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136 results on '"Chaffaut, Cendrine"'

1. Clinical impact of genetic alterations including germline DDX41 mutations in MDS/low-blast count AML patients treated with azacitidine-based regimens

Author

Sébert, Marie, Freiman, Lucie, Chaffaut, Cendrine, Guerci, Agnès, Peterlin, Pierre, Thépot, Sylvain, Beyne-Rauzy, Odile, Park, Sophie, Cluzeau, Thomas, Chermat, Fatiha, Fenaux, Pierre, Preudhomme, Claude, Clappier, Emmanuelle, Chevret, Sylvie, Adès, Lionel, Duployez, Nicolas, and Duchmann, Matthieu

Published
2024
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3. Hepatocyte-derived biomarkers predict liver-related events at 2 years in Child-Pugh class A alcohol-related cirrhosis

Author

Elkrief, Laure, Ganne-Carrié, Nathalie, Manceau, Hana, Tanguy, Marion, Valainathan, Shantha Ram, Riescher-Tuczkiewicz, Alix, Biquard, Louise, Barget, Nathalie, Chaffaut, Cendrine, Louvet, Alexandre, Paradis, Valérie, Ziol, Marianne, Bæk, Rikke, Jørgensen, Malene Møller, Van Niel, Guillaume, Coly, Pierre-Michael, Hammoutène, Adel, Dujardin, Fanny, Peoc’h, Katell, Poynard, Thierry, Chevret, Sylvie, and Rautou, Pierre-Emmanuel

Published
2023
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4. Integrating genetic variants into clinical models for hepatocellular carcinoma risk stratification in cirrhosis

Author

Nahon, Pierre, Asselah, Tarik, Guyader, Dominique, Pol, Stanislas, Fontaine, Hélène, Pageaux, Georges-Philippe, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Roulot, Dominique, Tran, Albert, Bronowicki, Jean-Pierre, Decaensi, Thomas, Riachi, Ghassan, Calès, Paul, Péron, Jean-Marie, Alric, Laurent, Bourlière, Marc, Mathurin, Philippe, Dharancy, Sebastien, Blanc, Jean-Frédéric, Abergel, Armand, Chazouillères, Olivier, Mallat, Ariane, Grangé, Jean-Didier, Attali, Pierre, Louis d’Alteroche, Wartelle, Claire, Dao, Thông, Thabut, Dominique, Pilette, Christophe, Silvain, Christine, Christidis, Christos, Nguyen-Khac, Eric, Bernard-Chabert, Brigitte, Hillaire, Sophie, Di Martino, Vincent, Ganne-Carrié, Nathalie, Chaffaut, Cendrine, Archambeaud, Isabelle, d’Alteroche, Louis, Oberti, Frédéric, Moreno, Christophe, Louvet, Alexandre, Moirand, Romain, Goria, Odile, Carbonell, Nicolas, Duclos-Vallée, Jean-Charles, de Ledinghen, Victor, Ozenne, Violaine, Henrion, Jean, Perlemuter, Gabriel, Amiot, Xavier, Zarski, Jean-Pierre, Chevret, Sylvie, Bamba-Funck, Jessica, Layese, Richard, Trépo, Eric, Zucman-Rossi, Jessica, Cagnot, Carole, Guyot, Erwan, Ziol, Marianne, Sutton, Angela, and Audureau, Etienne

Published
2023
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5. Low alcohol consumption influences outcomes in individuals with alcohol-related compensated cirrhosis in a French multicenter cohort

Author

Ganne-Carrié, Nathalie, Bourcier, Valérie, Chaffaut, Cendrine, Chevret, Sylvie, Archambeaud, Isabelle, Gournay, Jérôme, Louis d’Alteroche, Elkrief, Laure, Oberti, Frédéric, Fouchard-Hubert, Isabelle, Roulot, Dominique, Moreno, Christophe, Louvet, Alexandre, Dao, Thông, Moirand, Romain, Duclos-Vallée, Jean-Charles, Goria, Odile, Nguyen-Khac, Eric, Pol, Stanislas, Carbonell, Nicolas, Péron, Jean-Marie, de Lédinghen, Victor, Ozenne, Violaine, Henrion, Jean, Tran, Albert, Perlemuter, Gabriel, Amiot, Xavier, Zarski, Jean-Pierre, and d’Alteroche, Louis

Published
2023
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6. Early hepatocellular carcinoma detection using magnetic resonance imaging is cost-effective in high-risk patients with cirrhosis

