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Your search keyword '"Chamorro-Cevallos, German"' showing total 27 results
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27 results on '"Chamorro-Cevallos, German"'

3. Phytochemicals and Their Usefulness in the Maintenance of Health

Author

Rodríguez-Negrete, Elda Victoria, primary, Morales-González, Ángel, additional, Madrigal-Santillán, Eduardo Osiris, additional, Sánchez-Reyes, Karina, additional, Álvarez-González, Isela, additional, Madrigal-Bujaidar, Eduardo, additional, Valadez-Vega, Carmen, additional, Chamorro-Cevallos, German, additional, Garcia-Melo, Luis Fernando, additional, and Morales-González, José A., additional

Published
2024
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10. Synthesis and highly potent hypolipidemic activity of alpha-asarone- and fibrate-based 2-acyl and 2-alkyl phenols as HMG-CoA reductase inhibitors

Author

Mendieta, Aarón, Jiménez, Fabiola, Garduño-Siciliano, Leticia, Mojica-Villegas, Angélica, Rosales-Acosta, Blanca, Villa-Tanaca, Lourdes, Chamorro-Cevallos, Germán, Medina-Franco, José L., Meurice, Nathalie, Gutiérrez, Rsuini U., Montiel, Luisa E., Cruz, María del Carmen, and Tamariz, Joaquín

Published
2014
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12. Development, Characterization, Optimization, and In Vivo Evaluation of Methacrylic Acid–Ethyl Acrylate Copolymer Nanoparticles Loaded with Glibenclamide in Diabetic Rats for Oral Administration

Author

Guadarrama-Escobar, Omar Rodrigo, primary, Sánchez-Vázquez, Ivonne, additional, Serrano-Castañeda, Pablo, additional, Chamorro-Cevallos, German Alberto, additional, Rodríguez-Cruz, Isabel Marlen, additional, Sánchez-Padrón, Adalí Yisell, additional, Anguiano-Almazán, Ericka, additional, Peña-Juárez, Ma. Concepción, additional, Méndez-Albores, Abraham, additional, Domínguez-Delgado, Clara Luisa, additional, Mercado-Márquez, Crisóforo, additional, Rodríguez-Pérez, Betsabé, additional, and Escobar-Chávez, José Juan, additional

Published
2021
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21. Neuroprotective effect of Spirulina (Arthrospira) maxima against kainic acid-induced neurotoxicity

Author

Chamorro-Cevallos German, Alva-Sanchez Claudia, Perez-Juarez Angelica, Pacheco-Rosado Jorge, and Paniagua-Castro Norma

Subjects
Pharmacology, Kainic acid, Antioxidant, biology, medicine.medical_treatment, Neurotoxicity, Pharmaceutical Science, Plant Science, medicine.disease, biology.organism_classification, medicine.disease_cause, Neuroprotection, Lipid peroxidation, chemistry.chemical_compound, Complementary and alternative medicine, chemistry, Biochemistry, Drug Discovery, medicine, Spirulina (dietary supplement), Arthrospira, Oxidative stress
Abstract

Oxidative stress has been implicated in the pathophysiology of neurologic disorders and brain dysfunctions. Spirulina (Arthrospira) maxima (SP) is a cyanobacteria with nutritional, pharmacological and important antioxidant activity. This study aims to evaluate the neuroprotective role of SP against kainic acid (KA) neurotoxicity. Male SW mice were treated with SP for 24 days (200, 400 and 800 mg/kg, (o.v.) and KA (35 mg/kg) was intraperitoneally administered as a single dose on day 14. After the treatment, neurobehavioral changes were monitored and lipid peroxidation in hippocampus was studied as an index of oxidative stress. These studies indicate that SP treatment reduced oxidative stress and protected against the damaging neurobehavioral effects of KA, suggesting it could be a possible alternative in treating neurodegenerative diseases. Key words: Hippocampus, kainic acid, neurobehavioral effects, neuroprotection, Spirulina.

