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The degradation of an antibiotic drug was investigated by low-cost nanocomposite material. The visible light responsive non-metal activated carbon doped TiO2 nanocomposite photocatalyst with wide band gap energy was synthesized via the co-precipitation method with an equal mass ratio of activated carbon and TiO2. Under optimal conditions, the photocatalytic experiment was carried out in a batch reactor in the presence of irradiation of 15W UV light. A significant effect of carbon caused a notable reduction in the optical band gap of doped with TiO2. The composite showed the maximum removal of 87.6% tetracycline drug in 45 min. The optimal catalyst dose and drug concentration were found to be 1.25 g and 100 mg/L, respectively, but the optimal reaction time, 45 min, and pH = 6.5 are very significant in the presence of UV light. The kinetic experimental data showed the best fitting for both pseudo-first-order (ka = 21.83 min−1) and pseudo-second-order (0.23 g/g min) models with a high accuracy based on R2 values. Freundlich model showed a maximum adsorption capacity (qm) of 94.87 (mg/g) for tetracycline drug removal on the heterogeneous surface with higher accuracy (R2 = 0.999) than the Langmuir model. Adsorption followed by degradation was shown at optimized pH, while intraparticle diffusion phenomena act as the rate-limiting step. Moreover, a proposed drug degradation mechanism based on the formation of hydroxyl free radicals is suggested, and LC–MS analysis identified fourteen intermediate products during drug degradation. At the same time, the antibacterial activity test showed that the generated degradation products were less toxic compared to the tetracycline molecule. [ABSTRACT FROM AUTHOR]

Context: Selective obturator nerve block (ONB) limits obturator reflex, adductor contraction, and leg jerking in transurethral resection of bladder tumour (TURBT), which ultimately prevents complications such as bleeding, bladder perforation, or incomplete tumor resection. The present study aims to compare the effectiveness of two different techniques of obturator nerve block during TURBT. Methods: A prospective, observational study was conducted in the Department of Anaesthesia, Analgesia, Palliative and Intensive Care Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh, between September 2018 and August 2019 to evaluate the effectiveness of ultrasound guided ONB versus cystoscopy guided ONB in TURBT operation. A total of 60 selected patients were randomly allocated into two groups: ultrasound guided ONB (group A) and cystoscopy guided ONB (group B) i.e. 30 in each group. Then onset of anesthesia (nerve block), tumour removal and patient outcome were assessed at different point during and after surgery. Results: Mean age of the patients was 54.7±8.53 years. In total, 34(57%) cases were male and 26(43%) were female. Male to female ratio was 1.3:1. In group A, 19(63.3%) patients had ASA II status and 11(36.7%) had ASA III status, while in group B, the numbers were 18(60%) and 12(40%) respectively. There was no significant difference in demographics and ASA status between two groups (P>0.05). Average onset of obturator nerve block was faster in group A (8.17±1.4 min) than group B (11.3±2.68 min), (P<0.001). Total resectability of tumours were achieved in 28(93.3%) in group A and 23(76.6%) in group B during operation (P<0.001), while 2(22.22%) and 7(77.77%) tumours had incomplete removal respectively (P<0.05). Among complications, adductor jerks were evident in 2(6.7%) and 7(23.3%), bladder perforation in 1(3.3%) and 4(13.3%), and bleeding in 1(3.3%) and 3(10.0%) cases in group A and group B respectively. The differences were statistically significant ((P<0.05). Conclusion: Although both techniques are safe and easy to perform, ultrasound guided ONB results in faster onset of block and better resectability of tumour with less complication over cystoscopy guided ONB. [ABSTRACT FROM AUTHOR]

Studies on the response of weed control methods on the growth and yield of sesame, Sesamum indicum L was conducted at the Agronomy field of Sher-e-Bangla Agricultural University, Dhaka, Bangladesh. The highest number of weed species (11.33 m-2) and total number of weeds (175.67 m-2) were found in pre-emergence herbicide, Sunup 480 SL (Glyphoset) @ 3.7 l/ha spraying at land preparation (W4). The highest dry weight of weed (215.32 g m-2) was observed in no weeding (W1) and the lowest dry weed biomass (111.43 g m-2) was observed in one hand weeding at 20 days after sowing (DAS) (W2). The highest plant height (139.89 cm) was observed in pre-emergence herbicide management (W4) and the maximum number of leaves per plant (43.02) was observed from two hand weedings at 20 and 40 DAS (W3). The highest number of capsules per plant(70.88), seeds per capsule(72.00), seed yield (1.51 t ha-1) and harvest index (16.25%) were obtained from two hand weedings at 20 and 40 DAS (W3). The highest 1000 seeds weight (3.30 g) was observed in two hand weedings at 20 and 40 DAS (W3). The highest biological yield (9.33 t ha-1) and stover yield (7.81 t ha-1) were also obtained from BARI til-3 with two hand weedings at 20 and 40 DAS (W3). Economic analysis revealed that two hand weedings at 20 and 40 DAS for weed control recorded maximum gross margin (TK 79195 ha-1) with benefit-cost ratio of 2.28. [ABSTRACT FROM AUTHOR]