Author

Nahon, Pierre, Asselah, Tarik, Guyader, Dominique, Pol, Stanislas, Fontaine, Hélène, Pageaux, Georges-Philippe, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Roulot, Dominique, Tran, Albert, Bronowicki, Jean-Pierre, Decaensi, Thomas, Riachi, Ghassan, Calès, Paul, Péron, Jean-Marie, Alric, Laurent, Bourlière, Marc, Mathurin, Philippe, Dharancy, Sebastien, Blanc, Jean-Frédéric, Abergel, Armand, Chazouillères, Olivier, Mallat, Ariane, Grangé, Jean-Didier, Attali, Pierre, d’Alteroche, Louis, Wartelle, Claire, Dao, Thông, Thabut, Dominique, Pilette, Christophe, Silvain, Christine, Christidis, Christos, Nguyen-Khac, Eric, Bernard-Chabert, Brigitte, Hillaire, Sophie, Di Martino, Vincent, Bonnet, Delphine, Payssan-Sicart, Virginie, Pomes, Chloe, Bailly, François, Beaudoin, Marjolaine, Giboz, Dominique, Hartig-Lavie, Kerstin, Maynard, Marianne, Billaud, Eric, Boutoille, David, Cavellec, Morane, Cheraud-Carpentier, Marjorie, Hubert, Isabelle, Benhida, Jaouad, Lannes, Adrien, Lunel, Françoise, Oberti, Frédéric, Boyer, Nathalie, Giuily, Nathalie, Castelnau, Corinne, Scoazec, Giovanna, Chibah, Aziza, Keser, Sylvie, Bonardi, Karim, Vallet-Pichard, Anaïs, Sogni, Philippe, Foucher, Juliette, Hiriart, Jean-Baptiste, Wilson, Amy, Shili, Sarah, Chermak, Faiza, Ansaldi, Christelle, Ben Amara, Nisserine, Chouquet, Laëtitia, De Luca, Emilie, Oules, Valérie, Anty, Rodolphe, Gelsi, Eve, Truchi, Régine, Luckina, Elena, Messaoudi, Nadia, Moussali, Joseph, De Dieuleveult, Barbara, Labarriere, Damien, Poter, Pascal, Si Ahmed, Si Nafa, Grando-Lemaire, Véronique, Bourcier, Valérie, Brulé, Séverine, Stalhberger, Thomas, Jezequel, Caroline, Brener, Audrey, Laligant, Anne, Rabot, Aline, Renard, Isabelle, Baumert, Thomas F., Dofföel, Michel, Mutter, Catherine, Simo-Noumbissie, Pauline, Razi, Esma, Barraud, Hélène, Bensenane, Mouni, Nani, Abdelbasset, Hassani-Nani, Sarah, Bernard, Marie-Albertine, Bismuth, Michael, Caillo, Ludovic, Faure, Stéphanie, Ripault, Marie Pierre, Bureau, Christophe, Peron, Jean Marie, Robic, Marie Angèle, Tarallo, Léa, Faure, Marine, Froissart, Bruno, Hilleret, Marie-Noelle, Zarski, Jean-Pierre, Goria, Odile, Grard, Victorien, Montialoux, Hélène, François, Muriel, Ouedraogo, Christian, Pauleau, Christelle, Varault, Anne, Andreani, Tony, Angoulevant, Bénédicte, Chevance, Azeline, Serfaty, Lawrence, Antonini, Teresa, Coilly, Audrey, Duclos Vallée, Jean-Charles, Tateo, Mariagrazia, Bonny, Corinne, Brigitte, Chanteranne, Lamblin, Géraldine, Muti, Léon, Babouri, Abdenour, Filipe, Virginie, Barrault, Camille, Costes, Laurent, Hagège, Hervé, Merbah, Soraya, Carrier, Paul, Debette-Gratien, Maryline, Jacques, Jérémie, Lassailly, Guillaume, Artu, Florent, Canva, Valérie, Dharancy, Sébastien, Louvet, Alexandre, Latournerie, Marianne, Bardou, Marc, Mouillot, Thomas, Bacq, Yannick, Barbereau, Didier, Nicolas, Charlotte, Chevalier, Caroline, Archambeaud, Isabelle, Habes, Sarah, Botta-Fridlund, Danièle, Saillard, Eric, Lafrance, Marie-Josée, Cacoub, Patrice, Carrat, Fabrice, Carrieri, Patrizia, Delarocque-Astagneau, Elisabeth, De Ledinghen, Victor, Dorival, Céline, Dubuisson, Jean, Housset, Chantal, Larrey, Dominique, Marcellin, Patrick, Pawlotsky, Jean-Michel, Petrov-Sanchez, Ventzislava, Vaux, Sophie, Wittkop, Linda, Yazdanpanah, Yazdan, Zucman-Rossi, Jessica, Ganne-Carrié, Nathalie, Chaffaut, Cendrine, Moreno, Christophe, Moirand, Romain, Carbonell, Nicolas, Duclos-Vallée, Jean-Charles, de Ledinghen, Victor, Ozenne, Violaine, Henrion, Jean, Perlemuter, Gabriel, Amiot, Xavier, Chevret, Sylvie, Najean, Marie, Layese, Richard, Zarca, Kevin, Segar, Laeticia Blampain, Cagnot, Carole, N’Kontchou, Gisèle, Ronot, Maxime, Audureau, Etienne, and Durand-Zaleski, Isabelle

Published
2022
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7. Impact of cirrhosis aetiology on incidence and prognosis of hepatocellular carcinoma diagnosed during surveillance

Author

Ganne-Carrié, Nathalie, Chaffaut, Cendrine, Archambeaud, Isabelle, d’Alteroche, Louis, Oberti, Frédéric, Roulot, Dominique, Moreno, Christophe, Louvet, Alexandre, Dao, Thông, Moirand, Romain, Goria, Odile, Nguyen-Khac, Eric, Carbonell, Nicolas, Duclos-Vallée, Jean-Charles, Pol, Stanislas, de Ledinghen, Victor, Ozenne, Violaine, Henrion, Jean, Péron, Jean-Marie, Tran, Albert, Perlemuter, Gabriel, Amiot, Xavier, Zarski, Jean-Pierre, Chevret, Sylvie, Nahon, Pierre, Asselah, Tarik, Guyader, Dominique, Fontaine, Hélène, Pageaux, Georges-Philippe, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Bronowicki, Jean-Pierre, Decaens, Thomas, Riachi, Ghassan, Calès, Paul, Alric, Laurent, Bourlière, Marc, Mathurin, Philippe, Dharancy, Sebastien, Blanc, Jean-Frédéric, Abergel, Armand, Chazouillères, Olivier, Mallat, Ariane, Grangé, Jean-Didier, Attali, Pierre, Wartelle, Claire, Thabut, Dominique, Pilette, Christophe, Silvain, Christine, Christidis, Christos, Bernard-Chabert, Brigitte, Hillaire, Sophie, Di Martino, Vincent, N’Kontchou, Gisèle, Layese, Richard, and Audureau, Etienne

Published
2021
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8. Estimate of hepatocellular carcinoma incidence in patients with alcoholic cirrhosis

Author

Ganne-Carrié, Nathalie, Chaffaut, Cendrine, Bourcier, Valérie, Archambeaud, Isabelle, Perarnau, Jean-Marc, Oberti, Frédéric, Roulot, Dominique, Moreno, Christophe, Louvet, Alexandre, Dao, Thông, Moirand, Romain, Goria, Odile, Nguyen-Khac, Eric, Carbonell, Nicolas, Antonini, Térésa, Pol, Stanislas, de Ledinghen, Victor, Ozenne, Violaine, Henrion, Jean, Péron, Jean-Marie, Tran, Albert, Perlemuter, Gabriel, Amiot, Xavier, Zarski, Jean-Pierre, Beaugrand, Michel, and Chevret, Sylvie

Published
2018
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9. The clinical and financial burden of nonhepatocellular carcinoma focal lesions detected during the surveillance of patients with cirrhosis.