Published
2012

26. NUTRITIONAL AND TOXICOLOGICAL ASPECTS OF SPIRULINA (ARTHROSPIRA).

Author

Gutiérrez-Salmeán, Gabriela, Fabila-Castillo, Luis, Chamorro-Cevallos, Germán, and Chamorro-Cevallos, German

Subjects
*SPIRULINA, *FUNCTIONAL foods, *NUTRITIONAL value, *NUTRITIONAL assessment, *FOOD toxicology
Abstract

Undernutrition constitutes a public health problem particularly in developing countries. The utilization of algae, particularly Spirulina, as a functional food was suggested decades ago due to the fact that it is not only a protein-dense food source, but because its amino acid profile is considered as of high biologic-value protein content. Spirulina provides essential fats (e.g., gamma-linolenic oleic acids), concomitant to low content nucleic acids. It also has an exceptionally high content of vitamin B12, is a good source of beta-carotene, iron, calcium and phosphorous. Moreover, Spirulina has also proven to have good acceptance as of its organoleptic properties (thus making it a possible prospect for food or a nutrition supplement) and it has not exhibited neither acute nor chronic toxicities, making it safe for human consumption. [ABSTRACT FROM AUTHOR]

Published
2015
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27. Effects of (-)-epicatechin on a diet-induced rat model of cardiometabolic risk factors.

Author

Gutiérrez-Salmeán G, Ortiz-Vilchis P, Vacaseydel CM, Garduño-Siciliano L, Chamorro-Cevallos G, Meaney E, Villafaña S, Villarreal F, Ceballos G, and Ramírez-Sánchez I

Subjects
Animals, Blood Glucose metabolism, Blood Pressure drug effects, Catechin administration & dosage, Disease Models, Animal, Eating drug effects, Feces chemistry, Heart Diseases etiology, Heart Diseases metabolism, Male, Obesity complications, Obesity metabolism, Rats, Rats, Wistar, Risk Factors, Triglycerides blood, Weight Gain drug effects, Catechin therapeutic use, Diet, High-Fat adverse effects, Energy Metabolism drug effects, Heart Diseases prevention & control, Obesity drug therapy
Abstract

Overweight and obesity have been associated with increase in cardiometabolic risk. Therapeutics include lifestyle changes and/or pharmacologic agents. However, such interventions are often limited by poor compliance and/or significant side effects. The consumption of certain dietary products, such as cocoa, exerts positive effects on cardiometabolic risk factors. (-)-Epicatechin (EPI), the most abundant flavonoid in cacao has been reported to replicate such effects. However its mechanisms of action have not been fully elucidated.In a rat model of high-fat diet-induced obesity and its associated cardiometabolic risk factors, we administered 1mg/kg of EPI, by gavage, for 2 weeks. Endpoints included weight-gain, glycemia, triglyceridemia, and systolic blood pressure. We also assessed food intake and fecal excretion. Mitochondrial function and structure related proteins were measured by Westerns.Obesity, hyperglycemia, hypertriglyceridemia, and systolic hypertension were developed after the administration of the high-fat diet for five weeks. EPI significantly decreased the rate of weight gain, glycemia and hypertriglyceridemia. The ratio between energy intake and excretion was not significantly modified by treatment. EPI restored the obesity-induced decreases in the levels of skeletal muscle and abdominal tissue sirtuins (SIRTs), peroxisome proliferator-activated receptor coactivator (PGC-1α), mitofilin, transcription factor A mitochondrial (TFAM), uncoupling protein 1 (UCP1), and deiodinase.EPI treatment yielded beneficial effects on high fat diet-induced endpoints thus may be considered as a potential agent for the treatment of obesity and its cardiometabolic associated abnormalities. Mechanism of action may be attributed to the modulation of cellular/mitochondrial function, thus improving overall metabolism., (Copyright © 2014 Elsevier B.V. All rights reserved.)

Published
2014
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