Performances of tissue cultured (TC) plantlets of BARI Kola-3 and BARI Kola-4 were evaluated against transplanting of conventional (CON) sucker at hill valleys during July 2011 to December 2014. The plantlets were produced at Biotech Lab, BARI Gazipur and validation trial was conducted at Ramgarh, Khagrachari hill district during March-April and September-October planting seasons (2011-14). Murashige and Skoog (MS) basal medium supplemented @ 3 mg 1-l and 5 mg l-1 BAP showed the best performance for multiple shoot production in BARI Kola-3 and BARI Kola-4, respectively. Both the varieties produced well developed roots in ½MS medium supplemented @ 0.5 mg 1-l IBA. Among the plantlets 98.5% plantlets were survived when hardened 7 days under polyethylene tunnel after 5 days hardening at room temperature but 100% plantlets died when transplanted plantlets were kept in open conditions at the nursery. 45 day - old healthy plantlets were planted at hill valleys in September-October and April-May planting seasons. BARI Kola-3 produced the highest 45.67 and 44.05 t ha-1 bunch yield at April- May and September-October planting, respectively. The highest 55.89 t ha-1 bunch yield was recorded from TC BARI Kola-4 in March-April planting followed by 49.67 t ha-1 in September-October Planting. TC BARI Kola-3 and BARI Kola-4 produced 3.68 and 12.52% higher yields in March-April planting, respectively than September-October planting. In case of planting materials, TC BARI Kola-3 and TC BARI Kola-4 produced 23.43 and 20.33% higher yield over CON suckered plant in March-April planting. On the other hand, TC BARI Kola-3 and TC BARI Kola-4 also produced 12.34 and 9.35% higher yield than CON Suckered plant in September-October planting. Similarly, TC BARI Kola-4 produced 28.33% higher yield than CON suckered BARI Kola-4 in March-April planting. In every case, TC plants showed better performances than the CON suckered plant. [ABSTRACT FROM AUTHOR]

Abstract Background Historically, the Chittagong Hill Tracts (CHT) of Bangladesh was considered hyperendemic for malaria. To better understand the contemporary malaria epidemiology and to develop new and innovative control strategies, comprehensive epidemiologic studies are ongoing in two endemic unions of Bandarban district of CHT. Within these studies entomological surveillance has been undertaken to study the role of the existing anopheline species involved in the malaria transmission cycle throughout the year. Methods CDC miniature light traps were deployed to collect anopheline mosquitoes from the sleeping room of the selected houses each month in a single union (Kuhalong). Molecular identification was carried out for available Anopheles species complexes. Circumsporozoite proteins (CSP) for Plasmodium falciparum, Plasmodium vivax-210 (Pv-210) and Plasmodium vivax-247(Pv-247) were detected by Enzyme-linked immunosorbent assay (ELISA) from the female anopheline mosquitoes. To confirm CSP-ELISA results, polymerase chain reaction (PCR) was also performed. Results A total of 2,837 anopheline mosquitoes, of which 2,576 were female, belonging to 20 species were collected from July 2009 -June 2010. Anopheles jeyporiensis was the most abundant species (18.9%), followed by An. vagus (16.8%) and An. kochi (14.4%). ELISA was performed on 2,467 female mosquitoes of 19 species. 15 (0.6%) female anophelines belonging to eight species were found to be positive for Plasmodium infection by CSP-ELISA. Of those, 11 (0.4%) mosquitoes were positive for P. falciparum and four (0.2%) for Pv-210. No mosquito was found positive for Pv-247. An. maculatus (2.1%, 2/97) had the highest infection rate followed by An. umbrosus (1.7%, 2/115) and An. barbirostris (1.1%, 2/186). Other infected species were An. nigerrimus, An. nivipes, An. jeyporiensis, An. kochi, and An. vagus. Out of 11 P. falciparum CSP positive samples, seven turned out to be positive by PCR. None of the samples positive for Pv-210 was positive by PCR. In terms of abundance and incrimination, the results suggest that An. maculatus, An. jeyporiensis and An. nivipes play important roles in malaria transmission in Kuhalong. Conclusion The findings of this study suggest that even in the presence of an insecticide impregnated bed-net intervention, a number of Anopheles species still play a role in the transmission of malaria. Further investigations are required to reveal the detailed biology and insecticide resistance patterns of the vector mosquito species in endemic areas in Bangladesh in order to assist with the planning and implementation of improved malaria control strategies.

