibly endometriosis-associated infertility in some women.
Published: 1998
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13. Responses of polycystic ovarian syndrome and related variants to low-dose follicle stimulating hormone

Author: J. Kumar, L.S. Teo, S. C. Ng, Eu Leong Yong, Chan Cl, and S. S. Ratnam
Subjects: Adult, endocrine system, medicine.medical_specialty, endocrine system diseases, medicine.drug_class, medicine.medical_treatment, Ovary, Follicle-stimulating hormone, Ovulation Induction, Pregnancy, Internal medicine, Follicular phase, medicine, Humans, business.industry, Female infertility, nutritional and metabolic diseases, Obstetrics and Gynecology, General Medicine, medicine.disease, Polycystic ovary, female genital diseases and pregnancy complications, Treatment Outcome, Endocrinology, medicine.anatomical_structure, Female, Ovulation induction, Follicle Stimulating Hormone, Gonadotropin, business, Infertility, Female, Polycystic Ovary Syndrome
Abstract: Objective: To determine whether patients with classical polycystic ovarian syndrome (PCOS) respond differently to low-dose FSH therapy in comparison with anovulatory patients (PCOS-like) where only some features of PCOS are present. Methods: Two groups of patients were studied. The PCOS group (25 patients, 51 cycles) and the PCOS-like group (38 patients, 57 cycles) were treated with the same protocol of purified FSH, commencing with an initial dosage of 75 IU/day and increasing by 37.5 IU/day after 14 days, where necessary. Estradiol levels and ultrasonographic evidence of follicular development were used for monitoring. Results: PCOS patients required more ampules of FSH, needed more days of gonadotropin stimulation, secreted higher levels of E 2 and had increased numbers of intermediate follicles compared to the PCOS-like group. Conclusions: This study demonstrated significant differences between PCOS and other PCOS-like conditions when treated with low-dose FSH. Classification of the subvariants of PCOS may have therapeutic implications.
Published: 1997
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14. ART practice in Singapore

Author: S. Emmanuel, Chan Cl, Ariff Bongso, S. C. Ng, J. Kumar, and S. S. Ratnam
Subjects: medicine.medical_specialty, Data collection, business.industry, Advisory committee, MEDLINE, Reproductive medicine, Obstetrics and Gynecology, General Medicine, Reproductive Medicine, Family medicine, Genetics, Medicine, business, Genetics (clinical), Health policy, Developmental Biology
Abstract: ART practice in Singapore is monitored by the MOH, with guidance from an Advisory Committee on HRE. All centers and practitioners must be licensed. Data collection is by means of three forms. Based on the submissions, the averages for all centers in Singapore for the 5 years 1990 to 1995 were as follows: clinical pregnancies averaged 16.4% per cycle and 22.6% per replacement, and take-home baby rates averaged 11.5% per cycle and 15.9% per replacement.
Published: 1996
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15. Chronic low-dose follicle-stimulating hormone compared with clomiphene/human menopausal gonadotropin for induction of ovulation

Author: S. C. Ng, L. S. Teo, Chan Cl, J. Kumar, Eu Leong Yong, and S. S. Ratnam
Subjects: Adult, endocrine system, medicine.medical_specialty, Menotropins, medicine.drug_class, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, media_common.quotation_subject, Chorionic Gonadotropin, Clomiphene, Follicle-stimulating hormone, Endocrinology, Ovarian Follicle, Ovulation Induction, Pregnancy, Internal medicine, medicine, Humans, Ovulation, media_common, biology, Estradiol, business.industry, Ovary, Obstetrics and Gynecology, medicine.disease, Regimen, Treatment Outcome, HMG-CoA reductase, biology.protein, Ovulation induction, Female, Gonadotropin, Follicle Stimulating Hormone, business, hormones, hormone substitutes, and hormone antagonists, Hormone
Abstract: Concurrent administration of clomiphene can reduce the amount of gonadotropins required for induction of ovulation. Recently, follicle-stimulating hormone (FSH) administered in a chronic, low-dose fashion has been reported to give satisfactory pregnancy rates. We compared the conventional clomiphene/human menopausal gonadotropin (hMG) with the chronic, low-dose FSH regimen for induction of ovulation in 87 patients over 110 cycles. The clomiphene/hMG regimen required half the amount of gonadotropin compared to the chronic FSH regimen to achieve follicular maturation. Despite the reduced amount of gonadotropin, the clomiphene/hMG regimen induced a mean fourfold higher level of estradiol production and was associated with significantly greater numbers of large and intermediate-sized follicles compared to the chronic FSH regimen. The proportion of clomiphene/hMG cases with multifollicular development and overstimulation was therefore high (30%). In contrast, the chronic FSH regimen, despite requiring larger amounts of gonadotropin and longer periods of treatment, resulted in unifollicular development, low rates of overstimulation and improved pregnancy rates. We conclude that although clomiphene can reduce the requirement for gonadotropins, the relative safety and effectiveness of the chronic low-dose FSH regimen makes it the method of choice for ovulation induction.
Published: 1997

16. Oral trazodone in the treatment of total secondary impotence in a diabetic patient

Author: Soon-Chye Ng, Shan S. Ratnam, Chan Cl, and P.G. Adaikan
Subjects: Male, Time Factors, Side effect, Urology, medicine.medical_treatment, Priapism, Administration, Oral, Intracavernous injection, Erectile Dysfunction, Oral administration, medicine, Humans, chemistry.chemical_classification, Chemotherapy, business.industry, Trazodone, Middle Aged, medicine.disease, chemistry, Diabetes Mellitus, Type 2, Anesthesia, Antidepressant, business, Tricyclic, medicine.drug
Abstract: The antidepressant trazodone differs in both pharmacological properties and structure from the tricyclic antidepressants and offers some advantages over them in terms of side effects and toxicity. However, there are reports of priapism as a side effect associated with the oral use of trazodone and alpha-adrenoceptor blocking activity was suggested as the mechanism. It is known that the intracavernous injection of alpha-adrenoceptor blocking agents produces erection (Brindley, 1983). We report the effect of oral trazodone in the treatment of impotence.
Published: 1991

17. Spreading-resistance temperature sensor on silicon-on-insulator

Author: Lai, PT, Li, B., Chan, CL, Sin, JKO, Lai, PT, Li, B., Chan, CL, and Sin, JKO
Abstract: A spreading-resistance temperature (SRT) sensor is fabricated on silicon-on-insulator (SOI) substrate and achieves promising characteristics as compared with similar SRT sensor on hulk silicon wafer. Moreover, experimental results show that the maximum operating temperature of thin-film (1.2 mu m) SOI SRT sensor can reach 450 degrees C, much higher than 350 degrees C of thick-film (10 mu m) SOI SRT sensor under the same current level, With complete oxide isolation, this sensor structure can be potentially used in low-power integrated sensors operating at temperatures as high as 450 degrees C.
Published: 1999

18. Pregnancies after fertilization and cleavage in human coculture

Author: Siew Bee Soon, Y. C. Wong, Shan S. Ratnam, Ariff Bongso, Soon-Chye Ng, Chan Cl, C. Anandakumar, Sharath Devendra, Victor H.H. Goh, Shivani Vasuthevan, and Chui Yee Fong
Subjects: Embryology, medicine.medical_specialty, Reproductive medicine, Obstetrics and Gynecology, General Medicine, Biology, Cleavage (embryo), Andrology, Human fertilization, Reproductive Medicine, Genetics, medicine, Genetics (clinical), Developmental Biology
Published: 1991
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19. Mining association language patterns using a distributional semantic model for negative life event classification.

Author: Yu LC, Chan CL, Lin CC, and Lin IC
Published: 2011

20. Estimated prevalence of orthopaedic fractures in Taiwan-A cross-sectional study based on nationwide insurance data.

Author: Yang NP, Chan CL, Yu IL, Lee CY, and Chou P
Published: 2010
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21. What does psychological autopsy study tell us about charcoal burning suicide--a new and contagious method in Asia?

Author: Chan SS, Chiu HF, Chen EY, Chan WS, Wong PW, Chan CL, Law YW, and Yip PS
Abstract: Charcoal burning suicides in Hong Kong between 2002-2004 in the 15 to 59-year-old age group were investigated using the psychological autopsy method. The psychopathological profiles of charcoal burning suicides (N = 53) were compared against 'other suicides' (N = 97). The two groups did not differ significantly in the prevalence of DSM-IV axis I diagnoses with the exception of schizophrenic spectrum disorder which was less frequently associated with charcoal burning suicides. Score on 'neuroticism' in the NEO-five Factor Inventory (NEO-FFI) was significantly higher in victims of charcoal burning suicide. There was also a trend toward higher score on 'conscientiousness' in the NEO-FFI among charcoal burners than victims of other suicide. [ABSTRACT FROM AUTHOR]
Published: 2009
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22. The effect of psychotherapy added to pharmacotherapy on cortisol responses in outpatients with major depressive disorder.

Author: Yang TT, Hsiao FH, Wang KC, Ng SM, Ho RT, Chan CL, Lai YM, and Chen YT
Published: 2009
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23. Psychometric properties of the Chinese version of the 25-item National Eye Institute Visual Function Questionnaire.

Author: Wang CW, Chan CL, and Jin HY
Published: 2008
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24. Survey on death and dying in Hong Kong: attitudes, beliefs, and preferred end-of-life care.

Author: Mjelde-Mossey LA and Chan CL
Abstract: Social Workers in end-of-life and palliative care have a particular opportunity to ease the dying process by providing culturally appropriate services to the dying and their families. In today's multicultural social environment, with an ever-increasing immigrant population, social workers are challenged to be knowledgeable about diverse cultures. Recently, a forum of health care professionals and social workers in Hong Kong conducted a survey of the general population to assess death and dying attitudes, beliefs, and preferences for end-of-life care. Four-hundred-thirty Hong Kong Chinese participated in a telephone interview. Responses were compared by gender. The survey results not only contribute to an understanding of Hong Kong Chinese, but can inform social workers who practice with Chinese immigrants to the United States. [ABSTRACT FROM AUTHOR]
Published: 2007
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25. Socio-economic and psychological correlates of suicidality among Hong Kong working-age adults: results from a population-based survey.

Author: Liu KY, Chen EY, Chan CL, Lee DT, Law YW, Conwell Y, and Yip PS
Abstract: Background. The global toll of suicide is estimated to be one million lives per year, which exceeded the number of deaths by homicide and war combined. A key step to suicide prevention is to prevent less serious suicidal behaviour to preclude more lethal outcomes. Although 61% of the world's suicides take place in Asia and the suicide rates among middle age groups have been increasing since the economic crisis in many Asian countries, population-based studies of suicidal behaviour among working-age adults in non-western communities are scarce.Method. Data from a population-based survey with 2015 participants were used to estimate the prevalence of suicidal ideation and behaviour among the working-age population in Hong Kong, and to study the associated socio-economic and psychological correlates. We focused particularly on potential modulating factors between life-event-related factors and suicidal ideation.Results. Six per cent of the Hong Kong population aged 20-59 years considered suicide in the past year, while 1.4% attempted suicide. Hopelessness, reasons for living, and reluctance to seek help from family and friends had direct association with past-year suicidal ideation. Reasons for living were found to moderate the effect of perceived stress on suicidal ideation.Conclusions. Suicidality is a multi-faceted problem that calls for a multi-sectored, multi-layered approach to prevention. Prevention programmes can work on modulating factors such as reasons for living to reduce suicidal risk in working-age adults. [ABSTRACT FROM AUTHOR]
Published: 2006
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26. The Strength-Focused and Meaning-Oriented Approach to Resilience and Transformation (SMART): a body-mind-spirit approach to trauma management.

Author: Chan CL, Chan THY, and Ng SM
Abstract: This article introduces the Strength-focused and Meaning-oriented Approach to Resilience and Transformation (SMART) as a model of crisis intervention, which aims at discovering inner strengths through meaning reconstruction. Limitations of conventional crisis management and current findings in post-traumatic growth research are discussed. Instead of adopting a pathological framework, the SMART approach holds a holistic view of health, employs facilitative strategies, and promotes dynamic coping. Intervention components include Eastern spiritual teachings, physical techniques such as yoga and meditation, and psycho-education that promotes meaning reconstruction. Efficacy of the SMART model is assessed with reference to two pilot studies conducted in Hong Kong at the time when the SARS pandemic caused widespread fear and anxiety in the community. Response to potential criticisms of the SMART model is attempted. [ABSTRACT FROM AUTHOR]
Published: 2006
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27. Group debriefing for people with chronic diseases during the SARS pandemic: Strength-Focused and Meaning-Oriented Approach for Resilience and Transformation (SMART)

Author: Ng SM, Chan THY, Chan CL, Lee AM, Yau JKY, Chan CHY, and Lau J
Abstract: This study presented preliminary results on the efficacy of a novel group debriefing model called Strength-Focused and Meaning-Oriented Approach for Resilience and Transformation (SMART). The SMART debriefing (1) aimed at boosting resilience and catalyzing transformation among persons undergoing stressful events, (2) adopted a growth-oriented and holistic approach of health promotion, and (3) employed methods drawn from various indigenous sources (e.g. Asian philosophies and Traditional Chinese Medicine). Participants (N=51) were people with chronic diseases recruited about 1 month (August 2003) after the Severe Acute Respiratory Syndrome (SARS) outbreak was eventually under control, after causing widespread panic in Hong Kong. After the one-day group debriefing, participants showed significant decrease in depression level, as measured by Brief Symptom Inventory (Derogatis & Melisaratos, 1983, Psychological Medicine, 13(3), 595-605) and changes in cognitive appraisal towards SARS. Such changes were sustained in a 1-month follow-up. Clinical implications and directions for further study were discussed. [ABSTRACT FROM AUTHOR]
Published: 2006
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28. Women coping with divorce in the unique sociocultural context of Hong Kong.

Author: Hung S, Kung WW, and Chan CL
Abstract: From a stress and coping perspective, this qualitative study examined the impact of Hong Kong's sociocultural context on divorce experience of 35 women. Under the bind of traditional Chinese values and Western ideals, divorce was experienced as a threat to normal life and an oppression leading to economic hardship and a loss of self-identity. However, these women were hardy and creative in coping, drawing assets from both Chinese and Western cultures as they justified the divorce, assumed the role of 'tragic heroine,' endorsed notions of predestination and multiple lives, valued single parenthood, and reconstructed positive meanings of divorce. Implications for social work practice were discussed. [ABSTRACT FROM AUTHOR]
Published: 2003

29. Childbirth expectations of Chinese first-time pregnant women.

Author: Ip WY, Chien WT, and Chan CL
Subjects: CHILDBIRTH, PREGNANCY, QUESTIONNAIRES
Abstract: Background. This topic had not been researched previously and the information gained could have implications for midwives working with Chinese women everywhere. Aims. To explore the specific childbirth expectations of Hong Kong Chinese first-time pregnant women. Methods. This was a cross-sectional descriptive survey study and a Chinese version of the Childbirth Expectations Questionnaire was used to collect data. The sample consisted of 186 first-time pregnant women who first attended the antenatal clinic at a large public hospital in a major geographical region of Hong Kong. Results. Results showed that the Chinese pregnant women, the majority of who had not attended childbirth education classes, had high expectations of support from both their partners and midwives during labour and delivery. Conversely, expectations toward their own ability to cope with pain were relatively low. In addition, the pregnant women expressed concerns about the severity of labour pain and indicated low expectations about minimal use of medical interventions during labour. Conclusions. This study results add to the existing literature about childbirth expectations of first-time pregnant Hong Kong Chinese women. Midwife educators should incorporate the findings into childbirth education classes to help pregnant women develop realistic and positive expectations. [ABSTRACT FROM AUTHOR]
Published: 2003
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30. Adoption in utero is the wrong term

Author: Soon-Chye Ng, S. S. Ratnam, Chan Cl, and B. M. Marshall
Subjects: medicine.medical_specialty, Obstetrics, In utero, business.industry, General Engineering, medicine, General Earth and Planetary Sciences, General Medicine, Telecommunications, business, Embryo transfer, General Environmental Science, Term (time)
Published: 1992
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31. Toward a Deeper Understanding of Disability: Physical Therapy Educators’ Reflections

Author: Chan, Clarence, Engel, Debra, and Ross, Jacqueline
Published: 2015

32. Commentary on Liu JE, Mok E & Wong T (2006). Caring in nursing: investigating the meaning of caring from the perspective of cancer patients in Beijing, China.