Author

Nahon, Pierre, Layese, Richard, Ganne-Carrié, Nathalie, Moins, Cécile, N'Kontchou, Gisèle, Chaffaut, Cendrine, Ronot, Maxime, Audureau, Etienne, Durand-Zaleski, Isabelle, Natella, Pierre-André, Asselah, Tarik, Guyader, Dominique, Pol, Stanislas, Fontaine, Hélène, Pageaux, Georges-Philippe, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Roulot, Dominique, and Tran, Albert

Published
2024
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11. Clinical impact of genetic alterations including germline DDX41mutations in MDS/low-blast count AML patients treated with azacitidine-based regimens

Author

Sébert, Marie, Freiman, Lucie, Chaffaut, Cendrine, Guerci, Agnès, Peterlin, Pierre, Thépot, Sylvain, Beyne-Rauzy, Odile, Park, Sophie, Cluzeau, Thomas, Chermat, Fatiha, Fenaux, Pierre, Preudhomme, Claude, Clappier, Emmanuelle, Chevret, Sylvie, Adès, Lionel, Duployez, Nicolas, and Duchmann, Matthieu

Published
2024
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14. ABO blood group does not influence Child‐Pugh A cirrhosis outcome: An observational study from CIRRAL and ANRS CO12 CIRVIR cohorts

Author

Ollivier-Hourmand, Isabelle, Repesse, yohann, Nahon, Pierre, Chaffaut, Cendrine, Dao, Thông, Nguyen, Thi Thu Nga, Marcellin, Patrick, Roulot, Dominique, de Ledinghen, Victor, Pol, Stanislas, Guyader, Dominique, Archambeaud, Isabelle, Zoulim, Fabien, Oberti, Frédéric, Tran, Albert, Bronowicki, Jean-Pierre, d'Alteroche, Louis, Ouzan, Denis, Peron, Jean-Marie, Zarski, Jean-Pierre, Bourliere, Marc, Larrey, Dominique, Louvet, Alexandre, Cales, Paul, Abergel, Armand, Mathurin, Philippe, Mallat, Ariane, Blanc, Jean-Frederic, Nguyen-Khac, Eric, Riachi, Ghassan, Alric, Laurent, Serfaty, Lawrence, Antonini, Teresa, Moreno, Christophe, Attali, Pierre, Thabut, Dominique, Pilette, Christophe, Grange, Jean-Didier, Silvain, Christine, Carbonell, Nicolas, Bernard-Chabert, Brigitte, Goria, Odile, Wartelle, Claire, Moirand, Romain, Christidis, Christos, Perlemuter, Gabriel, Ozenne, Violaine, Henrion, Jean, Hillaire, Sophie, Di Martino, Vincent, Amiot, Xavier, Sutton, Angela, Barget, Nathalie, Chevret, Sylvie, Ganne‐carrie, Nathalie, CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPC), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université (HESAM)-HESAM Université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPC)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital Avicenne [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPC), Nutrition, Métabolismes et Cancer (NuMeCan), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), CHU Pontchaillou [Rennes], Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), Institut Arnault Tzanck, Service de Gastro-entérologie - Hépatologie [Purpan], CHU Toulouse [Toulouse], CHU Grenoble, Groupe de Recherche sur l'alcool et les pharmacodépendances - UMR INSERM_S 1247 (GRAP), Université de Picardie Jules Verne (UPJV)-Institut National de la Santé et de la Recherche Médicale (INSERM), Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau (ADEN), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service d'Hépato-Gastroentérologie [CHU Rouen], Hôpital Charles Nicolle [Rouen]-CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Normandie Université (NU)-Normandie Université (NU), Immunologie et virologie des cancers. Immunologie des interactions cellulaires et moléculaires (Inserm U152), Institut National de la Santé et de la Recherche Médicale (INSERM), Equipe 2 : ECSTRA - Epidémiologie Clinique, STatistique, pour la Recherche en Santé (CRESS - U1153), HESAM Université (HESAM)-HESAM Université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPC)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), This work was supported by a research grant from the French National Society of Gastroenterology (SNFGE), a research grant from the French Agency for Research on AIDS and Viral Hepatitis (ANRS), and a research grant from Abbvie., École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Pôle Maladies de l'appareil digestif [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Hôpital Charles Nicolle [Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-CHU Rouen, and HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)

Subjects
Liver Cirrhosis, Hepatology, [SDV]Life Sciences [q-bio], alcoholic cirrhosis, ABO blood group, non-malignant portal vein thrombosis, ABO Blood-Group System, Hypertension, Portal, Disease Progression, outcome, Humans, Prospective Studies, viral cirrhosis, Child-Pugh A cirrhosis
Abstract

International audience; Background and aims: Non-O blood group promotes deep vein thrombosis and liver fibrosis in both general population and hepatitis C. We aimed to evaluate the influence of Non-O group on the outcome of Child-Pugh A cirrhotic patients.Methods: We used two prospective cohorts of Child-Pugh A cirrhosis due to either alcohol or viral hepatitis. Primary end point was the cumulated incidence of 'Decompensation' at 3 years, defined as the occurrence of ascites , hydrothorax, encephalopathy, gastrointestinal bleeding related to portal hypertension, or bilirubin >45 μmol/L. Secondary end points were the cumulated incidences of (1) 'Disease Progression' including a « decompensation» or « the occurrence of one or more parameters » among: prothrombin time (PT)

Published
2022

15. Decitabine Versus Hydroxyurea for Advanced Proliferative Chronic Myelomonocytic Leukemia: Results of a Randomized Phase III Trial Within the EMSCO Network

Author

Itzykson, Raphael, primary, Santini, Valeria, additional, Thepot, Sylvain, additional, Ades, Lionel, additional, Chaffaut, Cendrine, additional, Giagounidis, Aristoteles, additional, Morabito, Margot, additional, Droin, Nathalie, additional, Lübbert, Michael, additional, Sapena, Rosa, additional, Nimubona, Stanislas, additional, Goasguen, Jean, additional, Wattel, Eric, additional, Zini, Gina, additional, Torregrosa Diaz, Jose Miguel, additional, Germing, Ulrich, additional, Pelizzari, Anna Maria, additional, Park, Sophie, additional, Jaekel, Nadja, additional, Metzgeroth, Georgia, additional, Onida, Francesco, additional, Navarro, Robert, additional, Patriarca, Andrea, additional, Stamatoullas, Aspasia, additional, Götze, Katharina, additional, Puttrich, Martin, additional, Mossuto, Sandra, additional, Solary, Eric, additional, Gloaguen, Silke, additional, Chevret, Sylvie, additional, Chermat, Fatiha, additional, Platzbecker, Uwe, additional, and Fenaux, Pierre, additional

Published
2022
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16. Empirical Antibiotic Therapy for Gram-Negative Bacilli Ventilator-Associated Pneumonia: Observational Study and Pharmacodynamic Assessment

Author

Pajot, Olivier, primary, Lakhal, Karim, additional, Lambert, Jérome, additional, Gros, Antoine, additional, Bruel, Cédric, additional, Boulain, Thierry, additional, Garot, Denis, additional, Das, Vincent, additional, Timsit, Jean François, additional, Cerf, Charles, additional, Souweine, Bertrand, additional, Chaffaut, Cendrine, additional, Mentec, Hervé, additional, Zahar, Jean Ralph, additional, Mira, Jean Paul, additional, and Jullien, Vincent, additional

Published
2022
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17. Final Results of Ruxopeg, a Phase 1/2 Adaptive Randomized Trial of Ruxolitinib (Rux) and Pegylated Interferon Alpha (IFNa) 2a in Patients with Myelofibrosis (MF)