Aim: Accurate and appropriate cognitive screening can significantly enhance early psychosis care, yet no screening tools have been validated for the early psychosis population and little is known about current screening practices, experiences, or factors that may influence implementation. CogScreen is a hybrid type 1 study aiming to validate two promising screening tools with young people with first episode psychosis (primary aim) and to understand the context for implementing cognitive screening in early psychosis settings (secondary aim). This protocol outlines the implementation study, which aims to explore the current practices, acceptability, feasibility and determinants of cognitive screening in early psychosis settings from the perspective of key stakeholders., Methods: Young people with first episode psychosis (n = 350), caregivers (minimum n = 10) and service providers (minimum n = 12) will be recruited from primary and specialist early psychosis services in Melbourne, Adelaide and Sydney, Australia. Two implementation science frameworks will inform data collection and analysis: the Theoretical Framework of Acceptability and the Consolidated Framework for Implementation Research. A mixed-methods design will be employed to collect and analyse data from questionnaires with young people, interviews with all stakeholder groups, and administrative processes. Quantitative data will be analysed using descriptive statistics. Qualitative data will be analysed through content analysis using deductive and inductive coding., Results and Discussion: This protocol paper presents the rationale and methods for the CogScreen implementation study., Conclusion: Together with accuracy findings, results from the implementation study will provide insights about the practices, experiences, enablers and barriers to cognitive screening in early psychosis services., (© 2025 The Author(s). Early Intervention in Psychiatry published by John Wiley & Sons Australia, Ltd.)

Aim: Cognitive impairments are a core feature of first-episode psychosis (FEP) and one of the strongest predictors of long-term psychosocial functioning. Cognition should be assessed and treated as part of routine clinical care for FEP. Cognitive screening offers the opportunity to rapidly identify and triage those in most need of cognitive support. However, there are currently no validated screening measures for young people with FEP. CogScreen is a hybrid effectiveness-implementation study which aims to evaluate the classification accuracy (relative to a neuropsychological assessment as a reference standard), test-retest reliability and acceptability of two cognitive screening tools in young people with FEP., Methods: Participants will be 350 young people (aged 12-25) attending primary and specialist FEP treatment centres in three large metropolitan cities (Adelaide, Sydney, and Melbourne) in Australia. All participants will complete a cross-sectional assessment over two sessions including two cognitive screening tools (Screen for Cognitive Impairment in Psychiatry and Montreal Cognitive Assessment), a comprehensive neuropsychological assessment battery, psychiatric and neurodevelopmental assessments, and other supplementary clinical measures. To determine the test-retest reliability of the cognitive screening tools, a subset of 120 participants will repeat the screening measures two weeks later., Results: The protocol, rationale, and hypotheses for CogScreen are presented., Conclusions: CogScreen will provide empirical evidence for the validity and reliability of two cognitive screening tools when compared to a comprehensive neuropsychological assessment. The screening measures may later be incorporated into clinical practice to assist with rapid identification and treatment of cognitive deficits commonly experienced by young people with FEP., (© 2024 The Author(s). Early Intervention in Psychiatry published by John Wiley & Sons Australia, Ltd.)

The rising soil-groundwater quality issues due to pharmaceuticals and personal care products (PPCPs) contamination have spurred significant concern. To understand the sorption characteristics of metformin (MTN) and erythromycin (ETM) in sandy and sandy loam soils with varying organic matter and particle composition, sorption kinetics (single and competitive), isotherms, and thermodynamics were studied. The effects of pH and soil moisture content (SMC) were also investigated at environmentally relevant concentrations. The equilibrium time of MTN and ETM sorption by the three soils in a competitive solute system was about 4 h, and the sorption process was in line with a pseudo-second-order model. The rate-determining step in the process involved both intraparticle diffusion and liquid film diffusion mechanisms for the two PPCPs. The highest pollutant uptake occurred in soils with higher organic matter, driven by enhanced H-bonding, electrostatic interactions, and π-π and n-π interactions facilitated by the organic matter. The equilibrium data in the three soils was well described by the Freundlich model and confirmed favourable adsorption (1/n f  = 1.01-1.90). The sorption coefficient (K d ) on the three soils ranged from 2.1 to 332 L/kg for MTN and from 6.25 to 845 L/kg for ETM. The adsorption process was feasible at 293 K and 303 K (ΔG° = - 0.16 to -10.24 kJ/mol), physical and exothermic in nature (ΔH° = -75.21 to -10.30 kJ/mol) for both the contaminants. Observed alterations in Q e with pH confirmed the participation of electrostatic interactions. A low SMC favoured both MTN and ETM sorption onto the sandy soil. Overall, ETM exhibits higher expected sorption, whereas MTN has a greater tendency for migration in the soils and is thus liable to contaminate the groundwater. The study accentuates novel insights into the transport and fate of MTN and ETM in soil-groundwater systems at environmentally relevant concentrations., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Inc. All rights reserved.)