Author: Chan CL and Leung PP
Published: 2007
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33. Birth from replacement of frozen-thawed embryos after failure of gamete intra-fallopian transfer: a successful pregnancy case

Author: S. C. Ng, M.P.R. Hamilton, T. A. Bongso, S. S. Ratnam, Chan Cl, and Patrick Wong
Subjects: Adult, Male, medicine.medical_specialty, medicine.medical_treatment, Twins, Biology, Andrology, Embryo cryopreservation, Pregnancy, Freezing, medicine, Humans, Gamete intrafallopian transfer, Gynecology, Infant, Newborn, Obstetrics and Gynecology, Embryo, medicine.disease, Successful pregnancy, Embryo, Mammalian, Infant newborn, Sperm, Gamete Intrafallopian Transfer, medicine.anatomical_structure, Gamete, Female, Tissue Preservation, Pregnancy, Multiple
Abstract: The patient was 8 years subfertile and had failed other forms of treatment when she was enrolled in the GIFT program. Of the total of 16 oocytes recovered 4 were transferred and the remaining 12 inseminated with her husband's sperm. Four resulting embryos were frozen. When she did not conceive, the 4 embryos were thawed 3 months later and replaced into her. She conceived and recently delivered a pair of twins. The protocol will be discussed in detail. Cryopreservation of embryos therefore may increase the patient's chance of pregnancy in a GIFT program.
Published: 1989

34. Virtual laboratory development for teaching power electronics

Author: Sutanto, D., Cheung, Cn, Chan, Cl, and Eric Ka Wai CHENG

35. An unusual outbreak of hypoglycemia--a correction.

Author: Kao SL, Chan CL, Tan B, Lim CC, Dalan R, Gardner D, Pratt E, Lee M, and Lee KO
Published: 2009
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36. Remanipulation of forearm fractures in children

Author: Chan, Clayton F G, Meads, Bryce M, and Nicol, Richard O
Published: 1997

37. Model-based Cross-correlation Search for Gravitational Waves from the Low-mass X-Ray Binary Scorpius X-1 in LIGO O3 Data

Author: The LIGO Scientific Collaboration, the Virgo Collaboration, the KAGRA Collaboration, Abbott, R., Abe, H., Acernese, F., Ackley, K., Adhicary, S., Adhikari, N., Adhikari, R. X., Adkins, V. K., Adya, V. B., Affeldt, C., Agarwal, D., Agathos, M., Aguiar, O. D., Aiello, L., Ain, A., Ajith, P., Akutsu, T., Albanesi, S., Alfaidi, R. A., Alléné, C., Allocca, A., Altin, P. A., Amato, A., Anand, S., Ananyeva, A., Anderson, S. B., Anderson, W. G., Ando, M., Andrade, T., Andres, N., Andrés-Carcasona, M., Andrić, T., Ansoldi, S., Antelis, J. M., Antier, S., Apostolatos, T., Appavuravther, E. Z., Appert, S., Apple, S. K., Arai, K., Araya, A., Araya, M. C., Areeda, J. S., Arène, M., Aritomi, N., Arnaud, N., Arogeti, M., Aronson, S. M., Asada, H., Ashton, G., Aso, Y., Assiduo, M., Melo, S. Assis de Souza, Aston, S. M., Astone, P., Aubin, F., AultONeal, K., Babak, S., Badaracco, F., Badger, C., Bae, S., Bae, Y., Bagnasco, S., Bai, Y., Baier, J. G., Baird, J., Bajpai, R., Baka, T., Ball, M., Ballardin, G., Ballmer, S. W., Baltus, G., Banagiri, S., Banerjee, B., Bankar, D., Barayoga, J. C., Barish, B. C., Barker, D., Barneo, P., Barone, F., Barr, B., Barsotti, L., Barsuglia, M., Barta, D., Bartlett, J., Barton, M. A., Bartos, I., Basak, S., Bassiri, R., Basti, A., Bawaj, M., Bayley, J. C., Bazzan, M., Bécsy, B., Bedakihale, V. M., Beirnaert, F., Bejger, M., Belahcene, I., Bell, A. S., Benedetto, V., Beniwal, D., Benoit, W., Bentley, J. D., BenYaala, M., Bera, S., Berbel, M., Bergamin, F., Berger, B. K., Bernuzzi, S., Beroiz, M., Bersanetti, D., Bertolini, A., Betzwieser, J., Beveridge, D., Bhandare, R., Bhandari, A. V., Bhardwaj, U., Bhatt, R., Bhattacharjee, D., Bhaumik, S., Bianchi, A., Bilenko, I. A., Bilicki, M., Billingsley, G., Bini, S., Birnholtz, O., Biscans, S., Bischi, M., Biscoveanu, S., Bisht, A., Biswas, B., Bitossi, M., Bizouard, M. -A., Blackburn, J. K., Blair, C. D., Blair, D. G., Blair, R. M., Bobba, F., Bode, N., Boër, M., Bogaert, G., Boldrini, M., Bolingbroke, G. N., Bonavena, L. D., Bondarescu, R., Bondu, F., Bonilla, E., Bonnand, R., Booker, P., Bork, R., Boschi, V., Bose, N., Bose, S., Bossilkov, V., Boudart, V., Bouffanais, Y., Bozzi, A., Bradaschia, C., Brady, P. R., Bramley, A., Branch, A., Branchesi, M., Brau, J. E., Breschi, M., Briant, T., Briggs, J. H., Brillet, A., Brinkmann, M., Brockill, P., Brooks, A. F., Brooks, J., Brown, D. D., Brunett, S., Bruno, G., Bruntz, R., Bryant, J., Bucci, F., Buchanan, J., Bulik, T., Bulten, H. J., Buonanno, A., Burtnyk, K., Buscicchio, R., Buskulic, D., Buy, C., Byer, R. L., Davies, G. S. Cabourn, Cabras, G., Cabrita, R., Cadonati, L., Cagnoli, G., Cahillane, C., Bustillo, J. Calderón, Callaghan, J. D., Callister, T. A., Calloni, E., Camp, J. B., Canepa, M., Caneva, G., Cannavacciuolo, M., Cannon, K. C., Cao, H., Cao, Z., Capistran, L. A., Capocasa, E., Capote, E., Carapella, G., Carbognani, F., Carlassara, M., Carlin, J. B., Carpinelli, M., Carrillo, G., Carter, J. J., Carullo, G., Diaz, J. Casanueva, Casentini, C., Castaldi, G., Caudill, S., Cavaglià, M., Cavalier, F., Cavalieri, R., Cella, G., Cerdá-Durán, P., Cesarini, E., Chaibi, W., Chakalis, W., Subrahmanya, S. Chalathadka, Champion, E., Chan, C. -H., Chan, C., Chan, C. L., Chan, K., Chan, M., Chandra, K., Chang, I. P., Chang, W., Chanial, P., Chao, S., Chapman-Bird, C., Charlton, P., Chassande-Mottin, E., Chatterjee, C., Chatterjee, Debarati, Chatterjee, Deep, Chaturvedi, M., Chaty, S., Chen, C., Chen, D., Chen, H. Y., Chen, J., Chen, K., Chen, X., Chen, Y. -B., Chen, Y. -R., Chen, Y., Cheng, H., Chessa, P., Cheung, H. Y., Chia, H. Y., Chiadini, F., Chiang, C-Y., Chiarini, G., Chierici, R., Chincarini, A., Chiofalo, M. L., Chiummo, A., Choudhary, R. K., Choudhary, S., Christensen, N., Chu, Q., Chu, Y-K., Chua, S. S. Y., Chung, K. W., Ciani, G., Ciecielag, P., Cieślar, M., Cifaldi, M., Ciobanu, A. A., Ciolfi, R., Clara, F., Clark, J. A., Clarke, T. A., Clearwater, P., Clesse, S., Cleva, F., Coccia, E., Codazzo, E., Cohadon, P. -F., Cohen, D. E., Colleoni, M., Collette, C. G., Colombo, A., Colpi, M., Compton, C. M., Conti, L., Cooper, S. J., Corban, P., Corbitt, T. R., Cordero-Carrión, I., Corezzi, S., Cornish, N. J., Corsi, A., Cortese, S., Coschizza, A. C., Cotesta, R., Cottingham, R., Coughlin, M. W., Coulon, J. -P., Countryman, S. T., Cousins, B., Couvares, P., Coward, D. M., Cowart, M. J., Coyne, D. C., Coyne, R., Craig, K., Creighton, J. D. E., Creighton, T. D., Criswell, A. W., Croquette, M., Crowder, S. G., Cudell, J. R., Cullen, T. J., Cumming, A., Cummings, R., Cuoco, E., Curyło, M., Dabadie, P., Canton, T. Dal, Dall'Osso, S., Dálya, G., Dana, A., D'Angelo, B., Danilishin, S., D'Antonio, S., Danzmann, K., Darsow-Fromm, C., Dasgupta, A., Datrier, L. E. H., Datta, Sayantani, Dattilo, V., Dave, I., Davier, M., Davis, D., Davis, M. C., Daw, E. J., Dax, M., DeBra, D., Deenadayalan, M., Degallaix, J., De Laurentis, M., Deléglise, S., Del Favero, V., De Lillo, F., De Lillo, N., Dell'Aquila, D., Del Pozzo, W., De Matteis, F., D'Emilio, V., Demos, N., Dent, T., Depasse, A., De Pietri, R., De Rosa, R., De Rossi, C., DeSalvo, R., De Simone, R., Dhurandhar, S., Diab, R., Díaz, M. C., Didio, N. A., Dietrich, T., Di Fiore, L., Di Fronzo, C., Di Giorgio, C., Di Giovanni, F., Di Giovanni, M., Di Girolamo, T., Diksha, D., Di Lieto, A., Di Michele, A., Di Pace, S., Di Palma, I., Di Renzo, F., Divakarla, A. K., Dmitriev, A., Doctor, Z., Doleva, P. P., Donahue, L., D'Onofrio, L., Donovan, F., Dooley, K. L., Dooney, T., Doravari, S., Dorosh, O., Drago, M., Driggers, J. C., Drori, Y., Ducoin, J. -G., Dunn, L., Dupletsa, U., Durante, O., D'Urso, D., Duverne, P. -A., Dwyer, S. E., Eassa, C., Easter, P. J., Ebersold, M., Eckhardt, T., Eddolls, G., Edelman, B., Edo, T. B., Edy, O., Effler, A., Eguchi, S., Eichholz, J., Eikenberry, S. S., Eisenmann, M., Eisenstein, R. A., Ejlli, A., Engelby, E., Enomoto, Y., Errico, L., Essick, R. C., Estellés, H., Estevez, D., Etzel, T., Evans, M., Evans, T. M., Evstafyeva, T., Ewing, B. E., Fabrizi, F., Faedi, F., Fafone, V., Fair, H., Fairhurst, S., Fan, P. C., Farah, A. M., Farr, B., Farr, W. M., Favaro, G., Favata, M., Fays, M., Fazio, M., Feicht, J., Fejer, M. M., Fenyvesi, E., Ferguson, D. L., Fernandez-Galiana, A., Ferrante, I., Ferreira, T. A., Fidecaro, F., Figura, P., Fiori, A., Fiori, I., Fishbach, M., Fisher, R. P., Fittipaldi, R., Fiumara, V., Flaminio, R., Floden, E., Fong, H. K., Font, J. A., Fornal, B., Forsyth, P. W. F., Franke, A., Frasca, S., Frasconi, F., Freed, J. P., Frei, Z., Freise, A., Freitas, O., Frey, R., Fritschel, P., Frolov, V. V., Fronzé, G. G., Fujii, Y., Fujikawa, Y., Fujimoto, Y., Fulda, P., Fyffe, M., Gabbard, H. A., Gabella, W. E., Gadre, B. U., Gair, J. R., Gais, J., Galaudage, S., Gamba, R., Ganapathy, D., Ganguly, A., Gao, D. -F., Gao, D., Gaonkar, S. G., Garaventa, B., García-Núñez, C., García-Quirós, C., Gardner, K. A., Gargiulo, J., Garufi, F., Gasbarra, C., Gateley, B., Gayathri, V., Ge, G. -G., Gemme, G., Gennai, A., George, J., Gerberding, O., Gergely, L., Ghonge, S., Ghosh, Abhirup, Ghosh, Archisman, Ghosh, Shaon, Ghosh, Shrobana, Ghosh, Tathagata, Giacoppo, L., Giaime, J. A., Giardina, K. D., Gibson, D. R., Gier, C., Giri, P., Gissi, F., Gkaitatzis, S., Glanzer, J., Gleckl, A. E., Godoy, F. G., Godwin, P., Goetz, E., Goetz, R., Golomb, J., Goncharov, B., González, G., Gosselin, M., Gouaty, R., Gould, D. W., Goyal, S., Grace, B., Grado, A., Graham, V., Granata, M., Granata, V., Gras, S., Grassia, P., Gray, C., Gray, R., Greco, G., Green, A. C., Green, R., Gretarsson, A. M., Gretarsson, E. M., Griffith, D., Griffiths, W. L., Griggs, H. L., Grignani, G., Grimaldi, A., Grimm, S. J., Grote, H., Grunewald, S., Gruson, A. S., Guerra, D., Guidi, G. M., Guimaraes, A. R., Gulati, H. K., Gulminelli, F., Gunny, A. M., Guo, H. -K., Guo, Y., Gupta, Anchal, Gupta, Anuradha, Gupta, P., Gupta, S. K., Gurs, J., Gustafson, R., Gutierrez, N., Guzman, F., Ha, S., Hadiputrawan, I. P. W., Haegel, L., Haino, S., Halim, O., Hall, E. D., Hamilton, E. Z., Hammond, G., Han, W. -B., Haney, M., Hanks, J., Hanna, C., Hannam, M. D., Hannuksela, O., Hansen, H., Hanson, J., Harada, R., Harder, T., Haris, K., Harms, J., Harry, G. M., Harry, I. W., Hartwig, D., Hasegawa, K., Haskell, B., Haster, C. -J., Hathaway, J. S., Hattori, K., Haughian, K., Hayakawa, H., Hayama, K., Hayes, F. J., Healy, J., Heidmann, A., Heidt, A., Heintze, M. C., Heinze, J., Heinzel, J., Heitmann, H., Hellman, F., Hello, P., Helmling-Cornell, A. F., Hemming, G., Hendry, M., Heng, I. S., Hennes, E., Hennig, J. -S., Hennig, M., Henshaw, C., Hernandez, A. G., Vivanco, F. Hernandez, Heurs, M., Hewitt, A. L., Higginbotham, S., Hild, S., Hill, P., Himemoto, Y., Hines, A. S., Hirata, N., Hirose, C., Ho, T-C., Hochheim, S., Hofman, D., Hohmann, J. N., Holcomb, D. G., Holland, N. A., Hollows, I. J., Holmes, Z. J., Holt, K., Holz, D. E., Hong, Q., Hough, J., Hourihane, S., Howell, D., Howell, E. J., Hoy, C. G., Hoyland, D., Hreibi, A., Hsieh, B-H., Hsieh, H-F., Hsiung, C., Huang, H-Y., Huang, P., Huang, Y-C., Huang, Y. -J., Huang, Y., Hübner, M. T., Huddart, A. D., Hughey, B., Hui, D. C. Y., Hui, V., Husa, S., Huttner, S. H., Huxford, R., Huynh-Dinh, T., Hyland, J., Iandolo, G. A., Ide, S., Idzkowski, B., Iess, A., Inayoshi, K., Inoue, Y., Iosif, P., Irwin, J., Gupta, Ish, Isi, M., Ito, K., Itoh, Y., Iyer, B. R., JaberianHamedan, V., Jacqmin, T., Jacquet, P. -E., Jadhav, S. J., Jadhav, S. P., Jain, T., James, A. L., Jan, A. Z., Jani, K., Janquart, J., Janssens, K., Janthalur, N. N., Jaranowski, P., Jariwala, D., Jarov, S., Jaume, R., Jenkins, A. C., Jenner, K., Jeon, C., Jia, W., Jiang, J., Jin, H. -B., Johns, G. R., Johnston, R., Johny, N., Jones, A. W., Jones, D. I., Jones, P., Jones, R., Joshi, P., Ju, L., Jung, K., Jung, P., Junker, J., Juste, V., Kaihotsu, K., Kajita, T., Kakizaki, M., Kalaghatgi, C., Kalogera, V., Kamai, B., Kamiizumi, M., Kanda, N., Kandhasamy, S., Kang, G., Kanner, J. B., Kao, Y., Kapadia, S. J., Kapasi, D. P., Karat, S., Karathanasis, C., Karki, S., Kashyap, R., Kasprzack, M., Kastaun, W., Kato, T., Katsanevas, S., Katsavounidis, E., Katzman, W., Kaur, T., Kawabe, K., Kawaguchi, K., Kéfélian, F., Keitel, D., Key, J. S., Khadka, S., Khalili, F. Y., Khan, S., Khanam, T., Khazanov, E. A., Khetan, N., Khursheed, M., Kijbunchoo, N., Kim, C., Kim, J. C., Kim, J., Kim, K., Kim, P., Kim, W. S., Kim, Y. -M., Kimball, C., Kimura, N., King, B., Kinley-Hanlon, M., Kirchhoff, R., Kissel, J. S., Klimenko, S., Klinger, T., Knee, A. M., Knust, N., Kobayashi, Y., Koch, P., Koehlenbeck, S. M., Koekoek, G., Kohri, K., Kokeyama, K., Koley, S., Kolitsidou, P., Kolstein, M., Kondrashov, V., Kong, A. K. H., Kontos, A., Korobko, M., Kossak, R. V., Kovalam, M., Koyama, N., Kozak, D. B., Kozakai, C., Kranzhoff, L., Kringel, V., Krishnendu, N. V., Królak, A., Kuehn, G., Kuijer, P., Kulkarni, S., Kumar, A., Kumar, Praveen, Kumar, Prayush, Kumar, Rahul, Kumar, Rakesh, Kume, J., Kuns, K., Kuromiya, Y., Kuroyanagi, S., Kuwahara, S., Kwak, K., Lacaille, G., Lagabbe, P., Laghi, D., Lalande, E., Lalleman, M., Lamberts, A., Landry, M., Lane, B. B., Lang, R. N., Lange, J., Lantz, B., La Rosa, I., Lartaux-Vollard, A., Lasky, P. D., Lawrence, J., Laxen, M., Lazzarini, A., Lazzaro, C., Leaci, P., Leavey, S., LeBohec, S., Lecoeuche, Y. K., Lee, E., Lee, H. M., Lee, H. W., Lee, K., Lee, R., Legred, I. N., Lehmann, J., Lemaître, A., Lenti, M., Leonardi, M., Leonova, E., Leroy, N., Letendre, N., Levesque, C., Levin, Y., Leviton, J. N., Leyde, K., Li, A. K. Y., Li, B., Li, K. L., Li, P., Li, T. G. F., Li, X., Lin, C-Y., Lin, E. T., Lin, F-K., Lin, F-L., Lin, H. L., Lin, L. C. -C., Linde, F., Linker, S. D., Littenberg, T. B., Liu, G. C., Liu, J., Liu, X., Llamas, F., Lo, R. K. L., Lo, T., London, L. T., Longo, A., Lopez, D., Portilla, M. Lopez, Lorenzini, M., Loriette, V., Lormand, M., Losurdo, G., Lott, T. P., Lough, J. D., Lousto, C. O., Lovelace, G., Lowry, M. J., Lucaccioni, J. F., Lück, H., Lumaca, D., Lundgren, A. P., Lung, Y., Luo, L. -W., Lussier, A. W., Lynam, J. E., Ma'arif, M., Macas, R., MacInnis, M., Macleod, D. M., MacMillan, I. A. O., Macquet, A., Hernandez, I. Magaña, Magazzù, C., Magee, R. M., Maggiore, R., Magnozzi, M., Mahesh, S., Majorana, E., Makarem, C. N., Maksimovic, I., Maliakal, S., Malik, A., Man, N., Mandic, V., Mangano, V., Mannix, B. R., Mansell, G. L., Mansingh, G., Manske, M., Mantovani, M., Mapelli, M., Marchesoni, F., Pina, D. Marín, Marion, F., Mark, Z., Márka, S., Márka, Z., Markakis, C., Markosyan, A. 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Mukund, N, Mullavey, A, Munch, J, Muñiz, E, Murray, P, Muusse, S, Nadji, S, Nagano, K, Nagar, A, Nagar, T, Nakamura, K, Nakano, H, Nakano, M, Nakayama, Y, Napolano, V, Nardecchia, I, Narikawa, T, Narola, H, Naticchioni, L, Nayak, R, Neil, B, Neilson, J, Nelson, A, Nelson, T, Nery, M, Neubauer, P, Neunzert, A, Ng, K, Ng, S, Nguyen, C, Nguyen, P, Nguyen, T, Nguyen Quynh, L, Ni, J, Ni, W, Nichols, S, Nieradka, G, Nishimoto, T, Nishizawa, A, Nissanke, S, Nitoglia, E, Niu, W, Nocera, F, Norman, M, North, C, Notte, J, Novak, J, Nozaki, S, Nurbek, G, Nuttall, L, Obayashi, Y, Oberling, J, O'Brien, B, O'Dell, J, Oelker, E, Oertel, M, Ogaki, W, Oganesyan, G, Oh, J, Oh, K, Oh, S, O'Hanlon, T, Ohashi, M, Ohashi, T, Ohkawa, M, Ohme, F, Ohta, H, Okutani, Y, Oliveri, R, Olivetto, C, Oohara, K, Oram, R, O'Reilly, B, Ormiston, R, Ormsby, N, Orselli, M, O'Shaughnessy, R, O'Shea, E, Oshino, S, Ossokine, S, Osthelder, C, Otabe, S, Ottaway, D, Overmier, H, Pace, A, Pagano, G, Pagano, R, Pagliaroli, G, Pai, 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Walle, A, van Dongen, J, van Haevermaet, H, van Heijningen, J, Vanosky, J, van Putten, M, van Ranst, Z, van Remortel, N, Vardaro, M, Vargas, A, Varma, V, Vasúth, M, Vecchio, A, Vedovato, G, Veitch, J, Veitch, P, Venneberg, J, Venugopalan, G, Verdier, P, Verkindt, D, Verma, P, Verma, Y, Vermeulen, S, Veske, D, Vetrano, F, Viceré, A, Vidyant, S, Viets, A, Vijaykumar, A, Villa-Ortega, V, Vinet, J, Virtuoso, A, Vitale, S, Vocca, H, von Reis, E, von Wrangel, J, Vorvick, C, Vyatchanin, S, Wade, L, Wade, M, Wagner, K, Walet, R, Walker, M, Wallace, G, Wallace, L, Wang, J, Wang, W, Ward, R, Warner, J, Was, M, Washimi, T, Washington, N, Watada, K, Watarai, D, Watchi, J, Wayt, K, Weaver, B, Weaving, C, Webster, S, Weinert, M, Weinstein, A, Weiss, R, Weller, C, Weller, R, Wellmann, F, Wen, L, Weßels, P, Wette, K, Whelan, J, White, D, Whiting, B, Whittle, C, Wilk, O, Wilken, D, Williams, C, Williams, D, Williams, M, Williamson, A, Willis, J, Willke, B, Wipf, C, Woan, G, Woehler, J, Wofford, J, Wojtowicz, I, Wong, D, Wong, I, Wright, M, Wu, C, Wu, D, Wu, H, Wysocki, D, Xiao, L, Yadav, N, Yamada, T, Yamamoto, H, Yamamoto, K, Yamamoto, T, Yamashita, K, Yamazaki, R, Yang, F, Yang, K, Yang, L, Yang, Y, Yap, M, Yeeles, D, Yeh, S, Yelikar, A, Yokoyama, J, Yokozawa, T, Yoo, J, Yoshioka, T, Yu, H, Yuzurihara, H, Zadrożny, A, Zanolin, M, Zeidler, S, Zelenova, T, Zendri, J, Zevin, M, Zhan, M, Zhang, H, Zhang, J, Zhang, L, Zhang, R, Zhang, T, Zhang, Y, Zhao, C, Zhao, G, Zhao, Y, Zheng, Y, Zhou, R, Zhu, X, Zhu, Z, Zimmerman, A, Zucker, M, Zweizig, J, The LIGO Scientific Collaboration, the Virgo Collaboration, the KAGRA Collaboration, Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire des deux Infinis de Toulouse (L2IT), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut Lumière Matière [Villeurbanne] (ILM), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de physique corpusculaire de Caen (LPCC), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Joseph Louis LAGRANGE (LAGRANGE), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), (Astro)-Particles Physics, Ackley, K [0000-0002-8648-0767], Adhikari, N [0000-0002-4559-8427], Adhikari, RX [0000-0002-5731-5076], Agathos, M [0000-0002-9072-1121], Aguiar, OD [0000-0002-2139-4390], Aiello, L [0000-0003-2771-8816], Ajith, P [0000-0001-7519-2439], Akutsu, T [0000-0003-0733-7530], Allocca, A [0000-0002-5288-1351], Altin, PA [0000-0001-8193-5825], Amato, A [0000-0001-9557-651X], Anderson, SB [0000-0003-2219-9383], Anderson, WG [0000-0003-0482-5942], Andres, N [0000-0002-5360-943X], Andrés-Carcasona, M [0000-0002-8738-1672], Andrić, T [0000-0002-9277-9773], Antelis, JM 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Subjects: [PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], NEUTRON-STARS, FOS: Physical sciences, O3, General Relativity and Quantum Cosmology (gr-qc), Astronomy & Astrophysics, neutron stars, General Relativity and Quantum Cosmology, gravitational waves, ACCRETION, LIGO, neutron star, Gravitational waves,Gravitational wave astronomy,Neutron stars, Low-mass x-ray binary stars, PRECISION EPHEMERIDES, High-Energy Phenomena and Fundamental Physics, High Energy Astrophysical Phenomena (astro-ph.HE), Settore FIS/01, Gravitational Waves, Gravitational Waves, Scorpius X1, LIGO, O3, Science & Technology, Settore FIS/03, Physics, Scorpius X1, Astronomy and Astrophysics, SDG 10 - Reduced Inequalities, MOUNTAINS, Physics and Astronomy, Space and Planetary Science, 5101 Astronomical Sciences, gravitational wave sources, Physical Sciences, RADIATION, MAXIMUM SPIN FREQUENCY, Astrophysics - High Energy Astrophysical Phenomena, 51 Physical Sciences
Abstract: We present the results of a model-based search for continuous gravitational waves from the low-mass X-ray binary Scorpius X-1 using LIGO detector data from the third observing run of Advanced LIGO, Advanced Virgo and KAGRA. This is a semicoherent search which uses details of the signal model to coherently combine data separated by less than a specified coherence time, which can be adjusted to balance sensitivity with computing cost. The search covered a range of gravitational-wave frequencies from 25Hz to 1600Hz, as well as ranges in orbital speed, frequency and phase determined from observational constraints. No significant detection candidates were found, and upper limits were set as a function of frequency. The most stringent limits, between 100Hz and 200Hz, correspond to an amplitude h0 of about 1e-25 when marginalized isotropically over the unknown inclination angle of the neutron star's rotation axis, or less than 4e-26 assuming the optimal orientation. The sensitivity of this search is now probing amplitudes predicted by models of torque balance equilibrium. For the usual conservative model assuming accretion at the surface of the neutron star, our isotropically-marginalized upper limits are close to the predicted amplitude from about 70Hz to 100Hz; the limits assuming the neutron star spin is aligned with the most likely orbital angular momentum are below the conservative torque balance predictions from 40Hz to 200Hz. Assuming a broader range of accretion models, our direct limits on gravitational-wave amplitude delve into the relevant parameter space over a wide range of frequencies, to 500Hz or more., 19 pages, Open Access Journal PDF
Published: 2023
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38. Constraints on dark photon dark matter using data from LIGO's and Virgo's third observing run

