Search

Your search keyword '"Chalmers, R.J.G."' showing total 123 results
Start Over Author "Chalmers, R.J.G."
123 results on '"Chalmers, R.J.G."'

4. Secukinumab efficacy in reducing the severity and the psychosocial impact of moderate‐to‐severe psoriasis as assessed by the Simplified Psoriasis Index: results from the IPSI‐PSO study

Author

Richard, M.‐A., primary, Lacour, J.‐P., additional, Konstantinou, M.‐P., additional, Ruer‐Mulard, M., additional, Joly, P., additional, Aractingi, S., additional, Auquier, P., additional, Pelvet, B., additional, Augustin, M.L., additional, Mahé, E., additional, and Chalmers, R.J.G., additional

Published
2020
Full Text
View/download PDF

6. Traducción al español y ensayos de campo de una nueva escala destinada a la valoración global de la gravedad de la psoriasis: el índice de psoriasis simplificado (SPI)

Author

Barquero-Orias, D.E., Armellini, E., Anderson, A.J., Armellini, A., Ortega-Loayza, A.G., Helbling, I., and Chalmers, R.J.G.

Abstract

El índice de psoriasis simplificado (SPI) fue desarrollado en el Reino Unido con el fin de proveer un resumen métrico para monitorizar los cambios en la gravedad de la psoriasis (SPI-s) y su impacto social asociado (SPI-p), junto con su comportamiento y tratamiento previo (SPI-i). Existen dos versiones complementarias, una para profesionales de salud, incluidos médicos o enfermeras (proSPI) y otra para la autoevaluación de los pacientes (saSPI). Ambas versiones han demostrado tener una variabilidad al cambio, ser confiables y tener una buena correlación con los instrumentos más utilizados en los estudios clínicos, como el PASI y el DQLI. El SPI estaba ya disponible en versiones adaptadas del francés, portugués (Brasil), holandés, arábigo y tailandés.

Published
2022
Full Text
View/download PDF

11. Critical view of anaphylaxis epidemiology: Open questions and new perspectives

Author

Tanno, L.K. Bierrenbach, A.L. Simons, F.E.R. Cardona, V. Thong, B.Y.-H. Molinari, N. Calderon, M.A. Worm, M. Chang, Y.-S. Papadopoulos, N.G. Casale, T. Demoly, P. Jakob, R. Best, L. Kostanjsek, N. Chalmers, R.J.G. Linzer, J. Edwards, L. Ayme, S. Bellet, B. Franklin, R. Helbert, M. Colenbrander, A. Kashii, S. Dantas, P.E.C. Graham, C. Behrens, A. Rust, J. Cumerlato, M. Suzuki, T. Kondo, M. Takizawa, H. Kohno, N. Miura, S. Tajima, N. Ogawa, T. and on behalf the Joint Allergy Academies

Abstract

In contrast to the majority of allergic or hypersensitivity conditions, worldwide anaphylaxis epidemiological data remain sparse with low accuracy, which hampers comparable morbidity statistics. Data can differ widely depending on a number of variables. In the current document we reviewed the forms on which anaphylaxis has been defined and classified; and how it can affect epidemiological data. With regards to the methods used to capture morbidity statistics, we observed the impact of the anaphylaxis coding utilizing the World Health Organization's International Classification of Diseases. As an outcome and depending on the anaphylaxis definition, we extracted the cumulative incidence, which may not reflect the real number of new cases. The new ICD-11 anaphylaxis subsection developments and critical view of morbidity statistics data are discussed in order to reach new perspectives on anaphylaxis epidemiology. © 2018 The Author(s).

Published
2018

13. Secukinumab efficacy in reducing the severity and the psychosocial impact of moderate‐to‐severe psoriasis as assessed by the Simplified Psoriasis Index: results from the IPSI‐PSO study.

Author

Richard, M.‐A., Lacour, J.‐P., Konstantinou, M.‐P., Ruer‐Mulard, M., Joly, P., Aractingi, S., Auquier, P., Pelvet, B., Augustin, M.L., Mahé, E., and Chalmers, R.J.G.