The presence of pharmaceutical and personal care products (PPCPs) in the environment poses a significant threat to environmental resources, given their potential risks to ecosystems and human health, even in trace amounts. While mathematical modelling offers a comprehensive approach to understanding the fate and transport of PPCPs in the environment, such studies have garnered less attention compared to field and laboratory investigations. This review examines the current state of modelling PPCPs, focusing on their sources, fate and transport mechanisms, and interactions within the whole ecosystem. Emphasis is placed on critically evaluating and discussing the underlying principles, ongoing advancements, and applications of diverse multimedia models across geographically distinct regions. Furthermore, the review underscores the imperative of ensuring data quality, strategically planning monitoring initiatives, and leveraging cutting-edge modelling techniques in the quest for a more holistic understanding of PPCP dynamics. It also ventures into prospective developments, particularly the integration of Artificial Intelligence (AI) and Machine Learning (ML) methodologies, to enhance the precision and predictive capabilities of PPCP models. In addition, the broader implications of PPCP modelling on sustainability development goals (SDG) and the One Health approach are also discussed. GIS-based modelling offers a cost-effective approach for incorporating time-variable parameters, enabling a spatially explicit analysis of contaminant fate. Swin-Transformer model enhanced with Normalization Attention Modules demonstrated strong groundwater level estimation with an R 2 of 82 %. Meanwhile, integrating Interferometric Synthetic Aperture Radar (InSAR) time-series with gravity recovery and climate experiment (GRACE) data has been pivotal for assessing water-mass changes in the Indo-Gangetic basin, enhancing PPCP fate and transport modelling accuracy, though ongoing refinement is necessary for a comprehensive understanding of PPCP dynamics. The review aims to establish a framework for the future development of a comprehensive PPCP modelling approach, aiding researchers and policymakers in effectively managing water resources impacted by increasing PPCP levels., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier B.V.)

Sarcomas, a diverse group of malignant tumors originating from connective tissues, present substantial diagnostic challenges due to their histological heterogeneity. Traditional diagnostic methods include histomorphology along with immunohistochemistry is necessary for primary evaluation. Fluorescence in situ hybridization (FISH) is a supplementary tool that helps with additional findings. However it is very difficult sometimes to accurately classify sarcoma subtypes despite all these tools. Recent advancements in DNA methylation profiling have emerged as a promising approach to enhance the precision of sarcoma diagnosis. This paper delves into the role of DNA methylation classifiers in diagnosing sarcomas, emphasizing their potential to improve diagnostic accuracy, inform treatment decisions, and ultimately enhance patient outcomes., Competing Interests: Declaration of Competing Interest There are no declaration of interest from the authors., (Copyright © 2024 Elsevier GmbH. All rights reserved.)

The over-pumping of freshwater makes shoreline aquifers susceptible to seawater intrusion. Most studies on aquifer homogeneity that are used to form management guidelines focus on salinization sensitivity. However, under certain extraction conditions, the geographic structure can be quite diverse, with low-permeability obstacles and preferred flow routes that affect circulation and saline transport mechanisms. Here, we used a laboratory-scale glass box apparatus of dimension 100 × 50 × 10 cm 3 to study intrusion in stratified layers under the influence of an inclined ocean-aquifer boundary with a mixed barrier as a remediation technique. The T L \H ratio ranged from 0.2 to 12.84 for all stratification conditions and remediation installed. There was a 40-48 % decrease in the extent of toe length after installation. With a mixed barrier installed, the height of the intrusion was reduced, resulting in an increase in the T L \H and a decrease in the potential for toe length. The intrusion was delayed by 86.67 % in parallel stratification and 28.22 % in perpendicular stratification after comparing the time frame for base case and the mixed barrier installed condition. A parabolic profile of intrusion was observed in the low-permeability layer, while a convex-outward profile was observed in the higher-permeability layers. Similar results are obtained after conducting the sensitivity analysis. The intrusion follows an increasing pattern of ratio with increasing interaction gap opening in parallel stratification, while for perpendicular stratification, with gap opening from 10 cm to 30 cm, there was a decreasing trend followed by an increasing trend, indicating an increase in magnitude with a similar pattern of intrusion. The results of this investigation shed light on the mixed barrier's suitability for use in realistically diverse coastal aquifers. Future research could explore the utilization of different combinations of new barriers, such as under-surface barriers, which work well for stratified layers, and already established barrier systems, to further improve the efficiency of mixed barriers., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier B.V.)