Author: Abbott, R., Abbott, T. D., Acernese, F., Ackley, K., Adams, C., Adhikari, N., Adhikari, R. X., Adya, V. B., Affeldt, C., Agarwal, D., Agathos, M., Agatsuma, K., Aggarwal, N., Aguiar, O. D., Aiello, L., Ain, A., Ajith, P., Akutsu, T., Albanesi, S., Allocca, A., Altin, P. A., Amato, A., Ananyeva, A., Anderson, S. B., Anderson, W. G., Ando, M., Andrade, T., Andres, N., Angelova, V, Ansoldi, S., Antelis, J. M., Antier, S., Appert, S., Arai, Koji, Arai, Koya, Arai, Y., Araki, S., Araya, A., Araya, M. C., Areeda, J. S., Arene, M., Aritomi, N., Arnaud, N., Aronson, S. M., Arun, K. G., Asada, H., Asali, Y., Ashton, G., Aso, Y., Assiduo, M., Aston, S. M., Astone, P., Aubin, F., Austin, C., Babak, S., Badaracco, F., Bader, M. K. M., Badger, C., Bae, S., Bae, Y., Baer, A. M., Bagnasco, S., Bai, Y., Baiotti, L., Baird, J., Bajpai, R., Ball, M., Ballardin, G., Ballmer, S. W., Balsamo, A., Baltus, G., Banagiri, S., Bankar, D., Barayoga, J. C., Barbieri, C., Barish, B. C., Barker, D., Barneo, P., Barone, F., Barr, B., Barsotti, L., Barsuglia, M., Barta, D., Bartlett, J., Barton, M. A., Bartos, I, Bassiri, R., Basti, A., Bawaj, M., Bayley, J. C., Baylor, A. C., Bazzan, M., Becsy, B., Bedakihale, V. M., Bejger, M., Belahcene, I, Benedetto, V, Beniwal, D., Bennett, T. F., Bentley, J. D., Benyaala, M., Bergamin, F., Berger, B. K., Bernuzzi, S., Bersanetti, D., Bertolini, A., Betzwieser, J., Beveridge, D., Are, R., Bhardwaj, U., Bhattacharjee, D., Bhaumik, S., Bilenko, I. A., Billingsley, G., Bini, S., Birney, R., Birnholtz, O., Biscans, S., Bischi, M., Biscoveanu, S., Bisht, A., Biswas, B., Bitossi, M., Bizouard, M-A, Blackburn, J. K., Blair, C. D., Blair, D. G., Blair, R. M., Bobba, F., Bode, N., Boer, M., Bogaert, G., Boldrini, M., Bonavena, L. D., Bondu, F., Bonilla, E., Bonn, Booker, P., Boom, B. A., Bork, R., Boschi, V, Bose, N., Bose, S., Bossilkov, V, Boudart, V, Bouffanais, Y., Bozzi, A., Bradaschia, C., Brady, P. 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H., Huxford, R., Huynh-Dinh, T., Ide, S., Idzkowski, B., Iess, A., Ikenoue, B., Imam, S., Inayoshi, K., Ingram, C., Inoue, Y., Ioka, K., Isi, M., Isleif, K., Ito, K., Itoh, Y., Iyer, B. R., Izumi, K., Jaberianhamedan, V, Jacqmin, T., Jadhav, S. J., Jadhav, S. P., James, A. L., Jan, A. Z., Jani, K., Janquart, J., Janssens, K., Janthalur, N. N., Jaranowski, P., Jariwala, D., Jaume, R., Jenkins, A. C., Jenner, K., Jeon, C., Jeunon, M., Jia, W., Jin, H-B, Johns, G. R., Jones, A. W., Jones, I, Jones, J. D., Jones, P., Jones, R., Jonker, R. J. G., Ju, L., Jung, P., Jung, K., Junker, J., Juste, V, Kaihotsu, K., Kajita, T., Kakizaki, M., Kalaghatgi, Kalogera, V, Kamai, B., Kamiizumi, M., K, A, N., Hasamy, S., Kang, G., Kanner, J. B., Kao, Y., Kapadia, S. J., Kapasi, D. P., Karat, S., Karathanasis, C., Karki, S., Kashyap, R., Kasprzack, M., Kastaun, W., Katsanevas, S., Katsavounidis, E., Katzman, W., Kaur, T., Kawabe, K., Kawaguchi, K., Kawai, N., Kawasaki, T., Kefelian, F., Keitel, D., Key, J. S., Khadka, S., Khalili, F. Y., Khan, S., Khazanov, E. A., Khetan, N., Khursheed, M., Kijbunchoo, N., Kim, C., Kim, J. C., Kim, J., Kim, K., Kim, W. S., Kim, Y-M, Kimball, C., Kimura, N., Kinley-Hanlon, M., Kirchhoff, R., Kissel, J. S., Kita, N., Kitazawa, H., Kleybolte, L., Klimenko, S., Knee, A. M., Knowles, T. D., Knyazev, E., Koch, P., Koekoek, G., Kojima, Y., Kokeyama, K., Koley, S., Kolitsidou, P., Kolstein, M., Komori, K., Kondrashov, V, Kong, A. K. H., Kontos, A., Koper, N., Korobko, M., Kotake, K., Kovalam, M., Kozak, D. 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P., Mitselmakher, G., Mittleman, R., Miyakawa, O., Miyamoto, A., Miyazaki, Y., Miyo, K., Miyoki, S., Geoffrey, Mo, Moguel, E., Mogushi, K., Mohapatra, S. R. P., Mohite, S. R., Molina, I, Molina-Ruiz, M., Mondin, M., Montani, M., Moore, C. J., Moraru, D., Morawski, F., More, A., Moreno, C., Moreno, G., Mori, Y., Morisaki, S., Moriwaki, Y., Mours, B., Mow-Lowry, C. M., Mozzon, S., Muciaccia, F., Mukherjee, Arunava, Mukherjee, D., Mukherjee, Soma, Mukherjee, Subroto, Mukherjee, Suvodip, Mukund, N., Mullavey, A., Munch, J., Muniz, E. A., Murray, P. G., Musenich, R., Muusse, S., Nadji, S. L., Nagano, K., Nagano, S., Nagar, A., Nakamura, K., Nakano, H., Nakano, M., Nakashima, R., Nakayama, Y., Napolano, V, Nardecchia, I, Narikawa, T., Naticchioni, L., Nayak, B., Nayak, R. K., Negishi, R., Neil, B. F., Neilson, J., Nelemans, G., Nelson, T. J. N., Nery, M., Neubauer, P., Neunzert, A., K. Y., Ng, S. W. S., Ng, Nguyen, C., Nguyen, P., Nguyen, T., Quynh, L. Nguyen, W-T, Ni, Nichols, S. A., Nishizawa, A., Nissanke, S., Nitoglia, E., Nocera, F., Norman, M., North, C., Nozaki, S., Nuttall, L. K., Oberling, J., O'Brien, B. D., Obuchi, Y., O'Dell, J., Oelker, E., Ogaki, W., Oganesyan, G., J. J., Oh, Oh, K., S. H., Oh, Ohashi, M., Ohishi, N., Ohkawa, M., Ohme, F., Ohta, H., Okada, M. A., Okutani, Y., Okutomi, K., Olivetto, C., Oohara, K., Ooi, C., Oram, R., O'Reilly, B., Ormiston, R. G., Ormsby, N. D., Ortega, L. F., O'Shaughnessy, R., O'Shea, E., Oshino, S., Ossokine, S., Osthelder, C., Otabe, S., Ottaway, D. J., Overmier, H., Pace, A. E., Pagano, G., Page, M. A., Pagliaroli, G., Pai, A., Pai, S. A., Palamos, J. R., Palashov, O., Palomba, C., Pan, H., Pan, K., P, P. K., A, Pang, H., Pang, P. T. H., Pankow, C., Pannarale, F., Pant, B. C., Panther, F. H., Paoletti, F., Paoli, A., Paolone, A., Parisi, A., Park, H., Park, J., Parker, W., Pascucci, D., Pasqualetti, A., Passaquieti, R., Passuello, D., Patel, M., Pathak, M., Patricelli, B., Patron, A. S., Patrone, S., Paul, S., Payne, E., Pedraza, M., Pegoraro, M., Pele, A., Arellano, F. E. Pena, Penn, S., Perego, A., Pereira, A., Pereira, T., Perez, C. J., Perigois, C., Perkins, C. C., Perreca, A., Perries, S., Petermann, J., Petterson, D., Pfeiffer, H. P., Pham, K. A., Phukon, K. S., Piccinni, O. J., Pichot, M., Piendibene, M., Piergiovanni, F., Pierini, L., Pierro, V, Pillant, G., Pillas, M., Pilo, F., Pinard, L., Pinto, I. M., Pinto, M., Piotrzkowski, K., Pirello, M., Pitkin, M. D., Placidi, E., Planas, L., Plastino, W., Pluchar, C., Poggiani, R., Polini, E., Pong, D. Y. T., Ponrathnam, S., Popolizio, P., Porter, E. K., Poulton, R., Powell, J., Pracchia, M., Pradier, T., Prajapati, A. K., Prasai, K., Prasanna, R., Pratten, G., Principe, M., Prodi, G. A., Prokhorov, L., Prosposito, P., Prudenzi, L., Puecher, A., Punturo, M., Puosi, F., Puppo, P., Purrer, M., Qi, H., Quetschke, V, Quitzow-James, R., Raab, F. J., Raaijmakers, G., Radkins, H., Radulesco, N., Raffai, P., Rail, S. X., Raja, S., Rajan, C., Ramirez, K. E., Ramirez, T. D., Ramos-Buades, A., Rana, J., Rapagnani, P., Rapol, U. D., Ray, A., Raymond, V, Raza, N., Razzano, M., Read, J., Rees, L. A., Regimbau, T., Rei, L., Reid, S., Reid, S. W., Reitze, D. H., Relton, P., Renzini, A., Rettegno, P., Rezac, M., Ricci, F., Richards, D., Richardson, J. W., Richardson, L., Riemenschneider, G., Riles, K., Rinaldi, S., Rink, K., Rizzo, M., Robertson, N. A., Robie, R., Robinet, F., Rocchi, A., Rodriguez, S., Roll, Rollins, J. G., Romanelli, M., Romano, R., Romel, C. L., Romero-Rodriguez, A., Romero-Shaw, I. M., Romie, J. H., Ronchini, S., Rosa, L., Rose, C. A., Ross, M. P., Rowan, S., Rowlinson, S. J., Roy, S., Roy, Santosh, Roy, Soumen, Rozza, D., Ruggi, P., Ryan, K., Sachdev, S., Sadecki, T., Sadiq, J., Sago, N., Saito, S., Saito, Y., Sakai, K., Sakai, Y., Sakellariadou, M., Sakuno, Y., Salafia, O. S., Salconi, L., Saleem, M., Salemi, F., Samajdar, A., Sanchez, E. J., Sanchez, J. H., Sanchez, L. 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E., Zweizig, J., LIGO Sci Collaboration, Virgo, Collaboration, Kagra, Collaboration, Van Swinderen Institute for Particle Physics and G, Institut Lumière Matière [Villeurbanne] (ILM), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Astrophysique Relativiste Théories Expériences Métrologie Instrumentation Signaux (ARTEMIS), Université Nice Sophia Antipolis (1965 - 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D., Acernese, F., Ackley, K., Adams, C., Adhikari, N., Adhikari, R. X., Adya, V. B., Affeldt, C., Agarwal, D., Agathos, M., Agatsuma, K., Aggarwal, N., Aguiar, O. D., Aiello, L., Ain, A., Ajith, P., Akutsu, T., Albanesi, S., Allocca, A., Altin, P. A., Amato, A., Anand, C., Anand, S., Ananyeva, A., Anderson, S. B., Anderson, W. G., Ando, M., Andrade, T., Andres, N., Andric, T., Angelova, S. V., Ansoldi, S., Antelis, J. M., Antier, S., Appert, S., Arai, K., Arai, Y., Araki, S., Araya, A., Araya, M. C., Areeda, J. S., Arene, M., Aritomi, N., Arnaud, N., Aronson, S. M., Arun, K. G., Asada, H., Asali, Y., Ashton, G., Aso, Y., Assiduo, M., Aston, S. M., Astone, P., Aubin, F., Austin, C., Babak, S., Badaracco, F., Bader, M. K. M., Badger, C., Bae, S., Bae, Y., Baer, A. M., Bagnasco, S., Bai, Y., Baiotti, L., Baird, J., Bajpai, R., Ball, M., Ballardin, G., Ballmer, S. W., Balsamo, A., Baltus, G., Banagiri, S., Bankar, D., Barayoga, J. C., Barbieri, C., Barish, B. C., Barker, D., Barneo, P., Barone, F., Barr, B., Barsotti, L., Barsuglia, M., Barta, D., Bartlett, J., Barton, M. A., Bartos, I., Bassiri, R., Basti, A., Bawaj, M., Bayley, J. C., Baylor, A. C., Bazzan, M., Becsy, B., Bedakihale, V. M., Bejger, M., Belahcene, I., Benedetto, V., Beniwal, D., Bennett, T. F., Bentley, J. D., Benyaala, M., Bergamin, F., Berger, B. K., Bernuzzi, S., Bersanetti, D., Bertolini, A., Betzwieser, J., Beveridge, D., Bhandare, R., Bhardwaj, U., Bhattacharjee, D., Bhaumik, S., Bilenko, I. A., Billingsley, G., Bini, S., Birney, R., Birnholtz, O., Biscans, S., Bischi, M., Biscoveanu, S., Bisht, A., Biswas, B., Bitossi, M., Bizouard, M. -A., Blackburn, J. K., Blair, C. D., Blair, D. G., Blair, R. M., Bobba, F., Bode, N., Boer, M., Bogaert, G., Boldrini, M., Bonavena, L. D., Bondu, F., Bonilla, E., Bonnand, R., Booker, P., Boom, B. A., Bork, R., Boschi, V., Bose, N., Bose, S., Bossilkov, V., Boudart, V., Bouffanais, Y., Bozzi, A., Bradaschia, C., Brady, P. R., Bramley, A., Branch, A., Branchesi, M., Brau, J. E., Breschi, M., Briant, T., Briggs, J. H., Brillet, A., Brinkmann, M., Brockill, P., Brooks, A. F., Brooks, J., Brown, D. D., Brunett, S., Bruno, G., Bruntz, R., Bryant, J., Bulik, T., Bulten, H. J., Buonanno, A., Buscicchio, R., Buskulic, D., Buy, C., Byer, R. L., Cadonati, L., Cagnoli, G., Cahillane, C., Bustillo, J. C., Callaghan, J. D., Callister, T. A., Calloni, E., Cameron, J., Camp, J. B., Canepa, M., Canevarolo, S., Cannavacciuolo, M., Cannon, K. C., Cao, H., Cao, Z., Capocasa, E., Capote, E., Carapella, G., Carbognani, F., Carlin, J. B., Carney, M. F., Carpinelli, M., Carrillo, G., Carullo, G., Carver, T. L., Diaz, J. C., Casentini, C., Castaldi, G., Caudill, S., Cavaglia, M., Cavalier, F., Cavalieri, R., Ceasar, M., Cella, G., Cerda-Duran, P., Cesarini, E., Chaibi, W., Chakravarti, K., Subrahmanya, S. C., Champion, E., Chan, C. -H., Chan, C., Chan, C. L., Chan, K., Chan, M., Chandra, K., Chanial, P., Chao, S., Charlton, P., Chase, E. A., Chassande-Mottin, E., Chatterjee, C., Chatterjee, D., Chaturvedi, M., Chaty, S., Chen, C., Chen, H. Y., Chen, J., Chen, K., Chen, X., Chen, Y. -B., Chen, Y. -R., Chen, Z., Cheng, H., Cheong, C. K., Cheung, H. Y., Chia, H. Y., Chiadini, F., Chiang, C. -Y., Chiarini, G., Chierici, R., Chincarini, A., Chiofalo, M. L., Chiummo, A., Cho, G., Cho, H. S., Choudhary, R. K., Choudhary, S., Christensen, N., Chu, H., Chu, Q., Chu, Y. -K., Chua, S., Chung, K. W., Ciani, G., Ciecielag, P., Cieslar, M., Cifaldi, M., Ciobanu, A. A., Ciolfi, R., Cipriano, F., Cirone, A., Clara, F., Clark, E. N., Clark, J. A., Clarke, L., Clearwater, P., Clesse, S., Cleva, F., Coccia, E., Codazzo, E., Cohadon, P. -F., Cohen, D. E., Cohen, L., Colleoni, M., Collette, C. G., Colombo, A., Colpi, M., Compton, C. M., Constancio, M., Conti, L., Cooper, S. J., Corban, P., Corbitt, T. R., Cordero-Carrion, I., Corezzi, S., Corley, K. R., Cornish, N., Corre, D., Corsi, A., Cortese, S., Costa, C. A., Cotesta, R., Coughlin, M. W., Coulon, J. -P., Countryman, S. T., Cousins, B., Couvares, P., Coward, D. M., Cowart, M. J., Coyne, D. C., Coyne, R., Creighton, J. D. E., Creighton, T. D., Criswell, A. W., Croquette, M., Crowder, S. G., Cudell, J. R., Cullen, T. J., Cumming, A., Cummings, R., Cunningham, L., Cuoco, E., Curylo, M., Dabadie, P., Canton, T. D., Dall'Osso, S., Dalya, G., Dana, A., Daneshgaranbajastani, L. M., D'Angelo, B., Danilishin, S., D'Antonio, S., Danzmann, K., Darsow-Fromm, C., Dasgupta, A., Datrier, L. E. H., Datta, S., Dattilo, V., Dave, I., Davier, M., Davies, G. S., Davis, D., Davis, M. C., Daw, E. J., Dean, R., Debra, D., Deenadayalan, M., Degallaix, J., De Laurentis, M., Deleglise, S., Del Favero, V., De Lillo, F., De Lillo, N., Del Pozzo, W., Demarchi, L. M., De Matteis, F., D'Emilio, V., Demos, N., Dent, T., Depasse, A., De Pietri, R., De Rosa, R., De Rossi, C., Desalvo, R., De Simone, R., Dhurandhar, S., Diaz, M. C., Diaz-Ortiz, M., Didio, N. A., Dietrich, T., Di Fiore, L., Di Fronzo, C., Di Giorgio, C., Di Giovanni, F., Di Giovanni, M., Di Girolamo, T., Di Lieto, A., Ding, B., Di Pace, S., Di Palma, I., Di Renzo, F., Divakarla, A. K., Dmitriev, A., Doctor, Z., D'Onofrio, L., Donovan, F., Dooley, K. L., Doravari, S., Dorrington, I., Drago, M., Driggers, J. C., Drori, Y., Ducoin, J. -G., Dupej, P., Durante, O., D'Urso, D., Duverne, P. -A., Dwyer, S. E., Eassa, C., Easter, P. J., Ebersold, M., Eckhardt, T., Eddolls, G., Edelman, B., Edo, T. B., Edy, O., Effler, A., Eguchi, S., Eichholz, J., Eikenberry, S. S., Eisenmann, M., Eisenstein, R. A., Ejlli, A., Engelby, E., Enomoto, Y., Errico, L., Essick, R. C., Estelles, H., Estevez, D., Etienne, Z., Etzel, T., Evans, M., Evans, T. M., Ewing, B. E., Fafone, V., Fair, H., Fairhurst, S., Farah, A. M., Farinon, S., Farr, B., Farr, W. M., Farrow, N. W., Fauchon-Jones, E. J., Favaro, G., Favata, M., Fays, M., Fazio, M., Feicht, J., Fejer, M. M., Fenyvesi, E., Ferguson, D. L., Fernandez-Galiana, A., Ferrante, I., Ferreira, T. A., Fidecaro, F., Figura, P., Fiori, I., Fishbach, M., Fisher, R. P., Fittipaldi, R., Fiumara, V., Flaminio, R., Floden, E., Fong, H., Font, J. A., Fornal, B., Forsyth, P. W. F., Franke, A., Frasca, S., Frasconi, F., Frederick, C., Freed, J. P., Frei, Z., Freise, A., Frey, R., Fritschel, P., Frolov, V. V., Fronze, G. G., Fujii, Y., Fujikawa, Y., Fukunaga, M., Fukushima, M., Fulda, P., Fyffe, M., Gabbard, H. A., Gadre, B. U., Gair, J. R., Gais, J., Galaudage, S., Gamba, R., Ganapathy, D., Ganguly, A., Gao, D., Gaonkar, S. G., Garaventa, B., Garcia-Nunez, C., Garcia-Quiros, C., Garufi, F., Gateley, B., Gaudio, S., Gayathri, V., Ge, G. -G., Gemme, G., Gennai, A., George, J., Gerberding, O., Gergely, L., Gewecke, P., Ghonge, S., Ghosh, A., Ghosh, S., Giacomazzo, B., Giacoppo, L., Giaime, J. A., Giardina, K. D., Gibson, D. R., Gier, C., Giesler, M., Giri, P., Gissi, F., Glanzer, J., Gleckl, A. E., Godwin, P., Goetz, E., Goetz, R., Gohlke, N., Goncharov, B., Gonzalez, G., Gopakumar, A., Gosselin, M., Gouaty, R., Gould, D. W., Grace, B., Grado, A., Granata, M., Granata, V., Grant, A., Gras, S., Grassia, P., Gray, C., Gray, R., Greco, G., Green, A. C., Green, R., Gretarsson, A. M., Gretarsson, E. M., Griffith, D., Griffiths, W., Griggs, H. L., Grignani, G., Grimaldi, A., Grimm, S. J., Grote, H., Grunewald, S., Gruning, P., Guerra, D., Guidi, G. M., Guimaraes, A. R., Guixe, G., Gulati, H. K., Guo, H. -K., Guo, Y., Gupta, A., Gupta, P., Gustafson, E. 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J., Hoy, C. G., Hoyland, D., Hreibi, A., Hsieh, B. -H., Hsu, Y., Huang, G. -Z., Huang, H. -Y., Huang, P., Huang, Y. -C., Huang, Y. -J., Huang, Y., Hubner, M. T., Huddart, A. D., Hughey, B., Hui, D. C. Y., Hui, V., Husa, S., Huttner, S. H., Huxford, R., Huynh-Dinh, T., Ide, S., Idzkowski, B., Iess, A., Ikenoue, B., Imam, S., Inayoshi, K., Ingram, C., Inoue, Y., Ioka, K., Isi, M., Isleif, K., Ito, K., Itoh, Y., Iyer, B. R., Izumi, K., Jaberianhamedan, V., Jacqmin, T., Jadhav, S. J., Jadhav, S. P., James, A. L., Jan, A. Z., Jani, K., Janquart, J., Janssens, K., Janthalur, N. N., Jaranowski, P., Jariwala, D., Jaume, R., Jenkins, A. C., Jenner, K., Jeon, C., Jeunon, M., Jia, W., Jin, H. -B., Johns, G. R., Jones, A. W., Jones, D. I., Jones, J. D., Jones, P., Jones, R., Jonker, R. J. G., Ju, L., Jung, P., Jung, K., Junker, J., Juste, V., Kaihotsu, K., Kajita, T., Kakizaki, M., Kalaghatgi, C. V., Kalogera, V., Kamai, B., Kamiizumi, M., Kanda, N., Kandhasamy, S., Kang, G., Kanner, J. B., Kao, Y., Kapadia, S. J., Kapasi, D. P., Karat, S., Karathanasis, C., Karki, S., Kashyap, R., Kasprzack, M., Kastaun, W., Katsanevas, S., Katsavounidis, E., Katzman, W., Kaur, T., Kawabe, K., Kawaguchi, K., Kawai, N., Kawasaki, T., Kefelian, F., Keitel, D., Key, J. S., Khadka, S., Khalili, F. Y., Khan, S., Khazanov, E. A., Khetan, N., Khursheed, M., Kijbunchoo, N., Kim, C., Kim, J. C., Kim, J., Kim, K., Kim, W. S., Kim, Y. -M., Kimball, C., Kimura, N., Kinley-Hanlon, M., Kirchhoff, R., Kissel, J. S., Kita, N., Kitazawa, H., Kleybolte, L., Klimenko, S., Knee, A. M., Knowles, T. D., Knyazev, E., Koch, P., Koekoek, G., Kojima, Y., Kokeyama, K., Koley, S., Kolitsidou, P., Kolstein, M., Komori, K., Kondrashov, V., Kong, A. K. H., Kontos, A., Koper, N., Korobko, M., Kotake, K., Kovalam, M., Kozak, D. B., Kozakai, C., Kozu, R., Kringel, V., Krishnendu, N. V., Krolak, A., Kuehn, G., Kuei, F., Kuijer, P., Kumar, A., Kumar, P., Kumar, R., Kume, J., Kuns, K., Kuo, C., Kuo, H. -S., Kuromiya, Y., Kuroyanagi, S., Kusayanagi, K., Kuwahara, S., Kwak, K., Lagabbe, P., Laghi, D., Lalande, E., Lam, T. L., Lamberts, A., Landry, M., Lane, B. B., Lang, R. N., Lange, J., Lantz, B., La Rosa, I., Lartaux-Vollard, A., Lasky, P. D., Laxen, M., Lazzarini, A., Lazzaro, C., Leaci, P., Leavey, S., Lecoeuche, Y. K., Lee, H. K., Lee, H. M., Lee, H. W., Lee, J., Lee, K., Lee, R., Lehmann, J., Lemaitre, A., Leonardi, M., Leroy, N., Letendre, N., Levesque, C., Levin, Y., Leviton, J. N., Leyde, K., Li, A. K. Y., Li, B., Li, J., Li, K. L., Li, T. G. F., Li, X., Lin, C. -Y., Lin, F. -K., Lin, F. -L., Lin, H. L., Lin, L. C. -C., Linde, F., Linker, S. D., Linley, J. N., Littenberg, T. B., Liu, G. C., Liu, J., Liu, K., Liu, X., Llamas, F., Llorens-Monteagudo, M., Lo, R. K. L., Lockwood, A., London, L. T., Longo, A., Lopez, D., Portilla, M. L., Lorenzini, M., Loriette, V., Lormand, M., Losurdo, G., Lott, T. P., Lough, J. D., Lousto, C. O., Lovelace, G., Lucaccioni, J. F., Luck, H., Lumaca, D., Lundgren, A. P., Luo, L. -W., Lynam, J. E., Macas, R., Macinnis, M., Macleod, D. M., Macmillan, I. A. O., Macquet, A., Hernandez, I. M., Magazzu, C., Magee, R. M., Maggiore, R., Magnozzi, M., Mahesh, S., Majorana, E., Makarem, C., Maksimovic, I., Maliakal, S., Malik, A., Man, N., Mandic, V., Mangano, V., Mango, J. L., Mansell, G. L., Manske, M., Mantovani, M., Mapelli, M., Marchesoni, F., Marchio, M., Marion, F., Mark, Z., Marka, S., Marka, Z., Markakis, C., Markosyan, A. S., Markowitz, A., Maros, E., Marquina, A., Marsat, S., Martelli, F., Martin, I. W., Martin, R. M., Martinez, M., Martinez, V. A., Martinez, V., Martinovic, K., Martynov, D. V., Marx, E. J., Masalehdan, H., Mason, K., Massera, E., Masserot, A., Massinger, T. J., Masso-Reid, M., Mastrogiovanni, S., Matas, A., Mateu-Lucena, M., Matichard, F., Matiushechkina, M., Mavalvala, N., Mccann, J. J., Mccarthy, R., Mcclelland, D. E., Mcclincy, P. K., Mccormick, S., Mcculler, L., Mcghee, G. I., Mcguire, S. C., Mcisaac, C., Mciver, J., Mcrae, T., Mcwilliams, S. T., Meacher, D., Mehmet, M., Mehta, A. K., Meijer, Q., Melatos, A., Melchor, D. A., Mendell, G., Menendez-Vazquez, A., Menoni, C. S., Mercer, R. A., Mereni, L., Merfeld, K., Merilh, E. L., Merritt, J. D., Merzougui, M., Meshkov, S., Messenger, C., Messick, C., Meyers, P. M., Meylahn, F., Mhaske, A., Miani, A., Miao, H., Michaloliakos, I., Michel, C., Michimura, Y., Middleton, H., Milano, L., Miller, A. L., Miller, A., Miller, B., Millhouse, M., Mills, J. C., Milotti, E., Minazzoli, O., Minenkov, Y., Mio, N., Mir, L. M., Miravet-Tenes, M., Mishra, C., Mishra, T., Mistry, T., Mitra, S., Mitrofanov, V. P., Mitselmakher, G., Mittleman, R., Miyakawa, O., Miyamoto, A., Miyazaki, Y., Miyo, K., Miyoki, S., Mo, G., Moguel, E., Mogushi, K., Mohapatra, S. R. P., Mohite, S. R., Molina, I., Molina-Ruiz, M., Mondin, M., Montani, M., Moore, C. J., Moraru, D., Morawski, F., More, A., Moreno, C., Moreno, G., Mori, Y., Morisaki, S., Moriwaki, Y., Mours, B., Mow-Lowry, C. M., Mozzon, S., Muciaccia, F., Mukherjee, A., Mukherjee, D., Mukherjee, S., Mukund, N., Mullavey, A., Munch, J., Muniz, E. A., Murray, P. G., Musenich, R., Muusse, S., Nadji, S. L., Nagano, K., Nagano, S., Nagar, A., Nakamura, K., Nakano, H., Nakano, M., Nakashima, R., Nakayama, Y., Napolano, V., Nardecchia, I., Narikawa, T., Naticchioni, L., Nayak, B., Nayak, R. K., Negishi, R., Neil, B. F., Neilson, J., Nelemans, G., Nelson, T. J. N., Nery, M., Neubauer, P., Neunzert, A., Ng, K. Y., Ng, S. W. S., Nguyen, C., Nguyen, P., Nguyen, T., Quynh, L. N., Ni, W. -T., Nichols, S. A., Nishizawa, A., Nissanke, S., Nitoglia, E., Nocera, F., Norman, M., North, C., Nozaki, S., Nuttall, L. K., Oberling, J., O'Brien, B. D., Obuchi, Y., O'Dell, J., Oelker, E., Ogaki, W., Oganesyan, G., Oh, J. J., Oh, K., Oh, S. H., Ohashi, M., Ohishi, N., Ohkawa, M., Ohme, F., Ohta, H., Okada, M. A., Okutani, Y., Okutomi, K., Olivetto, C., Oohara, K., Ooi, C., Oram, R., O'Reilly, B., Ormiston, R. G., Ormsby, N. D., Ortega, L. F., O'Shaughnessy, R., O'Shea, E., Oshino, S., Ossokine, S., Osthelder, C., Otabe, S., Ottaway, D. J., Overmier, H., Pace, A. E., Pagano, G., Page, M. A., Pagliaroli, G., Pai, A., Pai, S. A., Palamos, J. R., Palashov, O., Palomba, C., Pan, H., Pan, K., Panda, P. K., Pang, H., Pang, P. T. H., Pankow, C., Pannarale, F., Pant, B. C., Panther, F. H., Paoletti, F., Paoli, A., Paolone, A., Parisi, A., Park, H., Park, J., Parker, W., Pascucci, D., Pasqualetti, A., Passaquieti, R., Passuello, D., Patel, M., Pathak, M., Patricelli, B., Patron, A. S., Patrone, S., Paul, S., Payne, E., Pedraza, M., Pegoraro, M., Pele, A., Arellano, F. E. P., Penn, S., Perego, A., Pereira, A., Pereira, T., Perez, C. J., Perigois, C., Perkins, C. C., Perreca, A., Perries, S., Petermann, J., Petterson, D., Pfeiffer, H. P., Pham, K. A., Phukon, K. S., Piccinni, O. J., Pichot, M., Piendibene, M., Piergiovanni, F., Pierini, L., Pierro, V., Pillant, G., Pillas, M., Pilo, F., Pinard, L., Pinto, I., Pinto, M., Piotrzkowski, K., Pirello, M., Pitkin, M. D., Placidi, E., Planas, L., Plastino, W., Pluchar, C., Poggiani, R., Polini, E., Pong, D. Y. T., Ponrathnam, S., Popolizio, P., Porter, E. K., Poulton, R., Powell, J., Pracchia, M., Pradier, T., Prajapati, A. K., Prasai, K., Prasanna, R., Pratten, G., Principe, M., Prodi, G. A., Prokhorov, L., Prosposito, P., Prudenzi, L., Puecher, A., Punturo, M., Puosi, F., Puppo, P., Purrer, M., Qi, H., Quetschke, V., Quitzow-James, R., Raab, F. J., Raaijmakers, G., Radkins, H., Radulesco, N., Raffai, P., Rail, S. X., Raja, S., Rajan, C., Ramirez, K. E., Ramirez, T. D., Ramos-Buades, A., Rana, J., Rapagnani, P., Rapol, U. D., Ray, A., Raymond, V., Raza, N., Razzano, M., Read, J., Rees, L. A., Regimbau, T., Rei, L., Reid, S., Reid, S. W., Reitze, D. H., Relton, P., Renzini, A., Rettegno, P., Rezac, M., Ricci, F., Richards, D., Richardson, J. W., Richardson, L., Riemenschneider, G., Riles, K., Rinaldi, S., Rink, K., Rizzo, M., Robertson, N. A., Robie, R., Robinet, F., Rocchi, A., Rodriguez, S., Rolland, L., Rollins, J. G., Romanelli, M., Romano, R., Romel, C. L., Romero-Rodriguez, A., Romero-Shaw, I. M., Romie, J. H., Ronchini, S., Rosa, L., Rose, C. A., Rosinska, D., Ross, M. P., Rowan, S., Rowlinson, S. J., Roy, S., Rozza, D., Ruggi, P., Ryan, K., Sachdev, S., Sadecki, T., Sadiq, J., Sago, N., Saito, S., Saito, Y., Sakai, K., Sakai, Y., Sakellariadou, M., Sakuno, Y., Salafia, O. S., Salconi, L., Saleem, M., Salemi, F., Samajdar, A., Sanchez, E. J., Sanchez, J. H., Sanchez, L. E., Sanchis-Gual, N., Sanders, J. R., Sanuy, A., Saravanan, T. R., Sarin, N., Sassolas, B., Satari, H., Sathyaprakash, B. S., Sato, S., Sato, T., Sauter, O., Savage, R. L., Sawada, T., Sawant, D., Sawant, H. L., Sayah, S., Schaetzl, D., Scheel, M., Scheuer, J., Schiworski, M., Schmidt, P., Schmidt, S., Schnabel, R., Schneewind, M., Schofield, R. M. S., Schonbeck, A., Schulte, B. W., Schutz, B. F., Schwartz, E., Scott, J., Scott, S. M., Seglar-Arroyo, M., Sekiguchi, T., Sekiguchi, Y., Sellers, D., Sengupta, A. S., Sentenac, D., Seo, E. G., Sequino, V., Sergeev, A., Setyawati, Y., Shaffer, T., Shahriar, M. S., Shams, B., Shao, L., Sharma, A., Sharma, P., Shawhan, P., Shcheblanov, N. S., Shibagaki, S., Shikauchi, M., Shimizu, R., Shimoda, T., Shimode, K., Shinkai, H., Shishido, T., Shoda, A., Shoemaker, D. H., Shoemaker, D. M., Shyamsundar, S., Sieniawska, M., Sigg, D., Singer, L. P., Singh, D., Singh, N., Singha, A., Sintes, A. M., Sipala, V., Skliris, V., Slagmolen, B. J. J., Slaven-Blair, T. J., Smetana, J., Smith, J. R., Smith, R. J. E., Soldateschi, J., Somala, S. N., Somiya, K., Son, E. J., Soni, K., Soni, S., Sordini, V., Sorrentino, F., Sorrentino, N., Sotani, H., Soulard, R., Souradeep, T., Sowell, E., Spagnuolo, V., Spencer, A. P., Spera, M., Srinivasan, R., Srivastava, A. K., Srivastava, V., Staats, K., Stachie, C., Steer, D. A., Steinlechner, J., Steinlechner, S., Stops, D. J., Stover, M., Strain, K. A., Strang, L. C., Stratta, G., Strunk, A., Sturani, R., Stuver, A. L., Sudhagar, S., Sudhir, V., Sugimoto, R., Suh, H. G., Summerscales, T. Z., Sun, H., Sun, L., Sunil, S., Sur, A., Suresh, J., Sutton, P. J., Suzuki, T., Swinkels, B. L., Szczepanczyk, M. J., Szewczyk, P., Tacca, M., Tagoshi, H., Tait, S. C., Takahashi, H., Takahashi, R., Takamori, A., Takano, S., Takeda, H., Takeda, M., Talbot, C. J., Talbot, C., Tanaka, H., Tanaka, K., Tanaka, T., Tanasijczuk, A. J., Tanioka, S., Tanner, D. B., Tao, D., Tao, L., Martin, E. N. T. S., Taranto, C., Tasson, J. D., Telada, S., Tenorio, R., Terhune, J. E., Terkowski, L., Thirugnanasambandam, M. P., Thomas, M., Thomas, P., Thompson, J. E., Thondapu, S. R., Thorne, K. A., Thrane, E., Tiwari, S., Tiwari, V., Toivonen, A. M., Toland, K., Tolley, A. E., Tomaru, T., Tomigami, Y., Tomura, T., Tonelli, M., Torres-Forne, A., Torrie, C. I., E Melo, I. T., Toyra, D., Trapananti, A., Travasso, F., Traylor, G., Trevor, M., Tringali, M. C., Tripathee, A., Troiano, L., Trovato, A., Trozzo, L., Trudeau, R. J., Tsai, D. S., Tsai, D., Tsang, K. W., Tsang, T., Tsao, J. -S., Tse, M., Tso, R., Tsubono, K., Tsuchida, S., Tsukada, L., Tsuna, D., Tsutsui, T., Tsuzuki, T., Turbang, K., Turconi, M., Tuyenbayev, D., Ubhi, A. S., Uchikata, N., Uchiyama, T., Udall, R. P., Ueda, A., Uehara, T., Ueno, K., Ueshima, G., Uraguchi, F., Urban, A. L., Ushiba, T., Utina, A., Vahlbruch, H., Vajente, G., Vajpeyi, A., Valdes, G., Valentini, M., Valsan, V., Van Bakel, N., Van Beuzekom, M., Van Den Brand, J. F. J., Van Den Broeck, C., Vander-Hyde, D. C., Van Der Schaaf, L., Van Heijningen, J. V., Vanosky, J., Van Putten, M. H. P. M., Van Remortel, N., Vardaro, M., Vargas, A. F., Varma, V., Vasuth, M., Vecchio, A., Vedovato, G., Veitch, J., Veitch, P. J., Venneberg, J., Venugopalan, G., Verkindt, D., Verma, P., Verma, Y., Veske, D., Vetrano, F., Vicere, A., Vidyant, S., Viets, A. D., Vijaykumar, A., Villa-Ortega, V., Vinet, J. -Y., Virtuoso, A., Vitale, S., Vo, T., Vocca, H., Von Reis, E. R. G., Von Wrangel, J. S. A., Vorvick, C., Vyatchanin, S. P., Wade, L. E., Wade, M., Wagner, K. J., Walet, R. C., Walker, M., Wallace, G. S., Wallace, L., Walsh, S., Wang, J., Wang, J. Z., Wang, W. H., Ward, R. L., Warner, J., Was, M., Washimi, T., Washington, N. Y., Watchi, J., Weaver, B., Webster, S. A., Weinert, M., Weinstein, A. J., Weiss, R., Weller, C. M., Wellmann, F., Wen, L., Wessels, P., Wette, K., Whelan, J. T., White, D. D., Whiting, B. F., Whittle, C., Wilken, D., Williams, D., Williams, M. J., Williamson, A. R., Willis, J. L., Willke, B., Wilson, D. J., Winkler, W., Wipf, C. C., Wlodarczyk, T., Woan, G., Woehler, J., Wofford, J. K., Wong, I. C. F., Wu, C., Wu, D. S., Wu, H., Wu, S., Wysocki, D. M., Xiao, L., Xu, W. -R., Yamada, T., Yamamoto, H., Yamamoto, K., Yamamoto, T., Yamashita, K., Yamazaki, R., Yang, F. W., Yang, L., Yang, Y., Yang, Z., Yap, M. J., Yeeles, D. W., Yelikar, A. B., Ying, M., Yokogawa, K., Yokoyama, J., Yokozawa, T., Yoo, J., Yoshioka, T., Yu, H., Yuzurihara, H., Zadrozny, A., Zanolin, M., Zeidler, S., Zelenova, T., Zendri, J. -P., Zevin, M., Zhan, M., Zhang, H., Zhang, J., Zhang, L., Zhang, T., Zhang, Y., Zhao, C., Zhao, G., Zhao, Y., Zhou, R., Zhou, Z., Zhu, X. J., Zhu, Z. -H., Zucker, M. E., Zweizig, J., Andrić, T., Arai, Koji, Arai, Koya, Arène, M., Bécsy, B., Bustillo, J. Calderón, Diaz, J. Casanueva, Cavaglià, M., Cerdá-Durán, P., Subrahmanya, S. Chalathadka, Chatterjee, Debarati, Chatterjee, Deep, Chiang, C-Y., Chu, Y-K., Cieślar, M., Cordero-Carrión, I., Curyło, M., Canton, T. Dal, Dall’Osso, S., Dálya, G., D’Angelo, B., D’Antonio, S., Deléglise, S., D’Emilio, V., Díaz, M. C., D’Onofrio, L., D’Urso, D., Estellés, H., Fronzé, G. G., García-Núñez, C., García-Quirós, C., Ghosh, Abhirup, Ghosh, Archisman, Ghosh, Shaon, Ghosh, Shrobana, González, G., Guixé, G., Gupta, Anchal, Gupta, Anuradha, Vivanco, F. Hernandez, Hsieh, B-H., Huang, G-Z., Huang, H-Y., Huang, Y-C., Hübner, M. T., Kéfélian, F., Królak, A., Kumar, Rahul, Kumar, Rakesh, Kuo, H-S., Lemaître, A., Lin, C-Y., Lin, F-K., Lin, F-L., Portilla, M. Lopez, Lück, H., Hernandez, I. Magaña, Magazzù, C., Márka, S., Márka, Z., Mir, Ll. M., Miravet-Tenés, M., Mo, Geoffrey, Mukherjee, Arunava, Mukherjee, Soma, Mukherjee, Subroto, Mukherjee, Suvodip, Muñiz, E. A., Quynh, L. Nguyen, O’Brien, B. D., O’Dell, J., O’Reilly, B., O’Shaughnessy, R., O’Shea, E., Arellano, F. E. Peña, Périgois, C., Perriès, S., Pinto, I. M., Pürrer, M., Romero-Rodríguez, A., Rosińska, D., Roy, Santosh, Roy, Soumen, Schönbeck, A., Suzuki, Takamasa, Suzuki, Toshikazu, Szczepańczyk, M. J., Tanaka, Kazuyuki, Tanaka, Kenta, Tanaka, Taiki, Tanaka, Takahiro, Martin, E. N. Tapia San, Martín, E. N. Tapia San, Tiwari, Shubhanshu, Tiwari, Srishti, Torres-Forné, A., e Melo, I. Tosta, Töyrä, D., Tsao, J-S., van Bakel, N., van Beuzekom, M., van den Brand, J. F. J., van der Schaaf, L., van Heijningen, J. V., van Putten, M. H. P. M., van Remortel, N., Vasúth, M., Viceré, A., von Reis, E. R. G., von Wrangel, J. S. A., Weßels, P., Xu, W-R., Yamamoto, Kazuhiro, Yamamoto, Kohei, Yang, Yang, Yu, Hang, Yu, Haocun, Zadrożny, A., Zhao, Yue, Other Research IHEF (IoP, FNWI), High Energy Astrophys. & Astropart. Phys (API, FNWI), Astroparticle Physics (IHEF, IoP, FNWI), Gravitation and Astroparticle Physics Amsterdam, IoP (FNWI), The LIGO Scientific Collaboration, The Virgo Collaboration, The KAGRA Collaboration, Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-École Nationale Supérieure des Sciences Appliquées et de Technologie (ENSSAT)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), RS: FSE Grav. waves and fundamental physics, Grav. waves and fundamental physics, RS: FSE MSP, Abbott, R, Abbott, Td, Acernese, F, Ackley, K, Adams, C, Adhikari, N, Adhikari, Rx, Adya, Vb, Affeldt, C, Agarwal, D, Agathos, M, Agatsuma, K, Aggarwal, N, Aguiar, Od, Aiello, L, Ain, A, Ajith, P, Akutsu, T, Albanesi, S, Allocca, A, Altin, Pa, Amato, A, Anand, C, Anand, S, Ananyeva, A, Anderson, Sb, Anderson, Wg, Ando, M, Andrade, T, Andres, N, Angelova, Sv, Ansoldi, S, Antelis, Jm, Antier, S, Appert, S, Arai, K, Arai, Y, Araki, S, Araya, A, Araya, Mc, Areeda, J, Arene, M, Aritomi, N, Arnaud, N, Aronson, Sm, Arun, Kg, Asada, H, Asali, Y, Ashton, G, Aso, Y, Assiduo, M, Aston, Sm, Astone, P, Aubin, F, Austin, C, Babak, S, Badaracco, F, Bader, Mkm, Badger, C, Bae, S, Bae, Y, Baer, Am, Bagnasco, S, Bai, Y, Baiotti, L, Baird, J, Bajpai, R, Ball, M, Ballardin, G, Ballmer, Sw, Balsamo, A, Baltus, G, Banagiri, S, Bankar, D, Barayoga, Jc, Barbieri, C, Barish, Bc, Barker, D, Barneo, P, Barone, F, Barr, B, Barsotti, L, Barsuglia, M, Barta, D, Bartlett, J, Barton, Ma, Bartos, I, Bassiri, R, Basti, A, Bawaj, M, Bayley, Jc, Baylor, Ac, Bazzan, M, Becsy, B, Bedakihale, Vm, Bejger, M, Belahcene, I, Benedetto, V, Beniwal, D, Bennett, Tf, Bentley, Jd, Benyaala, M, Bergamin, F, Berger, Bk, Bernuzzi, S, Bersanetti, D, Bertolini, A, Betzwieser, J, Beveridge, D, Bhandare, R, Bhardwaj, U, Bhattacharjee, D, Bhaumik, S, Bilenko, Ia, Billingsley, G, Bini, S, Birney, R, Birnholtz, O, Biscans, S, Bischi, M, Biscoveanu, S, Bisht, A, Biswas, B, Bitossi, M, Bizouard, Ma, Blackburn, Jk, Blair, Cd, Blair, Dg, Blair, Rm, Bobba, F, Bode, N, Boer, M, Bogaert, G, Boldrini, M, Bonavena, Ld, Bondu, F, Bonilla, E, Bonnand, R, Booker, P, Boom, Ba, Bork, R, Boschi, V, Bose, N, Bose, S, Bossilkov, V, Boudart, V, Bouffanais, Y, Bozzi, A, Bradaschia, C, Brady, Pr, Bramley, A, Branch, A, Branchesi, M, Brau, Je, Breschi, M, Briant, T, Briggs, Jh, Brillet, A, Brinkmann, M, Brockill, P, Brooks, Af, Brooks, J, Brown, Dd, Brunett, S, Bruno, G, Bruntz, R, Bryant, J, Bulik, T, Bulten, Hj, Buonanno, A, Buscicchio, R, Buskulic, D, Buy, C, Byer, Rl, Cadonati, L, Cagnoli, G, Cahillane, C, Bustillo, Jc, Callaghan, Jd, Callister, Ta, Calloni, E, Cameron, J, Camp, Jb, Canepa, M, Canevarolo, S, Cannavacciuolo, M, Cannon, Kc, Cao, H, Cao, Z, Capocasa, E, Capote, E, Carapella, G, Carbognani, F, Carlin, Jb, Carney, Mf, Carpinelli, M, Carrillo, G, Carullo, G, Carver, Tl, Diaz, Jc, Casentini, C, Castaldi, G, Caudill, S, Cavaglia, M, Cavalier, F, Cavalieri, R, Ceasar, M, Cella, G, Cerda-Duran, P, Cesarini, E, Chaibi, W, Chakravarti, K, Subrahmanya, Sc, Champion, E, Chan, Ch, Chan, C, Chan, Cl, Chan, K, Chan, M, Chandra, K, Chanial, P, Chao, S, Charlton, P, Chase, Ea, Chassande-Mottin, E, Chatterjee, C, Chatterjee, D, Chaturvedi, M, Chaty, S, Chen, C, Chen, Hy, Chen, J, Chen, K, Chen, X, Chen, Yb, Chen, Yr, Chen, Z, Cheng, H, Cheong, Ck, Cheung, Hy, Chia, Hy, Chiadini, F, Chiang, Cy, Chiarini, G, Chierici, R, Chincarini, A, Chiofalo, Ml, Chiummo, A, Cho, G, Cho, H, Choudhary, Rk, Choudhary, S, Christensen, N, Chu, H, Chu, Q, Chu, Yk, Chua, S, Chung, Kw, Ciani, G, Ciecielag, P, Cifaldi, M, Ciobanu, Aa, Ciolfi, R, Cipriano, F, Cirone, A, Clara, F, Clark, En, Clark, Ja, Clarke, L, Clearwater, P, Clesse, S, Cleva, F, Coccia, E, Codazzo, E, Cohadon, Pf, Cohen, De, Cohen, L, Colleoni, M, Collette, Cg, Colombo, A, Colpi, M, Compton, Cm, Constancio, M, Conti, L, Cooper, Sj, Corban, P, Corbitt, Tr, Cordero-Carrion, I, Corezzi, S, Corley, Kr, Cornish, N, Corre, D, Corsi, A, Cortese, S, Costa, Ca, Cotesta, R, Coughlin, Mw, Coulon, Jp, Countryman, St, Cousins, B, Couvares, P, Coward, Dm, Cowart, Mj, Coyne, Dc, Coyne, R, Creighton, Jde, Creighton, Td, Criswell, Aw, Croquette, M, Crowder, Sg, Cudell, Jr, Cullen, Tj, Cumming, A, Cummings, R, Cunningham, L, Cuoco, E, Dabadie, P, Dal Canton, T, Dall'Osso, S, Dalya, G, Dana, A, Daneshgaranbajastani, Lm, D'Angelo, B, Danilishin, S, D'Antonio, S, Danzmann, K, Darsow-Fromm, C, Dasgupta, A, Datrier, Leh, Datta, S, Dattilo, V, Dave, I, Davier, M, Davies, G, Davis, D, Davis, Mc, Daw, Ej, Dean, R, Debra, D, Deenadayalan, M, Degallaix, J, De Laurentis, M, Deleglise, S, Del Favero, V, De Lillo, F, De Lillo, N, Del Pozzo, W, Demarchi, Lm, De Matteis, F, D'Emilio, V, Demos, N, Dent, T, Depasse, 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A, Van Bakel, N, Van Beuzekom, M, Van Den Brand, J, Van Den Broeck, C, Vander-Hyde, D, Van Der Schaaf, L, Van Heijningen, J, Van Putten, M, Van Remortel, N, Vargas, A, Veitch, P, Viets, A, Vinet, J, Von Reis, E, Von Wrangel, J, Vyatchanin, S, Wade, L, Wagner, K, Walet, R, Wang, W, Ward, R, Washington, N, Webster, S, Weinstein, A, Weller, C, Whelan, J, White, D, Whiting, B, Williams, M, Williamson, A, Willis, J, Wilson, D, Wipf, C, Wofford, J, Wong, I, Wysocki, D, Xu, W, Yang, F, Yap, M, Yeeles, D, Yelikar, A, Zadrozny, A, Zendri, J, Zhu, X, Zhu, Z, Zucker, M, (Astro)-Particles Physics, LIGO Sci Collaboration, Virgo Collaboration, and KAGRA Collaboration
Subjects: coupling: (dark matter baryon), Nuclear and High Energy Physics, data analysis method, Cosmology and Nongalactic Astrophysics (astro-ph.CO), gr-qc, Astronomy, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, detector: noise, General Relativity and Quantum Cosmology (gr-qc), Astrophysics::Cosmology and Extragalactic Astrophysics, Astronomy & Astrophysics, dark matter: direct detection, coupling: minimal, General Relativity and Quantum Cosmology, dark matter, Physics, Particles & Fields, gravitational wave detectors, High Energy Physics - Phenomenology (hep-ph), Fourier transformation, correlation function, LIGO, gravitational wave, QC, QB, Settore FIS/01, Science & Technology, mirror: oscillation, Physics, gravitational radiation, tachyon: stability, hep-ph, field theory: scalar, detector: sensitivity, High Energy Physics - Phenomenology, cosmic string: decay, VIRGO, Physics and Astronomy, [PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph], Physical Sciences, astro-ph.CO, [PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc], gravitational radiation detector: interferometer, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: LIGO Scientific Collaboration - Virgo Collaboration - KAGRA Collaboration: Abbott, R. et al., We present a search for dark photon dark matter that could couple to gravitational-wave interferometers using data from Advanced LIGO and Virgo’s third observing run. To perform this analysis, we use two methods, one based on cross-correlation of the strain channels in the two nearly aligned LIGO detectors, and one that looks for excess power in the strain channels of the LIGO and Virgo detectors. The excess power method optimizes the Fourier transform coherence time as a function of frequency, to account for the expected signal width due to Doppler modulations. We do not find any evidence of dark photon dark matter with a mass between mA∼10−14–10−11 eV/c2, which corresponds to frequencies between 10–2000 Hz, and therefore provide upper limits on the square of the minimum coupling of dark photons to baryons, i.e., U(1)B dark matter. For the cross-correlation method, the best median constraint on the squared coupling is ∼1.31×10−47 at mA∼4.2×10−13eV/c2; for the other analysis, the best constraint is ∼2.4×10−47 at mA∼5.7×10−13eV/c2. These limits improve upon those obtained in direct dark matter detection experiments by a factor of ∼100 for mA∼[2–4]×10−13eV/c2, and are, in absolute terms, the most stringent constraint so far in a large mass range mA∼2×10−13–8×10−12eV/c2., This material is based upon work supported by NSF’s LIGO Laboratory which is a major facility fully funded by the National Science Foundation. The authors also gratefully acknowledge the support of the Science and Technology Facilities Council (STFC) of the United Kingdom, the Max-Planck-Society (MPS), and the State of Niedersachsen/ Germany for support of the construction of Advanced LIGO and construction and operation of the GEO600 detector. Additional support for Advanced LIGO was provided by the Australian Research Council. The authors gratefully acknowledge the Italian Istituto Nazionale di Fisica Nucleare (INFN), the French Centre National de la Recherche Scientifique (CNRS) and the Netherlands Organization for Scientific Research, for the construction and operation of the Virgo detector and the creation and support of the EGO consortium. The authors also gratefully acknowledge research support fromthese agencies as well as by the Council of Scientific and Industrial Research of India, the Department of Science and Technology, India, the Science & Engineering Research Board (SERB), India, the Ministry of Human Resource Development, India, the Spanish Agencia Estatal de Investigación, the Vicepresidencia i Conselleria d’Innovació, Recerca i Turisme and the Conselleria d’Educació i Universitat del Govern de les Illes Balears, the Conselleria d’Innovació, Universitats, Ciencia i Societat Digital de la Generalitat Valenciana and the CERCA Programme Generalitat de Catalunya, Spain, the National Science Centre of Poland and the Foundation for Polish Science (FNP), the Swiss National Science Foundation (SNSF), the Russian Foundation for Basic Research, the Russian Science Foundation, the European Commission, the European Regional Development Funds (ERDF), the Royal Society, the Scottish Funding Council, the Scottish Universities Physics Alliance, the Hungarian Scientific Research Fund (OTKA), the French Lyon Institute of Origins (LIO), the Belgian Fonds de la Recherche Scientifique (FRS-FNRS), Actions de Recherche Concert´ees (ARC) and Fonds Wetenschappelijk Onderzoek—Vlaanderen (FWO), Belgium, the Paris Île-de-France Region, the National Research, Development and Innovation Office Hungary (NKFIH), the National Research Foundation of Korea, the Natural Science and Engineering Research Council Canada, Canadian Foundation for Innovation (CFI), the Brazilian Ministry of Science, Technology, and Innovations, the International Center for Theoretical Physics South American Institute for Fundamental Research (ICTPSAIFR), the Research Grants Council of Hong Kong, the National Natural Science Foundation of China (NSFC), the Leverhulme Trust, the Research Corporation, the Ministry of Science and Technology (MOST), Taiwan, the United States Department of Energy, and the Kavli Foundation. The authors gratefully acknowledge the support of the NSF, STFC, INFN and CNRS for provision of computational resources. This work was supported by MEXT, JSPS Leading-edge Research Infrastructure Program, JSPS Grant-in-Aid for Specially Promoted Research 26000005, JSPS Grant-in-Aid for Scientific Research on Innovative Areas 2905: No. JP17H06358, No. JP17H06361 and No. JP17H06364, JSPS Core-to-Core Program A. Advanced Research Networks, JSPS Grant-in-Aid for Scientific Research (S) No. 17H06133, the joint research program of the Institute forCosmic Ray Research, University of Tokyo, National Research Foundation (NRF) and Computing Infrastructure Project of KISTI-GSDC in Korea, Academia Sinica (AS), AS Grid Center (ASGC) and the Ministry of Science and Technology (MoST) in Taiwan under grants including AS-CDA-105-M06, Advanced Technology Center (ATC) of NAOJ, and Mechanical Engineering Center of KEK.
Published: 2022
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39. All-sky search for gravitational wave emission from scalar boson clouds around spinning black holes in LIGO O3 data