Subjects
PSORIASIS, QUALITY of life
Abstract

Background: The utility of the Simplified Psoriasis Index (SPI), a recently developed multidomain tool for assessing psoriasis, was investigated in a study assessing response to secukinumab. Methods: In an open‐label, multicentre study involving 17 French centres, patients with moderate‐to‐severe plaque psoriasis received secukinumab 300 mg subcutaneously once weekly from baseline to W4, then every 4 weeks until W48. Dermatologist‐scored SPI psoriasis severity (proSPI‐s) was compared with Psoriasis Area and Severity Index (PASI). Patient self‐assessed severity (saSPI‐s) and psychosocial impact (SPI‐p) were compared with PASI and Dermatology Life Quality Index (DLQI), respectively. Results: We included 120 patients (69.2% male; mean age 45.9 years; mean duration of psoriasis 21.6 years). Mean baseline scores were as follows: proSPI‐s 24.9, saSPI‐s 23.5, PASI 23.1, SPI‐p 8.2 and DLQI 13.6. Severity scores achieved by 16 weeks (proSPI‐s 2.3, saSPI‐s 2.2 and PASI 2.2) were maintained to W52. Reductions in mean psychosocial impact scores were maintained to W52 (SPI‐p and DLQI, respectively, 2.1 and 1.5 at W16; 1.5 and 1.9 at W52). Conclusions: Decrease of PASI scores in response to secukinumab was closely correlated with proSPI‐s, supporting the latter's suitability for assessing response to therapy. Although the correlation between PASI and saSPI‐s was slightly weaker, patients were able to complete a valid assessment of their psoriasis independently, and thus potentially remotely. With the added benefit of psychosocial impact assessment (SPI‐p), SPI provides a valid tool enabling patients to assess their own psoriasis, remotely if necessary. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

16. The impact of psoriasis guidelines on appropriateness of referral from primary to secondary care: a randomised controlled trial.

Author

Griffith, C.E.M., Taylor, H., Collins, S.I., Hobson, J.E., Collier, P.A., Chalmers, R.J.G., Stewart, E.J.C., Dey, P., Griffith, C.E.M., Taylor, H., Collins, S.I., Hobson, J.E., Collier, P.A., Chalmers, R.J.G., Stewart, E.J.C., and Dey, P.

Abstract

Background: Most patients with psoriasis have limited disease which can be managed effectively in primary care. There is a marked variation in the frequency of referrals between practices reflecting, in part, inadequate training of general practitioners (GPs) in the management of psoriasis. Objectives: To assess the effectiveness of guidelines and training sessions on the management of psoriasis in reducing inappropriate referrals from primary care. Methods: Patients aged 18 years or over with psoriasis were eligible for the cluster-randomized, randomized controlled trial if they were referred by their GP between 9 September 2002 and 31 December 2003 to one of four hospital dermatology departments in Greater Manchester, North-West England. All GPs from 165 health centres were invited to a lecture by a local dermatologist on the diagnosis and management of psoriasis. Health centres in the intervention arm received guidelines on the management of psoriasis in primary care, developed by local dermatologists, supplemented by the offer of a practice-based nurse-led training session; those in the control arm received neither guidelines nor training sessions. Results: Eighty-two health centres were randomized to the intervention arm and 83 to the control arm. Outcome data were available for 188 of the 196 eligible patients referred during the study period. Patients in the intervention arm were significantly more likely to be appropriately referred in comparison with patients in the control arm [difference = 19·1%; odds ratio (OR) 2·47; 95% confidence interval (CI) 1·31–4·68; intracluster correlation coefficient (ICC) = 0]. Only 25 (30%) health centres in the intervention arm took up the offer of training sessions. There was no significant difference in outcome between health centres in the intervention arm that received a training session and those that did not (OR 1·28, 95% CI 0·50–3·29, ICC = 0). Conclusions: Dissemination of guidelines on the management of psoriasi

Published
2006

19. Inpatient management of psoriasis: a multicentre service review to establish national admission standards

Author

Woods, A.L., primary, Rutter, K.J., additional, Gardner, L.S., additional, Lewis, V.J., additional, Saxena, S., additional, George, S.A., additional, Chalmers, R.J.G., additional, Griffiths, C.E.M., additional, Speight, E.L., additional, Anstey, A.V., additional, Ronda, L., additional, McGibbon, D., additional, Barker, J.W.N., additional, and Smith, C.H., additional

Published
2007
Full Text
View/download PDF

20. A classification of psoriasis vulgaris according to phenotype

Author

Griffiths, C.E.M., primary, Christophers, E., additional, Barker, J.N.W.N., additional, Chalmers, R.J.G., additional, Chimenti, S., additional, Krueger, G.G., additional, Leonardi, C., additional, Menter, A., additional, Ortonne, J.-P., additional, and Fry, L., additional

Published
2007
Full Text
View/download PDF

35. Reply

Author

Boffa, M. J., primary, Chalmers, R.J.G., additional, Haboubi, N.Y., additional, Shomaf, M., additional, and Mrrtchell, D.M., additional

Published
1996
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results