The study aimed to assess and characterize microplastics (MPs) in muscles, guts, and gills of six commercially important marine fish from the Bay of Bengal. FTIR was utilized to identify MP's polymer compositions. A total 7085 MPs identified, where tuna exhibited the highest count and Bombay duck had the lowest. MPs abundance (MPs/g) was ranged from 1.56 ± 0.39 to 7.16 ± 1.36 in muscles, 1.91 ± 0.32 to 4.46 ± 0.75 in guts, and 2.36 ± 0.24 to 6.53 ± 1.58 in gills. The predominant MPs were 1-5 mm size (33.33-62.78 %), white/transparent color (18.45-54.63 %), filament shapes (75.00-94.71), and fiber types (73.21-94.71 %). FTIR revealed MPs 58.89 % polyethylene, 21.67 % polypropylene, 17.22 % polyester, and 2.22 % non-plastic compositions. Cluster analysis grouped two species with 50 % similarity, while PCA indicated significant variations among principal components (14-69.4 %) highlighting the dominance of fiber, particles, and 0.5-1.0 mm MPs in the fish tissues. The prevalence of MPs in seafood underscores measures to safeguard both the marine ecosystem and human health., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Zero-valent iron (ZVI) applied to the remediation of contaminated groundwater (GW) in situ, especially using engineered permeable reactive barriers (PRBs), has been proven to be an effective reactive material. However, many of ZVI brands do not represent tailored reagents specifically regarding destroying pollutants in GW. Thus, their reactivity towards certain contaminants in GW may vary significantly in a wide range even with different production batches of the same ZVI brand. This issue has rarely been known and consequently not addressed to a higher extend so far. Therefore, this study implemented extensive, long-term column experiments followed by short-term batch experiments for chlorinated volatile organic compounds (cVOCs) degradation for developing a semi-empirical test methodology to thoroughly resolve this pivotal issue by achieving an improved quality assurance guidance regarding proper field-scale emplacement of different ZVI brands and their production batches. The results showed that during column experiments perchloroethylene (PCE) led to a significant degradation up to a certain period but sulfate-reducing microorganisms enhanced the dehalogenation and led approximately to 100 % PCE removal. However, the efficacy varied for different ZVI brands, i.e., Gotthart Maier (GM) and Sponge Iron (Responge®). Furthermore, it could be shown that it might even vary among different production batches of the same ZVI brand. It was also observed that evolution of sulfate-reducing microorganisms may improve the efficacy of PCE degradation vastly that occur at different intensities with different ZVI brands and their respective production batches over time. Further, comparing comprehensive long-term column (k obs  = 0.0488 1/h) and short-term batch experiments (k obs = 0.07794 1/h) as well as refined kinetic analyses (k obs  = 0.0424 1/h) clearly prove that an appropriate guidance protocol for successful full-scale in situ remediation is required for properly select the right ZVI brand and production batch before it is loaded to a PRB in the field., Competing Interests: Declaration of competing interest The authors declared that they have no known competing financial interests or personal relationships, which seem to affect the work reported in this article. We declare that we have no human participants, human data, or human issues. We do not have any individual person's data in any form. The authors declare no competing interests., (Copyright © 2024. Published by Elsevier Ltd.)

The presence of heavy metal contaminants in fish and shellfish in aquatic environments poses a risk to human health due to trophic transfer. This study determined the levels of various trace elements (Fe, As, Cr, Zn, Cu, Ni, Pb, and Cd) in the muscles, gills, and liver of hilsa (Tenualosa ilisha) and prawn (Macrobrachium rosenbergii) samples obtained from the Tetulia River, Bangladesh. The results showed that the level of trace elements in different body parts differed significantly (P < 0.05) between species, displayed below recommended threshold levels. The cumulative low to higher hierarchic concentration of the trace elements was as follows: Fe > Zn > Cu > Cr > Ni > Pb > As > Cd. Hilsa had significantly (P < 0.05) higher bioaccumulated trace elements compared to prawn. With the exception of Ni and Cd, the estimated daily intakes (EDI) for both adults and children were below the recommended daily allowance (RDA), which exhibits that other trace elements do not cause harm to human health. Furthermore, the hazard index (HI) and total hazard quotient (THQ) were also found to be within acceptable limits, taking into account the higher vulnerability of children to toxicity compared to adults. Notably, the HI suggested that children were approximately four times more susceptible to both carcinogenic and non-carcinogenic effects compared to adults. Ultimately, the levels of carcinogenic risk were deemed acceptable, despite the estimated values suggesting susceptibility to adverse effects in both adults and children. This study concluded that fish and shellfish may not pose a health risk to consumers, highlighting the importance of further monitoring of trace elements in the catchment area., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

This study investigates the fate and transport dynamics of metformin (MTN) and erythromycin (ETM), both classified as pharmaceutical and personal care products (PPCPs), in a saturated sandy soil column using temporal moment analysis (TMA). The key flow and transport parameters, including Darcy velocity, longitudinal dispersivity, adsorption, and degradation coefficients, were analyzed. The results reveal that MTN, a highly mobile contaminant, is eliminated from the column in approximately 40 days, while ETM shows significant adsorption due to its hydrophobic and adsorptive nature. Darcy velocity significantly affects PPCP transport; a one-order magnitude change alters contaminant mass recovery at the column outlet by 88% for MTN and 39-fold for ETM. Longitudinal dispersivity has minimal impact on the transport of PPCPs. However adsorption primarily governs the fate of PPCPs with high adsorption coefficients (K d ), and degradation rates control the fate of low-sorbing PPCPs. A one-order magnitude change in K d results in a 55% change in the zeroth temporal moment (ZTM) of MTN and a 30-fold change in the case of ETM. Additionally, a one-order magnitude change in the degradation coefficient leads to a 60% variation in MTN's ZTM and a 5% variation in ETM's ZTM. Thus, TMA is a valuable tool for understanding PPCP dynamics in subsurface environments, providing critical insights for managing their increasing concentrations., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