Author: Abbott, R., Abe, H., Acernese, F., Ackley, K., Adhikari, N., Adhikari, R. X., Adkins, V. K., Adya, V. B., Affeldt, C., Agarwal, D., Agathos, M., Agatsuma, K., Aggarwal, N., Aguiar, O. D., Aiello, L., Ain, A., Ajith, P., Akutsu, T., Albanesi, S., Alfaidi, R. A., Allocca, A., Altin, P. A., Amato, A., Ananyeva, A., Anderson, S. B., Anderson, W. G., Ando, M., Andrade, T., Andres, N., Andres-Carcasona, M., Angelova, V, Ansoldi, S., Antelis, J. M., Antier, S., Apostolatos, T., Appavuravther, E. Z., Appert, S., Apple, S. K., Arai, K., Araya, A., Araya, M. C., Areeda, J. S., Arene, M., Aritomi, N., Arnaud, N., Arogeti, M., Aronson, S. M., Arun, K. G., Asada, H., Asali, Y., Ashton, G., Aso, Y., Assiduo, M., Melo, S. Assis de Souza, Aston, S. M., Astone, P., Aubin, F., Aultoneal, K., Austin, C., Babak, S., Badaracco, F., Bader, M. K. M., Badger, C., Bae, S., Bae, Y., Baer, A. M., Bagnasco, S., Bai, Y., Baird, J., Bajpai, R., Baka, T., Ball, M., Ballardin, G., Ballmer, S. W., Balsamo, A., Baltus, G., Banagiri, S., Banerjee, B., Bankar, D., Barayoga, J. C., Barbieri, C., Barish, B. C., Barker, D., Barneo, P., Barone, F., Barr, B., Barsotti, L., Barsuglia, M., Barta, D., Bartlett, J., Barton, M. A., Bartos, I, Basak, S., Bassiri, R., Basti, A., Bawaj, M., Bayley, J. C., Bazzan, M., Becher, B. R., Becsy, B., Bedakihale, V. M., Beirnaert, F., Bejger, M., Belahcene, I, Benedetto, V, Beniwal, D., Benjamin, M. G., Bennett, T. F., Bentley, J. D., Benyaala, M., Bera, S., Berbel, M., Bergamin, F., Berger, B. K., Bernuzzi, S., Bersanetti, D., Bertolini, A., Betzwieser, J., Beveridge, D., Are, R., Ari, Bhardwaj, U., Bhatt, R., Bhattacharjee, D., Bhaumik, S., Bianchi, A., Bilenko, I. A., Billingsley, G., Bini, S., Birney, R., Birnholtz, O., Biscans, S., Bischi, M., Biscoveanu, S., Bisht, A., Biswas, B., Bitossi, M., Bizouard, M-A, Blackburn, J. K., Blair, C. D., Blair, D. G., Blair, R. M., Bobba, F., Bode, N., Boer, M., Bogaert, G., Boldrini, M., Bolingbroke, G. 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Zhao, C, Zhao, G, Zhao, Y, Zhou, R, Zhou, Z, Zhu, X, Zhu, Z, Zimmerman, A, Zucker, M, Zweizig, J, The LIGO Scientific Collaboration, the Virgo Collaboration, the KAGRA Collaboration, Institut Lumière Matière [Villeurbanne] (ILM), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique 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R., Jaberianhamedan, V., Jacqmin, T., Jacquet, P. -E., Jadhav, S. J., Jadhav, S. P., Jain, T., James, A. L., Jan, A. Z., Jani, K., Janquart, J., Janssens, K., Janthalur, N. N., Jaranowski, P., Jariwala, D., Jaume, R., Jenkins, A. C., Jenner, K., Jeon, C., Jia, W., Jiang, J., Jin, H. -B., Johns, G. R., Johnston, R., Jones, A. W., Jones, D. I., Jones, P., Jones, R., Joshi, P., Ju, L., Jue, A., Jung, P., Jung, K., Junker, J., Juste, V., Kaihotsu, K., Kajita, T., Kakizaki, M., Kalaghatgi, C. V., Kalogera, V., Kamai, B., Kamiizumi, M., Kanda, N., Kandhasamy, S., Kang, G., Kanner, J. B., Kao, Y., Kapadia, S. J., Kapasi, D. P., Karathanasis, C., Karki, S., Kashyap, R., Kasprzack, M., Kastaun, W., Kato, T., Katsanevas, S., Katsavounidis, E., Katzman, W., Kaur, T., Kawabe, K., Kawaguchi, K., Kéfélian, F., Keitel, D., Key, J. S., Khadka, S., Khalili, F. Y., Khan, S., Khanam, T., Khazanov, E. A., Khetan, N., Khursheed, M., Kijbunchoo, N., Kim, A., Kim, C., Kim, J. C., Kim, J., Kim, K., Kim, W. 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Perez, C. ???J., P??rigois, C., Perkins, C. ???C., Perri??s, S., Pfeiffer, H. ???P., Pham, K. ???A., Phukon, K. ???S., Piccinni, O. ???J., Pinto, I., Piotrzkowski, B. ???J., Pitkin, M. ???D., Planas, M. ???L., Pong, D. ???Y. ???T., Porter, E. ???K., Prajapati, A. ???K., Prodi, G. ???A., P??rrer, M., Quinonez, P. ???J., Raab, F. ???J., Rail, S. ???X., Ramirez, K. ???E., Ramirez, T. ???D., Rees, L. ???A., Reid, S. ???W., Reitze, D. ???H., Richardson, J. ???W., Robertson, N. ???A., Rollins, J. ???G., Romel, C. ???L., Romero-Shaw, I. ???M., Romie, J. ???H., Rose, C. ???A., Rosi??ska, D., Ross, M. ???P., Rowlinson, S. ???J., Salafia, O. ???S., Sanchez, E. ???J., Sanchez, J. ???H., Sanchez, L. ???E., Sanders, J. ???R., Saravanan, T. ???R., Savage, R. ???L., Sawant, H. ???L., Schiworski, M. ???G., Schofield, R. ???M. ???S., Sch??nbeck, A., Schulte, B. ???W., Schutz, B. ???F., Scott, S. ???M., Sengupta, A. ???S., Seo, E. ???G., Shahriar, M. ???S., Shaikh, M. ???A., Shcheblanov, N. ???S., 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Al, Ho, Tc, Hohmann, Jn, Holcomb, Dg, Holland, Na, Hollows, Ij, Holmes, Zj, Holz, De, Howell, Ej, Hoy, Cg, Hsieh, Bh, Hsieh, Hf, Huang, Hy, Huang, Yc, Huang, Yj, Huang, Yt, Huang, Yw, Hubner, Mt, Huddart, Ad, Hui, Dcy, Huttner, Sh, Iyer, Br, Jacquet, Pe, Jadhav, Sj, Jadhav, Sp, James, Al, Jan, Az, Janthalur, Nn, Jenkins, Ac, Jin, Hb, Johns, Gr, Jones, Aw, Jones, Di, Kalaghatgi, Cv, Kanner, Jb, Kapadia, Sj, Kapasi, Dp, Khalili, Fy, Khazanov, Ea, Kim, Jc, Kim, Ym, Knee, Am, Knowles, Td, Kong, Akh, Kozak, Db, Krishnendu, Nv, Lam, Tl, Lane, Bb, Lang, Rn, Lasky, Pd, Lecoeuche, Yk, Lee, Hm, Lee, Hw, Legred, In, Leviton, Jn, Li, Aky, Li, Kl, Li, Tgf, Lin, Cy, Lin, Et, Lin, Fk, Lin, Fl, Lin, Hl, Lin, Lcc, Linker, Sd, Linley, Jn, Littenberg, Tb, Liu, Gc, Lo, Rkl, London, Lt, Portilla, Ml, Lott, Tp, Lough, Jd, Lousto, Co, Lucaccioni, Jf, Lundgren, Ap, Luo, Lw, Lynam, Je, Machtinger, Jb, Macleod, Dm, Macmillan, Iao, Hernandez, Im, Magee, Rm, Mansell, Gl, Pina, Dm, Martin, Iw, Martin, Rm, 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Mp, Rowlinson, Sj, Sanchez, Ej, Sanchez, Jh, Sanchez, Le, Sanders, Jr, Saravanan, Tr, Savage, Rl, Sawant, Hl, Schiworski, Mg, Schofield, Rm, Schulte, Bw, Schutz, Bf, Scott, Sm, Seo, Eg, Shaikh, Ma, Shoemaker, Dh, Shoemaker, Dm, Singer, Lp, Singh, Mk, Sintes, Am, Slagmolen, Bjj, Slaven-Blair, Tj, Smith, Jr, Smith, Rje, Somala, Sn, Spencer, Ap, Srivastava, Ak, Steer, Da, Stops, Dj, Strain, Ka, Strang, Lc, Strong, Md, Stuver, Al, Suh, Hg, Sullivan, Ag, Summerscales, Tz, Sutton, Pj, Swinkels, Bl, Tait, Sc, Talbot, Cj, Tanasijczuk, Aj, Tanner, Db, Tapia, Rd, San Martin, Ent, Tasson, Jd, Terhune, Je, Thirugnanasambandam, Mp, Thompson, Ee, Thompson, Je, Thondapu, Sr, Thorne, Ka, Toivonen, Am, Tolley, Ae, Torrie, Ci, Melo, Ite, Tringali, Mc, Trudeau, Rj, Tsang, Kw, Udall, Rp, Urban, Al, van Bakel, N, van Beuzekom, M, van Dael, M, van den Brand, Jfj, Van den Broeck, C, Vander-Hyde, Dc, van Haevermaet, H, van Heijningen, Jv, van Putten, Mhpm, van Remortel, N, Vargas, Af, Veitch, Pj, Vermeulen, Sm, Viets, Ad, Vinet, Jy, von Reis, Erg, von Wrangel, Jsa, Vyatchanin, Sp, Wade, Le, Wagner, Kj, Walet, Rc, Wang, Jz, Wang, Wh, Ward, Rl, Washington, Ny, Weaving, Cr, Webster, Sa, Weinstein, Aj, Weller, Cm, Weller, Ra, Whelan, Jt, White, Dd, Whiting, Bf, Williams, Mj, Williamson, Ar, Willis, Jl, Wilson, Dj, Wipf, Cc, Wofford, Jk, Wong, Icf, Wysocki, Dm, Yang, Fw, Yang, Kz, Yang, Yc, Yap, Mj, Yeeles, Dw, Yeh, Sw, Yelikar, Ab, Yu, Hc, Zendri, Jp, Zhu, Xj, Zhu, Zh, Zimmerman, Ab, Zucker, Me, and (Astro)-Particles Physics
Subjects: Nuclear and High Energy Physics, gravitational wave emission, scalar boson clouds, spinning black holes, ligo o3 data, FOS: Physical sciences, Astronomy & Astrophysics, Physics, Particles & Fields, General Relativity and Quantum Cosmology, Particle dark matter, QC, Particle astrophysic, QB, astro-ph.HE, High Energy Astrophysical Phenomena (astro-ph.HE), Science & Technology, Physics, Classical black hole, SDG 10 - Reduced Inequalities, black holes, Physics and Astronomy, gravitational waves, [SDU]Sciences of the Universe [physics], Physical Sciences, Gravitational wave detection, Gravitational wave source, Astrophysics - High Energy Astrophysical Phenomena
Abstract: This paper describes the first all-sky search for long-duration, quasi-monochromatic gravitational-wave signals emitted by ultralight scalar boson clouds around spinning black holes using data from the third observing run of Advanced LIGO. We analyze the frequency range from 20~Hz to 610~Hz, over a small frequency derivative range around zero, and use multiple frequency resolutions to be robust towards possible signal frequency wanderings. Outliers from this search are followed up using two different methods, one more suitable for nearly monochromatic signals, and the other more robust towards frequency fluctuations. We do not find any evidence for such signals and set upper limits on the signal strain amplitude, the most stringent being $\approx10^{-25}$ at around 130~Hz. We interpret these upper limits as both an "exclusion region" in the boson mass/black hole mass plane and the maximum detectable distance for a given boson mass, based on an assumption of the age of the black hole/boson cloud system., Comment: 28 pages, 16 figures
Published: 2022
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40. Gravitational-wave Constraints on the Equatorial Ellipticity of Millisecond Pulsars