Author

Kiladjian, Jean-Jacques, primary, Ianotto, Jean-Christophe, additional, Soret, Juliette, additional, Maslah, Nabih, additional, Chaffaut, Cendrine, additional, Boyer perrard, Françoise, additional, Barraco, Fiorenza, additional, Dubruille, Viviane, additional, Capron, Claude, additional, Tisserand, Amandine, additional, Rolland-Neyret, Valérie, additional, Ghrieb, Zineb, additional, Chevret, Sylvie, additional, Plo, Isabelle, additional, Schlageter, Marie-Hélène, additional, Meignin, Veronique, additional, Resche-Rigon, Matthieu, additional, and Cassinat, Bruno, additional

Published
2022
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19. Liver Stiffness by Transient Elastography to Detect Porto‐Sinusoidal Vascular Liver Disease With Portal Hypertension

Author

Elkrief, Laure, Lazareth, Marie, Chevret, Sylvie, Paradis, Valérie, Magaz, Marta, Blaise, Lorraine, Rubbia‐Brandt, Laura, Moga, Lucile, Durand, François, Payancé, Audrey, Plessier, Aurélie, Chaffaut, Cendrine, Valla, Dominique, Malphettes, Marion, Diaz, Alba, Nault, Jean‐Charles, Nahon, Pierre, Audureau, Etienne, Ratziu, Vlad, Castera, Laurent, Garcia Pagan, Juan‐Carlos, Ganne‐Carrie, Nathalie, Rautou, Pierre‐Emmanuel, Marcellin, Patrick, Guyader, Dominique, Pol, Stanislas, Fontaine, Hélène, Larrey, Dominique, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Roulot, Dominique, Tran, Albert, Bronowicki, Jean‐Pierre, Zarski, Jean‐Pierre, Leroy, Vincent, Riachi, Ghassan, Calès, Paul, Péron, Jean‐Marie, Alric, Laurent, Bourlière, Marc, Mathurin, Philippe, Dharancy, Sebastien, Blanc, Jean‐Frédéric, Abergel Olivier Chazouillères, Armand, Mallat, Ariane, Grangé, Jean‐Didier, Attali, Pierre, Bacq, Yannick, Wartelle, Claire, Dao, Thông, Thabut, Dominique, Pilette, Christophe, Silvain, Christine, Christidis, Christos, Nguyen‐Khac, Eric, Bernard‐Chabert, Brigitte, Zucman, David, and Di Martino, Vincent

Subjects
0301 basic medicine, medicine.medical_specialty, Cirrhosis, Hepatology, business.industry, Hepatitis C virus, Fatty liver, medicine.disease, medicine.disease_cause, Gastroenterology, 03 medical and health sciences, Liver disease, 030104 developmental biology, 0302 clinical medicine, Esophageal varices, Internal medicine, Ascites, medicine, Portal hypertension, 030211 gastroenterology & hepatology, medicine.symptom, Transient elastography, business
Abstract

Background & aims Porto-sinusoidal vascular liver disease (PSVD) is a rare cause of portal hypertension. PSVD is still often misdiagnosed as cirrhosis, emphasizing the need to improve PSVD diagnosis strategies. Data on liver stiffness measurement (TE-LSM) using transient elastography, in PSVD are limited. The aim of this study was to evaluate the accuracy of TE-LSM to discriminate PSVD from cirrhosis in patients with signs of portal hypertension. Approach & results Retrospective multicenter study comparing TE-LSM in patients with PSVD, according to VALDIG criteria, to patients with compensated biopsy-proven cirrhosis related to alcohol (n=117), hepatitis C virus (HCV) infection (n=110) or non-alcoholic fatty liver disease (NAFLD) (n=46). All patients had at least one sign of portal hypertension among gastroesophageal varices, splenomegaly, porto-systemic collaterals, history of ascites or platelet count Conclusions This study including a total of 155 patients with PSVD and 273 patients with cirrhosis demonstrates that TE-LSM 20 kPa, PSVD is highly unlikely.

Published
2021

20. Hepatocyte-derived biomarkers concentrations predict liver-related events within 2 years in patients with Child-Pugh class A alcohol-related cirrhosis

Author

Elkrief, Laure, primary, Ganne-Carrié, Nathalie, additional, Manceau, Hana, additional, Tanguy, Marion, additional, Barget, Nathalie, additional, Chaffaut, Cendrine, additional, Valainathan, Shantha, additional, Riescher, Alix, additional, Peoch, Katell, additional, Poynard, Thierry, additional, Chevret, Sylvie, additional, and Rautou, Pierre-Emmanuel, additional

Published
2022
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21. Integrating genetic variants into clinical models for hepatocellular carcinoma risk stratification in cirrhosis.

Author

Nahon, Pierre, Bamba-Funck, Jessica, Layese, Richard, Trepo, Eric, Zucman-Rossi, Jessica, Cagnot, Carole, Ganne-Carrié, Nathalie, Chaffaut, Cendrine, Guyot, Erwan, Ziol, Marianne, Sutton, Angela, Audureau, Etienne, ANRS CO12 CirVir and CIRRAL groups, Nahon, Pierre, Bamba-Funck, Jessica, Layese, Richard, Trepo, Eric, Zucman-Rossi, Jessica, Cagnot, Carole, Ganne-Carrié, Nathalie, Chaffaut, Cendrine, Guyot, Erwan, Ziol, Marianne, Sutton, Angela, Audureau, Etienne, and ANRS CO12 CirVir and CIRRAL groups

Abstract

Identifying individuals at higher risk of developing hepatocellular carcinoma (HCC) is pivotal to improve the performance of surveillance strategies. Herein, we aimed to evaluate the ability of single nucleotide polymorphisms (SNPs) to refine HCC risk stratification., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2022

22. Decitabine Versus Hydroxyurea for Advanced Proliferative Chronic Myelomonocytic Leukemia: Results of a Randomized Phase III Trial Within the EMSCO Network.