The innovative approach of harnessing abundant solar energy to facilitate water purification holds great potential for addressing a diverse range of water-related challenges. Utilizing the same method of photothermal desalination is highly promising, sustainable, and cost effective. However, in photothermal desalination, generally, steam is generated at the liquid-air interface. Despite its immense potential, this results in a lower evaporation rate and is prone to salt fouling. Therefore, to address two main challenges, (1) fouling and (2) maximum interfacial temperature (100 °C), here, we report total contactless photothermal desalination by a translucent thin film coating of Crystalline Nanocellulose (CNC). In contactless photothermal desalination, the active photothermal layer remains in no physical contact with the saline water; thus, automatic antifouling and a temperature above the boiling point of water can be achieved for water purification. In this report, we have sustainably extracted CNC from waste sawdust by a sonochemical extraction method using minimal chemicals. Additionally, the sonoextraction method through cavitation helps in the desulfation of CNC. These thermally stable and highly crystalline CNCs are used in making active translucent photothermal active layers for photothermal desalination. CNCs were well characterized by both microscopic and spectroscopic techniques. In the photothermal desalination, the results show an augmented evaporation rate of ∼3.30 kg/m 2 ·h and virtually infinite recyclability for longer usability. Moreover, the integrated setup reported here comprises an independent module with a highly flexible design that mimics the greenhouse effect for a high solar-to-steam output.

The deteriorating environmental conditions due to increasing emerging recalcitrant pollutants raised a severe concern for its remediation. In this study, we have reported antibiotic degradation using free and immobilized HRP. The functionalized cellulose support was utilized for efficient immobilization of HRP. Approximately 13.32 ± 0.52 mg/g enzyme loading was achieved with >99% immobilization efficiency. The higher percentage of immobilization is attributed to the higher surface area and carboxylic groups on the support. The kinetic parameter of immobilized enzymes was K m  = 2.99 mM/L for CNF-CA@HRP, which is 3.5-fold more than the Michaelis constant (K m  = 0.84794 mM/L) for free HRP. The V max of CNF-CA@HRP bioconjugate was 2.36072 mM/min and 0.558254 mM/min for free HRP. The highest degradation of 50, 54.3, and 97% were achieved with enzymatic, sonolysis, and sono-enzymatic with CNF-CA@HRP bioconjugate, respectively. The reaction kinetics analysis revealed that applying ultrasound with an enzymatic process could enhance the reaction rate by 2.7-8.4 times compared to the conventional enzymatic process. Also, ultrasound changes the reaction from diffusion mode to the kinetic regime with a more oriented and fruitful collision between the molecules. The thermodynamic analysis suggested that the system was endothermic and spontaneous. While LC-MS analysis and OTC's degradation mechanism suggest, it mainly involves hydroxylation, secondary alcohol oxidation, dehydration, and decarbonylation. Additionally, the toxicity test confirmed that the sono-enzymatic process helps toward achieving complete mineralization. Further, the reusability of bioconjugate shows that immobilized enzymes are more efficient than the free enzyme., (Copyright © 2023 Elsevier Ltd. All rights reserved.)

This study aims to investigate factors influencing the adoption of clean energy among households in Bangladesh, using Blinder-Oaxaca decomposition and extended probit regression model with data from the 2019 Bangladesh multiple indicator cluster survey. Small households, primarily Muslim and urban dwellers, who speak the Bengali language and are Internet and mobile users, were likelier to adopt cleaner fuels than their counterparts. On the contrary, households residing in the Barisal, Khulna, Rajshahi, and Rangpur divisions, belonging to poor and middle-class households, with household heads aged 15-64 and without formal education, were less likely to adopt cleaner fuels than their counterparts. The concentration curve revealed socioeconomic inequality in the adoption of clean energy, particularly favouring richer households in urban and rural areas. Further analysis using the Blinder-Oaxaca decomposition showed that urban residents showed a higher probability of adopting clean energy, with a significant difference of 0.508 compared to rural areas. Regarding the endowment effect, poor wealth quintile contributed the most, followed by the ownership of rented dwellings and the middle wealth quintile. The Bengali differential effect made the largest contribution to this aspect of the disparity, followed by the exposure of the Internet and the influence of the Dhaka and Chattogram divisions. The detailed analysis provides valuable insights for policymakers and practitioners on the issue of disparities in the adoption of clean energy between urban and rural areas in Bangladesh., (© 2024. The Author(s).)

We conducted a service evaluation of the medical support worker (MSW) role at Oxford University Hospitals NHS Foundation Trust following the Coronavirus 2019 (COVID-19) pandemic. The aim was to explore the roles of MSWs, their contributions to the NHS, factors influencing their career choices, and the goals of the MSW position, to inform quality improvement in relation to their integration into the Trust. The perspectives of MSWs, their supervisors and recruiters were analysed through nine semi-structured interviews and two focus group discussions involving 18 participants. Results were categorised into micro-, meso-, and macro-levels of the health system. At the micro-level, MSWs were recognised as a diverse group of highly qualified international medical graduates (IMGs) who had a crucial role during the pandemic. At the meso-level, participants emphasised the importance of a comprehensive induction by the hospital, to clarify responsibilities and familiarise MSWs with the health system. At the macro-level, the role facilitated MSW integration within the NHS, with the aim of practising as doctors. The importance of comprehensive hospital induction, with role clarity for both MSWs and their teams, supportive supervision and assistance with applying for registration with the General Medical Council, were highlighted as key quality improvement areas., (Copyright © 2023. Published by Elsevier Ltd.)