Author: D. Rosińska, Patrice Hello, I. M. Pinto, Stephane Perries, I. La Rosa, Jean-René Cudell, S. Ponrathnam, Chunnong Zhao, G. Pagliaroli, W. Z. Korth, Torrey Cullen, S. H. Huttner, F. Garufi, Rakesh Kumar, Gor Oganesyan, O. Schwarm, Bernard F. Whiting, R. L. Savage, M. Laxen, Anchal Gupta, S. Hochheim, N. A. Robertson, A. F. Brooks, P. J. Quinonez, Andrew Melatos, M. Lorenzini, Surendra Nadh Somala, David Jones, David H. Shoemaker, J. D. Callaghan, Angela Trapananti, H. Rafferty, I. Dorrington, I. Di Palma, J. G. Bartlett, Yu Huang, Geert Raaijmakers, F. Y. Khalili, Q. Chu, J. H. Briggs, Mark Hannam, Marco Cavaglia, Subroto Mukherjee, David Jonathan Hofman, Lindsay DeMarchi, H. Sun, V. JaberianHamedan, Liam Cunningham, V. Kringel, I. M. Romero-Shaw, R. Tso, Jonathan Blackman, Frances Hellman, I. Molina, Jürgen Heinze, P. J. Sutton, Tyson Littenberg, G. Valdes, A. Adams, Laura Cadonati, Ken K. Y. Ng, K. Toland, T. D. Creighton, S. Barnum, R. Kirchhoff, S. P. Jadhav, V. Fafone, Kendall Ackley, R. K. Nayak, H. Y. Chia, A. Strunk, D. Petterson, Pablo Cerdá-Durán, Vivien Raymond, B. Edelman, G. Stolle-McAllister, M. Was, Giacomo Bruno, Sheelu Abraham, J. D. Bentley, I. C. F. Wong, Peter Aufmuth, Tania Regimbau, A. J. Tanasijczuk, L. Mereni, Patrick M. Koch, S. Banagiri, T. L. Lam, José A. Font, Tomasz Bulik, N. Singh, S. B. Anderson, J. Gais, Maya Fishbach, Tim Dietrich, Manel Molina-Ruiz, S. B. Coughlin, M. Mateu-Lucena, Jessica Steinlechner, M. Kolstein, A. Neunzert, D. Fiorucci, C. L. Chan, M. Heurs, A. K. Prajapati, A. R. Wade, M. Patel, Benjamin Stappers, W. Kastaun, H. Qi, J. H. Romie, G. Kuehn, F. J. Raab, Zachariah B. Etienne, N. Mukund, Jennifer Watchi, L. Kleybolte, Daniel R. George, Susan M. Scott, E. K. Porter, V. B. Adya, T. P. Downes, C. Horst, M. Pedraza, F. Muciaccia, A. Lockwood, F. Cavalier, A. Bals, G. Baltus, Karl Gill, V. Srivastava, M. Fays, Santosh Roy, A. Allocca, A. M. Farah, M. F. Carney, A. F. Helmling-Cornell, Ajay Kumar, C. 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Kovalam, Spectroscopies optiques des matériaux verres, amorphes et à nanoparticules (SOPRANO), Institut Lumière Matière [Villeurbanne] (ILM), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Astrophysique Relativiste Théories Expériences Métrologie Instrumentation Signaux (ARTEMIS), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Institut des Fonctions Optiques pour les Technologies de l'informatiON (Institut FOTON), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-École Nationale Supérieure des Sciences Appliquées et de Technologie (ENSSAT)-Centre National de la Recherche Scientifique (CNRS)-Université Bretagne Loire (UBL)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Laboratoire Kastler Brossel (LKB [Collège de France]), Collège de France (CdF (institution))-Sorbonne Université (SU)-Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Laboratoire des matériaux avancés (LMA), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Université Côte d’Azur, Observatoire de la Côte d’Azur, CNRS, Laboratoire Lagrange, Nice, France., Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL), Centre Scientifique de Monaco (CSM), Musee oceanographique de Monaco, Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Istituto Nazionale di Fisica Nucleare, Sezione di Torino (INFN, Sezione di Torino), Istituto Nazionale di Fisica Nucleare (INFN), Museo Storico della Fisica e Centro di Studi e Ricerche 'Enrico Fermi', Roma, Institut des Hautes Etudes Scientifiques (IHES), IHES, Abbott, R., Abbott, T. 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C., Barker, D., Barneo, P., Barnum, S., Barone, F., Barr, B., Barsotti, L., Barsuglia, M., Barta, D., Bartlett, J., Bartos, I., Bassiri, R., Basti, A., Bawaj, M., Bayley, J. C., Bazzan, M., Becher, B. R., Becsy, B., Bedakihale, V. M., Bejger, M., Belahcene, I., Beniwal, D., Benjamin, M. G., Bennett, T. F., Bentley, J. D., Bergamin, F., Berger, B. K., Bergmann, G., Bernuzzi, S., Bersanetti, D., Bertolini, A., Betzwieser, J., Bhandare, R., Bhandari, A. V., Bhattacharjee, D., Bidler, J., Bilenko, I. A., Billingsley, G., Birney, R., Birnholtz, O., Biscans, S., Bischi, M., Biscoveanu, S., Bisht, A., Bitossi, M., Bizouard, M. -A., Blackburn, J. K., Blackman, J., Blair, C. D., Blair, D. G., Blair, R. M., Blanch, O., Bobba, F., Bode, N., Boer, M., Boetzel, Y., Bogaert, G., Boldrini, M., Bondu, F., Bonnand, R., Booker, P., Boom, B. A., Bork, R., Boschi, V., Bose, S., Bossilkov, V., Boudart, V., Bouffanais, Y., Bozzi, A., Bradaschia, C., Brady, P. R., Bramley, A., Branchesi, M., Brau, J. 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L., D'Antonio, S., Danzmann, K., Darsow-Fromm, C., Dasgupta, A., Datrier, L. E. H., Dattilo, V., Dave, I., Davier, M., Davies, G. S., Davis, D., Daw, E. J., Dean, R., Debra, D., Deenadayalan, M., Degallaix, J., De Laurentis, M., Deleglise, S., Del Favero, V., De Lillo, N., Del Pozzo, W., Demarchi, L. M., De Matteis, F., D'Emilio, V., Demos, N., Denker, T., Dent, T., Depasse, A., De Pietri, R., De Rosa, R., De Rossi, C., Desalvo, R., De Varona, O., Dhurandhar, S., Diaz, M. C., Diaz-Ortiz, M., Didio, N. A., Dietrich, T., Di Fiore, L., Difronzo, C., Di Giorgio, C., Di Giovanni, F., Di Giovanni, M., Di Girolamo, T., Di Lieto, A., Ding, B., Di Pace, S., Di Palma, I., Di Renzo, F., Divakarla, A. K., Dmitriev, A., Doctor, Z., D'Onofrio, L., Donovan, F., Dooley, K. L., Doravari, S., Dorrington, I., Downes, T. P., Drago, M., Driggers, J. C., Du, Z., Ducoin, J. -G., Dupej, P., Durante, O., D'Urso, D., Duverne, P. -A., Dwyer, S. E., Easter, P. J., Eddolls, G., Edelman, B., Edo, T. B., Edy, O., Effler, A., Eichholz, J., Eikenberry, S. S., Eisenmann, M., Eisenstein, R. A., Ejlli, A., Errico, L., Essick, R. C., Estelles, H., Estevez, D., Etienne, Z. B., Etzel, T., Evans, M., Evans, T. M., Ewing, B. E., Fafone, V., Fair, H., Fairhurst, S., Fan, X., Farah, A. M., Farinon, S., Farr, B., Farr, W. M., Fauchon-Jones, E. J., Favata, M., Fays, M., Fazio, M., Feicht, J., Fejer, M. M., Feng, F., Fenyvesi, E., Ferguson, D. L., Fernandez-Galiana, A., Ferrante, I., Ferreira, T. A., Fidecaro, F., Figura, P., Fiori, I., Fiorucci, D., Fishbach, M., Fisher, R. P., Fishner, J. M., Fittipaldi, R., Fitz-Axen, M., Fiumara, V., Flaminio, R., Floden, E., Flynn, E., Fong, H., Font, J. A., Forsyth, P. W. F., Fournier, J. -D., Frasca, S., Frasconi, F., Frei, Z., Freise, A., Frey, R., Frey, V., Fritschel, P., Frolov, V. V., Fronze, G. G., Fulda, P., Fyffe, M., Gabbard, H. A., Gadre, B. U., Gaebel, S. M., Gair, J. 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Z., Hammond, G., Haney, M., Hanke, M. M., Hanks, J., Hanna, C., Hannam, M. D., Hannuksela, O. A., Hannuksela, O., Hansen, H., Hansen, T. J., Hanson, J., Harder, T., Hardwick, T., Haris, K., Harms, J., Harry, G. M., Harry, I. W., Hartwig, D., Hasskew, R. K., Haster, C. -J., Haughian, K., Hayes, F. J., Healy, J., Heidmann, A., Heintze, M. C., Heinze, J., Heinzel, J., Heitmann, H., Hellman, F., Hello, P., Helmling-Cornell, A. F., Hemming, G., Hendry, M., Heng, I. S., Hennes, E., Hennig, J., Hennig, M. H., Vivanco, F. H., Heurs, M., Hild, S., Hill, P., Hines, A. S., Hochheim, S., Hofgard, E., Hofman, D., Hohmann, J. N., Holgado, A. M., Holland, N. A., Hollows, I. J., Holmes, Z. J., Holt, K., Holz, D. E., Hopkins, P., Horst, C., Hough, J., Howell, E. J., Hoy, C. G., Hoyland, D., Huang, Y., Hubner, M. T., Huddart, A. D., Huerta, E. A., Hughey, B., Hui, V., Husa, S., Huttner, S. H., Hutzler, B. M., Huxford, R., Huynh-Dinh, T., Idzkowski, B., Iess, A., Imperato, S., Inchauspe, H., Ingram, C., Intini, G., Isi, M., Iyer, B. R., Jaberianhamedan, V., Jacqmin, T., Jadhav, S. J., Jadhav, S. P., James, A. L., Jani, K., Janssens, K., Janthalur, N. N., Jaranowski, P., Jariwala, D., Jaume, R., Jenkins, A. C., Jeunon, M., Jiang, J., Johns, G. R., Jones, A. W., Jones, D. I., Jones, J. D., Jones, P., Jones, R., Jonker, R. J. G., Ju, L., Junker, J., Kalaghatgi, C. V., Kalogera, V., Kamai, B., Kandhasamy, S., Kang, G., Kanner, J. B., Kapadia, S. J., Kapasi, D. P., Karathanasis, C., Karki, S., Kashyap, R., Kasprzack, M., Kastaun, W., Katsanevas, S., Katsavounidis, E., Katzman, W., Kawabe, K., Kefelian, F., Keitel, D., Key, J. S., Khadka, S., Khalili, F. Y., Khan, I., Khan, S., Khazanov, E. A., Khetan, N., Khursheed, M., Kijbunchoo, N., Kim, C., Kim, G. J., Kim, J. C., Kim, K., Kim, W., Kim, W. S., Kim, Y. -M., Kimball, C., King, P. J., Kinley-Hanlon, M., Kirchhoff, R., Kissel, J. S., Kleybolte, L., Klimenko, S., Knowles, T. D., Knyazev, E., Koch, P., Koehlenbeck, S. M., Koekoek, G., Koley, S., Kolstein, M., Komori, K., Kondrashov, V., Kontos, A., Koper, N., Korobko, M., Korth, W. Z., Kovalam, M., Kozak, D. B., Kramer, C., Kringel, V., Krishnendu, N. V., Krolak, A., Kuehn, G., Kumar, A., Kumar, P., Kumar, R., Kuns, K., Kwang, S., Lackey, B. D., Laghi, D., Lalande, E., Lam, T. L., Lamberts, A., Landry, M., Lane, B. B., Lang, R. N., Lange, J., Lantz, B., Lanza, R. K., Rosa, I. L., Lartaux-Vollard, A., Lasky, P. D., Laxen, M., Lazzarini, A., Lazzaro, C., Leaci, P., Leavey, S., Lecoeuche, Y. K., Lee, H. M., Lee, H. W., Lee, J., Lee, K., Lehmann, J., Leon, E., Leroy, N., Letendre, N., Levin, Y., Li, A., Li, J., Li, K. J. L., Li, T. G. F., Li, X., Linde, F., Linker, S. D., Linley, J. N., Littenberg, T. B., Liu, J., Liu, X., Llorens-Monteagudo, M., Lo, R. K. L., Lockwood, A., London, L. T., Longo, A., Lorenzini, M., Loriette, V., Lormand, M., Losurdo, G., Lough, J. D., Lousto, C. O., Lovelace, G., Lower, M., Luck, H., Lumaca, D., Lundgren, A. P., Ma, Y., Macas, R., Macinnis, M., Macleod, D. M., Macmillan, I. A. O., Macquet, A., Magana Hernandez, I., Magana-Sandoval, F., Magazzu, C., Magee, R. M., Majorana, E., Maksimovic, I., Maliakal, S., Malik, A., Man, N., Mandic, V., Mangano, V., Mansell, G. L., Manske, M., Mantovani, M., Mapelli, M., Marchesoni, F., Marion, F., Marka, S., Marka, Z., Markakis, C., Markosyan, A. S., Markowitz, A., Maros, E., Marquina, A., Marsat, S., Martelli, F., Martin, I. W., Martin, R. M., Martinez, M., Martinez, V., Martynov, D. V., Masalehdan, H., Mason, K., Massera, E., Masserot, A., Massinger, T. J., Masso-Reid, M., Mastrogiovanni, S., Matas, A., Mateu-Lucena, M., Matichard, F., Matiushechkina, M., Mavalvala, N., Maynard, E., Mccann, J. J., Mccarthy, R., Mcclelland, D. E., Mccormick, S., Mcculler, L., Mcguire, S. C., Mcisaac, C., Mciver, J., Mcmanus, D. J., Mcrae, T., Mcwilliams, S. T., Meacher, D., Meadors, G. 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Lasky, Pd, Lecoeuche, Yk, Lee, Hm, Lee, Hw, Li, Kjl, Li, Tgf, Linker, Sd, Linley, Jn, Littenberg, Tb, Lo, Rkl, London, Lt, Lough, Jd, Lousto, Co, Lundgren, Ap, Macleod, Dm, Macmillan, Iao, Hernandez, Im, Magee, Rm, Mansell, Gl, Martin, Iw, Martin, Rm, Martynov, Dv, Massinger, Tj, Mccann, Jj, Mcclelland, De, Mcguire, Sc, Mcmanus, Dj, Mcwilliams, St, Meadors, Gd, Mehta, Ak, Melchor, Da, Mercer, Ra, Merilh, El, Merritt, Jd, Meyers, Pm, Miller, Al, Mills, Jc, Milovich-Goff, Mc, Mir, Lm, Mitrofanov, Vp, Mohapatra, Srp, Mohite, Sr, Moore, Cj, Mow-Lowry, Cm, Muniz, Ea, Murray, Pg, Nadji, Sl, Nayak, Rk, Neil, Bf, Nelson, Tjn, Ng, Ky, Nichols, Sa, Nuttall, Lk, Ogin, Gh, Oh, Jj, Oh, Sh, Okada, Ma, Oram, Rj, Ormiston, Rg, Ortega, Lf, Ottaway, Dj, Owen, Bj, Pace, Ae, Page, Ma, Pai, Sa, Palamos, Jr, Panda, Pk, Pang, Th, Pant, Bc, Pechsiri, Tc, Perez, Cj, Pfeiffer, Hp, Pham, Ka, Piccinni, Oj, Pinto, Im, Pong, Dyt, Porter, Ek, Prajapati, Ak, Prodi, Ga, Quinonez, Pj, Raab, Fj, Rail, Sx, Ramirez, Ke, 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D., O’Dell, J., O’Reilly, B., O’Shaughnessy, R., Périgois, C., Perriès, S., Pinto, I. M., Pürrer, M., Rosińska, D., Roy, Santosh, Roy, Soumen, Schönbeck, A., Stolle-McAllister, G., Südbeck, J., Szczepańczyk, M. J., San Martin, E. N. Tapia, Tiwari, Shubhanshu, Tiwari, Srishti, Torres-Forné, A., e Melo, I. Tosta, Töyrä, D., Bakel, N. van, Beuzekom, M. van, van den Brand, J. F. J., Broeck, C. Van Den, Schaaf, L. van der, Heijningen, J. V. van, Vasúth, M., Viceré, A., Weßels, P., Yu, Hang, Yu, Haocun, Zadrożny, A., RS: FSE Grav. waves and fundamental physics, Grav. waves and fundamental physics, Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-École Nationale Supérieure des Sciences Appliquées et de Technologie (ENSSAT)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Collège de France (CdF (institution)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Joseph Louis LAGRANGE (LAGRANGE), Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Observatoire de la Côte d'Azur (OCA), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), LIGO Scientific, Virgo, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-École Nationale Supérieure des Sciences Appliquées et de Technologie (ENSSAT)-Centre National de la Recherche Scientifique (CNRS), Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Collège de France (CdF (institution))-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut des Hautes Études Scientifiques (IHES), The LIGO Scientific Collaboration, The Virgo Collaboration, and Van Swinderen Institute for Particle Physics and G
Subjects: Gravitational waves, Neutron stars, Pulsars, Gravitational wave sources, 010504 meteorology & atmospheric sciences, Astronomy, Astrophysics, Vela, 01 natural sciences, General Relativity and Quantum Cosmology, [SPI]Engineering Sciences [physics], neutron, Millisecond pulsar, emission, 010303 astronomy & astrophysics, QC, QB, Settore FIS/01, Physics, astro-ph.HE, High Energy Astrophysical Phenomena (astro-ph.HE), [PHYS]Physics [physics], Astrophysics::Instrumentation and Methods for Astrophysics, [PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc], Astrophysics - High Energy Astrophysical Phenomena, Gravitational-Waves, Pulsars, Neutron Stars, Gravitational wave, PROPER MOTION, Proper motion, gr-qc, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, Neutron star, General Relativity and Quantum Cosmology (gr-qc), Gravitational-Waves, SEARCHES, Settore FIS/05 - Astronomia e Astrofisica, Pulsar, 0103 physical sciences, [CHIM]Chemical Sciences, Astrophysique, STFC, Astrophysics::Galaxy Astrophysics, 0105 earth and related environmental sciences, crab pulsar, Crab Pulsar, RCUK, Astronomy and Astrophysics, Neutron Stars, Gravitational waves, Neutron stars, Pulsars, Gravitational wave sources, LIGO, Space and Planetary Science, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Abstract: We present a search for continuous gravitational waves from five radio pulsars, comprising three recycled pulsars (PSR J0437-4715, PSR J0711-6830, and PSR J0737-3039A) and two young pulsars: the Crab pulsar (J0534+2200) and the Vela pulsar (J0835-4510). We use data from the third observing run of Advanced LIGO and Virgo combined with data from their first and second observing runs. For the first time, we are able to match (for PSR J0437-4715) or surpass (for PSR J0711-6830) the indirect limits on gravitational-wave emission from recycled pulsars inferred from their observed spin-downs, and constrain their equatorial ellipticities to be less than 10-8. For each of the five pulsars, we perform targeted searches that assume a tight coupling between the gravitational-wave and electromagnetic signal phase evolution. We also present constraints on PSR J0711-6830, the Crab pulsar, and the Vela pulsar from a search that relaxes this assumption, allowing the gravitational-wave signal to vary from the electromagnetic expectation within a narrow band of frequencies and frequency derivatives., 0, info:eu-repo/semantics/published
Published: 2020
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41. Work-Related Musculoskeletal Disorders in Endoscopic Sinus and Skull Base Surgery: A Systematic Review With Meta-analysis.