Author

Itzykson, Raphael, Santini, Valeria, Thepot, Sylvain, Ades, Lionel, Chaffaut, Cendrine, Giagounidis, Aristoteles, Morabito, Margot, Droin, Nathalie, Lübbert, Michael, Sapena, Rosa, Nimubona, Stanislas, Goasguen, Jean, Wattel, Eric, Zini, Gina, Torregrosa Diaz, Jose Miguel, Germing, Ulrich, Pelizzari, Anna Maria, Park, Sophie, Jaekel, Nadja, and Metzgeroth, Georgia

Published
2023
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24. Ivosidenib Monotherapy Is Effective in Patients with IDH1 Mutated Myelodysplastic Syndrome (MDS): The Idiome Phase 2 Study By the GFM Group

Author

Sebert, Marie, primary, Cluzeau, Thomas, additional, Beyne Rauzy, Odile, additional, Stamatoulas Bastard, Aspasia, additional, Dimicoli-Salazar, Sophie, additional, Thepot, Sylvain, additional, Peterlin, Pierre, additional, Park, Sophie, additional, Gourin, Marie-Pierre, additional, Brehar, Oana, additional, Bally, Cécile, additional, Maury, Sébastien, additional, Fossard, Gaelle, additional, Ait Si Selmi, Lamya, additional, Chaffaut, Cendrine, additional, Clappier, Emmanuelle, additional, Itzykson, Raphael, additional, Chermat, Fatiha, additional, Chevret, Sylvie, additional, Fenaux, Pierre, additional, and Ades, Lionel, additional

Published
2021
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25. Allogeneic Hematopoietic Stem Cell Transplantation (allo HSCT) in Patients with IPSS Low or Intermediate-1 Myelodysplastic Syndrome (MDS): A Prospective Multicenter Phase II Study Based on Donor Availability By the GFM & SFGM-TC "MDS-ALLO-Risk"

Author

Sebert, Marie, primary, Chaffaut, Cendrine, additional, Thepot, Sylvain, additional, Orvain, Corentin, additional, Cluzeau, Thomas, additional, Loschi, Michael, additional, Peterlin, Pierre, additional, Chevallier, Patrice, additional, d'Aveni, Maud, additional, Rubio, Marie-Thérèse, additional, Beyne Rauzy, Odile, additional, Huynh, Anne, additional, Charbonnier, Amandine, additional, Fegueux, Nathalie, additional, Fossard, Gaelle, additional, N'guyen-Quoc, Stephanie, additional, Park, Sophie, additional, Sapena, Rosa, additional, Chermat, Fatiha, additional, Ades, Lionel, additional, Chevret, Sylvie, additional, Fenaux, Pierre, additional, and Robin, Marie, additional

Published
2021
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26. Complications and competing risks of death in compensated viral cirrhosis (ANRS CO12 CirVir prospective cohort)

Author

Trinchet, Jean-Claude, Bourcier, Valérie, Chaffaut, Cendrine, Ait Ahmed, Mohand, Allam, Setty, Marcellin, Patrick, Guyader, Dominique, Pol, Stanislas, Larrey, Dominique, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Roulot, Dominique, Tran, Albert, Bronowicki, Jean-Pierre, Zarski, Jean-Pierre, Goria, Odile, Calès, Paul, Péron, Jean-Marie, Alric, Laurent, Bourlière, Marc, Mathurin, Philippe, Blanc, Jean-Frédéric, Abergel, Armand, Serfaty, Lawrence, Mallat, Ariane, Grangé, Jean-Didier, Buffet, Catherine, Bacq, Yannick, Wartelle, Claire, Dao, Thông, Benhamou, Yves, Pilette, Christophe, Silvain, Christine, Christidis, Christos, Capron, Dominique, Thiefin, Gérard, Hillaire, Sophie, Di Martino, Vincent, Nahon, Pierre, and Chevret, Sylvie

Published
2015
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28. Drivers of outcome in compensated alcohol-related cirrhosis: a prospective study

Author

Louvet, Alexandre, Chaffaut, Cendrine, Gournay, Jerome, Oberti, Frederic, Elkrief, Laure, Dao, Thong, Moreno, Christophe, Duclos-Vallee, Jean-Charles, Roulot, Dominique, Moirand, Romain, Nguyen-Khac, Eric, Chevret, Sylvie, Ganne-Carrie, Nathalie, Institute for Translational Research in Inflammation - U 1286 (INFINITE (Ex-Liric)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Service de biostatistique et information médicale de l’hôpital Saint Louis (Equipe ECSTRA) (SBIM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut national du cancer [Boulogne] (INCA)-Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Cité (UPCité), Equipe 2 : ECSTRA - Epidémiologie Clinique, STatistique, pour la Recherche en Santé (CRESS - U1153), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut des Maladies de l'Appareil Digestif, Université de Nantes (UN), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Service d'Hépato-Gastro-Enterologie et Nutrition [CHU Caen], Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), Physiopathologie et traitement des maladies du foie, Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, DHU Hepatinov [Villejuif], Hôpital Paul Brousse, Chercheur indépendant, Nutrition, Métabolismes et Cancer (NuMeCan), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), CHU Pontchaillou [Rennes], Groupe de Recherche sur l'alcool et les pharmacodépendances - UMR INSERM_S 1247 (GRAP), Université de Picardie Jules Verne (UPJV)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'Hépato Gastroenterologie [CHU Amiens-Picardie], CHU Amiens-Picardie, Hôpital Avicenne [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Sorbonne Paris Nord, Génomique fonctionnelle des tumeurs solides = Functional Genomics of Solid Tumors [CRC] (FunGeST), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-École Pratique des Hautes Études (EPHE), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)

Subjects
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

International audience

Published
2021

29. PERSISTENT MODERATE ALCOHOL CONSUMPTION IMPACTS SURVIVAL IN PATIENTS WITH COMPENSATED ALCOHOL-RELATED CIRRHOSIS: ANALYSIS OF THE CIRRAL COHORT

Author

Louvet, Alexandre, Chaffaut, Cendrine, Mabile, Isabelle Archambeaud, Oberti, Frederic, Alteroche, Louis D., Dao, Thong, Moreno, Christophe, Duclos-Vallee, Jean-Charles, Marullo, Dominique Roulot, Moirand, Romain, Nguyen-Khac, Eric, Chevret, Sylvie, Carrie, Nathalie Ganne, Institute for Translational Research in Inflammation - U 1286 (INFINITE (Ex-Liric)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Service de biostatistique et information médicale de l’hôpital Saint Louis (Equipe ECSTRA) (SBIM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut national du cancer [Boulogne] (INCA)-Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Cité (UPCité), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Service d'Hépato-Gastro-Enterologie et Nutrition [CHU Caen], Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), Physiopathologie et traitement des maladies du foie, Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, DHU Hepatinov [Villejuif], Hôpital Paul Brousse, Nutrition, Métabolismes et Cancer (NuMeCan), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), CHU Pontchaillou [Rennes], Groupe de Recherche sur l'alcool et les pharmacodépendances - UMR INSERM_S 1247 (GRAP), Université de Picardie Jules Verne (UPJV)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Service d'Hépato-gastroentérologie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Jean Verdier [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), and DESSAIVRE, Louise

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2021

30. Nutritional status, swallowing disorders, and respiratory prognosis in adult Duchenne muscular dystrophy patients

Author

Fayssoil, Abdallah, primary, Chaffaut, Cendrine, additional, Prigent, Helene, additional, Laforet, Pascal, additional, Clair, Bernard, additional, Orlikowski, David, additional, Ogna, Adam, additional, Chevret, Sylvie, additional, Meng, Paris, additional, Annane, Djillali, additional, Lofaso, Frederic, additional, and Crenn, Pascal, additional