Self-supply water has been acknowledged as a viable alternative to meeting the water needs of inhabitants. This study was designed to determine the main issues that influence self-supply water coverage in five (5) communities in the Kumasi Metropolis. The research employed a well-structured questionnaires and a total of 369 households were surveyed. The Statistical Package for Social Sciences (SPSS) version 26 and Microsoft Excel (2016) tools were used to analyse the data. The outcomes of the research show that a greater number of the respondents (77 %) did not have connections to the Ghana Water Company Limited (GWCL) distribution system. Approximately, 69 % of respondents had access to alternative water sources with mechanized boreholes forming the majority (32 %). However, a greater number of the respondents (64 %) did not disinfect their water to make it potable. The most favourable drinking water source for a greater number of the residents (51 %) was sachet water. The study showed there was a significant association between respondents' type or source of water with religion (p < 0.000), household size (p < 0.000), duration of stay (p = 0.026) and number of dependents (p = 0.006). However, there was no association between type or source of water with educational level (p = 0.130), occupation (p = 0.310), income level (p = 0.139) and type of home (p = 0.102). This study revealed that self-supply is contributing to the water needs of some residents in Kumasi and could contribute to the country's accomplishment of SDG 6.1 if residents ensure that it is safely managed. To broaden the scope of the study and the impact of self-supply groundwater, additional studies should be conducted in other communities, as well as the extent of other beneficiaries who have access to self-supply facilities other than the owners., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2023 The Authors.)

Ensuring adherence to antimalarial treatment is crucial for achieving a radical cure and elimination of malaria, especially in hard-to-reach areas. We conducted this study to assess the current scenario of drug adherence in four endemic sub-districts of Bangladesh. Among 110 enrolled participants, 70% were mono-infected with Plasmodium falciparum and the remaining 30% with P. vivax . The overall treatment adherence frequency was 92.7% (95% CI: 83.0-96.3%). A total of eight participants were found to be nonadherent to treatment and all of them were from Bandarban. Level of nonadherence was equally observed in two age groups: 11-17 and 18+ years. However, male participants ( n = 6) were found to be more nonadherent than females ( n = 2). Among 7.3% with nonadherence to treatment, a single participant with P. falciparum mono-infection refused to take medication and became nonadherent. Remaining participants stated that they were feeling well and going to work, thus leaving treatment course uncompleted. Although overall compliance with malaria medication seems good, a gradual increase in noncompliance to P. vivax malaria treatment suggests that the National Malaria Elimination Program must be enhanced and monitored to fulfil the projected malaria elimination goal before 2030 from Bangladesh.

The influence of low permeability porous media (LPPM) on contaminant transport dynamics in saturated porous systems was investigated using numerical simulations and temporal moments of contaminant concentrations. Two-dimensional flow and contaminant transport simulations were conducted, considering various parameters such as longitudinal dispersivity (ranging from 15 to 60 m), the ratio of transverse to longitudinal dispersivity (ranging from 0.05 to 0.2), retardation factor (ranging from 1 to 4), and hydraulic gradient (ranging from 0.005 to 0.02) for both homogeneous and heterogeneous porous systems. The findings revealed significant differences in the transport behavior of conservative and highly reactive contaminants between the porous systems without and with the LPPM region. The center of mass of contaminant plume and peak concentration zone were observed inside the LPPM region for the heterogeneous porous system, especially during the source off-loading period. Furthermore, asymmetric distributions of the zeroth temporal moment (ZTM), mean residence time (MRT), and variance of the breakthrough curve (BTC) were observed along the longitudinal distance within the LPPM region for heterogeneous porous system, highlighting the impact of heterogeneity on contaminant plume evolution dynamics. The moment analysis results provided insights into the influence of LPPM region on time-averaged contaminant transport dynamics in adjacent porous systems. These findings can help risk managers understand the complex fate and transport dynamics in heterogeneous porous systems. Future studies could explore the modelling of multispecies contaminants in heterogeneous saturated porous systems subjected to fluctuating water table., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