Author: Campbell RG, Zadro JR, Gamble AR, Chan CL, Mackey MG, Osie G, Png LH, Douglas RG, and Pappas E
Subjects: Humans, Prevalence, Ergonomics, Endoscopy, Occupational Diseases epidemiology, Skull Base surgery, Musculoskeletal Diseases epidemiology
Abstract: Objective: Endoscopic sinus and skull base surgery has led to significant improvements in patient outcomes, yet may have come at a cost to surgeons' musculoskeletal (MSK) health. We aimed to determine the prevalence and characteristics of work-related MSK disorders (WRMDs) in endoscopic sinus and skull base surgeons; to investigate contributing factors for WRMD in this population; and to evaluate the effectiveness of ergonomic interventions on the severity or prevalence of WRMD in this population., Data Sources: Medline, Embase, CINAHL, Web of Science, and Scopus from inception to April 2, 2024. A bibliographic examination was performed for further papers., Review Methods: Inclusion criteria included original peer-reviewed papers with work-related MSK outcomes (prevalence, contributing factors, and interventions) relating to endoscopic sinus and/or skull base surgeons in any language., Results: Of 25,772 unique citations, 37 studies met the inclusion criteria. The pooled lifetime, point, and 12-month prevalences of WRMD were 75.9% (95% confidence interval; I 2 , 67.2%-83.6%, I 2 95.6%), 80.8% (77.0%-84.3%, I 2 98.0%), and 82.0% (71.8%-90.3%, I 2 60.96%) respectively. The neck, lumbar spine, and thoracic spine were the most commonly involved areas. One of 9 studies on contributing factors investigated discomfort as an outcome. The remainder focussed on surrogate outcomes (eg, posture, hand dysfunction). Two of the 13 intervention studies investigated pain or fatigue as an outcome. The remainder targeted posture, muscle activity, or workload., Conclusion: WRMDs are highly prevalent in endoscopic sinus and skull base surgeons. Further studies focusing on the direct outcomes of WRMD such as pain are needed., (© 2024 The Author(s). Otolaryngology–Head and Neck Surgery published by Wiley Periodicals LLC on behalf of American Academy of Otolaryngology–Head and Neck Surgery Foundation.)
Published: 2024
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42. A website for cluster randomised trials including stepped wedge: facilitating quality trials and methodological research.