Published
2021
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32. Ultrasonographic surveillance of hepatocellular carcinoma in cirrhosis: A randomized trial comparing 3- and 6-month periodicities

Author

Trinchet, Jean-Claude, Chaffaut, Cendrine, Bourcier, Valérie, Degos, Françoise, Henrion, Jean, Fontaine, Hélène, Roulot, Dominique, Mallat, Ariane, Hillaire, Sophie, Cales, Paul, Ollivier, Isabelle, Vinel, Jean-Pierre, Mathurin, Philippe, Bronowicki, Jean-Pierre, Vilgrain, Valérie, NʼKontchou, Gisèle, Beaugrand, Michel, and Chevret, Sylvie

Published
2011
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33. Decitabine Versus Hydroxyurea for Advanced Proliferative CMML: Results of the Emsco Randomized Phase 3 Dacota Trial

Author

Itzykson, Raphael, primary, Santini, Valeria, additional, Chaffaut, Cendrine, additional, Lionel, Ades, additional, Thepot, Sylvain, additional, Giagounidis, Aristoteles, additional, Morabito, Margot, additional, Droin, Nathalie, additional, Luebbert, Michael, additional, Sapena, Rosa, additional, Nimubona, Stanislas, additional, Goasguen, Jean E., additional, Wattel, Eric, additional, Zini, Gina, additional, Torregrosa Diaz, Jose Miguel, additional, Germing, Ulrich, additional, Pelizzari, Anna Maria, additional, Park, Sophie, additional, Jaekel, Nadja, additional, Metzgeroth, Georgia, additional, Onida, Francesco, additional, Navarro, Robert, additional, Patriarca, Andrea, additional, Stamatoulas Bastard, Aspasia, additional, Puttrich, Martin, additional, Mossuto, Sandra, additional, Solary, Eric, additional, Gloaguen, Silke, additional, Chevret, Sylvie, additional, Chermat, Fatiha, additional, Platzbecker, Uwe, additional, and Fenaux, Pierre, additional

Published
2020
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34. Nutritional status, swallowing disorders and respiratory prognosis in adult Duchenne muscular dystrophy patients

Author

Fayssoil, Abdallah, primary, CHAFFAUT, Cendrine, additional, PRIGENT, Helene, additional, LAFORET, Pascal, additional, CLAIR, Bernard, additional, ORLIKOWSKI, David, additional, OGNA, Adam, additional, CHEVRET, Sylvie, additional, MENG, Paris, additional, ANNANE, Djillali, additional, LOFASO, Frédéric, additional, and CRENN, Pascal, additional

Published
2020
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35. Liver stiffness by transient elastography to detect porto-sinusoidal vascular liver disease in patients with portal hypertension

Author

Elkrief, Laure, primary, Marie, Lazareth, additional, Chevret, Sylvie, additional, Paradis, Valérie, additional, Rubbia-Brandt, Laura, additional, Durand, Francois, additional, Laurent, Castera, additional, Audrey, Payance, additional, Marion, Malphettes, additional, Plessier, Aurélie, additional, Chaffaut, Cendrine, additional, Audureau, Etienne, additional, Valla, Dominique, additional, Nahon, Pierre, additional, Ganne-Carrié, Nathalie, additional, and Rautou, Pierre-Emmanuel, additional

Published
2020
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36. Prognosis of alcoholic or viral B/C cirrhosis according to ABO blood group: results of abocirralvir, from CIRRAL and ANRS CO12 CirVir cohorts

Author

Ollivier-Hourmand, Isabelle, primary, Nahon, Pierre, additional, Chaffaut, Cendrine, additional, Dao, Thong, additional, Nguyen, Nga, additional, Patrick, Marcellin, additional, Roulot, Dominique, additional, de Lédinghen, Victor, additional, Pol, Stanislas, additional, Guyader, Dominique, additional, Mabile-Archambeaud, Isabelle, additional, Zoulim, Fabien, additional, Oberti, Frédéric, additional, Tran, Albert, additional, Bronowicki, Jean-Pierre, additional, Dalteroche, Louis, additional, Ouzan, Denis, additional, Peron, Jean Marie, additional, Zarski, Jean-Pierre, additional, Bourliere, Marc, additional, Larrey, Dominique, additional, Louvet, Alexandre, additional, Cales, Paul, additional, Abergel, Armand, additional, Mathurin, Philippe, additional, Mallat, Ariane, additional, Blanc, Jean-Frédéric, additional, Khac, Eric Nguyen, additional, Riachi, Ghassan, additional, Alric, Laurent, additional, Serfaty, Lawrence, additional, Antonini, Tereza, additional, Moreno, Christophe, additional, Attali, Pierre, additional, Thabut, Dominique, additional, Pilette, Christophe, additional, Grange, Jean Didier, additional, Silvain, Christine, additional, Carbonell, Nicolas, additional, Chabert, Brigitte Bernard, additional, Goria, Odile, additional, Wartelle-Bladou, Claire, additional, Moirand, Romain, additional, Christidis, Christos, additional, Perlemuter, Gabriel, additional, Ozenne, Violaine, additional, Henrion, Jean, additional, Hillaire, Sophie, additional, Di Martino, Vincent, additional, Amiot, Xavier, additional, Sutton, Angela, additional, Barget, Nathalie, additional, Repesse, Yohann, additional, Chevret, Sylvie, additional, and Ganne-Carrié, Nathalie, additional

Published
2020
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37. Ultrasonographic surveillance of hepatocellular carcinoma in cirrhosis: A randomized trial comparing 3- and 6-month periodicities

Author

Trinchet, Jean-Claude, Chaffaut, Cendrine, Bourcier, Valérie, Degos, Françoise, Henrion, Jean, Fontaine, Hélène, Roulot, Dominique, Mallat, Ariane, Hillaire, Sophie, Cales, Paul, Ollivier, Isabelle, Vinel, Jean-Pierre, Mathurin, Philippe, Bronowicki, Jean-Pierre, Vilgrain, Valérie, NʼKontchou, Gisèle, Beaugrand, Michel, and Chevret, Sylvie

Published
2010
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39. Left bundle branch block in Duchenne muscular dystrophy: Prevalence, genetic relationship and prognosis

Author

Fayssoil, Abdallah, Ben Yaou, Rabah, Ogna, Adam, Chaffaut, Cendrine, Leturcq, France, Nardi, Olivier, Wahbi, Karim, Duboc, Denis, Lofaso, Frederic, Prigent, Helene, Clair, Bernard, Crenn, Pascal, Nicolas, Guillaume, Laforet, Pascal, Behin, Anthony, Chevret, Sylvie, Orlikowski, David, and Annane, Djillali