Background: This research aimed to examine the factors at both the individual and community levels that are linked to discrimination experienced by women aged 15-49 in Bangladesh., Methods: The relevant data was taken from the 2019 Multiple Indicator Cluster Survey in Bangladesh. The risk factors for discrimination against women in Bangladesh were determined using multilevel logistic regression models., Results: The overall prevalence of discrimination against women was found to be 10.4% (95% CI: 10.1-10.6). Based on the final model (Model 1V), at the individual level higher odds of discrimination were observed among women from poor (AOR:1.21,95%CI: 1.12-1.32) and middle income households (AOR:1.12, 95%CI:1.02-1.22) compared to those from rich households etc. Women who have never used ICT were 1.27 times (AOR = 1.27, 95% CI = 1.07-1.51) higher odds of discrimination when compared with women who were ICT exposed. Respondents who married before 18 years 10% more likely to (AOR = 1.10, 95% CI:1.02-1.19) discriminated than women married aged 18 years old or above. Women from urban communities were 15% less likely to experience discrimination than their rural counterparts. In comparison to the Sylhet Division, women in the Barisal, Chattogram, Dhaka, Khulna Mymensingh, Rajshahi, and Rangpur Divisions were respectively 3.02, 1.84, 1.68, 2.06, 4.97, 4.06, and 1.74 times more likely to experience discrimination., Conclusion: Findings revealed that various individual-level factors such as wealth index, CEB, ICT exposure, marital status, functional difficulty, age, women's happiness, magazine and radio exposure, age at marriage, current contraceptive use, polygamy, husband beating, place of attack, and household head age were found to have a significant association with women discrimination. Community-level factors such as residence and division were also found to have a notable impact on discrimination. Policymakers should incorporate substantial components targeting both individual and community levels into intervention programs with the goal of raising awareness about women's discrimination., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2023 Haq et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Owing to a huge amount of industrial organic waste generation in the recent past, concerned industries are facing immense challenges for in situ treatment and disposal of such wastes. Therefore, in this study, the efficacy assessment of in situ windrow composting of pressmud (PM) produced by sugar industry has been investigated. Samples were grabbed and mixed from windrows having composting days of 15 (PM15), 30 (PM30), and 45 (PM45) and were collected along with a compost sample from the 60th day (PMC) windrow. An investigation of physico-chemical parameters including pH, electrical conductivity, moisture content, volatile solids (VS), ash content, biochemical oxygen demand, chemical oxygen demand, total nitrogen, and C/N ratio was performed for raw PM and other aforementioned samples. Moreover, speciation of heavy metals (Cu, Cr, Ni, Pb, Cd, and Zn), X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopic analyses were performed for PM and PMC to evaluate the heavy metal toxicity and mineralogical and chemical changes. The analysis showed 20.33% reduction in VS content and 53.65% increase in TN content after 60 days of in situ windrow composting. The pH and EC values of PMC were found to be lesser than that of upper values recommended for agricultural purposes. Furthermore, the speciation analysis showed significant reduction in bioavailability of heavy metals. The XRD and FTIR results were confirmatory for transformation of heavy metals into relatively stable forms. The study recommends the windrow composting practice as effective bioconversion technique that stabilizes organic content, enhances humification, and diminishes heavy metal bioavailability for PM and similar other sludges., (© 2023. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)

The study on the fate and transport of Pharmaceuticals and Personal Care Products, PPCPs (FTP) in the environment, has received particular attention for over two decades. The PPCPs threaten ecology and human health even at low concentrations due to their synergistic effects and long-range transport. The research aims to provide an inclusive map of the scientific background of FTP research over the last 25 years, from 1996 to 2020, to identify the main characteristics, evolution, salient research themes, trends, and research hotspots in the field of interest. Bibliometric networks were synthesized and analyzed for 577 journal articles extracted from the Scopus database. Consequently, seven major themes of FTP research were identified as follows: (i) PPCPs category; (ii) hazardous effects; (iii) occurrence of PPCPs; (iv) PPCPs in organisms; (v) remediation; (vi) FTP-governing processes; and (vii) assessment in the environment. The themes gave an in-depth picture of the sources of PPCPs and their transport and fate processes in the environment, which originated from sewage treatment plants and transported further to sediment/soils/groundwater/oceans that act as the PPCPs' major sink. The article provided a rigorous analysis of the research landscape in the FTP study conducted during the specified years. The prominent research themes, content analysis, and research hotspots identified in the study may serve as the basis of real-time guidance to lead future research areas and a prior review for policymakers and practitioners., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

Waste management and mitigation is the primary necessity across the globe. The daily use of plastic materials in different forms emergence the plastic pollutions, and it has been significantly increased during the COVID-19 pandemic. Thus, mitigation of waste plastics generation is one of the major challenges in the present situation. The present study addressed the conversion of waste plastics into value-added products such as liquid hydrocarbon fuels and their application in reducing greenhouse gas emissions. A comprehensive investigation has been performed on engine performance and combustion characteristics at various compression ratios and PO blending. The effect of liquid fuel blending with commercial diesel was investigated at three different compression ratios (15.1, 16.2, and 16.7) under various BMEP conditions. The results revealed that blending of liquid fuel produced from waste plastic can improve the BTE significantly, and the highest 35.77% of BTE was observed for 10% blending at 15.1 CR. While the lowest BSFC of 5.77 × 10 -5  kg/kW-s was estimated for 20% PO blending at 16.7 CR under optimum BMEP (4.0 bar) conditions. The investigation of combustion parameters such as cylinder pressure, net heat release rate, rate of pressure rise, and cumulative heat release showed that it increases with the compression ratio from 15.1 to 16.7. At the same time, the emissions of CO, CO 2 , and unburnt hydrocarbon was decreased significantly. The economic analysis for the present lab-scale study estimated that approximately ₹12.17 ($0.15) profit per liter is possible in the 1st year, while the significant profit starts from the 2nd year onward, which is in the range of ₹59.78-₹84.48 ($0.75-$1.07) when the PO is blended with CD within the permissible limits as per the norms., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)