Author: Chan CL, Leyrat C, Martin J, Thompson J, Turner EL, and Eldridge SM
Subjects: Humans, Cluster Analysis, Randomized Controlled Trials as Topic methods, Research Design, Internet
Abstract: Background: A cluster randomised trial is a randomised controlled trial in which groups of individuals (clusters) are randomised to treatment arms. Stepped wedge cluster randomised trials are a type of cluster randomised trial where clusters are randomised to sequences. These trial designs are important for impacting decision-making, and it is therefore important that they be well-conducted and reported., Main Body: In November 2018, we created a new website dedicated to cluster randomised trials, including stepped wedge designs: https://clusterrandomisedtrials.qmul.ac.uk/ . The idea for the website emerged from the conference on Current Developments in Cluster Randomised Trials and Stepped Wedge Designs held in November 2016 at Queen Mary University of London, with the aim to provide an online resource to facilitate quality trials and methodological research on these types of trial. The website is divided into sections covering Design, Analysis and Reporting for traditional (i.e. parallel two-arm) cluster randomised trials and stepped wedge designs and contains resources in the form of hyperlinks to relevant papers along with brief explanations. A noticeboard page provides details on announcements, events, and past events., Conclusion: We aim to keep the site updated with the latest publications and events related to cluster randomised trials, and welcome suggestions from the research community on further resources or events to add. We hope that the site will facilitate high-quality traditional and stepped wedge cluster randomised trials., (© 2024. The Author(s).)
Published: 2024
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43. Prevalence and key determinants of the triple burden of childhood malnutrition in Southeast Asian countries: a systematic review and meta-analysis within an adapted socio-ecological framework.