Subjects
Adult, Male, Heredity, Genetic Linkage, Bundle-Branch Block, Cardiology, lcsh:Medicine, Duchenne Muscular Dystrophy, Biochemistry, Muscular Dystrophies, Dystrophin, Young Adult, Protein Domains, Diagnostic Medicine, Medicine and Health Sciences, Genetics, Prevalence, Point Mutation, Humans, Genetic Predisposition to Disease, lcsh:Science, Retrospective Studies, Heart Failure, Clinical Genetics, lcsh:R, Biology and Life Sciences, Proteins, Prognosis, Muscular Dystrophy, Duchenne, Cytoskeletal Proteins, Deletion Mutation, Neurology, X-Linked Traits, Sex Linkage, Mutation, Female, lcsh:Q, Research Article
Abstract

Background Duchenne muscular dystrophy (DMD) is an inherited myogenic disorder due to mutations in the dystrophin gene on chromosome Xp21.1. We designed this study to determine the prevalence of left bundle branch block (LBBB), whether there is a relationship between LBBB and genetic pattern, and to assess predictive factors for acute cardiac events and mortality in adult DMD patients. Methods We reviewed the charts of DMD followed at the Home Mechanical Ventilation Unit of the Raymond Poincare University Hospital. Results A total of 121 patients, aged from 18 to 41 years have been included in our study. Median vital capacity (VC) was 12% [7; 19.5] of predicted. Almost all patients were on home mechanical ventilation (95%). LBBB was present in 15 patients (13%); among them, 10 disclosed exonic deletions. After a median follow up of 6 years, 21 patients (17%) experienced acute heart failure (AHF), 7 patients (6%) supraventricular arrhythmia, 3 patients (2.4%) ventricular tachycardia, 4 patients (3%) significant electrical disturbances. LBBB was significantly associated with cardiac events (OR = 12.7; 95%CI [3.78–42.7]; p

Published
2018

40. A phase II study of guadecitabine in higher-risk myelodysplastic syndrome and low blast count acute myeloid leukemia after azacitidine failure

Author

Sébert, Marie, primary, Renneville, Aline, additional, Bally, Cécile, additional, Peterlin, Pierre, additional, Beyne-Rauzy, Odile, additional, Legros, Laurence, additional, Gourin, Marie-Pierre, additional, Sanhes, Laurence, additional, Wattel, Eric, additional, Gyan, Emmanuel, additional, Park, Sophie, additional, Stamatoullas, Aspasia, additional, Banos, Anne, additional, Laribi, Kamel, additional, Jueliger, Simone, additional, Bevan, Luke, additional, Chermat, Fatiha, additional, Sapena, Rosa, additional, Nibourel, Olivier, additional, Chaffaut, Cendrine, additional, Chevret, Sylvie, additional, Preudhomme, Claude, additional, Adès, Lionel, additional, and Fenaux, Pierre, additional

Published
2019
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41. Echographic Assessment of Diaphragmatic Function in Duchenne Muscular Dystrophy from Childhood to Adulthood

Author

Fayssoil, Abdallah, primary, Chaffaut, Cendrine, additional, Ogna, Adam, additional, Stojkovic, Tanya, additional, Lamothe, Laure, additional, Mompoint, Dominique, additional, Meng, Paris, additional, Prigent, Helene, additional, Clair, Bernard, additional, Behin, Anthony, additional, Laforet, Pascal, additional, Bassez, Guillaume, additional, Carlier, Robert, additional, Orlikowski, David, additional, Amthor, Helge, additional, Quijano Roy, Susana, additional, Crenn, Pascal, additional, Chevret, Sylvie, additional, Eymard, Bruno, additional, Lofaso, Frederic, additional, and Annane, Djillali, additional

Published
2019
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42. Lenalidomide combined with intensive chemotherapy in acute myeloid leukemia and higher-risk myelodysplastic syndrome with 5q deletion. Results of a phase II study by the Groupe Francophone Des Myélodysplasies

Author

Ades, Lionel, primary, Prebet, Thomas, additional, Stamatoullas, Aspasia, additional, Recher, Christian, additional, Guieze, Romain, additional, Raffoux, Emmanuel, additional, Bouabdallah, Krimo, additional, Hunault, Mathilde, additional, Wattel, Eric, additional, Stalnikiewicz, Laure, additional, Toma, Andrea, additional, Dombret, Hervé, additional, Vey, Norbert, additional, Sebert, Marie, additional, Gardin, Claude, additional, Chaffaut, Cendrine, additional, Chevret, Sylvie, additional, and Fenaux, Pierre, additional

Published
2016
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43. Results of a Phase II Study of Guadecitabine (SGI-110) in Higher Risk MDS, CMML or Low Blast Count AML Patients Refractory to or Relapsing after Azacitidine (AZA) Treatment

Author

Sebert, Marie, primary, Bally, Cecile, additional, Peterlin, Pierre, additional, Beyne-Rauzy, Odile, additional, Legros, Laurence, additional, Gourin, marie Pierre, additional, Sanhes, Laurence, additional, Wattel, Eric, additional, Gyan, Emmanuel, additional, Park, Sophie, additional, Stamatoullas, Aspasia, additional, Banos, Anne, additional, Laribi, Kamel, additional, Jueliger, Simone, additional, Bevan, Luke, additional, Chaffaut, Cendrine, additional, Sapena, Rosa, additional, Samey, Benedicte, additional, Chermat, Fatiha, additional, Chevret, Sylvie, additional, Ades, Lionel, additional, and Fenaux, Pierre, additional

Published
2016
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44. Prognostic Value of Initial Assessment of Residual Hypoventilation Using Nocturnal Capnography in Mechanically Ventilated Neuromuscular Patients: A 5-Year Follow-up Study

Author

Ogna, Adam, primary, Nardi, Julie, additional, Prigent, Helene, additional, Quera Salva, Maria-Antonia, additional, Chaffaut, Cendrine, additional, Lamothe, Laure, additional, Chevret, Sylvie, additional, Annane, Djillali, additional, Orlikowski, David, additional, and Lofaso, Frederic, additional

Published
2016
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45. Natural History of Cardiac and Respiratory Involvement, Prognosis and Predictive Factors for Long-Term Survival in Adult Patients with Limb Girdle Muscular Dystrophies Type 2C and 2D