Author: Tan PY, Chan CL, Som SV, Dye L, Moore JB, Caton S, and Gong Y
Abstract: The triple burden of malnutrition (TBM) is increasing globally, but significant evidence gaps exist regarding its burden and drivers among children in Southeast Asian (SEA) countries. We systematically searched four databases (PROSPERO-CRD42023420129) and Google Scholar through February 2024. We assessed stunting and overweight prevalence among children aged 0-18 years old across four SEA countries (Indonesia, Malaysia, Thailand, and Vietnam) from recent national surveys. We conducted random-effect meta-analyses to estimate the pooled prevalence of micronutrient deficiencies, and the pooled odds ratio for TBM-associated determinants using an adapted socio-ecological framework. 176 studies were included for systematic review, with 132 studies eligible for meta-analysis. Our findings illustrate significant variation in TBM across countries, dependent on region, age, and sex. Pooled prevalence [95% CI] of anemia, iron, vitamin A, and D deficiencies were 25% [22, 29], 14% [10, 18], 6% [4, 8], and 40% [32, 48], respectively (I 2 >90%). Determinants of the TBM included child-individual factors, poor early-life nutrition, and family household characteristics including maternal nutrition and education, socioeconomic, family size, sanitation, and food security. However, macro-level environmental impacts were less documented. Our findings emphasize the need for robust, timely monitoring of TBM data, including micronutrient biomarkers, and targeted policy intervention in SEA countries.
Published: 2024
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44. Control of innate olfactory valence by segregated cortical amygdala circuits.

Author: Howe JR, Chan CL, Lee D, Blanquart M, Lee JH, Romero HK, Zadina AN, Lemieux ME, Mills F, Desplats PA, Tye KM, and Root CM
Abstract: Animals exhibit innate behaviors that are stereotyped responses to specific evolutionarily relevant stimuli in the absence of prior learning or experience. These behaviors can be reduced to an axis of valence, whereby specific odors evoke approach or avoidance responses. The posterolateral cortical amygdala (plCoA) mediates innate attraction and aversion to odor. However, little is known about how this brain area gives rise to behaviors of opposing motivational valence. Here, we sought to define the circuit features of plCoA that give rise to innate attraction and aversion to odor. We characterized the physiology, gene expression, and projections of this structure, identifying a divergent, topographic organization that selectively controls innate attraction and avoidance to odor. First, we examined odor-evoked responses in these areas and found sparse encoding of odor identity, but not valence. We next considered a topographic organization and found that optogenetic stimulation of the anterior and posterior domains of plCoA elicits attraction and avoidance, respectively, suggesting a functional axis for valence. Using single cell and spatial RNA sequencing, we identified the molecular cell types in plCoA, revealing an anteroposterior gradient in cell types, whereby anterior glutamatergic neurons preferentially express VGluT2 and posterior neurons express VGluT1 . Activation of these respective cell types recapitulates appetitive and aversive behaviors, and chemogenetic inhibition reveals partial necessity for responses to innate appetitive or aversive odors. Finally, we identified topographically organized circuits defined by projections, whereby anterior neurons preferentially project to medial amygdala, and posterior neurons preferentially project to nucleus accumbens, which are respectively sufficient and necessary for innate attraction and aversion. Together, these data advance our understanding of how the olfactory system generates stereotypic, hardwired attraction and avoidance, and supports a model whereby distinct, topographically distributed plCoA populations direct innate olfactory responses by signaling to divergent valence-specific targets, linking upstream olfactory identity to downstream valence behaviors, through a population code. This suggests a novel amygdala circuit motif in which valence encoding is represented not by the firing properties of individual neurons, but by population level identity encoding that is routed through divergent targets to mediate distinct behaviors of opposing appetitive and aversive responses., Competing Interests: DECLARATION OF INTERESTS The authors declare no competing interests.
Published: 2024
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45. The Orbitofrontal Cortex Is Required for Learned Modulation of Innate Olfactory Behavior.

Author: Miyamoto K, Stark J, Kathrotia M, Luu A, Victoriano J, Chan CL, Lee D, and Root CM
Subjects: Animals, Male, Mice, Olfactory Perception physiology, Mice, Inbred C57BL, Instinct, Smell physiology, Mice, Transgenic, Proto-Oncogene Proteins c-fos metabolism, Behavior, Animal physiology, Prefrontal Cortex physiology, Optogenetics, Odorants
Abstract: Animals have evolved innate responses to cues including social, food, and predator odors. In the natural environment, animals are faced with choices that involve balancing risk and reward where innate significance may be at odds with internal need. The ability to update the value of a cue through learning is essential for navigating changing and uncertain environments. However, the mechanisms involved in this modulation are not well defined in mammals. We have established a new olfactory assay that challenges a thirsty mouse to choose an aversive odor over an attractive odor in foraging for water, thus overriding their innate behavioral response to odor. Innately, mice prefer the attractive odor port over the aversive odor port. However, decreasing the probability of water at the attractive port leads mice to prefer the aversive port, reflecting a learned override of the innate response to the odors. The orbitofrontal cortex (OFC) is a fourth-order olfactory brain area, involved in flexible value association, with behaviorally relevant outputs throughout the limbic system. We performed optogenetic and chemogenetic silencing experiments that demonstrate the OFC is necessary for this learned modulation of innate aversion to odor. Further, we characterized odor evoked c-fos expression in learned and control mice and found significant suppression of activity in the bed nucleus of the stria terminalis, lateral septum, and central and medial amygdala. These findings reveal that the OFC is necessary for the learned override of innate behavior and may signal to limbic structures to modulate innate response to odor., Competing Interests: The authors declare no competing financial interests., (Copyright © 2024 Miyamoto et al.)
Published: 2024
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46. Anaphylaxis post-COVID-19 vaccinations in Singapore.

Author: Peck LF, Poh WW, Lim AT, Soh SBL, Tham MY, Foo BPQ, Ng AJJ, Ng PSL, Ang PS, Chan CL, Toh DSL, Lee EJD, Santosa A, Thong BY, Bever HV, Lee HY, Sum CF, Dorajoo SR, and Teo DCH
Abstract: Introduction: Anaphylaxis was the first serious adverse event (AE) of special interest surfaced in Singapore following coronavirus disease 2019 (COVID-19) vaccination. Individuals who developed physician-diagnosed severe allergic reactions to the mRNA vaccines would be medically ineligible for mRNA vaccines and offered non-mRNA alternatives. This paper describes anaphylaxis reports received by the Health Sciences Authority (HSA) and presents a review of individuals who received heterologous COVID-19 vaccination., Methods: Reports of anaphylaxis associated with the COVID-19 vaccines received till 31 July 2022 were reviewed and adjudicated using the Brighton Collaboration case definition criteria by an HSA-appointed expert panel. Additional review was conducted for cases with heterologous vaccination for any subsequent reactions until administration of third dose of COVID-19 vaccines., Results: Among 112 adjudicated anaphylaxis cases, majority occurred in females, adults and persons with allergy histories, which were consistent with global observations. Most cases (71%) occurred within 30 minutes of vaccination. The reporting incidence rates (IRs) of 0.67 and 0.55 per 100,000 administered doses for Comirnaty and Spikevax vaccines, respectively, were comparable with IRs reported overseas, whereas the IRs for non-mRNA vaccines (Sinovac-CoronaVac and Nuvaxovid) were much higher at 4.14 and 29.82 per 100,000 administered doses, respectively, likely due to selection bias. Review of the 20 cases following heterologous vaccination found varying reactions to subsequent vaccinations., Conclusion: Anaphylaxis is a rare but serious AE in which outcomes can be mitigated with timely medical intervention. The case review helped to guide vaccination strategies and added to the cumulative knowledge of safety with heterologous vaccination., (Copyright © 2024 Copyright: © 2024 Singapore Medical Journal.)
Published: 2024
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47. Multiple Roads to Success: A Latent Class Analysis on Successful Ageing Among Hong Kong Near-Centenarians and Centenarians (NCC).

Author: Shum EN, Lau BH, Cheung KS, Chan CL, Siu JC, Luk JK, Kwan JS, Chan GM, Pat LY, and Martin P
Subjects: Humans, Hong Kong epidemiology, Female, Male, Aged, 80 and over, Independent Living statistics & numerical data, Aging psychology, Health Status, Healthy Aging, Frailty epidemiology, Longevity, Geriatric Assessment statistics & numerical data, Geriatric Assessment methods, Cognition, Latent Class Analysis, Caregivers statistics & numerical data
Abstract: Notwithstanding the oldest-old cohort being the fastest-growing population in most ageing societies, characterizing successful ageing in adults of advanced age, such as nonagenarians and centenarians, remains challenging. This study investigated the successful ageing subphenotypes using the data from Hong Kong Centenarian Study 2. Between April 2021 and September 2022, 146 family caregivers of community-dwelling older adults aged 95 or above were interviewed by phone. Latent class analysis identified three classes- Overall Frail (46.6%) with poor mobility, cognitive and functional health, Nonambulant (37.0%) but good functional health, and Robust (16.4%) with overall good health-from 11 indicators based on caregivers' reports. Although we found a low prevalence of fulfillment of all indicators of successful ageing, our findings will help care professionals appreciate the heterogeneity underlying partial successful ageing in this vulnerable cohort for segmented and targeted healthy longevity interventions., Competing Interests: Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Published: 2024
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48. The Effects of Masked and Delayed Auditory Feedback on Fundamental Frequency Modulation in Vocal Vibrato.

Author: Lester-Smith RA, Hilger A, Dunne-Platero KE, Kim JH, Chan CL, and Larson CR
Subjects: Humans, Male, Female, Adult, Time Factors, Young Adult, Feedback, Sensory, Acoustic Stimulation, Noise adverse effects, Bayes Theorem, Acoustics, Speech Acoustics, Perceptual Masking, Voice Quality, Singing
Abstract: Purpose: Although relatively precise control over the extent and rate of fundamental frequency (f o ) modulation may be needed for optimal production of vibrato, the role of auditory feedback in controlling vibrato is not well understood. Previous studies altered the gain and timing of auditory feedback in singers producing vibrato and showed inconsistent effects on the extent and rate of f o modulation, which may have been related to small sample sizes or limited analyses. Therefore, the purpose of this study was to further investigate whether the gain or timing of auditory feedback impacts control of vibrato in a larger sample of speakers and with advanced statistical analyses., Method: Ten classically-trained singers produced sustained vowels with vibrato while their auditory feedback was masked with pink noise or multi-talker babble to reduce the gain of their auditory feedback and while their auditory feedback was delayed by about 200 or 300 milliseconds to alter the timing of their auditory feedback. Acoustical analyses measured changes in the extent and rate of f o modulation in the masked and delayed trials relative to control trials. Bayesian modeling was used to analyze the effects of noise-masked, babble-masked, and delayed auditory feedback on the extent and rate of f o modulation., Results: There was compelling evidence that noise masking increased the extent of f o modulation, and babble masking increased the variability in the rate of f o modulation (ie, jitter of f o modulation). Masked auditory feedback did not affect the average rate of f o modulation. Delayed auditory feedback did not affect the extent, rate, or jitter of f o modulation., Conclusions: The current study demonstrated that reducing the gain of the auditory feedback with noise masking increased the extent of f o modulation but did not affect the average rate of f o modulation in classically-trained singers producing vibrato. Reducing the gain of the auditory feedback with babble masking and altering the timing of auditory feedback with imposed delays did not affect the average extent or rate of f o modulation. However, babble masking increased the jitter of f o modulation rate, which suggests that modulated auditory feedback may affect the periodicity of f o modulation from one modulation cycle to the next. These findings clarify the role of auditory feedback in controlling vibrato and may inform the current reflex-resonance models of vibrato., (Copyright © 2022 The Voice Foundation. Published by Elsevier Inc. All rights reserved.)
Published: 2024
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49. Mechanistic insights into bismuth(iii) inhibition of SARS-CoV-2 helicase.

Author: Wei X, Chan CL, Zhou Y, Tang K, Chen J, Wang S, Chan JF, Yuan S, Li H, and Sun H
Abstract: The COVID-19 pandemic caused by SARS-CoV-2 resulted in a global public health crisis. In addition to vaccines, the development of effective therapy is highly desirable. Targeting a protein that plays a critical role in virus replication may allow pan-spectrum antiviral drugs to be developed. Among SARS-CoV-2 proteins, helicase ( i.e. , non-structural protein 13) is considered as a promising antiviral drug target due to its highly conserved sequence, unique structure and function. Herein, we demonstrate SARS-CoV-2 helicase as a target of bismuth-based antivirals in virus-infected mammalian cells by a metal-tagged antibody approach. To search for more potent bismuth-based antivirals, we further screened a panel of bismuth compounds towards inhibition of ATPase and DNA unwinding activity of nsp13 and identified a highly potent bismuth compound Bi(5-aminotropolonate) 3 , namely Bi(Tro-NH 2 ) 3 with an IC 50 of 30 nM for ATPase. We show that bismuth-based compounds inhibited nsp13 unwinding activity via disrupting the binding of ATP and the DNA substrate to viral helicase. Binding of Bi(iii) to nsp13 also abolished the interaction between nsp12 and nsp13 as evidenced by immunofluorescence and co-immunoprecipitation assays. Finally, we validate our in vitro data in SARS-CoV-2 infected mammalian cells. Notably, Bi(6-TG) 3 exhibited an EC 50 of 1.18 ± 0.09 μM with a selective index of 847 in VeroE6-TMPRSS2 infected cells. This study highlights the important role of helicase for the development of more effective antiviral drugs to combat SARS-CoV-2 infection., Competing Interests: There are no conflicts to declare., (This journal is © The Royal Society of Chemistry.)
Published: 2024
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50. The Problems with Online Health Product Sales: How can Regulations be Improved?

Author: Sng YJ, Kwok D, Goh E, Tan A, Teo J, and Chan CL
Subjects: Humans, Internet, Commerce legislation & jurisprudence
Abstract: With the rapid proliferation of online businesses, national authorities are facing challenges managing the online supply of illegal health products due to the anonymity of the internet, increasing number of global syndicates, new technologies, and inability to enforce against overseas sellers. This paper describes these challenges and the Health Sciences Authority's regulatory approaches to tackle the online sales of illegal health products. These include partnering with platform administrators to remove illegal online postings, leveraging technological tools and relevant legislation, empowering consumers to make informed decisions, and fostering closer collaborations across different jurisdictions to combat online pharmaceutical crimes., (© 2024. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
Published: 2024
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