Author

Fayssoil, Abdallah, primary, Ogna, Adam, additional, Chaffaut, Cendrine, additional, Chevret, Sylvie, additional, Guimarães-Costa, Raquel, additional, Leturcq, France, additional, Wahbi, Karim, additional, Prigent, Helene, additional, Lofaso, Frederic, additional, Nardi, Olivier, additional, Clair, Bernard, additional, Behin, Anthony, additional, Stojkovic, Tanya, additional, Laforet, Pascal, additional, Orlikowski, David, additional, and Annane, Djillali, additional

Published
2016
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46. Mechanisms Underpinning Increased Plasma Creatinine Levels in Patients Receiving Vemurafenib for Advanced Melanoma

Author

Hurabielle, Charlotte, primary, Pillebout, Evangéline, additional, Stehlé, Thomas, additional, Pagès, Cécile, additional, Roux, Jennifer, additional, Schneider, Pierre, additional, Chevret, Sylvie, additional, Chaffaut, Cendrine, additional, Boutten, Anne, additional, Mourah, Samia, additional, Basset-Seguin, Nicole, additional, Vidal-Petiot, Emmanuelle, additional, Lebbé, Céleste, additional, and Flamant, Martin, additional

Published
2016
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47. Azacitidine (AZA) Combined with Idarubicin in Higher Risk MDS - Results of a Phase I/II Study By the Groupe Francophone Des Myelodysplasies (GFM)

Author

Sebert, Marie, primary, Stamatoullas, Aspasia, additional, Braun, Thorsten, additional, Delaunay, Jacques, additional, de Renzis, Benoît, additional, Jeddi, Ramzi, additional, Meddeb, Balkis, additional, Hunault Berger, Mathilde, additional, Samey, Benedicte, additional, Chermat, Fatiha, additional, Chevret, Sylvie, additional, Chaffaut, Cendrine, additional, Fenaux, Pierre, additional, and Ades, Lionel, additional

Published
2015
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48. Mechanisms of elevated serum creatinine in patients receiving vemurafenib for advanced melanoma.

Author

Hurabielle, Charlotte, primary, Pillebout, Evangeline, additional, Stehle, Thomas, additional, Pagès, Cécile, additional, Roux, Jennifer, additional, Schneider, Pierre, additional, Chevret, Sylvie, additional, Mourah, Samia, additional, Basset-Seguin, Nicole, additional, Chaffaut, Cendrine, additional, Vidal-Petiot, Emmanuelle, additional, Flamant, Martin, additional, and Lebbe, Celeste, additional

Published
2015
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49. A Phase I-II Study Of The Efficacy and Safety Of Lenalidomide (LEN) Combined To Azacitidine (AZA) In Higher Risk MDS and AML With Del 5q – A Study By The Groupe Francophone Des Myelodysplasies (GFM)

Author

Ades, Lionel, primary, Recher, Christian, additional, Stamatoullas, Aspasia, additional, Bouabdallah, Krimo, additional, Delaunay, Jacques, additional, Dreyfus, Francois, additional, Vey, Norbert, additional, de Renzis, Benoit, additional, Raffoux, Emmanuel, additional, Isnard, Françoise, additional, Samey, Benedicte, additional, Chaffaut, Cendrine, additional, Chevret, Sylvie, additional, and Fenaux, Pierre, additional

Published
2013
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50. Low alcohol consumption influences outcomes in individuals with alcohol-related compensated cirrhosis in a French multicenter cohort.

Author

Louvet, Alexandre, Bourcier, Valérie, Archambeaud, Isabelle, d'Alteroche, Louis, Chaffaut, Cendrine, Oberti, Frédéric, Moreno, Christophe, Roulot, Dominique, Dao, Thông, Moirand, Romain, Duclos-Vallée, Jean-Charles, Goria, Odile, Nguyen-Khac, Eric, Pol, Stanislas, Carbonell, Nicolas, Gournay, Jérôme, Elkrief, Laure, Fouchard-Hubert, Isabelle, Chevret, Sylvie, and Ganne-Carrié, Nathalie

Subjects
*ALCOHOL drinking, *CIRRHOSIS of the liver, *ALCOHOLISM, *PLATELET count, *DRUG abuse
Abstract

The harmful impact of heavy alcohol consumption and recurrence in patients with alcohol-related cirrhosis is long-established, although this is based on old studies. However, the drivers of long-term outcome still need to be clearly investigated. All patients with biopsy-proven compensated alcohol-related cirrhosis included in the CIRRAL cohort (22 centers) were prospectively studied. Prognostic variables of survival and liver event-free survival were assessed using multivariable Cox models with stepwise selection. The prognostic impact of alcohol recurrence during follow-up (computed in glass-years in the same way as pack-years for tobacco) was assessed using a time-dependent covariable. From 2010 to 2016, 650 patients were included. The median age at baseline was 58.4 years, 67.4% were men and the median BMI was 27.8 kg/m2, 63.8% had a history of liver decompensation, and 70.2% had discontinued alcohol. At 5 years, recurrence occurred in 30.9% of abstinent patients and this risk was higher in patients with a history of drug abuse and in those with shorter alcohol discontinuation times. Median survival was 97 months. Age, alcohol consumption at baseline, platelet count and Child-Pugh score >5 were associated with overall and liver event-free survival on multivariate analysis. Alcohol consumption of more than 25 glass-years during follow-up was independently associated with lower survival and with a trend toward lower liver event-free survival, with the risk increasing from 1 glass-year, though not significantly. Simon & Makuch plots confirm the benefit of no alcohol consumption (<1 glass/week) on both outcomes and the dose-dependent impact of alcohol over time. This prospective study in patients with compensated alcohol-related cirrhosis identifies factors predictive of alcohol recurrence during follow-up and shows that moderate alcohol consumption during follow-up negatively impacts outcomes. Patients with alcohol-related cirrhosis should be advised to completely stop drinking alcohol. CIRRAL (NCT01213927) cohort was registered at ClinicalTrials.gov and the full protocol is available at the following link: https://clinicaltrials.gov/ct2/show/NCT01213927. In patients with alcohol-related cirrhosis, data are lacking about the impact of the amount of alcohol consumed on both survival and liver-related events. The present study based on the CIRRAL cohort demonstrates that alcohol recurrence occurs in more than 30% of patients with compensated cirrhosis and that even a moderate recurrence strongly influences outcomes. Patients with compensated alcohol-related cirrhosis should be advised to completely discontinue alcohol consumption, even in small amounts, as the present study shows that no alcohol consumption can be regarded as safe when cirrhosis has developed. [Display omitted] • Alcohol recurrence occurs in more than 30% of cases after a diagnosis of cirrhosis. • A history of drug abuse and a recent alcohol withdrawal are drivers of recurrence. • Even a moderate recurrence influences outcomes in patients with cirrhosis. • Patients with cirrhosis should be advised to stop drinking alcohol, even at low levels. [ABSTRACT FROM AUTHOR]

Published
2023
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